Works about PROINSULIN

Results: 795

Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action.

Published in:

PLoS Biology, 2003, v. 1, n. 1, p. 41

By:

Barroso, Ines;
Luan, Jian'an;
Middelberg, Rita P. S.;
Harding, Anne-Helen;
Franks, Paul W.;
Jakes, Rupert W.;
Clayton, David;
Schafer, Alan J.;
O'Rahilly, Stephen;
Wareham, Nicholas J.

Publication type:

Article

Growth and nutrient utilisation of blackspot seabream ( Pagellus bogaraveo) under different feeding regimes.

Published in:

Fish Physiology & Biochemistry, 2010, v. 36, n. 4, p. 1113, doi. 10.1007/s10695-010-9389-4

By:

Figueiredo-Silva, A. Cláudia;
Corraze, Geneviève;
Sanchez-Gurmaches, Joan;
Gutiérrez, Joaquim;
Valente, Luísa M. P.

Publication type:

Article

Expression and characterization of human proinsulin fused to thioredoxin in Escherichia coli.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 94, n. 6, p. 1565, doi. 10.1007/s00253-011-3721-5

By:

Trabucchi, Aldana;
Guerra, Luciano;
Faccinetti, Natalia;
Iacono, Ruben;
Poskus, Edgardo;
Valdez, Silvina

Publication type:

Article

Therapeutic insulins and their large-scale manufacture.

Published in:

Applied Microbiology & Biotechnology, 2005, v. 67, n. 2, p. 151, doi. 10.1007/s00253-004-1809-x

By:

Walsh, Gary

Publication type:

Article

Genetic system constructed to overproduce and secrete proinsulin in Bacillus subtilis.

Published in:

Applied Microbiology & Biotechnology, 2003, v. 62, n. 4, p. 369, doi. 10.1007/s00253-003-1289-4

By:

Olmos-Soto, J.;
Contreras-Flores, R.

Publication type:

Article

Circulating Adiponectin Levels and Expression of Adiponectin Receptors in Relation to Lung Cancer: Two Case-Control Studies.

Published in:

Oncology, 2007, v. 73, n. 3/4, p. 261, doi. 10.1159/000127424

By:

Petridou, Eleni T.;
Mitsiades, Nicholas;
Gialamas, Spyros;
Angelopoulos, Miltiadis;
Skalkidou, Alkistis;
Dessypris, Nick;
Hsi, Alex;
Lazaris, Nikolaos;
Polyzos, Aristidis;
Syrigos, Constantinos;
Brennan, Aoife M.;
Tseleni-Balafouta, Sofia;
Mantzoros, Christos S.

Publication type:

Article

Connective Tissue Growth Factor and Insulin-Like Growth Factor 2 Show Upregulation in Early Growth Plate Radiorecovery Response following Irradiation.

Published in:

Cells Tissues Organs, 2007, v. 186, n. 3, p. 192, doi. 10.1159/000105673

By:

Yan Wang;
Mingliang Zhang;
Middleton, Frank A.;
Horton, Jason A.;
Pritchard, Meredith;
Spadaro, Joseph A.;
Farnum, Cornelia E.;
Damron, Timothy A.

Publication type:

Article

The Medi-RIVAGE study (Mediterranean Diet, Cardiovascular Risks and Gene Polymorphisms): rationale, recruitment, design, dietary intervention and baseline characteristics of participants.

Published in:

Public Health Nutrition, 2004, v. 7, n. 4, p. 531, doi. 10.1079/PHN2003547

By:

S Vincent;
M Gerber;
MC Bernard;
C Defoort;
A Loundou;
H Portugal;
R Planells;
I Juhan-Vague;
P Charpiot;
P Grolier;
MJ Amiot-Carlin;
P Vague;
D Lairon

Publication type:

Article

The Impact of Transgenic IGF-IR Overexpression on Mammary Development and Tumorigenesis.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2008, v. 13, n. 4, p. 407, doi. 10.1007/s10911-008-9097-1

By:

Robert Jones;
Roger Moorehead

Publication type:

Article

Characterization and optimization of two-chain folding pathways of insulin via native chain assembly.

Published in:

Communications Chemistry, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42004-018-0024-0

By:

Arai, Kenta;
Takei, Toshiki;
Shinozaki, Reina;
Noguchi, Masato;
Fujisawa, Shouta;
Katayama, Hidekazu;
Moroder, Luis;
Ando, Setsuko;
Okumura, Masaki;
Inaba, Kenji;
Hojo, Hironobu;
Iwaoka, Michio

Publication type:

Article

Preparation, characterization, and in vivo evaluation of insulin-loaded PLA–PEG microspheres for controlled parenteral drug delivery.

