Works matching DE "PURINERGIC receptors"

Results: 1740

Pedunculoside targets P2X7R to protect against myocarditis by regulating the NLRP3/PIP2/MAPK signaling pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1589298

By:

Zhuo, Youqiong;
He, Jia;
Wang, Qin-Qin;
Xiao, Yuntian;
Xie, Xiaoyun;
Liu, Lina;
Yang, Shilin;
Li, Jingjing;
Yuan, Renyikun;
Gao, Hongwei

Publication type:

Article

Synthesis and Evaluation of Anti-Inflammatory and Anti-Nociceptive Potential of Novel Acyl Hydrazone Derivatives of Ketoprofen using DFT, Virtual Screening, MD Simulation and Binding Free Energy Calculations.

Published in:

Journal of Computational Biophysics & Chemistry, 2026, v. 25, n. 3, p. 467, doi. 10.1142/S2737416525500553

By:

Zubair, Muhammad;
Waqar, Muhammad;
Khan, Ashraf Ullah;
Khattak, Aishma;
Bibi, Nadia;
Ullah, Kaleem;
Zeb, Amir;
Ullah, Amin;
Ali, Mumtaz

Publication type:

Article

Editorial: Purinergic signaling in metabolic diseases and inflammation pharmacology.

Published in:

2025

By:

Sánchez-Melgar, Alejandro;
Sanz, Juana Maria;
Giuliani, Anna Lisa

Publication type:

Editorial

Temporal Shifts in MicroRNAs Signify the Inflammatory State of Primary Murine Microglial Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5677, doi. 10.3390/ijms26125677

By:

Zohar, Keren;
Lezmi, Elyad;
Reichert, Fanny;
Eliyahu, Tsiona;
Rotshenker, Shlomo;
Weinstock, Marta;
Linial, Michal

Publication type:

Article

Diagnostic potential of P2X7, NACHT, and iL-6 as immune biomarkers in bipolar disorder.

Published in:

World Journal of Biological Psychiatry, 2025, v. 26, n. 6, p. 234, doi. 10.1080/15622975.2025.2505770

By:

Malewska-Kasprzak, Magda;
Sikorski, Magdalena;
Dmitrzak-Weglarz, Monika;
Rybakowski, Filip

Publication type:

Article

Direct Observation of ATP-Induced Conformational Changes in Single P2X4 Receptors.

Published in:

PLoS Biology, 2009, v. 7, n. 5, p. 1, doi. 10.1371/journal.pbio.1000103

By:

Shinozaki, Youichi;
Sumitomo, Koji;
Tsuda, Makoto;
Koizumi, Schuichi;
Inoue, Kazuhide;
Torimitsu, Keiichi

Publication type:

Article

Purinergic signalling during sterile liver injury.

Published in:

Liver International, 2013, v. 33, n. 3, p. 353, doi. 10.1111/liv.12109

By:

Oliveira, André G.;
Marques, Pedro E.;
Amaral, Sylvia S.;
Quintão, Jayane L. D.;
Cogliati, Bruno;
Dagli, Maria L. Z.;
Rogiers, Vera;
Vanhaecke, Tamara;
Vinken, Mathieu;
Menezes, Gustavo B.

Publication type:

Article

Development and evaluation of poly adenosine 5′‐diphosphate‐ribose polymerase 1 immobilization‐based receptor chromatography.

Published in:

Journal of Separation Science, 2021, v. 44, n. 4, p. 793, doi. 10.1002/jssc.202000856

By:

Dou, Jianwei;
Zhu, Zhongbo;
Li, Yan;
Yang, Shuo;
Guo, Zhanzi;
Li, Kangle;
Ren, Cuicui;
Huang, Linhong;
He, Jianyu

Publication type:

Article

P2Y14 receptor activation decreases interleukin-6 production and glioma GL261 cell proliferation in microglial transwell cultures.

Published in:

Journal of Neuro-Oncology, 2018, v. 137, n. 1, p. 23, doi. 10.1007/s11060-017-2700-9

By:

Curet, Marjorie A.;
Watters, Jyoti J.

Publication type:

Article

Purinergic receptors and regulatory volume decrease in seabream ( Sparus aurata) hepatocytes: a videometric study.

Published in:

Fish Physiology & Biochemistry, 2012, v. 38, n. 6, p. 1593, doi. 10.1007/s10695-012-9653-x

By:

Torre, Agata;
Trischitta, Francesca;
Faggio, Caterina

Publication type:

Article

Fetal circulating human resistin increases in diabetes during pregnancy and impairs placental mitochondrial biogenesis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00205-y

By:

Jiang, Shaoning;
Teague, April M.;
Tryggestad, Jeanie B.;
Lyons, Timothy J.;
Chernausek, Steven D.

