Works matching DE "PREGNANE X receptor"
Results: 390
The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model.
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- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56642-y
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- Article
Restoration of Memory Potential by Piper betel Leaves Extract in High-Fat Diet (HFD)-Induced Dementia in Mice.
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- Journal of Drug Delivery & Therapeutics, 2025, v. 15, n. 1, p. 19, doi. 10.22270/jddt.v15i1.6943
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- Article
Indole-3-propionic acid alleviates sepsis-associated acute liver injury by activating pregnane X receptor.
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- Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00658-x
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- Article
Boost-RS: boosted embeddings for recommender systems and its application to enzyme–substrate interaction prediction.
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- Bioinformatics, 2022, v. 38, n. 10, p. 2832, doi. 10.1093/bioinformatics/btac201
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- Article
Protective effects of spironolactone against hepatic ischemia/reperfusion injury in rats.
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- Turkish Journal of Surgery / Bilimsel Tip Yayinevi, 2019, v. 35, n. 4, p. 285, doi. 10.5578/turkjsurg.4340
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- Article
RECENT ADVANCES IN COMPUTATIONAL CHEMISTRY FOR IDENTIFICATION OF LIGANDS FOR BIOLOGICAL RECEPTORS: INTERDISCIPLINARY ASPECTS.
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- Medical Science Pulse, 2018, v. 12, n. 1, p. 12, doi. 10.5604/01.3001.0011.6670
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- Article
Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure.
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- Environmental Toxicology, 2017, v. 32, n. 3, p. 1024, doi. 10.1002/tox.22301
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- Publication type:
- Article
TNF-α对非小细胞肺癌中NF-κB/PXR信号通路和去SUMO化修饰的调控作用.
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- Progress in Modern Biomedicine, 2020, v. 20, n. 17, p. 3221, doi. 10.13241/j.cnki.pmb.2020.17.005
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- Article
Impact of various high fat diets on gene expression and the microbiome across the mouse intestines.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-49555-7
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- Article
Meclizine Prevents Ovariectomy-Induced Bone Loss and Inhibits Osteoclastogenesis Partially by Upregulating PXR.
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- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00693
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- Article
Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X Receptor.
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- Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00084
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- Article
Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions.
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- Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00456
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- Publication type:
- Article
Gut Microbiota Interplay With COVID-19 Reveals Links to Host Lipid Metabolism Among Middle Eastern Populations.
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- Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.761067
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- Article
A Comparative Genomic and Phylogenetic Investigation of the Xenobiotic Metabolism Enzymes of Cytochrome P450 in Elephants Shows Loss in CYP2E and CYP4A.
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- Animals (2076-2615), 2023, v. 13, n. 12, p. 1939, doi. 10.3390/ani13121939
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- Article
Effect of Pregnane X Receptor on CYP3A29 Expression in Porcine Alveolar Macrophages during Mycoplasma hyopneumoniae Infection.
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- Animals (2076-2615), 2021, v. 11, n. 2, p. 349, doi. 10.3390/ani11020349
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- Article
Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39118-9
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- Article
The role of pregnane X receptor (PXR) in substance metabolism.
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- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.959902
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- Article
The role of pregnane X receptor (PXR) in substance metabolism.
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- Frontiers in Endocrinology, 2022, v. 13, p. 01, doi. 10.3389/fendo.2022.959902
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- Publication type:
- Article
Role of nuclear pregnane X receptor in Cu-induced lipid metabolism and xenobiotic responses in largemouth bass (Micropterus salmoides).
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- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.950985
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- Publication type:
- Article
Regulation of Biotransformation Systems and ABC Transporters by Benznidazole in HepG2 Cells: Involvement of Pregnane X-Receptor.
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- PLoS Neglected Tropical Diseases, 2012, v. 6, n. 12, p. 1, doi. 10.1371/journal.pntd.0001951
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- Article
An evaluation of the anti-inflammatory properties of the pregnane X receptor gene isoforms PXR1 and PXR3.
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- 2019
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- Publication type:
- Letter
An evaluation of the anti-inflammatory properties of the pregnane X receptor gene isoforms PXR1 and PXR3.
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- 2019
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- Publication type:
- Letter
Novel receptor targets for production and action of allopregnanolone in the central nervous system: a focus on pregnane xenobiotic receptor.
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- Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00106
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- Publication type:
- Article
Meclizine ameliorates memory deficits in streptozotocin-induced experimental dementia in mice: role of nuclear pregnane X receptors.
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- Canadian Journal of Physiology & Pharmacology, 2020, v. 98, n. 6, p. 383, doi. 10.1139/cjpp-2019-0421
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- Publication type:
- Article
Mechanisms of NADPH – cytochrome P450 oxidoreductase induction by dexamethasone in the H4IIE rat hepatoma cell line.
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- Canadian Journal of Physiology & Pharmacology, 2020, v. 98, n. 5, p. 267, doi. 10.1139/cjpp-2019-0586
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- Publication type:
- Article
Dose-dependent difference of nuclear receptors involved in murine liver hypertrophy by piperonyl butoxide.
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- Journal of Toxicological Sciences, 2015, v. 40, n. 6, p. 787, doi. 10.2131/jts.40.787
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- Article
Response of xenobiotic biodegradation and metabolic genes in Tribolium castaneum following eugenol exposure.
