Works matching DE "POLY ADP ribose"

Results: 950

circ_0000592 facilitates the progression of esophageal squamous cell carcinoma via miR‐155‐5p/FZD5 axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 6, p. 1, doi. 10.1002/jbt.23742

By:

He, Jinxian;
Yu, Kaizhong;
Liang, Gaofeng;
Shen, Weiyu;
Tian, Hui

Publication type:

Article

d‐ribose‐ l‐cysteine abrogates testicular maladaptive responses induced by polychlorinated bisphenol intoxication in rats via activation of the mTOR signaling pathway mediating inhibition of apoptosis, inflammation, and oxidonitrergic flux

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 10, p. 1, doi. 10.1002/jbt.23161

By:

Mega, Oyovwi O.;
Edesiri, Tesi P.;
Victor, Emojevwe;
Kingsley, Nwangwan E.;
Rume, Rotu A.;
Faith, Falajiki Y.;
Simon, Ovuakporaye I.;
Oghenetega, Bright O.;
Agbonifo‐Chijiokwu, Ejime

Publication type:

Article

Computational Analysis and Molecular Design of Aromatic Stacking System Between Human ARTD2 Catalytic Domain and its Small-Molecule Inhibitors and Peptidic Ligands.

Published in:

Journal of Computational Biophysics & Chemistry, 2022, v. 21, n. 5, p. 529, doi. 10.1142/S2737416522500181

By:

Liu, Rui;
Liu, Lijun

Publication type:

Article

PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02306-1

By:

Yano, Kimiyoshi;
Kato, Megumi;
Endo, Syoju;
Igarashi, Taichi;
Wada, Ryoga;
Kohno, Takashi;
Zimmermann, Astrid;
Dahmen, Heike;
Zenke, Frank T.;
Shiotani, Bunsyo

Publication type:

Article

CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02040-0

By:

Acharya, Ganesh;
Mani, Chinnadurai;
Sah, Naresh;
Saamarthy, Karunakar;
Young, Robert;
Reedy, Mark B.;
Sobol, Robert W.;
Palle, Komaraiah

Publication type:

Article

Transforming Breast Cancer Care: Cutting-Edge Insights and Future Directions.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 22, p. 6697, doi. 10.3390/jcm13226697

By:

De Sanctis, Rita;
Tiberio, Paola;
Zambelli, Alberto;
Santoro, Armando

Publication type:

Article

[ 18 F]F-Poly(ADP-Ribose) Polymerase Inhibitor Radiotracers for Imaging PARP Expression and Their Potential Clinical Applications in Oncology.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 12, p. 3426, doi. 10.3390/jcm13123426

By:

Ndlovu, Honest;
Lawal, Ismaheel O.;
Mdanda, Sipho;
Kgatle, Mankgopo M.;
Mokoala, Kgomotso M. G.;
Al-Ibraheem, Akram;
Sathekge, Mike M.

Publication type:

Article

The Present and Future of Clinical Management in Metastatic Breast Cancer.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 19, p. 5891, doi. 10.3390/jcm11195891

By:

Lin, Pauline H.;
Laliotis, George

Publication type:

Article

Advancements in PARP1 Targeted Nuclear Imaging and Theranostic Probes.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 7, p. 2130, doi. 10.3390/jcm9072130

By:

Ambur Sankaranarayanan, Ramya;
Kossatz, Susanne;
Weber, Wolfgang;
Beheshti, Mohsen;
Morgenroth, Agnieszka;
Mottaghy, Felix M.

Publication type:

Article

Response of Breast Cancer Cells to PARP Inhibitors Is Independent of BRCA Status.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 4, p. 940, doi. 10.3390/jcm9040940

By:

Keung, Man Yee;
Wu, Yanyuan;
Badar, Francesca;
Vadgama, Jaydutt V.

