Works matching DE "RUNX proteins"

Results: 859

Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 4967, doi. 10.3390/ijms26114967

By:

Takemoto, Masahiro;
Sugishita, Yodo;
Takahashi-Suzuki, Yuki;
Fujiya, Hiroto;
Niki, Hisateru;
Yudoh, Kazuo

Publication type:

Article

Dexamethasone-boosted mesenchymal stem cell secretome: insight into hepatic protection.

Published in:

BMC Biotechnology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12896-025-00980-8

By:

Adly, Eiman M.;
Diab, Thoria;
Hessien, Mohamed

Publication type:

Article

PRMT1 inhibition enhances the cardioprotective effect of adipose-derived mesenchymal stem cells against myocardial infarction through RUNX1.

Published in:

Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04409-z

By:

Du, Dongdong;
Wang, Ting;
Sun, Yaodong;
Zhang, Yi;
Zhang, Bufan;
Shao, Jingrong;
Yang, Mengxue;
Huang, Chuan;
Zuo, Shengkai;
Wu, Naishi

Publication type:

Article

Icariin-loaded composite scaffold promotes osteogenic differentiation and bone regeneration.

Published in:

BMC Musculoskeletal Disorders, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12891-025-08824-4

By:

Jin, Dong-Sheng;
Zhao, Zhang-Hong;
Ruan, Shi-Qiang;
Huang, Wen-Liang;
Tian, Ren-Yuan;
Wan, Yu;
Deng, Jiang

Publication type:

Article

RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00426-z

By:

Hallett, Shawn A.;
Dixon, Ashley;
Marrale, Isabella;
Batoon, Lena;
Brenes, José;
Zhou, Annabelle;
Arbiv, Ariel;
Kaartinen, Vesa;
Allen, Benjamin;
Ono, Wanida;
Franceschi, Renny T.;
Ono, Noriaki

Publication type:

Article

Investigating the Associations Between Hmga2 Overexpression, R-Loop Reduction, and Bone Loss in Aging Mice.

Published in:

Medicina (1010660X), 2025, v. 61, n. 5, p. 820, doi. 10.3390/medicina61050820

By:

Cao, Yangyang;
Wang, Yantong;
Xia, Dengsheng

Publication type:

Article

Targeting casein kinase 2 and ubiquitin-specific protease 7 to modulate RUNX2-mediated osteogenesis in chronic kidney disease.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01222-5

By:

Lan, Haifeng;
Yu, Xiao-Jun;
Ling, Guangsheng;
Zeng, Yuwei;
Yang, Yixi;
He, Meiyang;
Yu, Yixiao;
Shao, Ming

Publication type:

Article

RUNX1 is a key inducer of human hematopoiesis controlling non-hematopoietic mesodermal development.

Published in:

Stem Cells, 2025, v. 43, n. 5, p. 1, doi. 10.1093/stmcls/sxaf019

By:

Shah, Zahir;
Wang, Cuihua;
Ullah, Hanif;
You, Hao;
Philonenko, Elena S;
Regan, Olga V;
Volchkov, Pavel;
Dai, Yong;
Yu, Jianhua;
Samokhvalov, Igor M

Publication type:

Article

The interaction between RUNX2 and core binding factor beta as a potential therapeutic target in canine osteosarcoma.

Published in:

Veterinary & Comparative Oncology, 2020, v. 18, n. 1, p. 52, doi. 10.1111/vco.12526

By:

Alegre, Fernando;
Ormonde, Amanda R.;
Godinez, Dayn R.;
Illendula, Anuradha;
Bushweller, John H.;
Wittenburg, Luke A.

Publication type:

Article

DNA Alkylation of the RUNX‐Binding Sequence by CBI–PI Polyamide Conjugates**.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 64, p. 14639, doi. 10.1002/chem.202002166

By:

Maeda, Rina;
Ito, Shinji;
Hashiya, Kaori;
Bando, Toshikazu;
Sugiyama, Hiroshi

Publication type:

Article

Taurine promotes human mesenchymal stem cells to differentiate into osteoblast through the ERK pathway.

Published in:

Amino Acids, 2014, v. 46, n. 7, p. 1673, doi. 10.1007/s00726-014-1729-8

By:

Zhou, Chenhui;
Zhang, Xue;
Xu, Liangliang;
Wu, Tie;
Cui, Liao;
Xu, Daohua

Publication type:

Article

Runx1 up-regulates chondrocyte to osteoblast lineage commitment and promotes bone formation by enhancing both chondrogenesis and osteogenesis.

