Works about PROTEASOME inhibitors

Results: 1151

Excessive activation-induced cytidine deaminase accumulated by proteasome inhibitors rescues abnormal class switch in activated B-cell-like diffuse large B-cell lymphoma.

Published in:

Experimental & Therapeutic Medicine, 2025, v. 29, n. 6, p. N.PAG, doi. 10.3892/etm.2025.12863

By:

Lv, Zhuangwei;
Xu, Chen;
Wang, Zhenzhen;
Liu, Zixian;
Jiao, Junna

Publication type:

Article

Efficient Synthesis and Biological Evaluation of 1,4-Disubstituted 3-Cyanopyridin-2(1H)-ones as Selective Inhibitors of the Post-Acid Activity of Mammalian 20S Proteasomes.

Published in:

Russian Journal of Organic Chemistry, 2025, v. 61, n. 3, p. 449, doi. 10.1134/S107042802460373X

By:

Karapetyan, L. V.;
Tokmajyan, G. G.;
Melikyan, G. S.;
Bouvier-Durand, M.;
Reboud-Ravaux, M.;
Pham, T. H.

Publication type:

Article

Real-world analysis of treatment patterns, effectiveness, and safety of daratumumab-based regimens in Chinese patients with newly diagnosed or relapsed/refractory multiple myeloma.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-13925-3

By:

Wang, Luqun;
Yang, Wei;
Wang, Yafei;
Niu, Ting;
Fu, Rong;
Zhong, Yuping;
Qian, Wenbin;
Ding, Kaiyang;
Sun, Kai;
Liu, Hong;
Fang, Baijun;
Liu, Hui;
Li, Yanhui;
Yang, Yishen;
Zhuo, Jianmin;
Chen, Xi;
Cui, Canchan;
Lu, Jin

Publication type:

Article

Haploidentical Hematopoietic Stem Cell Transplantation for Relapsed/Refractory Extramedullary Multiple Myeloma: A Conditioning Regimen Combining Selinexor and Helical Tomotherapy—A Case Report and Literature Review.

Published in:

Journal of Blood Medicine, 2025, v. 16, p. 177, doi. 10.2147/JBM.S495256

By:

Chen, Bin;
Guo, Rongrong;
Niu, Yanyan;
Guo, Wei;
Wang, Tao

Publication type:

Article

Effects of bortezomib on intracellular antioxidant and apoptosis in HepG2cells.

Published in:

PeerJ, 2025, p. 1, doi. 10.7717/peerj.19235

By:

Świderska-Kołacz, Grażyna;
Madej, Magdalena;
Zmorzynski, Szymon;
Styk, Wojciech;
Surowiec, Iwona;
Witek, Bożena;
Wojciechowska, Anna;
Czerwik-Marcinkowska, Joanna;
Nowakowska, Anna

Publication type:

Article

Long-lasting effect of belantamab mafodotin in heavily pretreated multiple myeloma.

Published in:

2022

By:

Gil-Sierra, Manuel;
Briceño-Casado, Maria;
Julia-Luna, Francisco;
Martinez-Moya, Maria

Publication type:

Case Study

Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance.

Published in:

PLoS Biology, 2015, v. 13, n. 4, p. 1, doi. 10.1371/journal.pbio.1002132

By:

Dogovski, Con;
Xie, Stanley C.;
Burgio, Gaetan;
Bridgford, Jess;
Mok, Sachel;
McCaw, James M.;
Chotivanich, Kesinee;
Kenny, Shannon;
Gnädig, Nina;
Straimer, Judith;
Bozdech, Zbynek;
Fidock, David A.;
Simpson, Julie A.;
Dondorp, Arjen M.;
Foote, Simon;
Klonis, Nectarios;
Tilley, Leann

Publication type:

Article

Development of Potent and Highly Selective Epoxyketone‐Based Plasmodium Proteasome Inhibitors.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 20, p. 1, doi. 10.1002/chem.202203958

By:

Almaliti, Jehad;
Fajtová, Pavla;
Calla, Jaeson;
LaMonte, Gregory M.;
Feng, Mudong;
Rocamora, Frances;
Ottilie, Sabine;
Glukhov, Evgenia;
Boura, Evzen;
Suhandynata, Raymond T.;
Momper, Jeremiah D.;
Gilson, Michael K.;
Winzeler, Elizabeth A.;
Gerwick, William H.;
O'Donoghue, Anthony J.

