Works matching DE "PYRIDAZINONES"

Results: 139

Development of 1,2,3‐Triazolopyridazinone Derivatives as Potential Caspase 3 and Apoptosis Inducers: Design, Synthesis and Anticancer Activity Studies.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 3, p. 1, doi. 10.1002/jbt.70216

By:

Erdemir, Guler Yagiz;
Kuruçay, Ali;
Ates, Burhan;
Altundas, Aliye

Publication type:

Article

SYNTHESIS AND ANALGESIC ACTIVITY OF 6-(M-NITROPHENYL)-4-SUBSTITUTED BENZYLIDENE-4,5- DIHYDROPYRIDAZIN-3(2H)-ONE DERIVATIVES.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2012, v. 23, n. 4, p. 254

By:

Asif, Mohammad

Publication type:

Article

Synthesis, Molecular Docking and Potential Antioxidant Activity of Di/Trisubstituted Pyridazinone Derivatives.

Published in:

Journal of the Chinese Chemical Society, 2016, v. 63, n. 9, p. 739, doi. 10.1002/jccs.201600051

By:

Khokra, Sukhbir Lal;
Khan, Shah Alam;
Thakur, Pramila;
Chowdhary, Deepika;
Ahmad, Aftab;
Husain, Asif

Publication type:

Article

Discovery of New Isoniazid Derivatives As Anti-tubercular Agents: In silico Studies, Synthesis, and In vitro Activity Evaluation.

Published in:

Oriental Journal of Chemistry, 2023, v. 39, n. 6, p. 1510, doi. 10.13005/ojc/390610

By:

MOHD, ABIDA ASH;
IMRAN, MOHD;
ALNASER, NOURA YOUSIF;
ALTIMYAT, SHAMS SAUD;
AL-OTAIBI, NAWAF M.;
BAWADEKJI, ABDULHAKIM

Publication type:

Article

MECHANIZMY ÚČINKU HERBICIDŮ A PROJEVY JEJICH PŮSOBENÍ NA ROSTLINY: Inhibitory fotosyntézy.

Published in:: Listy Cukrovarnicke a Reparske, 2010, v. 126, n. 2, p. 48
Publication type:: Article

Pyridazinones from maleic hydrazide: a new substrate for the Mitsunobu reaction.

Published in:

Canadian Journal of Chemistry, 2020, v. 98, n. 6, p. 273, doi. 10.1139/cjc-2019-0474

By:

Rodriguez, Christina;
Kiriakopoulos, Rachel;
Hiscock, Lana K.;
Schroeder, Zachary;
Dawe, Louise N.

Publication type:

Article

Comparative study of DFT/B3LYP, B3PW91, and HSEH1PBE methods applied to molecular structures and spectroscopic and electronic properties of flufenpyr and amipizone.

Published in:

Canadian Journal of Chemistry, 2015, v. 93, n. 10, p. 1147, doi. 10.1139/cjc-2015-0176

By:

Avcı, D.;
Bahçeli, S.;
Tamer, Ö.;
Atalay, Y.

Publication type:

Article

Synthesis of some heterocyclic systems of anticipated biological activities via 6-aryl-4-pyrazol-1-yl-pyridazin-3-one.

Published in:

Canadian Journal of Chemistry, 2005, v. 83, n. 3, p. 251, doi. 10.1139/v05-045

By:

Youssef, A. S. A.;
Marzouk, M. I.;
Madkour, H. M. F.;
El-Soll, A. M. A.;
El-Hashash, M. A.

Publication type:

Article

Elucidation of oxidized products of Chloridazon in advanced oxidation processes using a liquid chromatography/negative electrospray ionization tandem mass spectrometric technique.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2016, v. 30, n. 9, p. 1145, doi. 10.1002/rcm.7541

By:

Azaari, Hakima;
Chahboune, Rajae;
El Azzouzi, Mohamed;
Sarakha, Mohamed

Publication type:

Article

Direct Asymmetric α‐Selective Mannich Reaction of β,γ‐Unsaturated Ketones with Cyclic α‐Imino Ester: Divergent Synthesis of Cyclocanaline and Tetrahydro Pyridazinone Derivatives.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 16, p. 5130, doi. 10.1002/chem.202100284

By:

Geng, Yu‐Huan;
Hua, Yuan‐Zhao;
Jia, Shi‐Kun;
Wang, Min‐Can

Publication type:

Article

Norflurazon and Simazine Removal from Surface Water Using a Constructed Wetland.

