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Two amino acids missing of MtrA resulted in increased erythromycin level and altered phenotypes in Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2019, v. 103, n. 11, p. 4539, doi. 10.1007/s00253-019-09825-9
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Transcriptome-guided target identification of the TetR-like regulator SACE_5754 and engineered overproduction of erythromycin in Saccharopolyspora erythraea.
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- Journal of Biological Engineering, 2019, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13036-018-0135-2
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Lysine propionylation modulates the transcriptional activity of phosphate regulator PhoP in Saccharopolyspora erythraea.
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- Molecular Microbiology, 2018, v. 110, n. 4, p. 648, doi. 10.1111/mmi.14122
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High-throughput optimization of the chemically defined synthetic medium for the production of erythromycin A.
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- Bioprocess & Biosystems Engineering, 2018, v. 41, n. 10, p. 1529, doi. 10.1007/s00449-018-1980-6
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STATISTICAL OPTIMIZATION OF ERYTHROMYCIN PRODUCTION BY Saccharopolyspora erythraea UNDER SOLID STATE FERMENTATION OF AGRO-INDUSTRIAL MATERIALS USING RESPONSE SURFACE METHODOLOGY.
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- Journal of Microbiology, Biotechnology & Food Sciences, 2018, v. 8, n. 1, p. 692, doi. 10.15414/jmbfs.2018.8.1.692-697
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Metabolomics for industrial fermentation.
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- Bioprocess & Biosystems Engineering, 2018, v. 41, n. 7, p. 1073, doi. 10.1007/s00449-018-1967-3
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In silico reconstruction and experimental validation of Saccharopolyspora erythraea genome-scale metabolic model iZZ1342 that accounts for 1685 ORFs.
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- Bioresources & Bioprocessing, 2018, v. 5, n. 1, p. 1, doi. 10.1186/s40643-018-0212-x
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Overproduction of Erythromycin by Ultraviolet Mutagenesis and Expression of ermE Gene in Saccharopolyspora erythraea.
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- Assay & Drug Development Technologies, 2017, v. 15, n. 7, p. 314, doi. 10.1089/adt.2017.802
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C-assisted metabolomics analysis reveals the positive correlation between specific erythromycin production rate and intracellular propionyl-CoA pool size in Saccharopolyspora erythraea.
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- Bioprocess & Biosystems Engineering, 2017, v. 40, n. 9, p. 1337, doi. 10.1007/s00449-017-1792-0
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Acetyl-CoA synthetases of Saccharopolyspora erythraea are regulated by the nitrogen response regulator GlnR at both transcriptional and post-translational levels.
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- Molecular Microbiology, 2017, v. 103, n. 5, p. 845, doi. 10.1111/mmi.13595
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- Article
Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea.
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- Bioprocess & Biosystems Engineering, 2017, v. 40, n. 2, p. 201, doi. 10.1007/s00449-016-1687-5
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Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea.
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- Microbial Cell Factories, 2016, v. 15, p. 1, doi. 10.1186/s12934-016-0496-5
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In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2016, v. 100, n. 5, p. 2257, doi. 10.1007/s00253-015-7036-9
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Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis.
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- Applied Microbiology & Biotechnology, 2016, v. 100, n. 3, p. 1209, doi. 10.1007/s00253-015-6990-6
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DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2015, v. 99, n. 23, p. 10215, doi. 10.1007/s00253-015-6892-7
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Site-specific recombination for cloning of large DNA fragments in vitro.
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- Engineering in Life Sciences, 2015, v. 15, n. 6, p. 655, doi. 10.1002/elsc.201400267
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Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method.
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- Applied Microbiology & Biotechnology, 2015, v. 99, n. 6, p. 2683, doi. 10.1007/s00253-014-6255-9
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Lysine acetylproteome analysis suggests its roles in primary and secondary metabolism in Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2015, v. 99, n. 3, p. 1399, doi. 10.1007/s00253-014-6144-2
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The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m fermenter.
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- Bioprocess & Biosystems Engineering, 2015, v. 38, n. 1, p. 105, doi. 10.1007/s00449-014-1248-8
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Asymmetric Stetter reactions catalyzed by thiamine diphosphate-dependent enzymes.
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- Applied Microbiology & Biotechnology, 2014, v. 98, n. 23, p. 9681, doi. 10.1007/s00253-014-5850-0
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Three genes encoding citrate synthases in S accharopolyspora erythraea are regulated by the global nutrient-sensing regulators GlnR, DasR, and CRP.
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- Molecular Microbiology, 2014, v. 94, n. 5, p. 1065, doi. 10.1111/mmi.12818
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GlnR-mediated regulation of nitrogen metabolism in the actinomycete Saccharopolyspora erythraea.
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- Applied Microbiology & Biotechnology, 2014, v. 98, n. 18, p. 7935, doi. 10.1007/s00253-014-5878-1
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Suitable extracellular oxidoreduction potential inhibit rex regulation and effect central carbon and energy metabolism in Saccharopolyspora spinosa.
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- Microbial Cell Factories, 2014, v. 13, n. 1, p. 1, doi. 10.1186/s12934-014-0098-z
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SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea.
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- Journal of Industrial Microbiology & Biotechnology, 2014, v. 41, n. 7, p. 1159, doi. 10.1007/s10295-014-1449-9
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SACE_0012, a TetR-Family Transcriptional Regulator, Affects the Morphogenesis of Saccharopolyspora erythraea.
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- Current Microbiology, 2013, v. 67, n. 6, p. 647, doi. 10.1007/s00284-013-0410-x
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Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach.
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- BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-699
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Prediction and Characterization of Small Non-Coding RNAs Related to Secondary Metabolites in <i>Saccharopolyspora erythraea</i>.
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- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080676
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Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch.
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- BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-15
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Biochemical parameters of Saccharopolyspora Erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase.
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- Applied Biochemistry & Microbiology, 2013, v. 49, n. 2, p. 169, doi. 10.1134/S0003683813020166
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SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea.
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- Microbial Cell Factories, 2013, v. 12, n. 1, p. 3, doi. 10.1186/1475-2859-12-126
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Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production.
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- Antonie van Leeuwenhoek, 2012, v. 102, n. 3, p. 493, doi. 10.1007/s10482-012-9783-2
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