Works about PROTEASE-activated receptors

Results: 477

The Influence of Anti-PAR 1 and Anti-ACE 2 Antibody Levels on the Course of Specific Glomerulonephritis Types.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 9, p. 3178, doi. 10.3390/jcm14093178

By:

Szymczak, Maciej;
Heidecke, Harald;
Żabińska, Marcelina;
Janek, Łucja;
Wronowicz, Jakub;
Kujawa, Krzysztof;
Schulze-Forster, Kai;
Marek-Bukowiec, Karolina;
Gołębiowski, Tomasz;
Banasik, Mirosław

Publication type:

Article

PARticularly Forceful: PAR1 Drives Glomerular Mesangial Cell Contractility.

Published in:

Function, 2024, v. 5, n. 6, p. 1, doi. 10.1093/function/zqae044

By:

Waller, Amanda P;
Muralidharan, Kaushik;
Kerlin, Bryce A

Publication type:

Article

Exogenous Activation of Protease-Activated Receptor 2 Attenuates Cutaneous Vasodilatation and Sweating in Older Men Exercising in the Heat.

Published in:

Skin Pharmacology & Physiology, 2019, v. 32, n. 5, p. 235, doi. 10.1159/000500643

By:

Fujii, Naoto;
Hatam, Kion;
McGarr, Gregory W.;
Meade, Robert D.;
Boulay, Pierre;
Nishiyasu, Takeshi;
Kenny, Glen P.

Publication type:

Article

Edoxaban suppresses the progression of atrial fibrosis and atrial fibrillation in a canine congestive heart failure model.

Published in:

Heart & Vessels, 2019, v. 34, n. 8, p. 1381, doi. 10.1007/s00380-019-01377-2

By:

Tsujino, Yasushi;
Sakamoto, Tamotsu;
Kinoshita, Koshi;
Nakatani, Yosuke;
Yamaguchi, Yoshiaki;
Kataoka, Naoya;
Nishida, Kunihiro;
Kinugawa, Koichiro

Publication type:

Article

Protease-activated receptors and their biological role -- focused on skin inflammation.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 12, p. 1623, doi. 10.1111/jphp.12447

By:

Guenther, Florian;
Melzig, Matthias F.

Publication type:

Article

Changes in Protease-Activated Receptor and Trypsin-1 Expression Are Involved in the Therapeutic Effect of Mg<sup>2+</sup> Supplementation in Type 2 Diabetes-Induced Gastric Injury in Male Adult Rats.

Published in:

Advances in Pharmacological & Pharmaceutical Sciences, 2023, p. 1, doi. 10.1155/2023/5703718

By:

Mehranfard, Nasrin;
Rezazadeh, Hossein;
Soltani, Nepton;
Dastgerdi, Azadesadat Hosseini;
Ghanbari Rad, Mahtab;
Ghasemi, Maedeh

Publication type:

Article

The effect of exogenous activation of protease-activated receptor 2 on cutaneous vasodilatation and sweating in young males during rest and exercise in the heat.

Published in:

Temperature, 2018, v. 5, n. 3, p. 257, doi. 10.1080/23328940.2018.1506563

By:

Danquah, Mercy O.;
Meade, Robert D.;
Kenny, Glen P.;
Fujii, Naoto;
Nishiyasu, Takeshi

Publication type:

Article

Defect in Sensing Human Thrombin by Porcine Endothelial Protease‐Activated Receptor‐1: Molecular Incompatibility Between Porcine PAR‐1 and Human Thrombin.

Published in:

Xenotransplantation, 2025, v. 32, n. 2, p. 1, doi. 10.1111/xen.70041

By:

Hoang, Thi Xoan;
Bang, Ju‐Young;
Nguyen, Vinh Phuoc;
Vu, Phu Chi;
Yun, Ik Jin;
Kang, Hee Jung;
Kim, Jae Young

Publication type:

Article

The involvement of keratinocytes in pruritus of chronic inflammatory dermatosis.

Published in:

Experimental Dermatology, 2024, v. 33, n. 7, p. 1, doi. 10.1111/exd.15142

By:

Lin, Shiying;
Liu, Xin;
Jiang, Jian;
Ge, Wenqiang;
Zhang, Yinlian;
Li, Fei;
Tao, Qingxiao;
Liu, Suwen;
Li, Man;
Chen, Hongxiang

Publication type:

Article

House dust mite‐treated PAR2 over‐expressor mouse: A novel model of atopic dermatitis.