Publication type:

Article

Ein systematischer Vergleich peptidischer Proteasominhibitoren unterstreicht α-Ketoamid als vielversprechende elektrophile Leitstruktur.

Published in:

Angewandte Chemie, 2014, v. 126, n. 6, p. 1705, doi. 10.1002/ange.201308984

By:

Stein, Martin L.;
Cui, Haissi;
Beck, Philipp;
Dubiella, Christian;
Voss, Constantin;
Krüger, Achim;
Schmidt, Boris;
Groll, Michael

Publication type:

Article

Inhibition of autophagy by autophagic inhibitors enhances apoptosis induced by bortezomib in non-small cell lung cancer cells.

Published in:

Biotechnology Letters, 2014, v. 36, n. 6, p. 1171, doi. 10.1007/s10529-014-1470-0

By:

Wu, Guodong;
Li, Haifeng;
Ji, Zhiyong;
Jiang, Xiaoming;
Lei, Yu;
Sun, Mingli

Publication type:

Article

Transcriptome Guided Drug Combination Suppresses Proliferation of Breast Cancer Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 6, p. 656, doi. 10.1007/s10517-019-04412-4

By:

Shkurnikov, M. Yu.;
Poloznikov, A. A.;
Nikulin, S. V.;
Schumacher, U.;
Wicklein, D.;
Stürken, C.;
Galatenko, V. V.;
Alekseev, B. Ya.

Publication type:

Article

Transcriptome Guided Drug Combination Suppresses Proliferation of Breast Cancer Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 5, p. 656, doi. 10.1007/s10517-019-04412-4

By:

Shkurnikov, M. Yu.;
Poloznikov, A. A.;
Nikulin, S. V.;
Schumacher, U.;
Wicklein, D.;
Stürken, C.;
Galatenko, V. V.;
Alekseev, B. Ya.

Publication type:

Article

Carfilzomib: a novel agent for multiple myeloma.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 8, p. 1095, doi. 10.1111/jphp.12072

By:

Redic, Kimberly

Publication type:

Article

Comparison of antiproliferative and apoptotic effects of a novel proteasome inhibitor MLN2238 with bortezomib on K562 chronic myeloid leukemia cells.

Published in:

Immunopharmacology & Immunotoxicology, 2016, v. 38, n. 2, p. 87, doi. 10.3109/08923973.2015.1122616

By:

Engür, Selin;
Dikmen, Miriş;
Öztürk, Yusuf

Publication type:

Article

蓝光和蛋白酶体抑制剂 MG132 处理对蛹虫草 Cmfrq、Cmwc-1 和 Cmwc-2 转录水平的影响.

Published in:

Mycosystema, 2022, v. 41, n. 4, p. 587, doi. 10.13346/j.mycosystema.210352

By:

丰磊;
李晓然;
付鸣佳;
黄紫妍;
魏伟群;
肖世平

Publication type:

Article

蓝光和蛋白酶体抑制剂MG132 对蛹虫草形态的影响.

Published in:

Mycosystema, 2021, v. 40, n. 11, p. 2953, doi. 10.13346/j.mycosystema.210160

By:

丰磊;
李晓然;
付鸣佳;
黄紫妍;
魏伟群;
肖世平

Publication type:

Article

ERCC1 abundance is an indicator of DNA repair-apoptosis decision upon DNA damage.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01817-7

By:

Erdemir Sayan, Sule;
Sreekumar, Rahul;
Bhome, Rahul;
Mirnezami, Alex;
Yagci, Tamer;
Sayan, A. Emre

Publication type:

Article

Carfilzomib experience in relapsed/refractory multiple myeloma: a single-center experience.

Published in:

Turkish Journal of Medical Sciences, 2018, v. 48, n. 1, p. 80, doi. 10.3906/sag-1611-97

By:

UYSAL, Ayşe;
AKAD SOYER, Nur;
ÖZKAN, Melda;
ŞAHİN, Fahri;
VURAL, Filiz;
TÖBÜ, Mahmut;
TOMBULOĞLU, Murat;
SAYDAM, Güray

Publication type:

Article

The combined effects of proteasome inhibitor bortezomib with topoisomerase I and II inhibitors on topoisomerase enzymes.

