Works matching DE "POLO-like kinases"

Results: 147

Optimizing the Size of Micellar Nanoparticles for Efficient siRNA Delivery.

Published in:

Advanced Functional Materials, 2015, v. 25, n. 30, p. 4778, doi. 10.1002/adfm.201501548

By:

Liang, Shi;
Yang, Xian‐Zhu;
Du, Xiao‐Jiao;
Wang, Hong‐Xia;
Li, Hong‐Jun;
Liu, Wei‐Wei;
Yao, Yan‐Dan;
Zhu, Yan‐Hua;
Ma, Yin‐Chu;
Wang, Jun;
Song, Er‐Wei

Publication type:

Article

PLK1-associated microRNAs are correlated with pediatric medulloblastoma prognosis.

Published in:

Child's Nervous System, 2017, v. 33, n. 4, p. 609, doi. 10.1007/s00381-017-3366-5

By:

Pezuk, Julia;
Brassesco, María;
Oliveira, Ricardo;
Machado, Hélio;
Neder, Luciano;
Scrideli, Carlos;
Tone, Luiz

Publication type:

Article

Another string to the polo bow: a new mitotic role of PLK1 in centromere protection.

Published in:

2019

By:

Olukoga, Tomisin;
Fernández-Casañas, María;
Chan, Kok-Lung

Publication type:

Opinion

An oncoinformatics study to predict the inhibitory potential of recent FDA-approved anti-cancer drugs against human Polo-like kinase 1 enzyme: a step towards dual-target cancer medication.

Published in:

3 Biotech, 2019, v. 9, n. 3, p. 1, doi. 10.1007/s13205-019-1594-y

By:

Rizvi, Syed Mohd. Danish;
Alshammari, Abdulaziz Arif A.;
Almawkaa, Waleed Abdullah;
Ahmed, Abo Bakr F.;
Katamesh, Ahmed;
Alafnan, Ahmed;
Almutairi, Tariq J.;
Alshammari, Rakan F.

Publication type:

Article

Understanding the Polo Kinase machine.

Published in:

Oncogene, 2015, v. 34, n. 37, p. 4799, doi. 10.1038/onc.2014.451

By:

Archambault, V;
Lépine, G;
Kachaner, D

Publication type:

Article

A novel role for Plk4 in regulating cell spreading and motility.

Published in:

Oncogene, 2015, v. 34, n. 26, p. 3441, doi. 10.1038/onc.2014.275

By:

Rosario, C O;
Kazazian, K;
Zih, F S W;
Brashavitskaya, O;
Haffani, Y;
Xu, R S Z;
George, A;
Dennis, J W;
Swallow, C J

Publication type:

Article

Polo-Like Kinase 1: A Novel Target for the Treatment of Therapy-Resistant Mantle Cell Lymphoma.

Published in:

Lymphoma (2090309X), 2013, p. 1, doi. 10.1155/2013/782903

By:

Ahrens, Adam K.;
Chaturvedi, Nagendra K.;
Shukla, Ashima;
Nordgren, Tara M.;
Hegde, Ganapati V.;
Vose, Julie M.;
Joshi, Shantaram S.

Publication type:

Article

Quantitative chemical proteomics reveals a Plk1 inhibitor-compromised cell death pathway in human cells.

Published in:

Cell Research, 2014, v. 24, n. 9, p. 1141, doi. 10.1038/cr.2014.86

By:

Raab, Monika;
Pachl, Fiona;
Krämer, Andrea;
Kurunci-Csacsko, Elisabeth;
Dötsch, Christina;
Knecht, Rainald;
Becker, Sven;
Kuster, Bernhard;
Strebhardt, Klaus

Publication type:

Article

Polo-like kinase 1 inhibition causes decreased proliferation by cell cycle arrest, leading to cell death in glioblastoma.

Published in:

Cancer Gene Therapy, 2013, v. 20, n. 9, p. 499, doi. 10.1038/cgt.2013.46

By:

Pezuk, J A;
Brassesco, M S;
Morales, A G;
de Oliveira, J C;
de Paula Queiroz, R G;
Machado, H R;
Carlotti, C G;
Neder, L;
Scrideli, C A;
Tone, L G

Publication type:

Article

Expression of polo-like kinase 1 in pre-implantation stage murine somatic cell nuclear transfer embryos.

