Works matching DE "PROGRANULIN"
Results: 366
Early-Phase Trial Launches of VES001 for Gene-Related Frontotemporal Dementia.
- Published in:
- Patient Care (Online), 2025, p. 7
- Publication type:
- Article
Progranulin deficiency results in sex-dependent alterations in microglia in response to demyelination.
- Published in:
- Acta Neuropathologica, 2023, v. 146, n. 1, p. 97, doi. 10.1007/s00401-023-02578-w
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- Publication type:
- Article
The lysosomal function of progranulin, a guardian against neurodegeneration.
- Published in:
- Acta Neuropathologica, 2018, v. 136, n. 1, p. 1, doi. 10.1007/s00401-018-1861-8
- By:
- Publication type:
- Article
Regulation of cathepsin D activity by the FTLD protein progranulin.
- Published in:
- 2017
- By:
- Publication type:
- Letter
Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.
- Published in:
- Acta Neuropathologica, 2017, v. 133, n. 5, p. 785, doi. 10.1007/s00401-017-1668-z
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- Publication type:
- Article
Serum progranulin level is a novel tool for monitoring disease activity of dermatomyositis with antimelanoma differentiation‐associated protein 5 antibodies.
- Published in:
- Journal of Cutaneous Immunology & Allergy, 2021, v. 4, n. 3, p. 50, doi. 10.1002/cia2.12160
- By:
- Publication type:
- Article
血清 PGRN、SFRP1、CCL26 与支气管哮喘急性发作期患者肺功能 和气道炎症的相关性研究.
- Published in:
- Progress in Modern Biomedicine, 2023, v. 23, n. 15, p. 2873, doi. 10.13241/j.cnki.pmb.2023.15.014
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- Publication type:
- Article
血清 APN、PGRN 联合检测对脓毒症患儿疾病的预测价值 及与其预后的相关性分析.
- Published in:
- Progress in Modern Biomedicine, 2022, v. 22, n. 8, p. 1596, doi. 10.13241/j.cnki.pmb.2022.08.041
- By:
- Publication type:
- Article
Increased circulating progranulin is not sufficient to induce cardiac dysfunction or supraventricular arrhythmia.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47311-5
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- Publication type:
- Article
Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40347-7
- By:
- Publication type:
- Article
Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-40347-7
- By:
- Publication type:
- Article
Adipokines, Hepatokines and Myokines: Focus on Their Role and Molecular Mechanisms in Adipose Tissue Inflammation.
- Published in:
- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.873699
- By:
- Publication type:
- Article
Progranulin and Its Receptor Predict Kidney Function Decline in Patients With Type 2 Diabetes.
- Published in:
- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.849457
- By:
- Publication type:
- Article
Progranulin Mutations Affects Brain Oscillatory Activity in Fronto-Temporal Dementia.
- Published in:
- Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00035
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- Publication type:
- Article
Frontotemporal Lobar Degeneration and MicroRNAs.
- Published in:
- Frontiers in Aging Neuroscience, 2016, p. 10, doi. 10.3389/fnagi.2016.00017
- By:
- Publication type:
- Article
Commentary: Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice.
- Published in:
- 2016
- By:
- Publication type:
- Opinion
Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Longitudinal Neuropsychological Study of Presymptomatic C.709-1G > A Progranulin Mutation Carriers.
- Published in:
- Journal of the International Neuropsychological Society, 2019, v. 25, n. 1, p. 39, doi. 10.1017/S1355617718000735
- By:
- Publication type:
- Article
Early Neuropsychological Characteristics of Progranulin Mutation Carriers.
- Published in:
- Journal of the International Neuropsychological Society, 2014, v. 20, n. 7, p. 694, doi. 10.1017/S1355617714000551
- By:
- Publication type:
- Article
Neuropsychological Features of Asymptomatic c.709-1G>A Progranulin Mutation Carriers.
- Published in:
- Journal of the International Neuropsychological Society, 2012, v. 18, n. 6, p. 1086, doi. 10.1017/S1355617712000823
- By:
- Publication type:
- Article
Clinicopathological characteristics and outcomes of gastrointestinal stromal tumors with high progranulin expression.
- Published in:
- PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0245153
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- Publication type:
- Article
Serum progranulin levels are associated with frailty in middle-aged individuals.
- Published in:
- PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0238877
- By:
- Publication type:
- Article
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0281-5
- By:
- Publication type:
- Article
Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0264-6
- By:
- Publication type:
- Article
Lysosomal processing of progranulin.
- Published in:
- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0205-9
- By:
- Publication type:
- Article
The lysosomal protein cathepsin L is a progranulin protease.
