Works matching DE "PYRUVATE dehydrogenase kinase"
Results: 375
Investigating the link between microplastic exposure (benzyl butyl phthalate) and neurodegenerative diseases using high-performance computational toxicology.
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- Toxicology Research, 2025, v. 14, n. 1, p. 1, doi. 10.1093/toxres/tfae211
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- Article
PDK2-enhanced glycolysis aggravates fibrosis via IL11 signaling pathway in Graves' orbitopathy.
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- Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1537365
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- Publication type:
- Article
Enhanced Antitumor Activity of Korean Black Soybean Cultivar 'Soman' by Targeting STAT-Mediated Aerobic Glycolysis.
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- Antioxidants, 2025, v. 14, n. 2, p. 228, doi. 10.3390/antiox14020228
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- Article
Reducing PDK4 level constitutes a pivotal mechanism for glucocorticoids to impede osteoblastic differentiation through the enhancement of ferroptosis in mesenchymal stem cells.
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- Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04186-9
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- Publication type:
- Article
Design, Synthesis, Molecular Docking and Biological Activity of New Piperidine and Piperazine Derivatives of Dichloroacetate as Potential Anticancer Agents.
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- Pharmaceutical Chemistry Journal, 2020, v. 54, n. 2, p. 148, doi. 10.1007/s11094-020-02172-4
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- Publication type:
- Article
Therapeutic potential of microglial SMEK1 in regulating H3K9 lactylation in cerebral ischemia-reperfusion.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07425-6
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- Publication type:
- Article
A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death.
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- Human Genetics, 2019, v. 138, n. 5, p. 515, doi. 10.1007/s00439-019-01973-2
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- Publication type:
- Article
Pdk3's role in RANKL-induced osteoclast differentiation: insights from a bone marrow macrophage model.
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- PeerJ, 2024, p. 1, doi. 10.7717/peerj.18222
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- Publication type:
- Article
The role of solar radiation and tidal emersion on oxidative stress and glutathione synthesis in mussels exposed to air.
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- PeerJ, 2023, p. 1, doi. 10.7717/peerj.15345
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- Publication type:
- Article
Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 170, doi. 10.1080/14756366.2016.1201812
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- Publication type:
- Article
CrossTalk opposing view: Exercise training volume is more important than training intensity to promote increases in mitochondrial content.
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- Journal of Physiology, 2019, v. 597, n. 16, p. 4115, doi. 10.1113/JP277634
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- Publication type:
- Article
Treading slowly through hypoxic waters: dichloroacetate to the rescue!
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- Journal of Physiology, 2018, v. 596, n. 15, p. 2957, doi. 10.1113/JP275898
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- Publication type:
- Article
Dichloroacetate reduces cisplatin-induced apoptosis by inhibiting the JNK/14-3-3/Bax/caspase-9 pathway and suppressing caspase-8 activation via cFLIP in murine tubular cells.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-75229-z
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- Publication type:
- Article
Elevated Level of Cerebrospinal Fluid Pyruvate Dehydrogenase Kinase 4 Is a Predictive Biomarker of Clinical Outcome after Subarachnoid Hemorrhage.
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- Brain Sciences (2076-3425), 2022, v. 12, n. 11, p. 1507, doi. 10.3390/brainsci12111507
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- Publication type:
- Article
Bioenergy Crisis in Coronavirus Diseases?
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- 2020
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- Publication type:
- Editorial
Angiotensin II Alters Mitochondrial Membrane Potential and Lipid Metabolism in Rat Colonic Epithelial Cells.
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- Biomolecules (2218-273X), 2024, v. 14, n. 8, p. 974, doi. 10.3390/biom14080974
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- Publication type:
- Article
Interaction between Butyrate and Tumor Necrosis Factor α in Primary Rat Colonocytes.
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- Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 258, doi. 10.3390/biom13020258
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- Publication type:
- Article
Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats.
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- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00523
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- Publication type:
- Article
Reduction of mitochondria and up regulation of pyruvate dehydrogenase kinase 4 of skeletal muscle in patients with chronic kidney disease.
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- Nephrology, 2020, v. 25, n. 3, p. 230, doi. 10.1111/nep.13606
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- Publication type:
- Article
Study on the Regulatory Mechanism of the PDK1-Mediated TGF-β/Smad Signaling Pathway in Hypoxia-Induced Yak Lungs.
