Works matching DE "PHOSPHODIESTERASES"

Results: 1788

A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes.

Published in:

OncoImmunology, 2013, v. 2, n. 9, p. e26246-1, doi. 10.4161/onci.26246

By:

Horenstein, Alberto L.;
Chillemi, Antonella;
Zaccarello, Gianluca;
Bruzzone, Santina;
Quarona, Valeria;
Zito, Andrea;
Serra, Sara;
Malavasi, Fabio

Publication type:

Article

Inhibition of phosphodiesterases 1 and 4 prevents myofibroblast transformation in Peyronie's disease.

Published in:

BJU International, 2025, v. 135, n. 5, p. 810, doi. 10.1111/bju.16631

By:

Harding, Sophie L.;
Ilg, Marcus M.;
Bustin, Stephen A.;
Ralph, David J.;
Cellek, Selim

Publication type:

Article

Mechanism of repair of 5?-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 12, p. 1363, doi. 10.1038/nsmb.2418

By:

Schellenberg, Matthew J;
Appel, C Denise;
Adhikari, Sanjay;
Robertson, Patrick D;
Ramsden, Dale A;
Williams, R Scott

Publication type:

Article

RAF-isotype switching: from B to C through PDE.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 517, doi. 10.1038/nsmb.2063

By:

Lau, Eric;
Ronai, Ze'ev

Publication type:

Article

ERK and PDE4 cooperate to induce RAF isoform switching in melanoma.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 584, doi. 10.1038/nsmb.2022

By:

Marquette, Amélie;
André, Jocelyne;
Bagot, Martine;
Bensussan, Armand;
Dumaz, Nicolas

Publication type:

Article

Structural basis of substrate discrimination and integrin binding by autotaxin.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 2, p. 198, doi. 10.1038/nsmb.1980

By:

Hausmann, Jens;
Kamtekar, Satwik;
Christodoulou, Evangelos;
Day, Jacqueline E.;
Tao Wu;
Fulkerson, Zachary;
Albers, Harald M. H. G.;
van Meeteren, Laurens A.;
Houben, Anna J. S.;
van Zeijl, Leonie;
Jansen, Silvia;
Andries, Maria;
Hall, Troii;
Pegg, Lyle E.;
Benson, Timothy E.;
Kasiem, Mobien;
Harlos, Karl;
Kooi, Craig W. Vander;
Smyth, Susan S.;
Ovaa, Huib

Publication type:

Article

Location, location, location: a crystal-clear view of autotaxin saturating LPA receptors.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 2, p. 117, doi. 10.1038/nsmb0211-117

By:

Tabchy, Adel;
Tigyi, Gabor;
Mills, Gordon B.

Publication type:

Article

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 2, p. 205, doi. 10.1038/nsmb.1998

By:

Nishimasu, Hiroshi;
Okudaira, Shinichi;
Hama, Kotaro;
Mihara, Emiko;
Dohmae, Naoshi;
Inoue, Asuka;
Ishitani, Ryuichiro;
Takagi, Junichi;
Aoki, Junken;
Nureki, Osamu

Publication type:

Article

Bacterial physiology: HD-GYP domain structure solved.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 1, p. 4, doi. 10.1038/nrmicro3191

By:

Molloy, Sheilagh

Publication type:

Article

Function, structure and mechanism of bacterial photosensory LOV proteins.

Published in:

Nature Reviews Microbiology, 2011, v. 9, n. 10, p. 713, doi. 10.1038/nrmicro2622

By:

Herrou, Julien;
Crosson, Sean

Publication type:

Article

Tadalafil significantly reduces ischemia reperfusion injury in skin island flaps.

Published in:

Indian Journal of Plastic Surgery, 2013, v. 46, n. 1, p. 75, doi. 10.4103/0970-0358.113714

By:

Kayiran, Oguz;
Cuzdan, Suat S.;
Uysal, Afsin;
Kocer, Ugur

Publication type:

Article

Role of gap junction-mediated communications in regulating large-scale chromatin configuration remodeling and embryonic developmental competence acquisition in fully grown bovine oocyte.

