Works matching DE "PROTEIN engineering"

Results: 2656

Engineered Prx-LCA2 fusion protein restores oxidative skin damage via enhanced intracellular peroxidase delivery.

Published in:

AMB Express, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13568-025-01906-5

By:

Liu, Di;
Zhan, Yafen;
Qu, Jiaqi;
Qiao, Hongping;
Li, Na;
Zhang, Yeli;
Wu, Xiaoying

Publication type:

Article

Optimised nanobody-based quenchbodies for enhanced protein detection.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08359-3

By:

Cater, Jordan H.;
El Salamouni, Nehad S.;
Mansour, Ghada H.;
Hutchinson, Sebastian;
Mc Guinness, Conall;
Mueller, Stefan H.;
Spinks, Richard R.;
Shanmugam, Nirukshan;
Pichard-Kostuch, Adeline;
Zahoransky, Viktor;
Ghodke, Harshad;
Ribezzi-Crivellari, Marco;
Yu, Haibo;
van Oijen, Antoine M.;
Griffiths, Andrew D.;
Spenkelink, Lisanne M.

Publication type:

Article

Enantiodivergent Radical Alkylation by Synergistic Lewis‐Acid‐Enzyme and Photoredox Catalysis.

Published in:

Angewandte Chemie, 2025, v. 137, n. 25, p. 1, doi. 10.1002/ange.202500338

By:

Zhang, Jiawei;
Zhang, Qiaoyu;
Ge, Ran;
Liu, Aokun;
Chen, Bin;
Zhang, Zihan;
Zhao, Beibei;
Yu, Jinhai;
Zhao, Yue;
Yu, Lu;
Cao, Mingfeng;
Wang, Binju;
Huang, Xiaoqiang

Publication type:

Article

ProBASS—a language model with sequence and structural features for predicting the effect of mutations on binding affinity Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 5, p. 1, doi. 10.1093/bioinformatics/btaf270

By:

Gurusinghe, Sagara N S;
Wu, Yibing;
DeGrado, William;
Shifman, Julia M

Publication type:

Article

Co-design protein sequence and structure in discrete space via generative flow Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 5, p. 1, doi. 10.1093/bioinformatics/btaf248

By:

Yang, Sen;
Ju, Lingli;
Cheng, Peng;
Zhou, JiangLin;
Cai, Yamin;
Feng, Dawei

Publication type:

Article

ProtNote: a multimodal method for protein–function annotation Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 5, p. 1, doi. 10.1093/bioinformatics/btaf170

By:

Char, Samir;
Corley, Nathaniel;
Alamdari, Sarah;
Yang, Kevin K;
Amini, Ava P

Publication type:

Article

Enhanced Thermal Stability/Activity of Geobacillus jurassicus Esterase by Rational Design and Application in the Synthesis of Cinnamyl Acetate.

Published in:

Applied Biochemistry & Biotechnology, 2025, v. 197, n. 6, p. 4109, doi. 10.1007/s12010-025-05223-2

By:

Li, Junze;
Song, Runfei;
Lin, Lin;
Li, Tao;
Yan, Yan;
Wei, Wei;
Wei, Dongzhi

Publication type:

Article

NanoBinder: a machine learning assisted nanobody binding prediction tool using Rosetta energy scores.

Published in:

Journal of Cheminformatics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13321-025-01040-1

By:

Shrestha, Palistha;
Talwar, Chandana S.;
Kandel, Jeevan;
Park, Kwang-Hyun;
Chong, Kil To;
Woo, Eui-Jeon;
Tayara, Hilal

Publication type:

Article

'Intelligent' proteins.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05770-1

By:

Tripathi, Timir;
Uversky, Vladimir N.;
Giuliani, Alessandro

Publication type:

Article

Prospects for Application of Bacillus amyloliquefaciens in Biocontrol, Metabolic Engineering, and Protein Expression.

Published in:

Applied Biochemistry & Microbiology, 2025, v. 61, n. 3, p. 443, doi. 10.1134/S0003683824606784

By:

Bataeva, Yu. V.;
Pokhilenko, V. D.;
Dunaitsev, I. A.;
Tekutov, A. R.;
Kalmantaev, T. A.

