Works about PROTEIN-tyrosine phosphatase

Results: 2160

PTPN11 in cartilage development, adult homeostasis, and diseases.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00425-0

By:

Yang, Wentian;
Lefebvre, Véronique

Publication type:

Article

Inhibition of VE-PTP rejuvenates Schlemm's canal in aged mice and acts via Tie2.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323615

By:

Mishra, Sarthak;
Ipe, Ute;
Nottebaum, Astrid F.;
Peters, Kevin G.;
Vestweber, Dietmar

Publication type:

Article

Deciphering the structural and dynamic effects of SHP2-E76 mutations: mechanistic insights into oncogenic activation.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01494-2

By:

Rafiq, Humaira;
Han, Lu;
Rehman, Ashfaq Ur;
He, Pei;
Abdelhameed, Ali Saber;
Hassan, Eman S. G.;
Fu, Hongxia;
Wadood, Abdul;
Hu, Junjian

Publication type:

Article

Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103615

By:

Qian Wang;
Hongge Li;
Yingyu Mao;
Garg, Ankur;
Eun Sil Park;
Yihua Wu;
Chow, Alyssa;
Peregrin, John;
Xin Zhang

Publication type:

Article

The effects of ondansetron on diabetes and high-fat diet-induced liver disease: a critical role for protein tyrosine phosphatase 1B.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1565628

By:

Naeem, Fawad;
Aqeel, Maryam;
Zahid, Muhammad Ammar;
Babar, Mustafeez Mujtaba;
Shah, Fawad Ali;
Agouni, Abdelali;
Malik, Sohaib Zafar

Publication type:

Article

Protein tyrosine phosphatase receptor type kappa (PTPRK) revisited: evolving insights into structure, function, and pathology.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06496-1

By:

Zheng, Chen;
Liu, Ting;
Wang, An Qi;
Chen, Xing An;
Zhang, Rong Zhe;
Wang, Xuan Chao;
Lv, Chao Yue;
Pan, Ru Lu;
Wang, Ou Chen;
Lu, Xin-Cheng

Publication type:

Article

Rare genetic variation in PTPRB is associated with central serous chorioretinopathy, varicose veins and glaucoma.

Published in:

Nature Communications, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41467-025-58686-6

By:

Rämö, Joel T.;
Gorman, Bryan R.;
Weng, Lu-Chen;
Jurgens, Sean J.;
Singhanetr, Panisa;
Tieger, Marisa G.;
van Dijk, Elon HC;
Halladay, Christopher W.;
Wang, Xin;
Hauser, Blake M.;
Kim, Soo Hyun;
Brinks, Joost;
Choi, Seung Hoan;
Luo, Yuyang;
FinnGen;
Pyarajan, Saiju;
Nealon, Cari L.;
Gorin, Michael B.;
Wu, Wen-Chih;
Anthony, Scott A.

Publication type:

Article

An Evolution-Guided Analysis Reveals a Multi-Signaling Regulation of Fas by Tyrosine Phosphorylation and its Implication in Human Cancers.

Published in:

PLoS Biology, 2016, v. 14, n. 3, p. 1, doi. 10.1371/journal.pbio.1002401

By:

Chakrabandhu, Krittalak;
Huault, Sébastien;
Durivault, Jérôme;
Lang, Kévin;
Ta Ngoc, Ly;
Bole, Angelique;
Doma, Eszter;
Dérijard, Benoit;
Gérard, Jean-Pierre;
Pierres, Michel;
Hueber, Anne-Odile

Publication type:

Article

A Novel Phosphatase Inhibitor May Be a STEP Toward Ameliorating Cognitive Dysfunction.

Published in:

PLoS Biology, 2014, v. 12, n. 8, p. 1, doi. 10.1371/journal.pbio.1001924

By:

Robinson, Richard

Publication type:

Article

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease.

Published in:

PLoS Biology, 2014, v. 12, n. 8, p. 1, doi. 10.1371/journal.pbio.1001923

By:

Xu, Jian;
Chatterjee, Manavi;
Baguley, Tyler D.;
Brouillette, Jonathan;
Kurup, Pradeep;
Ghosh, Debolina;
Kanyo, Jean;
Zhang, Yang;
Seyb, Kathleen;
Ononenyi, Chimezie;
Foscue, Ethan;
Anderson, George M.;
Gresack, Jodi;
Cuny, Gregory D.;
Glicksman, Marcie A.;
Greengard, Paul;
Lam, TuKiet T.;
Tautz, Lutz;
Nairn, Angus C.;
Ellman, Jonathan A.

