Works matching DE "REGORAFENIB"

Results: 476

Study of genetic polymorphisms and steady-state trough concentrations of imatinib and its active metabolite in predicting efficacy in gastrointestinal stromal tumors.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1604619

By:

Zhang, Menghua;
Chen, Zhiyao;
Liu, Xiaoxue;
Zhou, Xiaojun;
Miao, Liyan

Publication type:

Article

Safety and Efficacy of Regorafenib and 5-Fluorouracil Combination Therapy in Refractory Metastatic Colorectal Cancer After Third-Line Treatment: An Institutional Experience.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1151, doi. 10.3390/biomedicines13051151

By:

Abdelrahim, Maen;
Esmail, Abdullah;
Al-Najjar, Ebtesam;
Khasawneh, Bayan;
Umoru, Godsfavour;
Abdelrahim, Waseem;
Abboud, Karen;
Ajewole, Veronica B.

Publication type:

Article

Sorafenib-Regorafenib Sequential Therapy in Advanced Hepatocellular Carcinoma: A Single-Institute Experience.

Published in:

Digestive Diseases, 2017, v. 35, n. 6, p. 611, doi. 10.1159/000480257

By:

Kazuomi Ueshima;
Naoshi Nishida;
Masatoshi Kudo

Publication type:

Article

Regorafenib CSF Penetration, Efficacy, and MRI Patterns in Recurrent Malignant Glioma Patients.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 12, p. 2031, doi. 10.3390/jcm8122031

By:

Zeiner, Pia S.;
Kinzig, Martina;
Divé, Iris;
Maurer, Gabriele D.;
Filipski, Katharina;
Harter, Patrick N.;
Senft, Christian;
Bähr, Oliver;
Hattingen, Elke;
Steinbach, Joachim P.;
Sörgel, Fritz;
Voss, Martin;
Steidl, Eike;
Ronellenfitsch, Michael W.

Publication type:

Article

Expression of PD-1 and CTLA-4 Are Negative Prognostic Markers in Renal Cell Carcinoma.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 743, doi. 10.3390/jcm8050743

By:

Kahlmeyer, Andreas;
Stöhr, Christine G.;
Hartmann, Arndt;
Goebell, Peter J.;
Wullich, Bernd;
Wach, Sven;
Taubert, Helge;
Erlmeier, Franziska

Publication type:

Article

PD‐1 inhibitors in metastatic colorectal cancer.

Published in:

ANZ Journal of Surgery, 2021, v. 91, n. 12, p. E758, doi. 10.1111/ans.16878

By:

Henry, Luke;
Nguyen, Nicholas;
Asokan, Gayatri;
Hoh, Su Mei;
Gandhi, Jamish

Publication type:

Article

Regorafenib plus programmed death‑1 inhibitors vs. regorafenib monotherapy in second‑line treatment for advanced hepatocellular carcinoma: A systematic review and meta‑analysis.

Published in:

Oncology Letters, 2024, v. 28, n. 1, p. N.PAG, doi. 10.3892/ol.2024.14451

By:

Li, Zhao;
Wang, Jie;
Zhao, Jingbing;
Leng, Zhengwei

Publication type:

Article

Effectiveness of immune checkpoint inhibitors in combination with tyrosine kinase inhibitors in patients with advanced or metastatic colorectal carcinoma with either mismatch repair proficient or metastatic microsatellite stable disease: A systematic review and meta‑analysis

Published in:

Oncology Letters, 2024, v. 27, n. 4, p. N.PAG, doi. 10.3892/ol.2024.14286

By:

Li, Ji;
Zhu, Jin-Xian;
Zhang, Yu-Xin;
Li, Shi-Qiang

Publication type:

Article

Early low blood MALT1 expression levels forecast better efficacy of PD-1 inhibitor-based treatment in patients with metastatic colorectal cancer.

Published in:

Oncology Letters, 2023, v. 26, n. 2, p. 1, doi. 10.3892/ol.2023.13915

By:

CHUANMING LI;
FAN YU;
WANLI XU

Publication type:

Article

Expression of AMP-activated protein kinase/ten-eleven translocation 2 and their clinical relevance in colorectal cancer.

