Works about PHOSPHOINOSITIDES

Results: 3269

Akt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8 T-cell proliferation and survival.

Published in:

OncoImmunology, 2015, v. 4, n. 5, p. 0, doi. 10.1080/2162402X.2015.1005448

By:

Eid, Rasha Abu;
Friedman, Kevin M;
Mkrtichyan, Mikayel;
Walens, Andrea;
King, William;
Janik, John;
Khleif, Samir N

Publication type:

Article

Targeting PI3Kδ One man's meat is another man's poison.

Published in:

OncoImmunology, 2013, v. 2, n. 1, p. e22272-1, doi. 10.4161/onci.22272

By:

Prchal-Murphy, Michaela;
Putz, Eva Maria;
Freissmuth, Michael;
Sexl, Veronika;
Zebedin-Brandl, Eva

Publication type:

Article

Novel mutations of PIK3CA gene in head and neck squamous cell carcinoma.

Published in:

Cancer Biomarkers, 2016, v. 16, n. 3, p. 377, doi. 10.3233/CBM-160576

By:

Al-Amri, Ali M.;
Vatte, Chittibabu;
Cyrus, Cyril;
Chathoth, Shahanas;
Hashim, Tariq Mohammad;
Mohamed, Yehia S.;
Ali, Rudaynah Al;
Alsaid, Abir;
Ali, Amein Al

Publication type:

Article

An Emerging Role for Phosphoinositides in the Pathophysiology of Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2021, v. 11, n. 4, p. 1725, doi. 10.3233/JPD-212684

By:

Schechter, Meir;
Sharon, Ronit

Publication type:

Article

Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium- calcium exchanger NCX1.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105396

By:

Jing Xue;
Weizhong Zeng;
John, Scott;
Attiq, Nicole;
Ottolia, Michela;
Youxing Jiang

Publication type:

Article

Sorting nexin 10 regulates lysosomal ionic homeostasis via ClC-7 by controlling PI(3,5)P<sub>2</sub>.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 6, p. 1, doi. 10.1083/jcb.202408174

By:

Jing Ze Wu;
Pemberton, Joshua G.;
Shin Morioka;
Junko Sasaki;
Bablani, Priya;
Takehiko Sasaki;
Balla, Tamas;
Grinstein, Sergio;
Freeman, Spencer A.

Publication type:

Article

Formation of Membrane Domains via Actin Waves: A Fundamental Principle in the Generation of Dynamic Structures in Phagocytes.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4759, doi. 10.3390/ijms26104759

By:

Takito, Jiro;
Nonaka, Naoko

Publication type:

Article

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 6, p. 721, doi. 10.1038/nsmb.2076

By:

Toledo, Luis I.;
Murga, Matilde;
Zur, Rafal;
Soria, Rebeca;
Rodriguez, Antonio;
Martinez, Sonia;
Oyarzabal, Julen;
Pastor, Joaquin;
Bischoff, James R.;
Fernandez-Capetillo, Oscar

Publication type:

Article

Structural basis for the Rho- and phosphoinositide-dependent localization of the exocyst subunit Sec3.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 2, p. 180, doi. 10.1038/nsmb.1722

By:

Yamashita, Masami;
Kurokawa, Kazuo;
Sato, Yusuke;
Yamagata, Atsushi;
Mimura, Hisatoshi;
Yoshikawa, Azusa;
Sato, Ken;
Nakano, Akihiko;
Fukai, Shuya

Publication type:

Article

Research Highlights.

Published in:: Nature Structural & Molecular Biology, 2007, v. 14, n. 8, p. 688, doi. 10.1038/nsmb0807-688
Publication type:: Article

Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 11, p. 1029, doi. 10.1038/nsmb1160

By:

Alam, Steven L.;
Langelier, Charles;
Whitby, Frank G.;
Koirala, Sajjan;
Robinson, Howard;
Hill, Christopher P.;
Sundquist, Wesley I.

