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Flucloxacillin instantly decreases serum levels of valproic acid: A case report.
- Published in:
- British Journal of Clinical Pharmacology, 2024, v. 90, n. 11, p. 2931, doi. 10.1111/bcp.16244
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- Publication type:
- Article
PXR haplotype clusters will affect the pharmacokinetics of ciclosporin in Chinese renal transplant recipients.
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- Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 2, p. 271, doi. 10.1111/jphp.13206
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- Publication type:
- Article
Female‐to‐male differential transcription patterns of miRNA‐mRNA networks in the livers of dioxin‐exposed mice.
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- Environmental Toxicology, 2023, v. 38, n. 10, p. 2310, doi. 10.1002/tox.23868
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- Publication type:
- Article
Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure.
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- Environmental Toxicology, 2017, v. 32, n. 3, p. 1024, doi. 10.1002/tox.22301
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- Publication type:
- Article
TNF-α对非小细胞肺癌中NF-κB/PXR信号通路和去SUMO化修饰的调控作用.
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- Progress in Modern Biomedicine, 2020, v. 20, n. 17, p. 3221, doi. 10.13241/j.cnki.pmb.2020.17.005
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- Article
Pregnenolone protects the liver against doxorubicin-induced cellular injury by anti-inflammatory, antioxidant, and antiapoptotic mechanisms: role of Keap1/Nrf2/HO-1 and P-glycoprotein.
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- European Review for Medical & Pharmacological Sciences, 2023, v. 27, n. 10, p. 4718
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- Publication type:
- Article
Evaluation of a novel PXR-knockout in HepaRG<sup>™</sup> cells.
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- Pharmacology Research & Perspectives, 2016, v. 4, n. 5, p. n/a, doi. 10.1002/prp2.264
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- Article
Constitutive androstane receptor and pregnane X receptor genotype influence efavirenz plasma concentration and CYP2B6 enzyme activity.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14032-0
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- Publication type:
- Article
Applying PICRUSt and 16S rRNA functional characterisation to predicting co-digestion strategies of various animal manures for biogas production.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99389-4
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- Publication type:
- Article
Involvement of endoplasmic reticulum stress in rifampicin-induced liver injury.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1022809
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- Publication type:
- Article
In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.826395
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- Publication type:
- Article
Identifying Drug-Induced Liver Injury Associated With Inflammation-Drug and Drug-Drug Interactions in Pharmacologic Treatments for COVID-19 by Bioinformatics and System Biology Analyses: The Role of Pregnane X Receptor.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.804189
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- Publication type:
- Article
Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.881231
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- Publication type:
- Article
Deciphering the Underlying Mechanisms of Formula Le-Cao-Shi Against Liver Injuries by Integrating Network Pharmacology, Metabonomics, and Experimental Validation.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.884480
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- Publication type:
- Article
Salvia miltiorrhiza Bunge (Danshen) and Bioactive Compound Tanshinone IIA Alleviates Cisplatin-Induced Acute Kidney Injury Through Regulating PXR/NF-κB Signaling.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.860383
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- Publication type:
- Article
Derivation of a Human In Vivo Benchmark Dose for Bisphenol A from ToxCast In Vitro Concentration Response Data Using a Computational Workflow for Probabilistic Quantitative In Vitro to In Vivo Extrapolation.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2021.754408
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- Publication type:
- Article
Deorphanizing solute carriers in Saccharomyces cerevisiae for secondary uptake of xenobiotic compounds.
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- Frontiers in Microbiology, 2024, p. 01, doi. 10.3389/fmicb.2024.1376653
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- Publication type:
- Article
Application of artificial intelligence approaches to predict the metabolism of xenobiotic molecules by human gut microbiome.
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- Frontiers in Microbiology, 2023, p. 1, doi. 10.3389/fmicb.2023.1254073
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- Publication type:
- Article
Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila.
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- Membranes, 2021, v. 11, n. 6, p. 432, doi. 10.3390/membranes11060432
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- Publication type:
- Article
Tryptophan and the innate intestinal immunity: Crosstalk between metabolites, host innate immune cells, and microbiota.
- Published in:
- European Journal of Immunology, 2022, v. 52, n. 6, p. 856, doi. 10.1002/eji.202149401
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- Publication type:
- Article
Effects of Isosakuranetin on Pharmacokinetic Changes of Tofacitinib in Rats with N -Dimethylnitrosamine-Induced Liver Cirrhosis.
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- Pharmaceutics, 2022, v. 14, n. 12, p. 2684, doi. 10.3390/pharmaceutics14122684
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- Publication type:
- Article
Time-Resolved Effect of Interferon-Alpha 2a on Activities of Nuclear Factor Kappa B, Pregnane X Receptor and on Drug Disposition Genes.
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- Pharmaceutics, 2021, v. 13, n. 6, p. 808, doi. 10.3390/pharmaceutics13060808
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- Publication type:
- Article
The Role of PXR Genotype and Transporter Expression in the Placental Transport of Lopinavir in Mice.
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- Pharmaceutics, 2017, v. 9, n. 4, p. 49, doi. 10.3390/pharmaceutics9040049
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- Publication type:
- Article
Nuclear Receptors and Stress Response Pathways Associated with the Development of Oral Mucositis Induced by Antineoplastic Agents.
- Published in:
- Pharmaceuticals (14248247), 2024, v. 17, n. 8, p. 1086, doi. 10.3390/ph17081086
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- Publication type:
- Article
Safety Implications of Modulating Nuclear Receptors: A Comprehensive Analysis from Non-Clinical and Clinical Perspectives.
