Works about SHIKONIN
Results: 271
Preparation of antibacterial/antiviral and pH responsive nanofiber membranes based on cellulose acetate.
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- Journal of Polymer Research, 2025, v. 32, n. 2, p. 1, doi. 10.1007/s10965-025-04278-3
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- Article
The Role of miR-146a in the Anti-Inflammatory and Antioxidant Effects of Shikonin on Gingival Fibroblasts.
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- Applied Sciences (2076-3417), 2025, v. 15, n. 4, p. 2019, doi. 10.3390/app15042019
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- Article
Lung Cancer-Targeted [<sup>131</sup>I]-Iodoshikonin as Theranostic Agent: Radiolabeling, In Vivo Pharmacokinetics and Biodistribution.
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- Pharmaceutical Chemistry Journal, 2022, v. 55, n. 11, p. 1163, doi. 10.1007/s11094-022-02553-x
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- Article
Differential relieving effects of shikonin and its derivatives on inflammation and mucosal barrier damage caused by ulcerative colitis.
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- PeerJ, 2021, p. 1, doi. 10.7717/peerj.10675
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- Article
Echium plantagineum L. hairy root cultures for the production of anticancer shikonin derivatives.
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- Biotechnologia, 2018, v. 99, n. 3, p. 321
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- Article
紫草素对四氯化碳诱导的肝纤维化大鼠TGF-β1的影响.
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- Journal of Pharmaceutical Practice & Service, 2018, v. 36, n. 5, p. 453, doi. 10.3969/j.issn.1006-0111.2018.05.016
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- Article
不同剂量紫草素对雌激素加孕激素负荷法建立的子宫肌瘤大鼠的 子宫组织 ER, PR 和 p-ERK 的蛋白表达影响.
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- Progress in Modern Biomedicine, 2023, v. 23, n. 4, p. 619, doi. 10.13241/j.cnki.pmb.2023.04.004
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- Article
Natural Compounds Oridonin and Shikonin Exhibit Potentially Beneficial Regulatory Effects on Select Functions of Microglia.
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- Brain Sciences (2076-3425), 2024, v. 14, n. 4, p. 328, doi. 10.3390/brainsci14040328
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- Article
Characterization of Shikonin Derivative Secretion in Lithospermum erythrorhizon Hairy Roots as a Model of Lipid-Soluble Metabolite Secretion from Plants.
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- Frontiers in Plant Science, 2016, p. 1, doi. 10.3389/fpls.2016.01066
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- Article
Development of a Porcine Full-Thickness Burn Hypertrophic Scar Model and Investigation of the Effects of Shikonin on Hypertrophic Scar Remediation.
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- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00590
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- Article
Effect of Shikonin Against Candida albicans Biofilms.
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- Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.01085
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- Article
Dual treatment with shikonin and temozolomide reduces glioblastoma tumor growth, migration and glial-to-mesenchymal transition.
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- Cellular Oncology (2211-3428), 2017, v. 40, n. 3, p. 247, doi. 10.1007/s13402-017-0320-1
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- Article
Shikonin Induces Autophagy and Apoptosis in Esophageal Cancer EC9706 Cells by Regulating the AMPK/mTOR/ULK Axis.
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- Analytical Cellular Pathology: Cellular Oncology, 2024, v. 2024, p. 1, doi. 10.1155/2024/7752299
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- Article
Shikonin Controls the Differentiation of CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T Cells by Inhibiting AKT/mTOR Pathway.
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- Inflammation, 2019, v. 42, n. 4, p. 1215, doi. 10.1007/s10753-019-00982-7
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- Article
Shikonin Inhibits Inflammatory Cytokine Production in Human Periodontal Ligament Cells.
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- Inflammation, 2016, v. 39, n. 3, p. 1124, doi. 10.1007/s10753-016-0344-0
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- Article
Transgenic studies reveal the positive role of LeEIL-1 in regulating shikonin biosynthesis in Lithospermum erythrorhizon hairy roots.
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- BMC Plant Biology, 2016, v. 16, p. 1, doi. 10.1186/s12870-016-0812-6
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- Article
Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways.
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- BMC Cell Biology, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12860-018-0179-7
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- Article
Research progress on the structural and anti-colorectal malignant tumor properties of Shikonin.
