Works matching DE "PROTEIN kinase inhibitors"

Results: 2908

Cytomegalovirus viremia and hepatitis B reactivation in patient with RET fusion-positive non-small cell lung cancer treated with pralsetinib.

Published in:

Journal of Oncology Pharmacy Practice, 2025, v. 31, n. 4, p. 674, doi. 10.1177/10781552241304000

By:

Lehman, Alanna;
Perissinotti, Anthony;
Aitken, Sam

Publication type:

Article

Case report: Drug-induced vitiligo during treatment with BRAF/MEK inhibitors in a patient with metastatic conjunctival melanoma.

Published in:

Journal of Oncology Pharmacy Practice, 2025, v. 31, n. 4, p. 670, doi. 10.1177/10781552231189819

By:

Saray, Seray;
Hızlı, Pelin

Publication type:

Article

FDA Approves Taletrectinib for ROS1-Positive Non-Small Cell Lung Cancer.

Published in:: ONS Voice, 2025, p. N.PAG
Publication type:: Article

Perioperative Strategies in Resectable Non-Squamous Non-Small Cell Lung Cancer with EGFR Mutations and ALK Rearrangement.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1844, doi. 10.3390/cancers17111844

By:

Petrella, Francesco;
Cara, Andrea;
Cassina, Enrico Mario;
Degiovanni, Sara;
Libretti, Lidia;
Lo Torto, Sara;
Pirondini, Emanuele;
Raveglia, Federico;
Spinelli, Francesca;
Tuoro, Antonio;
Rizzo, Stefania

Publication type:

Article

Cardiovascular Safety Profile of BRAF and MEK Inhibitors in Melanoma: FAERS Data Through a Retrospective Disproportionality Analysis (2014–2023).

Published in:

Cancers, 2025, v. 17, n. 11, p. 1755, doi. 10.3390/cancers17111755

By:

Barbieri, Maria Antonietta;
Russo, Giulia;
Cicala, Giuseppe;
Zito, Concetta;
Spina, Edoardo;
Silvestris, Nicola;
Santarpia, Mariacarmela

Publication type:

Article

Treatment of Plexiform Neurofibromas : Current Perspectives on Surgery and Medical Treatment.

Published in:

Journal of Korean Neurosurgical Society, 2025, v. 68, n. 3, p. 252, doi. 10.3340/jkns.2025.0041

By:

Hwang, Jun Kyu;
Kim, Se Hoon;
Kim, Dong-Seok

Publication type:

Article

Response to a novel type II RAF inhibitor in diffuse leptomeningeal glioneuronal tumor with BRAF fusion.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf093

By:

Chun, Brie M;
Youngworth, Sandra;
Abtin, Vicki;
Stull, David;
Starkey, Jay;
Kummar, Shivaani

Publication type:

Article

Efficacy and safety of surufatinib in the treatment of thymic neuroendocrine tumors: a 102-case retrospective study.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyaf072

By:

Jia, Xuebing;
Sun, Zhichen;
Xu, Junyan;
Huang, Dan;
Chen, Fengzhen;
Chen, Jie;
Liang, Yun

Publication type:

Article

Efficacy of 2 different fibroblast growth factor receptor-inhibitors in a patient with extrahepatic cholangiocarcinoma harboring an FGFR2 mutation: a case report.

Published in:

Oncologist, 2025, v. 30, n. 5, p. 1, doi. 10.1093/oncolo/oyae294

By:

Galli-Vareia, Ilianna;
Szturz, Petr;
Voutsadakis, Ioannis A;
Villard, Nicolas;
Tsoumakidou, Georgia;
Fleury, Mapi;
Herrera, Gabriela;
Fasquelle, Francois;
Godat, Sebastien;
Digklia, Antonia

Publication type:

Article

Promising Drugs Targeting Specific Mechanisms of Deregulation in T Cell Lineage Acute Lymphoblastic Leukemia.

Published in:

Oncology & Therapy, 2025, v. 13, n. 2, p. 325, doi. 10.1007/s40487-025-00339-1

By:

Thomas, Xavier

Publication type:

Article

Recent Strategies to Attenuate Hepatocellular Carcinoma Recurrence After Liver Transplantation: A Narrative Review.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1650, doi. 10.3390/cancers17101650

By:

Endo, Yutaka;
Bekki, Yuki;
Hernandez-Alejandro, Roberto;
Tomiyama, Koji

Publication type:

Article

Cardiovascular Toxicity of Newer Chemotherapeutic Agents: The Heart of the Matter.

