Works matching DE "POLO-like kinases"

Results: 169

Polo-like kinase 3 is associated with improved overall survival in cholangiocarcinoma.

Published in:

Liver International, 2015, v. 35, n. 11, p. 2448, doi. 10.1111/liv.12839

By:

Juntermanns, Benjamin;
Sydor, Svenja;
Kaiser, Gernot M.;
Jaradat, Derar;
Mertens, Joachim C.;
Sotiropoulos, Georgios C.;
Swoboda, Sandra;
Neuhaus, Jan P.;
Meng, Wei;
Mathé, Zoltan;
Baba, Hideo A.;
Canbay, Ali;
Paul, Andreas;
Fingas, Christian D.

Publication type:

Article

Optimizing the Size of Micellar Nanoparticles for Efficient siRNA Delivery.

Published in:

Advanced Functional Materials, 2015, v. 25, n. 30, p. 4778, doi. 10.1002/adfm.201501548

By:

Liang, Shi;
Yang, Xian‐Zhu;
Du, Xiao‐Jiao;
Wang, Hong‐Xia;
Li, Hong‐Jun;
Liu, Wei‐Wei;
Yao, Yan‐Dan;
Zhu, Yan‐Hua;
Ma, Yin‐Chu;
Wang, Jun;
Song, Er‐Wei

Publication type:

Article

High levels of polo-like kinase 1 and phosphorylated translationally controlled tumor protein indicate poor prognosis in neuroblastomas.

Published in:

Journal of Neuro-Oncology, 2015, v. 125, n. 1, p. 103, doi. 10.1007/s11060-015-1900-4

By:

Ramani, Pramila;
Nash, Rachel;
Sowa-Avugrah, Emile;
Rogers, Chris

Publication type:

Article

Multi-omics insights into the roles of CCNB1, PLK1, and HPSE in breast cancer progression: implications for prognosis and immunotherapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02282-z

By:

Su, Qisheng;
Fang, Leiming;
Li, Chaofan;
Yue, Liang;
Yun, Zhimin;
Zhang, Huiqiang;
Liu, Qi;
Ma, Ruilin;
Zhong, Pengfei;
Liu, He;
Lou, Zhangrong;
Chen, Zhi;
Tan, Yingxia;
Hao, Xiaopeng;
Wu, Chengjun

Publication type:

Article

Multi-omics insights into the roles of CCNB1, PLK1, and HPSE in breast cancer progression: implications for prognosis and immunotherapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02282-z

By:

Su, Qisheng;
Fang, Leiming;
Li, Chaofan;
Yue, Liang;
Yun, Zhimin;
Zhang, Huiqiang;
Liu, Qi;
Ma, Ruilin;
Zhong, Pengfei;
Liu, He;
Lou, Zhangrong;
Chen, Zhi;
Tan, Yingxia;
Hao, Xiaopeng;
Wu, Chengjun

Publication type:

Article

miR-23a suppresses pancreatic cancer cell progression by inhibiting PLK-1 expression.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 105, doi. 10.3892/mmr.2018.8941

By:

Chen, Bin;
Zhu, Akao;
Tian, Lei;
Xin, Ying;
Liu, Xinchun;
Peng, Yunpeng;
Zhang, Jingjing;
Miao, Yi;
Wei, Jishu

Publication type:

Article

Polo-like kinase 3 inhibits osteosarcoma cell proliferation and tumorigenesis via cooperative interaction with p21.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 5, p. 6789, doi. 10.3892/mmr.2015.4304

By:

HONGLIN LV;
GUANGTING GAO;
LINLIN ZHANG;
YUJIE SUN

Publication type:

Article

Comprehensive Characterization of Immune Cell Infiltration Characteristics and Drug Sensitivity Analysis in Inflammatory Breast Cancer Based on Bioinformatic Strategy.

Published in:

Biochemical Genetics, 2024, v. 62, n. 2, p. 1021, doi. 10.1007/s10528-023-10460-3

By:

Zhang, Zhengguang;
Wu, Haitao;
Shen, Cunsi;
Zhou, Fuqiong

Publication type:

Article

A randomised phase II trial of the Polo-like kinase inhibitor BI 2536 in chemo-naïve patients with unresectable exocrine adenocarcinoma of the pancreas - a study within the Central European Society Anticancer Drug Research (CESAR) collaborative network

Published in:

British Journal of Cancer, 2012, v. 107, n. 2, p. 280, doi. 10.1038/bjc.2012.257

By:

Mross, K;
Dittrich, C;
Aulitzky, W E;
Strumberg, D;
Schutte, J;
Schmid, R M;
Hollerbach, S;
Merger, M;
Munzert, G;
Fleischer, F;
Scheulen, M E

Publication type:

Article

Plk1 in Asthma: Ready for Primetime?