Published in:

Journal of Assisted Reproduction & Genetics, 2013, v. 30, n. 9, p. 1219, doi. 10.1007/s10815-013-0061-7

By:

Lodde, Valentina;
Franciosi, Federica;
Tessaro, Irene;
Modina, Silvia;
Luciano, Alberto

Publication type:

Article

DeCODE Scientists Decode Stroke Gene.

Published in:

Bio-IT World, 2003, v. 2, n. 11, p. 16

By:

Strattner, Tony

Publication type:

Article

Catalytic enhancement of the heme-based oxygen-sensing phosphodiesterase EcDOS by hydrogen sulfide is caused by changes in heme coordination structure.

Published in:

BioMetals, 2015, v. 28, n. 4, p. 637, doi. 10.1007/s10534-015-9847-7

By:

Yan, Fang;
Fojtikova, Veronika;
Man, Petr;
Stranava, Martin;
Martínková, Markéta;
Du, Yongming;
Huang, Dongyang;
Shimizu, Toru

Publication type:

Article

Conversion of a heme-based oxygen sensor to a heme oxygenase by hydrogen sulfide: effects of mutations in the heme distal side of a heme-based oxygen sensor phosphodiesterase ( Ec DOS).

Published in:

BioMetals, 2013, v. 26, n. 5, p. 839, doi. 10.1007/s10534-013-9640-4

By:

Du, Yongming;
Liu, Gefei;
Yan, Yinxia;
Huang, Dongyang;
Luo, Wenhong;
Martinkova, Marketa;
Man, Petr;
Shimizu, Toru

Publication type:

Article

The effect of divalent cations on the catalytic activity of the human plasma 3′-exonuclease.

Published in:

BioMetals, 2010, v. 23, n. 6, p. 1113, doi. 10.1007/s10534-010-9358-5

By:

Wojcik, Marzena;
Stec, Wojciech

Publication type:

Article

The effect of DA-8159 on corpus cavernosal smooth muscle relaxation and penile erection in diabetic rabbits.

Published in:

Urological Research, 2004, v. 32, n. 2, p. 107, doi. 10.1007/s00240-003-0387-1

By:

Kang, Kyung Koo;
Choi, Seul Min;
Ahn, Gook Jun;
Kwon, Jong Won;
Kim, Won Bae

Publication type:

Article

Identification and functional study of phosphodiesterases in rat urinary bladder.

Published in:

Urological Research, 2001, v. 29, n. 6, p. 388, doi. 10.1007/s00240-001-0221-6

By:

Yuhong Qiu;
Kraft, Patricia;
Craig, Elizabeth C.;
Xiulin Liu;
Haynes-Johnson, Donna

Publication type:

Article

Relaxation of human ureteral smooth muscle in vitro by modulation of cyclic nucleotide-dependent pathways.

Published in:

Urological Research, 2000, v. 28, n. 2, p. 110

By:

Kühn, Rainer;
&Ückert, Stefan;
Stief, Christian G.;
Truss, Michael C.;
Lietz, Burckhard;
Bischoff, Erwin;
Schramm, Matthias;
Jonas, Udo

Publication type:

Article

Bifurcation and dynamics in a mathematical model of early atherosclerosis.

Published in:

Journal of Mathematical Biology, 2015, v. 71, n. 6/7, p. 1451, doi. 10.1007/s00285-015-0864-5

By:

Chalmers, Alexander;
Cohen, Anna;
Bursill, Christina;
Myerscough, Mary

Publication type:

Article

Selective PDE5A inhibition with sildenafil rescues left ventricular dysfunction, inflammatory immune response and cardiac remodeling in angiotensin II-induced heart failure in vivo.

