Works matching DE "PYRIN (Protein)"

Results: 515

Placental inflammation is increased in gestational diabetes mellitus: The role of inflammasome NLRP-3 and chemokine scavenger decoy receptor D6.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0326087

By:

Onori, Marianna;
Beneduce, Giuliana;
Colella, Filomena;
Lucchetti, Donatella;
Policola, Caterina;
Arena, Vincenzo;
Sannino, Fabio;
Petrecca, Alessandro;
Pitocco, Dario;
Pontecorvi, Alfredo;
Sgambato, Alessandro;
Scambia, Giovanni;
Di Simone, Nicoletta;
Ghi, Tullio;
Tersigni, Chiara

Publication type:

Article

NOD2-NLRP3 Axis and Asthma.

Published in:

Journal of Asthma & Allergy, 2025, v. 18, p. 769, doi. 10.2147/JAA.S526788

By:

Cai, Xulong

Publication type:

Article

Kaempferol inhibits oxidative stress and reduces macrophage pyroptosis by activating the NRF2 signaling pathway.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325189

By:

Wang, Yu;
Chen, Chaofan;
Li, Yushan;
Li, Ran;
Wang, Jinghan;
Wu, Chao;
Chen, Haonan;
Shi, Yingchao;
Wang, Shengfang;
Gao, Chuanyu

Publication type:

Article

Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 1, p. N.PAG, doi. 10.3892/mmr.2025.13551

By:

Ma, Meng-Qing;
Yang, Chun;
Jin, Shi-Yu;
Yang, Yu;
Pan, Yan-Yan;
Lin, Xian-He

Publication type:

Article

Evolutionary and Functional Analysis of Caspase-8 and ASC Interactions to Drive Lytic Cell Death, PANoptosis Open Access.

Published in:

Molecular Biology & Evolution, 2025, v. 42, n. 5, p. 1, doi. 10.1093/molbev/msaf096

By:

Kumar, Sivakumar Prasanth;
Nadendla, Eswar Kumar;
Malireddi, R K Subbarao;
Haque, Syed Asfarul;
Mall, Raghvendra;
Neuwald, Andrew F;
Kanneganti, Thirumala-Devi

Publication type:

Article

Inflammasome-Mediated Neuroinflammation: A Key Driver in Alzheimer's Disease Pathogenesis.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 676, doi. 10.3390/biom15050676

By:

McGroarty, Julie;
Salinas, Shelbi;
Evans, Hayden;
Jimenez, Bryan;
Tran, Vincent;
Kadavakollu, Samuel;
Vashist, Arti;
Atluri, Venkata

Publication type:

Article

Tumor-derived vesicles in immune modulation: focus on signaling pathways.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1581964

By:

Yin, Fei;
He, Yangfang;
Qiao, Yue;
Yan, Yan

Publication type:

Article

Cholesterol crystals activate NLRP3 inflammasomes and promote gallstone formation by increasing mucin secretion.

Published in:

Biotechnic & Histochemistry, 2022, v. 97, n. 7, p. 546, doi. 10.1080/10520295.2022.2036813

By:

You-Ming Lei;
Ran Yan;
Yue-Dong Gao;
Hong-Ju Yang;
Hong-Yan Bi;
Yong-Qing Duan

Publication type:

Article

Newcastle Disease Virus Induces Pyroptosis in Canine Mammary Tumour CMT‐U27 Cells via the TNFα/NF‐κB/NLRP3 Signalling Pathway.

Published in:

Veterinary & Comparative Oncology, 2025, v. 23, n. 2, p. 224, doi. 10.1111/vco.13048

By:

Li, Mengqing;
Zhu, Yunjie;
Li, Meng

Publication type:

Article

Inhibition of phosphoinositide 3-kinase activity attenuates neutrophilic airway inflammation and inhibits pyrin domain-containing 3 inflammasome activation in an ovalbumin-lipopolysaccharide-induced asthma murine model.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09360-5

By:

Li, Qun;
Jiang, Guiyun;
Lv, Yunxiang

Publication type:

Article

NLRP3 inflammasome in cardiovascular diseases: Pathophysiological and pharmacological implications.