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- Molecular Genetics & Genomics, 2022, v. 297, n. 3, p. 801, doi. 10.1007/s00438-022-01890-6
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- Publication type:
- Article
Bidirectional pharmacokinetic drug interactions between olaparib and metformin.
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- Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 1, p. 79, doi. 10.1007/s00280-023-04591-y
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- Publication type:
- Article
Effects of polymorphisms in pregnane X receptor and ABC transporters on afatinib in Japanese patients with non-small cell lung cancer: pharmacogenomic–pharmacokinetic and exposure–response analysis.
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- Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 4, p. 315, doi. 10.1007/s00280-023-04569-w
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- Article
Megestrol acetate is a specific inducer of CYP3A4 mediated by human pregnane X receptor.
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- 2021
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- Publication type:
- journal article
Exposure to a PFOA, PFOS and PFHxS Mixture during Gestation and Lactation Alters the Liver Proteome in Offspring of CD-1 Mice.
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- Toxics, 2024, v. 12, n. 5, p. 348, doi. 10.3390/toxics12050348
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- Publication type:
- Article
Using Hepatic Gene Expression Assays in English Sole (Parophrys vetulus) to Investigate the Effects of Metro Vancouver Wastewater Effluents.
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- Toxics, 2023, v. 11, n. 8, p. 657, doi. 10.3390/toxics11080657
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- Publication type:
- Article
Pregnane X receptor expression in skin: the good and the bad.
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- 2015
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- Publication type:
- Opinion
Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor.
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- Experimental Dermatology, 2015, v. 24, n. 11, p. 835, doi. 10.1111/exd.12766
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- Article
Synergistic Steatosis Induction in Mice: Exploring the Interactions and Underlying Mechanisms between PFOA and Tributyltin.
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- Cells (2073-4409), 2024, v. 13, n. 11, p. 940, doi. 10.3390/cells13110940
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- Publication type:
- Article
Pregnane X Receptor Signaling Pathway and Vitamin K: Molecular Mechanisms and Clinical Relevance in Human Health.
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- Cells (2073-4409), 2024, v. 13, n. 8, p. 681, doi. 10.3390/cells13080681
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- Publication type:
- Article
AhR, PXR and CAR: From Xenobiotic Receptors to Metabolic Sensors.
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- Cells (2073-4409), 2023, v. 12, n. 23, p. 2752, doi. 10.3390/cells12232752
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- Publication type:
- Article
Okadaic Acid Activates JAK/STAT Signaling to Affect Xenobiotic Metabolism in HepaRG Cells.
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- Cells (2073-4409), 2023, v. 12, n. 5, p. 770, doi. 10.3390/cells12050770
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- Publication type:
- Article
Combination of Paclitaxel and PXR Antagonist SPA70 Reverses Paclitaxel-Resistant Non-Small Cell Lung Cancer.
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- Cells (2073-4409), 2022, v. 11, n. 19, p. 3094, doi. 10.3390/cells11193094
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- Publication type:
- Article
Allosteric Antagonism of the Pregnane X Receptor (PXR): Current-State-of-the-Art and Prediction of Novel Allosteric Sites.
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- Cells (2073-4409), 2022, v. 11, n. 19, p. 2974, doi. 10.3390/cells11192974
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- Publication type:
- Article
Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library.
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- Cells (2073-4409), 2022, v. 11, n. 8, p. 1299, doi. 10.3390/cells11081299
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- Publication type:
- Article
Development and Experimental Validation of Regularized Machine Learning Models Detecting New, Structurally Distinct Activators of PXR.
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- Cells (2073-4409), 2022, v. 11, n. 8, p. 1253, doi. 10.3390/cells11081253
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- Publication type:
- Article
Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia.
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- Cells (2073-4409), 2022, v. 11, n. 3, p. 313, doi. 10.3390/cells11030313
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- Publication type:
- Article
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
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- Cells (2073-4409), 2022, v. 11, n. 2, p. 264, doi. 10.3390/cells11020264
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- Publication type:
- Article
The Nuclear Receptor PXR in Chronic Liver Disease.
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- Cells (2073-4409), 2022, v. 11, n. 1, p. 61, doi. 10.3390/cells11010061
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- Publication type:
- Article
PXR Suppresses PPARα-Dependent HMGCS2 Gene Transcription by Inhibiting the Interaction between PPARα and PGC1α.
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- Cells (2073-4409), 2021, v. 10, n. 12, p. 3550, doi. 10.3390/cells10123550
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- Publication type:
- Article
Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes.
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- Cells (2073-4409), 2021, v. 10, n. 12, p. 3381, doi. 10.3390/cells10123381
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- Article
The Interface between Cell Signaling Pathways and Pregnane X Receptor.
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- Cells (2073-4409), 2021, v. 10, n. 11, p. 3262, doi. 10.3390/cells10113262
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- Publication type:
- Article
Regulation of PXR Function by Coactivator and Corepressor Proteins: Ligand Binding Is Just the Beginning.
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- Cells (2073-4409), 2021, v. 10, n. 11, p. 3137, doi. 10.3390/cells10113137
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- Publication type:
- Article
PXR and 4β-Hydroxycholesterol Axis and the Components of Metabolic Syndrome.
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- Cells (2073-4409), 2020, v. 9, n. 11, p. 2445, doi. 10.3390/cells9112445
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- Publication type:
- Article