Works matching DE "PYROPTOSIS"
Results: 1905
Quercetin attenuates the symptoms of osteoarthritis in vitro and in vivo by suppressing ferroptosis via activation of AMPK/Nrf2/Gpx4 signaling.
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- Molecular Medicine Reports, 2025, v. 31, n. 3, p. N.PAG, doi. 10.3892/mmr.2024.13425
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Remimazolam Combined with Andrographolide Improve Postoperative Cognitive Dysfunction in Rats after Cardiopulmonary Bypass through the AMPK/SIRT1 Signaling Pathway.
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- Journal of Integrative Neuroscience, 2025, v. 24, n. 1, p. 1, doi. 10.31083/JIN25665
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Microglial C/EBPβ-Fcgr1 regulatory axis blocking inhibits microglial pyroptosis and improves neurological recovery.
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- Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03362-1
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Protective effect and mechanism of Sufentanil on acute lung injury in septic mice.
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- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1514602
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Inflammatory activity and apoptosis are associated with tissue degeneration in the submandibular gland of rats submitted to paradoxical sleep deprivation.
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- Odontology, 2022, v. 110, n. 2, p. 278, doi. 10.1007/s10266-021-00657-6
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The Role of miR-150-5p/SOCS1 Pathway in Arsenic-Induced Pyroptosis of LX-2 Cells.
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- Biological Trace Element Research, 2025, v. 203, n. 2, p. 822, doi. 10.1007/s12011-024-04211-7
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Nickel Induces Pyroptosis via the Nrf2/NLRP3 Pathway in Kidney of Mice.
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- Biological Trace Element Research, 2024, v. 202, n. 7, p. 3248, doi. 10.1007/s12011-023-03922-7
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Selenium Deficiency via the ROS/NLRP3/IL-1β Signaling Pathway Leads to Pyroptosis Injury in Pig Spleen.
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- Biological Trace Element Research, 2023, v. 201, n. 11, p. 5192, doi. 10.1007/s12011-023-03595-2
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MgCl<sub>2</sub> Attenuates ox-LDL-Induced Vascular Smooth Muscle–Derived Foam Cells Pyroptosis by Downregulating the TLR4/NF-κB Signaling Pathway.
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- Biological Trace Element Research, 2023, v. 201, n. 11, p. 5242, doi. 10.1007/s12011-023-03585-4
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ZnT8 Exerts Anti-apoptosis of Kidney Tubular Epithelial Cell in Diabetic Kidney Disease Through TNFAIP3-NF-κB Signal Pathways.
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- Biological Trace Element Research, 2023, v. 201, n. 5, p. 2442, doi. 10.1007/s12011-022-03361-w
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- Article
Curcumin Alleviates Arsenic Trioxide–Induced Inflammation and Pyroptosis via the NF-κB/NLRP3 Signaling Pathway in the Hypothalamus of Ducks.
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- Biological Trace Element Research, 2023, v. 201, n. 5, p. 2503, doi. 10.1007/s12011-022-03321-4
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- Article
Molybdenum and Cadmium Co-induce Pyroptosis via Inhibiting Nrf2-Mediated Antioxidant Defense Response in the Brain of Ducks.
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- Biological Trace Element Research, 2023, v. 201, n. 2, p. 874, doi. 10.1007/s12011-022-03170-1
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Yeast Selenium Exerts an Antioxidant Effect by Regulating the Level of Selenoprotein to Antagonize Cd-Induced Pyroptosis of Chicken Liver.
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- Biological Trace Element Research, 2022, v. 200, n. 9, p. 4079, doi. 10.1007/s12011-021-02984-9
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Inflammasome and Inflammatory Programmed Cell Death in Chromoblastomycosis.
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- Mycopathologia, 2023, v. 188, n. 1/2, p. 63, doi. 10.1007/s11046-022-00679-w
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The relationship between liver pathological inflammation degree and pyroptosis in chronic hepatitis B patients.