Published in:

2022

By:

Kit Chung Tam, John;
Thai Tran

Publication type:

Editorial

Selective Degradation of Polo‐like Kinase 1 by a Hydrophobically Tagged Inhibitor of the Polo‐Box Domain.

Published in:

Angewandte Chemie, 2018, v. 130, n. 52, p. 17289, doi. 10.1002/ange.201809640

By:

Rubner, Stefan;
Scharow, Andrej;
Schubert, Sabine;
Berg, Thorsten

Publication type:

Article

Downregulation of microRNA-100 correlates with tumor progression and poor prognosis in hepatocellular carcinoma.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 383, n. 1/2, p. 49, doi. 10.1007/s11010-013-1753-0

By:

Chen, Ping;
Zhao, Xia;
Ma, Liang

Publication type:

Article

Antiproliferative in vitro effects of BI 2536-mediated PLK1 inhibition on cervical adenocarcinoma cells.

Published in:

Clinical & Experimental Medicine, 2013, v. 13, n. 1, p. 75, doi. 10.1007/s10238-011-0166-1

By:

Pezuk, Julia;
Brassesco, María;
Oliveira, Jaqueline;
Morales, Andressa;
Montaldi, Ana;
Sakamoto-Hojo, Elza;
Scrideli, Carlos;
Tone, Luiz

Publication type:

Article

Tazarotene-induced gene 1 interacts with Polo-like kinase 2 and inhibits cell proliferation in HCT116 colorectal cancer cells.

Published in:

Cell Biology International, 2021, v. 45, n. 11, p. 2347, doi. 10.1002/cbin.11681

By:

Chun-Hua Wang;
Tzung-Ju Lu;
Lu-Kai Wang;
Chang-Chieh Wu;
Mao-Liang Chen;
Chan-Yen Kuo;
Rong-Yaun Shyu;
Fu-Ming Tsai

Publication type:

Article

P53 suppresses SENP3 phosphorylation to mediate G2 checkpoint.

Published in:

Cell Discovery, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41421-020-0154-2

By:

Wang, Yang;
Tian, Jing;
Huang, Chao;
Ma, Jiao;
Hu, Gaolei;
Chen, Yalan;
Wang, Tianshi;
Cai, Rong;
Zuo, Yong;
Tan, Hongsheng;
Fan, Qiuju;
Dong, Baijun;
Xue, Wei;
Yi, Jing;
Chen, Guoqiang;
Tu, Jun;
Cheng, Jinke

Publication type:

Article

联合入路翻页式腹腔镜辅助右半结肠癌根治术与开腹根治术术后近期效果比较.

Published in:

Progress in Modern Biomedicine, 2022, v. 22, n. 3, p. 548, doi. 10.13241/j.cnki.pmb.2022.03.031

By:

吴金东;
江晓晖;
朱汉达;
张小磊;
李国兴

Publication type:

Article

A PLK4 mutation causing azoospermia in a man with Sertoli cell-only syndrome.

Published in:

Andrology, 2016, v. 4, n. 1, p. 75, doi. 10.1111/andr.12113

By:

Miyamoto, T.;
Bando, Y.;
Koh, E.;
Tsujimura, A.;
Miyagawa, Y.;
Iijima, M.;
Namiki, M.;
Shiina, M.;
Ogata, K.;
Matsumoto, N.;
Sengoku, K.

Publication type:

Article

Role of Polo-like Kinases Plk1 and Plk4 in the Initiation of Centriole Duplication—Impact on Cancer.

Published in:

Cells (2073-4409), 2022, v. 11, n. 5, p. 786, doi. 10.3390/cells11050786

By:

Hoffmann, Ingrid

Publication type:

Article

A Novel Hyperactive Nud1 Mitotic Exit Network Scaffold Causes Spindle Position Checkpoint Bypass in Budding Yeast.

