Works matching DE "PROTEIN arginine methyltransferases"

Results: 448

Arginine methylation patterns in LUAD: defining prognostic subtypes and relevance to immunotherapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02549-5

By:

Shen, Qianyun;
Yang, Yijie;
Guan, Maoying;
Li, Hegen

Publication type:

Article

PRMT5 在妇科恶性肿瘤中的研究进展.

Published in:

Journal of International Reproductive Health/Family Planning, 2025, v. 44, n. 2, p. 171, doi. 10.12280/gjszjk.20240518

By:

宋萌萌;
陈芳;
包香香;
田馨莉

Publication type:

Article

Protein Arginine Methyltransferases from Regulatory Function to Clinical Implication in Central Nervous System.

Published in:

Cellular & Molecular Neurobiology, 2025, v. 45, n. 1, p. 1, doi. 10.1007/s10571-025-01546-0

By:

Xie, Bin;
Yu, Jing;
Chen, Chao;
Shen, Ting

Publication type:

Article

Prmt1-mediated methylation regulates Ncoa4 stability to transactivate Adamts genes and promote bone extracellular matrix degradation in chronic hematogenous osteomyelitis.

Published in:

Biology Direct, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13062-025-00652-9

By:

Chen, Xun;
Duan, Ning;
Zhang, Wentao;
Song, Tao;
Cong, Fei

Publication type:

Article

Retraction: Lead induces the upregulation of protein arginine methyltransferase 5 possibly by its promoter demethylation.

Published in:: Biochemical Journal, 2025, v. 482, n. 7, p. 367, doi. 10.1042/BCJ20180009_RET
Publication type:: Article

The effects of novokinin, an AT2 agonist, on blood pressure, vascular responses, and levels of ADMA, NADPH oxidase, and Rho kinase in hypertension induced by NOS inhibition and salt.

Published in:

Turkish Journal of Medical Sciences, 2016, v. 46, n. 4, p. 1249, doi. 10.3906/sag-1502-18

By:

MUTLU, Emre;
İLHAN, Selçuk;
ONAT, Elif;
KARA, Murat;
ŞAHNA, Engin

Publication type:

Article

Targeting CARM1 in ovarian cancer with EZH2 and PARP inhibitors.

Published in:

Molecular & Cellular Oncology, 2020, v. 7, n. 4, p. 1, doi. 10.1080/23723556.2020.1760675

By:

Karakashev, Sergey;
Zhang, Rugang

Publication type:

Article

Dual role of PRMT1-dependent arginine methylation in cellular responses to genotoxic stress.

Published in:

Molecular & Cellular Oncology, 2020, v. 7, n. 4, p. 1, doi. 10.1080/23723556.2020.1743808

By:

Giambruno, Roberto;
Bonaldi, Tiziana

Publication type:

Article

PRMT5 participates in B cell overactivation in patients with primary Sjogren's syndrome (pSS) through RSAD2‐mediated NF‐κB signaling.

Published in:

Immunity, Inflammation & Disease, 2023, v. 11, n. 12, p. 1, doi. 10.1002/iid3.1102

By:

Zhu, Hong;
Zheng, Jian;
Zhou, Yan;
Wu, Tong;
Zhu, Tiantian

Publication type:

Article

The interplay between H3K36 methylation and DNA methylation in cancer.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 8, p. 545, doi. 10.20892/j.issn.2095-3941.2023.0234

By:

Jiameng Dan;
Zeling Du;
Jinghong Zhang;
Taiping Chen

Publication type:

Article

PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo.

Published in:

Scientific Reports, 2024, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-48652-x

By:

Brown, Elizabeth J.;
Balaguer-Lluna, Leire;
Cribbs, Adam P.;
Philpott, Martin;
Campo, Leticia;
Browne, Molly;
Wong, Jong Fu;
Oppermann, Udo;
Carcaboso, Ángel M.;
Bullock, Alex N.;
Farnie, Gillian

Publication type:

Article

Autophagy dictates sensitivity to PRMT5 inhibitor in breast cancer.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-37706-9

By:

Brobbey, Charles;
Yin, Shasha;
Liu, Liu;
Ball, Lauren E.;
Howe, Philip H.;
Delaney, Joe R.;
Gan, Wenjian

Publication type:

Article

PRMT1 methylates the single Argonaute of Toxoplasma gondii and is important for the recruitment of Tudor nuclease for target RNA cleavage by antisense guide RNA.

