Works about PHOSPHORYLATION

Results: 5000

SR protein kinases promote splicing of nonconsensus introns.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 8, p. 611, doi. 10.1038/nsmb.3057

By:

Lipp, Jesse J;
Marvin, Michael C;
Shokat, Kevan M;
Guthrie, Christine

Publication type:

Article

CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 396, doi. 10.1038/nsmb.3000

By:

Laitem, Clélia;
Zaborowska, Justyna;
Isa, Nur F;
Kufs, Johann;
Dienstbier, Martin;
Murphy, Shona

Publication type:

Article

A little less leads to lots more.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 5, p. 350, doi. 10.1038/nsmb.3023

By:

Warner, Jonathan R

Publication type:

Article

Crystal structure of a phosphorylation-coupled vitamin C transporter.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 238, doi. 10.1038/nsmb.2975

By:

Luo, Ping;
Yu, Xinzhe;
Wang, Weiguang;
Fan, Shilong;
Li, Xiaochun;
Wang, Jiawei

Publication type:

Article

Bringing phosphorylation into the fold.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 2, p. 108, doi. 10.1038/nsmb.2972

By:

Dellisanti, Cosma

Publication type:

Article

An enzyme cofactor with a split personality.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 2, p. 101, doi. 10.1038/nsmb.2968

By:

Mittermaier, Anthony

Publication type:

Article

Uncovering global SUMOylation signaling networks in a site-specific manner.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 10, p. 927, doi. 10.1038/nsmb.2890

By:

Hendriks, Ivo A;
D'Souza, Rochelle C J;
Yang, Bing;
Verlaan-de Vries, Matty;
Mann, Matthias;
Vertegaal, Alfred C O

Publication type:

Article

Kin28 regulates the transient association of Mediator with core promoters.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 449, doi. 10.1038/nsmb.2810

By:

Jeronimo, Célia;
Robert, François

Publication type:

Article

JAK-cytokine receptor recognition, unboxed.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 431, doi. 10.1038/nsmb.2824

By:

McNally, Randall;
Eck, Michael J

Publication type:

Article

In vitro membrane reconstitution of the T-cell receptor proximal signaling network.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 2, p. 133, doi. 10.1038/nsmb.2762

By:

Hui, Enfu;
Vale, Ronald D

Publication type:

Article

Grb-ing receptor activation by the tail.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 2, p. 113, doi. 10.1038/nsmb.2767

By:

Fearon, Abbie E;
Grose, Richard P

Publication type:

Article

Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 103, doi. 10.1038/nsmb.2737

By:

Lee, Cheng-Sheng;
Lee, Kihoon;
Legube, Gaëlle;
Haber, James E

Publication type:

Article

Multisite phosphorylation networks as signal processors for Cdk1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1415, doi. 10.1038/nsmb.2706

By:

Kõivomägi, Mardo;
Örd, Mihkel;
Iofik, Anna;
Valk, Ervin;
Venta, Rainis;
Faustova, Ilona;
Kivi, Rait;
Balog, Eva Rose M;
Rubin, Seth M;
Loog, Mart

Publication type:

Article

Cks confers specificity to phosphorylation-dependent CDK signaling pathways.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1407, doi. 10.1038/nsmb.2707

By:

McGrath, Denise A;
Balog, Eva Rose M;
Kõivomägi, Mardo;
Lucena, Rafael;
Mai, Michelle V;
Hirschi, Alexander;
Kellogg, Douglas R;
Loog, Mart;
Rubin, Seth M

Publication type:

Article

Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 982, doi. 10.1038/nsmb.2621

By:

Dou, Hao;
Buetow, Lori;
Sibbet, Gary J;
Cameron, Kenneth;
Huang, Danny T

Publication type:

Article

mTOR: restricted access.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 656, doi. 10.1038/nsmb.2610

By:

Larochelle, Stéphane

Publication type:

Article

Sequential primed kinases create a damage-responsive phosphodegron on Eco1.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 2, p. 194, doi. 10.1038/nsmb.2478

By:

Lyons, Nicholas A;
Fonslow, Bryan R;
Diedrich, Jolene K;
Yates, John R;
Morgan, David O

Publication type:

Article

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 11, p. 1108, doi. 10.1038/nsmb.2399

By:

Larochelle, Stéphane;
Amat, Ramon;
Glover-Cutter, Kira;
Sansó, Miriam;
Zhang, Chao;
Allen, Jasmina J;
Shokat, Kevan M;
Bentley, David L;
Fisher, Robert P

Publication type:

Article

H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 930, doi. 10.1038/nsmb.2356

By:

Mahajan, Kiran;
Fang, Bin;
Koomen, John M;
Mahajan, Nupam P

Publication type:

Article

Phosphorylation of histone H3 Ser10 establishes a hierarchy for subsequent intramolecular modification events.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 8, p. 819, doi. 10.1038/nsmb.2310

By:

Liokatis, Stamatios;
Stützer, Alexandra;
Elsässer, Simon J;
Theillet, Francois-Xavier;
Klingberg, Rebecca;
van Rossum, Barth;
Schwarzer, Dirk;
Allis, C David;
Fischle, Wolfgang;
Selenko, Philipp

Publication type:

Article

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 3, p. 283, doi. 10.1038/nsmb.2217

By:

Kim, Myoung Ok;
Kim, Sung-Hyun;
Cho, Yong-Yeon;
Nadas, Janos;
Jeong, Chul-Ho;
Yao, Ke;
Kim, Dong Joon;
Yu, Dong-Hoon;
Keum, Young-Sam;
Lee, Kun-Yeong;
Huang, Zunnan;
Bode, Ann M;
Dong, Zigang

Publication type:

Article

Phosphorylation-dependent activity of the deubiquitinase DUBA.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 171, doi. 10.1038/nsmb.2206

By:

Huang, Oscar W;
Ma, Xiaolei;
Yin, JianPing;
Flinders, Jeremy;
Maurer, Till;
Kayagaki, Nobuhiko;
Phung, Qui;
Bosanac, Ivan;
Arnott, David;
Dixit, Vishva M;
Hymowitz, Sarah G;
Starovasnik, Melissa A;
Cochran, Andrea G

Publication type:

Article

Cbl exposes its RING finger.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 131, doi. 10.1038/nsmb.2241

By:

Kales, Stephen C;
Ryan, Philip E;
Lipkowitz, Stanley

Publication type:

Article

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 2, p. 184, doi. 10.1038/nsmb.2231

By:

Dou, Hao;
Buetow, Lori;
Hock, Andreas;
Sibbet, Gary J;
Vousden, Karen H;
Huang, Danny T

Publication type:

Article

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 971, doi. 10.1038/nsmb.2099

By:

Ungureanu, Daniela;
Jinhua Wu;
Pekkala, Tuija;
Niranjan, Yashavanthi;
Young, Clifford;
Jensen, Ole N.;
Chong-Feng Xu;
Neubert, Thomas A.;
Skoda, Radek C.;
Hubbard, Stevan R.;
Silvennoinen, Olli

Publication type:

Article

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 984, doi. 10.1038/nsmb.2092

By:

Li-Zhi Mi;
Chafen Lu;
Zongli Li;
Nishida, Noritaka;
Walz, Thomas;
Springer, Timothy A.

Publication type:

Article

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 1015, doi. 10.1038/nsmb.2105

By:

Xuefeng Chen;
Hengyao Niu;
Woo-Hyun Chung;
Zhu Zhu;
Papusha, Alma;
Eun Yong Shim;
Sang Eun Lee;
Sung, Patrick;
Ira, Grzegorz

Publication type:

Article

SUMOylation regulates telomere length homeostasis by targeting Cdc13.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 8, p. 920, doi. 10.1038/nsmb.2100

By:

Hang, Lisa E.;
Xianpeng Liu;
Cheung, Iris;
Yan Yang;
Xiaolan Zhao

Publication type:

Article

Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 8, p. 956, doi. 10.1038/nsmb.2085

By:

Koch, Frederic;
Fenouil, Romain;
Gut, Marta;
Cauchy, Pierre;
Albert, Thomas K.;
Zacarias-Cabeza, Joaquin;
Spicuglia, Salvatore;
de la Chapelle, Albane Lamy;
Heidemann, Martin;
Hintermair, Corinna;
Eick, Dirk;
Gut, Ivo;
Ferrier, Pierre;
Andrau, Jean-Christophe

Publication type:

Article

Research highlights.

Published in:: Nature Structural & Molecular Biology, 2011, v. 18, n. 7, p. 747, doi. 10.1038/nsmb0711-747
Publication type:: Article

KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 7, p. 831, doi. 10.1038/nsmb.2077

By:

Goodarzi, Aaron A.;
Kurka, Thomas;
Jeggo, Penelope A.

Publication type:

Article

Recognition of the F&H motif by the Lowe syndrome protein OCRL.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 7, p. 789, doi. 10.1038/nsmb.2071

By:

Pirruccello, Michelle;
Swan, Laura E;
Folta-Stogniew, Ewa;
De Camilli, Pietro

Publication type:

Article

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 1, p. 42, doi. 10.1038/nsmb.1939

By:

Estève, Pierre-Olivier;
Yanqi Chang;
Samaranayake, Mala;
Upadhyay, Anup K;
Horton, John R;
Feehery, George R;
Xiaodong Cheng;
Pradhan, Sriharsa

Publication type:

Article

Understanding of the Hsp90 molecular chaperone reaches new heights.

Published in:

2010

By:

Vaughan, Cara K.;
Neckers, Len;
Piper, Peter W.

