Works matching DE "PROPROTEIN convertases"
Results: 368
The association of serum proprotein convertase furin/PCSK3 concentrations with stable coronary artery disease and coroner artery lesion severity.
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- International Journal of Medical Biochemistry, 2024, v. 7, n. 1, p. 18, doi. 10.14744/ijmb.2023.09326
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- Article
Bioinformatics analysis of bovine neuropeptides.
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- Journal of Animal Science, 2006, v. 84, p. 168
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- Article
FOURIER & PCSK9 RNAi: Towards enhancing durability and efficacy of PCSK9 inhibitors.
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- Global Cardiology Science & Practice, 2017, v. 2017, n. 2, p. 1, doi. 10.21542/gcsp.2017.13
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- Article
The PCSK9 revolution and the potential of PCSK9-based therapies to reduce LDL-cholesterol.
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- Global Cardiology Science & Practice, 2015, v. 2015, n. 4, p. 1, doi. 10.5339/gcsp.2015.59
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- Article
OSLER and ODYSSEY LONG TERM: PCSK9 inhibitors on the right track of reducing cardiovascular events.
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- Global Cardiology Science & Practice, 2015, v. 2015, n. 2, p. 1, doi. 10.5339/gcsp.2015.20
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- Article
GAUSS-2, RUTHERFORD-2, LAPLACE-2, DESCARTES, and TESLA Part B: PCSK9 inhibitors gain momentum.
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- Global Cardiology Science & Practice, 2014, v. 2014, n. 4, p. 184, doi. 10.5339/gcsp.2014.49
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- Article
The discovery of PCSK9 inhibitors: A tale of creativity and multifaceted translational research.
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- 2013
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- Editorial
With blood in the joint - what happens next? Could activation of a pro-inflammatory signalling axis leading to iRhom2/TNFα-convertase-dependent release of TNFα contribute to haemophilic arthropathy?
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- Haemophilia, 2014, v. 20, p. 11, doi. 10.1111/hae.12416
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- Article
Serum properdin consumption as a biomarker of C5 convertase dysregulation in C3 glomerulopathy.
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- Clinical & Experimental Immunology, 2016, v. 184, n. 1, p. 118, doi. 10.1111/cei.12754
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- Article
A novel method for direct measurement of complement convertases activity in human serum.
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- Clinical & Experimental Immunology, 2014, v. 178, n. 1, p. 142, doi. 10.1111/cei.12388
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- Article
Are PCSK9 Inhibitors Cost Effective?
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- 2018
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- journal article
Budget Impact Analysis of PCSK9 Inhibitors for the Management of Adult Patients with Heterozygous Familial Hypercholesterolemia or Clinical Atherosclerotic Cardiovascular Disease.
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- 2018
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- journal article
PCSK9 Inhibitors: A Technology Worth Paying For?
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- 2016
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- Publication type:
- Editorial
The Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Nonfasting Remnant Cholesterol in a Real World Population.
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- Journal of Lipids, 2018, p. 1, doi. 10.1155/2018/9194736
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- Article
Serum PCSK9 Levels Distinguish Individuals Who Do Not Respond to High-Dose Statin Therapy with the Expected Reduction in LDL-C.
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- Journal of Lipids, 2014, p. 1, doi. 10.1155/2014/140723
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- Article
Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice.
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- Journal of Lipids, 2013, p. 1, doi. 10.1155/2013/908048
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- Article
Prolonged stress alters the PC1/PC2 ratio in the rat lateral hypothalamus, implicating impaired orexin maturation.
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- Iranian Journal of Basic Medical Sciences, 2024, v. 27, n. 8, p. 1059, doi. 10.22038/IJBMS.2024.76858.16620
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- Article
Proprotein Convertase Subtilisin/Kexin Type 9 Is Associated with Degenerating Adipocytes in Abdominal Aortic Aneurysm.
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- Journal of Oleo Science, 2018, v. 67, n. 10, p. 1355, doi. 10.5650/jos.ess18131
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- Article
New Drug to Lower LDL Cholesterol.
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- JAMA: Journal of the American Medical Association, 2015, v. 314, n. 9, p. 867, doi. 10.1001/jama.2015.10491
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- Article
Molecular characterization and spatiotemporal expression of prohormone convertase 2 in the Pacific abalone, Haliotis discus hannai.
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- PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0231353
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- Article
Characterisation of early metazoan secretion through associated signal peptidase complex subunits, prohormone convertases and carboxypeptidases of the marine sponge (Amphimedon queenslandica).
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- PLoS ONE, 2019, v. 14, n. 11, p. 1, doi. 10.1371/journal.pone.0225227
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- Article
PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort.
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- PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0210808
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- Article
Progastrin processing differs in 7B2 and PC2 knockout animals: a role for 7B2 independent of action on PC2.
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- FEBS Letters, 2002, v. 510, n. 1-2, p. 89, doi. 10.1016/S0014-5793(01)03234-3
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- Article
Mouse Models of Human Proprotein Convertase Insufficiency.
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- Endocrine Reviews, 2021, v. 42, n. 3, p. 259, doi. 10.1210/endrev/bnaa033
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- Article
Pcsk9 Knockout Aggravated Experimental Apical Periodontitis via LDLR.