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 4, p. 1890, doi. 10.1002/med.21781

By:

Pellegrini, Carolina;
Martelli, Alma;
Antonioli, Luca;
Fornai, Matteo;
Blandizzi, Corrado;
Calderone, Vincenzo

Publication type:

Article

The Pivotal Role of Thioredoxin-Interacting Protein in Joint Degenerative Diseases.

Published in:

Trends in Sciences, 2025, v. 22, n. 3, p. 1, doi. 10.48048/tis.2025.9422

By:

Alshorman, Jamal;
Altahla, Ruba

Publication type:

Article

Indomethacin Affects the Inflammatory Response via Interaction with the RhoA-Actin Cytoskeleton in THP-1 Cells.

Published in:

Experimed, 2023, v. 13, n. 3, p. 213, doi. 10.26650/experimed.1364227

By:

Aldogan, Ebru Haciosmanoglu;
Yontem, Fulya Dal;
Bulut, Seyma;
Yapislar, Hande;
Guncer, Basak;
Bektas, Muhammet

Publication type:

Article

Evaluation of the frequency of MEFV gene variants in patients with a pre-diagnosis of Familial Mediterranean Fever (FMF) in southeast Türkiye.

Published in:

Pamukkale Medical Journal, 2023, v. 16, n. 3, p. 456, doi. 10.31362/patd.1255344

By:

Karaer, Derya;
Şahinoğlu, Bahtiyar;
Gürler, Abdullah İhsan;
Karaer, Kadri

Publication type:

Article

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03491-w

By:

Angosto-Bazarra, Diego;
Molina-López, Cristina;
Pelegrín, Pablo

Publication type:

Article

Neuroinflammation: Inflammatory brain drain.

Published in:

2013

By:

Bordon, Yvonne

Publication type:

journal article

Inflammasome: Turning on and off NLRP3.

Published in:

Nature Reviews Immunology, 2013, v. 13, n. 1, p. 1, doi. 10.1038/nri3366

By:

Leavy, Olive

Publication type:

Article

Identification of potential biomarkers for SLE through mRNA expression profiling.

Published in:

Journal of Immunoassay & Immunochemistry, 2024, v. 45, n. 1, p. 20, doi. 10.1080/15321819.2023.2266013

By:

Rizk, Sara Kamal;
Alhosary, Amal;
Zahran, Enas S.;
Awad, Samah;
Khalil, Marwa

Publication type:

Article

Study on the prognostic impact of interferon-gamma-inducible protein 16 level in multiple myeloma patients.

Published in:

Egyptian Journal of Haematology, 2024, v. 49, n. 4, p. 355, doi. 10.4103/ejh.ejh_21_24

By:

Nassar, Israa G.I.;
Saad, Mohamed A.;
Elkholy, Rasha A.;
Allam, Alzahraa A.

Publication type:

Article

The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 135, n. 2, p. 133, doi. 10.1111/bcpt.14037

By:

Lin, Shi‐kang;
Chen, Shi‐ting;
Zhan, Ying;
Guo, Xin‐yue;
Wu, Wen‐tao;
Lin, Yi‐ting;
Yu, Chang‐xi;
Yang, Jian

Publication type:

Article

Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2023, v. 133, n. 6, p. 757, doi. 10.1111/bcpt.13947

By:

Tan, Enxue;
Gao, Zhihong;
Wang, Qian;
Han, Baosheng;
Shi, Honghong;
Wang, Lihua;
Zhu, Guozhen;
Hou, Yanjuan

Publication type:

Article

The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy.

Published in:

Korean Journal of Physiology & Pharmacology, 2022, v. 26, n. 6, p. 427, doi. 10.4196/kjpp.2022.26.6.427

By:

Weichen Zhao;
Chunyuan He;
Junjie Jiang;
Zongbiao Zhao;
Hongzhong Yuan;
Facai Wang;
Bingxiang Shen

Publication type:

Article

Oxymatrine inhibits the pyroptosis in rat insulinoma cells by affecting nuclear factor kappa B and nuclear factor (erythroid-derived 2)-like 2 protein/heme oxygenase-1 pathways.