Publication type:

Article

Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 11, p. 1031, doi. 10.1038/nsmb1163

By:

Hirano, Satoshi;
Suzuki, Nobuhiro;
Slagsvold, Thomas;
Kawasaki, Masato;
Trambaiolo, Daniel;
Kato, Ryuichi;
Stenmark, Harald;
Wakatsuki, Soichi

Publication type:

Article

Bacterial pathogenesis: Messing up the membrane.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 10, p. 680, doi. 10.1038/nrmicro2442

By:

David, Rachel

Publication type:

Article

Pseudomonas makes its own bed.

Published in:

Nature Reviews Microbiology, 2007, v. 5, n. 6, p. 399, doi. 10.1038/nrmicro1683

By:

Jones, Susan

Publication type:

Article

Exploiting the host.

Published in:

Nature Reviews Microbiology, 2006, v. 4, n. 7, p. 492, doi. 10.1038/nrmicro1451

By:

Amoils, Shannon

Publication type:

Article

3-Phosphoinositide-dependent protein kinase-1/Akt signalling and inhibition in a canine prostate carcinoma cell line.

Published in:

Veterinary & Comparative Oncology, 2007, v. 5, n. 1, p. 47, doi. 10.1111/j.1476-5829.2006.00117.x

By:

Alvarez, F. J.;
Murahari, S.;
Couto, C. G.;
Rosol, T. J.;
Kulp, S. K.;
Chen, C.-S.;
Kisseberth, W. C.

Publication type:

Article

Rational Design and Synthesis of D‐galactosyl Lysophospholipids as Selective Substrates and non‐ATP‐competitive Inhibitors of Phosphatidylinositol Phosphate Kinases.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 2, p. 1, doi. 10.1002/chem.202202083

By:

Sun, Mengxia;
Zhang, Chi;
Sui, Dexin;
Yang, Canchai;
Pyeon, Dohun;
Huang, Xuefei;
Hu, Jian

Publication type:

Article

Synthesis and Cellular Labeling of Caged Phosphatidylinositol Derivatives.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 2, p. 384, doi. 10.1002/chem.201903704

By:

Müller, Rainer;
Citir, Mevlut;
Hauke, Sebastian;
Schultz, Carsten

Publication type:

Article

Asymmetric Dearomatization of β-Naphthols through an Amination Reaction Catalyzed by a Chiral Phosphoric Acid.

Published in:

Angewandte Chemie, 2015, v. 127, n. 2, p. 657, doi. 10.1002/ange.201409756

By:

Wang, Shou ‐ Guo;
Yin, Qin;
Zhuo, Chun ‐ Xiang;
You, Shu ‐ Li

Publication type:

Article

A Rapidly Reversible Chemical Dimerizer System to Study Lipid Signaling in Living Cells.

Published in:

Angewandte Chemie, 2014, v. 126, n. 26, p. 6838, doi. 10.1002/ange.201402294

By:

Feng, Suihan;
Laketa, Vibor;
Stein, Frank;
Rutkowska, Anna;
MacNamara, Aidan;
Depner, Sofia;
Klingmüller, Ursula;
Saez-Rodriguez, Julio;
Schultz, Carsten

Publication type:

Article

Kinetic Resolution of Secondary Alcohols Catalyzed by Chiral Phosphoric Acids.

Published in:

Angewandte Chemie, 2013, v. 125, n. 39, p. 10417, doi. 10.1002/ange.201304281

By:

Harada, Shingo;
Kuwano, Satoru;
Yamaoka, Yousuke;
Yamada, Ken-ichi;
Takasu, Kiyosei

Publication type:

Article

Syringin from Tinospora crispa downregulates pro-inflammatory mediator production through MyD88-dependent pathways in lipopolysaccharide (LPS)-induced U937 macrophages.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09722-z

By:

Arshad, Laiba;
Haque, Md. Areeful;
Harikrishnan, Hemavathy;
Ibrahim, Sarah;
Jantan, Ibrahim

Publication type:

Article

Mode switching of Inositol 1,4,5-trisphosphate receptor channel shapes the Spatiotemporal scales of Ca signals.

Published in:

Journal of Biological Physics, 2016, v. 42, n. 4, p. 507, doi. 10.1007/s10867-016-9419-2

By:

Ullah, Ghanim;
Ullah, Aman

Publication type:

Article

Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling.