Published in:

Drug Development & Industrial Pharmacy, 2009, v. 35, n. 11, p. 1364, doi. 10.3109/03639040902939213

By:

Sheshala, Ravi;
Peh, Kok Khiang;
Darwis, Yusrida

Publication type:

Article

The preparation and application of pulmonary surfactant nanoparticles as absorption enhancers in insulin dry powder delivery.

Published in:

Drug Development & Industrial Pharmacy, 2009, v. 35, n. 9, p. 1059, doi. 10.1080/03639040902769628

By:

Zhang, Yong;
Zhu, Jiabi;
Tang, Yue;
Chen, Xijing;
Yang, Yan

Publication type:

Article

Formulation of Insulin-Loaded Polymeric Nanoparticles Using Response Surface Methodology.

Published in:

Drug Development & Industrial Pharmacy, 2005, v. 31, n. 2, p. 179, doi. 10.1081/DDC-200047802

By:

Attivi, D.;
Wehrle, P.;
Ubrich, N.;
Damge, C.;
Hoffman, M.;
Maincent, P.

Publication type:

Article

The Autoantigenic Proinsulin B-Chain Peptide B11-23 Synergises with the 70 kDa Heat Shock Protein DnaK in Macrophage Stimulation.

Published in:

Journal of Diabetes Research, 2018, p. 1, doi. 10.1155/2018/4834673

By:

Blasius, Elias;
Gülden, Elke;
Kolb, Hubert;
Habich, Christiane;
Burkart, Volker

Publication type:

Article

Proinsulin Promotes Self-Renewal of a Hematopoietic Progenitor Cell Line In Vitro.

Published in:

Journal of Diabetes Research, 2017, p. 1, doi. 10.1155/2017/5649191

By:

Han, Yuewen;
Liu, Tingting;
Zou, Yunding;
Ji, Ling;
Li, Yuanyuan;
Li, Jing;
Wang, Jing;
Chen, Guopin;
Chen, Jieping;
Chen, Liang;
Ye, Zhijia

Publication type:

Article

Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus – a new surrogate measure of non-progression?

Published in:

Pediatric Diabetes, 2004, v. 5, n. 2, p. 72, doi. 10.1111/j.1399-543X.2004.00047.x

By:

Schatz, Desmond;
Cuthbertson, David;
Atkinson, Mark;
Salzler, Michael Clare;
Winter, William;
Muir, Andrew;
Silverstein, Janet;
Cook, Roberta;
Maclaren, Noel;
Jin-Xiong She;
Greenbaum, Carla;
Krischer, Jeffrey

Publication type:

Article

Computational insights into the allosteric behavior of mini proinsulin driven by C peptide mobility.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-92799-8

By:

Ayan, Esra

Publication type:

Article

Production of recombinant human proinsulin in the milk of transgenic mice.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06465

By:

Xi Qian;
Kraft, Jana;
Yingdong Ni;
Feng-Qi Zhao

Publication type:

Article

Acute Pulmonary Edema Due to Rosiglitazone Use in a Patient With Diabetes Mellitus.

Published in:

Journal of Intensive Care Medicine, 2006, v. 21, n. 1, p. 47, doi. 10.1177/0885066605283385

By:

çEkmen, Nedim;
Cesur, Mustafa;
Çetinbas, Riza;
Bedel, Paşa;
Erdemli, Özcan

Publication type:

Article

Type 2 diabetes, glycaemic traits, structural brain capacity and cognitive function: A Mendelian randomization analysis.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, n. 9, p. 3618, doi. 10.1111/dom.15702

By:

Luo, Manjun;
Sun, Mengting;
Wang, Tingting;
Wei, Jianhui;
Ruan, Xiaorui;
Chen, Kebin;
Ou, Jun;
Chen, Yige;
Qin, Jiabi

Publication type:

Article

Metformin restores prohormone processing enzymes and normalizes aberrations in secretion of proinsulin and insulin in palmitate‐exposed human islets.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 12, p. 3757, doi. 10.1111/dom.15270

By:

Wen, Quan;
Chowdhury, Azazul Islam;
Aydin, Banu;
Shekha, Mudhir;
Stenlid, Rasmus;
Forslund, Anders;
Bergsten, Peter