Published in:

Biochemical Journal, 2020, v. 477, n. 13, p. 2421, doi. 10.1042/BCJ20200036

By:

Chen-Yi Tang;
Wei Chen;
Yuan Luo;
Jinjin Wu;
Yan Zhang;
Abigail McVicar;
Matthew McConnell;
Yuehua Liu;
Hou-De Zhou;
Yi-Ping Li

Publication type:

Article

Cell-microsphere based living microhybrids for osteogenesis regulating to boosting biomineralization.

Published in:

Regenerative Biomaterials, 2024, v. 11, p. 1, doi. 10.1093/rb/rbae125

By:

Hu, Zhaofan;
Zhang, Yunyang;
Zhang, Jingjing;
Zheng, Ran;
Yang, Yang;
Kong, Fei;
Li, Haoran;
Yang, Xinyan;
Yang, Shuhui;
Kong, Xiangdong;
Zhao, Ruibo

Publication type:

Article

Controlled-Release Hydrogel Microspheres to Deliver Multipotent Stem Cells for Treatment of Knee Osteoarthritis.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 11, p. 1315, doi. 10.3390/bioengineering10111315

By:

Hamilton, Megan;
Wang, Jinxi;
Dhar, Prajnaparamita;
Stehno-Bittel, Lisa

Publication type:

Article

Bioactive Scaffold Fabricated by 3D Printing for Enhancing Osteoporotic Bone Regeneration.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 10, p. N.PAG, doi. 10.3390/bioengineering9100525

By:

Zhang, Xiaoting;
Wang, Xinluan;
Lee, Yuk-wai;
Feng, Lu;
Wang, Bin;
Pan, Qi;
Meng, Xiangbo;
Cao, Huijuan;
Li, Linlong;
Wang, Haixing;
Bai, Shanshan;
Kong, Lingchi;
Chow, Dick Ho Kiu;
Qin, Ling;
Cui, Liao;
Lin, Sien;
Li, Gang

Publication type:

Article

18F–Choline PET/CT Identifies High-Grade Prostate Cancer Lesions Expressing Bone Biomarkers.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1657, doi. 10.3390/jcm8101657

By:

Urbano, Nicoletta;
Scimeca, Manuel;
Crocco, Antonio;
Mauriello, Alessandro;
Bonanno, Elena;
Schillaci, Orazio

Publication type:

Article

Stimulation of Human Osteoblast Differentiation in Magneto-Mechanically Actuated Ferromagnetic Fiber Networks.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1522, doi. 10.3390/jcm8101522

By:

Katarivas Levy, Galit;
Birch, Mark A.;
Brooks, Roger A.;
Neelakantan, Suresh;
Markaki, Athina E.

Publication type:

Article

Anti-Osteoporotic Effects of the Herbal Mixture of Cornus officinalis and Achyranthes japonica In Vitro and In Vivo.

Published in:

Plants (2223-7747), 2020, v. 9, n. 9, p. 1114, doi. 10.3390/plants9091114

By:

Park, Eunkuk;
Lee, Chang Gun;
Kim, Jeonghyun;
Lim, Eunguk;
Hwang, Seokjin;
Yun, Seung Hee;
Yong, Yoonjoong;
Jeong, Hyesoo;
Kim, Ji Ae;
Jin, Hyun-Seok;
Jeong, Seon-Yong

Publication type:

Article

Berberine Chloride and Hyperthermia Promote Osterix Expression and Suppress Cell Cycle Genes in Osteosarcoma Cells.

Published in:

Yemeni Journal for Medical Sciences, 2018, v. 12, n. 1, p. 37, doi. 10.20428/yjms.12.1.7

By:

Nashiry, Mohammed;
Al-Khateeb, Alyaa;
Froemming, Gabriele

Publication type:

Article

New Insights on the Therapeutic Potential of Runt-Related Transcription Factor 2 for Osteoarthritis: Evidence from Mendelian Randomization.

Published in:

Rheumatology & Therapy, 2024, v. 11, n. 4, p. 1001, doi. 10.1007/s40744-024-00682-1

By:

Xie, Jiale;
Xu, Xin;
Yang, Mingyi;
Yu, Hui;
Hao, Jinrong;
Yang, Dinglong;
Xu, Peng

Publication type:

Article

Significance of Runt-related transcription factor 1 and Notch1 expression in non-small-cell lung cancer: involvement in epithelial-mesenchymal transition and epidermal growth factor receptor-tyrosine kinase inhibitor therapy resistance.