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- Journal of Medical Virology, 2021, v. 93, n. 11, p. 6229, doi. 10.1002/jmv.27114
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- Article
Homocysteine promotes atherosclerosis through macrophage pyroptosis via endoplasmic reticulum stress and calcium disorder.
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- Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00656-z
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- Article
MALAT1 knockdown alleviates the pyroptosis of microglias in diabetic cerebral ischemia via regulating STAT1 mediated NLRP3 transcription.
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- Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00637-2
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BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity.
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- Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00623-8
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Relevance of the pyroptosis-related inflammasome drug targets in the Chuanxiong to improve diabetic nephropathy.
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- Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00567-5
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LncRNA FENDRR with m6A RNA methylation regulates hypoxia-induced pulmonary artery endothelial cell pyroptosis by mediating DRP1 DNA methylation.
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- Molecular Medicine, 2022, v. 28, p. 1, doi. 10.1186/s10020-022-00551-z
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- Article
LINC00240/miR-155 axis regulates function of trophoblasts and M2 macrophage polarization via modulating oxidative stress-induced pyroptosis in preeclampsia.
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- Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00531-3
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- Article
Long noncoding RNA MAPKAPK5-AS1 promoted lipopolysaccharide-induced inflammatory damage in the myocardium by sponging microRNA-124-3p/E2F3.
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- Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00385-1
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Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3.
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- Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00355-7
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- Article
Novel GSDMD inhibitor GI-Y1 protects heart against pyroptosis and ischemia/reperfusion injury by blocking pyroptotic pore formation.
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- Basic Research in Cardiology, 2023, v. 118, n. 1, p. 1, doi. 10.1007/s00395-023-01010-4
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- Article
The necroptosis cell death pathway drives neurodegeneration in Alzheimer's disease.
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- Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02747-5
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Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons.
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- Acta Neuropathologica, 2023, v. 145, n. 2, p. 175, doi. 10.1007/s00401-022-02528-y
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Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex.
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- Acta Neuropathologica, 2022, v. 144, n. 3, p. 393, doi. 10.1007/s00401-022-02466-9
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Mesenchymal stem cell-derived exosomal microRNA-367-3p mitigates lower limb ischemia/reperfusion injury in mouse skeletal muscle via EZH2 targeting.
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- Journal of Pharmacy & Pharmacology, 2024, v. 76, n. 12, p. 1634, doi. 10.1093/jpp/rgae086
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Investigation of polysaccharide from Radix Aconiti Lateralis Preparata (Fuzi) cardio protective effect on doxorubicin-induced chronic cardiotoxicity.
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- Journal of Pharmacy & Pharmacology, 2024, v. 76, n. 4, p. 391, doi. 10.1093/jpp/rgae001
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- Article
Puerarin alleviates diabetic nephropathy by inhibiting Caspase-1-mediated pyroptosis.
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- Journal of Pharmacy & Pharmacology, 2024, v. 76, n. 3, p. 213, doi. 10.1093/jpp/rgad113
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- Article
Codonopsis pilosula polysaccharide suppresses the progression of non-small cell lung cancer by triggering NLRP3/GSDMD-dependent pyroptosis.
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- Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01361-x
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Investigation of nickel sulfate‐induced cytotoxicity and underlying toxicological mechanisms in human umbilical vein endothelial cells through oxidative stress, inflammation, apoptosis, and MAPK signaling pathways.
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- Environmental Toxicology, 2022, v. 37, n. 8, p. 2058, doi. 10.1002/tox.23550
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Endoplasmic reticulum stress regulates pyroptosis in BPDE‐induced BEAS‐2B cells.
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- Environmental Toxicology, 2022, v. 37, n. 7, p. 1768, doi. 10.1002/tox.23524
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- Article
Selenium protects against cadmium‐induced cardiac injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling.
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- Environmental Toxicology, 2022, v. 37, n. 5, p. 1185, doi. 10.1002/tox.23475
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- Article
C1q/tumor necrosis factor‐related protein 9 protects cultured chondrocytes from IL‐1β‐induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis.