Publication type:

Article

Effects of proinsulin misfolding on β‐cell dynamics, differentiation and function in diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2018, v. 20, p. 95, doi. 10.1111/dom.13379

By:

Riahi, Yael;
Israeli, Tal;
Cerasi, Erol;
Leibowitz, Gil

Publication type:

Article

Novel hepato-preferential basal insulin peglispro ( BIL) does not differentially affect insulin sensitivity compared with insulin glargine in patients with type 1 and type 2 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, n. 4, p. 482, doi. 10.1111/dom.12834

By:

Porksen, Niels;
Linnebjerg, Helle;
Garhyan, Parag;
Lam, Eric C. Q.;
Knadler, Mary P.;
Jacober, Scott J.;
Hoevelmann, Ulrike;
Plum‐Moerschel, Leona;
Watkins, Elaine;
Gastaldelli, Amalia;
Heise, Tim

Publication type:

Article

Randomized double-blind clinical trial comparing basal insulin peglispro and insulin glargine, in combination with prandial insulin lispro, in patients with type 2 diabetes: IMAGINE 4.

Published in:

Diabetes, Obesity & Metabolism, 2016, v. 18, n. 11, p. 1072, doi. 10.1111/dom.12696

By:

Blevins, T.;
Pieber, T. R.;
Colón Vega, G.;
Zhang, S.;
Bastyr, E. J.;
Chang, A. M.

Publication type:

Article

Randomized, double-blind clinical trial comparing basal insulin peglispro and insulin glargine, in combination with prandial insulin lispro, in patients with type 1 diabetes: IMAGINE 3.

Published in:

Diabetes, Obesity & Metabolism, 2016, v. 18, n. 11, p. 1081, doi. 10.1111/dom.12698

By:

Bergenstal, R. M.;
Lunt, H.;
Franek, E.;
Travert, F.;
Mou, J.;
Qu, Y.;
Antalis, C. J.;
Hartman, M. L.;
Rosilio, M.;
Jacober, S. J.;
Bastyr, E. J.

Publication type:

Article

Benefits of combination of insulin degludec and liraglutide are independent of baseline glycated haemoglobin level and duration of type 2 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2016, v. 18, n. 1, p. 40, doi. 10.1111/dom.12574

By:

Rodbard, H. W.;
Buse, J. B.;
Woo, V.;
Vilsbøll, T.;
Langbakke, I. H.;
Kvist, K.;
Gough, S. C. L.

Publication type:

Article

Pancreatic β-cell imaging in humans: fiction or option?

Published in:

Diabetes, Obesity & Metabolism, 2016, v. 18, n. 1, p. 6, doi. 10.1111/dom.12544

By:

Laurent, D.;
Vinet, L.;
Lamprianou, S.;
Daval, M.;
Filhoulaud, G.;
Ktorza, A.;
Wang, H.;
Sewing, S.;
Juretschke, H.‐P.;
Glombik, H.;
Meda, P.;
Boisgard, R.;
Nguyen, D. L.;
Stasiuk, G. J.;
Long, N. J.;
Montet, X.;
Hecht, P.;
Kramer, W.;
Rutter, G. A.;
Hecksher‐Sørensen, J.

Publication type:

Article

Effect of vildagliptin compared to glimepiride on postprandial proinsulin processing in the β cell of patients with type 2 diabetes mellitus.

Published in:

Diabetes, Obesity & Metabolism, 2013, v. 15, n. 6, p. 576, doi. 10.1111/dom.12063

By:

Forst, T.;
Dworak, M.;
Berndt‐Zipfel, C.;
Löffler, A.;
Klamp, I.;
Mitry, M.;
Pfützner, A.

Publication type:

Article

Interactions between genetic background, insulin resistance and β-cell function.

Published in:

Diabetes, Obesity & Metabolism, 2012, v. 14, p. 46, doi. 10.1111/j.1463-1326.2012.01650.x

By:

Kahn, S. E.;
Suvag, S.;
Wright, L. A.;
Utzschneider, K. M.

Publication type:

Article

The effect of initial therapy with the fixed-dose combination of sitagliptin and metformin compared with metformin monotherapy in patients with type 2 diabetes mellitus.