Published in:

Oncology Letters, 2021, v. 21, n. 2, p. 1, doi. 10.3892/ol.2021.12425

By:

DONG HYUN KANG;
DONG JUN JEONG;
TAE SUNG AHN;
HYUN YONG LEE;
HAN JO KIM;
SANG BYUNG BAE;
HYEONG JOO KIM;
MOON SOO LEE;
HYOG YOUNG KWON;
MOO-JUN BAEK

Publication type:

Article

TUFM-knockdown inhibits the migration and proliferation of gastrointestinal stromal tumor cells.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12113

By:

XIAOYUAN WENG;
SONG ZHENG;
HANLI SHUI;
GUOSHENG LIN;
YONGJIAN ZHOU

Publication type:

Article

Regorafenib treatment outcome for Taiwanese patients with metastatic gastrointestinal stromal tumors after failure of imatinib and sunitinib: A prospective, non-randomized, single-center study.

Published in:

Oncology Letters, 2020, v. 20, n. 3, p. 2131, doi. 10.3892/ol.2020.11756

By:

Hu, Chia-Hsiang;
Yeh, Chun-Nan;
Chen, Jen-Shi;
Tsai, Chun-Yi;
Wang, Shang-Yu;
Cheng, Chi-Tung;
Yeh, Ta-Sen

Publication type:

Article

Analysis of immune-related signatures of colorectal cancer identifying two different immune phenotypes: Evidence for immune checkpoint inhibitor therapy.

Published in:

Oncology Letters, 2020, v. 20, n. 1, p. 517, doi. 10.3892/ol.2020.11605

By:

Chen, Gang;
Wang, Lin;
Diao, Tongwei;
Chen, Ying;
Cao, Chengbo;
Zhang, Xindong

Publication type:

Article

MicroRNA-758 acts as a tumor inhibitor in colorectal cancer through targeting PAX6 and regulating PI3K/AKT pathway.

Published in:

Oncology Letters, 2020, v. 19, n. 6, p. 3923, doi. 10.3892/ol.2020.11516

By:

XINLI ZHANG;
JUMEI XU;
HONGCHANG ZHANG;
JILAN SUN;
NA LI;
XIANYU HUANG

Publication type:

Article

Retrospective study of regorafenib and trifluridine/tipiracil efficacy as a third-line or later chemotherapy regimen for refractory metastatic colorectal cancer.

Published in:

Oncology Letters, 2018, v. 16, n. 5, p. 6589, doi. 10.3892/ol.2018.9421

By:

Tanaka, Akira;
Sadahiro, Sotaro;
Suzuki, Toshiyuki;
Okada, Kazutake;
Saito, Gota;
Miyakita, Hiroshi

Publication type:

Article

Regorafenib diminishes the expression and secretion of angiogenesis and metastasis associated proteins and inhibits cell invasion via NF-κB inactivation in SK-Hep1 cells.

Published in:

Oncology Letters, 2017, v. 14, n. 1, p. 461, doi. 10.3892/ol.2017.6142

By:

YU‑CHANG LIU;
WEI‑SHU WANG;
RENG‑HONG WU

Publication type:

Article

Early tumor cavitation with regorafenib in metastatic colorectal cancer: A case report.

Published in:

2016

By:

KENTA KAWASAKI;
YASUO HAMAMOTO;
MASAYUKI ADACHI;
TAKANORI KANAI;
HIROMASA TAKAISHI

Publication type:

Case Study

Immunosuppressant therapy successfully improved regorafenib-induced severe hepatic injury in a patient with metastatic gastrointestinal stromal tumor: A case report.

Published in:

2016

By:

MIYUKI KUWAYAMA;
KEITA UCHINO;
KOTOE TAKAYOSHI;
MASATO KOMODA;
MOTOYUKI KOHJIMA;
MAKOTO NAKAMUTA;
SEIYA MOMOSAKI;
HITOSHI KUSABA;
KOICHI AKASHI;
EISHI BABA

Publication type:

Case Study

Clinical activity of regorafenib in elderly patients with recurrent glioblastoma.

Published in:

Molecular & Clinical Oncology, 2023, v. 18, n. 2, p. N.PAG, doi. 10.3892/mco.2023.2605

By:

Fasano, Morena;
Pirozzi, Mario;
Famiglietti, Vincenzo;
Facchini, Sergio;
Caterino, Marianna;
Caroprese, Mara;
Barillaro, Angela;
Di Giovanni, Ilaria;
Auriemma, Annunziata;
Ileana Sara Fattoruso, Silvia;
Somma, Teresa;
Solari, Domenico;
Bocchetti, Marco;
Conson, Manuel;
Pacelli, Roberto;
Ciardiello, Fortunato;
Addeo, Raffaele

Publication type:

Article

Complete response of MSI-high metastatic colon cancer following treatment with regorafenib: A case report.