Publication type:

Article

Blockade of P2X7 receptor‐mediated purinergic signaling with A438079 protects against LPS‐induced liver injury in rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 10, p. 1, doi. 10.1002/jbt.23443

By:

Kara, Adem;
Ozkanlar, Seckin

Publication type:

Article

Adjustments in cholinergic, adrenergic and purinergic control of cardiovascular function in snapping turtle embryos ( Chelydra serpentina) incubated in chronic hypoxia.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2014, v. 184, n. 7, p. 891, doi. 10.1007/s00360-014-0848-6

By:

Eme, John;
Rhen, Turk;
Crossley, Dane

Publication type:

Article

Aldosterone upregulates purinergic responses in larval amphibian skin epithelium.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2001, v. 171, n. 5, p. 413, doi. 10.1007/s003600100191

By:

Holbird, D.;
Jensik, P.;
Cox, T.

Publication type:

Article

Real-World Use of Novel P2Y12 Inhibitors in Patients with Acute Myocardial Infarction: A Treatment Paradox.

Published in:

Cardiology, 2016, v. 136, n. 1, p. 21, doi. 10.1159/000447396

By:

Beigel, Roy;
Iakobishvili, Zaza;
Shlomo, Nir;
Segev, amit;
Witberg, Guy;
Zahger, Doron;
atar, Shaul;
alcalai, Ronny;
Kapeliovich, Michael;
Gottlieb, Shmuel;
Goldenberg, Ilan;
asher, Elad;
Matetzky, Shlomi

Publication type:

Article

Effects of dietary cypermethrin exposure on swimming performance and expression of lipid homeostatic genes in livers of juvenile Chinook salmon, Oncorhynchus tshawytscha.

Published in:

Ecotoxicology, 2021, v. 30, n. 2, p. 257, doi. 10.1007/s10646-021-02352-2

By:

Fuller, Neil;
Magnuson, Jason T.;
Huff Hartz, Kara E.;
Fulton, Corie A.;
Whitledge, Gregory W.;
Acuña, Shawn;
Schlenk, Daniel;
Lydy, Michael J.

Publication type:

Article

The Expression of F2RL1, P2RX2, P2RX3 and P2RY2 in the Esophagus of Patients with Gastroesophageal Reflux Disease and Their Relationship to Reflux Symptoms—A Pilot Study.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 6, p. 1884, doi. 10.3390/jcm14061884

By:

Mokrowiecka, Anna;
Bartoszek, Adrian;
Fabisiak, Adam;
Wróbel, Agata;
Fichna, Jakub;
Wierzchniewska-Ławska, Agnieszka;
Jacenik, Damian;
Małecka-Wojciesko, Ewa

Publication type:

Article

The Impact of Preclinical High Potent P2Y 12 Inhibitors on Decision Making at Discharge and Clinical Outcomes in Patients with Acute Coronary Syndrome.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 12, p. 4094, doi. 10.3390/jcm12124094

By:

Hammer, Andreas;
Krammel, Mario;
Aigner, Patrick;
Pfenneberger, Georg;
Schnaubelt, Sebastian;
Hofer, Felix;
Kazem, Niema;
Koller, Lorenz;
Steinacher, Eva;
Baumer, Ulrike;
Hengstenberg, Christian;
Niessner, Alexander;
Sulzgruber, Patrick

Publication type:

Article

Radiation-Induced Salivary Gland Dysfunction: Mechanisms, Therapeutics and Future Directions.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 12, p. 4095, doi. 10.3390/jcm9124095

By:

Jasmer, Kimberly J.;
Gilman, Kristy E.;
Muñoz Forti, Kevin;
Weisman, Gary A.;
Limesand, Kirsten H.

Publication type:

Article

124 The Effect of Innate Immune Receptor Activation on Differential Breed Responses to LPS in Sheep.

Published in:

2022

By:

Johnson, Samanthia R;
Middleton, Denzel;
Bowdridge, Scott A;
Greiner, Scott P

Publication type:

Abstract

Metabolic pathways and metabolites shaping innate immunity.

Published in:

2020

By:

Kumar, Himanshu

Publication type:

Editorial

Characteristics and the role of purinergic receptors in pathophysiology with focus on immune response: Purinergic receptors are widely expressed in immune cells and regulate high variety of their functions, taking part in pathogenesis of many diseases.

Published in:

International Reviews of Immunology, 2020, v. 39, n. 3, p. 97, doi. 10.1080/08830185.2020.1723582

By:

Zyma, Marharyta;
Pawliczak, Rafał

Publication type:

Article

Molecular Targets of Oxidative Stress: Focus on the Nrf2 Signaling Pathway in Health and Disease.