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- Journal of Dental Research, 2022, v. 101, n. 1, p. 83, doi. 10.1177/00220345211015128
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- Article
Inclisiran Lowers LDL-C and PCSK9 Irrespective of Diabetes Status: The ORION-1 Randomized Clinical Trial.
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- 2019
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- Publication type:
- journal article
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors and Incident Type 2 Diabetes: A Systematic Review and Meta-analysis With Over 96,000 Patient-Years.
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- 2018
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- Publication type:
- journal article
PCSK9 Is Increased in Youth With Type 1 Diabetes.
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- 2017
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- Publication type:
- Letter
The associations between proprotein convertase subtilisin/kexin type 9 E670G polymorphism and the risk of coronary artery disease and serum lipid levels: a meta-analysis.
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- Lipids in Health & Disease, 2015, v. 14, p. 1, doi. 10.1186/s12944-015-0154-7
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- Article
Impact of currently prescribed lipid-lowering drugs on plasma PCSK9 concentration: single or in combination study in rats.
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- Lipids in Health & Disease, 2014, v. 13, n. 1, p. 2, doi. 10.1186/1476-511X-13-35
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- Article
Differential effects of PCSK9 loss of function variants on serum lipid and PCSK9 levels in Caucasian and African Canadian populations.
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- Lipids in Health & Disease, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1476-511X-12-70
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- Article
MG132, a proteasome inhibitor, enhances LDL uptake in HepG2 cells in vitro by regulating LDLR and PCSK9 expression.
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- Acta Pharmacologica Sinica, 2014, v. 35, n. 8, p. 994, doi. 10.1038/aps.2014.52
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- Article
Cellular response to small molecules that selectively stall protein synthesis by the ribosome.
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- PLoS Genetics, 2019, v. 15, n. 3, p. 1, doi. 10.1371/journal.pgen.1008057
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- Article
Non-cross-linking advanced glycation end products affect prohormone processing.
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- Biochemical Journal, 2024, v. 481, n. 1, p. 33, doi. 10.1042/BCJ20230321
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- Article
Stigmasterol accumulation causes cardiac injury and promotes mortality.
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- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0245-x
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- Article
A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.
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- Human Genetics, 2015, v. 134, n. 6, p. 627, doi. 10.1007/s00439-015-1546-5
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- Article
Gain of function mutant of complement factor B K323E mimics pathogenic C3NeF autoantibodies in convertase assays.
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- Autoimmunity, 2018, v. 51, n. 1, p. 18, doi. 10.1080/08916934.2017.1423286
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- Article
Label-Free Electrochemical Test of Protease Interaction with a Peptide Substrate Modified Gold Electrode.
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- Chemosensors, 2021, v. 9, n. 8, p. 199, doi. 10.3390/chemosensors9080199
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- Article
What Are the Roles of Proprotein Convertases in the Immune Escape of Tumors?
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- Biomedicines, 2022, v. 10, n. 12, p. 3292, doi. 10.3390/biomedicines10123292
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- Article
Hemodynamic effects of renin-angiotensin-aldosterone inhibitor and μ-blocker combination therapy vs. μ-blocker monotherapy for portal hypertension in cirrhosis: A meta-analysis.
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- Experimental & Therapeutic Medicine, 2017, v. 13, n. 5, p. 1977, doi. 10.3892/etm.2017.4210
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- Article
Comparative evaluation of copeptin and NT-proBNP in patients with severe acute decompensated heart failure, and prediction of adverse events in a 90-day follow-up period: A prospective clinical observation trial.
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- Experimental & Therapeutic Medicine, 2017, v. 13, n. 4, p. 1554, doi. 10.3892/etm.2017.4111
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- Article
PCSK9 as a therapeutic target for cardiovascular disease (Review).
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- Experimental & Therapeutic Medicine, 2017, v. 13, n. 3, p. 810, doi. 10.3892/etm.2017.4055
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- Article
Relative levels of the proprotein and cleavage-activated form of circulating human anti-Müllerian hormone are sexually dimorphic and variable during the life cycle.
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- Physiological Reports, 2016, v. 4, n. 9, p. n/a, doi. 10.14814/phy2.12783
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- Article
Vitamin D, the autonomic nervous system, and cardiovascular risk.
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- 2015
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- Publication type:
- Editorial
The ventral peptidergic system of the adult ascidian Ciona robusta (Ciona intestinalis Type A) insights from a transgenic animal model.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-58884-w
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- Article
Anti-PCSK9 antibodies inhibit pro-atherogenic mechanisms in APOE*3Leiden.CETP mice.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47242-0
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- Article
Functional Characterization of Alternative and Classical Pathway C3/C5 Convertase Activity and Inhibition Using Purified Models.
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- Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01691
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- Article
Overactivity of Alternative Pathway Convertases in Patients With Complement-Mediated Renal Diseases.
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- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00612
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- Article
Is there a link between proprotein convertase PC7 activity and human lipid homeostasis?
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- FEBS Open Bio, 2014, v. 4, p. 741, doi. 10.1016/j.fob.2014.08.004
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- Article
Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture.
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- FEBS Open Bio, 2014, v. 4, p. 755, doi. 10.1016/j.fob.2014.08.003
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- Article