Works matching DE "PROTEIN-tyrosine phosphatase"

Results: 2165

PTPRC Knockdown Inhibits Inflammation in Gouty Arthritis by Blocking the JAK2/STAT3 Signaling Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 6, p. 1, doi. 10.1002/jbt.70340

By:

Mo, Hong;
Li, Fengxia;
Zheng, Zhongying;
Ma, Zongbo;
Liu, Shuyue;
Wen, Lian;
Su, Xubo

Publication type:

Article

Watercress-derived glucosinolates as potential allosteric PTP1B inhibitors: a dual in silico and in vitro study on insulin signaling modulation.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01544-9

By:

Ahmed, Noha A.;
Allam, Ahmed A.;
Rudayni, Hassan A.;
Alshabrmi, Fahad M.;
Alkhayl, Faris F. Aba;
Abdelrheem, Doaa A.;
Lamsabhi, Al Mokhtar;
Othman, Sarah I.;
Kamel, Emadeldin M.

Publication type:

Article

Functional Characterization of MIP_07528 of Mycobacterium indicus pranii for Tyrosine Phosphatase Activity Displays Sensitivity to Oxidative Inactivation and Plays a Role in Immunomodulation.

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Biology (2079-7737), 2025, v. 14, n. 5, p. 565, doi. 10.3390/biology14050565

By:

Raunak, Raunak;
Rakshit, Roopshali;
Bahl, Aayush;
Sinha, Soumya;
Pandey, Saurabh;
Kant, Sashi;
Tripathi, Deeksha

Publication type:

Article

Significance of Midkine Signaling in Women's Cancers: Novel Biomarker and Therapeutic Target.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4809, doi. 10.3390/ijms26104809

By:

Aller, Emily J.;
Nair, Hareesh B.;
Vadlamudi, Ratna K.;
Viswanadhapalli, Suryavathi

Publication type:

Article

PTEN is a protein tyrosine phosphatase for IRS1.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 6, p. 522, doi. 10.1038/nsmb.2828

By:

Shi, Yuji;
Wang, Junru;
Chandarlapaty, Sarat;
Cross, Justin;
Thompson, Craig;
Rosen, Neal;
Jiang, Xuejun

Publication type:

Article

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 443, doi. 10.1038/nsmb.2807

By:

Wallweber, Heidi J A;
Tam, Christine;
Franke, Yvonne;
Starovasnik, Melissa A;
Lupardus, Patrick J

Publication type:

Article

Grb-ing hold of insulin signaling.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 8, p. 803, doi. 10.1038/nsmb0809-803

By:

Ceccarelli, Derek F. J.;
Sicheri, Frank

Publication type:

Article

Protein tyrosine phosphatase non-receptor type 14 is a novel sperm-motility biomarker.

Published in:

Journal of Assisted Reproduction & Genetics, 2011, v. 28, n. 9, p. 851, doi. 10.1007/s10815-011-9602-0

By:

Chao, Hsin-Chih;
Chung, Chia-Ling;
Pan, Hsien-An;
Liao, Pao-Chi;
Kuo, Pao-Lin;
Hsu, Chao-Chin

Publication type:

Article

Immunohistochemical examination of anti-inflammatory and anti-apoptotic effects of hesperetin on trinitrobenzene sulfonic acid induced colitis in rats.

Published in:

Biotechnic & Histochemistry, 2019, v. 94, n. 3, p. 151, doi. 10.1080/10520295.2018.1530454

By:

Polat, F. R.;
Karaboğa, İ.

Publication type:

Article

The Effect of Traumatic Acid on Tyrosine Phosphorylation of Proteins in Pea Seedlings.

Published in:

Doklady Biochemistry & Biophysics, 2005, v. 405, n. 1-6, p. 426, doi. 10.1007/s10628-005-0131-6

By:

Asafova, E. V.;
Asaleeva, G. A.;
Yakovleva, V. G.;
Tarchevskii, I. A.