Published in:

Antioxidants, 2024, v. 13, n. 3, p. 262, doi. 10.3390/antiox13030262

By:

Bonay, Marcel

Publication type:

Article

P2X7 Is Involved in the Mouse Retinal Degeneration via the Coordinated Actions in Different Retinal Cell Types.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 141, doi. 10.3390/antiox12010141

By:

Sekar, Ponarulselvam;
Hsiao, George;
Chen, Yuan-Shen;
Lin, Wan-Wan;
Chan, Chi-Ming

Publication type:

Article

Human pannexin 1 channel is not phosphorylated by Src tyrosine kinase at Tyr199 and Tyr309.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.95118

By:

Zheng Ruan;
Junuk Lee;
Yangyang Li;
Juan Du;
Wei Lü

Publication type:

Article

Maestros of anesthesia: Microglia regulate anesthesia by altering the activity of neurons in specific regions of the brain via a purinergic receptor.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.95064

By:

KHAN, ROMEESA;
RITZEL, RODNEY M.

Publication type:

Article

Soil-borne fungi alter the apoplastic purinergic signaling in plants by deregulating the homeostasis of extracellular ATP and its metabolite adenosine.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.92913

By:

Kesten, Christopher;
Leitner, Valentin;
Dora, Susanne;
Sims, James W.;
Dindas, Julian;
Zipfel, Cyril;
De Moraes, Consuelo M.;
Sanchez-Rodriguez, Clara

Publication type:

Article

Identification of a carbohydrate recognition motif of purinergic receptors.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85449

By:

Lifen Zhao;
Fangyu Wei;
Xinheng He;
Antao Dai;
Dehua Yang;
Hualiang Jiang;
Liuqing Wen;
Xi Cheng

Publication type:

Article

Endosomal trafficking of two-pore K+ efflux channel TWIK2 to plasmalemma mediates NLRP3 inflammasome activation and inflammatory injury.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.83842

By:

Long Shuang Huang;
Anas, Mohammad;
Jingsong Xu;
Bisheng Zhou;
Toth, Peter T.;
Krishnan, Yamuna;
Di, Anke;
Malik, Asrar B.

Publication type:

Article

The antagonist of P2Y11 receptor NF157 ameliorates oxidized LDL-induced vascular endothelial inflammation.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2019, v. 47, n. 1, p. 1839, doi. 10.1080/21691401.2019.1610412

By:

Kuang, Yun;
Liu, Hui;
Guo, Siyu;
Wang, Yufei;
Zhang, Huijuan;
Qiao, Yanxiang

Publication type:

Article

The activation of the purinergic system modulates the formation of foreign body giant cells in the presence of different metal alloys for clinical use.

Published in:

Journal of Osteoporosis & Mineral Metabolism / Revista de Osteoporosis y Metabolismo Mineral (Spanish edition), 2024, v. 16, n. 4, p. 123, doi. 10.20960/RevOsteoporosMetabMiner.00058

By:

Jairo Aguilera-Correa, John;
Marco-Bonilla, Miguel;
Torrecilla-Sábada, Estíbaliz;
Conde, Ana;
Ángeles Arenas, María;
José de Damborenea, Juan;
Largo, Raquel;
Herrero-Beaumont, Gabriel;
Esteban, Jaime;
Mediero, Aránzazu

Publication type:

Article

Amyloid-β-induced alteration of fast and localized calcium elevations in cultured astrocytes.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03931-7

By:

Nakata, Kaito;
Sakamoto, Joe;
Otomo, Kohei;
Sato, Masanao;
Ishii, Hirokazu;
Tsutsumi, Motosuke;
Enoki, Ryosuke;
Nemoto, Tomomi

Publication type:

Article

Serum proteomic approach to identifying differentially expressed proteins in effusive feline infectious peritonitis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03108-2

By:

Moyadee, Wassamon;
Roytrakul, Sittiruk;
Jaresitthikunchai, Janthima;
Phaonakrop, Narumon;
Choowongkomon, Kiattawee;
Ploypetch, Sekkarin;
Tansakul, Natthasit;
Rattanasrisomporn, Amonpun;
Rattanasrisomporn, Jatuporn

Publication type:

Article

Assessment of the Effect of Pyrimethamine, a Potent Inhibitor of Multidrug and Toxin Extrusion Protein 1/2K, on the Pharmacokinetics of Gefapixant (MK‐7264), a P2X3 Receptor Antagonist.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 1, p. 123, doi. 10.1002/cpdd.988

By:

Nussbaum, Jesse C.;
Hussain, Azher;
Ma, Bennett;
Min, K. Chris;
Evers, Raymond;
Li, Yun;
Garrett, Graigory;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Characterization of the purinergic receptor subtype on guinea-pig suburothelial myofibroblasts.

Published in:

BJU International, 2006, v. 97, n. 6, p. 1327, doi. 10.1111/j.1464-410X.2006.06200.x

By:

Gui-Ping Sui;
Changhao Wu;
Fry, Christopher H.