Published in:

Oncology (08909091), 2014, v. 28, n. 6, p. 493

By:

SHAIKH, AMIR Y.;
McGUINESS, MATTHEW E.;
SHIH, JEFFREY A.

Publication type:

Article

Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 696, doi. 10.1038/nsmb.2846

By:

Park, Suk-Youl;
Park, Jung-Eun;
Kim, Tae-Sung;
Kim, Ju Hee;
Kwak, Mi-Jeong;
Ku, Bonsu;
Tian, Lan;
Murugan, Ravichandran N;
Ahn, Mija;
Komiya, Shinobu;
Hojo, Hironobu;
Kim, Nam-Hyung;
Kim, Bo Yeon;
Bang, Jeong K;
Erikson, Raymond L;
Lee, Ki Won;
Kim, Seung Jun;
Oh, Byung-Ha;
Yang, Wei;
Lee, Kyung S

Publication type:

Article

Cost-effectiveness analysis of EGFR mutation testing in patients with non-small cell lung cancer (NSCLC) with gefitinib or carboplatin-paclitaxel.

Published in:

2016

By:

Arrieta, Oscar;
Anaya, Pablo;
Morales-Oyarvide, Vicente;
Ramírez-Tirado, Laura;
Polanco, Ana;
Ramírez-Tirado, Laura Alejandra;
Polanco, Ana C

Publication type:

journal article

Why do cancer cells become "addicted" to oncogenic epidermal growth factor receptor?

Published in:

2007

By:

Mellinghoff, Ingo

Publication type:

journal article

Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.

Published in:

2006

By:

Boyle, David L.;
Jones, Toni L.;
Hammaker, Deepa;
Svensson, Camille I.;
Rosengren, Sanna;
Albani, Salvatore;
Sorkin, Linda;
Firestein, Gary S.

Publication type:

journal article

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.

Published in:

2006

By:

Pikman, Yana;
Lee, Benjamin H.;
Mercher, Thomas;
McDowell, Elizabeth;
Ebert, Benjamin L.;
Gozo, Maricel;
Cuker, Adam;
Wernig, Gerlinde;
Moore, Sandra;
Galinsky, Ilene;
DeAngelo, Daniel J.;
Clark, Jennifer J.;
Lee, Stephanie J.;
Golub, Todd R.;
Wadleigh, Martha;
Gilliland, D. Gary;
Levine, Ross L.

Publication type:

journal article

MONALEESA-2 Trial—A Beacon of Hope.

Published in:

2025

By:

Tripathi, Mayank;
Vineet, Kumar

Publication type:

Letter

Commonly used fertility drugs, a diet supplement, and stress force AMPK-dependent block of stemness and development in cultured mammalian embryos.

Published in:

Journal of Assisted Reproduction & Genetics, 2016, v. 33, n. 8, p. 1027, doi. 10.1007/s10815-016-0735-z

By:

Bolnick, Alan;
Abdulhasan, Mohammed;
Kilburn, Brian;
Xie, Yufen;
Howard, Mindie;
Andresen, Paul;
Shamir, Alexandra;
Dai, Jing;
Puscheck, Elizabeth;
Rappolee, Daniel

Publication type:

Article

Personalized Care in the Prevention of Treatment-Related Cardiac Dysfunction in Female Cancer Survivors.

Published in:

Journal of Women's Health (15409996), 2019, v. 28, n. 10, p. 1384, doi. 10.1089/jwh.2018.6979

By:

Pituskin, Edith;
Perri, Melissa;
Cox-Kennett, Nanette;
Andrews, Elisha;
Dimitry, Rebecca;
McNeely, Margaret;
Paterson, Ian

Publication type:

Article

Simple Synthesis of a Heterocyclophane Exhibiting Anti‐c‐Met Activity by Acting as a Hatch Blocking Access to the Active Site**.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 5, p. 1648, doi. 10.1002/chem.202001382

By:

Takimoto, Tatsuya;
Sasaki, Hideaki;
Tsue, Hirohito;
Takahashi, Hiroki;
MacKerell, Alexander D.;
Nakamura, Ayumi;
Nakano, Katsuya;
Okazaki, Eori;
Betsuyaku, Tatsuki;
Tachibana, Ryosuke;
Hioki, Kazuhito;
Yoluk, Ozge;
Jo, Sunhwan

Publication type:

Article

Discovery of a Potent Allosteric Kinase Modulator by Combining Computational and Synthetic Methods.