Publication type:

Article

Using Peptide Arrays to Profile Phosphatase Activity in Cell Lysates.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 1, p. 165, doi. 10.1002/chem.201904364

By:

Szymczak, Lindsey C.;
Sykora, Daniel J.;
Mrksich, Milan

Publication type:

Article

The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases.

Published in:

BioMetals, 2015, v. 28, n. 6, p. 975, doi. 10.1007/s10534-015-9882-4

By:

Kuban-Jankowska, Alicja;
Gorska, Magdalena;
Jaremko, Lukasz;
Jaremko, Mariusz;
Tuszynski, Jack;
Wozniak, Michal

Publication type:

Article

Inhibitory zinc sites in enzymes.

Published in:

BioMetals, 2013, v. 26, n. 2, p. 197, doi. 10.1007/s10534-013-9613-7

By:

Maret, Wolfgang

Publication type:

Article

Application of Zinpyr-1 for the investigation of zinc signals in Escherichia coli.

Published in:

BioMetals, 2013, v. 26, n. 1, p. 167, doi. 10.1007/s10534-012-9604-0

By:

Haase, Hajo;
Hebel, Silke;
Engelhardt, Gabriela;
Rink, Lothar

Publication type:

Article

Exploration of biguanido-oxovanadium complexes as potent and selective inhibitors of protein tyrosine phosphatases.

Published in:

BioMetals, 2012, v. 25, n. 3, p. 599, doi. 10.1007/s10534-012-9548-4

By:

Lu, Liping;
Gao, Xiaoli;
Zhu, Miaoli;
Wang, Sulian;
Wu, Qiong;
Xing, Shu;
Fu, Xueqi;
Liu, Zhiwei;
Guo, Maolin

Publication type:

Article

Inhibition protein tyrosine phosphatases by an oxovanadium glutamate complex, Na[VO(Glu)(CHOH)](Glu = glutamate).

Published in:

BioMetals, 2010, v. 23, n. 6, p. 1139, doi. 10.1007/s10534-010-9363-8

By:

Lu, Liping;
Wang, Sulian;
Zhu, Miaoli;
Liu, Zhiwei;
Guo, Maolin;
Xing, Shu;
Fu, Xueqi

Publication type:

Article

Crystallographic landscape of SHP2 provides molecular insights for SHP2 targeted drug discovery.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 5, p. 1781, doi. 10.1002/med.21890

By:

Song, Yihui;
Yang, Xinyu;
Wang, Shu;
Zhao, Min;
Yu, Bin

Publication type:

Article

Recent advances in the development of allosteric protein tyrosine phosphatase inhibitors for drug discovery.

Published in:

Medicinal Research Reviews, 2022, v. 42, n. 3, p. 1064, doi. 10.1002/med.21871

By:

Elhassan, Reham M.;
Hou, Xuben;
Fang, Hao

Publication type:

Article

Mechanisms of mGluR‐dependent plasticity in hippocampal area CA2.

Published in:

Hippocampus, 2023, v. 33, n. 6, p. 730, doi. 10.1002/hipo.23529

By:

Samadi, Mahsa;
Hales, Claire A.;
Lustberg, Daniel J.;
Farris, Shannon;
Ross, Madeleine R.;
Zhao, Meilan;
Hepler, John R.;
Harbin, Nicholas H.;
Robinson, Emma S. J.;
Banks, Paul J.;
Bashir, Zafar I.;
Dudek, Serena M.

Publication type:

Article

Pleiotrophin increases neurite length and number of spiral ganglion neurons in vitro.

Published in:

Experimental Brain Research, 2019, v. 237, n. 11, p. 2983, doi. 10.1007/s00221-019-05644-6

By:

Bertram, Sebastian;
Roll, Lars;
Reinhard, Jacqueline;
Groß, Katharina;
Dazert, Stefan;
Faissner, Andreas;
Volkenstein, Stefan

Publication type:

Article

Stereospecificity of myo-inositol hexakisphosphate hydrolysis by a protein tyrosine phosphatase-like inositol polyphosphatase from Megasphaera elsdenii.

