Works matching DE "PREGNANOLONE"

Results: 176

Interaction Between Allopregnanolone and Amiloride Binding Sites on the GABAA Receptor.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2453, doi. 10.1007/s12013-024-01654-6

By:

Bukanova, Julia V.;
Kondratenko, Rodion V.;
Solntseva, Elena I.

Publication type:

Article

Non-clinical studies of progesterone.

Published in:

2018

By:

Sitruk-Ware, R.

Publication type:

journal article

The history of natural progesterone, the never-ending story.

Published in:

2018

By:

Piette, P.

Publication type:

journal article

Open-label, proof-of-concept study of brexanolone in the treatment of severe postpartum depression.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2017, v. 32, n. 2, p. n/a, doi. 10.1002/hup.2576

By:

Kanes, Stephen J.;
Colquhoun, Helen;
Doherty, James;
Raines, Shane;
Hoffmann, Ethan;
Rubinow, David R.;
Meltzer‐Brody, Samantha

Publication type:

Article

Selective Effect of Allopregnanolone on Corticoliberin-Induced Anxiety.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 156, n. 6, p. 722, doi. 10.1007/s10517-014-2433-0

By:

Semenova, O.;
Rakitskaya, V.

Publication type:

Article

A Nested Case-Control Study of Allopregnanolone and Preterm Birth in the Healthy Start Cohort.

Published in:

Journal of the Endocrine Society, 2023, v. 7, n. 2, p. 1, doi. 10.1210/jendso/bvac179

By:

MAYNE, Gabriella B;
DeWITT, Peter E;
RINGHAM, Brandy;
WARRENER, Anna G;
CHRISTIANS, Uwe;
DABELEA, Dana;
HURT, K Joseph

Publication type:

Article

Local effect of allopregnanolone in rat ovarian steroidogenesis, follicular and corpora lutea development.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-57102-1

By:

Cáceres, Antonella Rosario Ramona;
Cardone, Daniela Alejandra;
Sanhueza, María de los Ángeles;
Bosch, Ignacio Manuel;
Cuello-Carrión, Fernando Darío;
Rodriguez, Graciela Beatriz;
Scotti, Leopoldina;
Parborell, Fernanda;
Halperin, Julia;
Laconi, Myriam Raquel

Publication type:

Article

The Role of Allopregnanolone in Pregnancy in Predicting Postpartum Anxiety Symptoms.

Published in:

Frontiers in Psychology, 2019, p. 1, doi. 10.3389/fpsyg.2019.01033

By:

Osborne, Lauren M.;
Betz, Joshua F.;
Yenokyan, Gayane;
Standeven, Lindsay R.;
Payne, Jennifer L.

Publication type:

Article

Acute, but not repeated, cocaine exposure alters allopregnanolone levels in the midbrain of male and female rats.

Published in:

Psychopharmacology, 2024, v. 241, n. 5, p. 1011, doi. 10.1007/s00213-024-06534-8

By:

McFarland, Minna H.;
Machado, Meira M. F.;
Sansbury, Griffin M.;
Musselman, Kate C.;
Boero, Giorgia;
O'Buckley, Todd K.;
Carr, Crystal C.;
Morrow, A. Leslie;
Robinson, Donita L.

Publication type:

Article

Preclinical and clinical pharmacology of brexanolone (allopregnanolone) for postpartum depression: a landmark journey from concept to clinic in neurosteroid replacement therapy.

Published in:

Psychopharmacology, 2023, v. 240, n. 9, p. 1841, doi. 10.1007/s00213-023-06427-2

By:

Reddy, Doodipala Samba;
Mbilinyi, Robert H.;
Estes, Emily

Publication type:

Article

Prefrontal allopregnanolone synergizes with D1 receptor activation to disrupt sensorimotor gating in male Sprague-Dawley rats.