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- Journal of Cancer Research & Therapeutics, 2024, v. 20, n. 7, p. 1957, doi. 10.4103/jcrt.jcrt_933_24
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- Article
β, β-Dimethylacrylshikonin induces mitochondria-dependent apoptosis of human lung adenocarcinoma cells in vitro via p38 pathway activation.
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- Acta Pharmacologica Sinica, 2015, v. 36, n. 1, p. 131, doi. 10.1038/aps.2014.108
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- Article
Mechanisms Behind the Inhibition of Lung Adenocarcinoma Cell by Shikonin.
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- Cell Biochemistry & Biophysics, 2014, v. 70, n. 2, p. 1459, doi. 10.1007/s12013-014-0083-5
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- Article
Cross‐Linking Interpenetration Polyacrylic Acid‐Starch Porous Sheet Combined with Anthocyanin and Shikonin for Freshness Monitoring.
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- Starch / Staerke, 2024, v. 76, n. 7/8, p. 1, doi. 10.1002/star.202300244
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- Article
Anoikis and cancer cell differentiation: novel modes of shikonin derivatives anticancer action in vitro.
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- Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-023-09093-x
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- Article
Shikonin improves the effectiveness of PD-1 blockade in colorectal cancer by enhancing immunogenicity via Hsp70 upregulation.
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- Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-023-09056-2
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- Article
In vitro antifungal activity of Shikonin against Candida albicans by inducing cellular apoptosis and necrosis.
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- Molecular Biology Reports, 2023, v. 50, n. 2, p. 1079, doi. 10.1007/s11033-022-08093-7
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- Article
Synergy between sublethal doses of shikonin and metformin fully inhibits breast cancer cell migration and reverses epithelial-mesenchymal transition.
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- Molecular Biology Reports, 2022, v. 49, n. 6, p. 4307, doi. 10.1007/s11033-022-07265-9
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- Article
A Potent Anticancer Agent of Shikonin Derivative Targeting Tubulin.
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- Chirality, 2015, v. 27, n. 3, p. 274, doi. 10.1002/chir.22425
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- Article
Design and Synthesis of Fluoroacylshikonin as an Anticancer Agent.
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- Chirality, 2013, v. 25, n. 11, p. 757, doi. 10.1002/chir.22209
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- Article
Shikonin suppresses NEAT1 and Akt signaling in treating paclitaxel-resistant non-small cell of lung cancer.
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- Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00152-8
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- Article
Shikonin induces odontoblastic differentiation of dental pulp stem cells via AKT–mTOR signaling in the presence of CD44.
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- Connective Tissue Research, 2021, v. 62, n. 6, p. 689, doi. 10.1080/03008207.2020.1865937
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- Article
Explore of Molecular Mechanism on Fungal Elicitors Regulating Shikonin Synthesis.
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- Journal of Agricultural Science & Technology (1008-0864), 2024, v. 26, n. 1, p. 78, doi. 10.13304/j.nykjdb.2022.0622
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- Article
Shikonin regulates autophagy via the AMPK/mTOR pathway and reduces apoptosis of human umbilical cord mesenchymal stem cells to improve survival in tissues surrounding brain contusion.
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- Experimental & Therapeutic Medicine, 2021, v. 22, n. 6, p. N.PAG, doi. 10.3892/etm.2021.10910
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- Article
Shikonin attenuates H<sub>2</sub>O<sub>2</sub>-induced oxidative injury in HT29 cells via antioxidant activities and the inhibition of mitochondrial pathway-mediated apoptosis.
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- Experimental & Therapeutic Medicine, 2021, v. 22, n. 4, p. N.PAG, doi. 10.3892/etm.2021.10552
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- Article
Non-cytotoxic doses of shikonin inhibit lipopolysaccharide-induced TNF-α expression via activation of the AMP-activated protein kinase signaling pathway.
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- Experimental & Therapeutic Medicine, 2020, v. 20, n. 5, p. N.PAG, doi. 10.3892/etm.2020.9173
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- Article
Shikonin causes apoptosis by disrupting intracellular calcium homeostasis and mitochondrial function in human hepatoma cells.