Publication type:

Article

Design and Analysis of a Highly Sensitive Terahertz Biosensor Using Graphene Metasurfaces and Surface Plasmon Resonance for Protein Detection with AI-Assisted Locally Weighted Linear Regression for Behavior Prediction.

Published in:

Plasmonics, 2025, v. 20, n. 6, p. 3619, doi. 10.1007/s11468-024-02563-3

By:

Dhandapani, Gokila;
Wekalao, Jacob;
Patel, Shobhit K.;
Al-zahrani, Fahad Ahmed

Publication type:

Article

An Enzymatic Platform for Aniline Synthesis Through Oxidative Amination.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202505252

By:

Zhao, Xiang;
Liu, Zhen

Publication type:

Article

Superfast Protein Desulfurization Triggered by Low‐Energy Visible Light.

Published in:

Angewandte Chemie, 2025, v. 137, n. 24, p. 1, doi. 10.1002/ange.202502884

By:

Han, Dongyang;
Deng, Xiangyu;
Cui, Yan;
Zhu, Xianglai;
Deng, Guiyu;
Liang, Lu‐Jun;
Chu, Guo‐Chao;
Liu, Lei

Publication type:

Article

Designing diverse and high-performance proteins with a large language model in the loop.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.pcbi.1013119

By:

Gomez-Uribe, Carlos A.;
Gado, Japheth;
Islamov, Meiirbek

Publication type:

Article

Applying computational protein design to therapeutic antibody discovery - current state and perspectives.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571371

By:

Bielska, Weronika;
Jaszczyszyn, Igor;
Dudzic, Pawel;
Janusz, Bartosz;
Chomicz, Dawid;
Wrobel, Sonia;
Greiff, Victor;
Feehan, Ryan;
Adolf-Bryfogle, Jared;
Krawczyk, Konrad

Publication type:

Article

Fein gesponnen: Was Hightech-Garne von der Natur lernen.

Published in:

IM + io, 2025, n. 2, p. 50

By:

Rosenberger, Isabel;
Milivojevic, Milena

Publication type:

Article

Development of a green Komagataella phaffii cell factory for sustainable production of plant-derived sesquiterpene (-)-a-bisabolol.

Published in:

Synthetic & Systems Biotechnology, 2025, v. 10, n. 1, p. 120, doi. 10.1016/j.synbio.2024.09.006

By:

Jintao Cheng;
Zhongji Pu;
Jiali Chen;
Dingfeng Chen;
Baoxian Li;
Zhengshun Wen;
Yuanxiang Jin;
Yanlai Yao;
Kan Shao;
Xiaosong Gu;
Guiling Yang

Publication type:

Article

AMPGen: an evolutionary information-reserved and diffusion-driven generative model for de novo design of antimicrobial peptides.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08282-7

By:

Jin, Shuwen;
Zeng, Zihan;
Xiong, Xiyan;
Huang, Baicheng;
Tang, Li;
Wang, Hongsheng;
Ma, Xiao;
Tang, Xiaochun;
Shao, Guoqing;
Huang, Xingxu;
Lin, Feng

Publication type:

Article

Selection of the optimal chelator for labeling of DARPin Ec1 with gallium-68 for PET imaging of EpCAM expression.

Published in:

EJNMMI Radiopharmacy & Chemistry, 2025, v. 10, n. 1, p. 1, doi. 10.1186/s41181-025-00347-6

By:

Vorobyeva, Anzhelika;
Din, Moeen-ud;
Schulga, Alexey;
Konovalova, Elena;
Abouzayed, Ayman;
Bragina, Olga;
Li, Ruonan;
Gräslund, Torbjörn;
Deyev, Sergey M.;
Oroujeni, Maryam

Publication type:

Article

Efficient Design of Affilin ® Protein Binders for HER3.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4683, doi. 10.3390/ijms26104683

By:

Diaz-Rovira, Anna M.;
Lotze, Jonathan;
Hoffmann, Gregor;
Pallara, Chiara;
Molina, Alexis;
Coburger, Ina;
Gloser-Bräunig, Manja;
Meysing, Maren;
Zwarg, Madlen;
Díaz, Lucía;
Guallar, Victor;
Bosse-Doenecke, Eva;
Roda, Sergi

Publication type:

Article

Reprogramming FGF1 from the natural growth factor to the engineered heparan sulphate biosensor.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02269-x

By:

Ciura, Krzysztof;
Sobota, Olimpia;
Chorążewska, Aleksandra;
Krowarsch, Daniel;
Porębska, Natalia;
Opaliński, Łukasz

Publication type:

Article

Reprogramming FGF1 from the natural growth factor to the engineered heparan sulphate biosensor.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02269-x

By:

Ciura, Krzysztof;
Sobota, Olimpia;
Chorążewska, Aleksandra;
Krowarsch, Daniel;
Porębska, Natalia;
Opaliński, Łukasz

Publication type:

Article

Control of repeat-protein curvature by computational protein design.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 2, p. 167, doi. 10.1038/nsmb.2938

By:

Park, Keunwan;
Shen, Betty W;
Parmeggiani, Fabio;
Huang, Po-Ssu;
Stoddard, Barry L;
Baker, David

Publication type:

Article

Protein Sequence Optimization—Theory, Practice, and Fundamental Impossibility.

Published in:

Soft Materials, 2004, v. 2, n. 1, p. 1, doi. 10.1081/SMTS-120030139

By:

Torda, AndrewE.

Publication type:

Article

IMPROVING STUDENT PREPAREDNESS FOR ENTERING THE WORKFORCE: A HANDS-ON EXPERIENCE IN PROJECT MANAGEMENT FOR A GRADUATE-LEVEL PROTEIN ENGINEERING CLASS.

Published in:

CEE: Chemical Engineering Education, 2020, v. 54, n. 4, p. 222, doi. 10.18260/2-1-370.660-119358

By:

PRAMOUNMAT, NUTTANIT;
RENNER, JULIE N.

Publication type:

Article

Enhancing the Activity of an Alcohol Dehydrogenase by Using "Aromatic Residue Scanning" at Potential Plasticity Sites.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 25, p. 1, doi. 10.1002/chem.202203530

By:

Ye, Wen‐Jie;
Xie, Jing‐Wen;
Liu, Yan;
Wang, Yi‐Lin;
Zhang, Yu‐Xin;
Yang, Xiao‐Ying;
Yang, Lin;
Wang, Hua‐Lei;
Wei, Dong‐Zhi

Publication type:

Article

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 67, p. 1, doi. 10.1002/chem.202201895

By:

Coleman, Tom;
Lee, Joel Z. H.;
Kirk, Alicia M.;
Doherty, Daniel Z.;
Podgorski, Matthew N.;
Pinidiya, Dilshi K.;
Bruning, John B.;
De Voss, James J.;
Krenske, Elizabeth H.;
Bell, Stephen G.

Publication type:

Article

Rational Enzyme Design without Structural Knowledge: A Sequence‐Based Approach for Efficient Generation of Transglycosylases.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 40, p. 10323, doi. 10.1002/chem.202100110

By:

Teze, David;
Zhao, Jiao;
Wiemann, Mathias;
Kazi, Zubaida G. A.;
Lupo, Rossana;
Zeuner, Birgitte;
Vuillemin, Marlène;
Rønne, Mette E.;
Carlström, Göran;
Duus, Jens Ø.;
Sanejouand, Yves‐Henri;
O'Donohue, Michael J.;
Nordberg Karlsson, Eva;
Fauré, Régis;
Stålbrand, Henrik;
Svensson, Birte

Publication type:

Article

An Evolutionary Strategy for Identification of Higher Order, Green Fluorescent Host–Guest Pairs Compatible with Living Systems.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 70, p. 16721, doi. 10.1002/chem.202002423

By:

Casey, Garrett R.;
Zhou, Xinqi;
Lesiak, Lauren;
Xu, Bi;
Fang, Yuan;
Becker, Donald F.;
Stains, Cliff I.

