Works about PYRIMIDINE derivatives

Results: 771

Design, Synthesis, and Evaluation of Novel 2,4‐disubstituted Pyrimidine Derivatives as Double Mutant Epidermal Growth Factor Receptor‐L858R/T790M Tyrosine Kinase Inhibitors.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 1, p. 1, doi. 10.1002/jbt.70077

By:

Ahmad, Iqrar;
Patel, Harun

Publication type:

Article

Conjugate of pyrimidine derivative, the drug xymedon with succinic acid protects liver cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 3, p. 1, doi. 10.1002/jbt.22660

By:

Vyshtakalyuk, Alexandra B.;
Parfenov, Andrey A.;
Gumarova, Lilya F.;
Khasanshina, Leyla R.;
Belyaev, Grigory P.;
Nazarov, Nail G.;
Kondrashina, Darya A.;
Galyametdinova, Irina V.;
Semenov, Vyacheslav E.;
Zobov, Vladimir V.

Publication type:

Article

An Efficient Synthesis of Chromeno[2,3- d]pyrimidine-2,4-diones with a Nitroketene-Aminal Moiety at C(5) by a One-Pot Four-Component Reaction.

Published in:

Helvetica Chimica Acta, 2015, v. 98, n. 5, p. 663, doi. 10.1002/hlca.201400276

By:

Alizadeh, Abdolali;
Ghanbaripour, Rashid;
Weng Ng, Seik

Publication type:

Article

Solution and Solid-State Optical Properties of Trifluoromethylated 5-(Alkyl/aryl/heteroaryl)-2-methyl-pyrazolo[1,5- a ]pyrimidine System.

Published in:

Photochem, 2022, v. 2, n. 2, p. 345, doi. 10.3390/photochem2020024

By:

Stefanello, Felipe S.;
Vieira, Jean C. B.;
Araújo, Juliane N.;
Souza, Vitória B.;
Frizzo, Clarissa P.;
Martins, Marcos A. P.;
Zanatta, Nilo;
Iglesias, Bernardo A.;
Bonacorso, Helio G.

Publication type:

Article

In Silico Studies, Design and Synthesis of Novel Fused Pyrimidine Derivatives as a DNA Gyrase Inhibitor and Antibacterial Activity Against Quinolone Resistant Escherichia Coli.

Published in:

Journal of Computational Biophysics & Chemistry, 2023, v. 22, n. 6, p. 687, doi. 10.1142/S2737416523500357

By:

Bhandare, Richie R.;
Helina, N.;
Subramani, Arun kumar;
Natarajan, Ramalakshmi;
Mali, Suraj N.;
Shaik, Afzal B.

Publication type:

Article

QSAR and Molecular Docking of Pyrimidine Derivatives Against Plasmodium falciparum dihydrofolate reductasethymidylate synthase (PfDHFR-TS).

Published in:

Journal of Research in Pharmacy, 2022, v. 26, n. 6, p. 1723, doi. 10.29228/jrp.284

By:

TJITDA, Putra Jiwamurwa Pama;
NITBANI, Febri Odel;
MBUNGA, Dominus

Publication type:

Article

Design, synthesis, in vitro anticancer, molecular docking and SAR studies of new series of pyrrolo[2,3-d]pyrimidine derivatives.

Published in:

BMC Chemistry, 2023, v. 17, n. 1, p. 1, doi. 10.1186/s13065-023-01014-0

By:

Sroor, Farid M.;
Tohamy, Wael M.;
Zoheir, Khairy M. A.;
Abdelazeem, Nagwa M.;
Mahrous, Karima F.;
Ibrahim, Nada S.

Publication type:

Article

Synthesis and Characterization of Some Pyrimidine Derivatives from Dimethyl Malonate and Evaluation their Biological Activity.

Published in:

Diyala Journal for Pure Science, 2019, v. 15, n. 2, p. 131, doi. 10.24237/djps.15.02.494B

By:

Mahmood, Sajed Khalil;
Rasheed, Malath Khalaf

Publication type:

Article

Synthesis of novel fused acenaphtopyrimidine hybrid, its photophysical properties and HSA interaction.

Published in:

Supramolecular Chemistry, 2021, v. 33, n. 5, p. 222, doi. 10.1080/10610278.2021.1975710

By:

Yalçın, Ergin

Publication type:

Article

Experimental and computational investigations on the high binding-selectivity of pyrimidine derivatives by a pillar[5]arene.