Published in:

Basic Research in Cardiology, 2012, v. 107, n. 6, p. 1, doi. 10.1007/s00395-012-0308-y

By:

Westermann, Dirk;
Becher, Peter;
Lindner, Diana;
Savvatis, Kostantinos;
Xia, Yu;
Fröhlich, Matthias;
Hoffmann, Sebastian;
Schultheiss, Heinz-Peter;
Tschöpe, Carsten

Publication type:

Article

Prostaglandin E facilitates inotropic effects of 5-HT serotonin receptors and β-adrenoceptors in failing human heart.

Published in:

Basic Research in Cardiology, 2012, v. 107, n. 5, p. 1, doi. 10.1007/s00395-012-0295-z

By:

Riise, Jon;
Ørstavik, Øivind;
Qvigstad, Eirik;
Dahl, Christen;
Osnes, Jan-Bjørn;
Skomedal, Tor;
Levy, Finn;
Krobert, Kurt

Publication type:

Article

Regulation by phosphodiesterase isoforms of protein kinase A-mediated attenuation of myocardial protein kinase D activation.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 1, p. 51, doi. 10.1007/s00395-010-0116-1

By:

Haworth, Robert;
Cuello, Friederike;
Avkiran, Metin

Publication type:

Article

PDE5A suppression of acute β-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 3, p. 337, doi. 10.1007/s00395-010-0084-5

By:

Lee, Dong I.;
Vahebi, Susan;
Tocchetti, Carlo Gabriele;
Barouch, Lili A.;
Solaro, R. John;
Takimoto, Eiki;
Kass, David A.

Publication type:

Article

Antiproliferative effect of sildenafil on human pulmonary artery smooth muscle cells.

Published in:

Basic Research in Cardiology, 2005, v. 100, n. 2, p. 131, doi. 10.1007/s00395-004-0504-5

By:

Tantini, Benedetta;
Manes, Alessandra;
Fiumana, Emanuela;
Pignatti, Carla;
Guarnieri, Carlo;
Zannoli, Romano;
Branzi, Angelo;
Galié, Nazzareno

Publication type:

Article

PDE3 cyclic nucleotide phosphodiesterases and the compartmentation of cyclic nucleotide-mediated signalling in cardiac myocytes.

Published in:

Basic Research in Cardiology, 2002, v. 97, p. I83

By:

Movsesian, Matthew A.

Publication type:

Article

Mutational analysis of wheat ( Triticum aestivum L.) nucleotide pyrophosphatase/phosphodiesterase shows the role of six amino acids in the catalytic mechanism.

Published in:

Applied Microbiology & Biotechnology, 2011, v. 90, n. 1, p. 173, doi. 10.1007/s00253-010-2962-z

By:

Joye, Iris J.;
Beliën, Tim;
Brijs, Kristof;
Soetaert, Wim;
Delcour, Jan A.

Publication type:

Article

Cloning, stable expression of human phosphodiesterase 7A and development of an assay for screening of PDE7 selective inhibitors.

Published in:

Applied Microbiology & Biotechnology, 2008, v. 77, n. 5, p. 1167, doi. 10.1007/s00253-007-1230-3

By:

Malik, Renu;
Bora, Roop Singh;
Gupta, Dikshi;
Sharma, Pratibha;
Arya, Ranjana;
Chaudhary, Shiwani;
Saini, Kulvinder Singh

Publication type:

Article

Utilization of phosphate diesters by phosphodiesterase-producing marine diatoms.

Published in:

Journal of Plankton Research, 2014, v. 36, n. 1, p. 281, doi. 10.1093/plankt/fbt091

By:

Yamaguchi, Haruo;
Arisaka, Hiroshi;
Otsuka, Naoki;
Tomaru, Yuji

Publication type:

Article

Utilization of phosphate diester by the marine diatom <it>Chaetoceros ceratosporus</it>.

Published in:

Journal of Plankton Research, 2005, v. 27, n. 6, p. 603, doi. 10.1093/plankt/fbi027

By:

YAMAGUCHI, HARUO;
YAMAGUCHI, MINEO;
FUKAMI, KIMIO;
ADACHI, MASAO;
NISHIJIMA, TOSHITAKA

Publication type:

Article

Cadmium inhibits brain calmodulin: In vitro and in vivo studies.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1989, v. 43, n. 4, p. 541, doi. 10.1007/BF01701932

By:

Vig, P.;
Bhatia, M.;
Gill, K.;
Nath, R.