Published in:

Turkish Journal of Medical Sciences, 2016, v. 46, n. 6, p. 1882, doi. 10.3906/sag-1511-184

By:

ÖKSÜZOĞLU, Emine;
TIRINOĞLU, Çiydem;
KERİMOĞLU, Barış

Publication type:

Article

ЛЕЧЕНИЕ НА НОВОДИАГНОСТИЦИРАНИ ПАЦИЕНТИ С МИЕЛОМНА БОЛЕСТ - МИНАЛО, НАСТОЯЩЕ, БЪДЕЩЕ

Published in:

General Medicine / Obsta Medicina, 2024, v. 26, n. 6, p. 29

By:

Геров, В.;
Герова, Д.

Publication type:

Article

Bispecific antibodies in multiple myeloma.

Published in:

Acta Haematologica Polonica, 2025, v. 56, n. 1, p. 39, doi. 10.5603/ahp.104091

By:

Bieliński, Krzysztof;
Puła, Bartosz

Publication type:

Article

SARS-CoV-2 infection in patients with multiple myeloma: survey in 23 centers across Europe and USA.

Published in:

Acta Haematologica Polonica, 2023, v. 54, n. 2, p. 82, doi. 10.5603/AHP.a2023.0016

By:

Dytfeld, Dominik;
Radocha, Jakub;
Hajek, Roman;
Cengiz-Seval, Guldane;
Berkac, Meral;
Coriu, Daniel;
Derman, Benjamin;
Jakubowiak, Andrzej;
Peceliunas, Valdas;
Mikala, Gabor;
Bołkun, Łukasz;
Hawrylecka, Dorota;
Grosicki, Sebastian;
Tyczyńska, Agata;
Zaucha, Jan Maciej;
Knopińska, Wanda;
Semeńczuk, Grażyna;
Morawska, Marta;
Giannopoulos, Krzysztof;
Puła, Anna

Publication type:

Article

Early recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91678

By:

Ibtisam, Ibtisam;
Kisselev, Alexei F.

Publication type:

Article

High-content microscopy reveals a morphological signature of bortezomib resistance.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.91362

By:

Kelley, Megan E.;
Berman, Adi Y.;
Stirling, David R.;
Cimini, Beth A.;
Yu Han;
Singh, Shantanu;
Carpenter, Anne E.;
Kapoor, Tarun M.;
Way, Gregory P.

Publication type:

Article

Adjuvant drug-assisted bone healing: Part III – Further strategies for local and systemic modulation.

Published in:

Clinical Hemorheology & Microcirculation, 2019, v. 73, n. 3, p. 439, doi. 10.3233/CH-199104

By:

Rothe, Rebecca;
Schulze, Sabine;
Neuber, Christin;
Hauser, Sandra;
Rammelt, Stefan;
Pietzsch, Jens;
Pietzsch, J.;
Jung, F.

Publication type:

Article

ATP-based cell viability assay is superior to trypan blue exclusion and XTT assay in measuring cytotoxicity of anticancer drugs Taxol and Imatinib, and proteasome inhibitor MG-132 on human hepatoma cell line HepG2.

Published in:

Clinical Hemorheology & Microcirculation, 2018, v. 69, n. 1-2, p. 327, doi. 10.3233/CH-189120

By:

Nowak, Elisabeth;
Kammerer, Sarah;
Küpper, Jan-Heiner

Publication type:

Article

Biological research on the occurrence and development of multiple myeloma and its treatment.

Published in:

Immunity, Inflammation & Disease, 2023, v. 11, n. 5, p. 1, doi. 10.1002/iid3.850

By:

Wu, Yue;
Shi, Xiangjun;
Yao, Xinchen;
Du, Xinru

Publication type:

Article

Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels.

Published in:

Cancer Biology & Medicine, 2019, v. 16, n. 2, p. 221, doi. 10.20892/j.issn.2095-3941.2018.0235

By:

Na Li;
Ting Wang;
Zongmeng Li;
Xiaoli Ye;
Bo Deng;
Shu Zhuo;
Pengle Yao;
Mengmei Yang;
Hong Mei;
Xiaofang Chen;
Tengfei Zhu;
Shiting Chen;
Hui Wang;
Jiming Wang;
Yingying Le

Publication type:

Article

Desensitization With Proteasome Inhibition and Costimulation Blockade Modulates the Xenoreactive Humoral Response in Nonhuman Primate Xenotransplantation.

Published in:

Xenotransplantation, 2025, v. 32, n. 2, p. 1, doi. 10.1111/xen.70045

By:

Lovasik, Brendan P.;
Matar, Abraham J.;
Habib, Jakob;
Faber, David A.;
Breeden, Cynthia P.;
Farris, Alton B.;
Tector, A. Joseph;
Adams, Andrew B.