Published in:

Cells (2073-4409), 2022, v. 11, n. 1, p. 46, doi. 10.3390/cells11010046

By:

Vannini, Michael;
Mingione, Victoria R.;
Meyer, Ashleigh;
Sniffen, Courtney;
Whalen, Jenna;
Seshan, Anupama

Publication type:

Article

Modelling the Functions of Polo-Like Kinases in Mice and Their Applications as Cancer Targets with a Special Focus on Ovarian Cancer.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1176, doi. 10.3390/cells10051176

By:

Kressin, Monika;
Fietz, Daniela;
Becker, Sven;
Strebhardt, Klaus;
Schnütgen, Frank

Publication type:

Article

Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6.

Published in:

Cells (2073-4409), 2020, v. 9, n. 6, p. 1506, doi. 10.3390/cells9061506

By:

Aquino Perez, Cecilia;
Palek, Matous;
Stolarova, Lenka;
von Morgen, Patrick;
Macurek, Libor

Publication type:

Article

Polo-Like Kinase 4's Critical Role in Cancer Development and Strategies for Plk4-Targeted Therapy.

Published in:

Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.587554

By:

Zhang, Xiaoyang;
Wei, Cheng;
Liang, Hao;
Han, Lei

Publication type:

Article

Research Progress on Targets and Selective Inhibitors of Polo-like Kinase-1 (PLK-1).

Published in:

Medicinal Plant, 2024, v. 15, n. 1, p. 51, doi. 10.19600/j.cnki.issn2152-3924.2024.01.013

By:

Xin WANG;
Qin ZENG;
Guangying DU

Publication type:

Article

Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26828-1

By:

Menon, Debashish U.;
Kirsanov, Oleksandr;
Geyer, Christopher B.;
Magnuson, Terry

Publication type:

Article

The RAD51 recombinase protects mitotic chromatin in human cells.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25643-y

By:

Wassing, Isabel E.;
Graham, Emily;
Saayman, Xanita;
Rampazzo, Lucia;
Ralf, Christine;
Bassett, Andrew;
Esashi, Fumiko

Publication type:

Article

RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23186-w

By:

Carr, Ryan M.;
Vorobyev, Denis;
Lasho, Terra;
Marks, David L.;
Tolosa, Ezequiel J.;
Vedder, Alexis;
Almada, Luciana L.;
Yurcheko, Andrey;
Padioleau, Ismael;
Alver, Bonnie;
Coltro, Giacomo;
Binder, Moritz;
Safgren, Stephanie L.;
Horn, Isaac;
You, Xiaona;
Solary, Eric;
Balasis, Maria E.;
Berger, Kurt;
Hiebert, James;
Witzig, Thomas

Publication type:

Article

Targeting Echinococcus multilocularis Stem Cells by Inhibition of the Polo-Like Kinase EmPlk1.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 6, p. 1, doi. 10.1371/journal.pntd.0002870

By:

Schubert, Andreas;
Koziol, Uriel;
Cailliau, Katia;
Vanderstraete, Mathieu;
Dissous, Colette;
Brehm, Klaus

Publication type:

Article

Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis.

Published in:

Bioscience Reports, 2014, v. 34, n. 3, p. 257, doi. 10.1042/BSR20140051

By:

DOUGLAS, Pauline;
Ruiqiong YE;
TRINKLE-MULCAHY, Laura;
NEAL, Jessica A.;
De WEVER, Veerle;
MORRICE, Nick A.;
MEEK, Katheryn;
LEES-MILLER, Susan P.

Publication type:

Article

A Comprehensive Review of Protein Biomarkers for Invasive Lung Cancer.

Published in:

Current Oncology, 2024, v. 31, n. 9, p. 4818, doi. 10.3390/curroncol31090360

By:

Mezentsev, Alexandre;
Durymanov, Mikhail;
Makarov, Vladimir A.

Publication type:

Article

Mitotic kinases are emerging therapeutic targets against metastatic breast cancer.

Published in:

Cell Division, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13008-024-00125-x

By:

Aquino-Acevedo, Alexandra N.;
Orengo-Orengo, Joel A.;
Cruz-Robles, Melanie E.;
Saavedra, Harold I.

Publication type:

Article

In-silico screening of cancer associated mutation on PLK1 protein and its structural consequences.