Publication type:

Article

KCP10043F Represses the Proliferation of Human Non-Small Cell Lung Cancer Cells by Caspase-Mediated Apoptosis via STAT3 Inactivation.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 3, p. 704, doi. 10.3390/jcm9030704

By:

Lee, Jeong-Hun;
Lee, Hwi-Ho;
Ryu, Ki Deok;
Kim, Misong;
Ko, Dohyeong;
Chung, Kyung-Sook;
Hassan, Ahmed H.E.;
Lee, Seung Hyeun;
Lee, Jae Yeol;
Lee, Kyung-Tae

Publication type:

Article

PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 4, p. 435, doi. 10.3390/jcm8040435

By:

Keung, Man Yee T.;
Wu, Yanyuan;
Vadgama, Jaydutt V.

Publication type:

Article

Clinical Impact of Olaparib for Platinum-Sensitive Recurrent Ovarian Cancer.

Published in:

Diseases, 2025, v. 13, n. 2, p. 51, doi. 10.3390/diseases13020051

By:

Ishida, Hiroaki;
Manrai, Megumi;
Takashima, Akiko;
Egashira, Hiroki;
Nonaka, Mizuki;
Shimada, Hideaki

Publication type:

Article

The CD73 immune checkpoint promotes tumor cell metabolic fitness.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84508

By:

Allard, David;
Cousineau, Isabelle;
Ma, Eric H.;
Allard, Bertrand;
Bareche, Yacine;
Fleury, Hubert;
Stagg, John

Publication type:

Article

In Vitro Cytotoxicity and Zebrafish Embryos Acute Toxicity Assessment of Ruthenium (II) Metal-based Complexes in Combination with PARP inhibitor.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2024, v. 20, p. 99

By:

Yusoh, Nur Aininie;
Saad, Norazalina;
Chia Suet Lin;
Gill, Martin R.;
Ahmad, Haslina

Publication type:

Article

A Novel Combination of Ruthenium Polypyridyl Complex, [Ru(dppz)2PiP]<sup>2+</sup> and PARP Inhibitor, NU1025 for Cancer Treatment.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2019, v. 15, p. 26

By:

Yusoh, N. A.;
Ahmad, H.;
Leong, S. W.;
Chia, S. L.

Publication type:

Article

Genetic perspectives on prostate cancer: unveiling the impact on targeted radionuclide therapies.

Published in:

Pakistan Journal of Nuclear Medicine, 2023, v. 13, n. 1, p. 13, doi. 10.24911/PJNMed.175-1696399353

By:

Shabbir, Hamid;
Imran, Muhammad Babar;
Rubab, Nayyar

Publication type:

Article

Zoletil promotes apoptosis in BV-2 microglial cells via induction of oxidative stress and neural inflammation.

Published in:

Toxicology Research, 2022, v. 11, n. 1, p. 134, doi. 10.1093/toxres/tfab115

By:

Kim, Gyun Moo;
Lee, Chan;
Jang, Tae Chang

Publication type:

Article

Small-interfering RNA for c-Jun attenuates cell death by preventing JNK-dependent PARP1 cleavage and DNA fragmentation in nitrogen mustard-injured immortalized human bronchial epithelial cells.

Published in:

Toxicology Research, 2021, v. 10, n. 5, p. 1034, doi. 10.1093/toxres/tfab081

By:

Ye, Feng;
Dan, Guorong;
Zhao, Yuanpeng;
Yu, Wenpei;
Cheng, Jin;
Chen, Mingliang;
Sai, Yan;
Zou, Zhongmin

Publication type:

Article

Human Mass Balance and Metabolite Profiling of [<sup>14</sup>C]‐Pamiparib, a Poly (ADP‐Ribose) Polymerase Inhibitor, in Patients With Advanced Cancer.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 9, p. 1108, doi. 10.1002/cpdd.943

By:

Mu, Song;
Palmer, Daniel;
Fitzgerald, Richard;
Andreu‐Vieyra, Claudia;
Zhang, Heather;
Tang, Zhiyu;
Su, Dan;
Sahasranaman, Srikumar

Publication type:

Article

Drug Targeting of Genomic Instability in Multiple Myeloma.

