Works matching DE "PROTEIN engineering"

Results: 2627

Revealing arginine-cysteine and glycine-cysteine NOS linkages by a systematic re-evaluation of protein structures.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01535-w

By:

Bazzi, Sophia;
Sayyad, Sharareh

Publication type:

Article

Semantical and geometrical protein encoding toward enhanced bioactivity and thermostability.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98033

By:

Yang Tan;
Bingxin Zhou;
Lirong Zheng;
Guisheng Fan;
Liang Hong

Publication type:

Article

Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104237

By:

Abramsson, Mia L.;
Corey, Robin A.;
Skerle, Jan L.;
Persson, Louise J.;
Anden, Olivia;
Oluwole, Abraham O.;
Howard, Rebecca J.;
Lindahl, Erik;
Robinson, Carol V.;
Strisovsky, Kvido;
Marklund, Erik G.;
Drew, David;
Stansfeld, Phillip J.;
Landreh, Michael

Publication type:

Article

Ene‐Reductases‐Catalyzed Non‐Natural Reactions.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 25, p. 1, doi. 10.1002/chem.202500539

By:

Chen, Jie;
Wu, Wenjing;
Peng, Yongzhen;
Fang, Zheng;
Hu, Yujing;
Guo, Kai

Publication type:

Article

The Promise of Protein Design: A Q&A with Nobel Laureate David Baker.

Published in:

GEN Biotechnology, 2025, v. 4, n. 1, p. 16, doi. 10.1089/genbio.2025.0004

By:

Baker, David;
Lin, Fay

Publication type:

Article

Cytokine Couture: Designer IL2 Molecules for the Treatment of Disease.

Published in:

ImmunoTargets & Therapy, 2025, v. 14, p. 403, doi. 10.2147/ITT.S500229

By:

Dashwood, Amy;
Ghodsinia, Arman Ali;
Dooley, James;
Liston, Adrian

Publication type:

Article

Shared-weight graph framework for comprehensive protein stability prediction across diverse mutation types.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf190

By:

Li, Gen;
Yao, Sijie;
Fan, Long

Publication type:

Article

ScFold: a GNN-based model for efficient inverse folding of short-chain proteins via spatial reduction.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf156

By:

Zhong, Jiancheng;
Zou, Zhiwei;
Qiu, Jie;
Wang, Shaokai

Publication type:

Article

|$\mathcal{S}$|able: bridging the gap in protein structure understanding with an empowering and versatile pre-training paradigm.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf120

By:

Li, Jiashan;
Chen, Xi;
Huang, He;
Zeng, Mingliang;
Yu, Jingcheng;
Gong, Xinqi;
Ye, Qiwei

Publication type:

Article

Design of diverse, functional mitochondrial targeting sequences across eukaryotic organisms using variational autoencoder.

Published in:

Nature Communications, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41467-025-59499-3

By:

Boob, Aashutosh Girish;
Tan, Shih-I;
Zaidi, Airah;
Singh, Nilmani;
Xue, Xueyi;
Zhou, Shuaizhen;
Martin, Teresa A.;
Chen, Li-Qing;
Zhao, Huimin

Publication type:

Article

IMPROVING STUDENT PREPAREDNESS FOR ENTERING THE WORKFORCE: A HANDS-ON EXPERIENCE IN PROJECT MANAGEMENT FOR A GRADUATE-LEVEL PROTEIN ENGINEERING CLASS.

Published in:

CEE: Chemical Engineering Education, 2020, v. 54, n. 4, p. 222, doi. 10.18260/2-1-370.660-119358

By:

PRAMOUNMAT, NUTTANIT;
RENNER, JULIE N.

Publication type:

Article

Deacetylation Ensures Timely Regulation of Flowering.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001646

By:

Coombs, Amy

Publication type:

Article

A Genetically Encoded Tag for Correlated Light and Electron Microscopy of Intact Cells, Tissues, and Organisms.

Published in:

PLoS Biology, 2011, v. 9, n. 4, p. 1, doi. 10.1371/journal.pbio.1001041

By:

Xiaokun Shu;
Lev-Ram, Varda;
Deerinck, Thomas J.;
Yingchuan Qi;
Ramko, Ericka B.;
Davidson, Michael W.;
Yishi Jin;
Ellisman, Mark H.;
Tsien, Roger Y.

Publication type:

Article

Global Conformational Dynamics of a Y-Family DNA Polymerase during Catalysis.

Published in:

PLoS Biology, 2009, v. 7, n. 10, p. 1, doi. 10.1371/journal.pbio.1000225

By:

Cuiling Xu;
Maxwell, Brian A.;
Brown, Jessica A.;
Likui Zhang;
Zucai Suo

Publication type:

Article

Evolutionary Influences on Proteins.