Published in:

Journal of Molecular Modeling, 2013, v. 19, n. 12, p. 5587, doi. 10.1007/s00894-013-2044-0

By:

Kamaraj, Balu;
Rajendran, Vidya;
Sethumadhavan, Rao;
Purohit, Rituraj

Publication type:

Article

PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas.

Published in:

2018

By:

Yuan Ren;
Chengfeng Bi;
Xiaohong Zhao;
Tint Lwin;
Cheng Wang;
Ji Yuan;
Silva, Ariosto S.;
Shah, Bijal D.;
Fang, Bin;
Tao Li;
Koomen, John M.;
Huijuan Jiang;
Chavez, Julio C.;
Pham, Lan V.;
Sudalagunta, Praneeth R.;
Lixin Wan;
Xuefeng Wang;
Dalton, William S.;
Moscinski, Lynn C.;
Shain, Kenneth H.

Publication type:

journal article

PLK1: a promising and previously unexplored target in double-hit lymphoma.

Published in:

2018

By:

Hassan II, Quais N.;
Alinari, Lapo;
Byrd, John C.;
Hassan, Quais N 2nd

Publication type:

journal article

Phytochemical constituents, in-vitro anticancer activity and computational studies of Cymbopogon schoenanthus.

Published in:

Natural Product Research, 2024, v. 38, n. 6, p. 1073, doi. 10.1080/14786419.2023.2208360

By:

Hago, Salma;
Lu, Tang;
Alzain, Abdulrahim A.;
Abdelgadir, Abdelgadir A.;
Yassin, Sitelbanat;
Ahmed, Elhadi M.;
Xu, Hanmei

Publication type:

Article

Polo-Like Kinase 4 (PLK4) Is Overexpressed in Central Nervous System Neuroblastoma (CNS-NB).

Published in:

Bioengineering (Basel), 2018, v. 5, n. 4, p. 1, doi. 10.3390/bioengineering5040096

By:

Bailey, Anders W.;
Suri, Amreena;
Chou, Pauline M.;
Pundy, Tatiana;
Gadd, Samantha;
Raimondi, Stacey L.;
Tomita, Tadanori;
Sredni, Simone Treiger

Publication type:

Article

GSK461364A, a Polo-Like Kinase-1 Inhibitor Encapsulated in Polymeric Nanoparticles for the Treatment of Glioblastoma Multiforme (GBM).

Published in:

Bioengineering (Basel), 2018, v. 5, n. 4, p. 1, doi. 10.3390/bioengineering5040083

By:

Velpurisiva, Praveena;
Piel, Brandon P.;
Lepine, Jack;
Rai, Prakash

Publication type:

Article

Kinesin-13, a Motor Protein, is Regulated by Polo-like Kinase in Giardia lamblia.

Published in:

Korean Journal of Parasitology, 2022, v. 60, n. 3, p. 163, doi. 10.3347/kjp.2022.60.3.163

By:

Eun-Ah Park;
Juri Kim;
Mee Young Shin;
Soon-Jung Park

Publication type:

Article

Generation of an inducible system to express polo-like kinase, Cdc5 as TAP fusion protein during meiosis in Saccharomyces cerevisiae.

Published in:

3 Biotech, 2016, v. 6, n. 2, p. 1, doi. 10.1007/s13205-016-0503-x

By:

Vaid, Rajni;
Dev, Kamal;
Lichten, Michael;
Sourirajan, Anuradha

Publication type:

Article

Understanding the Polo Kinase machine.

Published in:

Oncogene, 2015, v. 34, n. 37, p. 4799, doi. 10.1038/onc.2014.451

By:

Archambault, V;
Lépine, G;
Kachaner, D

Publication type:

Article

A novel role for Plk4 in regulating cell spreading and motility.

Published in:

Oncogene, 2015, v. 34, n. 26, p. 3441, doi. 10.1038/onc.2014.275

By:

Rosario, C O;
Kazazian, K;
Zih, F S W;
Brashavitskaya, O;
Haffani, Y;
Xu, R S Z;
George, A;
Dennis, J W;
Swallow, C J

Publication type:

Article

Testis- and ovary-expressed polo-like kinase transcripts and gene duplications affect male fertility when expressed in the Drosophila melanogaster germline.