Published in:

Egyptian Journal of Chest Diseases & Tuberculosis, 2024, v. 73, n. 3, p. 290, doi. 10.4103/ecdt.ecdt_95_23

By:

Rashad, Heba M.;
Ahmed, Hanan;
Mohamed, Samar N.;
Eleleimy, Hiam A.;
Abdel-Aal, Ebtehal M.

Publication type:

Article

Coexistence of acute myeloid leukemia with a complex chromosomal translocation and monoclonal gammopathy of undetermined significance: A case report and literature review.

Published in:

2025

By:

Qiao, Xue;
Geng, Li;
Tian, Tian;
Zhang, Jingnan;
Guo, Xiaonan;
Qiao, Shukai

Publication type:

Case Study

Role of RUNX2 in breast cancer development and drug resistance (Review).

Published in:

Oncology Letters, 2023, v. 25, n. 5, p. N.PAG, doi. 10.3892/ol.2023.13762

By:

Si, Wentao;
Kan, Chen;
Zhang, Leisheng;
Li, Feifei

Publication type:

Article

Mutational analysis of extranodal marginal zone lymphoma using next generation sequencing.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12068

By:

SEOK JAE HUH;
SUNG YONG OH;
SUEE LEE;
JI HYUN LEE;
SUNG HYUN KIM;
MIN KYUNG PAK;
HYO-JIN KIM

Publication type:

Article

Transcriptome changes induced by RUNX3 in cervical cancer cells in vitro.

Published in:

Oncology Letters, 2020, v. 19, n. 1, p. 651, doi. 10.3892/ol.2019.11128

By:

Gao, Qian-Qian;
Zhou, Bin;
Yu, Xiu-Zhang;
Zhang, Zhu;
Wang, Yan-Yun;
Song, Ya-Ping;
Zhang, Lin;
Luo, Hong;
Xi, Ming-Rong

Publication type:

Article

Gene expression of ASNS, LGMN and CTSB is elevated in a subgroup of childhood BCP-ALL with PAX5 deletion.

Published in:

Oncology Letters, 2019, v. 18, n. 6, p. 6926, doi. 10.3892/ol.2019.11046

By:

Wrona, Ewa;
Jakubowska, Justyna;
Pawlik, Bartłomiej;
Pastorczak, Agata;
Madzio, Joanna;
Lejman, Monika;
Sędek, Łukasz;
Kowalczyk, Jerzy;
Szczepański, Tomasz;
Młynarski, Wojciech

Publication type:

Article

Long non-coding RNA heart and neural crest derivatives expressed 2-antisense RNA 1 overexpression inhibits the proliferation of cancer cells by reducing RUNX2 expression in triple-negative breast cancer.

Published in:

Oncology Letters, 2019, v. 18, n. 6, p. 6775, doi. 10.3892/ol.2019.11001

By:

Wei, Min;
Liu, Lei;
Wang, Zhiwei

Publication type:

Article

High expression of microRNA-500 is associated with poor prognosis in patients with acute myeloid leukemia receiving allogeneic hematopoietic stem cell transplantation.

Published in:

Oncology Letters, 2019, v. 17, n. 6, p. 5815

By:

Zhang, Gaoqi;
Shi, Jinlong;
Yang, Xinrui;
Zhang, Xinpei;
Zhang, Lingxiu;
Zhang, Jilei;
Yang, Siyuan;
Wang, Jing;
Hu, Kai;
Ke, Xiaoyan;
Fu, Lin

Publication type:

Article

miR-205 targets runt-related transcription factor 2 to inhibit human pancreatic cancer progression.

Published in:

Oncology Letters, 2019, v. 17, n. 1, p. 843

By:

Zhuang, Lu;
Guo, Jia;
Yao, Yao;
Li, Zhaoshen

Publication type:

Article

The roles of RUNX3 in cervical cancer cells in vitro.