Published in:

BioMetals, 2014, v. 27, n. 2, p. 317, doi. 10.1007/s10534-014-9714-y

By:

Hamann, Ingrit;
Petroll, Kerstin;
Hou, Xiaoqing;
Anwar-Mohamed, Anwar;
El-Kadi, Ayman;
Klotz, Lars-Oliver

Publication type:

Article

Regulation of renal artery smooth muscle tone by α<sub>1</sub>-adrenoceptors: role of voltage-gated calcium channels and intracellular calcium stores.

Published in:

Urological Research, 2000, v. 28, n. 2, p. 122, doi. 10.1007/s002400050149

By:

Eckert, R. E.;
Karsten, A. J.;
Utz, J.;
Ziegler, M.

Publication type:

Article

MFGE8 mitigates brain injury in a rat model of SAH by maintaining vascular endothelial integrity via TIGβ5/PI3K/CXCL12 signaling.

Published in:

Experimental Brain Research, 2021, v. 239, n. 7, p. 2193, doi. 10.1007/s00221-021-06111-x

By:

Wang, Jikai;
Wang, Yiping;
Zuo, Yuchun;
Duan, Jiajia;
Pan, Aihua;
Li, Jian-Ming;
Yan, Xiao-Xin;
Liu, Fei

Publication type:

Article

Cryptotanshinone protects primary rat cortical neurons from glutamate-induced neurotoxicity via the activation of the phosphatidylinositol 3-kinase/Akt signaling pathway.

Published in:

Experimental Brain Research, 2009, v. 193, n. 1, p. 109, doi. 10.1007/s00221-008-1600-9

By:

Fangyan Zhang;
Wenhua Zheng;
Rongbiao Pi;
Zhengrong Mei;
Yingxia Bao;
Jie Gao;
Wenjie Tang;
Shaorui Chen;
Peiqing Liu

Publication type:

Article

The role of PI3Kα isoform in cardioprotection.

Published in:

Basic Research in Cardiology, 2017, v. 112, n. 6, p. 1, doi. 10.1007/s00395-017-0657-7

By:

Rossello, Xavier;
Riquelme, Jaime;
He, Zhenhe;
Taferner, Stasa;
Vanhaesebroeck, Bart;
Davidson, Sean;
Yellon, Derek

Publication type:

Article

Acute erythropoietin cardioprotection is mediated by endothelial response.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 3, p. 343, doi. 10.1007/s00395-011-0158-z

By:

Teng, Ruifeng;
Calvert, John;
Sibmooh, Nathawut;
Piknova, Barbora;
Suzuki, Norio;
Sun, Junhui;
Martinez, Kevin;
Yamamoto, Masayuki;
Schechter, Alan;
Lefer, David;
Noguchi, Constance

Publication type:

Article

Attenuation of infarction in cynomolgus monkeys: preconditioning and postconditioning.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 1, p. 119, doi. 10.1007/s00395-009-0050-2

By:

Xi-Ming Yang;
Yanping Liu;
Yongge Liu;
Tandon, Narendra;
Kambayashi, Junichi;
Downey, James;
Cohen, Michael

Publication type:

Article

Redox signaling at reperfusion is required for protection from ischemic preconditioning but not from a direct PKC activator.

Published in:

Basic Research in Cardiology, 2008, v. 103, n. 1, p. 54, doi. 10.1007/s00395-007-0683-y

By:

Yanping Liu;
Xi-Ming Yang;
Iliodromitis, Efstathios;
Kremastinos, Dimitrios;
Dost, Turhan;
Cohen, Michael;
Downey, James

Publication type:

Article

Sustained release of PI3K inhibitor from PHA nanoparticles and in vitro growth inhibition of cancer cell lines.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 89, n. 5, p. 1423, doi. 10.1007/s00253-011-3101-1

By:

Xiao-Yun Lu;
Ciraolo, Elisa;
Stefenia, Rachele;
Guo-Qiang Chen;
Yali Zhang;
Hirsch, Emilio

Publication type:

Article

High yield of long-chain polyunsaturated fatty acids by labyrinthulids on soybean lecithin-dispersed agar medium.

Published in:

Applied Microbiology & Biotechnology, 2005, v. 69, n. 3, p. 253, doi. 10.1007/s00253-005-1978-2

By:

Kumon, Yasuyuki;
Yokochi, Toshihiro;
Nakahara, Toro

Publication type:

Article

Membrane phosphoinositides and protein-membrane interactions.

