Works matching DE "POLYGLUTAMINE"
Results: 443
Dimerization of Polyglutamine within the PRIME20 Model using Stochastic Approximation Monte Carlo.
- Published in:
- Macromolecular Theory & Simulations, 2023, v. 32, n. 5, p. 1, doi. 10.1002/mats.202200075
- By:
- Publication type:
- Article
A theoretical study of monomeric polyglutamine chains from molecular dynamics simulations with explicit water.
- Published in:
- Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2018, v. 137, n. 1, p. 1, doi. 10.1007/s00214-017-2172-1
- By:
- Publication type:
- Article
The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
- Published in:
- Acta Neuropathologica, 2017, v. 134, n. 6, p. 839, doi. 10.1007/s00401-017-1770-2
- By:
- Publication type:
- Article
Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet.
- Published in:
- Acta Neuropathologica, 2016, v. 132, n. 1, p. 127, doi. 10.1007/s00401-016-1550-4
- By:
- Publication type:
- Article
The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice.
- Published in:
- Acta Neuropathologica, 2014, v. 128, n. 5, p. 705, doi. 10.1007/s00401-014-1289-8
- By:
- Publication type:
- Article
FTLD-ALS of TDP-43 type and SCA2 in a family with a full ataxin-2 polyglutamine expansion.
- Published in:
- 2014
- By:
- Publication type:
- Report
Androgen-dependent impairment of myogenesis in spinal and bulbar muscular atrophy.
- Published in:
- Acta Neuropathologica, 2013, v. 126, n. 1, p. 109, doi. 10.1007/s00401-013-1122-9
- By:
- Publication type:
- Article
Coexistence of Huntington's disease and amyotrophic lateral sclerosis: a clinicopathologic study.
- Published in:
- Acta Neuropathologica, 2012, v. 124, n. 5, p. 749, doi. 10.1007/s00401-012-1005-5
- By:
- Publication type:
- Article
Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions.
- Published in:
- Acta Neuropathologica, 2012, v. 124, n. 2, p. 221, doi. 10.1007/s00401-012-0985-5
- By:
- Publication type:
- Article
Long-term proteasomal inhibition in transgenic mice by UBB expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients.
- Published in:
- Acta Neuropathologica, 2012, v. 124, n. 2, p. 187, doi. 10.1007/s00401-012-1003-7
- By:
- Publication type:
- Article
Ubiquilin immunoreactivity in cytoplasmic and nuclear inclusions in synucleinopathies, polyglutamine diseases and intranuclear inclusion body disease.
- Published in:
- 2012
- By:
- Publication type:
- Letter
Brain pathology of spinocerebellar ataxias.
- Published in:
- Acta Neuropathologica, 2012, v. 124, n. 1, p. 1, doi. 10.1007/s00401-012-1000-x
- By:
- Publication type:
- Article
Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington's, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease.
- Published in:
- 2012
- By:
- Publication type:
- Letter
A patient presenting downbeat positioning nystagmus with 19/11 CAG repeats in the CACNA1A gene: A case report.
- Published in:
- Neurology & Clinical Neuroscience, 2024, v. 12, n. 6, p. 359, doi. 10.1111/ncn3.12824
- By:
- Publication type:
- Article
The Missing Link in Polyglutamine Diseases.
- Published in:
- Movement Disorders Clinical Practice, 2018, v. 5, n. 1, p. 29, doi. 10.1002/mdc3.12558
- By:
- Publication type:
- Article
Distribution of polyglutamine proteins in Purkinje cells of the human and rat cerebellum.
- Published in:
- Journal of Evolutionary Biochemistry & Physiology, 2017, v. 53, n. 4, p. 340, doi. 10.1134/S0022093017040111
- By:
- Publication type:
- Article
Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington’s disease.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.89782
- By:
- Publication type:
- Article
Possible Role for Allelic Variation in Yeast MED15 in Ecological Adaptation.
- Published in:
- Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.741572
- By:
- Publication type:
- Article
Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.
- Published in:
- BioEssays, 2013, v. 35, n. 6, p. 503, doi. 10.1002/bies.201300001
- By:
- Publication type:
- Article
A novel target for Huntington's disease: ERK at the crossroads of signaling.
- Published in:
- BioEssays, 2012, v. 34, n. 2, p. 142, doi. 10.1002/bies.201100116
- By:
- Publication type:
- Article
SUMO-1 promotes degradation of the polyglutamine disease protein ataxin-3.
- Published in:
- Animal Cells & Systems, 2013, v. 17, n. 1, p. 7, doi. 10.1080/19768354.2012.738611
- By:
- Publication type:
- Article
The emerging role of the first 17 amino acids of huntingtin in Huntington's disease.
- Published in:
- Biomolecular Concepts, 2015, v. 6, n. 1, p. 33, doi. 10.1515/bmc-2015-0001
- By:
- Publication type:
- Article
Autophagy-related gene 7 is downstream of heat shock protein 27 in the regulation of eye morphology, polyglutamine toxicity, and lifespan in Drosophila.
- Published in:
- Journal of Biomedical Science, 2012, v. 19, n. 1, p. 52, doi. 10.1186/1423-0127-19-52
- Publication type:
- Article
Hsp104-dependent ability to assimilate mannitol and sorbitol conferred by a truncated Cyc8 with a C-terminal polyglutamine in Saccharomyces cerevisiae.