Published in:

Bulletin of Environmental Contamination & Toxicology, 2011, v. 87, n. 4, p. 426, doi. 10.1007/s00128-011-0380-2

By:

Chris Wilson, P.;
Lu, Hai;
Lin, Youjian

Publication type:

Article

Synthesis and Blood Glucose Lowering Activity of Novel Benzenesulfonyl-Urea Derivatives.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2009, v. 184, n. 10, p. 2516, doi. 10.1080/10426500802467187

By:

Ahmad, Shamim;
Javed, Kalim;
Rathish, I. G.;
Bano, Sameena;
Alam, M. S.

Publication type:

Article

Pyridazine Derivative and Related Compound, Part 18: 1 Pyridazino [3′,4′:3,4] pyrazolo [5,1-c]-1,2,4-triazine-3-carboxylic Acid: Synthesis, Reactions, and Antimicrobial Activity.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2006, v. 181, n. 11, p. 2505, doi. 10.1080/10426500600754786

By:

El-Mariah, Fatma;
Hosny, Mona;
Deeb, Ali

Publication type:

Article

Pyridazine Derivatives and Related Compounds, Part 17: 1 The Synthesis of Some 3-Substituted Pyridazino[3′, 4′:3, 4]pyrazolo[5, 1- c ]-1,2,4-triazines and Their Antimicrobial Activity.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2006, v. 181, n. 4, p. 809, doi. 10.1080/10426500500272038

By:

El-Mariah, Fatma;
Hosny, Mona;
Deeb, Ali

Publication type:

Article

Pyridazine Derivatives and Related Compounds, Part 12: Synthesis of Some Pyridazino [4',3?:4,5\\Y\\eno[3,2-d\- 1,2,3-triazines.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2005, v. 180, n. 2, p. 591, doi. 10.1080/104265090517398

By:

Deeb, Ali;
Kotb, Mahmoud;
El-Abbasy, Mohamed

Publication type:

Article

Novel Synthesis of Thieno[2,3-c]Pyridazine and Pyrimido[4',5':4,5]thieno[2,3-c]pyridazine Derivatives.

Published in:

Phosphorus, Sulfur & Silicon & the Related Elements, 2005, v. 180, n. 2, p. 413, doi. 10.1080/104265090509216

By:

El-Dean, A. M. Kamal;
El-Gaby, M.S.A.;
Gaber, A. M.;
Eyada, H. A.;
Al-Kamali, A. S. N.

Publication type:

Article

The effect of SAN 9789 and light on the germination of seeds from Taraxacum vulgare.

Published in:

Physiologia Plantarum, 1983, v. 59, n. 2, p. 223, doi. 10.1111/j.1399-3054.1983.tb00762.x

By:

Widell, Karl-Olof

Publication type:

Article

Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2 H)-one as Novel Scaffold for FABP4 Inhibition.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 11, p. 1335, doi. 10.3390/ph15111335

By:

Crocetti, Letizia;
Floresta, Giuseppe;
Zagni, Chiara;
Merugu, Divya;
Mazzacuva, Francesca;
de Oliveira Silva, Renan Rodrigues;
Vergelli, Claudia;
Giovannoni, Maria Paola;
Cilibrizzi, Agostino

Publication type:

Article

Targeting Bacterial Sortases in Search of Anti-virulence Therapies with Low Risk of Resistance Development.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 5, p. 415, doi. 10.3390/ph14050415

By:

Nitulescu, Georgiana;
Margina, Denisa;
Zanfirescu, Anca;
Olaru, Octavian Tudorel;
Nitulescu, George Mihai;
Giovanna, Poce

Publication type:

Article

Synthesis, Cytotoxicity and Anti-Proliferative Activity against AGS Cells of New 3(2 H)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 3, p. 183, doi. 10.3390/ph14030183

By:

Alagöz, Mehmet Abdullah;
Özdemir, Zeynep;
Uysal, Mehtap;
Carradori, Simone;
Gallorini, Marialucia;
Ricci, Alessia;
Zara, Susi;
Mathew, Bijo;
Colotta, Vittoria

Publication type:

Article

Synthesis of new derivatives of 1-(3-aminophenyl)-4-benzoyl-5-phenyl-1H-pyrazole-3-carboxylic acid.

