Works matching DE "SEPARASE"

Results: 26

Deciphering the modes of human separase inhibition by securin and CDK1-CCNB1.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 4, p. 1, doi. 10.1080/23723556.2021.1975473

By:

Raia, Pierre;
Yu, Jun;
Boland, Andreas

Publication type:

Article

Biology and insights into the role of cohesin protease separase in human malignancies.

Published in:

Biological Reviews, 2017, v. 92, n. 4, p. 2070, doi. 10.1111/brv.12321

By:

Zhang, Nenggang;
Pati, Debananda

Publication type:

Article

Sister centromere fusion during meiosis I depends on maintaining cohesins and destabilizing microtubule attachments.

Published in:

PLoS Genetics, 2019, v. 15, n. 5, p. 1, doi. 10.1371/journal.pgen.1008072

By:

Wang, Lin-Ing;
Das, Arunika;
McKim, Kim S.

Publication type:

Article

Cdk1 phosphorylation of Esp1/Separase functions with PP2A and Slk19 to regulate pericentric Cohesin and anaphase onset.

Published in:

PLoS Genetics, 2018, v. 14, n. 3, p. 1, doi. 10.1371/journal.pgen.1007029

By:

Lianga, Noel;
Doré, Carole;
Kennedy, Erin K.;
Yeh, Elaine;
Williams, Elizabeth C.;
Fortinez, Camille Marie;
Wang, Alick;
Bloom, Kerry S.;
Rudner, Adam D.

Publication type:

Article

Overexpression and constitutive nuclear localization of cohesin protease Separase protein correlates with high incidence of relapse and reduced overall survival in glioblastoma multiforme.

Published in:

Journal of Neuro-Oncology, 2014, v. 119, n. 1, p. 27, doi. 10.1007/s11060-014-1458-6

By:

Mukherjee, Malini;
Byrd, Tiara;
Brawley, Vita;
Bielamowicz, Kevin;
Li, Xiao-Nan;
Merchant, Fatima;
Maitra, Saurabh;
Sumazin, Pavel;
Fuller, Greg;
Kew, Yvonne;
Sun, David;
Powell, Suzanne;
Ahmed, Nabil;
Zhang, Nenggang;
Pati, Debananda

Publication type:

Article

Synthesis of new 2 H-benzimidazole 1,3-dioxide derivatives analogous to separase inhibitor (Sepin-1).

Published in:

Russian Journal of Organic Chemistry, 2017, v. 53, n. 12, p. 1896, doi. 10.1134/S1070428017120223

By:

Chugunova, E.;
Akylbekov, N.;
Gaziev, M.;
Samsonov, V.;
Dobrynin, A.;
Burilov, A.

Publication type:

Article

Centrosome reduction in newly-generated tetraploid cancer cells obtained by separase depletion.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65975-1

By:

Galofré, Claudia;
Asensio, Elena;
Ubach, Maria;
Torres, Irianna M.;
Quintanilla, Isabel;
Castells, Antoni;
Camps, Jordi

Publication type:

Article

Structural Insights into Separase Architecture and Substrate Recognition through Computational Modelling of Caspase-Like and Death Domains.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pcbi.1004548

By:

Winter, Anja;
Schmid, Ralf;
Bayliss, Richard

Publication type:

Article

The Metabolism of Separase Inhibitor Sepin-1 in Human, Mouse, and Rat Liver Microsomes.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00313

By:

Li, Feng;
Zhang, Nenggang;
Gorantla, Siddharth;
Gilbertson, Scott R.;
Pati, Debananda

Publication type:

Article

Conservation of the separase regulatory domain.

Published in:

Biology Direct, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13062-018-0210-0

By:

Melesse, Michael;
Bembenek, Joshua N.;
Zhulin, Igor B.

Publication type:

Article

Increased separase activity and occurrence of centrosome aberrations concur with transformation of MDS.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191734

By:

Ruppenthal, Sabrina;
Kleiner, Helga;
Nolte, Florian;
Fabarius, Alice;
Hofmann, Wolf-Karsten;
Nowak, Daniel;
Seifarth, Wolfgang

Publication type:

Article

Condensin in Chromatid Cohesion and Segregation.

Published in:

Cytogenetic & Genome Research, 2016, v. 147, n. 4, p. 212, doi. 10.1159/000444868

By:

Uchiyama, Susumu;
Fukui, Kiichi

Publication type:

Article

Demystifying Aurora B.