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- Pharmaceuticals (14248247), 2024, v. 17, n. 7, p. 875, doi. 10.3390/ph17070875
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- Publication type:
- Article
Exploring Microbial Metabolite Receptors in Inflammatory Bowel Disease: An In Silico Analysis of Their Potential Role in Inflammation and Fibrosis.
- Published in:
- Pharmaceuticals (14248247), 2024, v. 17, n. 4, p. 492, doi. 10.3390/ph17040492
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- Publication type:
- Article
Back Cover.
- Published in:
- Chinese Journal of Chemistry, 2022, v. 40, n. 22, p. 2716, doi. 10.1002/cjoc.202290225
- Publication type:
- Article
Applanoids A—E as the First Examples of C‐15/C‐20 Michael Adducts in Ganoderma Triterpenoids and Their PXR Agonistic Activity.
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- Chinese Journal of Chemistry, 2022, v. 40, n. 22, p. 2633, doi. 10.1002/cjoc.202200318
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- Publication type:
- Article
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
- Published in:
- International Journal of Endocrinology, 2021, p. 1, doi. 10.1155/2021/8867218
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- Article
Mechanism of tangshen formula in treating diabetic nephropathy revealed by network pharmacology approach.
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- 2021
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- Publication type:
- journal article
An evaluation of the anti-inflammatory properties of the pregnane X receptor gene isoforms PXR1 and PXR3.
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- 2019
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- Publication type:
- Letter
An evaluation of the anti-inflammatory properties of the pregnane X receptor gene isoforms PXR1 and PXR3.
- Published in:
- 2019
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- Publication type:
- Letter
Improved Urinary Cortisol Metabolome in Addison Disease: A Prospective Trial of Dual-Release Hydrocortisone.
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- 2021
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- Publication type:
- journal article
Molecular Factors and Pathways of Hepatotoxicity Associated with HIV/SARS-CoV-2 Protease Inhibitors.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 7938, doi. 10.3390/ijms24097938
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- Publication type:
- Article
Macrophage-Specific Coxsackievirus and Adenovirus Receptor Deletion Enhances Macrophage M1 Polarity in CVB3-Induced Myocarditis.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5309, doi. 10.3390/ijms24065309
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- Publication type:
- Article
Allopregnanolone: Metabolism, Mechanisms of Action, and Its Role in Cancer.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 560, doi. 10.3390/ijms24010560
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- Publication type:
- Article
Establishment and Characterization of Novel Human Intestinal In Vitro Models for Absorption and First-Pass Metabolism Studies.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9861, doi. 10.3390/ijms23179861
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- Publication type:
- Article
(-)-Epicatechin Is a Biased Ligand of Apelin Receptor.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 8962, doi. 10.3390/ijms23168962
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- Publication type:
- Article
Effects of Cryopreservation on Sperm with Cryodiluent in Viviparous Black Rockfish (Sebastes schlegelii).
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- International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3392, doi. 10.3390/ijms23063392
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- Publication type:
- Article
4- O -Glucosylation of Trichothecenes by Fusarium Species: A Phase II Xenobiotic Metabolism for t-Type Trichothecene Producers.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13542, doi. 10.3390/ijms222413542
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- Publication type:
- Article
Indole-3-Propionic Acid, a Functional Metabolite of Clostridium sporogenes , Promotes Muscle Tissue Development and Reduces Muscle Cell Inflammation.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12435, doi. 10.3390/ijms222212435
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- Publication type:
- Article
New Insights on Vitamin K Metabolism in Senegalese sole (Solea senegalensis) Based on Ontogenetic and Tissue-Specific Vitamin K Epoxide Reductase Molecular Data.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 10, p. 3489, doi. 10.3390/ijms21103489
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- Publication type:
- Article
Modulatory Effects of Silymarin on Benzo[a]pyrene-Induced Hepatotoxicity.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2369, doi. 10.3390/ijms21072369
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- Publication type:
- Article
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 18, p. 4562, doi. 10.3390/ijms20184562
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- Publication type:
- Article
Gene Expression Profiling Reveals that PXR Activation Inhibits Hepatic PPARα Activity and Decreases FGF21 Secretion in Male C57Bl6/J Mice.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 15, p. 3767, doi. 10.3390/ijms20153767
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- Publication type:
- Article
Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2331, doi. 10.3390/ijms20092331
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- Publication type:
- Article
Mathematical Models in the Description of Pregnane X Receptor (PXR)-Regulated Cytochrome P450 Enzyme Induction.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 6, p. 1785, doi. 10.3390/ijms19061785
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- Publication type:
- Article
A Functional Polymorphism in the 3'-UTR of PXR Interacts with Smoking to Increase Lung Cancer Risk in Southern and Eastern Chinese Smoker.
- Published in:
- International Journal of Molecular Sciences, 2014, v. 15, n. 10, p. 17457, doi. 10.3390/ijms151017457
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- Publication type:
- Article
A multi-omics approach to elucidate okadaic acid-induced changes in human HepaRG hepatocarcinoma cells.
- Published in:
- Archives of Toxicology, 2024, v. 98, n. 9, p. 2919, doi. 10.1007/s00204-024-03796-1
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- Publication type:
- Article
Metabolic effects of nuclear receptor activation in vivo after 28-day oral exposure to three endocrine-disrupting chemicals.
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- Archives of Toxicology, 2024, v. 98, n. 3, p. 911, doi. 10.1007/s00204-023-03658-2
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- Publication type:
- Article