Published in:

2021

By:

Baik, Hyungjoo;
Lee, Hee Ju;
Park, Jueun;
Park, Ha Young;
Park, Jinyoung;
Lee, Sunseong;
Bae, Ki Beom

Publication type:

Case Study

Treatment of metastatic refractory colorectal cancer following regorafenib failure.

Published in:

Molecular & Clinical Oncology, 2017, v. 7, n. 2, p. 308, doi. 10.3892/mco.2017.1307

By:

NOBUMICHI TAKEUCHI;
KUMIKO KOIKE;
SONOMI YOSHIDA;
AKIKO KUDO;
NODOKA SEKIGUCHI;
ATARU NAKAYAMA;
KOUJI KUBOTA;
TAKASHI ROKUHARA;
MASAYUKI KITAHARA

Publication type:

Article

Response to regorafenib at an initial dose of 120 mg as salvage therapy for metastatic colorectal cancer.

Published in:

Molecular & Clinical Oncology, 2017, v. 6, n. 3, p. 365, doi. 10.3892/mco.2017.1145

By:

HIROSHI OSAWA

Publication type:

Article

Pseudocirrhosis caused by regorafenib in an advanced rectal cancer patient with multiple liver metastases.

Published in:

Molecular & Clinical Oncology, 2017, v. 6, n. 1, p. 63, doi. 10.3892/mco.2016.1096

By:

KENSUKE KUMAMOTO;
SHUNGO ENDO;
NORIYUKI ISOHATA;
AZUMA NIREI;
DAIKI NEMOTO;
KENICHI UTANO;
TAKURO SAITO;
KAZUTOMO TOGASHI

Publication type:

Article

Computed tomograpy evaluation of morphological changes, clinical response and survival in colorectal cancer liver metastasis treated by regorafenib: A case report.

Published in:

2016

By:

NOBUHISA MATSUHASHI;
TAKAO TAKAHASHI;
JUNKO KATO;
TOSHIYUKI TANAHASHI;
SATOSHI MATSUI;
YOSHIYUKI SASAKI;
HISASHI IMAI;
YOSHIHIRO TANAKA;
NAOKI OKUMURA;
KAZUYA YAMAGUCHI;
MANABU FUTAMURA;
SHINJI OSADA;
KAZUHIRO YOSHIDA

Publication type:

Case Study

Comparison of cost-effectiveness of regorafenib and trifluridine/tipiracil combination tablet for treating advanced and recurrent colorectal cancer.

Published in:

Molecular & Clinical Oncology, 2016, v. 5, n. 5, p. 635, doi. 10.3892/mco.2016.1020

By:

MICHIO KIMURA;
EISEKI USAMI;
MINA IWAI;
MAKIKO GO;
HITOMI TERAMACHI;
TOMOAKI YOSHIMURA

Publication type:

Article

Discovery of Synergistic Drug Combinations for Colorectal Cancer Driven by Tumor Barcode Derived from Metabolomics "Big Data".

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 6, p. 494, doi. 10.3390/metabo12060494

By:

Lv, Bo;
Xu, Ruijie;
Xing, Xinrui;
Liao, Chuyao;
Zhang, Zunjian;
Zhang, Pei;
Xu, Fengguo

Publication type:

Article

Management of Regorafenib-Induced Hand-Foot Skin Reaction with Topical Chinese Medicine and Urea Ointment: A Case Report and Literature Review.

Published in:

OncoTargets & Therapy, 2025, v. 18, p. 509, doi. 10.2147/OTT.S510766

By:

Liu, Zhe-Ning;
Shen, Yu-Lei;
Dong, Hui-Jing;
Tan, Ke-Xin;
Li, Jia;
Peng, Yan-Mei;
Cui, Hui-Juan

Publication type:

Article

The Roles of Serum CXCL16 in Circulating Tregs and Gastrointestinal Stromal Tumor Cells [Retraction].

Published in:

2023

By:

Xing, Ya-Nan;
Zhang, Jun-Yan;
Xu, Hui-Mian

Publication type:

Correction Notice

Efficacy and Safety of Regorafenib with or without PD-1 Inhibitors as Second-Line Therapy for Advanced Hepatocellular Carcinoma in Real-World Clinical Practice.

