Works about PROTEIN drugs

Results: 537

H2GnnDTI: hierarchical heterogeneous graph neural networks for drug–target interaction prediction Open Access.

Published in:

Bioinformatics, 2025, v. 41, n. 4, p. 1, doi. 10.1093/bioinformatics/btaf117

By:

Jing, Yueying;
Zhang, Dongxue;
Li, Limin

Publication type:

Article

Strategies and challenges of cytosolic delivery of proteins.

Published in:

Journal of Drug Targeting, 2025, v. 33, n. 6, p. 837, doi. 10.1080/1061186X.2025.2458616

By:

Li, Yuanyuan;
Du, Baojie;
Yu, Lichao;
Luo, Hong;
Rong, Haibo;
Gao, Xiangdong;
Yin, Jun

Publication type:

Article

Investigation into the pharmacodynamics and pharmacokinetics of recombinant human interferon alfa-2b vaginal suppository following process optimization in chinese rhesus macaque.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98813-3

By:

Zhang, Xueyan;
Zhou, Baisong;
Gong, Yihan;
Liu, Yulin

Publication type:

Article

Relational similarity-based graph contrastive learning for DTI prediction.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 2, p. 1, doi. 10.1093/bib/bbaf122

By:

Bian, Jilong;
Lu, Hao;
Wei, Limin;
Li, Yang;
Wang, Guohua

Publication type:

Article

SS-DTI: A deep learning method integrating semantic and structural information for drug-target interaction prediction.

Published in:

Journal of Bioinformatics & Computational Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1142/S0219720025500027

By:

Chun, Yujie;
Li, Huaihu;
Wang, Shunfang

Publication type:

Article

PUTRACER: A NOVEL METHOD FOR IDENTIFICATION OF CONTINUOUS-DOMAINS IN MULTI-DOMAIN PROTEINS.

Published in:

Journal of Bioinformatics & Computational Biology, 2013, v. 11, n. 1, p. -1, doi. 10.1142/S021972001340012X

By:

ARAB, SEYED SHAHRIAR;
GHARAMALEKI, MOHAMMADBAGHER PARSA;
PASHANDI, ZAIDDODINE;
MOBASSERI, REZVAN

Publication type:

Article

Inorganic Drugs as a Tool for Protein Structure Solving and Studies on Conformational Changes.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 16, p. 1, doi. 10.1002/chem.202202937

By:

Tolbatov, Iogann;
Marrone, Alessandro;
Shepard, William;
Chiaverini, Lorenzo;
Kahaly, Mousumi Upadhyay;
La Mendola, Diego;
Marzo, Tiziano;
Ciccone, Lidia

Publication type:

Article

Specific Lipid Studies in Complex Membranes by Solid‐State NMR Spectroscopy.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 70, p. 1, doi. 10.1002/chem.202202472

By:

van Beekveld, Roy A. M.;
Derks, Maik G. N.;
Kumar, Raj;
Smid, Leanna;
Maass, Thorben;
Medeiros‐Silva, João;
Breukink, Eefjan;
Weingarth, Markus

Publication type:

Article

Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo.

Published in:

Angewandte Chemie, 2013, v. 125, n. 27, p. 7018, doi. 10.1002/ange.201302181

By:

Kim, Tae Hyung;
Swierczewska, Magdalena;
Oh, Yumin;
Kim, AeRyon;
Jo, Dong Gyu;
Park, Jae Hyung;
Byun, Youngro;
Sadegh-Nasseri, Scheherazade;
Pomper, Martin G.;
Lee, Kang Choon;
Lee, Seulki

Publication type:

Article

Synthesis, characterization, and evaluation of enzymatically degradable poly( N-isopropylacrylamide- co-acrylic acid) hydrogels for colon-specific drug delivery.

Published in:

Polymers for Advanced Technologies, 2008, v. 19, n. 11, p. 1536, doi. 10.1002/pat.1162

By:

Li, Shengfang;
Liu, Xianli

Publication type:

Article

First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centromere-associated protein E (CENP-E), in patients with refractory cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 3, p. 733, doi. 10.1007/s00280-011-1756-z

By:

Chung, Vincent;
Heath, Elisabeth;
Schelman, William;
Johnson, Brendan;
Kirby, Lyndon;
Lynch, Kerlin;
Botbyl, Jeffrey;
Lampkin, Thomas;
Holen, Kyle

Publication type:

Article

Preparation and evaluation of chitosan-calcium-gellan gum beads for controlled release of protein.