Published in:

Journal of Veterinary Science, 2019, v. 20, n. 1, p. 2, doi. 10.4142/jvs.2019.20.1.2

By:

Jeonghyeon Moon;
Sangho Roh

Publication type:

Article

Structural basis for the inhibition of Polo-like kinase 1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 9, p. 1047, doi. 10.1038/nsmb.2623

By:

Xu, Jun;
Shen, Chen;
Wang, Tao;
Quan, Junmin

Publication type:

Article

High levels of polo-like kinase 1 and phosphorylated translationally controlled tumor protein indicate poor prognosis in neuroblastomas.

Published in:

Journal of Neuro-Oncology, 2015, v. 125, n. 1, p. 103, doi. 10.1007/s11060-015-1900-4

By:

Ramani, Pramila;
Nash, Rachel;
Sowa-Avugrah, Emile;
Rogers, Chris

Publication type:

Article

PLK-1 Expression is Associated with Histopathological Response to Neoadjuvant Therapy of Hepatic Metastasis of Colorectal Carcinoma.

Published in:

Pathology & Oncology Research, 2016, v. 22, n. 2, p. 377, doi. 10.1007/s12253-015-0015-8

By:

Fernández-Aceñero, M.;
Cortés, D.;
Gómez del Pulgar, T.;
Cebrián, A.;
Estrada, L.;
Martínez-Useros, J.;
Celdrán, A.;
García-Foncillas, J.;
Pastor, C.

Publication type:

Article

Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis.

Published in:

Molecules, 2022, v. 27, n. 4, p. 1414, doi. 10.3390/molecules27041414

By:

Pereira Moreira, Bernardo;
Weber, Michael H. W.;
Haeberlein, Simone;
Mokosch, Annika S.;
Spengler, Bernhard;
Grevelding, Christoph G.;
Falcone, Franco H.

Publication type:

Article

Mitotic Poisons in Research and Medicine.

Published in:

Molecules, 2020, v. 25, n. 20, p. 4632, doi. 10.3390/molecules25204632

By:

Škubník, Jan;
Jurášek, Michal;
Ruml, Tomáš;
Rimpelová, Silvie;
Collina, Simona;
Miloso, Mariarosaria

Publication type:

Article

HSP70 colocalizes with PLK1 at the centrosome and disturbs spindle dynamics in cells arrested in mitosis by arsenic trioxide.

Published in:

Archives of Toxicology, 2014, v. 88, n. 9, p. 1711, doi. 10.1007/s00204-014-1222-x

By:

Chen, Yu-Ju;
Lai, Kuo-Chu;
Kuo, Hsiao-Hui;
Chow, Lu-Ping;
Yih, Ling-Huei;
Lee, Te-Chang

Publication type:

Article

Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes.

Published in:

Briefings in Bioinformatics, 2013, v. 14, n. 3, p. 344, doi. 10.1093/bib/bbs041

By:

Liu, Zexian;
Ren, Jian;
Cao, Jun;
He, Jiang;
Yao, Xuebiao;
Jin, Changjiang;
Xue, Yu

Publication type:

Article

A PLK4 mutation causing azoospermia in a man with Sertoli cell-only syndrome.

Published in:

Andrology, 2016, v. 4, n. 1, p. 75, doi. 10.1111/andr.12113

By:

Miyamoto, T.;
Bando, Y.;
Koh, E.;
Tsujimura, A.;
Miyagawa, Y.;
Iijima, M.;
Namiki, M.;
Shiina, M.;
Ogata, K.;
Matsumoto, N.;
Sengoku, K.

Publication type:

Article

PLK4 initiates crosstalk between cell cycle, cell proliferation and macrophages infiltration in gliomas.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.1055371

By:

Xiaoyang Zhang;
Zesheng Li;
Cheng Wei;
Lin Luo;
Shenghui Li;
Junhu Zhou;
Hao Liang;
Ying Li;
Lei Han

Publication type:

Article

PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2.

Published in:

Nature Cell Biology, 2015, v. 17, n. 8, p. 1024, doi. 10.1038/ncb3204

By:

Hanafusa, Hiroshi;
Kedashiro, Shin;
Tezuka, Motohiro;
Funatsu, Motoki;
Usami, Satoshi;
Toyoshima, Fumiko;
Matsumoto, Kunihiro

Publication type:

Article

Cardiac glycosides block cancer growth through HIF-1α- and NF-κB-mediated Plk1.

Published in:

Carcinogenesis, 2013, v. 34, n. 8, p. 1870, doi. 10.1093/carcin/bgt136

By:

Xie, Chuan-Ming;
Liu, Xiao-Yu;
Yu, Sidney;
Cheng, Christopher H.K.

