Works matching DE "SIGMA receptors"

Results: 197

Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity.

Published in:

Molecules, 2021, v. 26, n. 13, p. 3860, doi. 10.3390/molecules26133860

By:

Romeo, Giuseppe;
Ciaffaglione, Valeria;
Amata, Emanuele;
Dichiara, Maria;
Calabrese, Loredana;
Vanella, Luca;
Sorrenti, Valeria;
Grosso, Salvo;
D'Amico, Agata Grazia;
D'Agata, Velia;
Intagliata, Sebastiano;
Salerno, Loredana

Publication type:

Article

Sigma-2 Receptor—A Potential Target for Cancer/Alzheimer's Disease Treatment via Its Regulation of Cholesterol Homeostasis.

Published in:

Molecules, 2020, v. 25, n. 22, p. 5439, doi. 10.3390/molecules25225439

By:

Yang, Kai;
Zeng, Cheng;
Wang, Changcai;
Sun, Meng;
Yin, Dan;
Sun, Taolei

Publication type:

Article

Structural Insights into σ1 Receptor Interactions with Opioid Ligands by Molecular Dynamics Simulations.

Published in:

Molecules, 2018, v. 23, n. 2, p. 456, doi. 10.3390/molecules23020456

By:

Kurciński, Mateusz;
Jarończyk, Małgorzata;
Lipiński, Piotr F. J.;
Dobrowolski, Jan Cz.;
Sadlej, Joanna

Publication type:

Article

Sigma Receptor (σR) Ligands with Antiproliferative and Anticancer Activity.

Published in:

Molecules, 2017, v. 22, n. 9, p. 1408, doi. 10.3390/molecules22091408

By:

Georgiadis, Markos-Orestis;
Karoutzou, Olga;
Foscolos, Angeliki-Sofia;
Papanastasiou, Ioannis

Publication type:

Article

Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment.

Published in:

Molecules, 2016, v. 21, n. 9, p. 1210, doi. 10.3390/molecules21091210

By:

Rui, Marta;
Marra, Annamaria;
Pace, Vittorio;
Juza, Markus;
Rossi, Daniela;
Collina, Simona

Publication type:

Article

iPromoter-BnCNN: a novel branched CNN-based predictor for identifying and classifying sigma promoters.

Published in:

Bioinformatics, 2020, v. 36, n. 19, p. 4869, doi. 10.1093/bioinformatics/btaa609

By:

Amin, Ruhul;
Rahman, Chowdhury Rafeed;
Ahmed, Sajid;
Sifat, Md Habibur Rahman;
Liton, Md Nazmul Khan;
Rahman, Md Moshiur;
Khan, Md Zahid Hossain;
Shatabda, Swakkhar

Publication type:

Article

Design, synthesis, chemical characterization, biological evaluation, and docking study of new 1,3,4-oxadiazole homonucleoside analogs.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2020, v. 39, n. 8, p. 1088, doi. 10.1080/15257770.2020.1761982

By:

El Mansouri, Az-Eddine;
Maatallah, Mohamed;
Ait Benhassou, Hassan;
Moumen, Abdeladim;
Mehdi, Ahmad;
Snoeck, Robert;
Andrei, Graciela;
Zahouily, Mohamed;
Lazrek, Hassan B.

Publication type:

Article

Highly Specific Sigma Receptor Ligands Exhibit Anti-Viral Properties in SARS-CoV-2 Infected Cells.

Published in:

Pathogens, 2021, v. 10, n. 11, p. 1514, doi. 10.3390/pathogens10111514

By:

Ostrov, David A.;
Bluhm, Andrew P.;
Li, Danmeng;
Khan, Juveriya Qamar;
Rohamare, Megha;
Rajamanickam, Karthic;
K. Bhanumathy, Kalpana;
Lew, Jocelyne;
Falzarano, Darryl;
Vizeacoumar, Franco J.;
Wilson, Joyce A.;
Mottinelli, Marco;
Kanumuri, Siva Rama Raju;
Sharma, Abhisheak;
McCurdy, Christopher R.;
Norris, Michael H.

