Works matching DE "PYRUVATE dehydrogenase complex"

Results: 265

Astragaloside IV increases PDHA1 in mesenchymal stem cell exosomes to treat myocardial infarction.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-08628-5

By:

Zhongxin, Sha;
Zhijie, Chen;
Feng, Du;
Qin, Guo Mei;
Ya, Zhong;
Jinxin, Hu;
Zhang, Wei;
Zhenqiu, Yu

Publication type:

Article

Anesthesia management for ENT surgery in a child with X‐linked pyruvate kinase deficiency.

Published in:

Pediatric Anesthesia, 2021, v. 31, n. 4, p. 499, doi. 10.1111/pan.14105

By:

Hau, Vickie;
Bonilla‐Velez, Juliana;
Low, Daniel;
Veyckemans, Francis

Publication type:

Article

Impact of combination antiretroviral therapy in the NOD.c3c4 mouse model of autoimmune biliary disease.

Published in:

Liver International, 2015, v. 35, n. 4, p. 1442, doi. 10.1111/liv.12699

By:

Sharon, David;
Chen, Min;
Zhang, Guangzhi;
Girgis, Safwat;
Sis, Banu;
Graham, Don;
McDougall, Chelsea;
Wasilenko, Shawn T.;
Montano‐Loza, Aldo;
Mason, Andrew L.

Publication type:

Article

Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-021-00427-8

By:

Li, Dongze;
Xu, Na;
Hou, Yanyan;
Ren, Wenjing;
Zhang, Na;
Wang, Xi;
Sun, Yeying;
Lu, Wenxue;
Qu, Guiwu;
Yu, Yan;
Lv, Changjun;
Han, Fang

Publication type:

Article

The Opening of 1,2‐Dithiolanes and 1,2‐Diselenolanes: Regioselectivity, Rearrangements, and Consequences for Poly(disulfide)s, Cellular Uptake and Pyruvate Dehydrogenase Complexes.

Published in:

Helvetica Chimica Acta, 2019, v. 102, n. 2, p. N.PAG, doi. 10.1002/hlca.201800209

By:

Laurent, Quentin;
Sakai, Naomi;
Matile, Stefan

Publication type:

Article

Metabolic flux analysis of Escherichia coli MG1655 under octanoic acid (C8) stress.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 10, p. 4397, doi. 10.1007/s00253-015-6387-6

By:

Fu, Yanfen;
Yoon, Jong;
Jarboe, Laura;
Shanks, Jacqueline

Publication type:

Article

Effects of pyruvate dehydrogenase subunits overexpression on the α-ketoglutarate production in Yarrowia lipolytica WSH-Z06.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 16, p. 7003, doi. 10.1007/s00253-014-5745-0

By:

Guo, Hongwei;
Madzak, Catherine;
Du, Guocheng;
Zhou, Jingwen;
Chen, Jian

Publication type:

Article

Modulation of copper homeostasis and cuproptosis by PDHA1 in acute myeloid leukemia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02814-7

By:

Chen, Tianping;
Wei, Nan;
Lv, Wenxiu;
Qu, Lijun;
Qu, Qian;
Wu, Chaohong;
Ling, Yuan;
Liu, Haipeng;
Liu, Hongjun

Publication type:

Article

Isoacteoside alleviates hepatocellular carcinoma progression by inhibiting PDHB-mediated reprogramming of glucose metabolism.

Published in:

Communications Biology, 2025, p. 1, doi. 10.1038/s42003-025-07622-x

By:

Zhao, Lijun;
Qi, Haonan;
Liu, Weiting;
Lv, Huiying;
Li, Peixian;
Liu, Wenyue;
Sun, Ruili;
Wang, Qiongzi;
Wang, Xiangpeng

Publication type:

Article

A novel aceE mutation leading to a better growth profile and a higher l-serine production in a high-yield l-serine-producing Corynebacterium glutamicum strain.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2016, v. 43, n. 9, p. 1293, doi. 10.1007/s10295-016-1801-3

By:

Guo, Wen;
Chen, Ziwei;
Zhang, Xiaomei;
Xu, Guoqiang;
Zhang, Xiaojuan;
Shi, Jinsong;
Xu, Zhenghong

Publication type:

Article

Engineering a homobutanol fermentation pathway in Escherichia coli EG03.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2012, v. 39, n. 8, p. 1101, doi. 10.1007/s10295-012-1151-8

By:

Garza, Erin;
Zhao, Jinfang;
Wang, Yongze;
Wang, Jinhua;
Iverson, Andrew;
Manow, Ryan;
Finan, Chris;
Zhou, Shengde

Publication type:

Article

Partial deletion of rng (RNase G)-enhanced homoethanol fermentation of xylose by the non-transgenic Escherichia coli RM10.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2012, v. 39, n. 7, p. 977, doi. 10.1007/s10295-012-1100-6

By:

Manow, Ryan;
Wang, Jinhua;
Wang, Yongze;
Zhao, Jinfang;
Garza, Erin;
Iverson, Andrew;
Finan, Chris;
Grayburn, Scott;
Zhou, Shengde

Publication type:

Article

Blood-Based Lateral-Flow Immunoassays Dipstick Test for Damaged Mitochondrial Electron Transport Chain in Pyruvate Treated Rats with Combined Blast Exposure and Hemorrhagic Shock.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 3, p. 754, doi. 10.3390/jcm14030754

By:

Okonkwo, Evans;
Saha, Biswajit;
Sahu, Geetaram;
Bera, Alakesh;
Sharma, Pushpa

Publication type:

Article

Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1151502

By:

Seik-Soon Khor;
Kazuko Ueno;
Nao Nishida;
Minae Kawashima;
Yosuke Kawai;
Yoshihiro Aiba;
Yuki Hitomi;
Masao Nagasaki;
Minoru Nakamura;
Katsushi Tokunaga

Publication type:

Article

Emerging roles of pyruvate dehydrogenase phosphatase 1: a key player in metabolic health.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1596636

By:

Kumar, Vikalp;
Greenberg, Miriam L.

Publication type:

Article

Linking Human Betaretrovirus with Autoimmunity and Liver Disease in Patients with Primary Biliary Cholangitis.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 9, p. 1941, doi. 10.3390/v14091941

By:

Syed, Hussain;
Penner, Tara;
Mason, Andrew L.

Publication type:

Article

Protein-Sparing Effect of α-Lipoic Acid in Diets with Different Protein/Carbohydrate Ratios for the Oriental River Prawn, Macrobrachium nipponense.

Published in:

Aquaculture Research, 2023, p. 1, doi. 10.1155/2023/5614359

By:

Li, Shanshan;
Wang, Junbao;
Xiong, Yunfeng;
Zheng, Jinxian;
Zhou, Dongsheng;
Zhao, Jianhua;
Ding, Zhili

Publication type:

Article

A modified Atkin's diet for an infant with pyruvate dehydrogenase complex deficiency confirmed by PDHA1 gene mutation.

Published in:

2014

By:

Kim, Jeong A.;
Rita Yu;
Wonha Jo;
Youn Hee Ko;
Jin-Sung Lee;
Heung Dong Kim;
Hoon-Chul Kang

Publication type:

Case Study

Engineering Corynebacterium glutamicum Mutants for 3-Methyl-1-butanol Production.

Published in:

Biochemical Genetics, 2019, v. 57, n. 3, p. 443, doi. 10.1007/s10528-019-09906-4

By:

Zhang, Yu;
Zhang, Xiaohuan;
Xiao, Shiyuan;
Qi, Wei;
Xu, Jingliang;
Yuan, Zhenhong;
Wang, Zhongming

Publication type:

Article

Aminoacidopathies: Prevalence, Etiology, Screening, and Treatment Options.

Published in:

Biochemical Genetics, 2018, v. 56, n. 1/2, p. 7, doi. 10.1007/s10528-017-9825-6

By:

Wasim, Muhammad;
Awan, Fazli Rabbi;
Khan, Haq Nawaz;
Tawab, Abdul;
Iqbal, Mazhar;
Ayesha, Hina

Publication type:

Article

Pyruvate dehydrogenase complex deficiency: updating the clinical, metabolic and mutational landscapes in a cohort of Portuguese patients.