Published in:

Cellular Microbiology, 2012, v. 14, n. 6, p. 882, doi. 10.1111/j.1462-5822.2012.01763.x

By:

Musiyenko, Alla;
Majumdar, Tanmay;
Andrews, Joel;
Adams, Brian;
Barik, Sailen

Publication type:

Article

Nuclear loss of protein arginine N-methyltransferase 2 in breast carcinoma is associated with tumor grade and overexpression of cyclin D1 protein.

Published in:

Oncogene, 2014, v. 33, n. 48, p. 5546, doi. 10.1038/onc.2013.500

By:

Zhong, J;
Cao, R-X;
Liu, J-H;
Liu, Y-B;
Wang, J;
Liu, L-P;
Chen, Y-J;
Yang, J;
Zhang, Q-H;
Wu, Y;
Ding, W-J;
Hong, T;
Xiao, X-H;
Zu, X-Y;
Wen, G-B

Publication type:

Article

Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47107-9

By:

Shen, Lei;
Ma, Xiaokuang;
Wang, Yuanyuan;
Wang, Zhihao;
Zhang, Yi;
Pham, Hoang Quoc Hai;
Tao, Xiaoqun;
Cui, Yuehua;
Wei, Jing;
Lin, Dimitri;
Abeywanada, Tharindumala;
Hardikar, Swanand;
Halabelian, Levon;
Smith, Noah;
Chen, Taiping;
Barsyte-Lovejoy, Dalia;
Qiu, Shenfeng;
Xing, Yi;
Yang, Yanzhong

Publication type:

Article

Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46711-z

By:

Katanasaka, Yasufumi;
Yabe, Harumi;
Murata, Noriyuki;
Sobukawa, Minori;
Sugiyama, Yuga;
Sato, Hikaru;
Honda, Hiroki;
Sunagawa, Yoichi;
Funamoto, Masafumi;
Shimizu, Satoshi;
Shimizu, Kana;
Hamabe-Horiike, Toshihide;
Hawke, Philip;
Komiyama, Maki;
Mori, Kiyoshi;
Hasegawa, Koji;
Morimoto, Tatsuya

Publication type:

Article

PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46495-2

By:

Lin, Chang-Ching;
Chang, Tsung-Cheng;
Wang, Yunguan;
Guo, Lei;
Gao, Yunpeng;
Bikorimana, Emmanuel;
Lemoff, Andrew;
Fang, Yisheng V.;
Zhang, He;
Zhang, Yanfeng;
Ye, Dan;
Soria-Bretones, Isabel;
Servetto, Alberto;
Lee, Kyung-min;
Luo, Xuemei;
Otto, Joseph J.;
Akamatsu, Hiroaki;
Napolitano, Fabiana;
Mani, Ram;
Cescon, David W.

Publication type:

Article

A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40798-6

By:

Antal, Corina E.;
Oh, Tae Gyu;
Aigner, Stefan;
Luo, En-Ching;
Yee, Brian A.;
Campos, Tania;
Tiriac, Hervé;
Rothamel, Katherine L.;
Cheng, Zhang;
Jiao, Henry;
Wang, Allen;
Hah, Nasun;
Lenkiewicz, Elizabeth;
Lumibao, Jan C.;
Truitt, Morgan L.;
Estepa, Gabriela;
Banayo, Ester;
Bashi, Senada;
Esparza, Edgar;
Munoz, Ruben M.

Publication type:

Article

PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38443-3

By:

Liu, Jing;
Bu, Xia;
Chu, Chen;
Dai, Xiaoming;
Asara, John M.;
Sicinski, Piotr;
Freeman, Gordon J.;
Wei, Wenyi

Publication type:

Article

ZNF468-mediated epigenetic upregulation of VEGF-C facilitates lymphangiogenesis and lymphatic metastasis in ESCC via PI3K/Akt and ERK1/2 signaling pathways.

Published in:

Cellular Oncology (2211-3428), 2024, v. 47, n. 5, p. 1927, doi. 10.1007/s13402-024-00976-0

By:

Zhu, Jinrong;
Qiu, Xiangyu;
Jin, Xin;
Nie, Xiaoya;
Ou, Shengming;
Wu, Geyan;
Shen, Jianfei;
Zhang, Rongxin

Publication type:

Article

The emerging role of CARM1 in cancer.