Published in:

PLoS Biology, 2007, v. 5, n. 2, p. 130, doi. 10.1371/journal.pbio.0050026

By:

Jones, Rachel

Publication type:

Article

Different Catalytic Mechanisms in Mammalian Selenocysteine- and Cysteine-Containing Methionine-R-Sulfoxide Reductases.

Published in:

PLoS Biology, 2005, v. 3, n. 11, p. 1, doi. 10.1371/journal.pbio.0030375

By:

Kim, Hwa-Young;
Gladyshev, Vadim N

Publication type:

Article

Testing and improving the performance of protein thermostability predictors for the engineering of cellulases.

Published in:

Journal of Bioinformatics & Computational Biology, 2023, v. 21, n. 2, p. 1, doi. 10.1142/S0219720023300010

By:

Dotsenko, Anna;
Denisenko, Jury;
Osipov, Dmitrii;
Rozhkova, Aleksandra;
Zorov, Ivan;
Sinitsyn, Arkady

Publication type:

Article

Hot spots localization in proteins by optimized short time Ramanujan Fourier transform.

Published in:

Journal of Bioinformatics & Computational Biology, 2021, v. 19, n. 2, p. N.PAG, doi. 10.1142/S0219720021500049

By:

Yadav, Yashpal;
Sharma, Sanjeev Narayan;
Shakya, Devendra Kumar;
Panchal, Abhishek

Publication type:

Article

The visualCMAT: A web-server to select and interpret correlated mutations/co-evolving residues in protein families.

Published in:

Journal of Bioinformatics & Computational Biology, 2018, v. 16, n. 2, p. -1, doi. 10.1142/S021972001840005X

By:

Suplatov, Dmitry;
Sharapova, Yana;
Timonina, Daria;
Kopylov, Kirill;
Švedas, Vytas

Publication type:

Article

A novel model-based on FCM-LM algorithm for prediction of protein folding rate.

Published in:

Journal of Bioinformatics & Computational Biology, 2017, v. 15, n. 4, p. -1, doi. 10.1142/S0219720017500123

By:

Liu, Longlong;
Ma, Mingjiao;
Cui, Jing

Publication type:

Article

STRUCTURE FLUCTUATIONS AND CONFORMATIONAL CHANGES IN PROTEIN BINDING.

Published in:

Journal of Bioinformatics & Computational Biology, 2012, v. 10, n. 2, p. 1241002-1, doi. 10.1142/S0219720012410028

By:

RUVINSKY, ANATOLY M.;
KIRYS, TATSIANA;
TUZIKOV, ALEXANDER V.;
VAKSER, ILYA A.

Publication type:

Article

OPTIMIZATION OF THERAPEUTIC PROTEINS TO DELETE T-CELL EPITOPES WHILE MAINTAINING BENEFICIAL RESIDUE INTERACTIONS.

Published in:

Journal of Bioinformatics & Computational Biology, 2011, v. 9, n. 2, p. 207, doi. 10.1142/S0219720011005471

By:

PARKER, ANDREW S.;
GRISWOLD, KARL E.;
BAILEY-KELLOGG, CHRIS

Publication type:

Article

Fragment‐Based Approach for Hierarchical Nanotube Assembly of Small Molecules in Aqueous Phase.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 20, p. 1, doi. 10.1002/chem.202404630

By:

Zia, Ayisha;
Yi, Meihui;
Liu, Zhiyu;
Wang, Fengbin;
Xu, Bing

Publication type:

Article

Active Site Engineering of a Glycerol Dehydrogenase Improves its Oxidative Activity and Scope Toward Glycerol Derivatives.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 6, p. 1, doi. 10.1002/chem.202403735

By:

Grajales‐Hernández, Daniel A.;
Roca, Maite;
Moliner, Vicent;
López‐Gallego, Fernando

Publication type:

Article

A Peptide Strategy for Inhibiting Different Protein Aggregation Pathways.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 52, p. 1, doi. 10.1002/chem.202400080

By:

Garfagnini, Tommaso;
Ferrari, Luca;
Koopman, Margreet B.;
Dekker, Françoise A.;
Halters, Sem;
Van Kappel, Eline;
Mayer, Guy;
Bressler, Shachar;
Maurice, Madelon M.;
Rüdiger, Stefan G. D.;
Friedler, Assaf

Publication type:

Article

Selective Oxidation of Vitamin D<sub>3</sub> Enhanced by Long‐Range Effects of a Substrate Channel Mutation in Cytochrome P450<sub>BM3</sub> (CYP102A1).

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 51, p. 1, doi. 10.1002/chem.202401487

By:

Chen, Wenyu;
Lynch, Jamie N. C.;
Bustamante, Claudia;
Zhang, Yuan;
Wong, Luet L.