Published in:

Korean Journal of Physiology & Pharmacology, 2022, v. 26, n. 3, p. 165, doi. 10.4196/kjpp.2022.26.3.165

By:

Jingying Gao;
Lixia Xia;
Yuanyuan Wei

Publication type:

Article

MicroRNA-223-3p inhibits oxidized low-density lipoprotein-mediated NLRP3 inflammasome activation via directly targeting NLRP3 and FOXO3.

Published in:

Clinical Hemorheology & Microcirculation, 2022, v. 81, n. 3, p. 241, doi. 10.3233/CH-211232

By:

Xu, Wei;
Qian, Lei;
Yuan, Xiaoyan;
Lu, Yong

Publication type:

Article

Ameliorative Effect of D-Carvone against Hepatic Ischemia-Reperfusion-Induced Injury in Rats.

Published in:

Life (2075-1729), 2022, v. 12, n. 10, p. 1502, doi. 10.3390/life12101502

By:

Mohamed, Maged E.;
Younis, Nancy S.

Publication type:

Article

Upregulation of Nucleotide-Binding Oligomerization Domain-, LRR- and Pyrin Domain-Containing Protein 3 in Motoneurons Following Peripheral Nerve Injury in Mice.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.584184

By:

Nógrádi, Bernát;
Nyúl-Tóth, Ádám;
Kozma, Mihály;
Molnár, Kinga;
Patai, Roland;
Siklós, László;
Wilhelm, Imola;
Krizbai, István A.

Publication type:

Article

Herpes Simplex Virus 1 Induces Microglia Gasdermin D-Dependent Pyroptosis Through Activating the NLR Family Pyrin Domain Containing 3 Inflammasome.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.838808

By:

Hu, Xiao;
Zeng, Qiongzhen;
Xiao, Ji;
Qin, Shurong;
Wang, Yuan;
Shan, Tianhao;
Hu, Di;
Zhu, Yexuan;
Liu, Kaisheng;
Zheng, Kai;
Wang, Yifei;
Ren, Zhe

Publication type:

Article

Tumor necrosis factor-α blockade ameliorates diabetic nephropathy in rats.

Published in:

Clinical Kidney Journal, 2021, v. 14, p. 301, doi. 10.1093/ckj/sfz137

By:

Cheng, Dongsheng;
Liang, Rulian;
Huang, Baorui;
Hou, Jiasheng;
Yin, Jianyong;
Zhao, Ting;
Zhou, Lu;
Wu, Rui;
Qian, Youcun;
Wang, Feng

Publication type:

Article

Muckle- Wells syndrome without mutation in exon 3 of the NLRP3 gene, identified by evidence of excessive monocyte production of functional interleukin 1β and rapid response to anakinra.

Published in:

Clinical & Experimental Dermatology, 2013, v. 38, n. 8, p. 874, doi. 10.1111/ced.12186

By:

Sabroe, R. A.;
Stokes, C. A.;
Parker, L. C.;
Higgins, K.;
Prince, L. R.;
Sabroe, I.

Publication type:

Article

MEFV gene mutations in Turkish children with juvenile idiopathic arthritis.

Published in:

European Journal of Pediatrics, 2013, v. 172, n. 8, p. 1061, doi. 10.1007/s00431-013-2003-x

By:

Comak, Elif;
Dogan, Cagla;
Akman, Sema;
Koyun, Mustafa;
Gokceoglu, Arife;
Keser, Ibrahim

Publication type:

Article

Familial Mediterranean fever in Germany: epidemiological, clinical, and genetic characteristics of a pediatric population.

Published in:

European Journal of Pediatrics, 2012, v. 171, n. 12, p. 1775, doi. 10.1007/s00431-012-1803-8

By:

Lainka, E.;
Bielak, M.;
Lohse, P.;
Timmann, C.;
Stojanov, S.;
Kries, R.;
Niehues, T.;
Neudorf, U.

Publication type:

Article

Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.

