Works matching DE "PROTEIN-drug interactions"

Results: 83

Supporting precision medicine by data mining across multi-disciplines: an integrative approach for generating comprehensive linkages between single nucleotide variants (SNVs) and drug-binding sites.

Published in:

Bioinformatics, 2017, v. 33, n. 11, p. 1621, doi. 10.1093/bioinformatics/btx031

By:

Choudhury, Amrita Roy;
Tiejun Cheng;
Phan, Lon;
Bryant, Stephen H.;
Yanli Wang

Publication type:

Article

SPOT-ligand 2: improving structure-based virtual screening by binding-homology search on an expanded structural template library.

Published in:

Bioinformatics, 2017, v. 33, n. 8, p. 1238, doi. 10.1093/bioinformatics/btw829

By:

Litfin, Thomas;
Yaoqi Zhou;
Yuedong Yang

Publication type:

Article

Identification of drug-target interaction from interactome network with 'guilt-by-association' principle and topology features.

Published in:

Bioinformatics, 2016, v. 32, n. 7, p. 1057, doi. 10.1093/bioinformatics/btv695

By:

Zhan-Chao Li;
Meng-Hua Huang;
Wen-Qian Zhong;
Zhi-Qing Liu;
Yun Xie;
Zong Dai;
Xiao-Yong Zou

Publication type:

Article

Relating drug–protein interaction network with drug side effects.

Published in:

Bioinformatics, 2012, v. 28, n. 18, p. i522, doi. 10.1093/bioinformatics/bts383

By:

Mizutani, Sayaka;
Pauwels, Edouard;
Stoven, Véronique;
Goto, Susumu;
Yamanishi, Yoshihiro

Publication type:

Article

A New Algorithm for Weekly Phenprocoumon Dose Variation in a Southern Brazilian Population: Role for CYP2C9, CYP3A4/5 and VKORC1 Genes Polymorphisms.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 114, n. 4, p. 323, doi. 10.1111/bcpt.12172

By:

Botton, Mariana R.;
Viola, Patrícia P.;
Bandinelli, Eliane;
Leiria, Tiago L. L.;
Rohde, Luis E. P.;
Hutz, Mara H.

Publication type:

Article

Inferring Drug-Protein–Side Effect Relationships from Biomedical Text.

Published in:

Genes, 2019, v. 10, n. 2, p. 159, doi. 10.3390/genes10020159

By:

Song, Min;
Baek, Seung Han;
Heo, Go Eun;
Lee, Jeong-Hoon

Publication type:

Article

Exploration of interaction scoring criteria in the CANDO platform.

Published in:

BMC Research Notes, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13104-019-4356-3

By:

Falls, Zackary;
Mangione, William;
Schuler, James;
Samudrala, Ram

Publication type:

Article

A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity.

Published in:

PLoS Pathogens, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.ppat.1004064

By:

Qi, Hangfei;
Olson, C. Anders;
Wu, Nicholas C.;
Ke, Ruian;
Loverdo, Claude;
Chu, Virginia;
Truong, Shawna;
Remenyi, Roland;
Chen, Zugen;
Du, Yushen;
Su, Sheng-Yao;
Al-Mawsawi, Laith Q.;
Wu, Ting-Ting;
Chen, Shu-Hua;
Lin, Chung-Yen;
Zhong, Weidong;
Lloyd-Smith, James O.;
Sun, Ren

Publication type:

Article

The Surprising Importance of Peptide Bond Contacts in Drug-Protein Interactions.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 33, p. 7887, doi. 10.1002/chem.201701031

By:

Parrish, Robert M.;
Sitkoff, Doree F.;
Cheney, Daniel L.;
Sherrill, C. David

Publication type:

Article

Indirect study of non-covalent protein complexes by MALDI mass spectrometry: Origins, advantages, and applications of the 'intensity-fading' approach.

Published in:

Mass Spectrometry Reviews, 2016, v. 35, n. 5, p. 559, doi. 10.1002/mas.21480

By:

Downard, Kevin M.

Publication type:

Article

Antiretroviral unbound concentration during pregnancy: piece of interest in the puzzle?

Published in:

2017

By:

Metsu, D.;
Toutain, P. L.;
Chatelut, E.;
Delobel, P.;
Gandia, P.

Publication type:

journal article

Role of FK506 binding protein 5 (FKBP5) in osteoclast differentiation.

Published in:

Modern Rheumatology, 2013, v. 23, n. 6, p. 1133, doi. 10.3109/s10165-012-0809-4

By:

Kimura, Miho;
Nagai, Tatsuo;
Matsushita, Reiko;
Hashimoto, Atsushi;
Miyashita, Toshiyuki;
Hirohata, Shunsei

Publication type:

Article

Effect of CdTe QDs on the protein-drug interactions.