Published in:

Cellular Oncology (2211-3428), 2024, v. 47, n. 5, p. 1503, doi. 10.1007/s13402-024-00943-9

By:

Xie, Zizhuo;
Tian, Yuan;
Guo, Xiaohan;
Xie, Na

Publication type:

Article

Protein arginine methyltransferase 5: a potential cancer therapeutic target.

Published in:

Cellular Oncology (2211-3428), 2021, v. 44, n. 1, p. 33, doi. 10.1007/s13402-020-00577-7

By:

Yuan, Yuanyang;
Nie, Hong

Publication type:

Article

PRMT1 promotes pancreatic cancer growth and predicts poor prognosis.

Published in:

Cellular Oncology (2211-3428), 2020, v. 43, n. 1, p. 51, doi. 10.1007/s13402-019-00435-1

By:

Song, Chao;
Chen, Tianwei;
He, Lan;
Ma, Ning;
Li, Jian-ang;
Rong, Ye-Fei;
Fang, Yuan;
Liu, Mengmeng;
Xie, Dong;
Lou, Wenhui

Publication type:

Article

Regulation of Skeletal Muscle Plasticity by Protein Arginine Methyltransferases and Their Potential Roles in Neuromuscular Disorders.

Published in:

Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00870

By:

Stouth, Derek W.;
vanLieshout, Tiffany L.;
Shen, Nicole Y.;
Ljubicic, Vladimir

Publication type:

Article

PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development.

Published in:

Stem Cells International, 2021, p. 1, doi. 10.1155/2021/6241600

By:

Wang, Bingyuan;
Zhang, Mingrui;
Liu, Zhiguo;
Mu, Yulian;
Li, Kui

Publication type:

Article

Protein methyltransferase 7 deficiency in Leishmania major increases neutrophil associated pathology in murine model.

Published in:

PLoS Neglected Tropical Diseases, 2021, v. 15, n. 3, p. 1, doi. 10.1371/journal.pntd.0009230

By:

Alcoforado Diniz, Juliana;
Chaves, Mariana M.;
Vaselek, Slavica;
Miserani Magalhães, Rubens D.;
Ricci-Azevedo, Rafael;
de Carvalho, Renan V. H.;
Lorenzon, Lucas B.;
Ferreira, Tiago R.;
Zamboni, Dario;
Walrad, Pegine B.;
Volf, Petr;
Sacks, David L.;
Cruz, Angela K.

Publication type:

Article

PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt–β-catenin pathway.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, p. 1, doi. 10.1186/s13046-024-03038-3

By:

Yu, Peng;
Xu, Tutu;
Ma, Wenmeng;
Fang, Xiang;
Bao, Yue;
Xu, Chengran;
Huang, Jinhai;
Sun, Yongqing;
Li, Guangyu

Publication type:

Article

Current and future therapeutic strategies for high-grade gliomas leveraging the interplay between epigenetic regulators and kinase signaling networks.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-023-02923-7

By:

Stitzlein, Lea M.;
Adams, Jack T.;
Stitzlein, Erin N.;
Dudley, Richard W.;
Chandra, Joya

Publication type:

Article

Anoikis resistance and immune escape mediated by Epstein-Barr virus-encoded latent membrane protein 1-induced stabilization of PGC-1α promotes invasion and metastasis of nasopharyngeal carcinoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02835-6

By:

Liao, Chaoliang;
Li, Min;
Chen, Xue;
Tang, Chenpeng;
Quan, Jing;
Bode, Ann M.;
Cao, Ya;
Luo, Xiangjian

Publication type:

Article

Asymmetric and symmetric protein arginine methylation in methionine-addicted human cancer cells.

Published in:

PLoS ONE, 2023, v. 18, n. 12, p. 1, doi. 10.1371/journal.pone.0296291

By:

Holtz, Ashley G.;
Lowe, Troy L.;
Aoki, Yusuke;
Kubota, Yutaro;
Hoffman, Robert M.;
Clarke, Steven G.