Published in:

Journal of Cell Biology, 2015, v. 209, n. 2, p. 189, doi. 10.1083/jcb.2092fta

By:

Sedwick, Caitlin

Publication type:

Article

Separases: biochemistry and function.

Published in:

Physiologia Plantarum, 2012, v. 145, n. 1, p. 67, doi. 10.1111/j.1399-3054.2011.01550.x

By:

Moschou, Panagiotis N.;
Bozhkov, Peter V.

Publication type:

Article

Genetic Identification of Separase Regulators in Caenorhabditis elegans.

Published in:

G3: Genes | Genomes | Genetics, 2018, v. 8, n. 2, p. 695, doi. 10.1534/g3.117.300298

By:

Melesse, Michael;
Sloan, Dillon E.;
Benthal, Joseph T.;
Caylor, Quincey;
Gosine, Krishen;
Xiaofei Bai;
Bembenek, Joshua N.

Publication type:

Article

Integrity of the Pericentriolar Material Is Essential for Maintaining Centriole Association during M Phase.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0138905

By:

Seo, Mi Young;
Jang, Wonyul;
Rhee, Kunsoo

Publication type:

Article

Measurement of Separase Proteolytic Activity in Single Living Cells by a Fluorogenic Flow Cytometry Assay.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0133769

By:

Haaß, Wiltrud;
Kleiner, Helga;
Müller, Martin C.;
Hofmann, Wolf-Karsten;
Fabarius, Alice;
Seifarth, Wolfgang

Publication type:

Article

Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129648

By:

Haaß, Wiltrud;
Kleiner, Helga;
Weiß, Christel;
Haferlach, Claudia;
Schlegelberger, Brigitte;
Müller, Martin C.;
Hehlmann, Rüdiger;
Hofmann, Wolf-Karsten;
Fabarius, Alice;
Seifarth, Wolfgang;
null, null

Publication type:

Article

Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125382

By:

Monen, Joost;
Hattersley, Neil;
Muroyama, Andrew;
Stevens, Deanna;
Oegema, Karen;
Desai, Arshad

Publication type:

Article

Protease-Dead Separase Is Dominant Negative in the C. elegans Embryo.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108188

By:

Mitchell, Diana M.;
Uehlein-Klebanow, Lindsey R.;
Bembenek, Joshua N.

Publication type:

Article

The Proteolytic Activity of Separase in BCR-ABL-Positive Cells Is Increased by Imatinib.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042863

By:

Haaß, Wiltrud;
Stehle, Michael;
Nittka, Stefanie;
Giehl, Michelle;
Schrotz-King, Petra;
Fabarius, Alice;
Hofmann, Wolf-Karsten;
Seifarth, Wolfgang;
Moura, Ivan Cruz

Publication type:

Article

Separase Is Required for Homolog and Sister Disjunction during Drosophila melanogaster Male Meiosis, but Not for Biorientation of Sister Centromeres.

Published in:

PLoS Genetics, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pgen.1005996

By:

Blattner, Ariane C.;
Chaurasia, Soumya;
McKee, Bruce D.;
Lehner, Christian F.

Publication type:

Article

A Role for the Budding Yeast Separase, Esp1, in Ty1 Element Retrotransposition.

Published in:

PLoS Genetics, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.pgen.1005109

By:

Ho, Krystina L.;
Ma, Lina;
Cheung, Stephanie;
Manhas, Savrina;
Fang, Nancy;
Wang, Kaiqian;
Young, Barry;
Loewen, Christopher;
Mayor, Thibault;
Measday, Vivien

Publication type:

Article

Sensors at Centrosomes Reveal Determinants of Local Separase Activity.

Published in:

PLoS Genetics, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.pgen.1004672

By:

Agircan, Fikret Gurkan;
Schiebel, Elmar

Publication type:

Article

Cutting in the middleman: hidden substrates at the interface between proteases and plant development.

Published in:

New Phytologist, 2018, v. 218, n. 3, p. 916, doi. 10.1111/nph.14501

By:

Liu, Chen;
Moschou, Panagiotis N.

Publication type:

Article

Critical Differences between Isoforms of Securin Reveal Mechanisms of Separase Regulation.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 17, p. 3400, doi. 10.1128/MCB.00057-13

By:

Xianxian Han;
Poon, Randy Y. C.

Publication type:

Article