Published in:

Supramolecular Chemistry, 2018, v. 30, n. 12, p. 977, doi. 10.1080/10610278.2018.1510123

By:

Zhang, Qian;
Li, Ke-Qing;
Yang, Jun-Hui;
Qu, Gui-Rong;
Ma, Na-Na;
Guo, Hai-Ming

Publication type:

Article

Crystal structures of two anhydrous and one hydrated 7-(arylamino)-5-methyl-2-(trifluoromethyl)-[1,2,4]-triazolo-[1,5-a] yrimidine derivatives.

Published in:

Zeitschrift für Kristallographie. Supplements, 2014, v. 229, n. 6, p. 459, doi. 10.1515/zkri-2014-1740

By:

Boechat, Núbia;
Pinheiro, Luiz C. S.;
Pinto, Angelo C.;
Silva, Thiago S.;
Wardell, James L.;
Wardell, Solange M. S. V.

Publication type:

Article

Crystal structures of two anhydrous and one hydrated 7-(arylamino)-5-methyl-2-(trifluoromethyl)-[1,2,4]-triazolo-[1,5-a]pyrimidine derivatives.

Published in:

Zeitschrift für Kristallographie. Crystalline Materials, 2014, v. 229, n. 6, p. 459, doi. 10.1515/zkri-2014-1740

By:

Boechat, Núbia;
Pinheiro, Luiz C.S.;
Pinto, Angelo C.;
Silva, Thiago S.;
Wardell, James L.;
Wardell, Solange M.S.V.

Publication type:

Article

4,6-Disubstituted pyrimidine-based microtubule affinity-regulating kinase 4 (MARK4) inhibitors: synthesis, characterization, in-vitro activity and in-silico studies.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1517504

By:

Haque, Ashanul;
Alenezi, Khalaf M.;
Rasheed, Mohd. Saeed Maulana Abdul;
Rahman, Md. Ataur;
Anwar, Saleha;
Ahamad, Shahzaib;
Gupta, Dinesh

Publication type:

Article

γ‐Fe2O3@HAp@PBABMD@Cu magnetic nanoparticles: Efficient, green, and recyclable novel nanocatalyst for the synthesis of densely functionalized pyrrole‐pyrido[2,3‐d]pyrimidine hybrids.

Published in:

Journal of the Chinese Chemical Society, 2021, v. 68, n. 5, p. 902, doi. 10.1002/jccs.202000310

By:

Saberikhah, Elham;
Mamaghani, Manouchehr;
Mahmoodi, Nosrat Ollah

Publication type:

Article

Nano CuO–Ag‐catalyzed synthesis of some novel pyrano[2,3‐d] pyrimidine derivatives and evaluation of their bioactivity.

Published in:

Journal of the Chinese Chemical Society, 2020, v. 67, n. 5, p. 805, doi. 10.1002/jccs.201900256

By:

Poola, Sreelakshmi;
Shaik, Mahammad S.;
Sudileti, Murali;
Yakkate, Subbarao;
Nalluri, Vedasree;
Chippada, Apparao;
Cirandur, Suresh R.

Publication type:

Article

Design of antimalarial agents based on pyrimidine derivatives as methionine aminopeptidase 1b inhibitor: Molecular docking, quantitative structure activity relationships, and molecular dynamics simulation studies.

Published in:

Journal of the Chinese Chemical Society, 2020, v. 67, n. 5, p. 880, doi. 10.1002/jccs.201900165

By:

Iman, Maryam;
Davood, Asghar;
Khamesipour, Ali

Publication type:

Article

Bimetallic Ru(II)–Ir(III) complexes with bridging 2,2′‐bipyrimidine: Synthesis, structures and characterization.

Published in:

Journal of the Chinese Chemical Society, 2019, v. 66, n. 3, p. 286, doi. 10.1002/jccs.201800286

By:

Zhang, Jianxin;
Liu, Yuancheng;
Yu, Pengfei

Publication type:

Article

Application of 1‐methyl imidazole‐based ionic liquid‐stabilized silica‐coated Fe3O4 as a novel modified magnetic nanocatalyst for the synthesis of pyrano[2,3‐d]pyrimidines.

Published in:

Journal of the Chinese Chemical Society, 2019, v. 66, n. 3, p. 307, doi. 10.1002/jccs.201800171

By:

Sajjadifar, Sami;
Zolfigol, Mohammad Ali;
Tami, Farzaneh

Publication type:

Article

Comparative molecular field analysis and hologram quantitative structure activity relationship studies of pyrimidine series as potent phosphodiesterase 10A inhibitors.

Published in:

Journal of the Chinese Chemical Society, 2018, v. 65, n. 11, p. 1293, doi. 10.1002/jccs.201700435

By:

Gholami Rostami, Elham;
Fatemi, Mohammad H.