Published in:

Frontiers in Genetics, 2020, p. 1, doi. 10.3389/fgene.2020.00228

By:

Beksac, Meral;
Balli, Sevinc;
Akcora Yildiz, Dilara

Publication type:

Article

Molecular insight into the π‐stacking interactions of human ovarian cancer PARP‐1 with its small‐molecule inhibitors and rational design of aromatic amino acid‐rich peptides to target PARP‐1 based on the π‐stacking network

Published in:

Journal of the Chinese Chemical Society, 2022, v. 69, n. 5, p. 775, doi. 10.1002/jccs.202200004

By:

Pan, Chunxia;
Chen, Lei;
Zhang, Xinxin;
Zhang, Depu;
Song, Quqing;
Peng, Jingwei;
Li, Qingshui

Publication type:

Article

Pleiotropic role of PARP1: an overview.

Published in:

3 Biotech, 2022, v. 12, n. 1, p. 1, doi. 10.1007/s13205-021-03038-6

By:

Kumar, Vikas;
Kumar, Anurag;
Mir, Khursheed Ul Islam;
Yadav, Vandana;
Chauhan, Shyam Singh

Publication type:

Article

Pleiotropic role of PARP1: an overview.

Published in:

3 Biotech, 2021, v. 12, n. 1, p. 1, doi. 10.1007/s13205-021-03038-6

By:

Kumar, Vikas;
Kumar, Anurag;
Mir, Khursheed Ul Islam;
Yadav, Vandana;
Chauhan, Shyam Singh

Publication type:

Article

O19 | DNA damage as a potential target in canine lymphoma treatment: A comparative transcriptomic evaluation of olaparib effects in two lymphoid cell lines.

Published in:: Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, p. 37, doi. 10.1111/jvp.13185
Publication type:: Article

Inhibition of WEE1 Potentiates Sensitivity to PARP Inhibitor in Biliary Tract Cancer.

Published in:

Cancer Research & Treatment, 2022, v. 54, n. 2, p. 541, doi. 10.4143/crt.2021.473

By:

Hye-Rim Seo;
Ah-Rong Nam;
Ju-Hee Bang;
Kyoung-Seok Oh;
Jae-Min Kim;
Jeesun Yoon;
Tae-Yong Kim;
Do-Youn Oh

Publication type:

Article

CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56085-5

By:

Provencher, Luc;
Nartey, Wilson;
Brownlee, Peter M.;
Atkins, Austin W.;
Gagné, Jean-Philippe;
Baudrier, Lou;
Ting, Nicholas S. Y.;
Piett, Cortt G.;
Fang, Shujuan;
Pearson, Dustin D.;
Moore, Shaun;
Billon, Pierre;
Nagel, Zachary D.;
Poirier, Guy G.;
Williams, Gareth J.;
Goodarzi, Aaron A.

Publication type:

Article

Regulation of stress granule maturation and dynamics by poly(ADP-ribose) interaction with PARP13.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-024-55666-0

By:

Cheng, Shang-Jung;
Gafaar, Temitope;
Kuttiyatveetil, Jijin R. A.;
Sverzhinsky, Aleksandr;
Chen, Carla;
Xu, Minghui;
Lilley, Allison;
Pascal, John M.;
Leung, Anthony K. L.

Publication type:

Article

SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51192-1

By:

Luo, Yu-Wei;
Zhou, Jiang-Peng;
Ji, Hongyu;
Xu, Doudou;
Zheng, Anqi;
Wang, Xin;
Dai, Zhizheng;
Luo, Zhicheng;
Cao, Fang;
Wang, Xing-Yue;
Bai, Yunfang;
Chen, Di;
Chen, Yueming;
Wang, Qi;
Yang, Yaying;
Zhang, Xinghai;
Chiu, Sandra;
Peng, Xiaozhong;
Huang, Ai-Long;
Tang, Kai-Fu

Publication type:

Article

Histone-methyltransferase KMT2D deficiency impairs the Fanconi anemia/BRCA pathway upon glycolytic inhibition in squamous cell carcinoma.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50861-5

By:

Liu, Wei;
Cao, Hongchao;
Wang, Jing;
Elmusrati, Areeg;
Han, Bing;
Chen, Wei;
Zhou, Ping;
Li, Xiyao;
Keysar, Stephen;
Jimeno, Antonio;
Wang, Cun-Yu

Publication type:

Article

Nucleolytic processing of abasic sites underlies PARP inhibitor hypersensitivity in ALC1-deficient BRCA mutant cancer cells.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50673-7

By:

Ramakrishnan, Natasha;
Weaver, Tyler M.;
Aubuchon, Lindsey N.;
Woldegerima, Ayda;
Just, Taylor;
Song, Kevin;
Vindigni, Alessandro;
Freudenthal, Bret D.;
Verma, Priyanka

Publication type:

Article

The role of poly(ADP-ribose) polymerase inhibitors in the treatment of cancer and methods to overcome resistance: a review.