Published in:

Journal of Animal Science & Biotechnology, 2024, v. 15, n. 1, p. 1, doi. 10.1186/s40104-024-01066-9

By:

Zhao, Wanli;
Shen, Taiyu;
Zhao, Bichen;
Li, Moli;
Deng, Zhaoju;
Huo, Yihui;
Aernouts, Ben;
Loor, Juan J.;
Psifidi, Androniki;
Xu, Chuang

Publication type:

Article

Gp91phox NADPH oxidase modulates litter size by regulating mucin1 in the uterus of mice.

Published in:

Systems Biology in Reproductive Medicine, 2017, v. 63, n. 2, p. 130, doi. 10.1080/19396368.2017.1282063

By:

Hiramoto, Keiichi;
Yamate, Yurika;
Sato, Eisuke F.

Publication type:

Article

Exenatide improves cisplatin induced ovarian damage through NLRP3, Nrf-2, and TLR4 pathways.

Published in:

Cirugía y Cirujanos, 2025, v. 93, n. 1, p. 35, doi. 10.24875/CIRU.23000304

By:

Doğan, Gül O.;
Erbaş, Oytun

Publication type:

Article

Francisella induced microparticulate caspase-1/gasdermin-D activation is regulated by NLRP3 independent of Pyrin.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0209931

By:

Mitra, Srabani;
Dolvin, Erin;
Krishnamurthy, Karthikeyan;
Wewers, Mark D.;
Sarkar, Anasuya

Publication type:

Article

Dopamine Activates the D1R-Zn<sup>2+</sup> Signaling Pathway to Trigger Inflammatory Response in Primary-Cultured Rat Embryonic Cortical Neurons.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 7, p. 3593, doi. 10.1007/s10571-023-01367-z

By:

Tseng, Hui-Chiun;
Pan, Chien-Yuan

Publication type:

Article

Characterization of IMG Microglial Cell Line as a Valuable In Vitro Tool for NLRP3 Inflammasome Studies.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 5, p. 2053, doi. 10.1007/s10571-022-01285-6

By:

Viil, Janeli;
Somelar-Duracz, Kelli;
Jaako, Külli;
Anier, Kaili;
Zharkovsky, Alexander

Publication type:

Article

Role of Adenosine Kinase in Sphingosine-1-Phosphate Receptor 1-Induced Mechano-Hypersensitivities.

Published in:

Cellular & Molecular Neurobiology, 2022, v. 42, n. 8, p. 2909, doi. 10.1007/s10571-021-01162-8

By:

Lauro, Filomena;
Giancotti, Luigino Antonio;
Kolar, Grant;
Harada, Caron Mitsue;
Harmon, Taylor A.;
Garrett, Timothy J.;
Salvemini, Daniela

Publication type:

Article

The role of NLRP3 and CARD8 polymorphisms in the risk of rheumatoid arthritis: A meta‐analysis of genetic association studies.

Published in:

International Journal of Rheumatic Diseases, 2023, v. 26, n. 11, p. 2214, doi. 10.1111/1756-185X.14917

By:

Lee, Young Ho;
Song, Gwan Gyu

Publication type:

Article

Familial Mediterranean fever gene mutations as a risk factor for early coronary artery disease.

Published in:

International Journal of Rheumatic Diseases, 2017, v. 20, n. 12, p. 2113, doi. 10.1111/1756-185X.12356

By:

Basar, Nurcan;
Kisacik, Bunyamin;
Ercan, Suleyman;
Pehlivan, Yavuz;
Yilmaz, Sedat;
Simsek, Ismail;
Erdem, Hakan;
Ozer, Orhan;
Pay, Salih;
Onat, Ahmet M.;
Dinc, Ayhan

Publication type:

Article

MiR-703 protects against hypoxia/reoxygenation-induced cardiomyocyte injury via inhibiting the NLRP3/caspase-1-mediated pyroptosis.