Published in:

2020

By:

Pavlu-Pereira, Hana;
Silva, Maria João;
Florindo, Cristina;
Sequeira, Sílvia;
Ferreira, Ana Cristina;
Duarte, Sofia;
Rodrigues, Ana Luísa;
Janeiro, Patrícia;
Oliveira, Anabela;
Gomes, Daniel;
Bandeira, Anabela;
Martins, Esmeralda;
Gomes, Roseli;
Soares, Sérgia;
Tavares de Almeida, Isabel;
Vicente, João B.;
Rivera, Isabel

Publication type:

journal article

Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation.

Published in:

Clinical Science, 2014, v. 127, n. 5, p. 315, doi. 10.1042/CS20140031

By:

STEPHENS, Francis B.;
MENDIS, Buddhike;
SHANNON, Chris E.;
COOPER, Scott;
ORTORI, Catharine A.;
BARRETT, David A.;
MANSELL, Peter;
TSINTZAS, Kostas

Publication type:

Article

Impaired hippocampal glucose metabolism during and after flurothyl-induced seizures in mice: Reduced phosphorylation coincides with reduced activity of pyruvate dehydrogenase.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 7, p. 1172, doi. 10.1111/epi.13796

By:

McDonald, Tanya S.;
Borges, Karin

Publication type:

Article

Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics.

Published in:

Epilepsia (Series 4), 2015, v. 56, n. 8, p. 1185, doi. 10.1111/epi.13057

By:

Wilmshurst, Jo M.;
Gaillard, William D.;
Vinayan, Kollencheri Puthenveettil;
Tsuchida, Tammy N.;
Plouin, Perrine;
Van Bogaert, Patrick;
Carrizosa, Jaime;
Elia, Maurizio;
Craiu, Dana;
Jovic, Nebojsa J.;
Nordli, Doug;
Hirtz, Deborah;
Wong, Virginia;
Glauser, Tracy;
Mizrahi, Eli M.;
Cross, J. Helen

Publication type:

Article

Protein complexes in cells by AI‐assisted structural proteomics.

Published in:

Molecular Systems Biology, 2023, v. 19, n. 4, p. 1, doi. 10.15252/msb.202311544

By:

O'Reilly, Francis J;
Graziadei, Andrea;
Forbrig, Christian;
Bremenkamp, Rica;
Charles, Kristine;
Lenz, Swantje;
Elfmann, Christoph;
Fischer, Lutz;
Stülke, Jörg;
Rappsilber, Juri

Publication type:

Article

Glycerol, a possible new player in the biology of trypanosomes.

Published in:

PLoS Pathogens, 2021, v. 17, n. 12, p. 1, doi. 10.1371/journal.ppat.1010035

By:

Bringaud, Frédéric;
Plazolles, Nicolas;
Pineda, Erika;
Asencio, Corinne;
Villafraz, Oriana;
Millerioux, Yoann;
Rivière, Loïc;
Tetaud, Emmanuel

Publication type:

Article

Hyperpolarized <sup>13</sup>C‐MRS can Quantify Lactate Production and Oxidative PDH Flux in Murine Skeletal Muscle During Exercise.

Published in:

NMR in Biomedicine, 2025, v. 38, n. 5, p. 1, doi. 10.1002/nbm.70020

By:

Curtis, M. Kate;
McGing, Jordan J.;
Stubbs, Brianna J.;
Ball, Vicky;
Cochlin, Lowri E.;
O'Neill, David P.;
Laustsen, Christoffer;
Cole, Mark A.;
Robbins, Peter A.;
Tyler, Damian J.;
Miller, Jack J.

Publication type:

Article

Metabolic preconditioning of mammalian cells: mimetic agents for hypoxia lack fidelity in promoting phosphorylation of pyruvate dehydrogenase.

Published in:

Cell & Tissue Research, 2013, v. 351, n. 1, p. 99, doi. 10.1007/s00441-012-1517-2

By:

Borcar, Apurva;
Menze, Michael;
Toner, Mehmet;
Hand, Steven

Publication type:

Article

Diabetes - clinical.

Published in:: Nephrology Dialysis Transplantation, 2013, v. 28, n. suppl_1, p. i16, doi. 10.1093/ndt/gft148
Publication type:: Article

Pyruvic Acid Production from Sucrose by Escherichia coli Pyruvate Dehydrogenase Variants.