Published in:

Experimental Dermatology, 2019, v. 28, n. 11, p. 1298, doi. 10.1111/exd.14030

By:

Smith, Leila;
Gatault, Solene;
Casals‐Diaz, Laura;
Kelly, Pamela A.;
Camerer, Eric;
Métais, Charles;
Knaus, Ulla G.;
Eissner, Günther;
Steinhoff, Martin

Publication type:

Article

Update on protease‐activated receptor 2 in cutaneous barrier, differentiation, tumorigenesis and pigmentation, and its role in related dermatologic diseases.

Published in:

Experimental Dermatology, 2019, v. 28, n. 8, p. 877, doi. 10.1111/exd.13936

By:

Henehan, Mason;
De Benedetto, Anna

Publication type:

Article

Upregulation of protease-activated receptor-2 in keratinocytes by epidermal vascular endothelial growth factor in vitro and in vivo.

Published in:

Experimental Dermatology, 2017, v. 26, n. 3, p. 286, doi. 10.1111/exd.13183

By:

Lee, Si‐Hyung;
Kim, Ji Min;
Lee, Sang Eun;
Jeong, Se Kyoo;
Lee, Seung Hun

Publication type:

Article

Effects of PAR2 antagonist on inflammatory signals and tight junction expression in protease-activated canine primary epithelial keratinocytes.

Published in:

Experimental Dermatology, 2017, v. 26, n. 1, p. 86, doi. 10.1111/exd.13121

By:

Kim, Ha‐Jung;
Jeong, Se Kyoo;
Hong, Soo‐Jong;
Ahrens, Kim;
Marsella, Rosanna

Publication type:

Article

New light on proteases regulating pigmentation.

Published in:

Experimental Dermatology, 2016, v. 25, n. 11, p. 861, doi. 10.1111/exd.13090

By:

Smith, Leila;
Casals‐Diaz, Laura;
Steinhoff, Martin

Publication type:

Article

Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-48365-1

By:

Silva, Irismara Sousa;
Almeida, Aline D.;
Lima Filho, Antônio C. M.;
Fernandes-Braga, Weslley;
Barra, Ayslan;
Oliveira, Hortência M. C.;
Cassali, Geovanni D.;
Capettini, Luciano S. A.;
Menezes, Gustavo B.;
Alvarez-Leite, Jacqueline I.;
Leite, Maria F.;
Klein, André

Publication type:

Article

YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1205062

By:

Zhan Jing-Lun;
Chai Shuang;
Zhao Li-Mei;
Liu Xiao-Dong

Publication type:

Article

Protease-Activated Receptor-2 Deficiency Attenuates Atherosclerotic Lesion Progression and Instability in Apolipoprotein E-Deficient Mice.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00647

By:

Pengfei Zuo;
Zhi Zuo;
Yueyue Zheng;
Xin Wang;
Qianxing Zhou;
Long Chen;
Genshan Ma

Publication type:

Article

Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00470

By:

Masato Dekita;
Zhou Wu;
Junjun Ni;
Xinwen Zhang;
Yicong Liu;
Xu Yan;
Hiroshi Nakanishi;
Ichiro Takahashi

Publication type:

Article

Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells.

Published in:

Frontiers in Pharmacology, 2017, v. 7, p. 1, doi. 10.3389/fphar.2016.00497

By:

Indrakusuma, Ira;
Romacho, Tania;
Eckel, Jürgen

Publication type:

Article

Coagulation and Skin Autoimmunity.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01407

By:

Cugno, Massimo;
Borghi, Alessandro;
Garcovich, Simone;
Marzano, Angelo Valerio

Publication type:

Article

Protease Activated Receptor 4 as a Novel Modulator of Regulatory T Cell Function.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01311

By:

Peng, Qi;
Ratnasothy, Kulachelvy;
Boardman, Dominic A.;
Jacob, Jacinta;
Tung, Sim Lai;
McCluskey, Daniel;
Smyth, Lesley A.;
Lechler, Robert I.;
Dorling, Anthony;
Lombardi, Giovanna

Publication type:

Article

Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines.

Published in:

Psychopharmacology, 2022, v. 239, n. 1, p. 229, doi. 10.1007/s00213-021-06040-1

By:

Moudio, Serge;
Willis, Ashleigh;
Pytka, Karolina;
Abulkassim, Roua;
Brett, Ros R.;
Webster, Jack F.;
Wozny, Christian;
Barbour, Mark;
Jiang, Hui-Rong;
Watson, David G.;
van Kralingen, Josie C.;
MacKenzie, Scott M.;
Daniels, Michael;
McColl, Barry W.;
Sossick, Sandra;
Nuthall, Hugh N.;
Bushell, Trevor J.