Published in:

European Food Research & Technology, 2013, v. 237, n. 4, p. 467, doi. 10.1007/s00217-013-2021-y

By:

Yang, Fei;
Xia, Shuqin;
Tan, Chen;
Zhang, Xiaoming

Publication type:

Article

Transport of asymmetric dimethylarginine (ADMA) by cationic amino acid transporter 2 (CAT2), organic cation transporter 2 (OCT2) and multidrug and toxin extrusion protein 1 (MATE1).

Published in:

Amino Acids, 2013, v. 45, n. 4, p. 989, doi. 10.1007/s00726-013-1556-3

By:

Strobel, Joachim;
Müller, Fabian;
Zolk, Oliver;
Endreß, Beate;
König, Jörg;
Fromm, Martin;
Maas, Renke

Publication type:

Article

δ2-Opioid Receptors as a Target in Designing New Cardioprotective Drugs: the Role of Protein Kinase C, AMPK, and Sarcolemmal KATP Channels.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 173, n. 1, p. 33, doi. 10.47056/0365-9615-2022-173-1-43-46

By:

Mukhomedzyanov, A. V.;
Popov, S. V.;
Maslov, L. N.

Publication type:

Article

Production of Recombinant Protein Self-Assembly Nanocontainers in a Prokaryotic System.

Published in:

Bulletin of Experimental Biology & Medicine, 2020, v. 169, n. 3, p. 383, doi. 10.1007/s10517-020-04892-9

By:

Ovchinnikova, L. A.;
Terekhov, S. S.;
Filimonova, I. N.;
Kudryaeva, A. A.;
Lomakin, Ya. A.

Publication type:

Article

Developing protein therapeutics.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 5, p. 583, doi. 10.1111/jphp.12921

By:

Mahler, Hanns‐Christian

Publication type:

Article

High‐throughput oxidation screen of antibody–drug conjugates by analytical protein A chromatography following IdeS digest.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 5, p. 625, doi. 10.1111/jphp.12873

By:

Buecheler, Jakob W.;
Winzer, Matthias;
Weber, Christian;
Gieseler, Henning

Publication type:

Article

Immunogenicity assessment during the development of protein therapeutics.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 5, p. 584, doi. 10.1111/jphp.12810

By:

Rosenberg, Amy S.;
Sauna, Zuben E.

Publication type:

Article

Challenges for the pharmaceutical technical development of protein coformulations.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 5, p. 666, doi. 10.1111/jphp.12731

By:

Mueller, Claudia;
Altenburger, Ulrike;
Mohl, Silke

Publication type:

Article

Effects of localized interactions and surface properties on stability of protein‐based therapeutics.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 5, p. 609, doi. 10.1111/jphp.12658

By:

Mills, Brittney J.;
Laurence Chadwick, Jennifer S.

Publication type:

Article

Low‐volume solubility assessment during high‐concentration protein formulation development.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 5, p. 636, doi. 10.1111/jphp.12621

By:

Hofmann, Melanie;
Winzer, Matthias;
Weber, Christian;
Gieseler, Henning

Publication type:

Article

Trypsin as a novel potential absorption enhancer for improving the transdermal delivery of macromolecules.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 8, p. 1005

By:

Akira Yamamoto

Publication type:

Article

Novel mucoadhesive nasal inserts based on chitosan/hyaluronate polyelectrolyte complexes for peptide and protein delivery.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 2, p. 151, doi. 10.1211/jpp.61.02.0003

By:

Barbara Luppi;
Federica Bigucci;
Laura Mercolini;
Alessandro Musenga;
Milena Sorrenti;
Laura Catenacci;
Vittorio Zecchi

Publication type:

Article

Current Status of Alginate in Drug Delivery.

Published in:

Advances in Pharmacological & Pharmaceutical Sciences, 2020, p. 1, doi. 10.1155/2020/8886095

By:

Hariyadi, Dewi Melani;
Islam, Nazrul

Publication type:

Article

Insight into the Binding Interaction Mechanism of the Ligand M1069 with Human Serum Albumin and A2A Adenosine Receptor—A Biophysical Approach.

Published in:

Polycyclic Aromatic Compounds, 2025, v. 45, n. 2, p. 177, doi. 10.1080/10406638.2024.2399536

By:

Ahamed Azees, Shajith;
Manoharan, Rupavarshini;
Alanthata Govindan, Navaneeth;
Leon, Bernet Shano;
Subramani, Karthikeyan

Publication type:

Article

Progress in the application of spider silk protein in medicine.