Publication type:

Article

Minimal effect of bortezomib in reducing anti-pig antibodies in human leukocyte antigen-sensitized patients: a pilot study.

Published in:

Xenotransplantation, 2013, v. 20, n. 6, p. 429, doi. 10.1111/xen.12052

By:

Hara, Hidetaka;
Bentall, Andrew;
Long, Cassandra;
Fang, Jason;
Andreyev, Oleg;
Lunz, John;
Ezzelarab, Mohamed;
Abu‐Elmagd, Kareem M.;
Shapiro, Ron;
Ayares, David;
Stegall, Mark;
Cooper, David K. C.

Publication type:

Article

Mini-Orals 1 & 2.

Published in:: Xenotransplantation, 2013, v. 20, n. 5, p. 330, doi. 10.1111/xen.12060_10
Publication type:: Article

REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.

Published in:

Experimental Dermatology, 2017, v. 26, n. 11, p. 1118, doi. 10.1111/exd.13394

By:

Chen, Hui;
Gao, Xiao;
Sun, Zhengwang;
Wang, Qingwei;
Zuo, Di;
Pan, Linian;
Li, Kun;
Chen, Jiwei;
Chen, Geng;
Hu, Kewen;
Li, Ke;
Shah, Abdus Saboor;
Huang, Tingmei;
Muhammad Zeeshan, Bhatti;
Tong, Lu;
Jiao, Chan;
Liu, Jian;
Chen, Tenghui;
Yao, Liangfang;
Dang, Yongyan

Publication type:

Article

Opposing effects on immune function and skin barrier regulation by the proteasome inhibitor bortezomib in an allergen-induced eczema model.

Published in:

Experimental Dermatology, 2013, v. 22, n. 11, p. 742, doi. 10.1111/exd.12261

By:

Mudnakudu Nagaraju, Kiran Kumar;
Babina, Magda;
Worm, Margitta

Publication type:

Article

Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43121-x

By:

Byers, Holly A.;
Brooks, Amy N.;
Vangala, Janakiram R.;
Grible, Jacqueline M.;
Feygin, Alex;
Clevenger, Charles V.;
Harrell, J. Chuck;
Radhakrishnan, Senthil K.

Publication type:

Article

Regulation of TRIB1 abundance in hepatocyte models in response to proteasome inhibition.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-36512-7

By:

Soubeyrand, Sébastien;
Lau, Paulina;
McPherson, Ruth

Publication type:

Article

Factors determining the sensitivity to proteasome inhibitors of multiple myeloma cells.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1351565

By:

Pelon, Marta;
Krzeminski, Patryk;
Tracz-Gaszewska, Zuzanna;
Misiewicz-Krzeminska, Irena

Publication type:

Article

Proteasome Inhibitor YSY01A Abrogates Constitutive STAT3 Signaling via Down-regulation of Gp130 and JAK2 in Human A549 Lung Cancer Cells.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00476

By:

Wei Huang;
Xia Yuan;
Ting Sun;
Shujie Fan;
Jun Wang;
Quan Zhou;
Wei Guo;
Fuxiang Ran;
Zemei Ge;
Huayu Yang;
Runtao Li;
Jingrong Cui

Publication type:

Article

Production of Epoxyketone Peptide-Based Proteasome Inhibitors by Streptomyces sp. BRA-346: Regulation and Biosynthesis.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.786008

By:

Domingues Vieira, Bruna;
Niero, Henrique;
de Felício, Rafael;
Giolo Alves, Luiz Fernando;
Freitas Bazzano, Cristina;
Sigrist, Renata;
Costa Furtado, Luciana;
Felix Persinoti, Gabriela;
Veras Costa-Lotufo, Leticia;
Barretto Barbosa Trivella, Daniela

Publication type:

Article

Viral entry and the ubiquitin‐proteasome system.

Published in:

Cellular Microbiology, 2021, v. 23, n. 2, p. 1, doi. 10.1111/cmi.13276

By:

Schneider, Seth M.;
Lee, Becky H.;
Nicola, Anthony V.

Publication type:

Article

EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface.

Published in:

Oncogene, 2015, v. 34, n. 11, p. 1375, doi. 10.1038/onc.2014.88

By:

Adams, M N;
Harrington, B S;
He, Y;
Davies, C M;
Wallace, S J;
Chetty, N P;
Crandon, A J;
Oliveira, N B;
Shannon, C M;
Coward, J I;
Lumley, J W;
Perrin, L C;
Armes, J E;
Hooper, J D

Publication type:

Article

A Phase II Study to Evaluate the Efficacy of Bortezomib in Combination with Thalidomide in Treatment-Naïve Waldenstrom Macroglobulinemia Patients.