Publication type:

Article

Tyrosine-Phosphorylated Caveolin-1 Blocks Bacterial Uptake by Inducing Vav2-RhoA-Mediated Cytoskeletal Rearrangements.

Published in:

PLoS Biology, 2010, v. 8, n. 8, p. 1, doi. 10.1371/journal.pbio.1000457

By:

Boettcher, Jan Peter;
Kirchner, Marieluise;
Churin, Yuri;
Kaushansky, Alexis;
Pompaiah, Malvika;
Thorn, Hans;
Brinkmann, Volker;
MacBeath, Gavin;
Meyer, Thomas F.

Publication type:

Article

Modeling T Cell Antigen Discrimination Based on Feedback Control of Digital ERK Responses.

Published in:

PLoS Biology, 2005, v. 3, n. 10, p. 1, doi. 10.1371/journal.pbio.0030356

By:

Altan-Bonnet, Grégoire;
Germain, Ronald N

Publication type:

Article

Letter to the Editor: Assignment of backbone 1H, 13C, and 15N resonances of the SH2 domain of human Grb14.

Published in:

Journal of Biomolecular NMR, 2002, v. 24, n. 3, p. 275, doi. 10.1023/A:1021612725752

By:

Scharf, Paul J.;
Lyons, Barbara A.

Publication type:

Article

Letter to the Editor: Backbone resonance assignment of the 298 amino acid catalytic domain of protein tyrosine phosphatase 1B (PTP1B).

Published in:

Journal of Biomolecular NMR, 2002, v. 24, n. 2, p. 165, doi. 10.1023/A:1020949923448

By:

Meier, Sebastian;
Li, Yu-Chin;
Koehn, James;
Vlattas, Isidoros;
Wareing, James;
Jahnke, Wolfgang;
Wennogle, Lawrence P.;
Grzesiek, Stephan

Publication type:

Article

Letter to the Editor: 1H, 15N, and 13C resonance assignments of low molecular weight human cytoplasmic protein tyrosine phosphatase-A (HCPTP-A).

Published in:

Journal of Biomolecular NMR, 2002, v. 23, n. 3, p. 251, doi. 10.1023/A:1019846106641

By:

Rastogi, Vinit K.;
Diven, Conrad F.;
Seabrook, Genevieve M.;
Genbauffe, Frank S.;
Bechard, Randy T.;
Fandl, James P.;
Peters, Kevin G.

Publication type:

Article

Proteomics of proteins associated with astaxanthin accumulation in the green algae Haematococcus lacustris under the influence of sodium orthovanadate.

Published in:

Biotechnology Letters, 2009, v. 31, n. 12, p. 1917, doi. 10.1007/s10529-009-0095-1

By:

Ngoc-Phuong Tran;
Jae-Kweon Park;
Seong-Joo Hong;
Choul-Gyun Lee

Publication type:

Article

Brap2 facilitates HsCdc14A Lys-63 linked ubiquitin modification.

Published in:

Biotechnology Letters, 2009, v. 31, n. 5, p. 615, doi. 10.1007/s10529-009-9914-7

By:

Jing-Sen Chen;
Hai-Ying Hu;
Shuo Zhang;
Min He;
Ren-Ming Hu

Publication type:

Article

Development of an automated protein-tyrosine phosphatase 1B inhibition assay and the screening of putative insulin-enhancing vanadium(IV) and zinc(II) complexes.

Published in:

Biotechnology Letters, 2005, v. 27, n. 4, p. 221, doi. 10.1007/s10529-004-7855-8

By:

Seale, Andre P.;
de Jesus, Lucia A.;
Se-Yeon Kim;
Yeon-Hong Choi;
Lim, H.B.;
Cheong-Soo Hwang;
Yang-Sun Kim

Publication type:

Article

Overexpression of PTP4A3 is associated with metastasis and unfavorable prognosis in bladder cancer.

Published in:

World Journal of Urology, 2016, v. 34, n. 6, p. 835, doi. 10.1007/s00345-015-1698-x

By:

Yeh, Hsin-Chih;
Huang, Chun-Nung;
Li, Ching-Chia;
Chang, Lin-Li;
Lin, Hui-Hui;
Ke, Hung-Lung;
Huang, A-Mei;
Liang, Peir-In;
Li, Chien-Feng;
Wu, Wen-Jeng

Publication type:

Article

Protein tyrosine phosphatase ζ enhances proliferation by increasing β-catenin nuclear expression in VHL-inactive human renal cell carcinoma cells.