Published in:

Psychopharmacology, 2023, v. 240, n. 6, p. 1359, doi. 10.1007/s00213-023-06375-x

By:

Frau, Roberto;
Traccis, Francesco;
Concas, Luca;
Cadeddu, Roberto;
Mosher, Laura J;
Nordkild, Peter;
Gaikwad, Nilesh W;
Bortolato, Marco

Publication type:

Article

GR3027 reversal of neurosteroid-induced, GABA-A receptor-mediated inhibition of human brain function: an allopregnanolone challenge study.

Published in:

Psychopharmacology, 2018, v. 235, n. 5, p. 1533, doi. 10.1007/s00213-018-4864-1

By:

Johansson, Maja;
Månsson, Maria;
Lins, Lars-Eric;
Scharschmidt, Bruce;
Doverskog, Magnus;
Bäckström, Torbjörn

Publication type:

Article

Juvenile social isolation affects maternal care in rats: involvement of allopregnanolone.

Published in:

Psychopharmacology, 2017, v. 234, n. 17, p. 2587, doi. 10.1007/s00213-017-4661-2

By:

Pisu, Maria;
Boero, Giorgia;
Biggio, Francesca;
Garau, Anna;
Corda, Daniela;
Congiu, Mauro;
Concas, Alessandra;
Porcu, Patrizia;
Serra, Mariangela

Publication type:

Article

A randomized controlled trial of ganaxolone in posttraumatic stress disorder.

Published in:

Psychopharmacology, 2017, v. 234, n. 15, p. 2245, doi. 10.1007/s00213-017-4649-y

By:

Rasmusson, Ann;
Marx, Christine;
Jain, Sonia;
Farfel, Gail;
Tsai, Julia;
Sun, Xiaoying;
Geracioti, Thomas;
Hamner, Mark;
Lohr, James;
Rosse, Richard;
Summerall, Lanier;
Naylor, Jennifer;
Cusin, Cristine;
Lang, Ariel;
Raman, Rema;
Stein, Murray

Publication type:

Article

Changes in stress-stimulated allopregnanolone levels induced by neonatal estradiol treatment are associated with enhanced dopamine release in adult female rats: reversal by progesterone administration.

Published in:

Psychopharmacology, 2017, v. 234, n. 5, p. 749, doi. 10.1007/s00213-016-4511-7

By:

Porcu, Patrizia;
Lallai, Valeria;
Locci, Andrea;
Catzeddu, Sandro;
Serra, Valeria;
Pisu, Maria;
Serra, Mariangela;
Dazzi, Laura;
Concas, Alessandra

Publication type:

Article

Women with premenstrual dysphoric disorder have altered sensitivity to allopregnanolone over the menstrual cycle compared to controls-a pilot study.

Published in:

Psychopharmacology, 2016, v. 233, n. 11, p. 2109, doi. 10.1007/s00213-016-4258-1

By:

Timby, Erika;
Bäckström, Torbjörn;
Nyberg, Sigrid;
Stenlund, Hans;
Wihlbäck, Anna-Carin;
Bixo, Marie

Publication type:

Article

Effect of nucleus accumbens shell infusions of ganaxolone or gaboxadol on ethanol consumption in mice.

Published in:

Psychopharmacology, 2015, v. 232, n. 8, p. 1415, doi. 10.1007/s00213-014-3777-x

By:

Ramaker, Marcia;
Strong-Kaufman, Moriah;
Ford, Matthew;
Phillips, Tamara;
Finn, Deborah

Publication type:

Article

Differential responses of two related neurosteroids to methylphenidate based on ADHD subtype and the presence of depressive symptomatology.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3635, doi. 10.1007/s00213-014-3514-5

By:

Molina-Carballo, Antonio;
Justicia-Martínez, Fuensanta;
Moreno-Madrid, Francisco;
Cubero-Millán, Isabel;
Machado-Casas, Irene;
Moreno-García, Laura;
León, Josefa;
Luna-del-Castillo, Juan-de-Dios;
Uberos, José;
Muñoz-Hoyos, Antonio