Published in:

G3: Genes | Genomes | Genetics, 2025, v. 15, n. 1, p. 1, doi. 10.1093/g3journal/jkae273

By:

Najera, Paola;
Dratler, Olivia A;
Mai, Alexander B;
Elizarraras, Miguel;
Vanchinathan, Rahul;
Gonzales, Christopher A;
Meisel, Richard P

Publication type:

Article

Regulation of intestinal stem cell activity by a mitotic cell cycle regulator Polo in Drosophila.

Published in:

G3: Genes | Genomes | Genetics, 2023, v. 13, n. 6, p. 1, doi. 10.1093/g3journal/jkad084

By:

Ying Zhang;
Rongbing Chen;
Liyuan Gong;
Wuren Huang;
Ping Li;
Zongzhao Zhai;
Erjun Ling

Publication type:

Article

Integrated analysis of CRLF2 signaling in acute lymphoblastic leukemia identifies Polo-like kinase 1 as a potential therapeutic target.

Published in:

Leukemia & Lymphoma, 2015, v. 56, n. 5, p. 1524, doi. 10.3109/10428194.2014.963076

By:

Huang, Tai-Chung;
Cutler, Jevon;
Bharne, Shubhada;
Zhong, Jun;
Weinstock, David;
Tyner, Jeffrey;
Gojo, Ivana;
Civin, Curt;
Pandey, Akhilesh

Publication type:

Article

The Plk1 inhibitor BI 2536 in patients with refractory or relapsed non-Hodgkin lymphoma: a phase I, open-label, single dose-escalation study.

Published in:

Leukemia & Lymphoma, 2013, v. 54, n. 4, p. 708, doi. 10.3109/10428194.2012.729833

By:

Vose, Julie M.;
Friedberg, Jonathan W.;
Waller, Edmund K.;
Cheson, Bruce D.;
Juvvigunta, Vasthala;
Fritsch, Holger;
Petit, Claude;
Munzert, Gerd;
Younes, Anas

Publication type:

Article

Polo-Like Kinase 1: A Novel Target for the Treatment of Therapy-Resistant Mantle Cell Lymphoma.

Published in:

Lymphoma (2090309X), 2013, p. 1, doi. 10.1155/2013/782903

By:

Ahrens, Adam K.;
Chaturvedi, Nagendra K.;
Shukla, Ashima;
Nordgren, Tara M.;
Hegde, Ganapati V.;
Vose, Julie M.;
Joshi, Shantaram S.

Publication type:

Article

Anticancer activity of a novel small molecule tubulin inhibitor STK899704.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0173311

By:

Sakchaisri, Krisada;
Kim, Sun-Ok;
Hwang, Joonsung;
Soung, Nak Kyun;
Lee, Kyung Ho;
Choi, Tae Woong;
Lee, Yongjun;
Park, Chan-Mi;
Thimmegowda, Naraganahalli R.;
Lee, Phil Young;
Shwetha, Bettaswamigowda;
Srinivasrao, Ganipisetti;
Pham, Thi Thu Huong;
Jang, Jae-Hyuk;
Yum, Hye-Won;
Surh, Young-Joon;
Lee, Kyung S.;
Park, Hwangseo;
Kim, Seung Jun;
Kwon, Yong Tae

Publication type:

Article

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150878

By:

Goetz, Jillian J.;
Laboissonniere, Lauren A.;
Wester, Andrea K.;
Lynch, Madison R.;
Trimarchi, Jeffrey M.

Publication type:

Article

The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic Complementation.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0150225

By:

Lasek, Amber L.;
McPherson, Brittany M.;
Trueman, Natalie G.;
Burkard, Mark E.

Publication type:

Article

Increased Expression of Phosphorylated Polo-Like Kinase 1 and Histone in Bypass Vein Graft and Coronary Arteries following Angioplasty.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147937

By:

Sur, Swastika;
Swier, Vicki J.;
Radwan, Mohamed M.;
Agrawal, Devendra K.

Publication type:

Article

QSAR, molecular docking, design, and pharmacokinetic analysis of 2-(4-fluorophenyl) imidazol-5-ones as anti-breast cancer drug compounds against MCF-7 cell line.

Published in:

Journal of Bioenergetics & Biomembranes, 2020, v. 52, n. 6, p. 475, doi. 10.1007/s10863-020-09858-0

By:

Lawal, Hadiza Abdulrahman;
Uzairu, Adamu;
Uba, Sani

Publication type:

Article