Published in:

Fermentation (Basel), 2023, v. 9, n. 5, p. 478, doi. 10.3390/fermentation9050478

By:

Moxley, W. Chris;
Eiteman, Mark A.

Publication type:

Article

Metabolic stroke-like events in a girl with pyruvate dehydrogenase complex deficiency caused by a novel de novo mutation in PDHA1.

Published in:

Neurological Sciences, 2024, v. 45, n. 6, p. 2913, doi. 10.1007/s10072-024-07355-5

By:

Fecarotta, Simona;
D'Amico, Alessandra;
Di Gennaro, Simona;
Alagia, Marianna;
Rossi, Alessandro;
Zuppaldi, Claudia;
Parenti, Giancarlo;
Terrone, Gaetano

Publication type:

Article

PDH Inhibition in Drosophila Ameliorates Sensory Dysfunction Induced by Vincristine Treatment in the Chemotherapy-Induced Peripheral Neuropathy Models.

Published in:

Biomedicines, 2025, v. 13, n. 4, p. 783, doi. 10.3390/biomedicines13040783

By:

Song, Harim;
Kim, Sohee;
Han, Ji Eun;
Kang, Kyong-hwa;
Koh, Hyongjong

Publication type:

Article

A Missense Variant in PDK1 Associated with Severe Neurodevelopmental Delay and Epilepsy.

Published in:

Biomedicines, 2022, v. 10, n. 12, p. 3171, doi. 10.3390/biomedicines10123171

By:

Vaz, Raquel;
Wincent, Josephine;
Elfissi, Najla;
Rosengren Forsblad, Kristina;
Pettersson, Maria;
Naess, Karin;
Wedell, Anna;
Wredenberg, Anna;
Lindstrand, Anna;
Ygberg, Sofia

Publication type:

Article

Pyruvate Dehydrogenase A1 Phosphorylated by Insulin Associates with Pyruvate Kinase M2 and Induces LINC00273 through Histone Acetylation.

Published in:

Biomedicines, 2022, v. 10, n. 6, p. 1256, doi. 10.3390/biomedicines10061256

By:

Hossain, Abu Jubayer;
Islam, Rokibul;
Kim, Jae-Gyu;
Dogsom, Oyungerel;
Cap, Kim Cuong;
Park, Jae-Bong

Publication type:

Article

Clinical, Molecular, and Histopathological Aspect of Primary Biliary Cholangitis.

Published in:

Indonesian Journal of Gastroenterology, Hepatology & Digestive Endoscopy, 2019, v. 20, n. 3, p. 177

By:

Dameria, Flora;
Stephanie, Marini;
Kodariah, Ria;
Handjari, Diah Rini;
Krisnuhoni, Ening;
Rahadiani, Nur

Publication type:

Article

Exploring PDK3 inhibition in lung cancer through drug repurposing for potential therapeutic interventions.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-78022-0

By:

Khan, Zeba Firdos;
Rathi, Aanchal;
Khan, Afreen;
Anjum, Farah;
Chaudhury, Arunabh;
Taiyab, Aaliya;
Shamsi, Anas;
Hassan, Md. Imtaiyaz

Publication type:

Article

Pyruvate Regulates the Expression of DLAT to Promote Follicular Growth.

Published in:

Cells (2073-4409), 2025, v. 14, n. 6, p. 444, doi. 10.3390/cells14060444

By:

Zhang, Liuhong;
Guo, Yixuan;
Huang, Enyuan;
Lu, Jianing;
Wang, Tiantian;
Shi, Yonghua;
Lv, Meng;
Chen, Yongcai;
Li, Shuo;
Yuan, Xiaolong;
Li, Jiaqi

Publication type:

Article

Oxidative Glucose Metabolism Promotes Senescence in Vascular Endothelial Cells.

Published in:

Cells (2073-4409), 2022, v. 11, n. 14, p. N.PAG, doi. 10.3390/cells11142213

By:

Stabenow, Leonie K.;
Zibrova, Darya;
Ender, Claudia;
Helbing, Dario L.;
Spengler, Katrin;
Marx, Christian;
Wang, Zhao-Qi;
Heller, Regine

Publication type:

Article

The Metabolic Fates of Pyruvate in Normal and Neoplastic Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 4, p. 762, doi. 10.3390/cells10040762

By:

Prochownik, Edward V.;
Wang, Huabo;
Cantelmo, Anna Rita

Publication type:

Article

Wheat mitochondrial respiration shifts from the tricarboxylic acid cycle to the GABA shunt under salt stress.