Published in:

Journal of the Serbian Chemical Society, 2010, v. 75, n. 12, p. 1625, doi. 10.2298/JSC101018135K

By:

KASIMOGULLARI, RAHMI;
ZENGIN, BELMA;
MADEN, MAKBULE;
MERT, SAMET;
KAZAZ, CAVIT

Publication type:

Article

Synthesis and bioevaluation of 4-chloro-2- tert-butyl-5-[2-[[1-[2-[<sup>18</sup>F]fluroethyl]-1 H-1,2,3-triazol-4-yl]methyl]phenylmethoxy]-3(2 H)-pyridazinone as potential myocardial perfusion imaging agent with PET.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2015, v. 58, n. 8, p. 349, doi. 10.1002/jlcr.3310

By:

Mou, Tiantian;
Zhao, Zuoquan;
You, Linyi;
Wang, Qian;
Fang, Wei;
Lu, Jie;
Peng, Cheng;
Zhang, Xianzhong

Publication type:

Article

Synthesis, structure, and properties of 1,3,5-triarylpyridazines.

Published in:

Chemistry of Heterocyclic Compounds, 2009, v. 45, n. 7, p. 815, doi. 10.1007/s10593-009-0354-z

By:

Potikha, L. M.;
Kovtunenko, V. A.;
Turov, A. V.

Publication type:

Article

Synthesis of Pyridazinone Derivatives.

Published in:

Chemistry of Heterocyclic Compounds, 2004, v. 40, n. 8, p. 1047, doi. 10.1023/B:COHC.0000046696.37815.62

By:

Hovakimyan, S. A.;
Babakhanyan, A. V.;
Voskanyan, V. S.;
Karapetian, V. E.;
Panosyan, G. A.;
Kocharian, S. T.

Publication type:

Article

Efficient Synthesis using One-Pot Method and In Silico Analysis of Pyridazinone Derivatives as Inhibitor for Aldose Reductase Enzymes.

Published in:

Trends in Sciences, 2025, v. 22, n. 4, p. 1, doi. 10.48048/tis.2025.9396

By:

Fatisa, Yuni;
Herfindo, Noval;
Aisyah, Fadila;
Teruna, Hilwan Yuda;
Jasril, Jasril;
Zamri, Adel;
Frimayanti, Neni

Publication type:

Article

Synthesis and Antibacterial Activity of Some Glucosyl- and Ribosyl-Pyridazin-3-ones.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2009, v. 28, n. 3, p. 184, doi. 10.1080/15257770902831011

By:

El-Sayed, H.A.;
Moustafa, A.H.;
Haikal, A.Z.;
El-Ashry, E.S. H.

Publication type:

Article

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2201407

By:

Badawi, Waleed A.;
Rashed, Mahmoud;
Nocentini, Alessio;
Bonardi, Alessandro;
Abd-Alhaseeb, Mohammad M.;
Al-Rashood, Sara T.;
Veerakanellore, Giri Babu;
Majrashi, Taghreed A.;
Elkaeed, Eslam B.;
Elgendy, Bahaa;
Gratteri, Paola;
Supuran, Claudiu T.;
Eldehna, Wagdy M.;
Elagawany, Mohamed

Publication type:

Article

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 977, doi. 10.1080/14756366.2021.1908277

By:

Abd El-Hameed, Rania H.;
Mahgoub, Shahenda;
El-Shanbaky, Hend M.;
Mohamed, Mosaad S.;
Ali, Sahar A.

Publication type:

Article

Design and synthesis of pyridazinone-substituted benzenesulphonylurea derivatives as anti-hyperglycaemic agents and inhibitors of aldose reductase – an enzyme embroiled in diabetic complications.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1415, doi. 10.3109/14756366.2016.1142986

By:

Yaseen, Raed;
Pushpalatha, H.;
Reddy, G. Bhanuprakash;
Ismael, Ameer;
Ahmed, Ayad;
Dheyaa, Alhamza;
Ovais, Syed;
Rathore, Pooja;
Samim, Mohammed;
Akthar, Mymoona;
Sharma, Kalicharan;
Shafi, Syed;
Singh, Surender;
Javed, Kalim

Publication type:

Article

Design, synthesis and antihypertensive screening of novel pyridazine substituted s-triazin-2-imine/one/thione derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 3, p. 552, doi. 10.3109/14756366.2012.656623

By:

Mishra, Ravinesh;
Siddiqui, Anees A.;
Husain, Asif;
Rashid, Mohd.;
Goda, Chirag

Publication type:

Article

On the conditions for enhanced transport through molecular junctions based on metal centres ligated by pairs of pyridazino-derived ligands.