Published in:

Angewandte Chemie, 2015, v. 127, n. 47, p. 14139, doi. 10.1002/ange.201506310

By:

Kroon, Edwin;
Schulze, Jörg O.;
Süß, Evelyn;
Camacho, Carlos J.;
Biondi, Ricardo M.;
Dömling, Alexander

Publication type:

Article

Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model.

Published in:

Journal of Headache & Pain, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s10194-019-1070-4

By:

Long, Ting;
He, Wei;
Pan, Qi;
Zhang, Shanshan;
Zhang, Dunke;
Qin, Guangcheng;
Chen, Lixue;
Zhou, Jiying

Publication type:

Article

Treatment-related adverse events in patients with advanced breast cancer receiving adjuvant AKT inhibitors: a meta-analysis of randomized controlled trials.

Published in:

European Journal of Clinical Pharmacology, 2024, v. 80, n. 9, p. 1373, doi. 10.1007/s00228-024-03713-6

By:

de Moraes, Francisco Cezar Aquino;
Sano, Vitor Kendi Tsuchiya;
Pereira, Caroline R. M.;
de Laia, Estella Aparecida;
Stecca, Carlos;
Magalhães, Maria Cristina Figueroa;
Burbano, Rommel Mario Rodríguez

Publication type:

Article

The effect of concomitant use of proton pump inhibitors with CDK 4/6 inhibitors on survival in metastatic breast cancer.

Published in:

European Journal of Clinical Pharmacology, 2023, v. 79, n. 2, p. 243, doi. 10.1007/s00228-022-03435-7

By:

Çağlayan, Dilek;
Koçak, Mehmet Zahid;
Geredeli, Çağlayan;
Tatlı, Ali Murat;
Göksu, Sema Sezgin;
Eryılmaz, Melek Karakurt;
Araz, Murat;
Artaç, Mehmet

Publication type:

Article

Effects of ABCB1 and ABCG2 polymorphisms on the pharmacokinetics of abemaciclib.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 8, p. 1239, doi. 10.1007/s00228-022-03331-0

By:

Maeda, Akimitsu;
Ando, Hitoshi;
Irie, Kei;
Hashimoto, Naoya;
Morishige, Jun-ichi;
Fukushima, Shoji;
Okada, Akira;
Ebi, Hiromichi;
Matsuzaki, Masahide;
Iwata, Hiroji;
Sawaki, Masataka

Publication type:

Article

Influences of ABC transporter and CYP3A4/5 genetic polymorphisms on the pharmacokinetics of lenvatinib in Chinese healthy subjects.

Published in:

European Journal of Clinical Pharmacology, 2020, v. 76, n. 8, p. 1125, doi. 10.1007/s00228-020-02879-z

By:

Li, Jiaming;
Wang, Xiaoqian;
Ning, Chen;
Wang, Zhaoyu;
Wang, Yao;
Zheng, Ming;
Zhang, Siliang;
Lu, Yang;
Zhang, Yongjie;
Li, Ning;
Chen, Xijing;
Zhao, Di

Publication type:

Article

Pharmacokinetics and pharmacogenetics of the MEK1/2 inhibitor, selumetinib, in Asian and Western healthy subjects: a pooled analysis.

Published in:

European Journal of Clinical Pharmacology, 2017, v. 73, n. 6, p. 717, doi. 10.1007/s00228-017-2217-3

By:

Dymond, Angela;
Elks, Cathy;
Martin, Paul;
Carlile, David;
Mariani, Gabriella;
Lovick, Susan;
Huang, Yifan;
Lorch, Ulrike;
Brown, Helen;
So, Karen

Publication type:

Article

Sunitinib treatment in a patient with metastatic renal cell carcinoma and bariatric surgery.

Published in:

2015

By:

van Kinschot, Caroline;
Erp, Nielka;
Feberwee, Tanja;
Dezentjé, Vincent

Publication type:

Letter

Oral and inhaled p38 MAPK inhibitors: effects on inhaled LPS challenge in healthy subjects.