Published in:

Nanotoxicology, 2012, v. 6, n. 3, p. 304, doi. 10.3109/17435390.2011.579359

By:

Xiao, Jianbo;
Kai, Guoyin;
Chen, Xiaoqing

Publication type:

Article

Leveraging 3D chemical similarity, target and phenotypic data in the identification of drug-protein and drug-adverse effect associations.

Published in:

Journal of Cheminformatics, 2016, v. 8, p. 1, doi. 10.1186/s13321-016-0147-1

By:

Vilar, Santiago;
Hripcsak, George

Publication type:

Article

All-Purpose Containers? Lipid-Binding Protein – Drug Interactions.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132096

By:

Beringhelli, Tiziana;
Gianazza, Elisabetta;
Maggioni, Daniela;
Scanu, Sandra;
Parravicini, Chiara;
Sensi, Cristina;
Monaco, Hugo L.;
Eberini, Ivano

Publication type:

Article

Adverse Drug Reaction Prediction Using Scores Produced by Large-Scale Drug-Protein Target Docking on High-Performance Computing Machines.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106298

By:

LaBute, Montiago X.;
Zhang, Xiaohua;
Lenderman, Jason;
Bennion, Brian J.;
Wong, Sergio E.;
Lightstone, Felice C.

Publication type:

Article

Investigating the Dynamic Aspects of Drug-Protein Recognition through a Combination of MD and NMR Analyses: Implications for the Development of Protein-Protein Interaction Inhibitors.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097153

By:

Meli, Massimiliano;
Pagano, Katiuscia;
Ragona, Laura;
Colombo, Giorgio

Publication type:

Article

Depletion of FKBP51 in Female Mice Shapes HPA Axis Activity.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095796

By:

Hoeijmakers, Lianne;
Harbich, Daniela;
Schmid, Bianca;
Lucassen, Paul J.;
Wagner, Klaus V.;
Schmidt, Mathias V.;
Hartmann, Jakob

Publication type:

Article

Immobilised Histidine Tagged β2-Adrenoceptor Oriented by a Diazonium Salt Reaction and Its Application in Exploring Drug-Protein Interaction Using Ephedrine and Pseudoephedrine as Probes.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094955

By:

Li, Qian;
Bian, Liujiao;
Zhao, Xinfeng;
Gao, Xiaokang;
Zheng, Jianbin;
Li, Zijian;
Zhang, Youyi;
Jiang, Ru;
Zheng, Xiaohui

Publication type:

Article

A Target-Disease Network Model of Second-Generation BCR-ABL Inhibitor Action in Ph+ ALL.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077155

By:

Rix, Uwe;
Colinge, Jacques;
Blatt, Katharina;
Gridling, Manuela;
Remsing Rix, Lily L.;
Parapatics, Katja;
Cerny-Reiterer, Sabine;
Burkard, Thomas R.;
Jäger, Ulrich;
Melo, Junia V.;
Bennett, Keiryn L.;
Valent, Peter;
Superti-Furga, Giulio

Publication type:

Article

iGPCR-Drug: A Web Server for Predicting Interaction between GPCRs and Drugs in Cellular Networking.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072234

By:

Xiao, Xuan;
Min, Jian-Liang;
Wang, Pu;
Chou, Kuo-Chen

Publication type:

Article

A Semi-Supervised Method for Drug-Target Interaction Prediction with Consistency in Networks

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062975

By:

Chen, Hailin;
Zhang, Zuping

Publication type:

Article

Functional Impact of ABCB1 Variants on Interactions between P-Glycoprotein and Methadone.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059419

By:

Hung, Chin-Chuan;
Chiou, Mu-Han;
Teng, Yu-Ning;
Hsieh, Yow-Wen;
Huang, Chieh-Liang;
Lane, Hsien-Yuan

Publication type:

Article

Daunorubicin forms a specific complex with a secreted serine protease of Streptomyces peucetius.

Published in:

World Journal of Microbiology & Biotechnology, 2014, v. 30, n. 1, p. 253, doi. 10.1007/s11274-013-1442-x

By:

Dubey, Rashmi;
Kattusamy, Karuppasamy;
Dharmalingam, Kuppamuthu;
Prasad, Ranjan

Publication type:

Article

Structural Basis of Non-Steroidal Anti-Inflammatory Drug Diclofenac Binding to Human Serum Albumin.

Published in:

Chemical Biology & Drug Design, 2015, v. 86, n. 5, p. 1178, doi. 10.1111/cbdd.12583

By:

Zhang, Yao;
Lee, Philbert;
Liang, Shichu;
Zhou, Zuping;
Wu, Xiaoyang;
Yang, Feng;
Liang, Hong

Publication type:

Article

Some Anti-Inflammatory Agents Inhibit Esterase Activities of Human Carbonic Anhydrase Isoforms I and II: An In Vitro Study.