Publication type:

Article

The exquisite specificity of human protein arginine methyltransferase 7 (PRMT7) toward Arg-X-Arg sites.

Published in:

PLoS ONE, 2023, v. 18, n. 5, p. 1, doi. 10.1371/journal.pone.0285812

By:

Bondoc, Timothy J.;
Lowe, Troy L.;
Clarke, Steven G.

Publication type:

Article

Cingulate protein arginine methyltransferases 1 regulates peripheral hypersensitivity via fragile X messenger ribonucleoprotein.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1153870

By:

Cheng Wu;
Hui-Fang Shang;
Yong-Jie Wang;
Jing-Hua Wang;
Zhen-Xing Zuo;
Yan-Na Lian;
Li Liu;
Chen Zhang;
Xiang-Yao Li

Publication type:

Article

Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations.

Published in:

Journal of Molecular Modeling, 2022, v. 28, n. 7, p. 1, doi. 10.1007/s00894-022-05125-8

By:

Zhang, Qian;
Zhang, Lun;
Jin, Jia;
Fan, Yaohua;
Wang, Xiaoguang;
Hu, Haofeng;
Ye, Xiaoqing;
Wang, Lei;
Cao, Chenxi;
Ye, Fei

Publication type:

Article

Post‐Translational Modifications of the DUX4 Protein Impact Toxic Function in FSHD Cell Models.

Published in:

Annals of Neurology, 2023, v. 94, n. 2, p. 398, doi. 10.1002/ana.26668

By:

Knox, Renatta N.;
Eidahl, Jocelyn O.;
Wallace, Lindsay M.;
Choudury, Sarah G.;
Rashnonejad, Afrooz;
Daman, Katelyn;
Guggenbiller, Matthew J.;
Saad, Nizar Y.;
Hoover, Michael E.;
Zhang, Liwen;
Branson, Owen E.;
Emerson, Charles P.;
Freitas, Michael A.;
Harper, Scott Q.

Publication type:

Article

Prmt5 deficiency inhibits CD4+ T-cell Klf2/S1pr1 expression and ameliorates EAE disease.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02854-2

By:

Zheng, Yingxia;
Chen, Zheyi;
Zhou, Bingqian;
Chen, Shiyu;
Chen, Ningdai;
Shen, Lisong

Publication type:

Article

PRMT2 silencing regulates macrophage polarization through activation of STAT1 or inhibition of STAT6.

Published in:

BMC Immunology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12865-023-00593-w

By:

Liu, Ting;
Li, Yinjiao;
Xu, Muqiu;
Huang, Hongjun;
Luo, Yan

Publication type:

Article

NF90/NFAR (nuclear factors associated with dsRNA) – a new methylation substrate of the PRMT5-WD45-RioK1 complex.

Published in:

Biological Chemistry, 2022, v. 403, n. 10, p. 907, doi. 10.1515/hsz-2022-0136

By:

Cox, Jan;
Esser, Lea Marie;
Jüdt, Maximilian;
Schmitz, Katharina;
Reiffert, Kaja;
Grimmler, Matthias;
Stork, Björn;
Wesselborg, Sebastian;
Peter, Christoph

Publication type:

Article

Methylation of the nuclear poly(A)-binding protein by type I protein arginine methyltransferases - how and why.

Published in:

Biological Chemistry, 2013, v. 394, n. 8, p. 1029, doi. 10.1515/hsz-2013-0121

By:

Wahle, Elmar;
Moritz, Bodo

Publication type:

Article

Asymmetric Dimethylarginine, an Endogenous NOS Inhibitor, Is Actively Metabolized in Rat Erythrocytes.

Published in:

Bioscience, Biotechnology & Biochemistry, 2012, v. 76, n. 7, p. 1334, doi. 10.1271/bbb.120086

By:

YOKORO, Miyuki;
SUZUKI, Makiko;
MUROTA, Kaeko;
OTSUKA, Chie;
YAMASHITA, Hiromi;
TAKAHASHI, Yoshitaka;
TSUJI, Hideaki;
KIMOTO, Masumi

Publication type:

Article

A gene-encoded FRET fluorescent sensor designed for detecting asymmetric dimethylation levels in vitro and in living cells.