Publication type:

Article

Sigma Factor Engineering in Actinoplanes sp. SE50/110: Expression of the Alternative Sigma Factor Gene ACSP50_0507 (σH As) Enhances Acarbose Yield and Alters Cell Morphology.

Published in:

Microorganisms, 2024, v. 12, n. 6, p. 1241, doi. 10.3390/microorganisms12061241

By:

Schlüter, Laura;
Busche, Tobias;
Bondzio, Laila;
Hütten, Andreas;
Niehaus, Karsten;
Schneiker-Bekel, Susanne;
Pühler, Alfred;
Kalinowski, Jörn

Publication type:

Article

The Transposition of Insertion Sequences in Sigma-Factor- and LysR-Deficient Mutants of Deinococcus geothermalis.

Published in:

Microorganisms, 2024, v. 12, n. 2, p. 328, doi. 10.3390/microorganisms12020328

By:

Park, Ji Hyun;
Lee, Sohee;
Shin, Eunjung;
Abdi Nansa, Sama;
Lee, Sung-Jae

Publication type:

Article

The Regulatory Functions of the Multiple Alternative Sigma Factors RpoE, RpoHI, and RpoHII Depend on the Growth Phase in Rhodobacter sphaeroides.

Published in:

Microorganisms, 2023, v. 11, n. 11, p. 2678, doi. 10.3390/microorganisms11112678

By:

Zhang, Jing;
Zheng, Meijia;
Tang, Zizhong;
Zhong, Shanpu;
Bu, Tongliang;
Li, Qingfeng

Publication type:

Article

OxyR Positively Influences Phaseolotoxin Synthesis and Pyoverdin Production in Pseudomonas savastanoi pv. phaseolicola NPS3121.

Published in:

Microorganisms, 2022, v. 10, n. 11, p. 2123, doi. 10.3390/microorganisms10112123

By:

Arvizu-Gómez, Jackeline Lizzeta;
Hernández-Morales, Alejandro;
Juárez-Navarro, Rafael Arnulfo;
Paredes-Tadeo, Juan Diego;
Campos-Guillén, Juan;
Pacheco-Aguilar, Juan Ramiro;
Martínez-Rizo, Abril Bernardette;
González-Reyes, Christian

Publication type:

Article

RpoE Facilitates Stress-Resistance, Invasion, and Pathogenicity of Escherichia coli K1.

Published in:

Microorganisms, 2022, v. 10, n. 5, p. 879, doi. 10.3390/microorganisms10050879

By:

Fan, Yu;
Bai, Jing;
Xi, Daoyi;
Yang, Bin

Publication type:

Article

Chemotherapy-Induced Peripheral Neuropathy: A Recent Update on Pathophysiology and Treatment.

Published in:

Life (2075-1729), 2024, v. 14, n. 8, p. 991, doi. 10.3390/life14080991

By:

Mattar, Marina;
Umutoni, Florence;
Hassan, Marwa A.;
Wamburu, M. Wambui;
Turner, Reagan;
Patton, James S.;
Chen, Xin;
Lei, Wei

Publication type:

Article

M. tuberculosis Transcription Machinery: A Review on the Mycobacterial RNA Polymerase and Drug Discovery Efforts.

Published in:

Life (2075-1729), 2022, v. 12, n. 11, p. 1774, doi. 10.3390/life12111774

By:

Stephanie, Filia;
Tambunan, Usman Sumo Friend;
Siahaan, Teruna J.

Publication type:

Article

In Silico Study of Cucurbita maxima Compounds as Potential Therapeutics Against Schistosomiasis.