Published in:

Chemical Biology & Drug Design, 2015, v. 86, n. 4, p. 857, doi. 10.1111/cbdd.12561

By:

Alım, Zuhal;
Kılınç, Namık;
İşgör, Mehmet M.;
Şengül, Bülent;
Beydemir, Şükrü

Publication type:

Article

X-ray Crystallographic and Fluorometric Analysis of the Interactions of Rhein to Human Serum Albumin.

Published in:

Chemical Biology & Drug Design, 2014, v. 83, n. 2, p. 167, doi. 10.1111/cbdd.12208

By:

Li, Mei;
Lee, Philbert;
Zhang, Yao;
Ma, ZhiYuan;
Yang, Feng;
Zhou, ZuPing;
Wu, XiaoYang;
Liang, Hong

Publication type:

Article

Tanshinone IIA combined with adriamycin inhibited malignant biological behaviors of NSCLC A549 cell line in a synergistic way.

Published in:

BMC Cancer, 2016, v. 16, p. 1, doi. 10.1186/s12885-016-2921-x

By:

Jun Xie;
Jia-Hui Liu;
Heng Liu;
Xiao-Zhong Liao;
Yuling Chen;
Mei-Gui Lin;
Yue-Yu Gu;
Tao-Li Liu;
Dong-Mei Wang;
Hui Ge;
Sui-Lin Mo

Publication type:

Article

Using the drug-protein interactome to identify anti-ageing compounds for humans.

Published in:

PLoS Computational Biology, 2019, v. 15, n. 01, p. 1, doi. 10.1371/journal.pcbi.1006639

By:

Fuentealba, Matías;
Dönertaş, Handan Melike;
Williams, Rhianna;
Labbadia, Johnathan;
Thornton, Janet M.;
Partridge, Linda

Publication type:

Article

Diverse cutaneous side effects associated with BRAF inhibitor therapy: a clinicopathologic study.

Published in:: Current Medical Literature: Dermatology, 2012, v. 17, n. 3, p. 79
Publication type:: Article

Current limitations and future opportunities for prediction of DILI from in vitro.

Published in:

Archives of Toxicology, 2017, v. 91, n. 1, p. 131, doi. 10.1007/s00204-016-1874-9

By:

Funk, Christoph;
Roth, Adrian

Publication type:

Article

Molecular dynamics simulation studies of betulinic acid with human serum albumin.

Published in:

Journal of Molecular Modeling, 2012, v. 18, n. 6, p. 2589, doi. 10.1007/s00894-011-1287-x

By:

Malleda, Chandramouli;
Ahalawat, Navjeet;
Gokara, Mahesh;
Subramanyam, Rajagopal

Publication type:

Article

A Modified Amino Acid Network Model Contains Similar and Dissimilar Weight.

Published in:

Computational & Mathematical Methods in Medicine, 2013, p. 1, doi. 10.1155/2013/197892

By:

Xiong Jiao;
Lifeng Yang;
Meiwen An;
Weiyi Chen

Publication type:

Article

How does fatty acid influence anti-thyroid drugs binding and specificity toward protein human serum albumin? A blind docking simulation study.

Published in:

Journal of Chemical Sciences, 2014, v. 126, n. 6, p. 1929, doi. 10.1007/s12039-014-0718-5

By:

PAUL, BIJAN;
GUCHHAIT, NIKHIL

Publication type:

Article

FLEXc: protein flexibility prediction using context-based statistics, predicted structural features, and sequence information.

Published in:

2016

By:

Yaseen, Ashraf;
Nijim, Mais;
Williams, Brandon;
Lei Qian;
Min Li;
Jianxin Wang;
Yaohang Li

Publication type:

Abstract

Modeling the functional state of the reverse transcriptase of hepatitis B virus and its application to probing drug-protein interaction.

Published in:

BMC Bioinformatics, 2016, v. 17, p. 583, doi. 10.1186/s12859-016-1116-4

By:

Xiaojun Xu;
Hong Thai;
Kitrinos, Kathryn M.;
Guoliang Xia;
Gaggar, Anuj;
Paulson, Matthew;
Ganova-Raeva, Lilia;
Khudyakov, Yury;
Lara, James

Publication type:

Article

Development and Validation of a Free Carbamazepine Assay on an Automated Chemistry Analyzer.

Published in:

Journal of Applied Laboratory Medicine, 2020, v. 5, n. 2, p. 357, doi. 10.1093/jalm/jfz003

By:

Xiaochun Zhang;
Boyert, Nicole;
Mitro, Matthew;
Tang, Xiaoying;
Bowers, Kathleen;
McShane, Adam J.