Published in:

Applied Microbiology & Biotechnology, 2009, v. 82, n. 1, p. 95, doi. 10.1007/s00253-008-1734-5

By:

Puhl, Aaron;
Greiner, Ralf;
Selinger, L.

Publication type:

Article

Focus on O-phosphohydroxylysine, O-phosphohydroxyproline, N -phosphotryptophan and S-phosphocysteine.

Published in:

Amino Acids, 2017, v. 49, n. 8, p. 1309, doi. 10.1007/s00726-017-2446-x

By:

Piggott, Matthew;
Attwood, Paul

Publication type:

Article

Prediction of substrate sites for protein phosphatases 1B, SHP-1, and SHP-2 based on sequence features.

Published in:

Amino Acids, 2014, v. 46, n. 8, p. 1919, doi. 10.1007/s00726-014-1739-6

By:

Wu, Zheng;
Lu, Ming;
Li, Tingting

Publication type:

Article

Regulation of taurine homeostasis by protein kinase CK2 in mouse fibroblasts.

Published in:

Amino Acids, 2011, v. 40, n. 4, p. 1091, doi. 10.1007/s00726-010-0732-y

By:

Hansen, Daniel;
Guerra, Barbara;
Jacobsen, Jack;
Lambert, Ian

Publication type:

Article

Focus on phosphohistidine.

Published in:

Amino Acids, 2007, v. 32, n. 1, p. 145, doi. 10.1007/s00726-006-0443-6

By:

P. V. Attwood;
M. J. Piggott;
X. L. Zu;
P. G. Besant

Publication type:

Article

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor.

Published in:

Biochemical Journal, 2025, v. 482, n. 7, p. 341, doi. 10.1042/BCJ20240626

By:

Qinglin Li;
Yunpeng Bai;
Cavender, Sarah M.;
Yiming Miao;
Meke, Frederick Nguele;
Lasse-Opsahl, Emily L.;
Peipei Zhu;
Doody, Gina M.;
Tao, W. Andy;
Zhong-Yin Zhang

Publication type:

Article

Evaluation of Protein Tyrosine Phosphatase Nonreceptor Type 22 gene polymorphism in alopecia areata.

Published in:

Zagazig University Medical Journal, 2024, v. 30, p. 11, doi. 10.21608/ZUMJ.2022.162081.2642

By:

El-Din Abdelhady, Asmaa Diaa;
Abd Allah, Somaia H.;
Nassar, Amany;
Talaat, Aliaa

Publication type:

Article

Tyrosine phosphatase SHP2 promoted the progression of CRC via modulating the PI3K/BRD4/TFEB signaling induced ferroptosis.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01586-w

By:

Chen, Jian;
Li, Wei;
Zhang, Cheng;
Wen, Dihao;
Jiao, Cheng

Publication type:

Article

WWP1 inhibition increases SHP2 inhibitor efficacy in colorectal cancer.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00650-6

By:

Fan, Hao;
Hu, Xuefei;
Cao, Fuao;
Zhou, Leqi;
Wen, Rongbo;
Shen, Hao;
Fu, Yating;
Zhu, Xiaoming;
Jia, Hang;
Liu, Zixuan;
Wang, Guimin;
Yu, Guanyu;
Chang, Wenjun;
Zhang, Wei

Publication type:

Article

SHP2 inhibitors maintain TGFβ signalling through SMURF2 inhibition.

Published in:

NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00486-6

By:

Lai, Xianning;
Lui, Sarah Kit Leng;
Lam, Hiu Yan;
Adachi, Yuta;
Sim, Wen Jing;
Vasilevski, Natali;
Armstrong, Nicola J.;
Bridgeman, Stephanie Claire;
Main, Nathan Michael;
Tan, Tuan Zea;
Tirnitz-Parker, Janina E. E.;
Thiery, Jean Paul;
Ebi, Hiromichi;
Kumar, Alan Prem;
Eichhorn, Pieter Johan Adam

Publication type:

Article

SALM4 negatively regulates NMDA receptor function and fear memory consolidation.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02656-3

By:

Lie, Eunkyung;
Yeo, Yeji;
Lee, Eun-Jae;
Shin, Wangyong;
Kim, Kyungdeok;
Han, Kyung Ah;
Yang, Esther;
Choi, Tae-Yong;
Bae, Mihyun;
Lee, Suho;
Um, Seung Min;
Choi, Se-Young;
Kim, Hyun;
Ko, Jaewon;
Kim, Eunjoon

Publication type:

Article

Inflammation: IL-1α comes to the fore.