Published in:

Bioinformatics & Biology Insights, 2022, p. 1, doi. 10.1177/11779322221100741

By:

Mtemeli, Floryn Lynorah;
Shoko, Ryman;
Ndlovu, Joice;
Mugumbate, Grace

Publication type:

Article

In Silico Study of Cucurbita maxima Compounds as Potential Therapeutics Against Schistosomiasis.

Published in:

Bioinformatics & Biology Insights, 2022, v. 16, p. 1, doi. 10.1177/11779322221100741

By:

Mtemeli, Floryn Lynorah;
Shoko, Ryman;
Ndlovu, Joice;
Mugumbate, Grace

Publication type:

Article

Sigma-receptor-1 and mGluR5 may participate in Rac-dependent oncogenesis through modulation of macrophage activity.

Published in:

Biopolymers & Cell, 2015, p. 18

By:

Natsvlishvili., N.;
Shanshiashvili, L.;
Mikeladze, D.

Publication type:

Article

Sigma1 Receptor Inhibits TRPC1-Mediated Ca2+ Entry That Promotes Dopaminergic Cell Death.

Published in:

Cellular & Molecular Neurobiology, 2021, v. 41, n. 6, p. 1245, doi. 10.1007/s10571-020-00892-5

By:

Sun, Yuyang;
Sukumaran, Pramod;
Singh, Brij B.

Publication type:

Article

Alzheimer's disease and clinical trials.

Published in:

Journal of Basic & Clinical Physiology & Pharmacology, 2024, v. 35, n. 1/2, p. 31, doi. 10.1515/jbcpp-2023-0264

By:

Paul, Deepraj;
Agrawal, Rohini;
Singh, Swati

Publication type:

Article

A Selective M1 and M3 Receptor Antagonist, Penehyclidine Hydrochloride, Exerts Antidepressant-Like Effect in Mice.

Published in:

Neurochemical Research, 2019, v. 44, n. 12, p. 2723, doi. 10.1007/s11064-019-02891-5

By:

Sun, Xiaojing;
Sun, Congcong;
Zhai, Lingyan;
Dong, Wei

Publication type:

Article

A Natural Product with High Affinity to Sigma and 5-HT7 Receptors as Novel Therapeutic Drug for Negative and Cognitive Symptoms of Schizophrenia.

Published in:

Neurochemical Research, 2019, v. 44, n. 11, p. 2536, doi. 10.1007/s11064-019-02873-7

By:

Wang, Lien;
Zhang, Yan;
Wang, Chaoran;
Zhang, Xiuli;
Wang, Zhiwei;
Liang, Xinmiao;
Alachkar, Amal;
Civelli, Olivier

Publication type:

Article

Regulation of lignocellulose degradation in microorganisms.

Published in:

2023

By:

Gurovic, María Soledad Vela;
Viceconte, Fatima Regina;
Bidegain, Maximiliano Andres;
Dietrich, Julián

Publication type:

Literature Review

Characterization of tritiated JNJ‐GluN2B‐5 (3‐[3H] 1‐(azetidin‐1‐yl)‐2‐(6‐(4‐fluoro‐3‐methyl‐phenyl)pyrrolo[3,2‐b]pyridin‐1‐yl)ethanone), a high affinity GluN2B radioligand with selectivity over sigma receptors

Published in:

Journal of Neurochemistry, 2024, v. 168, n. 9, p. 2654, doi. 10.1111/jnc.16129

By:

Schoellerman, Jeffrey;
Lord, Brian;
Bhattacharya, Anindya;
Stenne, Brice;
Wall, Jessica L.;
Rech, Jason;
Letavic, Michael;
Bonaventure, Pascal;
Balana, Bartosz

Publication type:

Article

The multiplicity of thioredoxin systems meets the specific lifestyles of Clostridia.