Published in:

Diabetes, Obesity & Metabolism, 2011, v. 13, n. 7, p. 644, doi. 10.1111/j.1463-1326.2011.01390.x

By:

Reasner, C.;
Olansky, L.;
Seck, T. L.;
Williams-Herman, D. E.;
Chen, M.;
Terranella, L.;
Johnson-Levonas, A. O.;
Kaufman, K. D.;
Goldstein, B. J.

Publication type:

Article

Beta-cell function is disrupted in patients with systemic lupus erythematosus.

Published in:

Rheumatology, 2021, v. 60, n. 8, p. 3826, doi. 10.1093/rheumatology/keaa874

By:

García-Dorta, Alicia;
Quevedo-Abeledo, Juan Carlos;
Rua-Figueroa, Íñigo;
Vera-González, Antonia M de;
González-Delgado, Alejandra;
Medina-Vega, Lilian;
González-Rivero, Agustín F;
Francisco-Hernández, Felix;
González-Gay, Miguel A;
Ferraz-Amaro, Iván

Publication type:

Article

Decreased diabetes risk over 9 year after 18-month oral L-arginine treatment in middle-aged subjects with impaired glucose tolerance and metabolic syndrome (extension evaluation of L-arginine study).

Published in:

European Journal of Nutrition, 2018, v. 57, n. 8, p. 2805, doi. 10.1007/s00394-017-1548-2

By:

Monti, Lucilla D.;
Galluccio, Elena;
Villa, Valentina;
Fontana, Barbara;
Spadoni, Serena;
Piatti, Pier Marco

Publication type:

Article

Use of Automated Bolus Calculators for Diabetes Management.

Published in:

European Endocrinology, 2013, v. 9, n. 2, p. 92

By:

Schwartz, Frank L.;
Marling, Cynthia R.

Publication type:

Article

Evaluation of the JuniorSTAR Half-unit Insulin Pen in Young People with Type 1 Diabetes - User Perspectives.

Published in:

European Endocrinology, 2013, v. 9, n. 2, p. 82

By:

Klonoff, David;
Nayberg, Irina;
Rabbone, Ivana;
Landgraf, Wolfgang;
Domenger, Catherine;
Danne, Thomas

Publication type:

Article

Etiopathogenesis of Insulin Autoimmunity.

Published in:

Anatomy Research International, 2012, p. 1, doi. 10.1155/2012/457546

By:

Kanatsuna, Norio;
Papadopoulos, George K.;
Moustakas, Antonis K.;
Lenmark, Åke

Publication type:

Article

Insulin lispro low mixture twice daily vs basal insulin glargine once daily and prandial insulin lispro once daily as insulin intensification strategies in patients with type 2 diabetes: Latin American subpopulation analysis of a randomized trial.

Published in:

Diabetology & Metabolic Syndrome, 2016, v. 8, p. 1, doi. 10.1186/s13098-016-0163-3

By:

Rojas, Arturo;
Sposetti, Georgina;
Gross, Jorge L.;
Barbieri, Douglas Eugenio;
Duan, Ran;
Linetzky, Bruno;
De Lana, Janaina Martins;
Stempa, Oded;
Rodriguez, Angel

Publication type:

Article

Hibiscus sabdariffa calyx palliates insulin resistance, hyperglycemia, dyslipidemia and oxidative rout in fructose-induced metabolic syndrome rats.

Published in:

Journal of the Science of Food & Agriculture, 2016, v. 96, n. 5, p. 1522, doi. 10.1002/jsfa.7254

By:

Ajiboye, Taofeek O;
Raji, Hikmat O;
Adeleye, Abdulwasiu O;
Adigun, Nurudeen S;
Giwa, Oluwayemisi B;
Ojewuyi, Oluwayemisi B;
Oladiji, Adenike T

Publication type:

Article

Isolation of <em>C. dubliniensis</em> from insulin-using diabetes mellitus patients.

Published in:

Journal of Oral Pathology & Medicine, 2000, v. 29, n. 2, p. 86, doi. 10.1034/j.1600-0714.2000.290206.x

By:

Willis, A. M.;
Coulter, W. A.;
Sullivan, D. J.;
Coleman, D. C.;
Hayes, J. R.;
Bell, P. M.;
Lamey, P.-J.

Publication type:

Article

ARGININE EFFECTS ON IN VIVO GLUCOSE-INDUCED INSULIN SECRETION IN MICE AND HAMSTERS.