Publication type:

Article

Kinetics of protein-ligand unbinding via smoothed potential molecular dynamics simulations.

Published in:

Scientific Reports, 2015, p. 11539, doi. 10.1038/srep11539

By:

Mollica, Luca;
Decherchi, Sergio;
Zia, Syeda Rehana;
Gaspari, Roberto;
Cavalli, Andrea;
Rocchia, Walter

Publication type:

Article

Comprehensive prediction of drug-protein interactions and side effects for the human proteome.

Published in:

Scientific Reports, 2015, p. 11090, doi. 10.1038/srep11090

By:

Zhou, Hongyi;
Gao, Mu;
Skolnick, Jeffrey

Publication type:

Article

Exploring the binding sites and binding mechanism for hydrotrope encapsulated griseofulvin drug on γ-tubulin protein.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190209

By:

Das, Shubhadip;
Paul, Sandip

Publication type:

Article

SELF-BLM: Prediction of drug-target interactions via self-training SVM.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171839

By:

Keum, Jongsoo;
Nam, Hojung

Publication type:

Article

The Relationship between Hydrophobicity and Drug-Protein Binding in Human Serum Albumin: A Quartz Crystal Microbalance Study.

Published in:

Biophysica, 2022, v. 2, n. 2, p. 113, doi. 10.3390/biophysica2020012

By:

Alhankawi, Ahmad R.;
Al-Husseini, Jacob K.;
Spindler, Archie;
Baker, Clark;
Shoniwa, Tonderai T.;
Ahmed, Mohammed;
Chiarelli, Peter A.;
Johal, Malkiat S.

Publication type:

Article

A multitechnique approach to probe the interaction of a therapeutic tyrosine kinase inhibitor nintedanib and bovine serum albumin.

Published in:

Preparative Biochemistry & Biotechnology, 2017, v. 47, n. 7, p. 655, doi. 10.1080/10826068.2016.1275014

By:

Abdelhameed, Ali Saber;
Nusrat, Saima;
Paliwal, Sanjhi;
Zaman, Masihuz;
Zaidi, Nida;
Khan, Rizwan Hasan

Publication type:

Article

Molecular encapsulation of Valganciclovir by β-cyclodextrin influences its binding to bovine serum albumin: a spectroscopic study.

Published in:

Physics & Chemistry of Liquids, 2019, v. 57, n. 1, p. 43, doi. 10.1080/00319104.2017.1408110

By:

Natesan, Sudha;
Enoch, Israel VMV

Publication type:

Article

Pharmaco-miR: linking microRNAs and drug effects.

Published in:

Briefings in Bioinformatics, 2014, v. 15, n. 4, p. 648, doi. 10.1093/bib/bbs082

By:

Rukov, Jakob Lewin;
Wilentzik, Roni;
Jaffe, Ishai;
Vinther, Jeppe;
Shomron, Noam

Publication type:

Article

An in silico approach to analyze HCV genotype-specific binding-site variation and its effect on drug–protein interaction.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77720-9

By:

Khalid, Ramsha;
Anwar, Muhammad Faraz;
Raees, Muhammad Aanish;
Naeem, Sadaf;
Abidi, Syed Hani;
Ali, Syed

Publication type:

Article

A model-based analysis of phenytoin and carbamazepine toxicity treatment using binding-competition during hemodialysis.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68333-3

By:

Maheshwari, Vaibhav;
Hoffman, Robert S.;
Thijssen, Stephan;
Tao, Xia;
Fuertinger, Doris H.;
Kotanko, Peter

Publication type:

Article

Incorporating chemical sub-structures and protein evolutionary information for inferring drug-target interactions.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62891-2

By:

Wang, Lei;
You, Zhu-Hong;
Li, Li-Ping;
Yan, Xin;
Zhang, Wei

Publication type:

Article

JAMI: a Java library for molecular interactions and data interoperability.

Published in:

BMC Bioinformatics, 2018, v. 19, p. 1, doi. 10.1186/s12859-018-2119-0

By:

Sivade (Dumousseau), M.;
Koch, M.;
Shrivastava, A.;
Alonso-López, D.;
De Las Rivas, J.;
del-Toro, N.;
Combe, C. W.;
Meldal, B. H. M.;
Heimbach, J.;
Rappsilber, J.;
Sullivan, J.;
Yehudi, Y.;
Orchard, S.

Publication type:

Article

Repositioning drugs by targeting network modules: a Parkinson's disease case study.

Published in:

BMC Bioinformatics, 2017, v. 18, p. 17, doi. 10.1186/s12859-017-1889-0

By:

Zongliang Yue;
Arora, Itika;
Zhang, Eric Y.;
Laufer, Vincent;
Bridges, S. Louis;
Chen, Jake Y.

Publication type:

Article