Published in:

PLoS Pathogens, 2024, v. 20, n. 2, p. 1, doi. 10.1371/journal.ppat.1012001

By:

Anjou, Cyril;
Lotoux, Aurélie;
Zhukova, Anna;
Royer, Marie;
Caulat, Léo C.;
Capuzzo, Elena;
Morvan, Claire;
Martin-Verstraete, Isabelle

Publication type:

Article

Activation of ChvG-ChvI regulon by cell wall stress confers resistance to β-lactam antibiotics and initiates surface spreading in Agrobacterium tumefaciens.

Published in:

PLoS Genetics, 2022, v. 18, n. 12, p. 1, doi. 10.1371/journal.pgen.1010274

By:

Williams, Michelle A.;
Bouchier, Jacob M.;
Mason, Amara K.;
Brown, Pamela J. B.

Publication type:

Article

The essential Rhodobacter sphaeroides CenKR two-component system regulates cell division and envelope biosynthesis.

Published in:

PLoS Genetics, 2022, v. 18, n. 6, p. 1, doi. 10.1371/journal.pgen.1010270

By:

Lakey, Bryan D.;
Myers, Kevin S.;
Alberge, François;
Mettert, Erin L.;
Kiley, Patricia J.;
Noguera, Daniel R.;
Donohue, Timothy J.

Publication type:

Article

Antidepressant-like action of the hydromethanolic flower extract of Tagetes erecta L. in mice and its possible mechanism of action.

Published in:

Indian Journal of Pharmacology, 2013, v. 45, n. 4, p. 386, doi. 10.4103/0253-7613.115026

By:

Khulbe, Aarti;
Pandey, Savita;
Sah, Sangeeta Pilkhwal

Publication type:

Article

Design, Synthesis, and Cytotoxic Assessment of New Haloperidol Analogues as Potential Anticancer Compounds Targeting Sigma Receptors.

Published in:

Molecules, 2024, v. 29, n. 11, p. 2697, doi. 10.3390/molecules29112697

By:

Zampieri, Daniele;
Romano, Maurizio;
Fortuna, Sara;
Amata, Emanuele;
Dichiara, Maria;
Cosentino, Giuseppe;
Marrazzo, Agostino;
Mamolo, Maria Grazia

Publication type:

Article

3,3-Disubstituted 3,4-Dihydro-1,2,4-benzotriazines: Chemistry, Biological Activity, and Affinity to Sigma Receptors.

Published in:

Molecules, 2024, v. 29, n. 1, p. 132, doi. 10.3390/molecules29010132

By:

Sparatore, Fabio;
Sparatore, Anna

Publication type:

Article

Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands.

Published in:

Molecules, 2023, v. 28, n. 8, p. 3431, doi. 10.3390/molecules28083431

By:

Zampieri, Daniele;
Calabretti, Antonella;
Romano, Maurizio;
Fortuna, Sara;
Collina, Simona;
Amata, Emanuele;
Dichiara, Maria;
Marrazzo, Agostino;
Mamolo, Maria Grazia

Publication type:

Article

2-Phenethylamines in Medicinal Chemistry: A Review.

Published in:

Molecules, 2023, v. 28, n. 2, p. 855, doi. 10.3390/molecules28020855

By:

Nieto, Carlos T.;
Manchado, Alejandro;
Belda, Leland;
Diez, David;
Garrido, Narciso M.

Publication type:

Article

Hierarchical Virtual Screening and Binding Free Energy Prediction of Potential Modulators of Aedes Aegypti Odorant-Binding Protein 1.

Published in:

Molecules, 2022, v. 27, n. 20, p. 6777, doi. 10.3390/molecules27206777

By:

Neto, Moysés F. A.;
Campos, Joaquín M.;
Cerqueira, Amanda P. M.;
de Lima, Lucio R.;
Da Costa, Glauber V.;
Ramos, Ryan Da S.;
Junior, Jairo T. Magalhães;
Santos, Cleydson B. R.;
Leite, Franco H. A.

Publication type:

Article

Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer.