Publication type:

Article

Effects of inhibitory GABA-active neurosteroids on cocaine seeking and cocaine taking in rats.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3391, doi. 10.1007/s00213-013-3404-2

By:

Schmoutz, Christopher;
Runyon, Scott;
Goeders, Nicholas

Publication type:

Article

The role of ovarian hormone-derived neurosteroids on the regulation of GABA receptors in affective disorders.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3333, doi. 10.1007/s00213-013-3423-z

By:

MacKenzie, Georgina;
Maguire, Jamie

Publication type:

Article

Neuroprotection by the synthetic neurosteroid enantiomers ent-PREGS and ent-DHEAS against Aβ peptide-induced toxicity in vitro and in vivo in mice.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3293, doi. 10.1007/s00213-014-3435-3

By:

El Bitar, Fadia;
Meunier, Johann;
Villard, Vanessa;
Alméras, Marion;
Krishnan, Kathiresan;
Covey, Douglas;
Maurice, Tangui;
Akwa, Yvette

Publication type:

Article

Allopregnanolone modulation of HPA axis function in the adult rat.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3437, doi. 10.1007/s00213-014-3521-6

By:

Biggio, Giovanni;
Pisu, Maria;
Biggio, Francesca;
Serra, Mariangela

Publication type:

Article

Characterization of neurosteroid effects on hyperpolarizing current at α4β2δ GABA receptors.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3525, doi. 10.1007/s00213-014-3538-x

By:

Gong, Qi;
Smith, Sheryl

Publication type:

Article

Decreased allopregnanolone induced by hormonal contraceptives is associated with a reduction in social behavior and sexual motivation in female rats.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3351, doi. 10.1007/s00213-014-3539-9

By:

Santoru, Francesca;
Berretti, Roberta;
Locci, Andrea;
Porcu, Patrizia;
Concas, Alessandra

Publication type:

Article

Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J mice.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3281, doi. 10.1007/s00213-014-3552-z

By:

Maldonado-Devincci, Antoniette;
Beattie, Matthew;
Morrow, Danielle;
McKinley, Raechel;
Cook, Jason;
O'Buckley, Todd;
Morrow, A.

Publication type:

Article

Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3257, doi. 10.1007/s00213-014-3564-8

By:

Porcu, Patrizia;
Morrow, A.

Publication type:

Article

5α-reductase type I expression is downregulated in the prefrontal cortex/Brodmann's area 9 (BA9) of depressed patients.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3569, doi. 10.1007/s00213-014-3567-5

By:

Agis-Balboa, Roberto;
Guidotti, Alessandro;
Pinna, Graziano

Publication type:

Article

Neurosteroid, GABAergic and hypothalamic pituitary adrenal (HPA) axis regulation: what is the current state of knowledge in humans?

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3619, doi. 10.1007/s00213-014-3572-8

By:

Crowley, Shannon;
Girdler, Susan

Publication type:

Article

Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3503, doi. 10.1007/s00213-014-3588-0

By:

Ayoola, Christine;
Hwang, Sung;
Hong, Sung;
Rose, Kirstin;
Boyd, Christopher;
Bozic, Neda;
Park, Ji-Yong;
Osuru, Hari;
DiGruccio, Michael;
Covey, Douglas;
Jevtovic-Todorovic, Vesna;
Todorovic, Slobodan

Publication type:

Article

Effects of the neuroactive steroid allopregnanolone on intracranial self-stimulation in C57BL/6J Mice.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3415, doi. 10.1007/s00213-014-3600-8

By:

Fish, Eric;
Whitman, Buddy;
DiBerto, Jeff;
Robinson, J.;
Morrow, A.;
Malanga, C.

Publication type:

Article

Discriminative stimulus effects of pregnanolone in rhesus monkeys.