Publication type:

Article

Inhibition of protease-activated receptor 1 (PAR1) ameliorates cognitive performance and synaptic plasticity impairments in animal model of Alzheimer's diseases.

Published in:

Psychopharmacology, 2021, v. 238, n. 6, p. 1645, doi. 10.1007/s00213-021-05798-8

By:

Zare, Daruoosh;
Rajizadeh, Mohammad Amin;
Maneshian, Marzieh;
Jonaidi, Hossein;
Sheibani, Vahid;
Asadi-Shekaari, Majid;
Yousefi, Manouchehr;
Esmaeilpour, Khadijeh

Publication type:

Article

Macrophage-secreted MMP9 induces mesenchymal transition in pancreatic cancer cells via PAR1 activation.

Published in:

Cellular Oncology (2211-3428), 2020, v. 43, n. 6, p. 1161, doi. 10.1007/s13402-020-00549-x

By:

Tekin, Cansu;
Aberson, Hella L;
Waasdorp, Cynthia;
Hooijer, Gerrit K J;
de Boer, Onno J;
Dijk, Frederike;
Bijlsma, Maarten F;
Spek, C Arnold

Publication type:

Article

Host innate immune responses to sepsis.

Published in:

Virulence, 2014, v. 5, n. 1, p. 36, doi. 10.4161/viru.25436

By:

Wiersinga, Willem Joost;
Leopold, Stije J;
Cranendonk, Duncan R;
van der Poll, Tom

Publication type:

Article

Xa inhibitor edoxaban ameliorates hepatic ischemia-reperfusion injury via PAR-2–ERK 1/2 pathway.

Published in:

PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0292628

By:

Maeda, Koki;
Kuriyama, Naohisa;
Noguchi, Daisuke;
Ito, Takahiro;
Gyoten, Kazuyuki;
Hayasaki, Aoi;
Fujii, Takehiro;
Iizawa, Yusuke;
Murata, Yasuhiro;
Tanemura, Akihiro;
Kishiwada, Masashi;
Mizuno, Shugo

Publication type:

Article

New PAR1 Agonist Peptide Demonstrates Protective Action in a Mouse Model of Photothrombosis-Induced Brain Ischemia.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00335

By:

Galkov, Maksim;
Kiseleva, Ekaterina;
Gulyaev, Mikhail;
Sidorova, Maria;
Gorbacheva, Liubov

Publication type:

Article

Expression of Protease Activated Receptor-1 in Chronic Periodontitis.

Published in:

Journal of Periodontology, 2014, v. 85, n. 12, p. 1763, doi. 10.1902/jop.2014.140172

By:

Bueno da Silva, Henrique Aparecido;
Euzebio Alves, Vanessa Tubero;
Spolidório, Luis Carlos;
César Neto, João Batista;
Eichler, Rosangela Santos;
Catelli de Carvalho, Maria Helena;
Holzhausen, Marinella

Publication type:

Article

Porphyromonas Gingivalis is Associated With Protease-Activated Receptor-2 Upregulation in Chronic Periodontitis.

Published in:

Journal of Periodontology, 2011, v. 82, n. 11, p. 1596, doi. 10.1902/jop.2011.110073

By:

Fagundes, José Américo G.;
Monoo, Letícia D.;
Alves, Vanessa Tubero Euzébio;
Pannuti, Cláudio Mendes;
Cortelli, Sheila Cavalca;
Cortelli, José Roberto;
Holzhausen, Marinella

Publication type:

Article

Interleukin-1β Increased the Expression of Protease-Activated Receptor 4 mRNA and Protein in Dorsal Root Ganglion Neurons.

Published in:

Neurochemical Research, 2013, v. 38, n. 9, p. 1895, doi. 10.1007/s11064-013-1095-z

By:

Wang, Zhaojin;
Chen, Dan;
Zhang, Rui;
An, Shuhong;
Zhang, Zaifeng;
Ma, Qingyuan

Publication type:

Article

Protease-Activated Receptor 2 Facilitates Bacterial Dissemination in Pneumococcal Pneumonia.