Published in:

OncoTargets & Therapy, 2022, v. 15, p. 1079, doi. 10.2147/OTT.S383685

By:

Liu, Kan;
Wu, Jianbing;
Xu, Yongkang;
Li, Dan;
Huang, Shenlang;
Mao, Ye

Publication type:

Article

Response of Scalp and Skull Metastasis to Anti-PD-1 Antibody Combined with Regorafenib Treatment in a Sorafenib-Resistant Hepatocellular Carcinoma Patient and a Literature Review.

Published in:

2022

By:

Long, Xin;
Zhang, Lei;
Wang, Wen-qiang;
Zhang, Er-lei;
Lv, Xing;
Huang, Zhi-yong

Publication type:

Case Study

microRNA-769 is Downregulated in Colorectal Cancer and Inhibits Cancer Progression by Directly Targeting Cyclin-Dependent Kinase 1 [Retraction].

Published in:

OncoTargets & Therapy, 2021, v. 14, p. 4851, doi. 10.2147/OTT.S339847

By:

Wang, Lei;
Xu, Minyi;
Lu, Pei;
Zhou, Fangfang

Publication type:

Article

Complete Response to the Sequential Treatment with Regorafenib Followed by PD-1 Inhibitor in a Sorafenib-Refractory Hepatocellular Carcinoma Patient.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 12477, doi. 10.2147/OTT.S284092

By:

Zhang, Er-lei;
Zhang, Zun-yi;
Li, Jian;
Huang, Zhi-yong

Publication type:

Article

Chloroquine Combined with Imatinib Overcomes Imatinib Resistance in Gastrointestinal Stromal Tumors by Inhibiting Autophagy via the MAPK/ERK Pathway.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 6433, doi. 10.2147/OTT.S256935

By:

Zheng, Song;
Shu, Yefei;
Lu, Yidan;
Sun, Yangcheng

Publication type:

Article

Adverse events risk associated with regorafenib in the treatment of advanced solid tumors: meta-analysis of randomized controlled trials.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 6405, doi. 10.2147/OTT.S156760

By:

Yin, Xiaonan;
Yin, Yuan;
Shen, Chaoyong;
Chen, Huijiao;
Wang, Jiang;
Cai, Zhaolun;
Chen, Zhixin;
Zhang, Bo

Publication type:

Article

Profile of trifluridine/tipiracil hydrochloride in the treatment of metastatic colorectal cancer: efficacy, safety, and place in therapy.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 4599, doi. 10.2147/OTT.S106101

By:

Yu Sunakawa;
Naoki Izawa;
Takuro Mizukami;
Yoshiki Horie;
Mami Hirakawa;
Hiroyuki Arai;
Takashi Ogura;
Takashi Tsuda;
Takako Eguchi Nakajima

Publication type:

Article

Targeting gastrointestinal stromal tumors: the role of regorafenib.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 3009, doi. 10.2147/OTT.S104081

By:

Schroeder, Brett;
Zula Li;
Cranmer, Lee D.;
Jones, Robin L.;
Pollack, Seth M.

Publication type:

Article

Molecular profiling in the treatment of colorectal cancer: focus on regorafenib.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 2949, doi. 10.2147/OTT.S79145

By:

Yiyi Yan;
Grothey, Axel

Publication type:

Article

FOLFIRI and regorafenib combination therapy with dose escalation of irinotecan as fourth-line treatment for patients with metastatic colon cancer according to UGT1A1 genotyping.

Published in:

OncoTargets & Therapy, 2014, v. 7, p. 2143, doi. 10.2147/OTT.S69774

By:

Chien-Yu Lu;
Yung-Sung Yeh;
Ching-Wen Huang;
Cheng-Jen Ma;
Fang-Jung Yu;
Jaw-Yuan Wang

Publication type:

Article

Regorafenib treatment for patients with hepatocellular carcinoma who progressed on sorafenib—A cost-effectiveness analysis.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0207132

By:

Shlomai, Amir;
Leshno, Moshe;
Goldstein, Daniel A.

Publication type:

Article

Efficacy and safety of raltitrexed plus S-1 versus regorafenib in patients with refractory metastatic colorectal cancer: a real-world propensity score matching study.