Publication type:

Article

A Convenient Synthetic Method and Spectral Characterization of New Tetrahydro[1,3]oxazinothieno[2,3- c]isoquinoline and Its Pyrimidine Derivatives.

Published in:

Journal of the Chinese Chemical Society, 2017, v. 64, n. 12, p. 1417, doi. 10.1002/jccs.201700232

By:

Zaki, Remon M.;
Radwan, Shaban M.;
Kamal El-Dean, Adel M.

Publication type:

Article

Synthesis and Cytotoxicity of Some Thieno[2,3-d]pyrimidine Derivatives.

Published in:

Journal of the Chinese Chemical Society, 2017, v. 64, n. 1, p. 87, doi. 10.1002/jccs.201600279

By:

Saddik, Abdelreheem A.;
Kamal El ‐ Dean, Adel M.;
El ‐ Sokary, Gamal H.;
Hassan, Khairy M.;
Abbady, Mohamed S.;
Ismail, Ismail A.;
Saber, Saber H.

Publication type:

Article

An Expedient Synthesis of Novel Derivatives of Pyrido[2,3- d]pyrimidines Using Magnetically Supported ZrO2 Nanocatalyst.

Published in:

Journal of the Chinese Chemical Society, 2016, v. 63, n. 5, p. 410, doi. 10.1002/jccs.201500482

By:

Kheirkhah, Leila;
Mamaghani, Manouchehr;
Mahmoodi, Nosrat Ollah;
Yahyazadeh, Asieh;
Shojaei, Abdollah Fallah;
Rostamli, Yaseman

Publication type:

Article

Corrigendum: Design, Synthesis of Novel Thiourea and Pyrimidine Derivatives as Potential Antitumor Agents.

Published in:

Journal of the Chinese Chemical Society, 2015, v. 62, n. 7, p. n/a, doi. 10.1002/jccs.201590022

By:

Abu-Hashem, Ameen A.;
Badria, Farid A.

Publication type:

Article

Design, Synthesis of Novel Thiourea and Pyrimidine Derivatives as Potential Antitumor Agents.

Published in:

Journal of the Chinese Chemical Society, 2015, v. 62, n. 6, p. 506, doi. 10.1002/jccs.201400351

By:

Abu-Hashem, Ameen A.;
Badria, Farid A.

Publication type:

Article

Design and evaluation of pyrimidine derivatives as potent inhibitors of ABCG2, a breast cancer resistance protein.

Published in:

3 Biotech, 2022, v. 12, n. 9, p. 1, doi. 10.1007/s13205-022-03231-1

By:

Ahmad, Shahnawaz;
Hassan, Md. Imtaiyaz;
Gupta, Dinesh;
Dwivedi, Neeraj;
Islam, Asimul

Publication type:

Article

Microwave synthesis and antimalarial screening of novel 4-amino benzoic acid (PABA)-substituted pyrimidine derivatives as Plasmodium falciparum dihydrofolate reductase inhibitors.

Published in:

3 Biotech, 2022, v. 12, n. 8, p. 1, doi. 10.1007/s13205-022-03236-w

By:

Choudhury, Ayesha Aktar Khanam;
Vinayagam, Sathishkumar;
Adhikari, Nayana;
Ghosh, Surajit Kumar;
Sattu, Kamaraj

Publication type:

Article

New Electron‐Transporting Materials Based on Pyrimidine and Thiazolopyridine Moieties for High‐Efficiency Organic Light‐Emitting Diodes.

Published in:

Physica Status Solidi. A: Applications & Materials Science, 2024, v. 221, n. 23, p. 1, doi. 10.1002/pssa.202300889

By:

Park, Sunwoo;
Godi, Mahendra;
Khairnar, Nikita;
Kwon, Hyukmin;
Park, Sangwook;
Lee, Hayoon;
Lee, Kiho;
Park, Jongwook

Publication type:

Article

Synthesis and Pharmacological Evaluation of Substituted Thiazolopyrimidine Derivatives.

Published in:

International Journal of Pharmacy & Life Sciences, 2020, v. 11, n. 7, p. 38

By:

Kashyap, Shiv Jee;
Dudhe, Rupesh;
Singh, Gurdeep

Publication type:

Article

Synthesis and Pharmacological Evaluation of Substituted Thiazolopyrimidine Derivatives.

Published in:

International Journal of Pharmacy & Life Sciences, 2020, v. 11, n. 6, p. 38

By:

Kashyap, Shiv Jee;
Dudhe, Rupesh;
Singh, Gurdeep

Publication type:

Article

Conventional synthesis, characterization and In-vitro evaluation of 4, 6-disubstituted pyrimidine-2-one derivatives.