- Published in:
- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0196-6
- By:
- Publication type:
- Article
Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0132-1
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- Publication type:
- Article
Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0114-3
- By:
- Publication type:
- Article
Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0102-7
- By:
- Publication type:
- Article
Progranulin Is Associated with Disease Activity in Patients with Rheumatoid Arthritis.
- Published in:
- Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/740357
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- Publication type:
- Article
Plasma Progranulin Concentrations Are Increased in Patients with Type 2 Diabetes and Obesity and Correlated with Insulin Resistance.
- Published in:
- Mediators of Inflammation, 2013, v. 2013, p. 1, doi. 10.1155/2013/360190
- By:
- Publication type:
- Article
Prevention of LPS-Induced Acute Lung Injury in Mice by Progranulin.
- Published in:
- Mediators of Inflammation, 2012, v. 2012, p. 1, doi. 10.1155/2012/540794
- By:
- Publication type:
- Article
Single intracerebroventricular progranulin injection adversely affects the blood-brain barrier in experimental traumatic brain injury.
- Published in:
- Journal of Neurochemistry, 2021, v. 158, n. 2, p. 342, doi. 10.1111/jnc.15375
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- Publication type:
- Article
Progranulin in neurodegenerative dementia.
- Published in:
- Journal of Neurochemistry, 2021, v. 158, n. 2, p. 119, doi. 10.1111/jnc.15378
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- Publication type:
- Article
Progranulin in neurodegenerative dementia.
- Published in:
- Journal of Neurochemistry, 2021, v. 158, n. 1, p. 119, doi. 10.1111/jnc.15378
- By:
- Publication type:
- Article
Single intracerebroventricular progranulin injection adversely affects the blood–brain barrier in experimental traumatic brain injury.
- Published in:
- Journal of Neurochemistry, 2021, v. 158, n. 1, p. 342, doi. 10.1111/jnc.15375
- By:
- Publication type:
- Article
The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C.
- Published in:
- Journal of Neurochemistry, 2017, v. 143, n. 2, p. 236, doi. 10.1111/jnc.14110
- By:
- Publication type:
- Article
Another piece in the progranulin puzzle: special binding between progranulin and prosaposin creates additional lysosomal access.
- Published in:
- 2017
- By:
- Publication type:
- Editorial
Genetics of FTLD: overview and what else we can expect from genetic studies.
- Published in:
- Journal of Neurochemistry, 2016, v. 138, p. 32, doi. 10.1111/jnc.13622
- By:
- Publication type:
- Article
Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stress.
- Published in:
- Lipids in Health & Disease, 2017, v. 16, p. 1, doi. 10.1186/s12944-017-0425-6
- By:
- Publication type:
- Article
Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Progranulin (PGRN) as a regulator of inflammation and a critical factor in the immunopathogenesis of cardiovascular diseases.
- Published in:
- 2023
- By:
- Publication type:
- Literature Review
Progranulin as a predictive factor of response to chemotherapy in advanced biliary tract carcinoma.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Acute-phase proteins in prediction of preeclampsia in patients with abnormal midtrimester uterine Doppler velocimetry.
- Published in:
- Archives of Gynecology & Obstetrics, 2016, v. 294, n. 6, p. 1151, doi. 10.1007/s00404-016-4138-2
- By:
- Publication type:
- Article
Are progranulin levels associated with polycystic ovary syndrome and its possible metabolic effects in adolescents and young women?
- Published in:
- 2016
- By:
- Publication type:
- journal article
Progranulin shows cytoprotective effects on trophoblast cells in vitro but does not antagonize TNF-α-induced apoptosis.
- Published in:
- Archives of Gynecology & Obstetrics, 2014, v. 290, n. 5, p. 867, doi. 10.1007/s00404-014-3296-3
- By:
- Publication type:
- Article
High Serum Progranulin Levels in COVID-19 Patients: A Pilot Study.
- Published in:
- Biochemistry (00062979), 2022, v. 87, n. 3, p. 207, doi. 10.1134/S0006297922030026
- By:
- Publication type:
- Article
Phase 1 study of latozinemab in progranulin‐associated frontotemporal dementia.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2024, v. 10, n. 1, p. 1, doi. 10.1002/trc2.12452
- By:
- Publication type:
- Article
Progranulin gene ( GRN) promoter methylation is increased in patients with sporadic frontotemporal lobar degeneration.
- Published in:
- Neurological Sciences, 2013, v. 34, n. 6, p. 899, doi. 10.1007/s10072-012-1151-5
- By:
- Publication type:
- Article
Prevalence of frontotemporal lobar degeneration in an isolated population: the Vallecamonica study.
- Published in:
- Neurological Sciences, 2012, v. 33, n. 4, p. 899, doi. 10.1007/s10072-011-0865-0
- By:
- Publication type:
- Article