Published in:

Journal of Biomaterials Applications, 2021, v. 36, n. 5, p. 859, doi. 10.1177/08853282211003850

By:

Liu, Yi;
Huang, Wei;
Meng, Minsi;
Chen, Minhui;
Cao, Chengjian

Publication type:

Article

Synthesis of mesoporous sodium hyaluronate microspheres via electrostatic spray method.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2024, v. 33, n. 11, p. 985, doi. 10.5246/jcps.2024.11.071

By:

Wei Huang;
Jie Zhu;
Yingshu Feng;
Dan Yang;
Firempong, Caleb Kesse;
Yang Qu;
Haibing He;
Hongfei Liu

Publication type:

Article

Microspheres as pulmonary delivery systems - A review.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2021, v. 30, n. 7, p. 545, doi. 10.5246/jcps.2021.07.043

By:

Hariyadi, Dewi Melani;
Hendradi, Esti;
Pratama, Herlina Eka;
Rahmadi, Mahardian

Publication type:

Article

The group of Professor Tao Liu used biosynthesis strategies to achieve diverse modifications of protein drugs.

Published in:: Journal of Chinese Pharmaceutical Sciences, 2021, v. 30, n. 2, p. 181
Publication type:: Article

ZeroBind: a protein-specific zero-shot predictor with subgraph matching for drug-target interactions.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43597-1

By:

Wang, Yuxuan;
Xia, Ying;
Yan, Junchi;
Yuan, Ye;
Shen, Hong-Bin;
Pan, Xiaoyong

Publication type:

Article

Rectifying disorder of extracellular matrix to suppress urethral stricture by protein nanofilm-controlled drug delivery from urinary catheter.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38282-2

By:

Tian, Juanhua;
Fu, Delai;
Liu, Yongchun;
Guan, Yibing;
Miao, Shuting;
Xue, Yuquan;
Chen, Ke;
Huang, Shanlong;
Zhang, Yanfeng;
Xue, Li;
Chong, Tie;
Yang, Peng

Publication type:

Article

In vitro and in vivo evaluation of microneedles coated with electrosprayed micro/nanoparticles for medical skin treatments.

Published in:

Journal of Microencapsulation, 2020, v. 37, n. 7, p. 517, doi. 10.1080/02652048.2020.1809725

By:

Tort, Serdar;
Mutlu Agardan, Necibe Basaran;
Han, Daewoo;
Steckl, Andrew J.

Publication type:

Article

Optimization of novel pentablock copolymer based composite formulation for sustained delivery of peptide/protein in the treatment of ocular diseases.

Published in:

Journal of Microencapsulation, 2016, v. 33, n. 2, p. 103, doi. 10.3109/02652048.2015.1134685

By:

Patel, Sulabh P.;
Vaishya, Ravi;
Patel, Ashaben;
Agrahari, Vibhuti;
Pal, Dhananjay;
Mitra, Ashim k.

Publication type:

Article

Poly(D,L-lactide- co -glycolide) protein-loaded nanoparticles prepared by the double emulsion method—processing and formulation issues for enhanced entrapment efficiency.

Published in:

Journal of Microencapsulation, 2005, v. 22, n. 2, p. 205, doi. 10.1080/02652040400026442

By:

Bilati, U.;
Allémann, E.;
Doelker, E.

Publication type:

Article

KNIME workflow for retrieving causal drug and protein interactions, building networks, and performing topological enrichment analysis demonstrated by a DILI case study.

Published in:

Journal of Cheminformatics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13321-022-00615-6

By:

Füzi, Barbara;
Malik-Sheriff, Rahuman S.;
Manners, Emma J.;
Hermjakob, Henning;
Ecker, Gerhard F.

Publication type:

Article

Exploring Enzyme Encapsulation Efficiency in MOFs Using Eco‐Friendly Approaches.

Published in:

ChemSusChem, 2025, v. 18, n. 3, p. 1, doi. 10.1002/cssc.202401568

By:

Hieu Vo, Trung;
Lin, Shang‐Wei;
Lin, Miao‐Chun;
Kuan, Pu‐Yun;
Chen, Jing‐Hui;
Huang, Hsin‐Kai;
Liu, Wen‐Tzu;
Xu, Hui;
Li, Ao;
Hsu, Yu‐An;
Wan, Lei;
Khanh Lam, Phuc;
Chou, Lien‐Yang;
Yang, Hsiao‐Ching;
Shieh, Fa‐Kuen

Publication type:

Article

Prediction of hot spots towards drug discovery by protein sequence embedding with 1D convolutional neural network.