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- Animals (2076-2615), 2024, v. 14, n. 16, p. 2422, doi. 10.3390/ani14162422
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- Publication type:
- Article
Study of Transcriptomic Analysis of Yak (Bos grunniens) and Cattle (Bos taurus) Pulmonary Artery Smooth Muscle Cells under Oxygen Concentration Gradients and Differences in Their Lung Histology and Expression of Pyruvate Dehydrogenase Kinase 1-Related Factors
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- Animals (2076-2615), 2023, v. 13, n. 22, p. 3450, doi. 10.3390/ani13223450
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- Publication type:
- Article
Nutritional Properties and Oxidative Indices of Broiler Breast Meat Affected by Wooden Breast Abnormality.
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- Animals (2076-2615), 2020, v. 10, n. 12, p. 2272, doi. 10.3390/ani10122272
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- Publication type:
- Article
Detecting de novo Hepatic Ketogenesis Using Hyperpolarized [2-<sup>13</sup>C] Pyruvate.
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- Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.832403
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- Publication type:
- Article
Trained immunity: A key player of "metabolic memory" in diabetes.
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- Journal of Diabetes Investigation, 2022, v. 13, n. 4, p. 608, doi. 10.1111/jdi.13734
- Publication type:
- Article
GPR30 Selective Agonist G1 Exhibits Antiobesity Effects and Promotes Insulin Resistance and Gluconeogenesis in Postmenopausal Mice Fed a High‐Fat Diet.
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- Journal of Lipids, 2024, v. 2024, p. 1, doi. 10.1155/2024/5513473
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- Publication type:
- Article
Endurance training and pyruvate dehydrogenase kinase 4 (PDK4) inhibition combination is superior to each one alone in attenuating hyperketonemia/ketoacidosis in diabetic rats.
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- Iranian Journal of Basic Medical Sciences, 2025, v. 28, n. 1, p. 80, doi. 10.22038/ijbms.2024.79864.17305
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- Publication type:
- Article
A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats.
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- PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0222558
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- Publication type:
- Article
Carnosine inhibits glioblastoma growth independent from PI3K/Akt/mTOR signaling.
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- PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218972
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- Publication type:
- Article
Inhibition of Pyruvate Dehydrogenase Kinase 4 Protects Cardiomyocytes from lipopolysaccharide-Induced Mitochondrial Damage by Reducing Lactate Accumulation.
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- Inflammation, 2024, v. 47, n. 4, p. 1356, doi. 10.1007/s10753-024-01981-z
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- Publication type:
- Article
Pyruvate Dehydrogenase Kinase 2 Accelerates Endotoxin Shock by Promoting Mitogen-Activated Protein Kinase Activation.
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- Inflammation, 2023, v. 46, n. 1, p. 418, doi. 10.1007/s10753-022-01744-8
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- Publication type:
- Article
Baseline Gene Expression Analysis in the Peripheral Blood of Patients With Rheumatoid Arthritis as an Important Supplement to Standard Composite Measure.
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- 2023
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- Publication type:
- Letter to the Editor
Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity.
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- Acta Physiologica, 2014, v. 210, n. 2, p. 392, doi. 10.1111/apha.12183
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- Publication type:
- Article
The effect of continuous and interval exercise on PGC-1α and PDK4 mRNA in type I and type II fibres of human skeletal muscle.
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- Acta Physiologica, 2012, v. 204, n. 4, p. 525, doi. 10.1111/j.1748-1716.2011.02354.x
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- Publication type:
- Article
Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis.
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- Journal of Neuroscience, 2015, v. 35, n. 42, p. 14353, doi. 10.1523/JNEUROSCI.1910-15.2015
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- Publication type:
- Article
Hepatitis B Virus and Hepatitis C Virus Affect Mitochondrial Function Through Different Metabolic Pathways, Explaining Virus-Specific Clinical Features of Chronic Hepatitis.
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- Journal of Infectious Diseases, 2024, v. 230, n. 5, p. e1012, doi. 10.1093/infdis/jiae210
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- Publication type:
- Article
Inhibition of Pyruvate Dehydrogenase Kinase 4 Attenuates Myocardial and Mitochondrial Injury in Sepsis-Induced Cardiomyopathy.