Published in:

International Journal of Pharmacy & Life Sciences, 2018, v. 9, n. 4, p. 5779

By:

K., Sudha Rani;
Jalasuthram, Lakshmi Durga;
Manikala, Srilatha;
Mocharla, Sravani;
Variganji, Sunand;
Banavathu, Vinod;
Lakshmi, T.

Publication type:

Article

1-calcium phosphate-uracil, a synthesized pyrimidine derivative agent, has anti-proliferative, pro-apoptotic and anti-invasion effects on multiple tumor cell lines.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 5, p. 2271, doi. 10.3892/mmr.2014.2489

By:

JING PENG;
XINLIAN CHEN;
QIAN HU;
MEI YANG;
HONGQIAN LIU;
WEI WEI;
SHANLING LIU;
HE WANG

Publication type:

Article

Pyrimidine derivatives as efficient anticorrosive agents for acid corrosion of mild steel: Electrochemical and computational validation.

Published in:

Arabian Journal of Chemistry, 2024, v. 17, n. 6, p. N.PAG, doi. 10.1016/j.arabjc.2024.105752

By:

Alamri, Aeshah H.;
Rasheeda, Kedila;
Kamal, Salwa J.;
Aljohani, Marwah;
Aljohani, Talal A.;
Baig, Irshad;
Alva, Vijaya D.P.;
Swathi, N. Phadke;
Onyeachu, Ikenna B.;
Samshuddin, Seranthimata

Publication type:

Article

Adamantane-pyrido[2,3-d]pyrimidine Derivatives; Synthesis, Characterization and Investigation of Antimicrobial Study.

Published in:

Oriental Journal of Chemistry, 2023, v. 39, n. 2, p. 393, doi. 10.13005/ojc/390219

By:

TANK, MANISHKUMAR JINABHAI;
KUCHA, NAVINKUMAR A.;
NAIK, CHIRAG G.;
BAROT, TINA R.;
MALIK, G. M.

Publication type:

Article

Synthesis and Biological Activities of some Pyrimidine derivatives: (A-Review).

Published in:

Oriental Journal of Chemistry, 2020, v. 36, n. 6, p. 1001, doi. 10.13005/ojc/360602

By:

ELKANZI, NADIA ALI AHMED

Publication type:

Article

Synthesis, Identification and Biological Activity of Some New Chalcone derivatives from 8-Chlorotheophylline.

Published in:

Oriental Journal of Chemistry, 2018, v. 34, n. 1, p. 410, doi. 10.13005/ojc/340144

By:

ABDULREDA, NABEEL A.;
ABDUL-AMEER, SALWA R.

Publication type:

Article

Synthesis and Evaluation of Acetylcholinesterase Inhibitory and Cytotoxic Activities of Pyrano[2,3-d]pyrimidines.

Published in:

Natural Product Communications, 2023, v. 18, n. 9, p. 1, doi. 10.1177/1934578X231201037

By:

Nguyen Ha Thanh;
Nguyen Thi Quynh Giang;
Nguyen Van Ha;
Hoang Thi Phuong;
Le Nhat Thuy Giang;
Nguyen Tuan Anh;
Ba Thi Cham;
Le Duc Huy;
Dang Thi Tuyet Anh;
Phan Van Kiem;
Nguyen Van Tuyen

Publication type:

Article

Antimicrobial Study against Seven Cycles Compounds Derivatives from Pyrimidine.

Published in:

Indian Journal of Forensic Medicine & Toxicology, 2020, v. 14, n. 3, p. 1515, doi. 10.37506/ijfmt.v14i3.10623

By:

Kareem, Aseel Fadhil;
Ghanim, Hasan Thamer

Publication type:

Article

Synthesis of Diimidazole Has Pyrazole, Isoxazole and Pyrimidine Derivatives and Evaluation as Antibacterial.

Published in:

Indian Journal of Forensic Medicine & Toxicology, 2020, v. 14, n. 2, p. 581, doi. 10.37506/ijfmt.v14i2.2914

By:

Kadham., Sahar Abdullah;
Atia, Abdul Jabar Kh.

Publication type:

Article

Synthesis of Diimidazole Has Pyrazole, Isoxazole and Pyrimidine Derivatives and Evaluation as Antibacterial.

Published in:

Indian Journal of Forensic Medicine & Toxicology, 2020, v. 14, n. 1, p. 1048, doi. 10.37506/v14/i1/2020/ijfmt/193044

By:

Kadham., Sahar Abdullah;
Atia, Abdul Jabar Kh.

