Works matching DE "PYRIMIDINE synthesis"
Results: 373
A critical review of the reproductive safety of Leflunomide.
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- Clinical Rheumatology, 2020, v. 39, n. 2, p. 607, doi. 10.1007/s10067-019-04819-4
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High level of CTP synthase induces formation of cytoophidia in cortical neurons and impairs corticogenesis.
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- Histochemistry & Cell Biology, 2018, v. 149, n. 1, p. 61, doi. 10.1007/s00418-017-1612-2
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Synthesis and Biological Activity of 6-(1,3-Benzoxazol-2-Yl)-5-Methylthieno-[2,3-d]Pyrimidines.
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- Pharmaceutical Chemistry Journal, 2018, v. 52, n. 6, p. 510, doi. 10.1007/s11094-018-1850-1
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Synthesis and Antimicrobial Activity of 5-(Arylmethylidene)-2,4,6-Pyrimidine-2,4,6(1H,3H,5H)-Triones.
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- Pharmaceutical Chemistry Journal, 2018, v. 52, n. 6, p. 506, doi. 10.1007/s11094-018-1849-7
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Synthesis and Anticonvulsive Activity of 5-Pyrrolidin-1-Ylpyrano[4″,3″:4′,5′]Pyrido-3′,2′:4,5]Thieno[3,2- D]Pyrimidine Derivatives.
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- Pharmaceutical Chemistry Journal, 2016, v. 50, n. 4, p. 221, doi. 10.1007/s11094-016-1426-x
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Synthesis and Antimycobacterial Activity of 5-(Arylmethylene)Hexahydropyrimidine-2,4,6-Triones.
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- Pharmaceutical Chemistry Journal, 2016, v. 49, n. 12, p. 810, doi. 10.1007/s11094-016-1376-3
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Synthesis and Hypotensive Activity of Pyrimidine-2,4-(1 H,3 H)-Dione Derivatives Containing Thietane Rings with Sulfur in Various Oxidation States.
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- Pharmaceutical Chemistry Journal, 2014, v. 48, n. 7, p. 434, doi. 10.1007/s11094-014-1126-3
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Synthesis and Antioxidant Activity of 2-Thioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbamides.
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- Pharmaceutical Chemistry Journal, 2014, v. 48, n. 4, p. 246, doi. 10.1007/s11094-014-1087-6
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Synthesis and Antitumor and Antibacterial Properties of New N-Alkylated Pyrimidines.
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- Pharmaceutical Chemistry Journal, 2013, v. 47, n. 6, p. 303, doi. 10.1007/s11094-013-0948-8
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Synthesis and Neurotropic Activity of New Condensed Pyrido[3′,2′:4,5]furo[3,2- d]-pyrimidine Derivatives.
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- Pharmaceutical Chemistry Journal, 2013, v. 47, n. 3, p. 135, doi. 10.1007/s11094-013-0911-8
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Synthesis and Anticonvulsive Activity of 7-Amino-Substituted Cyclopenta[4′,5′]-pyrido[3′,2′:4,5]furo[3,2- d]pyrimidines.
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- Pharmaceutical Chemistry Journal, 2013, v. 47, n. 3, p. 130, doi. 10.1007/s11094-013-0910-9
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Synthesis and anticonvulsant activity of condensed thieno[2,3- e]pyrrolo[1,2- a]pyrimidin-8,12-diones.
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- Pharmaceutical Chemistry Journal, 2013, v. 47, n. 2, p. 92, doi. 10.1007/s11094-013-0902-9
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Antagonists of serotonin 5-HT receptors. iv. synthesis and structure-activity interactions in amines containing the 3-(arylsulfonyl)-2-(methylthio)pyrazolo[1,5- a]pyrimidine fragment.
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- Pharmaceutical Chemistry Journal, 2013, v. 46, n. 10, p. 595, doi. 10.1007/s11094-013-0853-1
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Synthesis and biological activity of new 6-benzylisocytosine derivatives: non-nucleoside HIV-1 reverse transcriptase inhibitors.
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- Pharmaceutical Chemistry Journal, 2012, v. 46, n. 7, p. 397, doi. 10.1007/s11094-012-0808-y
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Synthesis and antibacterial activity of n-(6-x-7-methyl-5-oxo-5 h-1,3,4-thiadiazolo[3,2- a]-pyrimidin-2-yl)diazo-18-crown-6.