Published in:

Nature Reviews Immunology, 2013, v. 13, n. 7, p. 470, doi. 10.1038/nri3482

By:

Papatriantafyllou, Maria

Publication type:

Article

In Brief.

Published in:: Nature Reviews Immunology, 2005, v. 5, n. 3, p. 185, doi. 10.1038/nri1582
Publication type:: Article

Protein tyrosine phosphatases and the immune response.

Published in:

Nature Reviews Immunology, 2005, v. 5, n. 1, p. 43, doi. 10.1038/nri1530

By:

Mustelin, Tomas;
Vang, Torkel;
Bottini, Nunzio

Publication type:

Article

T-cell signalling: Giving T cells a PEP talk.

Published in:

Nature Reviews Immunology, 2004, v. 4, n. 3, p. 165, doi. 10.1038/nri1315

By:

Minton, Kirsty

Publication type:

Article

Anti-Inflammatory and Anti-Thrombogenic Properties of Arterial Elastic Laminae.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 4, p. 424, doi. 10.3390/bioengineering10040424

By:

Goldman, Jeremy;
Liu, Shu Q.;
Tefft, Brandon J.

Publication type:

Article

151. METABOLISM OF ERTIPROTAFIB IN MICE, RATS AND DOGS AFTER ORAL ADMINISTRATION.

Published in:: 2002
Publication type:: Abstract

Targeting Tyrosine Phosphatases by 3-Bromopyruvate Overcomes Hyperactivation of Platelets from Gastrointestinal Cancer Patients.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 7, p. 936, doi. 10.3390/jcm8070936

By:

Faria, Alessandra V. S.;
Andrade, Sheila S.;
Reijm, Agnes N.;
Spaander, Manon C. W.;
de Maat, Moniek P. M.;
Peppelenbosch, Maikel P.;
Ferreira-Halder, Carmen V.;
Fuhler, Gwenny M.

Publication type:

Article

In planta Production and Validation of Neuraminidase Derived from Genotype 4 Reassortant Eurasian Avian-like H1N1 Virus as a Vaccine Candidate.

Published in:

Plants (2223-7747), 2022, v. 11, n. 21, p. 2984, doi. 10.3390/plants11212984

By:

Kim, Da Been;
Lee, Sun Min;
Geem, Kyoung Rok;
Kim, Jitae;
Kim, Eui Ho;
Lee, Dong Wook

Publication type:

Article

Ustilaginoidea virens secretes a family of phosphatases that stabilize the negative immune regulator OsMPK6 and suppress plant immunity.

Published in:

Plant Cell, 2022, v. 34, n. 8, p. 3088, doi. 10.1093/plcell/koac154

By:

Xinhang Zheng;
Anfei Fang;
Shanshan Qiu;
Guosheng Zhao;
Jiyang Wang;
Shanzhi Wang;
Junjun Wei;
Han Gao;
Jiyun Yang;
Baohui Mou;
Fuhao Cui;
Jie Zhang;
Jun Liu;
Wenxian Sun

Publication type:

Article

New Mechanism for Starch Dephosphorylation: Insight from the Structure of LIKE SEX FOUR2.

Published in:

Plant Cell, 2013, v. 25, n. 6, p. 1915, doi. 10.1105/tpc.113.250614

By:

Hofmann, Nancy R.

Publication type:

Article

Monitoring trafficking and expression of hemagglutinin-tagged transient receptor potential melastatin 4 channel in mammalian cells.