Publication type:

Article

Frontispiece: Tyrosine Conjugation Methods for Protein Labelling.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 63, p. 1, doi. 10.1002/chem.202086361

By:

Alvarez Dorta, Dimitri;
Deniaud, David;
Mével, Mathieu;
Gouin, Sébastien G.

Publication type:

Article

Enhancing Robustness of Sortase A by Loop Engineering and Backbone Cyclization.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 60, p. 13568, doi. 10.1002/chem.202002740

By:

Zou, Zhi;
Mate, Diana M.;
Nöth, Maximilian;
Jakob, Felix;
Schwaneberg, Ulrich

Publication type:

Article

Frontispiece: Biosynthetic Approaches towards the Design of Artificial Hydrogen‐Evolution Catalysts.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 55, p. 1, doi. 10.1002/chem.202085561

By:

Prasad, Pallavi;
Selvan, Dhanashree;
Chakraborty, Saumen

Publication type:

Article

Supramolecular Self‐Assembly of β<sup>3</sup>‐Peptides Mediated by Janus‐Type Recognition Units.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 53, p. 12145, doi. 10.1002/chem.202003107

By:

Kabata Glowacki, Selda;
Koszinowski, Konrad;
Hübner, Dennis;
Frauendorf, Holm;
Vana, Philipp;
Diederichsen, Ulf

Publication type:

Article

Frontispiece: Synthetic Strategies for Artificial Lipidation of Functional Proteins.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 21, p. 1, doi. 10.1002/chem.202082161

By:

Takahara, Mari;
Kamiya, Noriho

Publication type:

Article

Synthetic Strategies for Artificial Lipidation of Functional Proteins.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 21, p. 4645, doi. 10.1002/chem.201904568

By:

Takahara, Mari;
Kamiya, Noriho

Publication type:

Article

Cover Feature: Computer‐Assisted Recombination (CompassR) Teaches us How to Recombine Beneficial Substitutions from Directed Evolution Campaigns (Chem. Eur. J. 3/2020).

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 3, p. 566, doi. 10.1002/chem.201904578

By:

Cui, Haiyang;
Cao, Hao;
Cai, Haiying;
Jaeger, Karl‐Erich;
Davari, Mehdi D.;
Schwaneberg, Ulrich

Publication type:

Article

Accelerating the Association of the Most Stable Protein-Ligand Complex by More than Two Orders of Magnitude.

Published in:

Angewandte Chemie, 2016, v. 128, n. 32, p. 9496, doi. 10.1002/ange.201603652

By:

Giese, Christoph;
Eras, Jonathan;
Kern, Anne;
Schärer, Martin A.;
Capitani, Guido;
Glockshuber, Rudi

Publication type:

Article

Myoglobin-Catalyzed Olefination of Aldehydes.

Published in:

Angewandte Chemie, 2016, v. 128, n. 7, p. 2558, doi. 10.1002/ange.201508817

By:

Tyagi, Vikas;
Fasan, Rudi

Publication type:

Article

Impact of Strand Number on Parallel β-Sheet Stability.

Published in:

Angewandte Chemie, 2015, v. 127, n. 48, p. 14544, doi. 10.1002/ange.201506448

By:

Kung, Vanessa M.;
Cornilescu, Gabriel;
Gellman, Samuel H.

Publication type:

Article

Rational Structure-Based Design of Bright GFP-Based Complexes with Tunable Dimerization.

Published in:

Angewandte Chemie, 2015, v. 127, n. 47, p. 14158, doi. 10.1002/ange.201506686

By:

Eshaghi, Majid;
Sun, Guangyu;
Grüter, Andreas;
Lim, Chiew Ling;
Chee, Yuemin Celina;
Jung, Gregor;
Jauch, Ralf;
Wohland, Thorsten;
Chen, Swaine L.