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- Pharmaceutical Chemistry Journal, 2012, v. 45, n. 12, p. 721, doi. 10.1007/s11094-012-0710-7
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Synthesis and crystal structure analysis of two thiazolo[3,2- a]pyrimidine derivatives.
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- Journal of Structural Chemistry, 2014, v. 55, n. 7, p. 1521, doi. 10.1134/S0022476614080204
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Microwave chemistry: Synthesis of purine and pyrimidine nucleosides using microwave radiation.
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- Journal of Carbohydrate Chemistry, 2019, v. 38, n. 1, p. 20, doi. 10.1080/07328303.2018.1543430
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Synthesis of a Novel Series of ( E , E )-4,6-bis(styryl)-2- O -Glucopyranosyl-Pyrimidines and Their Potent Multidrug Resistance (MDR) Reversal Activity Against Cancer Cells.
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- Journal of Carbohydrate Chemistry, 2012, v. 31, n. 8, p. 620, doi. 10.1080/07328303.2012.689041
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Biological evaluation and synthesis of new pyrimidine-2(1H)-ol/-thiol derivatives derived from chalcones using the solid phase microwave method.
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- Turkish Journal of Chemistry, 2018, v. 42, n. 2, p. 520, doi. 10.3906/kim-1711-9
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Synthesis and biological evaluation of novel fused triazolo[4,3-a] pyrimidinones.
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- Turkish Journal of Chemistry, 2015, v. 39, n. 3, p. 510, doi. 10.3906/kim-1501-144
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Synthesis and in vivo anti-ulcer evaluation of some novel piperidine linked dihydropyrimidinone derivatives.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 978, doi. 10.1080/14756366.2018.1474212
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Synthesis and evaluation of novel spiro derivatives for pyrrolopyrimidines as anti-hyperglycemia promising compounds.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 809, doi. 10.1080/14756366.2018.1461854
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Synthesis of new pyridothienopyrimidinone and pyridothienotriazolopyrimidine derivatives as pim-1 inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 58, doi. 10.1080/14756366.2017.1389921
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Design, synthesis and biological activity of N<sup>4</sup>-phenylsubstituted-7H-pyrrolo[2,3-d]pyrimidin-4-amines as dual inhibitors of aurora kinase A and epidermal growth factor receptor kinase.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 74, doi. 10.1080/14756366.2017.1376666
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Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 1, doi. 10.1080/14756366.2016.1198901
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Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1531, doi. 10.3109/14756366.2016.1156104
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Synthesis and evaluation of 5,6-disubstituted thiopyrimidine aryl aminothiazoles as inhibitors of the calcium-activated chloride channel TMEM16A/Ano1.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1362, doi. 10.3109/14756366.2015.1135912
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Design, synthesis of novel pyranotriazolopyrimidines and evaluation of their anti-soybean lipoxygenase, anti-xanthine oxidase, and cytotoxic activities.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1277, doi. 10.3109/14756366.2015.1118684
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Synthesis of N-alkyl (aril)-tetra pyrimidine thiones and investigation of their human carbonic anhydrase I and II inhibitory effects.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1192, doi. 10.3109/14756366.2015.1113172
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Synthesis of quinolinylaminopyrimidines and quinazolinylmethylaminopyrimidines with antiproliferative activity against melanoma cell line.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 4, p. 607, doi. 10.3109/14756366.2014.958082
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The First Catalytic Direct C–H Arylation on C2 and C3 of Thiophene Ring Applied to Thieno-Pyridines, -Pyrimidines and -Pyrazines.
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- Catalysts (2073-4344), 2018, v. 8, n. 4, p. 137, doi. 10.3390/catal8040137
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Catalytic Synthesis of 3,4-dihydropyrimidin-2(1H)-ones under Green Conditions and by Keggin type Heteropolyacid catalyst H<sub>7</sub>[PM0<sub>8</sub>V<sub>4</sub>O<sub>40</sub>].
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- Gazi University Journal of Science, 2012, v. 25, n. 4, p. 823
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The stimulating influence of thienopyrimidine compounds on the adenylyl cyclase signaling systems in the rat testes.
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- Doklady Biochemistry & Biophysics, 2014, v. 456, n. 1, p. 104, doi. 10.1134/S1607672914030065
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SYNTHESIS OF PYRROLIDINES AND TETRAHYDROPYRIMIDINES VIA ONE-POT AND THREE COMPONENT CASCADE COUPLING STRATEGY IN WATER.
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- Rasayan Journal of Chemistry, 2017, v. 10, n. 1, p. 6, doi. 10.7324/RJC.2017.1011545
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Nano-basic silica as an efficient catalyst for the multi-component preparation of pyrano[2,3-d] pyrimidine derivatives.