Published in:

European Journal of Clinical Pharmacology, 2015, v. 71, n. 10, p. 1175, doi. 10.1007/s00228-015-1920-1

By:

Singh, Dave;
Siew, Leonard;
Christensen, Jared;
Plumb, Jonathan;
Clarke, Graham;
Greenaway, Steve;
Perros-Huguet, Christelle;
Clarke, Nick;
Kilty, Iain;
Tan, Lisa

Publication type:

Article

Multitargeted antiangiogenic tyrosine kinase inhibitors combined to chemotherapy in metastatic breast cancer: a systematic review and meta-analysis.

Published in:

European Journal of Clinical Pharmacology, 2014, v. 70, n. 5, p. 531, doi. 10.1007/s00228-014-1654-5

By:

Wang, Zexing;
Wang, Meiqi;
Yang, Fei;
Nie, Weiwei;
Chen, Fengxia;
Xu, Jing;
Guan, Xiaoxiang

Publication type:

Article

The effect of seasonal variation and secretion of sunitinib in sweat on the development of hand–foot syndrome.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 12, p. 2065, doi. 10.1007/s00228-013-1579-4

By:

Lankheet, Nienke A. G.;
Huitema, Alwin D. R.;
Mallo, Henk;
Adriaansz, Sandra;
Haanen, John B. A. G.;
Schellens, Jan H. M.;
Beijnen, Jos H.;
Blank, Christian U.

Publication type:

Article

Tofacitinib in Pediatric Psoriasis: An Open-Label Trial to Study Its Safety and Efficacy in Children.

Published in:

2020

By:

AlMutairi, Nawaf;
Nour, Tarek

Publication type:

journal article

Classification of Cushing’s syndrome PKAc mutants based upon their ability to bind PKI.

Published in:

Biochemical Journal, 2023, v. 480, n. 12, p. 875, doi. 10.1042/BCJ20230183

By:

Omar, Mitchell H.;
Kihiu, Maryanne;
Byrne, Dominic P.;
Lee, Kyung-Soon;
Lakey, Tyler M.;
Butcher, Erik;
Eyers, Patrick A.;
Scott, John D.

Publication type:

Article

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells.

Published in:

Biochemical Journal, 2022, v. 479, n. 19, p. 2131, doi. 10.1042/BCJ20220103

By:

Hunter, Jill E.;
Campbell, Amy E.;
Kerridge, Scott;
Fraser, Callum;
Hannaway, Nicola L.;
Luli, Saimir;
Ivanova, Iglika;
Brownridge, Philip J.;
Coxhead, Jonathan;
Taylor, Leigh;
Leary, Peter;
Hasoon, Megan S. R.;
Eyers, Claire E.;
Perkins, Neil D.

Publication type:

Article

Is Clinical Risk Score a Useful Predictive Marker of Early Recurrence Among Metastatic Breast Cancer Patients Treated with CDK4/6 Inhibitors?

Published in:

Eurasian Journal of Medical Investigation, 2024, v. 8, n. 2, p. 106, doi. 10.14744/ejmi.2024.52208

By:

Oven, Bala Basak;
Okten, Ilker Nihat;
Bilici, Ahmet;
Yasin, Ayse Irem;
Koca, Sinan;
Yuzugullu, Ezgi;
Celik, Serkan;
Kutlu, Yasin;
Seker, Mesut;
Simsek, Eda Tanrikulu;
Gumus, Mahmut

Publication type:

Article

Overcoming Hormone Resistance in Breast Cancer Cell Lines: The Impact of Combined Treatment with Sorafenib and Palbociclib on Cell Survival and Proliferation Pathways.

Published in:

Eurasian Journal of Medical Investigation, 2024, v. 8, n. 1, p. 13, doi. 10.14744/ejmi.2023.14963

By:

Almuradova, Elvina;
Kahraman, Erkan;
Goker, Erdem

Publication type:

Article

TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells.

Published in:

Advanced Biology, 2022, v. 6, n. 8, p. 1, doi. 10.1002/adbi.202200030

By:

Kim, Jaehee;
Oh, Juhyun;
Peterson, Hannah M.;
Carlson, Jonathan C.T.;
Pittet, Mikael J.;
Weissleder, Ralph

Publication type:

Article

Combination of Quercetin or/and siRNA-loaded DDAB-mPEG-PCL hybrid nanoparticles reverse resistance to Regorafenib in colon cancer cells.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03787-8

By:

Shahidi, Shabnam;
Rostamizadeh, Kobra;
Fathi, Mojtaba;
Nedaei, Keivan;
Ramazani, Ali

Publication type:

Article

Proangiogenesis effects of compound danshen dripping pills in zebrafish.