Published in:

Psychopharmacology, 2014, v. 231, n. 1, p. 181, doi. 10.1007/s00213-013-3218-2

By:

Gerak, Lisa;
France, Charles

Publication type:

Article

Neurosteroid interactions with synaptic and extrasynaptic GABA receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.

Published in:

Psychopharmacology, 2013, v. 230, n. 2, p. 151, doi. 10.1007/s00213-013-3276-5

By:

Carver, Chase;
Reddy, Doodipala

Publication type:

Article

Discriminative stimulus effects of pregnanolone in rats: role of training dose in determining mechanism of action.

Published in:

Psychopharmacology, 2012, v. 223, n. 2, p. 139, doi. 10.1007/s00213-012-2701-5

By:

Eppolito, Amy;
Bai, Xiang;
Gerak, Lisa

Publication type:

Article

Structural insights into opposing actions of neurosteroids on GABAA receptors.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40800-1

By:

Legesse, Dagimhiwat H.;
Fan, Chen;
Teng, Jinfeng;
Zhuang, Yuxuan;
Howard, Rebecca J.;
Noviello, Colleen M.;
Lindahl, Erik;
Hibbs, Ryan E.

Publication type:

Article

Neurosteroids mediate and modulate the effects of pro-inflammatory stimulation and toll-like receptors on hippocampal plasticity and learning.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0304481

By:

Izumi, Yukitoshi;
O'Dell, Kazuko A.;
Cashikar, Anil G.;
Paul, Steven M.;
Covey, Douglas F.;
Mennerick, Steven J.;
Zorumski, Charles F.

Publication type:

Article

Null Mutation of 5α-Reductase Type I Gene Alters Ethanol Consumption Patterns in a Sex-Dependent Manner.

Published in:

Behavior Genetics, 2015, v. 45, n. 3, p. 341, doi. 10.1007/s10519-014-9694-2

By:

Ford, Matthew;
Nickel, Jeffrey;
Kaufman, Moriah;
Finn, Deborah

Publication type:

Article

Increased Superoxide Dismutase 2 by Allopregnanolone Ameliorates ROS-Mediated Neuronal Death in Mice with Pilocarpine-Induced Status Epilepticus.

Published in:

Neurochemical Research, 2018, v. 43, n. 7, p. 1464, doi. 10.1007/s11064-018-2561-4

By:

Cho, Inja;
Kim, Won-Joo;
Kim, Hyun-Woo;
Heo, Kyoung;
Lee, Byung In;
Cho, Yang-Je

Publication type:

Article

Brexanolone as adjunctive therapy in super-refractory status epilepticus.

Published in:

2017

By:

Rosenthal, Eric S.;
Claassen, Jan;
Wainwright, Mark S.;
Husain, Aatif M.;
Vaitkevicius, Henrikas;
Raines, Shane;
Hoffmann, Ethan;
Colquhoun, Helen;
Doherty, James J.;
Kanes, Stephen J.

Publication type:

journal article

Place of neurosteroids in the treatment of status epilepticus.

Published in:

Epilepsia (Series 4), 2018, v. 59, n. 2, p. 216, doi. 10.1111/epi.14481

By:

Rossetti, Andrea O.

Publication type:

Article

Intramuscular allopregnanolone and ganaxolone in a mouse model of treatment‐resistant status epilepticus.

Published in:

Epilepsia (Series 4), 2018, v. 59, n. 2, p. 220, doi. 10.1111/epi.13999

By:

Zolkowska, Dorota;
Wu, Chun‐Yi;
Rogawski, Michael A.

Publication type:

Article

Rescue therapies for seizure emergencies: New modes of administration.

Published in:

Epilepsia (Series 4), 2018, v. 59, n. 2, p. 207, doi. 10.1111/epi.14479

By:

Maglalang, Patricia D.;
Rautiola, Davin;
Siegel, Ronald A.;
Fine, Jared M.;
Hanson, Leah R.;
Coles, Lisa D.;
Cloyd, James C.