Published in:

Cell & Bioscience, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13578-020-00390-7

By:

Patel, Mausam;
Nowsheen, Somaira;
Maraboyina, Sanjay;
Xia, Fen

Publication type:

Article

MSC-derived exosomes attenuate cell death through suppressing AIF nucleus translocation and enhance cutaneous wound healing.

Published in:

Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. 1, doi. 10.1186/s13287-020-01616-8

By:

Zhao, Guifang;
Liu, Feilin;
Liu, Zinan;
Zuo, Kuiyang;
Wang, Bo;
Zhang, Yuying;
Han, Xing;
Lian, Aobo;
Wang, Yuan;
Liu, Mingsheng;
Zou, Fei;
Li, Pengdong;
Liu, Xiaomei;
Jin, Minghua;
Liu, Jin Yu

Publication type:

Article

[Corrigendum] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis.

Published in:

2025

By:

Chen, Jun;
Zhang, Ting;
Luo, Qingqing;
Wang, Ruyi;
Dai, Yuting;
Chen, Zhenyuan;
Zhang, Chutian;
Chen, Xuzheng;
Wu, Guangwen

Publication type:

Correction Notice

Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis.

Published in:

Molecular Medicine Reports, 2024, v. 29, n. 6, p. N.PAG, doi. 10.3892/mmr.2024.13226

By:

Chen, Jun;
Zhang, Ting;
Luo, Qingqing;
Wang, Ruyi;
Dai, Yuting;
Chen, Zhenyuan;
Zhang, Chutian;
Chen, Xuzheng;
Wu, Guangwen

Publication type:

Article

3,4-Dihydroxyacetophenone attenuates oxidative stress-induced damage to HUVECs via regulation of the Nrf2/HO-1 pathway.

Published in:

Molecular Medicine Reports, 2022, v. 25, n. 6, p. N.PAG, doi. 10.3892/mmr.2022.12715

By:

Cao, Daihong;
Wang, Yunhan;
Li, Wentao;
Ji, Jiafen;
Guo, Juntang;
Zhang, Daijuan;
Liu, Jiangyue

Publication type:

Article

Two PARP13 isoforms are associated with induction of antiviral factors in oral mucosal cells.

Published in:

Molecular Medicine Reports, 2022, v. 25, n. 3, p. N.PAG, doi. 10.3892/mmr.2022.12622

By:

Kato, Hiroki;
Ohta, Kouji;
Sakuma, Miyuki;
Fukada, Shohei;
Naruse, Takako;
Shigeishi, Hideo;
Nishi, Hiromi;
Takechi, Masaaki

Publication type:

Article

FOXG1 improves mitochondrial function and promotes the progression of nasopharyngeal carcinoma.

Published in:

Molecular Medicine Reports, 2021, v. 24, n. 3, p. N.PAG, doi. 10.3892/mmr.2021.12290

By:

Xi, Huajun;
He, Zhengxiang;
Lv, Cao

Publication type:

Article

PARP inhibitor resistance and TP53 mutations in patients treated with olaparib for BRCA-mutated cancer: Four case reports.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 1, p. N.PAG

By:

Collot, Thomas;
Niogret, Julie;
Carnet, Marion;
Chevrier, Sandy;
Humblin, Etienne;
Favier, Laure;
Bengrine-Lefevre, Leila;
Desmoulins, Isabelle;
Arnould, Laurent;
Boidot, Romain

Publication type:

Article

Tanshinone I and simvastatin inhibit melanoma tumour cell growth by regulating poly (ADP ribose) polymerase 1 expression.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 1, p. N.PAG

By:

Zhang, Yuyan;
Huang, Jiusui;
Huang, Yapeng;
Zhang, Shike;
Wu, Weizhou;
Long, Hui;
Duan, Xiaolu;
Lai, Yongchang;
Wu, Wenqi

Publication type:

Article

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 6, p. 4877, doi. 10.3892/mmr.2020.11572

By:

JOONG‑SEOK WOO;
GANG‑SIK CHOO;
EUN‑SEON YOO;
SUNG‑HYUN KIM;
JAE‑HAN LEE;
SO‑HEE HAN;
HYEONG‑JIN KIM;
SOO‑HYUN JUNG;
YOUNG‑SEOK PARK;
BYEONG‑SOO KIM;
SANG‑KI KIM;
BYUNG‑KWON PARK;
SUNG‑DAE CHO;
JEONG‑SEOK NAM;
CHANG‑SUN CHOI;
JEONG‑HWAN CHE;
JI‑YOUN JUNG

Publication type:

Article

Antitumor effects of aconitine in A2780 cells via estrogen receptor β-mediated apoptosis, DNA damage and migration.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 3, p. 2318, doi. 10.3892/mmr.2020.11322

By:

Wang, Xiuying;
Lin, Yuanyuan;
Zheng, Yi

Publication type:

Article

Butorphanol protects PC12 cells against OGD/R-induced inflammation and apoptosis.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 3, p. 1969, doi. 10.3892/mmr.2020.11290

By:

Yang, Zijing;
Wang, Li;
Hu, Yingjun;
Wang, Feixiang

Publication type:

Article

PARP inhibitor re-sensitizes Adriamycin resistant leukemia cells through DNA damage and apoptosis.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 1, p. 75

By:

Wu, Jie;
Xiao, Sheng;
Yuan, Miaomiao;
Li, Qianyuan;
Xiao, Guangfen;
Wu, Wei;
Ouyang, Yuexian;
Huang, Lihua;
Yao, Chenjiao

Publication type:

Article

Rho-kinase signaling pathway promotes the expression of PARP to accelerate cardiomyocyte apoptosis in ischemia/reperfusion.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 2, p. 2002, doi. 10.3892/mmr.2017.6826

By:

HONGJUN BIAN;
YI ZHOU;
BIN YU;
DEYA SHANG;
FULI LIU;
BIN LI;
JIANNI QI

Publication type:

Article

Protective effect of diethylcarbamazine inhibits NF-κB activation in isoproterenol-induced acute myocardial infarction rat model through the PARP pathway.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 2, p. 1596, doi. 10.3892/mmr.2017.6695

By:

GUOWEI JIA;
MING ZAO;
XIAOYU LIU

Publication type:

Article

Plant Poly(ADP-Ribose) Polymerase 1 Is a Potential Mediator of Cross-Talk between the Cajal Body Protein Coilin and Salicylic Acid-Mediated Antiviral Defence.

Published in:

Viruses (1999-4915), 2023, v. 15, n. 6, p. 1282, doi. 10.3390/v15061282

By:

Spechenkova, Nadezhda;
Samarskaya, Viktoriya O.;
Kalinina, Natalya O.;
Zavriev, Sergey K.;
MacFarlane, S.;
Love, Andrew J.;
Taliansky, Michael

Publication type:

Article

The Antiviral Activities of Poly-ADP-Ribose Polymerases.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 4, p. 582, doi. 10.3390/v13040582

By:

Malgras, Mathilde;
Garcia, Magali;
Jousselin, Clément;
Bodet, Charles;
Lévêque, Nicolas;
Nisole, Sébastien

Publication type:

Article

En Guard! The Interactions between Adenoviruses and the DNA Damage Response.

Published in:

Viruses (1999-4915), 2020, v. 12, n. 9, p. 996, doi. 10.3390/v12090996

By:

Kleinberger, Tamar

Publication type:

Article

Coupling of PARP1-mediated chromatin structural changes to transcriptional RNA polymerase II elongation and cotranscriptional splicing.

Published in:

Epigenetics & Chromatin, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13072-019-0261-1

By:

Matveeva, Elena A.;
Al-Tinawi, Qamar M. H.;
Rouchka, Eric C.;
Fondufe-Mittendorf, Yvonne N.

Publication type:

Article