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- Main Group Metal Chemistry, 2017, v. 40, n. 1/2, p. 19, doi. 10.1515/mgmc-2016-0034
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Synthesis, molecular docking and biological evaluation of bis-pyrimidine Schiff base derivatives.
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- Chemistry Central Journal, 2017, v. 11, n. 1, p. 1, doi. 10.1186/s13065-017-0322-0
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Utility of 2-thioxo-pyrido[2,3- d]pyrimidinone in synthesis of pyridopyrimido[2,1- b][1,3,5]-thiadiazinones and pyridopyrimido[2,1- b][1,3]thiazinones as antimicrobial agents.
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- Chemistry Central Journal, 2017, v. 11, n. 1, p. 1, doi. 10.1186/s13065-017-0286-0
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Design, synthesis and biological potentials of novel tetrahydroimidazo[1,2-a]pyrimidine derivatives.
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- Chemistry Central Journal, 2017, v. 11, n. 1, p. 1, doi. 10.1186/s13065-017-0245-9
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Pyrimidines as block units in heterocycles: novel synthesis of pyrimidines and condensed pyrimidine derivatives.
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- Journal of the Iranian Chemical Society, 2019, v. 16, n. 11, p. 2451, doi. 10.1007/s13738-019-01712-4
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Nanoparticles of manganese oxides as efficient catalyst for the synthesis of pyrano[2,3- d]pyrimidine derivatives and their complexes as potent protease inhibitors.
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- Journal of the Iranian Chemical Society, 2018, v. 15, n. 2, p. 431, doi. 10.1007/s13738-017-1244-4
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Nano-sawdust-OSOH as a new, cheap and effective nanocatalyst for one-pot synthesis of pyrano[2,3- d]pyrimidines.
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- Journal of the Iranian Chemical Society, 2015, v. 12, n. 10, p. 1801, doi. 10.1007/s13738-015-0655-3
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Heterocyclization of thiouracil derivative: synthesis of thiazolopyrimidines, tetrazolopyrimidines and triazolopyrimidines of potential biological activity.
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- Journal of the Iranian Chemical Society, 2015, v. 12, n. 10, p. 1809, doi. 10.1007/s13738-015-0656-2
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Efficient synthesis of novel imidazo[1,2-a]pyrimidine derivatives via one-pot three-component procedure.
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- Journal of the Iranian Chemical Society, 2015, v. 12, n. 6, p. 1049, doi. 10.1007/s13738-014-0564-x
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Synthesis and in vitro and in vivo antitumor/anticancer activity of novel O-Mannich bases of 4,6-diaryl-3,4-dihydropyrimidine-2(1 H)-ones.
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- Journal of the Iranian Chemical Society, 2014, v. 11, n. 6, p. 1619, doi. 10.1007/s13738-014-0438-2
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Solvent-free synthesis of polyfunctional tetrahydropyrimidines promoted by recyclable ionic liquid.
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- Journal of the Iranian Chemical Society, 2013, v. 10, n. 4, p. 695, doi. 10.1007/s13738-012-0202-4
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Microwave promoted improved regioselective synthesis of 1 H,3 H,6 H[2]benzopyrano[4,3- d]pyrimidine-2,4-diones by radical cyclisation.
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- Journal of the Iranian Chemical Society, 2013, v. 10, n. 1, p. 55, doi. 10.1007/s13738-012-0171-7
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Leflunomide is a possible deactivator for vitiligo, a pilot study.
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- Journal of the European Academy of Dermatology & Venereology, 2012, v. 26, n. 9, p. 1173, doi. 10.1111/j.1468-3083.2011.04311.x
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In vitro Activity and Safety Assessment of New Synthesized Thiazolo Pyrimidine Derivatives Augmented with Albendazole against Echinococcus Multilocularis Metacestodes in Balb/C Mice.
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- Tropical Journal of Pharmaceutical Research, 2013, v. 12, n. 6, p. 989, doi. 10.4314/tjpr.v12i6.18
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Inhibition of Pyrimidine Biosynthesis Pathway Suppresses Viral Growth through Innate Immunity.
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- PLoS Pathogens, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.ppat.1003678
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Effects of extracellular orotic acid on acute contraction-induced adaptation patterns in C2C12 cells.
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- Molecular & Cellular Biochemistry, 2018, v. 448, n. 1/2, p. 251, doi. 10.1007/s11010-018-3330-z
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