Published in:

Molecules, 2022, v. 27, n. 14, p. N.PAG, doi. 10.3390/molecules27144327

By:

Tesei, Anna;
Cortesi, Michela;
Bedeschi, Martina;
Marino, Noemi;
Rossino, Giacomo;
Listro, Roberta;
Rossi, Daniela;
Linciano, Pasquale;
Collina, Simona

Publication type:

Article

Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain.

Published in:

Molecules, 2022, v. 27, n. 11, p. 3617, doi. 10.3390/molecules27113617

By:

Wilson, Lisa L.;
Alleyne, Amy R.;
Eans, Shainnel O.;
Cirino, Thomas J.;
Stacy, Heather M.;
Mottinelli, Marco;
Intagliata, Sebastiano;
McCurdy, Christopher R.;
McLaughlin, Jay P.

Publication type:

Article

Chalcone Scaffolds Exhibiting Acetylcholinesterase Enzyme Inhibition: Mechanistic and Computational Investigations.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3181, doi. 10.3390/molecules27103181

By:

Malik, Yossra A.;
Awad, Talal Ahmed;
Abdalla, Mohnad;
Yagi, Sakina;
Alhazmi, Hassan A.;
Ahsan, Waquar;
Albratty, Mohammed;
Najmi, Asim;
Muhammad, Shabbir;
Khalid, Asaad

Publication type:

Article

RECEPTOR RELATED PHARMACOLOGICAL ACTIVITIES OF HYPERICUM PERFORATUM L.

Published in:

Journal of Research in Pharmacy, 2023, v. 27, p. 43

By:

HAMURTEKİN, Emre

Publication type:

Article

Identification of the growth cone as a probe and driver of neuronal migration in the injured brain.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45825-8

By:

Nakajima, Chikako;
Sawada, Masato;
Umeda, Erika;
Takagi, Yuma;
Nakashima, Norihiko;
Kuboyama, Kazuya;
Kaneko, Naoko;
Yamamoto, Satoaki;
Nakamura, Haruno;
Shimada, Naoki;
Nakamura, Koichiro;
Matsuno, Kumiko;
Uesugi, Shoji;
Vepřek, Nynke A.;
Küllmer, Florian;
Nasufović, Veselin;
Uchiyama, Hironobu;
Nakada, Masaru;
Otsuka, Yuji;
Ito, Yasuyuki

Publication type:

Article

A case of platelet δ-granule defect identified by decreased CD63 expression and decreased serotonin release measured by flow cytometry and liquid chromatography tandem mass spectrometry.

Published in:

2024

By:

Nissen, Peter H.;
Mikkelsen, Torben Stamm;
Højskov, Carsten Schriver;
Højbjerg, Johanne Andersen

Publication type:

Case Study

In vitro screening of major neurotransmitter systems possibly involved in the mechanism of action of antibodies to S100 protein in releasedactive form.

Published in:

Neuropsychiatric Disease & Treatment, 2015, v. 11, p. 2837, doi. 10.2147/NDT.S92456

By:

Gorbunov, Evgeniy A.;
Ertuzun, Irina A.;
Kachaeva, Evgeniya V.;
Tarasov, Sergey A.;
Epstein, Oleg I.

Publication type:

Article

Sigma Metrics: A Valuable Tool for Evaluating the Performance of Internal Quality Control in Laboratory.

Published in:

Journal of Laboratory Physicians, 2021, v. 13, n. 4, p. 328, doi. 10.1055/s-0041-1731145

By:

Kashyap, Akriti;
Sampath, Sangeetha;
Tripathi, Preeti;
Sen, Arijit

Publication type:

Article

Optimal graph-based and Simplified Molecular Input Line Entry System-based descriptors for quantitative structure-activity relationship analysis of arylalkylaminoalcohols, arylalkenylamines, and arylalkylamines as σ1 receptor ligands.