Publication type:

Proceeding

Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1195, doi. 10.1038/nsmb.1893

By:

Lunde, Bradley M.;
Reichow, Steve L.;
Minkyu Kim;
Hyunsuk Suh;
Leeper, Thomas C.;
Fan Yang;
Mutschler, Hannes;
Buratowski, Stephen;
Meinhart, Anton;
Varani, Gabriele

Publication type:

Article

Uniform transitions of the general RNA polymerase II transcription complex.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1272, doi. 10.1038/nsmb.1903

By:

Mayer, Andreas;
Lidschreiber, Michael;
Siebert, Matthias;
Leike, Kristin;
Söding, Johannes;
Cramer, Patrick

Publication type:

Article

Gene-specific RNA polymerase II phosphorylation and the CTD code.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1279, doi. 10.1038/nsmb.1913

By:

Hyunmin Kim;
Erickson, Benjamin;
Weifei Luo;
Seward, David;
Graber, Joel H.;
Pollock, David D.;
Megee, Paul C.;
Bentley, David L.

Publication type:

Article

Chemical-genomic dissection of the CTD code.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1154, doi. 10.1038/nsmb.1900

By:

Tietjen, Joshua R;
Zhang, David W;
Rodríguez-Molina, Juan B;
White, Brent E;
Akhtar, Md Sohail;
Heidemann, Martin;
Li, Xin;
Chapman, Rob D;
Shokat, Kevan;
Keles, Sündüz;
Eick, Dirk;
Ansari, Aseem Z

Publication type:

Article

An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 9, p. 1051, doi. 10.1038/nsmb.1868

By:

Hirschi, Alexander;
Cecchini, Matthew;
Steinhardt, Rachel C;
Schamber, Michael R;
Dick, Frederick A;
Rubin, Seth M

Publication type:

Article

p53 activates transcription by directing structural shifts in Mediator.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 753, doi. 10.1038/nsmb.1816

By:

Meyer, Krista D.;
Shih-chieh Lin;
Bernecky, Carrie;
Yuefeng Gao;
Taatjes, Dylan J.

Publication type:

Article

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 4, p. 519, doi. 10.1038/nsmb.1793

By:

Wojcik, John;
Hantschel, Oliver;
Grebien, Florian;
Kaupe, Ines;
Bennett, Keiryn L.;
Barkinge, John;
Jones, Richard B.;
Koide, Akiko;
Superti-Furga, Giulio;
Koide, Shohei

Publication type:

Article

Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 3, p. 299, doi. 10.1038/nsmb.1754

By:

Szilard, Rachel K.;
Jacques, Pierre-Étienne;
Laramée, Louise;
Cheng, Benjamin;
Galicia, Sarah;
Bataille, Alain R.;
Yeung, ManTek;
Mendez, Megan;
Bergeron, Maxime;
Robert, François;
Durocher, Daniel

Publication type:

Article

A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 3, p. 365, doi. 10.1038/nsmb.1769

By:

Dong-Hyun Lee;
Yunfeng Pan;
Kanner, Shlomo;
Patrick Sung;
Borowiec, James A.;
Chowdhury, Dipanjan

Publication type:

Article

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 2, p. 216, doi. 10.1038/nsmb.1718

By:

Schneider, Marc;
He-Hsuan Hsiao;
Will, Cindy L.;
Giet, Régis;
Urlaub, Henning;
Lührmann, Reinhard

Publication type:

Article

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 10, p. 1026, doi. 10.1038/nsmb.1656

By:

Kosako, Hidetaka;
Yamaguchi, Nozomi;
Aranami, Chizuru;
Ushiyama, Masato;
Kose, Shingo;
Imamoto, Naoko;
Taniguchi, Hisaaki;
Nishida, Eisuke;
Hattori, Seisuke

Publication type:

Article

PORE-ing over ERK substrates.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 10, p. 1004, doi. 10.1038/nsmb1009-1004

By:

Ahn, Natalie G.

Publication type:

Article

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 9, p. 945, doi. 10.1038/nsmb.1648

By:

Mohideen, Firaz;
Capili, Allan D.;
Bilimoria, Parizad M.;
Yamada, Tomoko;
Bonni, Azad;
Lima, Christopher D.

Publication type:

Article

PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 6, p. 624, doi. 10.1038/nsmb.1606

By:

Cameron, Angus J. M.;
Escribano, Cristina;
Saurin, Adrian T.;
Kostelecky, Brenda;
Parker, Peter J.

Publication type:

Article

Acetylation by GCN5 regulates CDC6 phosphorylation in the S phase of the cell cycle.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 4, p. 412, doi. 10.1038/nsmb.1583

By:

Paolinelli, Roberta;
Mendoza-Maldonado, Ramiro;
Cereseto, Anna;
Giacca, Mauro

Publication type:

Article

CK2α phosphorylates BMAL1 to regulate the mammalian clock.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 4, p. 446, doi. 10.1038/nsmb.1578

By:

Tamaru, Teruya;
Hirayama, Jun;
Isojima, Yasushi;
Nagai, Katsuya;
Norioka, Shigemi;
Takamatsu, Ken;
Sassone-Corsi, Paolo

Publication type:

Article