Published in:

Molecular Physics, 2010, v. 108, n. 19/20, p. 2591, doi. 10.1080/00268976.2010.514303

By:

Bei Ding;
Washington, Victoria;
Dunietz, Barry D.

Publication type:

Article

Design, synthesis and evaluation of some novel 3(2H)-pyridazinone-2-yl acetohydrazides as acetylcholinesterase and butyrylcholnesterase inhibitors.

Published in:

Organic Communications, 2013, v. 6, n. 1, p. 55

By:

Önkol, Tijen;
Gökçe, Mehtap;
Orhan, İlkay;
Kaynak, Fatma

Publication type:

Article

Anti-Inflammatory and Antioxidant Pyrrolo[3,4- d ]pyridazinone Derivatives Interact with DNA and Bind to Plasma Proteins—Spectroscopic and In Silico Studies.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1784, doi. 10.3390/ijms25031784

By:

Kotynia, Aleksandra;
Krzyżak, Edward;
Żądło, Julia;
Witczak, Maja;
Szczukowski, Łukasz;
Mucha, Jakub;
Świątek, Piotr;
Marciniak, Aleksandra

Publication type:

Article

Exploring Three Avenues: Chemo- and Regioselective Transformations of 1,2,4-Triketone Analogs into Pyrazoles and Pyridazinones.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 14234, doi. 10.3390/ijms241814234

By:

Edilova, Yulia O.;
Osipova, Ekaterina A.;
Slepukhin, Pavel A.;
Saloutin, Victor I.;
Bazhin, Denis N.

Publication type:

Article

Targeting Lineage-Specific Transcription Factors and Cytokines of the Th17/Treg Axis by Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4- d ]pyridazinone Attenuates TNBS-Induced Experimental Colitis.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9897, doi. 10.3390/ijms23179897

By:

Szandruk-Bender, Marta;
Wiatrak, Benita;
Dzimira, Stanisław;
Merwid-Ląd, Anna;
Szczukowski, Łukasz;
Świątek, Piotr;
Szeląg, Adam

Publication type:

Article

New N -Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4- d ]pyridazinone with Significant Anti-Inflammatory Activity—Design, Synthesis and Complementary In Vitro, Computational and Spectroscopic Studies.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 20, p. 11235, doi. 10.3390/ijms222011235

By:

Szczukowski, Łukasz;
Krzyżak, Edward;
Wiatrak, Benita;
Jawień, Paulina;
Marciniak, Aleksandra;
Kotynia, Aleksandra;
Świątek, Piotr

Publication type:

Article

In Vitro and In Silico Evaluation of New 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4- d ]pyridazinone as Promising Cyclooxygenase Inhibitors.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9130, doi. 10.3390/ijms22179130

By:

Peregrym, Krzysztof;
Szczukowski, Łukasz;
Wiatrak, Benita;
Potyrak, Katarzyna;
Czyżnikowska, Żaneta;
Świątek, Piotr

Publication type:

Article

Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4- d ]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9623, doi. 10.3390/ijms21249623

By:

Szczukowski, Łukasz;
Krzyżak, Edward;
Zborowska, Adrianna;
Zając, Patrycja;
Potyrak, Katarzyna;
Peregrym, Krzysztof;
Wiatrak, Benita;
Marciniak, Aleksandra;
Świątek, Piotr

Publication type:

Article

Synthesis and Evaluation of Novel Pyrrolo[2,3-d] and Thieno[2,3-d]Pyridazinones as in Vitro Antiproliferative Agents.

Published in:

Acta Chimica Slovenica, 2009, v. 56, n. 3, p. 571

By:

Dal Piaz, Vittorio;
Vergelli, Claudia;
Giovannoni, Maria Paola;
Biancalani, Claudio;
Cilibrizzi, Agostino;
Graziano, Alessia;
Cesari, Nicoletta

Publication type:

Article

Synthesis and Characterization of Novel Compounds Derived From 6-methyl-2,6 dihydro[1,2,4-triazino[4,3-b] indazol-3(4H)-one.