Published in:

New Phytologist, 2020, v. 225, n. 3, p. 1166, doi. 10.1111/nph.15713

By:

Che‐Othman, M. Hafiz;
Jacoby, Richard P.;
Millar, A. Harvey;
Taylor, Nicolas L.

Publication type:

Article

Overexpression of Pyruvate Dehydrogenase Kinase-3 Predicts Poor Prognosis in Urothelial Carcinoma.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.749142

By:

Kuo, Yu-Hsuan;
Chan, Ti-Chun;
Lai, Hong-Yue;
Chen, Tzu-Ju;
Wu, Li-Ching;
Hsing, Chung-Hsi;
Li, Chien-Feng

Publication type:

Article

Downregulation of miR-181b-5p Inhibits the Viability, Migration, and Glycolysis of Gallbladder Cancer by Upregulating PDHX Under Hypoxia.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.683725

By:

Qin, Yiyu;
Zheng, Yongliang;
Huang, Cheng;
Li, Yuanyuan;
Gu, Min;
Wu, Qin

Publication type:

Article

The Implications of PDK1–4 on Tumor Energy Metabolism, Aggressiveness and Therapy Resistance.

Published in:

Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.583217

By:

Atas, Emine;
Oberhuber, Monika;
Kenner, Lukas

Publication type:

Article

A 'Split-Gene' Transketolase From the Hyper-Thermophilic Bacterium Carboxydothermus hydrogenoformans : Structure and Biochemical Characterization.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.592353

By:

James, Paul;
Isupov, Michail N.;
De Rose, Simone Antonio;
Sayer, Christopher;
Cole, Isobel S.;
Littlechild, Jennifer A.

Publication type:

Article

Initial Transcriptomic Response and Adaption of Listeria monocytogenes to Desiccation on Food Grade Stainless Steel.

Published in:

Frontiers in Microbiology, 2020, v. 10, p. 1, doi. 10.3389/fmicb.2019.03132

By:

Kragh, Martin Laage;
Truelstrup Hansen, Lisbeth

Publication type:

Article

The Link between Mitochondrial Dysfunction and Sarcopenia: An Update Focusing on the Role of Pyruvate Dehydrogenase Kinase 4.

Published in:

Diabetes & Metabolism Journal, 2023, v. 47, n. 2, p. 153, doi. 10.4093/dmj.2022.0305

By:

Min-Ji Kim;
Sinam, Ibotombi Singh;
Siddique, Zerwa;
Jae-Han Jeon;
In-Kyu Lee

Publication type:

Article

Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism.

Published in:

Diabetes & Metabolism Journal, 2018, v. 42, n. 4, p. 270, doi. 10.4093/dmj.2018.0101

By:

Sungmi Park;
Jae-Han Jeon;
Byong-Keol Min;
Chae-Myeong Ha;
Themis Thoudam;
Bo-Yoon Park;
In-Kyu Lee

Publication type:

Article

Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27287-4

By:

Tüting, Christian;
Kyrilis, Fotis L.;
Müller, Johannes;
Sorokina, Marija;
Skalidis, Ioannis;
Hamdi, Farzad;
Sadian, Yashar;
Kastritis, Panagiotis L.

Publication type:

Article

Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25570-y

By:

Škerlová, Jana;
Berndtsson, Jens;
Nolte, Hendrik;
Ott, Martin;
Stenmark, Pål

Publication type:

Article

Kruppel‐like factor 15 regulates fuel switching between glucose and fatty acids in brown adipocytes.

Published in:

Journal of Diabetes Investigation, 2021, v. 12, n. 7, p. 1144, doi. 10.1111/jdi.13511

By:

Nabatame, Yuko;
Hosooka, Tetsuya;
Aoki, Chikako;
Hosokawa, Yusei;
Imamori, Makoto;
Tamori, Yoshikazu;
Okamatsu‐Ogura, Yuko;
Yoneshiro, Takeshi;
Kajimura, Shingo;
Saito, Masayuki;
Ogawa, Wataru

Publication type:

Article