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Characteristic effect of hydroxyurea on the higher-order structure of DNA and gene expression.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-64538-y
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- Article
Hydration of N -Hydroxyurea from Ab Initio Molecular Dynamics Simulations.
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- Molecules, 2024, v. 29, n. 11, p. 2435, doi. 10.3390/molecules29112435
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- Article
Leucoma salicis nucleopolyhedrovirus (LesaNPV) genome sequence shed new light on the origin of the Alphabaculovirus orpseudotsugatae species.
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- Virus Genes, 2024, v. 60, n. 3, p. 275, doi. 10.1007/s11262-024-02062-x
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- Article
The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48076-9
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- Article
IGF2BP3 regulates the expression of RRM2 and promotes the progression of rheumatoid arthritis via RRM2/Akt/MMP-9 pathway.
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- PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0303593
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- Article
Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability.
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- PLoS Genetics, 2024, v. 20, n. 5, p. 1, doi. 10.1371/journal.pgen.1011148
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- Article
Meat Characteristics, Expression of Myosin Heavy Chain and Metabolism-Related Genes in Thai Native Pigs.
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- Foods, 2024, v. 13, n. 10, p. 1502, doi. 10.3390/foods13101502
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- Article
Nitrogen-Centered Radicals Derived from Azidonucleosides.
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- Molecules, 2024, v. 29, n. 10, p. 2310, doi. 10.3390/molecules29102310
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- Article
Machine learning and weighted gene co-expression network analysis identify a three-gene signature to diagnose rheumatoid arthritis.
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- Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1387311
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Vanillin production by Corynebacterium glutamicum using heterologous aromatic carboxylic acid reductases.
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- Biotechnology for Biofuels & Bioproducts, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13068-024-02507-3
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- Article
Ribonucleotide reductase inhibition improves the symptoms of a Caenorhabditis elegans model of Alzheimer's disease.
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- G3: Genes | Genomes | Genetics, 2024, v. 14, n. 5, p. 1, doi. 10.1093/g3journal/jkae040
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- Article
Detection of ribonucleotides embedded in DNA by Nanopore sequencing.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06077-w
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A comprehensive analysis of ribonucleotide reductase subunit M2 for carcinogenesis in pan-cancer.
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- PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0299949
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- Article
ROS-sensitive selenium-containing cationic brush polymer with potent gene transfection efficiency and biocompatibility.
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- Journal of Applied Polymer Science, 2024, v. 141, n. 14, p. 1, doi. 10.1002/app.55199
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- Article
Synergistic Effect of a Combination of Proteasome and Ribonucleotide Reductase Inhibitors in a Biochemical Model of the Yeast Saccharomyces cerevisiae and a Glioblastoma Cell Line.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3977, doi. 10.3390/ijms25073977
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- Article
RTF2 controls replication repriming and ribonucleotide excision at the replisome.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45947-z
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- Article
Prognostic value of RRM1 and its effect on chemoresistance in pancreatic cancer.
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- Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 3, p. 237, doi. 10.1007/s00280-023-04616-6
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- Article
N6-methyladenosine facilitates mitochondrial fusion of colorectal cancer cells via induction of GSH synthesis and stabilization of OPA1 mRNA.
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- National Science Review, 2024, v. 11, n. 3, p. 1, doi. 10.1093/nsr/nwae039
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- Article
Effective engineering of a ketoreductase for the biocatalytic synthesis of an ipatasertib precursor.
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- Communications Chemistry, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42004-024-01130-5
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- Article
Glutathione Reductase Expression and Its Prognostic Significance in Colon Cancer.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1097, doi. 10.3390/ijms25021097
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- Article
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02911-x
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Mapping combinatorial drug effects to DNA damage response kinase inhibitors.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-44108-y
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- Article
Iron necessity for chlamydospore germination in Fusarium oxysporum f. sp. cubense TR4.
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- BioMetals, 2023, v. 36, n. 6, p. 1295, doi. 10.1007/s10534-023-00519-4
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- Article
The Marine Natural Compound Dragmacidin D Selectively Induces Apoptosis in Triple-Negative Breast Cancer Spheroids.
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- Marine Drugs, 2023, v. 21, n. 12, p. 642, doi. 10.3390/md21120642
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- Article
A PCR-Based Survey of Methane-Cycling Archaea in Methane-Soaked Subsurface Sediments of Guaymas Basin, Gulf of California.
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- Microorganisms, 2023, v. 11, n. 12, p. 2956, doi. 10.3390/microorganisms11122956
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- Article
One-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, contributing to tumor suppression.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38142-5
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- Article
Impact of N221S missense mutation in human ribonucleotide reductase small subunit b on mitochondrial DNA depletion syndrome.
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- Scientific Reports, 2023, p. 1, doi. 10.1038/s41598-023-47284-5
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- Article
Prolinyl Nucleotides Drive Enzyme‐Free Genetic Copying of RNA.
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- Angewandte Chemie, 2023, v. 135, n. 41, p. 1, doi. 10.1002/ange.202307591
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- Article
RRM2 as a novel prognostic and therapeutic target of NF1-associated MPNST.