Published in:

Journal of Bioenergetics & Biomembranes, 2020, v. 52, n. 3, p. 155, doi. 10.1007/s10863-020-09832-w

By:

Wei, Xiaoliang;
Peng, Hu;
Deng, Ming;
Feng, Zongming;
Peng, Changnong;
Yang, Dahao

Publication type:

Article

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

Published in:

Nature Medicine, 2015, v. 21, n. 3, p. 248, doi. 10.1038/nm.3806

By:

Coll, Rebecca C;
Robertson, Avril A B;
Chae, Jae Jin;
Higgins, Sarah C;
Muñoz-Planillo, Raúl;
Inserra, Marco C;
Vetter, Irina;
Dungan, Lara S;
Monks, Brian G;
Stutz, Andrea;
Croker, Daniel E;
Butler, Mark S;
Haneklaus, Moritz;
Sutton, Caroline E;
Núñez, Gabriel;
Latz, Eicke;
Kastner, Daniel L;
Mills, Kingston H G;
Masters, Seth L;
Schroder, Kate

Publication type:

Article

Paclitaxel may inhibit migration and invasion of gastric cancer cells via nod‐like receptor family pyrin domain‐containing 3/caspase‐1/Gasdermin E mediated pyroptosis pathway.

Published in:

Chemical Biology & Drug Design, 2024, v. 103, n. 1, p. 1, doi. 10.1111/cbdd.14325

By:

Xu, Peng‐peng;
Wu, Jie;
Zhang, Jing;
Yu, Tian‐yue;
Wang, Yu‐bin

Publication type:

Article

Beneficial Effect of Rosuvastatin Therapy on Spleen Injury Induced by Gamma Irradiation in Rats: Targeting Nrf2/EPRE Pathway.

Published in:

Dose-Response, 2023, v. 21, n. 2, p. 1, doi. 10.1177/15593258231179900

By:

Fahim, Thanaa M.;
Mohamed, Marwa Abd EL-Hameed;
Abdelrahman, Sahar S. M.;
Lotfy, Dina M.

Publication type:

Article

The protective effect of thiolutin on doxorubicin-induced H9c2 cardiomyocyte injury.

Published in:

Journal of Toxicological Sciences, 2023, v. 48, n. 8, p. 469, doi. 10.2131/jts.48.469

By:

Wenyuan Cai;
Tingting Teng;
Xiaoyan Wang;
Baihong Li;
Xin Gu;
Yafeng Zhou

Publication type:

Article

MUC1 attenuates neutrophilic airway inflammation in asthma by reducing NLRP3 inflammasome-mediated pyroptosis through the inhibition of the TLR4/MyD88/NF-κB pathway.

Published in:

Respiratory Research, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12931-023-02550-y

By:

Liu, Lu;
Zhou, Ling;
Wang, Lingling;
Mao, Zhenyu;
Zheng, Pengdou;
Zhang, Fengqin;
Zhang, Huojun;
Liu, Huiguo

Publication type:

Article

Analysis of Signaling Pathways of Necroptotic and Pyroptotic Cell Death in the Hearts of Rats With Type 2 Diabetes Mellitus.

Published in:

Physiological Research, 2023, v. 72, p. S23, doi. 10.33549/physiolres.935020

By:

HORVÁTH, Csaba;
JARABICOVÁ, Izabela;
RAJTÍK, Tomáš;
BARTOŠOVÁ, Linda;
FERENCZYOVÁ, Kristína;
KALOČAYOVÁ, Barbora;
BARTEKOVÁ, Monika;
SZOBI, Adrián;
ADAMEOVÁ, Adriana

Publication type:

Article

NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK study.

Published in:

Immunity & Ageing, 2015, v. 12, p. 1, doi. 10.1186/s12979-015-0047-7

By:

Kunnas, Tarja;
Määttä, Kirsi;
Nikkari, Seppo T.

Publication type:

Article

The interaction of inflammasomes and gut microbiota: novel therapeutic insights.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01504-1

By:

Manshouri, Shirin;
Seif, Farhad;
Kamali, Monireh;
Bahar, Mohammad Ali;
Mashayekh, Arshideh;
Molatefi, Rasol

Publication type:

Article

P2X7 receptor activation leads to NLRP3-independent IL-1β release by human macrophages.

Published in:

Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01356-1

By:

Bockstiegel, Judith;
Engelhardt, Jonas;
Weindl, Günther

Publication type:

Article