Published in:

Oncology Letters, 2018, v. 15, n. 6, p. 8729, doi. 10.3892/ol.2018.8419

By:

Li, ZhEN;
Fan, Pan;
DENg, Min;
ZENg, Chao

Publication type:

Article

Oncogenic role of microRNA-532-5p in human colorectal cancer via targeting of the 5'UTR of RUNX3.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 7215, doi. 10.3892/ol.2018.8217

By:

Zhang, Jiantao;
Zhou, Wenli;
Liu, Yanyan;
Liu, Tao;
Li, Chenyao;
Wang, Lei

Publication type:

Article

Expression levels of the runt-related transcription factor 1 and 3 genes in the development of acute myeloid leukemia.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 6733, doi. 10.3892/ol.2018.8143

By:

Krygier, Adrian;
Szmajda, Dagmara;
Żebrowska, Marta;
Jeleń, Agnieszka;
Balcerczak, Ewa

Publication type:

Article

A high-calcium environment induced ectopic calcification of renal interstitial fibroblasts via TFPI-2-DCHS1-ALP/ENPP1 axis to participate in Randall's plaque formation.

Published in:

Urolithiasis, 2024, v. 52, n. 1, p. 1, doi. 10.1007/s00240-024-01622-y

By:

Liu, Minghui;
Liu, Zhi;
Huang, Fang;
Chen, Hequn;
Yang, Zhongqing;
Zhu, Zewu

Publication type:

Article

A high-calcium environment induced ectopic calcification of renal interstitial fibroblasts via TFPI-2-DCHS1-ALP/ENPP1 axis to participate in Randall's plaque formation.

Published in:

Urolithiasis, 2024, v. 52, n. 1, p. 1, doi. 10.1007/s00240-024-01622-y

By:

Liu, Minghui;
Liu, Zhi;
Huang, Fang;
Chen, Hequn;
Yang, Zhongqing;
Zhu, Zewu

Publication type:

Article

Exploring the In Vitro Effects of Zingerone on Differentiation and Signalling Pathways in Bone Cell Lines.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 12, p. 693, doi. 10.3390/metabo14120693

By:

De Vos, Brunhildé;
Kasonga, Abe E.;
Joubert, Anna M.;
Nyakudya, Trevor T.

Publication type:

Article

Nϵ-Carboxymethyl-Lysine Deteriorates Vascular Calcification in Diabetic Atherosclerosis Induced by Vascular Smooth Muscle Cell-Derived Foam Cells.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00626

By:

Xu, Sui-Ning;
Zhou, Xin;
Zhu, Cun-Jun;
Qin, Wei;
Zhu, Jie;
Zhang, Ke-Lin;
Li, Hui-Jin;
Xing, Lu;
Lian, Kun;
Li, Cheng-Xiang;
Sun, Zhen;
Wang, Zhong-Qun;
Zhang, An-Ji;
Cao, Hui-Ling

Publication type:

Article

Fibromodulin – A New Target of Osteoarthritis Management?

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01475

By:

Li, Chenshuang;
Ha, Pin;
Jiang, Wenlu;
Haveles, Christos S.;
Zheng, Zhong;
Zou, Min

Publication type:

Article

Runx3 Mediates Resistance to Intracellular Bacterial Infection by Promoting IL12 Signaling in Group 1 ILC and NCR+ILC3.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.02101

By:

Shengxia Yin;
Jingjing Yu;
Bian Hu;
Chenyu Lu;
Xia Liu;
Xianzhi Gao;
Wei Li;
Lina Zhou;
Jianli Wang;
Di Wang;
Linrong Lu;
Lie Wang

Publication type:

Article

Pro-calcifying analysis of uraemic serum from patients treated with medium cut-off membrane in a prospective, cross-over study.

Published in:

Clinical Kidney Journal, 2021, v. 14, n. 7, p. 1798, doi. 10.1093/ckj/sfaa216

By:

Ciceri, Paola;
Tettamanti, Giorgia;
Galassi, Andrea;
Magagnoli, Lorenza;
Fabresse, Nicolas;
Alvarez, Jean-Claude;
Massy, Ziad A;
Messa, Piergiorgio;
Cozzolino, Mario

Publication type:

Article

Morphological and Molecular Analysis of Osteoblasts Differentiated from Mesenchymal Stem Cells in Polycaprolactone/Magnesium Oxide/Graphene Oxide Scaffold.

Published in:

International Journal of Organ Transplantation Medicine, 2019, v. 10, n. 4, p. 171

By:

Niknam, Z.;
Zali, H.;
Mansouri, V.;
Tavirani, M. Rezaei;
Omidi, M.