Published in:

Studia Universitatis Vasile Goldis Seria Stiintele Vietii (Life Sciences Series), 2008, v. 18, p. 229

By:

Trandaburu, Ioana;
Mirancea, Dorina;
Simionescu, Mirela;
Trandaburu, Tiberiu

Publication type:

Article

Periodontis Is Associated With Aggravation of Prediabetes in Zucker Fatty Rats.

Published in:

Journal of Periodontology, 2007, v. 78, n. 3, p. 559, doi. 10.1902/jop.2007.060358

By:

Andersen, Carla C. Pontes;
Flyvbjerg, Allan;
Buschard, Karsten;
Holmstrup, Palle

Publication type:

Article

Associations between the intake of dairy fat and calcium and abdominal obesity.

Published in:

International Journal of Obesity & Related Metabolic Disorders, 2004, v. 28, n. 11, p. 1427, doi. 10.1038/sj.ijo.0802769

By:

Rosell, M.;
Johansson, G.;
Berglund, L.;
Vessby, B.;
de Faire, U.;
Hellénius, M.-L.

Publication type:

Article

Overweight and obesity and the burden of disease and disability in elderly men.

Published in:

International Journal of Obesity & Related Metabolic Disorders, 2004, v. 28, n. 11, p. 1374, doi. 10.1038/sj.ijo.0802775

By:

Wannamethee, S. Goya;
Shaper, A.Gerald;
Whincup, P. H.;
Walker, M.

Publication type:

Article

Insulin, islet amyloid polypeptide and C-peptide interactions evaluated by mass spectrometric analysis.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2014, v. 28, n. 2, p. 178, doi. 10.1002/rcm.6772

By:

Landreh, Michael;
Alvelius, Gunvor;
Johansson, Jan;
Jörnvall, Hans

Publication type:

Article

Insulin Null β-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression.

Published in:

Endocrinology, 2022, v. 163, n. 6, p. 1, doi. 10.1210/endocr/bqac051

By:

Ramzy, Adam;
Edeer, Nazde;
Baker, Robert K;
O'Dwyer, Shannon;
Mojibian, Majid;
Verchere, C Bruce;
Kieffer, Timothy J

Publication type:

Article

Factors affecting costs and utilization of type 2 diabetes healthcare: a cross-sectional survey among 15 hospitals in urban China.

Published in:

BMC Health Services Research, 2010, v. 10, p. 244, doi. 10.1186/1472-6963-10-244

By:

Weibing Wang;
Chaowei Fu;
Haijing Zhuo;
Jianfeng Luo;
Biao Xu

Publication type:

Article

Associations of age with serum insulin, proinsulin and the proinsulin-to-insulin ratio: a crosssectional study.

Published in:

BMC Endocrine Disorders, 2010, v. 10, p. 21, doi. 10.1186/1472-6823-10-21

By:

Bryhni, Bente;
Arnesen, Egil;
Jenssen, Trond G.

Publication type:

Article

The ENPP1 K121Q polymorphism is not associated with type 2 diabetes and related metabolic traits in an Iranian population.

Published in:

Molecular & Cellular Biochemistry, 2011, v. 350, n. 1/2, p. 113, doi. 10.1007/s11010-010-0687-z

By:

Saberi, Hamzeh;
Mohammadtaghvaei, Narges;
Gulkho, Shekufeh;
Bakhtiyari, Salar;
Mohammadi, Mohammad;
Hanachi, Parichehr;
Gerayesh-nejad, Siavash;
Zargari, Mehryar;
Ataei, Farangis;
Parvaneh, Leila;
Larijani, Bagher;
Meshkani, Reza

Publication type:

Article

Nutrigenomic basis of beneficial effects of chromium(III) on obesity and diabetes.

Published in:

Molecular & Cellular Biochemistry, 2008, v. 317, n. 1/2, p. 1, doi. 10.1007/s11010-008-9744-2

By:

Francis Lau;
Manashi Bagchi;
Chandan Sen

Publication type:

Article

Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats.

Published in:

Molecular & Cellular Biochemistry, 2007, v. 306, n. 1/2, p. 133, doi. 10.1007/s11010-007-9563-x

By:

Xuming Jia;
Lingyun Wu

Publication type:

Article

Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes.

Published in:

Molecular & Cellular Biochemistry, 2007, v. 297, n. 1/2, p. 171, doi. 10.1007/s11010-006-9344-y

By:

Paul Brown;
Simone Badal;
Seian Morrison;
Dalip Ragoobirsingh

Publication type:

Article