Publication type:

Article

Effect of Pretreatment with Cilostazol on Spinal Cord Ischemia-reperfusion Injury in Rats.

Published in:

European Archives of Medical Research, 2021, v. 37, n. 4, p. 229, doi. 10.4274/eamr.galenos.2021.02411

By:

Kulaçoğlu, Ülkü Kafa;
Kalko, Yusuf;
Şentürk, Gözde Erkanlı

Publication type:

Article

Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.

Published in:

Drug Metabolism Reviews, 2014, v. 46, n. 4, p. 494, doi. 10.3109/03602532.2014.971957

By:

Comeaux, Evan Q.;
van Waardenburg, Robert C. A. M.

Publication type:

Article

113. O-GLUCURONIDATION OF THE PHOSPHODIESTERASE 4 INHIBITOR AWD 12-281 IN HUMAN LIVER MICROSOMES AND RECOMBINANT UDP-GLUCURONOSYLTRANSFERASES.

Published in:: 2003
Publication type:: Abstract

The Selective Phosphodiesterase 9 (PDE9) Inhibitor PF-04447943 Attenuates a Scopolamine-Induced Deficit in a Novel Rodent Attention Task.

Published in:

Journal of Neurogenetics, 2011, v. 25, n. 4, p. 120, doi. 10.3109/01677063.2011.630494

By:

Vardigan, Joshua D.;
Converso, Antonella;
Hutson, Pete H.;
Uslaner, Jason M.

Publication type:

Article

Dual PDE3/4 and PDE4 Inhibitors: Novel Treatments For COPD and Other Inflammatory Airway Diseases.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 114, n. 5, p. 365, doi. 10.1111/bcpt.12209

By:

Abbott‐Banner, Katharine H.;
Page, Clive P.

Publication type:

Article

Design of experiment avenue for development and validation of RP-HPLC-PDA method for determination of apremilast in bulk and in in-house tablet formulation.

Published in:

Journal of Analytical Science & Technology, 2019, v. 10, n. 1, p. 1, doi. 10.1186/s40543-019-0170-8

By:

Chaudhari, Suraj R.;
Shirkhedkar, Atul A.

Publication type:

Article

PDE5 inhibitors for LUTS.

Published in:

Prostate Cancer & Prostatic Diseases, 2009, v. 12, n. 4, p. 316, doi. 10.1038/pcan.2009.27

By:

Mouli, S.;
McVary, K. T.

Publication type:

Article

Prostate News.

Published in:: Prostate Cancer & Prostatic Diseases, 2007, v. 10, n. 4, p. 312, doi. 10.1038/sj.pcan.4501023
Publication type:: Article

Cilostazol attenuates kainic acid-induced hippocampal cell death.

Published in:

Korean Journal of Physiology & Pharmacology, 2018, v. 22, n. 1, p. 63, doi. 10.4196/kjpp.2018.22.1.63

By:

Park, Young-Seop;
Zhen Jin;
Eun Ae Jeong;
Chin-ok Yi;
Jong Youl Lee;
Park, In Sung;
Gu Seob Roh

Publication type:

Article

Relaxant and anti-inflammatory effect of two thalidomide analogs as PDE-4 inhibitors in pregnant rat uterus.

Published in:

Korean Journal of Physiology & Pharmacology, 2017, v. 21, n. 4, p. 429, doi. 10.4196/kjpp.2017.21.4.429

By:

Muñoz-Pérez, Víctor Manuel;
Fernández-Martínez, Eduardo;
Ponce-Monter, Héctor;
Ortiz, Mario I.

Publication type:

Article

Identification of Lys49-PLA2 from crude venom of Crotalus atrox as a human neutrophil-calcium modulating protein.