Publication type:

Article

Integrated analysis of CRLF2 signaling in acute lymphoblastic leukemia identifies Polo-like kinase 1 as a potential therapeutic target.

Published in:

Leukemia & Lymphoma, 2015, v. 56, n. 5, p. 1524, doi. 10.3109/10428194.2014.963076

By:

Huang, Tai-Chung;
Cutler, Jevon;
Bharne, Shubhada;
Zhong, Jun;
Weinstock, David;
Tyner, Jeffrey;
Gojo, Ivana;
Civin, Curt;
Pandey, Akhilesh

Publication type:

Article

Polo-like kinase-1 immunoreactivity is associated with metastases in cutaneous melanoma.

Published in:

Journal of Cutaneous Pathology, 2017, v. 44, n. 10, p. 819, doi. 10.1111/cup.12985

By:

Kaczorowski, Maciej;
Borowiec, Tomasz;
Donizy, Piotr;
Pagacz, Konrad;
Fendler, Wojciech;
Lipinski, Artur;
Halon, Agnieszka;
Matkowski, Rafal

Publication type:

Article

An enzoinformatics study targeting polo-like kinases-1 enzyme: Comparative assessment of anticancer potential of compounds isolated from leaves of Ageratum houstonianum.

Published in:

Pharmacognosy Magazine, 2014, v. 10, n. 37S, p. S14, doi. 10.4103/0973-1296.127333

By:

Danish Rizvi, Syed Mohd.;
Shakil, Shazi;
Zeeshan, Mohd.;
Sajid Khan, Mohd.;
Shaikh, Sibhghatulla;
Biswas, Deboshree;
Ahmad, Adnan;
Amjad Kamal, Mohammad

Publication type:

Article

A randomised phase II trial of the Polo-like kinase inhibitor BI 2536 in chemo-naïve patients with unresectable exocrine adenocarcinoma of the pancreas - a study within the Central European Society Anticancer Drug Research (CESAR) collaborative network

Published in:

British Journal of Cancer, 2012, v. 107, n. 2, p. 280, doi. 10.1038/bjc.2012.257

By:

Mross, K;
Dittrich, C;
Aulitzky, W E;
Strumberg, D;
Schutte, J;
Schmid, R M;
Hollerbach, S;
Merger, M;
Munzert, G;
Fleischer, F;
Scheulen, M E

Publication type:

Article

Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.

Published in:

2016

By:

Amani, Vladimir;
Prince, Eric W.;
Alimova, Irina;
Balakrishnan, Ilango;
Birks, Diane;
Donson, Andrew M.;
Harris, Peter;
Levy, Jean M. Mulcahy;
Handler, Michael;
Foreman, Nicholas K.;
Venkataraman, Sujatha;
Vibhakar, Rajeev

Publication type:

journal article

Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.

Published in:

2016

By:

Zurnic, Irena;
Hütter, Sylvia;
Rzeha, Ute;
Helbig, Roger;
Stanke, Nicole;
Reh, Juliane;
Müllers, Erik;
Hamann, Martin V.;
Kern, Tobias;
Gerresheim, Gesche K.;
Lindel, Fabian;
Serrao, Erik;
Lesbats, Paul;
Engelman, Alan N.;
Cherepanov, Peter;
Lindemann, Dirk

Publication type:

Correction Notice

P53 suppresses SENP3 phosphorylation to mediate G2 checkpoint.

Published in:

Cell Discovery, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41421-020-0154-2

By:

Wang, Yang;
Tian, Jing;
Huang, Chao;
Ma, Jiao;
Hu, Gaolei;
Chen, Yalan;
Wang, Tianshi;
Cai, Rong;
Zuo, Yong;
Tan, Hongsheng;
Fan, Qiuju;
Dong, Baijun;
Xue, Wei;
Yi, Jing;
Chen, Guoqiang;
Tu, Jun;
Cheng, Jinke

Publication type:

Article

Generation of an inducible system to express polo-like kinase, Cdc5 as TAP fusion protein during meiosis in Saccharomyces cerevisiae.

Published in:

3 Biotech, 2016, v. 6, n. 2, p. 1, doi. 10.1007/s13205-016-0503-x

By:

Vaid, Rajni;
Dev, Kamal;
Lichten, Michael;
Sourirajan, Anuradha

Publication type:

Article

Polo-like kinase 3 is associated with poor prognosis and regulates proliferation and metastasis in prostate cancer.