Publication type:

Article

Modular Architecture of Protein Binding Units for Designing Properties of Cellulose Nanomaterials.

Published in:

Angewandte Chemie, 2015, v. 127, n. 41, p. 12193, doi. 10.1002/ange.201505980

By:

Malho, Jani ‐ Markus;
Arola, Suvi;
Laaksonen, Päivi;
Szilvay, Géza R.;
Ikkala, Olli;
Linder, Markus B.

Publication type:

Article

Creating Space for Large Acceptors: Rational Biocatalyst Design for Resveratrol Glycosylation in an Aqueous System.

Published in:

Angewandte Chemie, 2015, v. 127, n. 32, p. 9421, doi. 10.1002/ange.201503605

By:

Dirks-Hofmeister, Mareike E.;
Verhaeghe, Tom;
De Winter, Karel;
Desmet, Tom

Publication type:

Article

Enantioselective Enzymes by Computational Design and In Silico Screening.

Published in:

Angewandte Chemie, 2015, v. 127, n. 12, p. 3797, doi. 10.1002/ange.201411415

By:

Wijma, Hein J.;
Floor, Robert J.;
Bjelic, Sinisa;
Marrink, Siewert J.;
Baker, David;
Janssen, Dick B.

Publication type:

Article

Highly Diastereoselective and Enantioselective Olefin Cyclopropanation Using Engineered Myoglobin-Based Catalysts.

Published in:

Angewandte Chemie, 2015, v. 127, n. 6, p. 1764, doi. 10.1002/ange.201409928

By:

Bordeaux, Melanie;
Tyagi, Vikas;
Fasan, Rudi

Publication type:

Article

Reactive Oxygen Species-Responsive Protein Modification and Its Intracellular Delivery for Targeted Cancer Therapy.

Published in:

Angewandte Chemie, 2014, v. 126, n. 49, p. 13662, doi. 10.1002/ange.201407234

By:

Wang, Ming;
Sun, Shuo;
Neufeld, Caleb I.;
Perez ‐ Ramirez, Bernardo;
Xu, Qiaobing

Publication type:

Article

Selective Formation of Metastable Ferrihydrite in the Chiton Tooth.

Published in:

Angewandte Chemie, 2014, v. 126, n. 43, p. 11690, doi. 10.1002/ange.201406131

By:

Gordon, Lyle M.;
Román, Jessica K.;
Everly, R. Michael;
Cohen, Michael J.;
Wilker, Jonathan J.;
Joester, Derk

Publication type:

Article

A Smart Library of Epoxide Hydrolase Variants and the Top Hits for Synthesis of ( S)-β-Blocker Precursors.

Published in:

Angewandte Chemie, 2014, v. 126, n. 26, p. 6759, doi. 10.1002/ange.201402653

By:

Kong, Xu-Dong;
Ma, Qian;
Zhou, Jiahai;
Zeng, Bu-Bing;
Xu, Jian-He

Publication type:

Article

Control of the Conductance of Engineered Protein Nanopores through Concerted Loop Motions.

Published in:

Angewandte Chemie, 2014, v. 126, n. 23, p. 6007, doi. 10.1002/ange.201400400

By:

Zhuang, Tiandi;
Tamm, Lukas K.

Publication type:

Article

Combinatorially Designed Lipid-like Nanoparticles for Intracellular Delivery of Cytotoxic Protein for Cancer Therapy.

Published in:

Angewandte Chemie, 2014, v. 126, n. 11, p. 2937, doi. 10.1002/ange.201311245

By:

Wang, Ming;
Alberti, Kyle;
Sun, Shuo;
Arellano, Carlos Luis;
Xu, Qiaobing

Publication type:

Article

Proximity‐Enabled Protein Crosslinking through Genetically Encoding Haloalkane Unnatural Amino Acids.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2222, doi. 10.1002/ange.201308794

By:

Xiang, Zheng;
Lacey, Vanessa K.;
Ren, Haiyan;
Xu, Jing;
Burban, David J.;
Jennings, Patricia A.;
Wang, Lei

Publication type:

Article