Publication type:

Article

Synthesis of Potential Pharmaceutical Heterocycles as Surface Active Agents.

Published in:

Journal of Surfactants & Detergents, 2017, v. 20, n. 3, p. 681, doi. 10.1007/s11743-017-1936-x

By:

Howsaway, Hamida O.;
El‐Sayed, Refat

Publication type:

Article

One-pot synthesis of benzopyrano[2,3-d]pyrimidine derivatives catalyzed by LDHs@Propyl-ANDSA.

Published in:

Canadian Journal of Chemistry, 2020, v. 98, n. 5, p. 228, doi. 10.1139/cjc-2019-0481

By:

Emami-Nori, Alahyar;
Karamshahi, Zahra;
Ghorbani-Vaghei, Ramin

Publication type:

Article

Computational design of three Cu-induced triangular pyrimidines based DNA motifs with improved conductivity.

Published in:

Canadian Journal of Chemistry, 2017, v. 95, n. 5, p. 571, doi. 10.1139/cjc-2016-0595

By:

Lu, Nan;
Bu, Yuxiang

Publication type:

Article

Synthesis, Antimicrobial Evaluation and Molecular Docking Studies of Some Novel Mercapto-8-Nitro-4-Substituted [1] Benzofuro (3,2-d) Pyrimidine Derivatives.

Published in:

Indian Journal of Pharmaceutical Sciences, 2024, v. 86, n. 1, p. 253, doi. 10.36468/pharmaceutical-sciences.1272

By:

VEERAPUR, BHARATHI SHARANAPPA;
KUMAR, M.;
BASAVARAJA, K. M.

Publication type:

Article

Antioxidant Potential of Pyrimidine Derivatives against Oxidative Stress.

Published in:

2022

By:

NAIR, NISHA;
MAJEED, JASEELA;
PANDEY, P. K.;
SWEETY, RUCHI;
THAKUR, RENU

Publication type:

Literature Review

Mechanochemical Regioselective [3+3] Annulation of 6‐Amino Uracil with Propargyl Alcohols Catalyzed by a Brønsted Acid/Hexafluoroisopropanol.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 48, p. 1, doi. 10.1002/chem.202401480

By:

Yaragorla, Srinivasarao;
Sneha Latha, Dandugula;
Kumar, Rituraj

Publication type:

Article

The Boekelheide Rearrangement of Pyrimidine N‐oxides as a Case Study of Closed or Open Shell Reactions ‐ Experimental and Computational Evidence for the Participation of Radical Intermediates.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202204015

By:

Kurzawa, Timon;
Zimmer, Reinhold;
Würthwein, Ernst‐Ulrich;
Reissig, Hans‐Ulrich

Publication type:

Article

Air‐Stable Oxyallyl Patterns and a Switchable N‐Heterocyclic Carbene.

Published in:

Angewandte Chemie, 2020, v. 132, n. 28, p. 11613, doi. 10.1002/ange.202002669

By:

Tomás‐Mendivil, Eder;
Devillard, Marc;
Regnier, Vianney;
Pecaut, Jacques;
Martin, David

Publication type:

Article

Design, synthesis and herbicidal evaluation of novel 4-(1H-pyrazol-1-yl)pyrimidine derivatives.

Published in:

Oxford Bulletin of Economics & Statistics, 2015, v. 77, n. 4, p. 1189, doi. 10.1002/ps.3918

By:

Hong-Ju Ma;
Jian-Hua Zhang;
Xiang-Dong Xia;
Jing Kang;
Jian-Hong Li

Publication type:

Article

Novel HIV-1 non-nucleoside reverse transcriptase inhibitors: A combinatorial approach.

Published in:

Biochemistry (00062979), 2017, v. 82, n. 13, p. 1716, doi. 10.1134/S0006297917130107

By:

Valuev-Elliston, V.;
Kochetkov, S.

Publication type:

Article

1SYNTHESIS AND ANTIOXIDANT ACTIVITY OF NEW 2-(2-OXOINDOLINE-3-YLYDENE) SUBSTITUTED 5,6-DIHYDROIMIDAZO[2,1-b]THIAZOLONES AND 6,7-DIHYDRO-THIAZOLO[3,2-a]PYRIMIDINONES.

Published in:

Issues of Chemistry & Chemical Technology / Voprosy Khimii & Khimicheskoi Tekhnologii, 2025, n. 1, p. 71, doi. 10.32434/0321-4095-2025-158-1-71-79

By:

Slyvka, N. Yu.;
Saliyeva, L. M.;
Zhylko, V. I.;
Tkachuk, V. M.;
Vovk, M. V.

Publication type:

Article