Published in:

Amino Acids, 2013, v. 45, n. 4, p. 751, doi. 10.1007/s00726-013-1512-2

By:

Gokhale, Nikhil

Publication type:

Article

S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.

Published in:

Amino Acids, 2011, v. 41, n. 1, p. 205, doi. 10.1007/s00726-011-0834-1

By:

Pan, Li-Long;
Liu, Xin-Hua;
Gong, Qi-Hai;
Zhu, Yi-Zhun

Publication type:

Article

New Therapies for Chronic Obstructive Pulmonary Disease.

Published in:

Medical Principles & Practice, 2010, v. 19, n. 5, p. 330, doi. 10.1159/000316368

By:

Barnes, Peter J.

Publication type:

Article

Organismal roles for the PI3Kα and β isoforms: their specificity, redundancy or cooperation is context-dependent.

Published in:

Biochemical Journal, 2021, v. 478, n. 6, p. 1199, doi. 10.1042/BCJ20210004

By:

Arcucci, Silvia;
Ramos-Delgado, Fernanda;
Cayron, Coralie;
Therville, Nicole;
Gratacap, Marie-Pierre;
Basset, Céline;
Thibault, Benoit;
Guillermet-Guibert, Julie

Publication type:

Article

Phosphoinositide lipids in primary cilia biology.

Published in:

Biochemical Journal, 2020, v. 477, n. 18, p. 3541, doi. 10.1042/BCJ20200277

By:

Conduit, Sarah E.;
Vanhaesebroeck, Bart

Publication type:

Article

Synthesis of porous aluminum phosphate bulks by hydrothermal hot pressing process and their analytical characterizations.

Published in:

Inorganic Materials, 2009, v. 45, n. 9, p. 1048, doi. 10.1134/S0020168509090180

By:

Onoda, H.;
Sakai, R.;
Nakahira, A.;
Tanaka, I.

Publication type:

Article

Signalling: PI3Kδ keeps TLR4 signalling on track.

Published in:

2012

By:

Papatriantafyllou, Maria

Publication type:

journal article

Signalling: PI3Kβ - linking signals for neutrophil activation.

Published in:

2011

By:

Woodman, Isabel

Publication type:

journal article

In brief.

Published in:: 2010
Publication type:: Abstract

PI3Kδ and PI3Kγ: partners in crime in inflammation in rheumatoid arthritis and beyond?

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 3, p. 191, doi. 10.1038/nri2036

By:

Rommel, Christian;
Camps, Montserrat;
Hong Ji

Publication type:

Article

From the editors.

Published in:: Nature Reviews Immunology, 2007, v. 7, n. 3, p. 169, doi. 10.1038/nri2050
Publication type:: Article

Integrated signalling pathways for mast-cell activation.

Published in:

Nature Reviews Immunology, 2006, v. 6, n. 3, p. 218, doi. 10.1038/nri1782

By:

Gilfillan, Alasdair M.;
Tkaczyk, Christine

Publication type:

Article

Mechanisms of type-I- and type-II-interferon-mediated signalling.

Published in:

Nature Reviews Immunology, 2005, v. 5, n. 5, p. 375, doi. 10.1038/nri1604

By:

Platanias, Leonidas C.

Publication type:

Article

Allergy: Mast cells make the most of p110d.

Published in:

Nature Reviews Immunology, 2004, v. 4, n. 12, p. 928, doi. 10.1038/nri1517

By:

Bird, Lucy

Publication type:

Article

It's a knockout!

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 11, p. 844, doi. 10.1038/nri1239

By:

Kirsty

Publication type:

Article

PI3K in lymphocyte development, differentiation and activation.

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 4, p. 317, doi. 10.1038/nri1056

By:

Okkenhaug, Klaus;
Vanhaesebroeck, Bart

Publication type:

Article

Lymphocyte signalling: Isoform isolated.

Published in:

Nature Reviews Immunology, 2002, v. 2, n. 9, p. 626, doi. 10.1038/nri894

By:

Buckland, Jenny

Publication type:

Article