Publication type:

Article

Design of Bright Chemogenetic Reporters Based on the Combined Engineering of Fluorogenic Molecular Rotors and of the HaloTag Protein.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 32, p. 1, doi. 10.1002/chem.202400641

By:

Coïs, Justine;
Bachollet, Sylvestre P. J. T.;
Sanchez, Louis;
Pietrancosta, Nicolas;
Vialou, Vincent;
Mallet, Jean‐Maurice;
Dumat, Blaise

Publication type:

Article

Cover Feature: Empowering Protein Engineering through Recombination of Beneficial Substitutions (Chem. Eur. J. 16/2024).

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 16, p. 1, doi. 10.1002/chem.202400753

By:

Wang, Xinyue;
Li, Anni;
Li, Xiujuan;
Cui, Haiyang

Publication type:

Article

Empowering Protein Engineering through Recombination of Beneficial Substitutions.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 16, p. 1, doi. 10.1002/chem.202303889

By:

Wang, Xinyue;
Li, Anni;
Li, Xiujuan;
Cui, Haiyang

Publication type:

Article

Synthesis of Trifluoromethylated Monoterpenes by an Engineered Cytochrome P450.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 10, p. 1, doi. 10.1002/chem.202302936

By:

Yuan, Feiyan;
Ding, Jing;
Sun, Yiyang;
Liang, Jianhua;
Luo, Yunzi;
Yu, Yang

Publication type:

Article

An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 8, p. 1, doi. 10.1002/chem.202303335

By:

Lee, Joel H. Z.;
Bruning, John B.;
Bell, Stephen G.

Publication type:

Article

Enhancing the Activity of an Alcohol Dehydrogenase by Using "Aromatic Residue Scanning" at Potential Plasticity Sites.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 25, p. 1, doi. 10.1002/chem.202203530

By:

Ye, Wen‐Jie;
Xie, Jing‐Wen;
Liu, Yan;
Wang, Yi‐Lin;
Zhang, Yu‐Xin;
Yang, Xiao‐Ying;
Yang, Lin;
Wang, Hua‐Lei;
Wei, Dong‐Zhi

Publication type:

Article

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 67, p. 1, doi. 10.1002/chem.202201895

By:

Coleman, Tom;
Lee, Joel Z. H.;
Kirk, Alicia M.;
Doherty, Daniel Z.;
Podgorski, Matthew N.;
Pinidiya, Dilshi K.;
Bruning, John B.;
De Voss, James J.;
Krenske, Elizabeth H.;
Bell, Stephen G.

Publication type:

Article

Proximity‐Enabled Protein Crosslinking through Genetically Encoding Haloalkane Unnatural Amino Acids.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2222, doi. 10.1002/ange.201308794

By:

Xiang, Zheng;
Lacey, Vanessa K.;
Ren, Haiyan;
Xu, Jing;
Burban, David J.;
Jennings, Patricia A.;
Wang, Lei

Publication type:

Article

Proximity-Enabled Protein Crosslinking through Genetically Encoding Haloalkane Unnatural Amino Acids.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2222, doi. 10.1002/ange.201308794

By:

Xiang, Zheng;
Lacey, Vanessa K.;
Ren, Haiyan;
Xu, Jing;
Burban, David J.;
Jennings, Patricia A.;
Wang, Lei

Publication type:

Article

An Atypical Naturally Split Intein Engineered for Highly Efficient Protein Labeling.

Published in:

Angewandte Chemie, 2014, v. 126, n. 5, p. 1330, doi. 10.1002/ange.201307969

By:

Thiel, Ilka V.;
Volkmann, Gerrit;
Pietrokovski, Shmuel;
Mootz, Henning D.

Publication type:

Article

An Antibody with a Variable-Region Coiled-Coil 'Knob' Domain.

Published in:

Angewandte Chemie, 2014, v. 126, n. 1, p. 136, doi. 10.1002/ange.201307939

By:

Zhang, Yong;
Goswami, Devrishi;
Wang, Danling;
Wang, Tsung ‐ Shing Andrew;
Sen, Shiladitya;
Magliery, Thomas J.;
Griffin, Patrick R.;
Wang, Feng;
Schultz, Peter G.

Publication type:

Article

Mn-porphyrins in a four-helix bundle participate in photo-induced electron transfer with a bacterial reaction center.

Published in:

Photosynthesis Research, 2024, v. 162, n. 2, p. 1, doi. 10.1007/s11120-023-01051-9

By:

Williams, J. C.;
Faillace, M. S.;
Gonzalez, E. J.;
Dominguez, R. E.;
Knappenberger, K.;
Heredia, D. A.;
Moore, T. A.;
Moore, A. L.;
Allen, J. P.

Publication type:

Article

Designing photosystem II: molecular engineering of photo-catalytic proteins.