Published in:

World Journal of Urology, 2013, v. 31, n. 6, p. 1547, doi. 10.1007/s00345-013-1077-4

By:

Shang, Donghao;
Xu, Xiuhong;
Wang, Daye;
Li, Yong;
Liu, Yuting

Publication type:

Article

Pancreatic autoantibodies in Italian patients with newly diagnosed type 1 diabetes mellitus over the age of 20 years.

Published in:

Acta Diabetologica, 2006, v. 43, n. 3, p. 79, doi. 10.1007/s00592-006-0217-3

By:

Betterle, C.;
Lazzarotto, F.;
Fusari, A.;
Zanchetta, R.;
Benedini, S.;
Pedini, B.;
Moscon, A.;
Presotto, F.

Publication type:

Article

Prediction of substrate sites for protein phosphatases 1B, SHP-1, and SHP-2 based on sequence features.

Published in:

Amino Acids, 2014, v. 46, n. 8, p. 1919, doi. 10.1007/s00726-014-1739-6

By:

Wu, Zheng;
Lu, Ming;
Li, Tingting

Publication type:

Article

Regulation of taurine homeostasis by protein kinase CK2 in mouse fibroblasts.

Published in:

Amino Acids, 2011, v. 40, n. 4, p. 1091, doi. 10.1007/s00726-010-0732-y

By:

Hansen, Daniel;
Guerra, Barbara;
Jacobsen, Jack;
Lambert, Ian

Publication type:

Article

Focus on phosphohistidine.

Published in:

Amino Acids, 2007, v. 32, n. 1, p. 145, doi. 10.1007/s00726-006-0443-6

By:

P. V. Attwood;
M. J. Piggott;
X. L. Zu;
P. G. Besant

Publication type:

Article

A family of proteins that inhibit signalling through tyrosine kinase receptors.

Published in:

Nature, 1997, v. 386, n. 6621, p. 181, doi. 10.1038/386181a0

By:

Kharitonenkov, Alexei;
Chen, Zhengjun

Publication type:

Article

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor.

Published in:

Biochemical Journal, 2025, v. 482, n. 7, p. 341, doi. 10.1042/BCJ20240626

By:

Qinglin Li;
Yunpeng Bai;
Cavender, Sarah M.;
Yiming Miao;
Meke, Frederick Nguele;
Lasse-Opsahl, Emily L.;
Peipei Zhu;
Doody, Gina M.;
Tao, W. Andy;
Zhong-Yin Zhang

Publication type:

Article

Acute Administration of Imipramine and Citalopram Increases Activity of Striatal-Enriched Tyrosine Protein Phosphatase (STEP) in Brain of Zebrafish Danio rerio.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 170, n. 5, p. 627, doi. 10.1007/s10517-021-05120-8

By:

Kulikova, E. A.;
Bazovkina, D. V.;
Evsyukova, V. S.;
Kulikov, A. V.

Publication type:

Article

Study on the mechanisms of an extract ofSalvia miltiorrhiza on the regulation of permeability of endothelial cells exposed to tumour necrosis factor-α.

Published in:

Journal of Pharmacy & Pharmacology, 2007, v. 59, n. 7, p. 1027, doi. 10.1211/jpp.59.7.0016

By:

Mei Ding;
Ying-Jin Yuan

Publication type:

Article

Evaluation of Protein Tyrosine Phosphatase Nonreceptor Type 22 gene polymorphism in alopecia areata.

Published in:

Zagazig University Medical Journal, 2024, v. 30, p. 11, doi. 10.21608/ZUMJ.2022.162081.2642

By:

El-Din Abdelhady, Asmaa Diaa;
Abd Allah, Somaia H.;
Nassar, Amany;
Talaat, Aliaa

Publication type:

Article

The inflammatory APRIL (a proliferation-inducing ligand) antagonizes chondroitin sulphate proteoglycans to promote axonal growth and myelination.

Published in:

Brain Communications, 2025, v. 7, n. 1, p. 1, doi. 10.1093/braincomms/fcae473

By:

Ahmed, Mashal Claude;
Kakunuri, Tejaswini;
Peris, Leticia;
Meffre, Delphine;
Yilmaz, Elif Nur;
Grewing, Laureen;
González, Raquel Guerrero;
Manfroi, Benoit;
Gout, Evelyne;
Vivès, Romain R;
Fitzgerald, Una;
Schneider, Pascal;
Jafarian-Tehrani, Mehrnaz;
Kuhlmann, Tanja;
Huard, Bertrand

Publication type:

Article

Identification and functional verification of the target protein of pedunsaponin A in the gills of Pomacea canaliculata.