Publication type:

Article

Positive Association of Leptin and Artery Calcification of Lower Extremity in Patients With Type 2 Diabetes Mellitus: A Pilot Study.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.583575

By:

Chai, SanBao;
Chen, Yao;
Xin, SiXu;
Yuan, Ning;
Liu, YuFang;
Sun, JianBin;
Meng, XiangYu;
Qi, YongFen

Publication type:

Article

Effect of Diabetes Mellitus on Implant Osseointegration of Titanium Screws: An Animal Experimental Study.

Published in:

Orthopaedic Surgery, 2022, v. 14, n. 6, p. 1217, doi. 10.1111/os.13274

By:

Xiao, Lei;
Zhou, Yi‐juan;
Jiang, Ya‐bin;
Tam, Man Seng;
Cheang, Lek Hang;
Wang, Hua‐jun;
Zha, Zhen‐gang;
Zheng, Xiao‐fei

Publication type:

Article

Bindarit Reduces Bone Loss in Ovariectomized Mice by Inhibiting CCL2 and CCL7 Expression via the NF‐κB Signaling Pathway.

Published in:

Orthopaedic Surgery, 2022, v. 14, n. 6, p. 1203, doi. 10.1111/os.13252

By:

Yuan, Shi‐guo;
Hu, Hong‐ling;
Wang, Xin‐jia;
Yang, Jin‐cheng;
Zhou, Rong‐ping;
Bai, Xiao‐chun;
Lai, Ping‐lin

Publication type:

Article

Functions of Exogenous RUNX2 in Giant Cell Tumor of Bone In Vitro.

Published in:

Orthopaedic Surgery, 2020, v. 12, n. 2, p. 668, doi. 10.1111/os.12568

By:

Jin, Yuan‐han;
Zhang, Jing;
Zhu, Hao;
Fan, Gen‐tao;
Zhou, Guang‐xin

Publication type:

Article

MiRNAs Expression Modulates Osteogenesis in Response to Exercise and Nutrition.

Published in:

Genes, 2023, v. 14, n. 9, p. 1667, doi. 10.3390/genes14091667

By:

Proia, Patrizia;
Rossi, Carlo;
Alioto, Anna;
Amato, Alessandra;
Polizzotto, Caterina;
Pagliaro, Andrea;
Kuliś, Szymon;
Baldassano, Sara

Publication type:

Article

Methylation of RUNX3 Promoter 2 in the Whole Blood of Children with Ulcerative Colitis.

Published in:

Genes, 2022, v. 13, n. 9, p. 1568, doi. 10.3390/genes13091568

By:

Dybska, Emilia;
Nowak, Jan Krzysztof;
Banaszkiewicz, Aleksandra;
Szaflarska-Popławska, Anna;
Kierkuś, Jarosław;
Kwiecień, Jarosław;
Grzybowska-Chlebowczyk, Urszula;
Walkowiak, Jarosław

Publication type:

Article

A Novel 90-kbp Deletion of RUNX2 Associated with Cleidocranial Dysplasia.

Published in:

Genes, 2022, v. 13, n. 7, p. 1128, doi. 10.3390/genes13071128

By:

Zhang, Yanli;
Duan, Xiaohong

Publication type:

Article

Activation of Steroidogenesis, Anti-Apoptotic Activity, and Proliferation in Porcine Granulosa Cells by RUNX1 Is Negatively Regulated by H3K27me3 Transcriptional Repression.

Published in:

Genes, 2020, v. 11, n. 5, p. 495, doi. 10.3390/genes11050495

By:

Zhong, Yuyi;
Li, Liying;
He, Yingting;
He, Bo;
Li, Zhonghui;
Zhang, Zhe;
Zhang, Hao;
Yuan, Xiaolong;
Li, Jiaqi

Publication type:

Article

E26 transformation-specific 1 is implicated in the inhibition of osteogenic differentiation induced by chronic high glucose by directly regulating Runx2 expression.

Published in:

Journal of Biomedical Research, 2022, v. 36, n. 1, p. 39, doi. 10.7555/JBR.35.20210123

By:

Wenqian Xia;
Xiao Han;
Lin Wang

Publication type:

Article

Knockdown of circ_0000512 Inhibits Cell Proliferation and Promotes Apoptosis in Colorectal Cancer by Regulating miR-296-5p/RUNX1 Axis.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 7357, doi. 10.2147/OTT.S250495

By:

Wang, Lihong;
Wu, Huili;
Chu, Feifei;
Zhang, Li;
Xiao, Xingguo

Publication type:

Article