Published in:

Therapeutic Advances in Gastroenterology, 2022, v. 15, p. 1, doi. 10.1177/17562848221098246

By:

Zhou, Yu-Wen;
Wang, Jia-Ling;
Li, Qing-Fang;
He, Yuan-Lin;
Li, Lin-Juan;
Liu, Rui-Zhi;
Chen, Ye;
Zhang, Shuang;
Qiu, Meng;
Liu, Ji-Yan

Publication type:

Article

Experience with regorafenib in the treatment of hepatocellular carcinoma.

Published in:

Therapeutic Advances in Gastroenterology, 2021, v. 14, p. 1, doi. 10.1177/17562848211016959

By:

Granito, Alessandro;
Forgione, Antonella;
Marinelli, Sara;
Renzulli, Matteo;
Ielasi, Luca;
Sansone, Vito;
Benevento, Francesca;
Piscaglia, Fabio;
Tovoli, Francesco

Publication type:

Article

Experience with regorafenib in the treatment of hepatocellular carcinoma.

Published in:

Therapeutic Advances in Gastroenterology, 2021, v. 14, p. 1, doi. 10.1177/17562848211016959

By:

Granito, Alessandro;
Forgione, Antonella;
Marinelli, Sara;
Renzulli, Matteo;
Ielasi, Luca;
Sansone, Vito;
Benevento, Francesca;
Piscaglia, Fabio;
Tovoli, Francesco

Publication type:

Article

Complete radiological response to first-line regorafenib in a patient with abdominal relapse of BRAF V600E mutated GIST.

Published in:

Therapeutic Advances in Gastroenterology, 2020, v. 13, p. 1, doi. 10.1177/1756284820927305

By:

Nannini, Margherita;
Valerio, Di Scioscio;
Gruppioni, Elisa;
Altimari, Annalisa;
Chiusole, Benedetta;
Saponara, Maristella;
Pantaleo, Maria Abbondanza;
Brunello, Antonella

Publication type:

Article

Complete radiological response to first-line regorafenib in a patient with abdominal relapse of BRAF V600E mutated GIST.

Published in:

Therapeutic Advances in Gastroenterology, 2020, v. 13, p. 1, doi. 10.1177/1756284820927305

By:

Nannini, Margherita;
Valerio, Di Scioscio;
Gruppioni, Elisa;
Altimari, Annalisa;
Chiusole, Benedetta;
Saponara, Maristella;
Pantaleo, Maria Abbondanza;
Brunello, Antonella

Publication type:

Article

IMMUNOSTIMULATORY MONOCLONAL ANTIBODIES FOR HEPATOCELLULAR CARCINOMA THERAPY. TRENDS AND PERSPECTIVES.

Published in:

Medicina (Buenos Aires), 2018, v. 78, n. 1, p. 29

By:

MAZZOLINI, GUILLERMO D.;
MALVICINI, MARIANA

Publication type:

Article

Regorafenib in Advanced Colorectal Cancer.

Published in:

Cancer & Chemotherapy Reviews, 2017, v. 12, n. 1, p. 3

By:

García-Alfonso, Pilar;
Muñoz-Martín, Andrés;
Blanco-Codeisido, Montserrat;
Calvo-Ferrándiz, Aitana

Publication type:

Article

Regorafenib in the Management of Metastatic Colorectal Cancer.

Published in:

Cancer & Chemotherapy Reviews, 2014, v. 9, n. 1, p. 15

By:

Touchefeu, Yann;
Habes, Sarah;
Matysiak-Budnik, Tamara

Publication type:

Article

Species and tissue differences in regorafenib glucuronidation.

Published in:

Xenobiotica, 2022, v. 52, n. 2, p. 129, doi. 10.1080/00498254.2022.2055507

By:

Kojima, Ayaka;
Nadai, Masayuki;
Katoh, Miki

Publication type:

Article

Species differences in oxidative metabolism of regorafenib.

Published in:

Xenobiotica, 2021, v. 51, n. 12, p. 1400, doi. 10.1080/00498254.2022.2028935

By:

Kojima, Ayaka;
Sogabe, Ayuka;
Nadai, Masayuki;
Katoh, Miki

Publication type:

Article

Molecular Recognition between Anticancer Drug, Regorafenib and Human Serum Albumin: Interaction Revisited.

Published in:

Croatica Chemica Acta, 2022, v. 95, n. 2, p. 57, doi. 10.5562/cca3922

By:

Kandandapani, Salanee;
Kabir, Md. Zahirul;
Tayyab, Hafsa;
Mohamad, Saharuddin B.;
Tayyab, Saad

Publication type:

Article