Published in:

2018

By:

van den Boogaard, Florry E.;
Brands, Xanthe;
Duitman, JanWillem;
de Stoppelaar, Sacha F.;
Borensztajn, Keren S.;
Roelofs, Joris J. T. H.;
Hollenberg, Morley D.;
Spek, C. Arnold;
Schultz, Marcus J.;
Veer, Cornelis van't;
van der Poll, Tom;
van 't Veer, Cornelis

Publication type:

journal article

Enhanced Effector Function of CD8+ T Cells From Healthy Controls and HIV-Infected Patients Occurs Through Thrombin Activation of Protease-Activated Receptor 1.

Published in:

Journal of Infectious Diseases, 2013, v. 207, n. 4, p. 638, doi. 10.1093/infdis/jis730

By:

Hurley, Amanda;
Smith, Mindy;
Karpova, Tatiana;
Hasley, Rebecca B.;
Belkina, Natalya;
Shaw, Stephen;
Balenga, Nariman;
Druey, Kirk M.;
Nickel, Erin;
Packard, Beverly;
Imamichi, Hiromi;
Hu, Zonghui;
Follmann, Dean;
McNally, James;
Higgins, Jeanette;
Sneller, Michael;
Lane, H. Clifford;
Catalfamo, Marta

Publication type:

Article

Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2.

Published in:

Reproductive Biology & Endocrinology, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12958-023-01085-7

By:

Hennes, Aurélie;
Devroe, Johanna;
De Clercq, Katrien;
Ciprietti, Martina;
Held, Katharina;
Luyten, Katrien;
Van Ranst, Nele;
Maenhoudt, Nina;
Peeraer, Karen;
Vankelecom, Hugo;
Voets, Thomas;
Vriens, Joris

Publication type:

Article

The Role of Protease-Activated Receptor 2 in Hepatocellular Carcinoma after Hepatectomy.

Published in:

Medicina (1010660X), 2021, v. 57, n. 6, p. 1, doi. 10.3390/medicina57060574

By:

Tsai, Ming-Chao;
Lin, Chih-Che;
Chen, Ding-Wei;
Liu, Yueh-Wei;
Wu, Yi-Ju;
Yen, Yi-Hao;
Huang, Pao-Yuan;
Yao, Chih-Chien;
Chuang, Ching-Hui;
Hsiao, Chang-Chun

Publication type:

Article

Microenvironment proteinases, proteinase-activated receptor regulation, cancer and inflammation.

Published in:

Biological Chemistry, 2018, v. 399, n. 9, p. 1023, doi. 10.1515/hsz-2018-0001

By:

Eftekhari, Rahil;
de Lima, Stacy G.;
Yu Liu;
Koichiro Mihara;
Saifeddine, Mahmoud;
Noorbakhsh, Farshid;
Scarisbrick, Isobel A.;
Hollenberg, Morley D.

Publication type:

Article

Kallikrein-related peptidase 6 orchestrates astrocyte form and function through proteinase activated receptor-dependent mechanisms.

Published in:

Biological Chemistry, 2018, v. 399, n. 9, p. 1041, doi. 10.1515/hsz-2018-0122

By:

Hyesook Yoon;
Radulovic, Maja;
Scarisbrick, Isobel A.

Publication type:

Article

Factor Xa Inhibition with Apixaban Does Not Influence Cardiac Remodelling in Rats with Heart Failure After Myocardial Infarction.

Published in:

Cardiovascular Drugs & Therapy, 2021, v. 35, n. 5, p. 953, doi. 10.1007/s10557-020-06999-7

By:

Yurista, Salva R.;
Silljé, Herman H. W.;
Nijholt, Kirsten T.;
Dokter, Martin M.;
van Veldhuisen, Dirk J.;
de Boer, Rudolf A.;
Westenbrink, B. Daan

Publication type:

Article

Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19.

Published in:

Cardiovascular Drugs & Therapy, 2021, v. 35, n. 2, p. 195, doi. 10.1007/s10557-020-07066-x

By:

Aliter, Kholoud F.;
Al-Horani, Rami A.

Publication type:

Article

Ticagrelor Inhibits Toll-Like and Protease-Activated Receptor Mediated Platelet Activation in Acute Coronary Syndromes.

Published in:

Cardiovascular Drugs & Therapy, 2020, v. 34, n. 1, p. 53, doi. 10.1007/s10557-019-06932-7

By:

Wadowski, Patricia P.;
Weikert, Constantin;
Pultar, Joseph;
Lee, Silvia;
Eichelberger, Beate;
Koppensteiner, Renate;
Lang, Irene M.;
Panzer, Simon;
Gremmel, Thomas

Publication type:

Article

Paracoccidioides brasiliensis induces cytokine secretion in epithelial cells in a protease-activated receptor-dependent (PAR) manner.