Published in:

Photosynthesis Research, 2008, v. 98, n. 1-3, p. 687, doi. 10.1007/s11120-008-9355-5

By:

Brendon Conlan

Publication type:

Article

Influence of chemical shift tolerances on NMR structure calculations using ARIA protocols for assigning NOE data.

Published in:

Journal of Biomolecular NMR, 2005, v. 31, n. 1, p. 21, doi. 10.1007/s10858-004-5359-4

By:

Fossi, Michele;
Linge, Jens;
Labudde, Dirk;
Leitner, Dietmar;
Nilges, Michael;
Oschkinat, Hartmut

Publication type:

Article

Efficient identification of amino acid types for fast protein backbone assignments.

Published in:

Journal of Biomolecular NMR, 2001, v. 21, n. 3, p. 269, doi. 10.1023/A:1012920832184

By:

Ou, Horng D.;
Lai, Helen C.;
Serber, Zach;
Dötsch, Volker

Publication type:

Article

Amide proton temperature coefficients as hydrogen bond indicators in proteins.

Published in:

Journal of Biomolecular NMR, 2001, v. 21, n. 3, p. 249, doi. 10.1023/A:1012911329730

By:

Cierpicki, Tomasz;
Otlewski, Jacek

Publication type:

Article

Membrane-bound structure and alignment of the antimicrobial β-sheet peptide gramicidin S derived from angular and distance constraints by solid state 19F-NMR.

Published in:

Journal of Biomolecular NMR, 2001, v. 21, n. 3, p. 191, doi. 10.1023/A:1012946026231

By:

Salgado, Jesús;
Grage, Stephan L.;
Kondejewski, Leslie H.;
Hodges, Robert S.;
McElhaney, Ronald N.;
Ulrich, Anne S.

Publication type:

Article

Direct structure refinement of high molecular weight proteins against residual dipolar couplings and carbonyl chemical shift changes upon alignment: an application to maltose binding protein.

Published in:

Journal of Biomolecular NMR, 2001, v. 21, n. 1, p. 31, doi. 10.1023/A:1011933020122

By:

Choy, Wing-Yiu;
Tollinger, Martin;
Mueller, Geoffrey A.;
Kay, Lewis E.

Publication type:

Article

Production of phenylpyruvic acid by engineered l-amino acid deaminase from Proteus mirabilis.

Published in:

Biotechnology Letters, 2022, v. 44, n. 5/6, p. 635, doi. 10.1007/s10529-022-03245-y

By:

Liu, Jia;
Liu, Jianmin;
Yang, Bin;
Gao, Cong;
Song, Wei;
Hu, Guipeng;
Liu, Liming;
Wu, Jing

Publication type:

Article

Design of fusion protein for efficient preparation of cyanovirin-n and rapid enrichment of pseudorabies virus.

Published in:

Biotechnology Letters, 2021, v. 43, n. 8, p. 1575, doi. 10.1007/s10529-021-03141-x

By:

Wang, Bin;
Yang, Zhi;
Gao, Dan;
Wang, Fei;
Liu, Min;
Chen, Guanjun;
Ma, Lixin;
Yu, Xiaolan

Publication type:

Article

Switching the secondary and natural activity of Nitrilase from Acidovorax facilis 72 W for the efficient production of 2-picolinamide.

Published in:

Biotechnology Letters, 2021, v. 43, n. 8, p. 1617, doi. 10.1007/s10529-021-03137-7

By:

Wang, Liuzhu;
Jiang, Shuiqin;
Sun, Yangyang;
Yang, Zeyu;
Chen, Zhi;
Wang, Hualei;
Wei, Dongzhi

Publication type:

Article

Characterization and engineering of two new GH9 and GH48 cellulases from a Bacillus pumilus isolated from Lake Bogoria.

Published in:

Biotechnology Letters, 2021, v. 43, n. 3, p. 691, doi. 10.1007/s10529-020-03056-z

By:

Ogonda, Lydia A.;
Saumonneau, Amélie;
Dion, Michel;
Muge, Edward K.;
Wamalwa, Benson M.;
Mulaa, Francis J.;
Tellier, Charles

Publication type:

Article

Small design from big alignment: engineering proteins with multiple sequence alignment as the starting point.

Published in:

Biotechnology Letters, 2020, v. 42, n. 8, p. 1305, doi. 10.1007/s10529-020-02914-0

By:

Wang, Tianwen;
Liang, Chen;
Hou, Yajing;
Zheng, Mengyuan;
Xu, Hongju;
An, Yafei;
Xiao, Sa;
Liu, Lu;
Lian, Shuaibin

Publication type:

Article

New trends in aggregating tags for therapeutic protein purification.

Published in:

Biotechnology Letters, 2018, v. 40, n. 5, p. 745, doi. 10.1007/s10529-018-2543-2

By:

Yang, Xiaofeng;
Pistolozzi, Marco;
Lin, Zhanglin

Publication type:

Article