Published in:

Pest Management Science, 2022, v. 78, n. 3, p. 947, doi. 10.1002/ps.6704

By:

Yang, Chunping;
Ma, Yuqing;
Wang, Bin;
Wang, Yanmei;
Liu, Jingxiang;
Jiang, Chunxian;
Zhang, Min;
Qiu, Xiaoyan;
Luo, Liya;
Chen, Huabao

Publication type:

Article

Aberrant Expression of PTPN-14 and Wilms’ Tumor 1 as Putative Biomarker for Locoregional Recurrence in Oral Squamous Cell Carcinoma.

Published in:

Asian Journal of Oncology, 2022, v. 8, n. 1, p. 29, doi. 10.1055/s-0041-1731128

By:

Nayak, Seema;
Brahma Bhatt, Madan Lal;
Goel, Madhu Mati;
Gupta, Seema;
Mehrotra, Divya;
Mahdi, Abbas Ali;
Mishra, Anupam

Publication type:

Article

SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00486-6

By:

Lai, Xianning;
Lui, Sarah Kit Leng;
Lam, Hiu Yan;
Adachi, Yuta;
Sim, Wen Jing;
Vasilevski, Natali;
Armstrong, Nicola J.;
Bridgeman, Stephanie Claire;
Main, Nathan Michael;
Tan, Tuan Zea;
Tirnitz-Parker, Janina E. E.;
Thiery, Jean Paul;
Ebi, Hiromichi;
Kumar, Alan Prem;
Eichhorn, Pieter Johan Adam

Publication type:

Article

The isoflavonoid calycosin inhibits inflammation and enhances beta cell function in gestational diabetes mellitus by suppressing RNF38 expression.

Published in:

Immunopharmacology & Immunotoxicology, 2020, v. 42, n. 4, p. 366, doi. 10.1080/08923973.2020.1782426

By:

Li, Yuan;
Duan, Bide;
Li, Ying;
Yu, Shujun;
Wang, Yanyun

Publication type:

Article

Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with unexplained recurrent pregnancy loss: A case-control study.

Published in:

International Journal of Reproductive Biomedicine, 2021, v. 19, n. 10, p. 873, doi. 10.18502/ijrm.v19i10.9819

By:

Khanbarari, Fateme;
Ghasemi, Nasrin;
Vakili, Mahmood;
Samadi, Morteza

Publication type:

Article

PTP4A1 promotes oral squamous cell carcinoma (OSCC) metastasis through altered mitochondrial metabolic reprogramming.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01657-x

By:

Liu, Bing;
Si, Wen;
Wei, Bo;
Zhang, Xuan;
Chen, Peng

Publication type:

Article

An incomplete LEOPARD syndrome presented with generalized lentigines.

Published in:

2024

By:

Wang, Tianzi;
Lin, Yan;
Sun, Lele;
Mao, Lingyu;
Gao, Xiaoyuan;
Liu, Xiaodong;
Liu, Huaxu

Publication type:

Case Study

Molecular docking and high throughput screening of designed potent inhibitor to PTPN11 involved in Peptic Ulcer.

Published in:

South Asian Journal of Experimental Biology, 2016, v. 6, n. 4, p. 124, doi. 10.38150/sajeb.6(4).p124-130

By:

Sahu, Mahadev;
Sultan, Armiya;
Barik, Manas Ranjan

Publication type:

Article

Synthesis and Anti-hyperglycaemic Study of Aryl Sulfonate Ester Conjugated 5-arylidene-thiazolidine-2,4-diones.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2021, v. 55, n. 3, p. 894, doi. 10.5530/ijper.55.3.164

By:

Mehta, Mukul;
Mahapatra, Manoj Kumar

Publication type:

Article

Structural, Spectral, Molecular Docking, and Molecular Dynamics Simulations of Phenylthiophene-2-Carboxylate Compounds as Potential Anticancer Agents.

Published in:

Polycyclic Aromatic Compounds, 2024, v. 44, n. 1, p. 238, doi. 10.1080/10406638.2023.2172052

By:

Vennila, P.;
Al-Otaibi, Jamelah S.;
Venkatesh, G.;
Sheena Mary, Y.;
Raj, V.;
Acharjee, Nivedita;
Tamilselvi, P.

Publication type:

Article

Electron paramagnetic resonance (EPR) spectroscopy of the stable-free radical in the native metallo-cofactor of the manganese-ribonucleotide reductase (Mn-RNR) of Corynebacterium glutamicum.

Published in:

Free Radical Research, 2009, v. 43, n. 10, p. 943, doi. 10.1080/10715760903140568

By:

Abbouni, Bouziane;
Oehlmann, Wulf;
Stolle, Patrick;
Pierik, Antonio J.;
Auling, Georg

Publication type:

Article

Deferoxamine synergistically enhances iron-mediated AP-1 activation: A showcase of the interplay between extracellular-signal-regulated kinase and tyrosine phosphatase.