Published in:

Medical Microbiology & Immunology, 2017, v. 206, n. 2, p. 149, doi. 10.1007/s00430-016-0490-x

By:

Oliveira, Priscila;
Juliano, Maria;
Tanaka, Aparecida;
Carmona, Adriana;
Santos, Saara;
Barros, Bianca;
Maza, Paloma;
Puccia, Rosana;
Suzuki, Erika

Publication type:

Article

Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation.

Published in:

Cardiology, 2017, v. 136, n. 4, p. 258, doi. 10.1159/000452269

By:

antoniak, Silvio;
Cardenas, Jessica C.;
Buczek, Laura J.;
Church, Frank C.;
Mackman, Nigel;
Pawlinski, Rafal

Publication type:

Article

The Many Faces of Protease-Activated Receptor 2 in Kidney Injury.

Published in:

Biomedicines, 2025, v. 13, n. 2, p. 414, doi. 10.3390/biomedicines13020414

By:

Oe, Yuji;
Tanaka, Tetsuhiro;
Takahashi, Nobuyuki

Publication type:

Article

Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design.

Published in:

Biomedicines, 2024, v. 12, n. 1, p. 246, doi. 10.3390/biomedicines12010246

By:

Nag, Jeetendra Kumar;
Grisaru-Granovsky, Sorina;
Armon, Shunit;
Rudina, Tatyana;
Appasamy, Priyanga;
Bar-Shavit, Rachel

Publication type:

Article

Tissue Factor, Thrombosis, and Chronic Kidney Disease.

Published in:

Biomedicines, 2022, v. 10, n. 11, p. 2737, doi. 10.3390/biomedicines10112737

By:

Oe, Yuji;
Takahashi, Nobuyuki

Publication type:

Article

Role of Chitinase-3-like Protein 1 in Cardioprotection and Angiogenesis by Post-Infarction Exercise Training.

Published in:

Biomedicines, 2022, v. 10, n. 5, p. 1028, doi. 10.3390/biomedicines10051028

By:

Li, Zhuo;
Wu, Fangnan;
Xi, Lei;
Tian, Zhenjun

Publication type:

Article

Intractable Itch in Atopic Dermatitis: Causes and Treatments.

Published in:

Biomedicines, 2021, v. 9, n. 3, p. 229, doi. 10.3390/biomedicines9030229

By:

Umehara, Yoshie;
Kiatsurayanon, Chanisa;
Trujillo-Paez, Juan Valentin;
Chieosilapatham, Panjit;
Peng, Ge;
Yue, Hainan;
Nguyen, Hai Le Thanh;
Song, Pu;
Okumura, Ko;
Ogawa, Hideoki;
Niyonsaba, François;
Bonamonte, Domenico

Publication type:

Article

Activación concertada de los receptores transmembranales: Repercusiones fisiológicas.

Published in:

TIP Revista Especializada en Ciencias Químico-Biológicas, 2023, v. 26, p. 1, doi. 10.22201/fesz.23958723e.2023.572

By:

Lee-Rivera, Irene;
López, Edith;
López Colomé, Ana María

Publication type:

Article

Activation of PAR4 Upregulates p16 through Inhibition of DNMT1 and HDAC2 Expression via MAPK Signals in Esophageal Squamous Cell Carcinoma Cells.

Published in:

2018

By:

Wang, Ming;
An, Shuhong;
Wang, Diyi;
Ji, Haizhen;
Guo, Xingjing;
Wang, Zhaojin

Publication type:

journal article

Downregulation of iNOS, IL-1 , and P2X7 Expression in Mast Cells via Activation of PAR4 Contributes to the Inhibition of Visceral Hyperalgesia in Rats.

Published in:

2018

By:

Hao, Yanli;
Niu, Hao;
An, Shuhong;
Wang, Ming;
Wang, Zhaojin

Publication type:

journal article

Are testicular mast cells involved in the regulation of germ cells in man?

Published in:

Andrology, 2014, v. 2, n. 4, p. 615, doi. 10.1111/j.2047-2927.2014.00227.x

By:

Windschüttl, S.;
Nettersheim, D.;
Schlatt, S.;
Huber, A.;
Welter, H.;
Schwarzer, J. U.;
Köhn, F. M.;
Schorle, H.;
Mayerhofer, A.

Publication type:

Article