Published in:

Korean Journal of Physiology & Pharmacology, 2023, v. 27, n. 4, p. 417, doi. 10.4196/kjpp.2023.27.4.417

By:

Eun Mi Hwang;
Bo Hyun Lee;
Eun Hye Byun;
Soomin Lee;
Dawon Kang;
Dong Kun Lee;
Min Seok Song;
Seong-Geun Hong

Publication type:

Article

Hsa_circ_0129047 sponges miR-665 to attenuate lung adenocarcinoma progression by upregulating protein tyrosine phosphatase receptor type B.

Published in:

Korean Journal of Physiology & Pharmacology, 2023, v. 27, n. 2, p. 131, doi. 10.4196/kjpp.2023.27.2.131

By:

Xiaofan Xia;
Jinxiu Fan;
Zhongjie Fan

Publication type:

Article

Association of PTPN22 Haplotypes (−1123G>C/+1858C>T) with Rheumatoid Arthritis in Western Mexican Population.

Published in:

International Journal of Genomics, 2017, p. 1, doi. 10.1155/2017/8753498

By:

Ruiz-Noa, Yeniley;
Padilla-Gutiérrez, Jorge Ramón;
Hernández-Bello, Jorge;
Palafox-Sánchez, Claudia Azucena;
Valle, Yeminia;
Oregón-Romero, Edith;
Pereira-Suárez, Ana Laura;
Bernard-Medina, Ana Guilaisne;
Muñoz-Valle, José Francisco

Publication type:

Article

Antidiabetic Potential of Marine Brown Algae—a Mini Review.

Published in:

Journal of Diabetes Research, 2020, p. 1, doi. 10.1155/2020/1230218

By:

Gunathilaka, Thilina L.;
Samarakoon, Kalpa;
Ranasinghe, Pathmasiri;
Peiris, L. Dinithi C.

Publication type:

Article

Subunit contributions to phosphorylation-dependent modulation of bovine rod cyclic nucleotide-gated channels.

Published in:

Journal of Physiology, 2003, v. 552, n. 2, p. 345, doi. 10.1113/jphysiol.2003.047167

By:

Molokanova, Elena;
Krajewski, Jeffrey L.;
Satpaev, Daulet;
Luetje, Charles W.;
Kramer, Richard H.

Publication type:

Article

Analysis and identification of mRNAsi-related expression signatures via RNA sequencing in lung cancer.

Published in:

Oncology Letters, 2024, v. 28, n. 5, p. 1, doi. 10.3892/ol.2024.14682

By:

BO YAN;
YONG CHEN;
ZHOUYU WANG;
JING LI;
RUIRU WANG;
XUFENG PAN;
BOYI LI;
RONG LI

Publication type:

Article

Comprehensive transcriptomic profiling of liver cancer identifies that histone and PTEN are major regulators of SCU‑induced antitumor activity.

Published in:

Oncology Letters, 2024, v. 27, n. 3, p. N.PAG, doi. 10.3892/ol.2024.14227

By:

Ha, Sang Eun;
Paramanantham, Anjugam;
Kim, Hun Hwan;
Bhosale, Pritam Bhagwan;
Park, Min Yeong;
Abusaliya, Abuyaseer;
Heo, Jeong Doo;
Lee, Won Sup;
Kim, Gon Sup

Publication type:

Article

SHP2 is involved in the occurrence, development and prognosis of cancer.

Published in:

Oncology Letters, 2023, v. 26, n. 3, p. N.PAG, doi. 10.3892/ol.2023.13979

By:

Li, Shu;
Qu, Jialing;
Wang, Xiaotong;
Zou, Qin;
Li, Chunli

Publication type:

Article

Curcumin inhibits proliferation of hepatocellular carcinoma cells by blocking PTPN1 and PTPN11 expression.

Published in:

Oncology Letters, 2023, v. 26, n. 1, p. N.PAG, doi. 10.3892/ol.2023.13893

By:

Zhang, Jingru;
Liu, Yang;
Wang, Xiaojie;
Wang, Zhiyi;
Xing, Enjia;
Li, Jingmin;
Wang, Dong

Publication type:

Article