Published in:

Korean Journal of Physiology & Pharmacology, 2016, v. 20, n. 2, p. 177, doi. 10.4196/kjpp.2016.20.2.177

By:

Sultan, Md. Tipu;
Hong-Mei Li;
Yong Zu Lee;
Soon Sung Lim;
Dong-Keun Song

Publication type:

Article

Cilostazol Inhibits Vascular Smooth Muscle Cell Proliferation and Reactive Oxygen Species Production through Activation of AMP-activated Protein Kinase Induced by Heme Oxygenase-1.

Published in:

Korean Journal of Physiology & Pharmacology, 2011, v. 15, n. 4, p. 203, doi. 10.4196/kjpp.2011.15.4.203

By:

Jung Eun Kim;
Jin Young Sung;
Chang-Hoon Woo;
Young Jin Kang;
Kwang Youn Lee;
Hee Sun Kim;
Woo Hyung Kwun;
Hyoung Chul Choi

Publication type:

Article

Genetic fingerprinting and identification of differentially expressed genes in isolates of Leishmania donovanifrom Indian patients of post-kala-azar dermal leishmaniasis.

Published in:: Parasitology, 2008, v. 135, n. 1, p. 23, doi. 10.1017/S0031182007003484
Publication type:: Article

Knockdown of phosphodiesterase 4D inhibits nasopharyngeal carcinoma proliferation via the epidermal growth factor receptor signaling pathway.

Published in:

Oncology Letters, 2014, v. 8, n. 5, p. 2110, doi. 10.3892/ol.2014.2422

By:

TING XU;
SIHAI WU;
YUAN YUAN;
GUOXIN YAN;
DAJIANG XIAO

Publication type:

Article

Pentoxifylline attenuates the local and systemic inflammatory response after infrarenal abdominal aortic ischemia-reperfusion.

Published in:

Clinical Hemorheology & Microcirculation, 2017, v. 65, n. 3, p. 229, doi. 10.3233/CH-16169

By:

Nagy, Tibor;
Hardi, Péter;
Takács, Ildikó;
Tóth, Mónika;
Petrovics, Laura;
Jancsó, Gábor;
Sínay, László;
Fazekas, Gábor;
Pintér, Örs;
Arató, Endre

Publication type:

Article

Efficient Cleavage of pUC19 DNA by Tetraaminonaphthols.

Published in:

ChemistryOpen, 2025, v. 14, n. 2, p. 1, doi. 10.1002/open.202400157

By:

Kost, Catharina;
Scheffer, Ute;
Kalden, Elisabeth;
Göbel, Michael Wilhelm

Publication type:

Article

Treatment effects of phosphodiesterase-5 inhibitors may improve with time following nerve-sparing radical prostatectomy.

Published in:

Scandinavian Journal of Urology (Taylor & Francis Ltd), 2018, v. 52, n. 2, p. 108, doi. 10.1080/21681805.2017.1387603

By:

Fode, Mikkel;
Østergren, Peter Busch;
Jensen, Christian Fuglesang S.;
Jakobsen, Henrik;
Sønksen, Jens

Publication type:

Article

Testosterone replacement in transgenic sickle cell mice controls priapic activity and upregulates PDE5 expression and eNOS activity in the penis.

Published in:

Andrology, 2018, v. 6, n. 1, p. 184, doi. 10.1111/andr.12442

By:

Musicki, B.;
Karakus, S.;
Akakpo, W.;
Silva, F. H.;
Liu, J.;
Chen, H.;
Zirkin, B. R.;
Burnett, A. L.

Publication type:

Article

Structural and Functional Integration of Tissue-Nonspecific Alkaline Phosphatase Within the Alkaline Phosphatase Superfamily: Evolutionary Insights and Functional Implications.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 12, p. 659, doi. 10.3390/metabo14120659

By:

Imam, Iliass;
Rautureau, Gilles Jean Philippe;
Violot, Sébastien;
Mulard, Eva Drevet;
Magne, David;
Ballut, Lionel

Publication type:

Article