Published in:

PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0290899

By:

Zhang, Youzhi;
Yao, Sijie;
Chen, Peng

Publication type:

Article

Germline VH/VL pairing in antibodies.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 523, doi. 10.1093/protein/gzs043

By:

Jayaram, Narayan;
Bhowmick, Pallab;
Martin, Andrew C.R.

Publication type:

Article

Computer-aided antibody design.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 507, doi. 10.1093/protein/gzs024

By:

Kuroda, Daisuke;
Shirai, Hiroki;
Jacobson, Matthew P.;
Nakamura, Haruki

Publication type:

Article

Improved drug-like properties of therapeutic proteins by directed evolution.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 631, doi. 10.1093/protein/gzs054

By:

Buchanan, Andrew;
Ferraro, Franco;
Rust, Steven;
Sridharan, Sudharsan;
Franks, Ruth;
Dean, Greg;
McCourt, Matthew;
Jermutus, Lutz;
Minter, Ralph

Publication type:

Article

Designed hydrophilic and charge mutations of the fibronectin domain: towards tailored protein biodistribution.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 639, doi. 10.1093/protein/gzs036

By:

Hackel, Benjamin J.;
Sathirachinda, Ataya;
Gambhir, Sanjiv S.

Publication type:

Article

Design and analysis of immune-evading enzymes for ADEPT therapy.

Published in:

PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 613, doi. 10.1093/protein/gzs044

By:

Osipovitch, Daniel C.;
Parker, Andrew S.;
Makokha, Christabell D.;
Desrosiers, Joseph;
Kett, Warren C.;
Moise, Leonard;
Bailey-Kellogg, Chris;
Griswold, Karl E.

Publication type:

Article

An evaluation tool for FKBP12-dependent and -independent mTOR inhibitors using a combination of FKBP-mTOR fusion protein, DSC and NMR.

Published in:

PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 11, p. 811, doi. 10.1093/protein/gzr045

By:

Sekiguchi, Mitsuhiro;
Kobashigawa, Yoshihiro;
Kawasaki, Masashi;
Yokochi, Masashi;
Kiso, Tetsuo;
Suzumura, Ken-ichi;
Mori, Keitaro;
Teramura, Toshio;
Inagaki, Fuyuhiko

Publication type:

Article

Humanization strategies for an anti-idiotypic antibody mimicking HIV-1 gp41.

Published in:

PEDS: Protein Engineering, Design & Selection, 2010, v. 23, n. 12, p. 947, doi. 10.1093/protein/gzq092

By:

Mader, A.;
Kunert, R.

Publication type:

Article

Microbial factories for recombinant pharmaceuticals.

Published in:

Microbial Cell Factories, 2009, v. 8, p. 1, doi. 10.1186/1475-2859-8-17

By:

Ferrer-Miralles, Neus;
Domingo-Espín, Joan;
Corchero, José Luis;
Vázquez, Esther;
Villaverde, Antonio

Publication type:

Article

Reduced middle ear infection with non-typeable Haemophilus influenzae, but not Streptococcus pneumoniae, after transition to 10-valent pneumococcal non-typeable H. influenzae protein D conjugate vaccine.

Published in:

2015

By:

Leach, Amanda Jane;
Wigger, Christine;
Hare, Kim;
Hampton, Vanya;
Beissbarth, Jemima;
Andrews, Ross;
Chatfield, Mark;
Smith-Vaughan, Heidi;
Morris, Peter Stanley

Publication type:

journal article

From byte to bench to bedside: molecular dynamics simulations and drug discovery.

Published in:

BMC Biology, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12915-023-01791-z

By:

Ahmed, Mayar;
Maldonado, Alex M.;
Durrant, Jacob D.

Publication type:

Article

Drug-target interaction prediction with tree-ensemble learning and output space reconstruction.

Published in:

BMC Bioinformatics, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12859-020-3379-z

By:

Pliakos, Konstantinos;
Vens, Celine

Publication type:

Article

Predicting drug-target interactions from drug structure and protein sequence using novel convolutional neural networks.

Published in:

BMC Bioinformatics, 2019, v. 20, p. 1, doi. 10.1186/s12859-019-3263-x

By:

Hu, ShanShan;
Zhang, Chenglin;
Chen, Peng;
Gu, Pengying;
Zhang, Jun;
Wang, Bing

Publication type:

Article

Metabolomics paves the way for improved drug target identification.

Published in:

Molecular Systems Biology, 2022, v. 18, n. 2, p. 1, doi. 10.15252/msb.202210914

By:

Garana, Belinda B;
Graham, Nicholas A

Publication type:

Article