Publication type:

Article

Reduced steroidogenesis in patients with PCDH19-female limited epilepsy.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 6, p. e91, doi. 10.1111/epi.13772

By:

Trivisano, Marina;
Lucchi, Chiara;
Rustichelli, Cecilia;
Terracciano, Alessandra;
Cusmai, Raffaella;
Ubertini, Grazia Maria;
Giannone, Germana;
Bertini, Enrico Silvio;
Vigevano, Federico;
Gecz, Jozef;
Biagini, Giuseppe;
Specchio, Nicola

Publication type:

Article

Decreased allopregnanolone levels in cerebrospinal fluid obtained during status epilepticus.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 2, p. e16, doi. 10.1111/epi.13625

By:

Meletti, Stefano;
Lucchi, Chiara;
Monti, Giulia;
Giovannini, Giada;
Bedin, Roberta;
Trenti, Tommaso;
Rustichelli, Cecilia;
Biagini, Giuseppe

Publication type:

Article

Neuroactive steroids for the treatment of status epilepticus.

Published in:

Epilepsia (Series 4), 2013, v. 54, p. 93, doi. 10.1111/epi.12289

By:

Rogawski, Michael A.;
Loya, Carlos M.;
Reddy, Kiran;
Zolkowska, Dorota;
Lossin, Christoph

Publication type:

Article

Development and validation of an LC-MS/MS assay for the quantification of allopregnanolone and its progesterone-derived isomers, precursors, and cortisol/cortisone in pregnancy.

Published in:

Analytical & Bioanalytical Chemistry, 2021, v. 413, n. 21, p. 5427, doi. 10.1007/s00216-021-03523-0

By:

Mayne, G.;
De Bloois, E.;
Dabelea, D.;
Christians, U.

Publication type:

Article

The Role of Allopregnanolone Levels in Traumatic Brain Injury in Children and Adults and the Correlation of Its Levels with Computerized Tomography Images of the Brain.

Published in:

Indian Journal of Neurosurgery, 2020, v. 9, n. 1, p. 24, doi. 10.1055/s-0040-1701323

By:

Coskun, Göker;
Beceren, Nesrin Gökben;
Bedel, Cihan

Publication type:

Article

Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model.

Published in:

Korean Journal of Pain, 2018, v. 31, n. 1, p. 10, doi. 10.3344/kjp.2018.31.1.10

By:

Masahide Fujita;
Taeko Fukuda;
Yasuhiro Sato;
Toshifumi Takasusuki;
Makoto Tanaka

Publication type:

Article

Allopregnanolone: A neurosteroid for managing acute and chronic pain conditions.

Published in:

Saudi Journal of Anaesthesia, 2019, v. 13, n. 3, p. 264, doi. 10.4103/sja.SJA_830_18

By:

Nair, Abhijit;
Diwan, Sandeep

Publication type:

Article

Social Isolation in Early versus Late Adolescent Mice Is Associated with Persistent Behavioral Deficits That Can Be Improved by Neurosteroid-Based Treatment.

Published in:

Frontiers in Cellular Neuroscience, 2017, p. 1, doi. 10.3389/fncel.2017.00208

By:

Locci, Andrea;
Geoffroy, Philippe;
Miesch, Michel;
Mensah-Nyagan, Ayikoe-Guy;
Pinna, Graziano

Publication type:

Article

Progesterone and Allopregnanolone Rapidly Attenuate Estrogen-Associated Mechanical Allodynia in Rats with Persistent Temporomandibular Joint Inflammation.

Published in:

Frontiers in Integrative Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnint.2020.00026

By:

Hornung, Rebecca S.;
Benton, William L.;
Tongkhuya, Sirima;
Uphouse, Lynda;
Kramer, Phillip R.;
Averitt, Dayna Loyd

Publication type:

Article