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- Cellular Oncology (2211-3428), 2023, v. 46, n. 5, p. 1399, doi. 10.1007/s13402-023-00819-4
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- Article
Serum ribonucleotide reductase M2 is a potential biomarker for diagnosing and monitoring liver fibrosis in chronic hepatitis B patients.
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- Journal of Medical Virology, 2023, v. 95, n. 10, p. 1, doi. 10.1002/jmv.29157
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- Article
Pangenomic Analysis of Nucleo-Cytoplasmic Large DNA Viruses. I: The Phylogenetic Distribution of Conserved Oxygen-Dependent Enzymes Reveals a Capture-Gene Process.
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- Journal of Molecular Evolution, 2023, v. 91, n. 5, p. 647, doi. 10.1007/s00239-023-10126-z
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- Article
RRM2‑mediated Wnt/β‑catenin signaling pathway activation in lung adenocarcinoma: A potential prognostic biomarker.
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- Oncology Letters, 2023, v. 26, n. 4, p. N.PAG, doi. 10.3892/ol.2023.14003
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- Article
Ribonucleotide reductase regulatory subunit M2 (RRM2) as a potential sero-diagnostic biomarker in non-small cell lung cancer.
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- PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0291461
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Exploration of the potential common pathogenic mechanisms in COVID-19 and silicosis by using bioinformatics and system biology.
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- Functional & Integrative Genomics, 2023, v. 23, n. 3, p. 1, doi. 10.1007/s10142-023-01092-2
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- Article
Synergistic anticancer activity of combined ATR and ribonucleotide reductase inhibition in Ewing's sarcoma cells.
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- Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 11, p. 8605, doi. 10.1007/s00432-023-04804-0
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- Article
Open Questions about the Roles of DnaA, Related Proteins, and Hyperstructure Dynamics in the Cell Cycle.
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- Life (2075-1729), 2023, v. 13, n. 9, p. 1890, doi. 10.3390/life13091890
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- Article
Mineral-Mediated Oligoribonucleotide Condensation: Broadening the Scope of Prebiotic Possibilities on the Early Earth.
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- Life (2075-1729), 2023, v. 13, n. 9, p. 1899, doi. 10.3390/life13091899
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- Article
One-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, contributing to tumor suppression.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38142-5
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- Publication type:
- Article
Maize LOST SUBSIDIARY CELL encoding a large subunit of ribonucleotide reductase is required for subsidiary cell development and plant growth.
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- Journal of Experimental Botany, 2023, v. 74, n. 15, p. 4449, doi. 10.1093/jxb/erad153
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- Article
Circ_0006646 Accelerates the Growth and Metastasis of Cervical Cancer by Elevating RRM2 Through miR-758-3p.
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- Biochemical Genetics, 2023, v. 61, n. 4, p. 1300, doi. 10.1007/s10528-022-10320-6
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- Article
Vitamin B 12 Auxotrophy in Isolates from the Deep Subsurface of the Iberian Pyrite Belt.
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- Genes, 2023, v. 14, n. 7, p. 1339, doi. 10.3390/genes14071339
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- Article
Hepatitis C Virus Down-Regulates the Expression of Ribonucleotide Reductases to Promote Its Replication.
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- Pathogens, 2023, v. 12, n. 7, p. 892, doi. 10.3390/pathogens12070892
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- Article
COORDINATION BEHAVIOUR AND COMPUTATIONAL STUDIES OF 3-FORMYL CHROMONE N(4)-METHYL-N(4)-PHENYLTHIOSEMICARBAZONE AND ITS TRANSITION METAL COMPLEXES.
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- Rasayan Journal of Chemistry, 2023, v. 16, n. 3, p. 1435, doi. 10.31788/RJC.2023.1638352
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- Article
Potential Role of Ribonucleotide Reductase Enzyme in Mitochondria Function and Woody Breast Condition in Broiler Chickens.
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- Animals (2076-2615), 2023, v. 13, n. 12, p. 2038, doi. 10.3390/ani13122038
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- Article
C11orf54 promotes DNA repair via blocking CMA-mediated degradation of HIF1A.
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- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04957-1
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- Article
The Warburg effect modulates DHODH role in ferroptosis: a review.
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- Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-022-01025-9
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- Article
The identification of viral ribonucleotide reductase encoded by ORF23 and ORF141 genes and effect on CyHV-2 replication.
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- Frontiers in Microbiology, 2023, p. 1, doi. 10.3389/fmicb.2023.1154840
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- Article
Protein-Sparing Effect of α-Lipoic Acid in Diets with Different Protein/Carbohydrate Ratios for the Oriental River Prawn, Macrobrachium nipponense.
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- Aquaculture Research, 2023, p. 1, doi. 10.1155/2023/5614359
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- Article
Characterisation of an Escherichia coli line that completely lacks ribonucleotide reduction yields insights into the evolution of parasitism and endosymbiosis.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.83845
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- Article
Over-expression of RRM2 predicts adverse prognosis correlated with immune infiltrates: A potential biomarker for hepatocellular carcinoma.
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- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1144269
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- Article