Published in:

Cancer Research & Treatment, 2024, v. 56, n. 2, p. 675, doi. 10.4143/crt.2023.681

By:

Byun, Ja Min;
Shin, Junghoon;
Kim, Sang-A;
Park, Hyunkyung;
Lee, Jiyun;
Shin, Dong-Yeop;
Hong, Junshik;
Lee, Jeong-Ok;
Bang, Soo-Mee;
Kim, Inho;
Yoon, Sung-Soon;
Koh, Youngil

Publication type:

Article

Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-44077-2

By:

Hsu, Hao-Chi;
Li, Daqiang;
Zhan, Wenhu;
Ye, Jianxiang;
Liu, Yi Jing;
Leung, Annie;
Qin, Junling;
Crespo, Benigno;
Gamo, Francisco-Javier;
Zhang, Hao;
Cui, Liwang;
Roth, Alison;
Kirkman, Laura A.;
Li, Huilin;
Lin, Gang

Publication type:

Article

Allosteric regulation of the 20S proteasome by the Catalytic Core Regulators (CCRs) family.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38404-w

By:

Deshmukh, Fanindra Kumar;
Ben-Nissan, Gili;
Olshina, Maya A.;
Füzesi-Levi, Maria G.;
Polkinghorn, Caley;
Arkind, Galina;
Leushkin, Yegor;
Fainer, Irit;
Fleishman, Sarel J.;
Tawfik, Dan;
Sharon, Michal

Publication type:

Article

HDAC6: A unique HDAC family member as a cancer target.

Published in:

Cellular Oncology (2211-3428), 2022, v. 45, n. 5, p. 779, doi. 10.1007/s13402-022-00704-6

By:

Kaur, Sumeet;
Rajoria, Prerna;
Chopra, Madhu

Publication type:

Article

Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones.

Published in:

Cellular Oncology (2211-3428), 2018, v. 41, n. 6, p. 623, doi. 10.1007/s13402-018-0397-1

By:

Contreras, Lisett;
Calderon, Ruben I.;
Varela-Ramirez, Armando;
Zhang, Hong-Yu;
Quan, Yuan;
Das, Umashankar;
Dimmock, Jonathan R.;
Skouta, Rachid;
Aguilera, Renato J.

Publication type:

Article

Visualizing Mutation-Specific Differences in the Trafficking-Deficient Phenotype of Kv11.1 Proteins Linked to Long QT Syndrome Type 2.

Published in:

Frontiers in Physiology, 2018, p. 1, doi. 10.3389/fphys.2018.00584

By:

Hall, Allison R.;
Anderson, Corey L.;
Smith, Jennifer L.;
Mirshahi, Tooraj;
Elayi, Claude S.;
January, Craig T.;
Delisle, Brian P.

Publication type:

Article

Pulmonary Nocardiosis in a Multiple Myeloma Patient Treated with Proteasome Inhibitors.

Published in:

2016

By:

Mendonca, Nikolai P.;
Kadayakkara, Deepak K.;
Forde, Inga C.;
Rudkovaskaia, Anastasiia;
Saul, Zane K.;
Lobo, David J.

Publication type:

Case Study

ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation.

Published in:

Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13287-020-02037-3

By:

Zhang, Dan;
De Veirman, Kim;
Fan, Rong;
Jian, Qiang;
Zhang, Yuchen;
Lei, Li;
Evans, Holly;
Wang, Yanmeng;
Lei, Lei;
Wang, Baiyan;
Williamson, Ramone A.;
Chantry, Andrew;
He, Pengcheng;
Li, Ang;
De Raeve, Hendrik;
Vanderkerken, Karin;
He, Aili;
Hu, Jinsong

Publication type:

Article

Molecularly Targeted Therapies in Multiple Myeloma.

Published in:

Leukemia Research & Treatment, 2014, p. 1, doi. 10.1155/2014/976567

By:

de la Puente, Pilar;
Muz, Barbara;
Azab, Feda;
Luderer, Micah;
Azab, Abdel Kareem

Publication type:

Article

Paradoxical inhibition of cellular protein expression by proteasome inhibitors.

Published in:

Biomolecular Concepts, 2012, v. 3, n. 6, p. 593, doi. 10.1515/bmc-2012-0029

By:

Gartel, Andrei L.

Publication type:

Article