Published in:

Cancer Management & Research, 2019, v. 11, p. 1517, doi. 10.2147/CMAR.S176762

By:

Lin, Chunhao;
Bai, Shoumin;
Du, Tao;
Lai, Yiming;
Chen, Xianju;
Peng, Shengmeng;
Ma, Xiaoming;
Wu, Wanhua;
Guo, Zhenghui;
Huang, Hai

Publication type:

Article

Anticancer activity of a novel small molecule tubulin inhibitor STK899704.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173311

By:

Sakchaisri, Krisada;
Kim, Sun-Ok;
Hwang, Joonsung;
Soung, Nak Kyun;
Lee, Kyung Ho;
Choi, Tae Woong;
Lee, Yongjun;
Park, Chan-Mi;
Thimmegowda, Naraganahalli R.;
Lee, Phil Young;
Shwetha, Bettaswamigowda;
Srinivasrao, Ganipisetti;
Pham, Thi Thu Huong;
Jang, Jae-Hyuk;
Yum, Hye-Won;
Surh, Young-Joon;
Lee, Kyung S.;
Park, Hwangseo;
Kim, Seung Jun;
Kwon, Yong Tae

Publication type:

Article

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150878

By:

Goetz, Jillian J.;
Laboissonniere, Lauren A.;
Wester, Andrea K.;
Lynch, Madison R.;
Trimarchi, Jeffrey M.

Publication type:

Article

The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0150225

By:

Lasek, Amber L.;
McPherson, Brittany M.;
Trueman, Natalie G.;
Burkard, Mark E.

Publication type:

Article

Increased Expression of Phosphorylated Polo-Like Kinase 1 and Histone in Bypass Vein Graft and Coronary Arteries following Angioplasty.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147937

By:

Sur, Swastika;
Swier, Vicki J.;
Radwan, Mohamed M.;
Agrawal, Devendra K.

Publication type:

Article

A Comprehensive Review of Protein Biomarkers for Invasive Lung Cancer.

Published in:

Current Oncology, 2024, v. 31, n. 9, p. 4818, doi. 10.3390/curroncol31090360

By:

Mezentsev, Alexandre;
Durymanov, Mikhail;
Makarov, Vladimir A.

Publication type:

Article

Evaluation of Polo-like kinase 1 as a potential therapeutic target in Merkel cell carcinoma.

Published in:

Head & Neck, 2016, v. 38, p. E1918, doi. 10.1002/hed.24349

By:

Kadletz, Lorenz;
Bigenzahn, Johannes;
Thurnher, Dietmar;
Stanisz, Isabella;
Erovic, Boban M.;
Schneider, Sven;
Schmid, Rainer;
Seemann, Rudolf;
Birner, Peter;
Heiduschka, Gregor

Publication type:

Article

QSAR, molecular docking, design, and pharmacokinetic analysis of 2-(4-fluorophenyl) imidazol-5-ones as anti-breast cancer drug compounds against MCF-7 cell line.

Published in:

Journal of Bioenergetics & Biomembranes, 2020, v. 52, n. 6, p. 475, doi. 10.1007/s10863-020-09858-0

By:

Lawal, Hadiza Abdulrahman;
Uzairu, Adamu;
Uba, Sani

Publication type:

Article

Developmental role of plk4 in Xenopus laevis and Danio rerio: implications for Seckel Syndrome.

Published in:

Biochemistry & Cell Biology, 2015, v. 93, n. 4, p. 396, doi. 10.1139/bcb-2015-0003

By:

Rapchak, Candace Elaine;
Patel, Neeraj;
Hudson, John;
Crawford, Michael

Publication type:

Article

Opposing Action of Nuclear Factor κB and Polo-like Kinases Determines a Homeostatic End Point for Excitatory Synaptic Adaptation.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 42, p. 16490, doi. 10.1523/JNEUROSCI.2131-13.2013

By:

Mihalas, Anca B.;
Araki, Yoichi;
Huganir, Richard L.;
Meffert, Mollie K.

Publication type:

Article

Designed inhibitor for nuclear localization signal of polo-like kinase 1 induces mitotic arrest.

Published in:

Chemical Biology & Drug Design, 2017, v. 89, n. 5, p. 732, doi. 10.1111/cbdd.12896

By:

Chen, Fangjin;
Zhuo, Xiaolong;
Qin, Tan;
Guo, Xiao;
Zhang, Chuanmao;
Lai, Luhua

Publication type:

Article

Polo-like kinase 3 is associated with improved overall survival in cholangiocarcinoma.