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- Environmental Toxicology, 2022, v. 37, n. 4, p. 889, doi. 10.1002/tox.23452
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- Article
Lithium intoxication induced pyroptosis via ROS/NF‐κB/NLRP3 inflammasome regulatory networks in kidney of mice.
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- Environmental Toxicology, 2022, v. 37, n. 4, p. 825, doi. 10.1002/tox.23446
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- Article
β‐Amyrin ameliorates diabetic nephropathy in mice and regulates the miR‐181b‐5p/HMGB2 axis in high glucose‐stimulated HK‐2 cells.
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- Environmental Toxicology, 2022, v. 37, n. 3, p. 637, doi. 10.1002/tox.23431
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- Article
Microcrystalline silica particles induce inflammatory response via pyroptosis in primary human respiratory epithelial cells.
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- Environmental Toxicology, 2022, v. 37, n. 3, p. 385, doi. 10.1002/tox.23405
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- Article
The role of curcumin on apoptosis and NLRP3 inflammasome-dependent pyroptosis on colorectal cancer in vitro.
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- Turkish Journal of Medical Sciences, 2023, v. 53, n. 4, p. 883, doi. 10.55730/1300-0144.5652
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The role of anakinra in the modulation of intestinal cell apoptosis and inflammatory response during ischemia/reperfusion.
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- Turkish Journal of Medical Sciences, 2021, v. 51, n. 4, p. 2177, doi. 10.3906/sag-2008-258
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- Article
Pyroptosis and necroptosis inhibitor necrosulfonamide ameliorates lipopolysaccharide-induced inflammatory hyperalgesia in mice.
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- Pharmacia (0428-0296), 2023, v. 70, n. 4, p. 1345, doi. 10.3897/pharmacia.70.e108995
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Rational design, synthesis, and pharmacological characterisation of dicarbonyl curcuminoid analogues with improved stability against lung cancer via ROS and ER stress mediated cell apoptosis and pyroptosis.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2357, doi. 10.1080/14756366.2022.2116015
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Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1551, doi. 10.1080/14756366.2021.1948841
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miR-141-3p alleviates ulcerative colitis by targeting SUGT1 to inhibit colonic epithelial cell pyroptosis.
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- Autoimmunity, 2023, v. 56, n. 1, p. 1, doi. 10.1080/08916934.2023.2220988
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Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis.
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- Autoimmunity, 2023, v. 56, n. 1, p. 1, doi. 10.1080/08916934.2023.2250095
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- Article
Highly-expressed circ_0129657 inhibits proliferation as well as promotes apoptosis and inflammation in HBMECs after oxygen-glucose deprivation via miR-194-5p/GMFB axis.
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- Autoimmunity, 2023, v. 56, n. 1, p. 1, doi. 10.1080/08916934.2023.2201405
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RGS7 silence protects palmitic acid-induced pancreatic β-cell injury by inactivating the chemokine signaling pathway.
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- Autoimmunity, 2023, v. 56, n. 1, p. 1, doi. 10.1080/08916934.2023.2194584
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NR3C2 mediates oxidised low-density lipoprotein-induced human coronary endothelial cells dysfunction via modulation of NLRP3 inflammasome activation.
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- Autoimmunity, 2023, v. 56, n. 1, p. 1, doi. 10.1080/08916934.2023.2189135
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- Article
MiR-144-3p induced by SP1 promotes IL-1β-induced pyroptosis in chondrocytes via PTEN/PINK1/Parkin axis.
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- Autoimmunity, 2022, v. 55, n. 1, p. 21, doi. 10.1080/08916934.2021.1983802
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Circ_0114427 promotes LPS-induced septic acute kidney injury by modulating miR-495-3p/TRAF6 through the NF-κB pathway.
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- Autoimmunity, 2022, v. 55, n. 1, p. 52, doi. 10.1080/08916934.2021.1995861
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