Published in:

International Journal of Pharmaceutical Research (09752366), 2020, p. 1504, doi. 10.31838/ijpr/2020.SP1.233

By:

AL-SURAIFY, SAJIDA MUNADI TH.

Publication type:

Article

Levosimendan.

Published in:

2001

By:

Figgitt DP;
Gillies PS;
Goa KL

Publication type:

Journal Article

Ribosome-mediated biosynthesis of pyridazinone oligomers in vitro.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33701-2

By:

Lee, Joongoo;
Coronado, Jaime N.;
Cho, Namjin;
Lim, Jongdoo;
Hosford, Brandon M.;
Seo, Sangwon;
Kim, Do Soon;
Kofman, Camila;
Moore, Jeffrey S.;
Ellington, Andrew D.;
Anslyn, Eric V.;
Jewett, Michael C.

Publication type:

Article

Approaches towards the synthesis of a novel class of 2-amino-5-arylazonicotinate, pyridazinone and pyrido[2,3-d]pyrimidine derivatives as potent antimicrobial agents.

Published in:

Chemistry Central Journal, 2013, v. 7, n. 1, p. 1, doi. 10.1186/1752-153X-7-123

By:

Ibrahim, Hamada Mohamed;
Behbehani, Haider;
Elnagdi, Mohamed H.

Publication type:

Article

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0191984

By:

Gong, Jianhua;
Zheng, Yanbo;
Wang, Ying;
Sheng, Weijin;
Li, Yi;
Liu, Xiujun;
Si, Shuyi;
Shao, Rongguang;
Zhen, Yongsu

Publication type:

Article

Docking and quantitative structure–activity relationship of bi-cyclic heteroaromatic pyridazinone and pyrazolone derivatives as phosphodiesterase 3A (PDE3A) inhibitors.

Published in:

PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0189213

By:

Muñoz-Gutiérrez, Camila;
Cáceres-Rojas, Daniela;
Adasme-Carreño, Francisco;
Palomo, Iván;
Fuentes, Eduardo;
Caballero, Julio

Publication type:

Article

Rational Design of a Near-Infrared Fluorescent Probe Based on a Pyridazinone Scaffold.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 22, p. 3274, doi. 10.1002/ejoc.201700355

By:

Zhou, Tongliang;
Yang, Lingfei;
Liang, Lei;
Liu, Hui;
Zhu, Yuanjun;
Shui, Mengyang;
Yuan, Lan;
Xu, Fengrong;
Niu, Yan;
Wang, Chao;
Xu, Ping

Publication type:

Article

The Generation of a Library of Bromodomain-Containing Protein Modulators Expedited by Continuous Flow Synthesis.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 11, p. 2000, doi. 10.1002/ejoc.201600222

By:

Filipponi, Paolo;
Baxendale, Ian R.

Publication type:

Article

Ureido-Pyridazinone Derivatives: Insights into the Structural and Conformational Properties for STAT3 Inhibition.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 22, p. 4907, doi. 10.1002/ejoc.201500599

By:

Meneghetti, Fiorella;
Villa, Stefania;
Masciocchi, Daniela;
Barlocco, Daniela;
Toma, Lucio;
Han, Dong‐Cho;
Kwon, Byoung‐Mog;
Ogo, Naohisa;
Asai, Akira;
Legnani, Laura;
Gelain, Arianna

Publication type:

Article

Ruthenium-Catalyzed Switchable N-H/C-H Alkenylation of 6-Phenyl(dihydro)pyridazinones with Alkynes.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 31, p. 6863, doi. 10.1002/ejoc.201402986

By:

Wang, Wei;
Liang, Lei;
Xu, Fengrong;
Huang, Wenjie;
Niu, Yan;
Sun, Qi;
Xu, Ping

Publication type:

Article

Copper-Catalyzed Aerobic Dehydrogenation of C-C to C=C Bonds in the Synthesis of Pyridazinones.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 27, p. 6130, doi. 10.1002/ejoc.201300640

By:

Liang, Lei;
Yang, Guanyu;
Xu, Fengrong;
Niu, Yan;
Sun, Qi;
Xu, Ping

Publication type:

Article