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- Experimental & Therapeutic Medicine, 2018, v. 15, n. 2, p. 1484, doi. 10.3892/etm.2017.5591
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- Article
Shikonin inhibits inflammation and chondrocyte apoptosis by regulation of the PI3K/Akt signaling pathway in a rat model of osteoarthritis.
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- Experimental & Therapeutic Medicine, 2016, v. 12, n. 4, p. 2735, doi. 10.3892/etm.2016.3642
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- Article
Cbl-b-regulated extracellular signal-regulated kinase signaling is involved in the shikonin-induced apoptosis of lung cancer cells in vitro.
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- Experimental & Therapeutic Medicine, 2015, v. 9, n. 4, p. 1265, doi. 10.3892/etm.2015.2283
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- Article
Shikonin reduces endometriosis by inhibiting RANTES secretion and mononuclear macrophage chemotaxis.
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- Experimental & Therapeutic Medicine, 2014, v. 7, n. 3, p. 685, doi. 10.3892/etm.2013.1458
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- Article
Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1490759
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- Article
Excretion of triacylglycerol as a matrix lipid facilitating apoplastic accumulation of a lipophilic metabolite shikonin.
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- Journal of Experimental Botany, 2023, v. 74, n. 1, p. 104, doi. 10.1093/jxb/erac405
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- Article
Shikonin Exerts an Antileukemia Effect against FLT3-ITD Mutated Acute Myeloid Leukemia Cells via Targeting FLT3 and Its Downstream Pathways.
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- Acta Haematologica, 2024, v. 147, n. 3, p. 310, doi. 10.1159/000534101
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- Article
Regioselective semi-synthesis of 6-isomers of 5,8-O-dimethyl ether of shikonin derivatives via an 'intramolecular ring-closing/ ring-opening' strategy as potent anticancer agents.
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- Chemistry Central Journal, 2017, v. 11, p. 1, doi. 10.1186/s13065-017-0306-0
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- Article
Expression of Concern: Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR-NF-κB signalling pathway in human epidermoid carcinoma A431 cells.
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- 2023
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- Correction Notice
Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis.
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- Bioscience Reports, 2021, v. 41, n. 1, p. 1, doi. 10.1042/BSR20203834
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- Article
Shikonin causes cell-cycle arrest and induces apoptosis by regulating the EGFR-NF-kB signalling pathway in human epidermoid carcinoma A431 cells.
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- Bioscience Reports, 2015, v. 35, n. 2, p. 1, doi. 10.1042/BSR20150002
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- Article
Preparation, cellular uptake and angiogenic suppression of shikonin-containing liposomes in vitro and in vivo.
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- Bioscience Reports, 2013, v. 33, n. 2, p. 207, doi. 10.1042/BSR20120065
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- Article
Shikonin: Extraction, properties and applications in active and intelligent packaging.
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- Packaging Technology & Science, 2022, v. 35, n. 12, p. 863, doi. 10.1002/pts.2687
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- Article
Protective Effect of Shikonin in Experimental Ischemic Stroke: Attenuated TLR4, p-p38MAPK, NF-κB, TNF-α and MMP-9 Expression, Up-Regulated Claudin-5 Expression, Ameliorated BBB Permeability.
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- Neurochemical Research, 2014, v. 39, n. 1, p. 97, doi. 10.1007/s11064-013-1194-x
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- Article
Shikonin Protects Dopaminergic Cell Line PC12 Against 6-Hydroxydopamine-Mediated Neurotoxicity Via Both Glutathione-Dependent and Independent Pathways and by Inhibiting Apoptosis.
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- Neurochemical Research, 2013, v. 38, n. 8, p. 1590, doi. 10.1007/s11064-013-1061-9
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- Article
Antinociceptive properties of shikonin: in vitro and in vivo studies.
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- Canadian Journal of Physiology & Pharmacology, 2016, v. 94, n. 7, p. 788, doi. 10.1139/cjpp-2015-0465
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- Article
Shikonin inhibits TNF-α-induced growth and invasion of rat aortic vascular smooth muscle cells.
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- Canadian Journal of Physiology & Pharmacology, 2015, v. 93, n. 8, p. 615, doi. 10.1139/cjpp-2014-0464
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- Article