Published in:

BMC Complementary Medicine & Therapies, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12906-022-03589-y

By:

Hu, Yang-Xi;
You, Hong-Min;
Ren, Chang-Zhen;
Hu, Bo-Wen;
Zhang, Lu-Jun;
Zhang, Yan-Da;
He, Zhi-Qing;
Ding, Ru;
Guo, Zhi-Fu;
Liang, Chun

Publication type:

Article

Adaptive Darwinian off-target resistance mechanisms to selective RET inhibition in RET driven cancer.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00563-4

By:

Subbiah, Vivek;
Gouda, Mohamed A.;
Iorgulescu, J. Bryan;
Dadu, Ramona;
Patel, Keyur;
Sherman, Steven;
Cabanillas, Maria;
Hu, Mimi;
Castellanos, Luz E.;
Amini, Behrang;
Meric-Bernstam, Funda;
Shen, Tao;
Wu, Jie

Publication type:

Article

Refining Our Relationship to Cancer With Both Alleles.

Published in:

2025

By:

Rajagopal, Padma S.

Publication type:

Opinion

Health Care Resource Use for Modern First-Line Treatments in Metastatic Renal Cell Carcinoma.

Published in:

JAMA Network Open, 2024, v. 7, n. 7, p. e2422674, doi. 10.1001/jamanetworkopen.2024.22674

By:

Shah, Neil J.;
Shinde, Reshma;
Moore, Kristin J.;
Sainski-Nguyen, Amy;
Le, Lisa B.;
Cao, Feng;
Song, Rui;
Singhal, Puneet;
Motzer, Robert J.

Publication type:

Article

FDA Grants Accelerated Approval to Pirtobrutinib for Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma.

Published in:

ONS Voice, 2023, p. 1

By:

Lymphoma, Lymphocytic

Publication type:

Article

Oncology Drug Reference Sheet: Capmatinib.

Published in:

ONS Voice, 2023, p. 1

By:

Backler, Chelsea

Publication type:

Article

Current evidence on thyroid related adverse events in patients treated with protein tyrosine kinase inhibitors.

Published in:

Drug Metabolism Reviews, 2019, v. 51, n. 4, p. 562, doi. 10.1080/03602532.2019.1687512

By:

Gabora, Katalin;
Piciu, Andra;
Bădulescu, Iulian Claudiu;
Larg, Maria Iulia;
Stoian, Ioan-Adrian;
Piciu, Doina

Publication type:

Article

Methyl farnesoate regulatory mechanisms underlying photoperiod‐dependent sex determination in the freshwater crustacean Daphnia magna.

Published in:

Journal of Applied Toxicology, 2021, v. 41, n. 2, p. 216, doi. 10.1002/jat.4035

By:

Toyota, Kenji;
Sato, Tomomi;
Iguchi, Taisen;
Ohira, Tsuyoshi

Publication type:

Article

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.

Published in:

Science Immunology, 2016, v. 1, n. 2, p. 1, doi. 10.1126/sciimmunol.aag2045

By:

Kuriakose, Teneema;
Si Ming Man;
Malireddi, R. K. Subbarao;
Karki, Rajendra;
Kesavardhana, Sannula;
Place, David E.;
Neale, Geoffrey;
Vogel, Peter;
Kanneganti, Thirumala-Devi

Publication type:

Article

Single Center Experience of Sirolimus Therapy in Head and Neck Low-flow Vascular Malformations.

Published in:

Vascular & Endovascular Surgery, 2021, v. 55, n. 5, p. 482, doi. 10.1177/15385744211010378

By:

Pang, Calver;
Evans, Nicholas;
Jethwa, Poonam;
Papadopoulou, Anthie;
Khalifa, Mohamed;
Tsui, Janice;
Hamilton, George;
Lim, Chung Sim;
Brookes, Jocelyn

Publication type:

Article

Promoting Access to Innovative Anticancer Medicines: A Review of Drug Price and National Reimbursement Negotiation in China.

Published in:

Inquiry (00469580), 2023, p. 1, doi. 10.1177/00469580231170729

By:

Mingge, Xia;
Jingyu, Wen;
Qi, Liu;
Zhe, Zheng;
Qing, Ran

Publication type:

Article