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- Journal of Infectious Diseases, 2024, v. 229, n. 4, p. 1178, doi. 10.1093/infdis/jiad365
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- Publication type:
- Article
Pyruvate Dehydrogenase Kinase 1 inhibition mediated oxidative phosphorylation enhancement in cartilage promotes osteoarthritis progression.
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- BMC Musculoskeletal Disorders, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12891-023-06585-6
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- Publication type:
- Article
Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms.
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- PLoS Genetics, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.pgen.1008410
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- Publication type:
- Article
The effect of HIF-1α on glucose metabolism, growth and apoptosis of pancreatic cancerous cells.
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- Asia Pacific Journal of Clinical Nutrition, 2014, v. 23, n. 1, p. 174, doi. 10.6133/apjcn.2014.23.1.14
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- Publication type:
- Article
Interaction of pretilachlor with PS‐II activity of the cyanobacterium Desmonostoc muscorum PUPCCC 405.10.
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- Journal of Basic Microbiology, 2020, v. 60, n. 6, p. 532, doi. 10.1002/jobm.201900706
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- Publication type:
- Article
Exploring diet-induced promoter hypomethylation and PDK4 overexpression: implications for type 2 diabetes mellitus.
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- Molecular Biology Reports, 2023, v. 50, n. 11, p. 8949, doi. 10.1007/s11033-023-08794-7
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- Publication type:
- Article
Ortho‐phenylphenol exposure impairs porcine sperm motility through AMPK/AKT signaling pathway.
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- Environmental & Molecular Mutagenesis, 2019, v. 60, n. 9, p. 830, doi. 10.1002/em.22324
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- Publication type:
- Article
Effects of intermittent hypoxia training on leukocyte pyruvate dehydrogenase kinase 1 (PDK-1) mRNA expression and blood insulin level in prediabetes patients.
- Published in:
- 2019
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- Publication type:
- journal article
Glut1 expression is increased by p53 reduction to switch metabolism to glycolysis during osteoblast differentiation.
- Published in:
- Biochemical Journal, 2020, v. 477, n. 10, p. 1795, doi. 10.1042/BCJ20190888
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- Publication type:
- Article
Arsenite retards DNA break rejoining by inhibiting DNA ligation.
- Published in:
- Mutagenesis, 1997, v. 12, n. 5, p. 353, doi. 10.1093/mutage/12.5.353
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- Publication type:
- Article
Evidence for Hypoxia-Induced Shift in ATP Production from Glycolysis to Mitochondrial Respiration in Pulmonary Artery Smooth Muscle Cells in Pulmonary Arterial Hypertension.
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- Journal of Clinical Medicine, 2023, v. 12, n. 15, p. 5028, doi. 10.3390/jcm12155028
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- Publication type:
- Article
High Expression of PDK4 Could Play a Potentially Protective Role by Attenuating Oxidative Stress after Subarachnoid Hemorrhage.
- Published in:
- Journal of Clinical Medicine, 2022, v. 11, n. 14, p. 3974, doi. 10.3390/jcm11143974
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- Publication type:
- Article
Targeting Endothelial Cell Metabolism by Inhibition of Pyruvate Dehydrogenase Kinase and Glutaminase-1.
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- Journal of Clinical Medicine, 2020, v. 9, n. 10, p. 3308, doi. 10.3390/jcm9103308
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- Publication type:
- Article
Sodium Phenylbutyrate Attenuates Cisplatin-Induced Acute Kidney Injury Through Inhibition of Pyruvate Dehydrogenase Kinase 4.
- Published in:
- Biomedicines, 2024, v. 12, n. 12, p. 2815, doi. 10.3390/biomedicines12122815
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- Publication type:
- Article
Genetic Ablation of Pyruvate Dehydrogenase Kinase Isoform 4 Gene Enhances Recovery from Hyperoxic Lung Injury: Insights into Antioxidant and Inflammatory Mechanisms.
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- Biomedicines, 2024, v. 12, n. 4, p. 746, doi. 10.3390/biomedicines12040746
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- Publication type:
- Article