Published in:

Free Radical Research, 2007, v. 41, n. 10, p. 1135, doi. 10.1080/10715760701609061

By:

Huang, Xi;
Dai, Jisen;
Huang, Chuanshu;
Zhang, Qi;
Bhanot, Opinder;
Pelle, Edward

Publication type:

Article

Down-regulation of SHP2 promotes neutrophil autophagy and inhibits neutrophil extracellular trap formation to alleviate asthma through the ERK5 pathway.

Published in:

Central European Journal of Immunology, 2024, v. 49, n. 3, p. 252, doi. 10.5114/ceji.2024.143691

By:

Shi, Dandan;
Huang, Jian;
Wu, Jie

Publication type:

Article

Molecular regulatory mechanism of LILRB4 in the immune response.

Published in:

Central European Journal of Immunology, 2023, v. 48, n. 1, p. 43, doi. 10.5114/ceji.2023.125238

By:

HAIYIN LIU;
JUN YANG;
JING ZHANG;
PEIYUE ZHANG;
MENGTING ZHANG;
CHAOJUN YANG;
LI LIU;
CUIYUAN HUANG;
WEI WANG;
YUHONG ZHAI;
JIAN YANG

Publication type:

Article

In planta Production and Validation of Neuraminidase Derived from Genotype 4 Reassortant Eurasian Avian-like H1N1 Virus as a Vaccine Candidate.

Published in:

Plants (2223-7747), 2022, v. 11, n. 21, p. 2984, doi. 10.3390/plants11212984

By:

Kim, Da Been;
Lee, Sun Min;
Geem, Kyoung Rok;
Kim, Jitae;
Kim, Eui Ho;
Lee, Dong Wook

Publication type:

Article

Placenta microRNA profile of patient with Obstetric Antiphospholipid Syndrome.

Published in:

Malaysian Journal of Pathology, 2023, v. 45, n. 3, p. 425

By:

MOHAMAD, Muhammad Aliff;
AHMAD ASNAWI, Asral Wirda;
SUHIMAN, Muhammad Shazwan;
SATHAR, Jameela;
HAYATI, Abdul Rahman;
ABDUL RAHIM, Nur Syahrina;
MASRI, Maizatul Azma;
ABDUL HAMID, Nazefah;
NURUL FARIHAH, Samsudin;
MOHAMAD NOR, Nadeeya;
NUR FARIHA, Mohd Manzor

Publication type:

Article

Comprehensive protein tyrosine phosphatase mRNA profiling identifies new regulators in the progression of glioma.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0372-x

By:

Bourgonje, Annika M.;
Verrijp, Kiek;
Schepens, Jan T. G.;
Navis, Anna C.;
Piepers, Jolanda A. F.;
Palmen, Chantal B. C.;
van den Eijnden, Monique;
van Huijsduijnen, Rob Hooft;
Wesseling, Pieter;
Leenders, William P. J.;
Hendriks, Wiljan J. A. J.

Publication type:

Article

Molecular Dynamics Simulations on the Free and Complexed N-Terminal SH2 Domain of SHP-2.

Published in:

In Silico Biology, 2002, v. 2, n. 3, p. 305

By:

Wieligmann, Karin;
De Castro, Luis Felipe Pineda;
Zacharias, Martin

Publication type:

Article

Modulation of erythrocyte deformability by PKC activity.

Published in:

Clinical Hemorheology & Microcirculation, 2008, v. 39, n. 1-4, p. 363, doi. 10.3233/CH-2008-1101

By:

De Oliveira, Sofia;
Silva-Herdade, Ana S.;
Saldanha, Carlota

Publication type:

Article

Aberrant DNA methylation of PTPRG as one possible mechanism of its under‐expression in CML patients in the State of Qatar.

Published in:

Molecular Genetics & Genomic Medicine, 2020, v. 8, n. 10, p. 1, doi. 10.1002/mgg3.1319

By:

Ismail, Mohamed A.;
Samara, Muthanna;
Al Sayab, Ali;
Alsharshani, Mohamed;
Yassin, Mohamed A.;
Varadharaj, Govindarajulu;
Vezzalini, Marzia;
Tomasello, Luisa;
Monne, Maria;
Morsi, Hisham;
Qoronfleh, M. Walid;
Zayed, Hatem;
Cook, Richard;
Sorio, Claudio;
Modjtahedi, Helmout;
Al‐Dewik, Nader I.

Publication type:

Article