Published in:

Liver International, 2015, v. 35, n. 11, p. 2448, doi. 10.1111/liv.12839

By:

Juntermanns, Benjamin;
Sydor, Svenja;
Kaiser, Gernot M.;
Jaradat, Derar;
Mertens, Joachim C.;
Sotiropoulos, Georgios C.;
Swoboda, Sandra;
Neuhaus, Jan P.;
Meng, Wei;
Mathé, Zoltan;
Baba, Hideo A.;
Canbay, Ali;
Paul, Andreas;
Fingas, Christian D.

Publication type:

Article

Monitoring of changes in lipid profiles during PLK1 knockdown in cancer cells using DESI MS.

Published in:

Analytical & Bioanalytical Chemistry, 2016, v. 408, n. 20, p. 5623, doi. 10.1007/s00216-016-9665-y

By:

Jayashree, Balasubramanyam;
Srimany, Amitava;
Jayaraman, Srinidhi;
Bhutra, Anjali;
Janakiraman, Narayanan;
Chitipothu, Srujana;
Krishnakumar, Subramanian;
Baddireddi, Lakshmi;
Elchuri, Sailaja;
Pradeep, Thalappil

Publication type:

Article

PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer.

Published in:

Molecular Biology Reports, 2014, v. 41, n. 10, p. 6635, doi. 10.1007/s11033-014-3546-2

By:

Shinmura, Kazuya;
Kurabe, Nobuya;
Goto, Masanori;
Yamada, Hidetaka;
Natsume, Hiroko;
Konno, Hiroyuki;
Sugimura, Haruhiko

Publication type:

Article

Antiproliferative in vitro effects of BI 2536-mediated PLK1 inhibition on cervical adenocarcinoma cells.

Published in:

Clinical & Experimental Medicine, 2013, v. 13, n. 1, p. 75, doi. 10.1007/s10238-011-0166-1

By:

Pezuk, Julia;
Brassesco, María;
Oliveira, Jaqueline;
Morales, Andressa;
Montaldi, Ana;
Sakamoto-Hojo, Elza;
Scrideli, Carlos;
Tone, Luiz

Publication type:

Article

Comprehensive and Integrative Analysis Reveals the Diagnostic, Clinicopathological and Prognostic Significance of Polo-Like Kinase 1 in Hepatocellular Carcinoma.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 47, n. 3, p. 925, doi. 10.1159/000490135

By:

Lin, Peng;
Wen, Dong-yue;
Dang, Yi-wu;
He, Yun;
Yang, Hong;
Chen, Gang

Publication type:

Article

Tazarotene-induced gene 1 interacts with Polo-like kinase 2 and inhibits cell proliferation in HCT116 colorectal cancer cells.

Published in:

Cell Biology International, 2021, v. 45, n. 11, p. 2347, doi. 10.1002/cbin.11681

By:

Chun-Hua Wang;
Tzung-Ju Lu;
Lu-Kai Wang;
Chang-Chieh Wu;
Mao-Liang Chen;
Chan-Yen Kuo;
Rong-Yaun Shyu;
Fu-Ming Tsai

Publication type:

Article

Augmented expression of Polo-like kinase 1 is a strong predictor of shorter cancer-specific overall survival in early stage breast cancer at 15-year follow-up.

Published in:

Oncology Letters, 2016, v. 12, n. 3, p. 1667, doi. 10.3892/ol.2016.4890

By:

DONIZY, PIOTR;
HALON, AGNIESZKA;
SUROWIAK, PAWEL;
KACZOROWSKI, MACIEJ;
KOZYRA, CYPRIAN;
MATKOWSKI, RAFAL

Publication type:

Article

Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell lines.

Published in:

Clinical & Experimental Ophthalmology, 2017, v. 45, n. 3, p. 288, doi. 10.1111/ceo.12838

By:

Schwermer, Melanie;
Dreesmann, Sabine;
Eggert, Angelika;
Althoff, Kristina;
Steenpass, Laura;
Schramm, Alexander;
Schulte, Johannes H;
Temming, Petra

Publication type:

Article

Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-12619-2

By:

Park, Jung-Eun;
Zhang, Liang;
Bang, Jeong Kyu;
Andresson, Thorkell;
DiMaio, Frank;
Lee, Kyung S.

Publication type:

Article

Genetic depletion of Polo-like kinase 1 leads to embryonic lethality due to mitotic aberrancies.

Published in:

BioEssays, 2016, v. 38, p. S96, doi. 10.1002/bies.201670908

By:

Wachowicz, Paulina;
Fernández‐Miranda, Gonzalo;
Marugán, Carlos;
Escobar, Beatriz;
Cárcer, Guillermo

Publication type:

Article