Published in:

Journal of Chemometrics, 2015, v. 29, n. 1, p. 13, doi. 10.1002/cem.2650

By:

Quesada‐Romero, Luisa;
Mena‐Ulecia, Karel;
Zuñiga, Matias;
De‐la‐Torre, Pedro;
Rossi, Daniela;
Tiznado, William;
Collina, Simona;
Caballero, Julio

Publication type:

Article

ETHYLAMINES WITH HIGH AFFINITY AND SELECTIVITY FOR SIGMA RECEPTORS ATTENUATE COCAINE-INDUCED BEHAVIORS IN MICE.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A778, doi. 10.1096/fasebj.21.6.a778-c

By:

Matsumoto, Rae R.;
Diers, Jeffrey A.;
Coop, Andrew

Publication type:

Article

RALATIONSHIP BETWEEN THE DEVELOPMENT AND EXPRESSION OF COCAINE-INDUCED BEHAVIORAL SENSITIZATION AND CHANGES IN FRA-2 AND SIGMA RECEPTOR GENE AND PROTEIN EXPRESSION: MODULATION BỲ A SIGMA RECEPTOR ANTAGONIST.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A778

By:

Jiajia Wang;
Yun Liu;
Matsumoto, Rae

Publication type:

Article

Variations in apolipoprotein D and sigma non-opioid intracellular receptor 1 genes with relation to risk, severity and outcome of ischemic stroke.

Published in:

BMC Neurology, 2014, v. 14, n. 1, p. 1, doi. 10.1186/s12883-014-0191-2

By:

Lövkvist, Håkan;
Jönsson, Ann-Cathrin;
Luthman, Holger;
Jood, Katarina;
Jern, Christina;
Wieloch, Tadeusz;
Lindgren, Arne

Publication type:

Article

Sigma receptor ligands haloperidol and ifenprodil attenuate hypoxia induced dopamine release in rat striatum.

Published in:

Neurological Research, 2022, v. 44, n. 10, p. 927, doi. 10.1080/01616412.2022.2072100

By:

Gursoy, Murat;
Gul, Zulfiye;
Buyukuysal, R. Levent

Publication type:

Article

Insights into the biased activity of dextromethorphan and haloperidol towards SARS-CoV-2 NSP6: in silico binding mechanistic analysis.

Published in:

Journal of Molecular Medicine, 2020, v. 98, n. 12, p. 1659, doi. 10.1007/s00109-020-01980-1

By:

Pandey, Preeti;
Prasad, Kartikay;
Prakash, Amresh;
Kumar, Vijay

Publication type:

Article

Neuromodulatory mechanisms of N,N-dimethyltryptamine: a narrative review.

Published in:

Brain Network & Modulation (BNM), 2023, v. 2, n. 3, p. 53, doi. 10.4103/2773-2398.386227

By:

Hidalgo Jiménez, Javier

Publication type:

Article

In silico-based analysis and in vitro experiments identify SIGMAR1 as a potential marker of putative lung cancer stem cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02394-6

By:

Horie, Tetsuhiro;
Kuwano, Ayane;
Sakamoto, Takuya;
Nakamura, Yuka;
Yamaguchi, Kayoko;
Tanida, Ikuhiro;
Osawa, Satoshi;
Yasumoto, Kazuo;
Ishigaki, Yasuhito

Publication type:

Article

Sigma Receptor Type 1 Gene Variation in a Group of Polish Patients with Alzheimer’s Disease and Mild Cognitive Impairment.

Published in:

Dementia & Geriatric Cognitive Disorders, 2007, v. 23, n. 6, p. 432, doi. 10.1159/000101990

By:

Maruszak, Aleksandra;
Safranow, Krzysztof;
Gacia, Magdalena;
Gabryelewicz, Tomasz;
Słowik, Agnieszka;
Styczyńska, Maria;
Pepłońska, Beata;
Golan, Maciej P.;
Żekanowski, Cezary;
Barcikowska, Maria

Publication type:

Article