Publication type:

Article

Alterations in purinergic and cholinergic components of contractile responses of isolated detrusor contraction in a rat model of partial bladder outlet obstruction.

Published in:

BJU International, 2006, v. 97, n. 2, p. 372, doi. 10.1111/j.1464-410X.2006.06010.x

By:

Banks, Frederick C. L.;
Knight, Gillian E.;
Calvert, Robert C.;
Morgan, Robert J.;
Burnstock, Geoffrey

Publication type:

Article

Effect of chronic renal failure on the purinergic responses of corpus cavernosal smooth muscle in rabbits.

Published in:

BJU International, 2002, v. 90, n. 6, p. 596, doi. 10.1046/j.1464-410X.2002.02979.x

By:

Kilicarslan, H.;
Yildirim, S.;
Bagcivan, I.;
Ayan, S.;
Sarac, B.;
Sarioglu, Y.

Publication type:

Article

A quantitative analysis of purinoceptor expression in the bladders of patients with symptomatic outlet obstruction.

Published in:

BJU International, 2001, v. 87, n. 7, p. 617, doi. 10.1046/j.1464-410X.2001.02179.x

By:

O'Reilly, B.A.;
Kosaka, A.H.;
Chang, T.K.;
Ford, A.P.D.W.;
Popert, R.;
McMahon, S.B.

Publication type:

Article

Abstracts from the Urological Research Society Annual Scientific Meeting, 7 January 2000, Royal College of Surgeons of England, London, UK.

Published in:: 2000
Publication type:: Abstract

Optimized automated radiosynthesis of 18F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1517127

By:

Lu, Yingtong;
Cui, Yan;
Hou, Lu;
Jiang, Yuanfang;
Shang, Jingjie;
Wang, Lu;
Xu, Hao;
Ye, Weijian;
Qiu, Yang;
Guo, Bin

Publication type:

Article

Optimized automated radiosynthesis of 18F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1517127

By:

Lu, Yingtong;
Cui, Yan;
Hou, Lu;
Jiang, Yuanfang;
Shang, Jingjie;
Wang, Lu;
Xu, Hao;
Ye, Weijian;
Qiu, Yang;
Guo, Bin

Publication type:

Article

Editorial: Chronic pain: what is the mechanism?

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1496510

By:

Adams, James David;
Hsieh, Ching-Liang;
Gualdani, Roberta

Publication type:

Article

Who Is Who in Adenosine Transport.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00627

By:

Pastor-Anglada, Marçal;
Pérez-Torras, Sandra

Publication type:

Article

Fast Green FCF Alleviates Pain Hypersensitivity and Down-Regulates the Levels of Spinal P2X4 Expression and Pro-inflammatory Cytokines in a Rodent Inflammatory Pain Model.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00534

By:

Fang Xu;
Jing Yang;
Fan Lu;
Rongjun Liu;
Jinwei Zheng;
Junfang Zhang;
Wei Cui;
Chuang Wang;
Wenhua Zhou;
Qinwen Wang;
Xiaowei Chen;
Junping Chen

Publication type:

Article

Purinergic Receptors in Neurological Diseases With Motor Symptoms: Targets for Therapy.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00325

By:

Oliveira-Giacomelli, Ágatha;
Naaldijk, Yahaira;
Sardá-Arroyo, Laura;
Gonçalves, Maria C. B.;
Corrêa-Velloso, Juliana;
Pillat, Micheli M.;
de Souza, Héllio D. N.;
Ulrich, Henning

Publication type:

Article

Purinergic Ligands as Potential Therapeutic Tools for the Treatment of Inflammation-Related Intestinal Diseases.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00212

By:

Dal Ben, Diego;
Antonioli, Luca;
Lambertucci, Catia;
Fornai, Matteo;
Blandizzi, Corrado;
Volpini, Rosaria

Publication type:

Article

Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00192

By:

Svobodova, Irena;
Bhattaracharya, Anirban;
Ivetic, Milorad;
Bendova, Zdenka;
Zemkova, Hana

Publication type:

Article

The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00052

By:

Savio, Luiz E. B.;
de Andrade Mello, Paola;
da Silva, Cleide Gonçalves;
Coutinho-Silva, Robson

Publication type:

Article

Non-nucleotide Agonists Triggering P2X7 Receptor Activation and Pore Formation.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00039

By:

Di Virgilio, Francesco;
Giuliani, Anna L.;
Vultaggio-Poma, Valentina;
Falzoni, Simonetta;
Sarti, Alba C.

Publication type:

Article

Recent Advances in CNS P2X7 Physiology and Pharmacology: Focus on Neuropsychiatric Disorders.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00030

By:

Bhattacharya, Anindya

Publication type:

Article