Published in:

Analytical & Bioanalytical Chemistry, 2023, v. 415, n. 8, p. 1411, doi. 10.1007/s00216-023-04541-w

By:

Sun, Xuan;
Chen, Feng;
Zhang, Lili;
Liu, Dan

Publication type:

Article

Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 1, p. 61, doi. 10.1007/s11060-014-1419-0

By:

Han, Xiaosi;
Li, Rong;
Zhang, Wenbin;
Yang, Xiuhua;
Wheeler, Crystal;
Friedman, Gregory;
Province, Paula;
Ding, Qiang;
You, Zhiying;
Fathallah-Shaykh, Hassan;
Gillespie, G.;
Zhao, Xinyang;
King, Peter;
Nabors, L.

Publication type:

Article

Structure-Based Discovery and Biological Assays of a Novel PRMT5 Inhibitor for Non-Small Cell Lung Cancer.

Published in:

Molecules, 2022, v. 27, n. 21, p. 7436, doi. 10.3390/molecules27217436

By:

Chen, Yingqing;
Zhang, Mingyu;
Wu, Anxin;
Yao, Xiaojun;
Wang, Qianqian

Publication type:

Article

Design, Synthesis and Biological Evaluation of Novel and Potent Protein Arginine Methyltransferases 5 Inhibitors for Cancer Therapy.

Published in:

Molecules, 2022, v. 27, n. 19, p. 6637, doi. 10.3390/molecules27196637

By:

Tang, Yixuan;
Huang, Shihui;
Chen, Xingxing;
Huang, Junzhang;
Lin, Qianwen;
Huang, Lei;
Wang, Shuping;
Zhu, Qihua;
Xu, Yungen;
Zou, Yi

Publication type:

Article

Synthesis and Activity of Triazole-Adenosine Analogs as Protein Arginine Methyltransferase 5 Inhibitors.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3779, doi. 10.3390/molecules27123779

By:

Brown, Tyler;
Cao, Mengtong;
Zheng, Y. George

Publication type:

Article

ZNF224 Protein: Multifaceted Functions Based on Its Molecular Partners.

Published in:

Molecules, 2021, v. 26, n. 20, p. 6296, doi. 10.3390/molecules26206296

By:

Cesaro, Elena;
Lupo, Angelo;
Rapuano, Roberta;
Pastore, Arianna;
Grosso, Michela;
Costanzo, Paola

Publication type:

Article

Computational Study of Symmetric Methylation on Histone Arginine Catalyzed by Protein Arginine Methyltransferase PRMT5 through QM/MM MD and Free Energy Simulations.

Published in:

Molecules, 2015, v. 20, n. 6, p. 10032, doi. 10.3390/molecules200610032

By:

Yufei Yue;
Yuzhuo Chu;
Hong Guo

Publication type:

Article

Cisplatin-induced ototoxicity involves interaction of PRMT3 and cannabinoid system.

Published in:

Archives of Toxicology, 2019, v. 93, n. 8, p. 2335, doi. 10.1007/s00204-019-02507-5

By:

Lim, Je-Oh;
Ko, Je-Won;
Shin, Na-Rae;
Jung, Tae-Yang;
Moon, Changjong;
Kim, Hyoung-Chin;
Shin, In-Sik;
Kim, Jong-Choon

Publication type:

Article

Effect of l-arginine methyl ester ( l-NAME) on hormonal profile and estrous cycle length in buffaloes ( Bubalus bubalis).

Published in:

Tropical Animal Health & Production, 2012, v. 44, n. 7, p. 1697, doi. 10.1007/s11250-012-0126-0

By:

Sagar, Pushp;
Prasad, Jai;
Prasad, Shiv;
Gupta, Harihar;
Das, Arup

Publication type:

Article

PRMT7通过调控Notch信号转导通路抑制膀胱癌细胞增殖和迁移.

Published in:

China Oncology, 2023, v. 33, n. 5, p. 437, doi. 10.19401/j.cnki.1007-3639.2023.05.003

By:

王雪梅;
程玉;
齐洁敏

Publication type:

Article

MEP50/PRMT5-mediated methylation activates GLI1 in Hedgehog signalling through inhibition of ubiquitination by the ITCH/NUMB complex.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0275-4

By:

Abe, Yoshinori;
Suzuki, Yosuke;
Kawamura, Kenji;
Tanaka, Nobuyuki

Publication type:

Article