- Published in:
- PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0242054
- By:
- Publication type:
- Article
Reduction of Huntington's Disease RNA Foci by CAG Repeat-Targeting Reagents.
- Published in:
- Frontiers in Cellular Neuroscience, 2017, v. 11, p. 1, doi. 10.3389/fncel.2017.00082
- By:
- Publication type:
- Article
Regulation of mRNA Translation by MID1: A Common Mechanism of Expanded CAG Repeat RNAs.
- Published in:
- Frontiers in Cellular Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fncel.2016.00226
- By:
- Publication type:
- Article
Stem cell models of polyglutamine diseases and their use in cell-based therapies.
- Published in:
- Frontiers in Cellular Neuroscience, 2015, p. 1, doi. 10.3389/fnins.2015.00247
- By:
- Publication type:
- Article
Molecular mechanism of Spinocerebellar Ataxia type 6: glutamine repeat disorder, channelopathy and transcriptional dysregulation. The multifaceted aspects of a single mutation.
- Published in:
- Frontiers in Cellular Neuroscience, 2015, v. 8/9, p. 1, doi. 10.3389/fncel.2015.00036
- By:
- Publication type:
- Article
RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis.
- Published in:
- Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00431
- By:
- Publication type:
- Article
Editorial: The role of posttranslational modifications in polyglutamine diseases.
- Published in:
- Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1271226
- By:
- Publication type:
- Article
A survey of protein interactions and posttranslational modifications that influence the polyglutamine diseases.
- Published in:
- Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.974167
- By:
- Publication type:
- Article
Inherent Conformational Preferences of Ac-Gln-Gln-NHBn: Sidechain Hydrogen Bonding Supports a β-Turn in the Gas Phase.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 47, p. 14618, doi. 10.1002/anie.201607842
- By:
- Publication type:
- Article
Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0261-9
- By:
- Publication type:
- Article
Piperine ameliorates SCA17 neuropathology by reducing ER stress.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, p. 1, doi. 10.1186/s13024-018-0236-x
- By:
- Publication type:
- Article
ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0141-0
- By:
- Publication type:
- Article
Making (anti-) sense out of huntingtin levels in Huntington disease.
- Published in:
- Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0018-7
- By:
- Publication type:
- Article
Pathogenic polyglutamine expansion length correlates with polarity of the flanking sequences.
- Published in:
- Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-45
- By:
- Publication type:
- Article
p53-mediated disruption of FIP200 function cause autophagic dysregulation in a SCA7 polyglutamine disease model.
- Published in:
- 2013
- By:
- Publication type:
- Abstract
Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.
- Published in:
- Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 2, doi. 10.1186/1750-1326-8-45
- By:
- Publication type:
- Article
The Role of the Immune System in Triplet Repeat Expansion Diseases.
- Published in:
- Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/873860
- By:
- Publication type:
- Article
From the disruption of RNA metabolism to the targeting of RNA‐binding proteins: The case of polyglutamine spinocerebellar ataxias.
- Published in:
- Journal of Neurochemistry, 2024, v. 168, n. 8, p. 1442, doi. 10.1111/jnc.16010
- By:
- Publication type:
- Article
HNRNP Q suppresses polyglutamine huntingtin aggregation by post‐transcriptional regulation of vaccinia‐related kinase 2.
- Published in:
- Journal of Neurochemistry, 2019, v. 149, n. 3, p. 413, doi. 10.1111/jnc.14638
- By:
- Publication type:
- Article
Machado-Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy.
- Published in:
- Journal of Neurochemistry, 2019, v. 148, n. 1, p. 8, doi. 10.1111/jnc.14541
- By:
- Publication type:
- Article
In vivo assessment of riluzole as a potential therapeutic drug for spinocerebellar ataxia type 3.
- Published in:
- Journal of Neurochemistry, 2016, v. 138, n. 1, p. 150, doi. 10.1111/jnc.13606
- By:
- Publication type:
- Article
Glyceraldehyde 3-phosphate dehydrogenase augments the intercellular transmission and toxicity of polyglutamine aggregates in a cell model of Huntington disease.
- Published in:
- Journal of Neurochemistry, 2016, v. 136, n. 5, p. 1052, doi. 10.1111/jnc.13463
- By:
- Publication type:
- Article
Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the <i>Drosophila</i> Heart.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 12, p. 1, doi. 10.1371/journal.pgen.1004024
- By:
- Publication type:
- Article
Hsp104 Suppresses Polyglutamine-Induced Degeneration Post Onset in a Drosophila MJD/SCA3 Model.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.pgen.1003781
- By:
- Publication type:
- Article
ATXN2-CAG42 Sequesters PABPC1 into Insolubility and Induces FBXW8 in Cerebellum of Old Ataxic Knock-In Mice.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002920
- By:
- Publication type:
- Article
Identification of Human Proteins That Modify Misfolding and Proteotoxicity of Pathogenic Ataxin-1.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002897
- By:
- Publication type:
- Article
Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 4, p. 1, doi. 10.1371/journal.pgen.1002634
- By:
- Publication type:
- Article