Works about PHOSPHATIDYLINOSITOLS

Results: 360

Synaptotagmin-1 binds to PIP2-containing membrane but not to SNAREs at physiological ionic strength.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 10, p. 815, doi. 10.1038/nsmb.3097

By:

Park, Yongsoo;
Seo, Jong Bae;
Fraind, Alicia;
Pérez-Lara, Angel;
Yavuz, Halenur;
Han, Kyungreem;
Jung, Seung-Ryoung;
Kattan, Iman;
Walla, Peter Jomo;
Choi, MooYoung;
Cafiso, David S;
Koh, Duk-Su;
Jahn, Reinhard

Publication type:

Article

Controlling synaptotagmin activity by electrostatic screening.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 10, p. 991, doi. 10.1038/nsmb.2375

By:

Park, Yongsoo;
Hernandez, Javier M;
van den Bogaart, Geert;
Ahmed, Saheeb;
Holt, Matthew;
Riedel, Dietmar;
Jahn, Reinhard

Publication type:

Article

Determination of association constants of monovalent ions to sphingomyelin and phosphatidylinositol liposomal membranes by microelectrophoresis.

Published in:

Soft Materials, 2017, v. 15, n. 1, p. 113, doi. 10.1080/1539445X.2016.1268625

By:

Dobrzyńska, Izabela;
Kotyńska, Joanna;
Szachowicz-Petelska, Barbara;
Figaszewski, Zbigniew A.

Publication type:

Article

Attempted application of bioengineered/biosynthetic supporting matrices with phosphatidylinositol-trisphosphate-enhancing substances to organ culture of human primordial follicles.

Published in:

Journal of Assisted Reproduction & Genetics, 2013, v. 30, n. 10, p. 1279, doi. 10.1007/s10815-013-0052-8

By:

Lerer-Serfaty, Galit;
Samara, Nivin;
Fisch, Benjamin;
Shachar, Michal;
Kossover, Olga;
Seliktar, Dror;
Ben-Haroush, Avi;
Abir, Ronit

Publication type:

Article

A butterfly effect in cancer.

Published in:

Molecular & Cellular Oncology, 2016, v. 3, n. 1, p. 1, doi. 10.1080/23723556.2015.1029063

By:

Vogt, Peter K;
Hart, Jonathan R;
Yates, John R

Publication type:

Article

Interference of P‑REX2a may inhibit proliferation and reverse the resistance of SGC7901 cells to doxorubicin.

Published in:

Oncology Letters, 2018, v. 15, n. 3, p. 3185, doi. 10.3892/ol.2017.7693

By:

Ai, Yaowei;
Zhou, Qiaohui;
Li, Ling;
Pan, Zhihong;
Guo, MingwEN;
Han, Jingbo

Publication type:

Article

ABT-737 and pictilisib synergistically enhance pitavastatin-induced apoptosis in ovarian cancer cells.

Published in:

Oncology Letters, 2018, v. 15, n. 2, p. 1979, doi. 10.3892/ol.2017.7516

By:

De Wolf, Elizabeth;
De Wolf, Christopher;
Richardson, Alan

Publication type:

Article

PREX2 promotes the proliferation, invasion and migration of pancreatic cancer cells by modulating the PI3K signaling pathway.

Published in:

Oncology Letters, 2016, v. 12, n. 2, p. 1139, doi. 10.3892/ol.2016.4688

By:

JIANYI YANG;
XUEJUN GONG;
LU OUYANG;
WEN HE;
ROU XIAO

Publication type:

Article

Psoralidin inhibits proliferation and enhances apoptosis of human esophageal carcinoma cells via NF-κB and PI3K/Akt signaling pathways.

Published in:

Oncology Letters, 2016, v. 12, n. 2, p. 971, doi. 10.3892/ol.2016.4716

By:

ZHILIANG JIN;
WEI YAN;
HUI JIN;
CHANGZHENG GE;
YANHUA XU

Publication type:

Article

Pazopanib monotherapy in a patient with a malignant granular cell tumor originating from the right orbit: A case report.

Published in:

2015

By:

SACHI MORITA;
MARIKO HIRAMATSU;
MIHOKO SUGISHITA;
BISHAL GYAWALI;
TAKASHI SHIBATA;
TOMOYA SHIMOKATA;
HIROSHI URAKAWA;
AYAKO MITSUMA;
SUZUKO MORITANI;
TOSHINOBU KUBOTA;
SHU ICHIHARA;
YUICHI ANDO

Publication type:

Case Study

Dysregulation of the PI3K/Akt signaling pathway affects cell cycle and apoptosis of side population cells in nasopharyngeal carcinoma.

Published in:

Oncology Letters, 2015, v. 10, n. 1, p. 182, doi. 10.3892/ol.2015.3218

By:

DANWEI ZHENG;
GUANGCHAO ZHU;
SHAN LIAO;
WEI YI;
GENGQIU LUO;
JUNYU HE;
ZHEN PEI;
GUIYUAN LI;
YANHONG ZHOU

Publication type:

Article

Plasma Lipid Profiling of Three Types of Drug-Induced Liver Injury in Japanese Patients: A Preliminary Study.

Published in:

Metabolites (2218-1989), 2020, v. 10, n. 9, p. 355, doi. 10.3390/metabo10090355

By:

Saito, Kosuke;
Kagawa, Tatehiro;
Tsuji, Keiji;
Kumagai, Yuji;
Sato, Ken;
Sakisaka, Shotaro;
Sakamoto, Naoya;
Aiso, Mitsuhiko;
Hirose, Shunji;
Mori, Nami;
Tanaka, Rieko;
Uraoka, Toshio;
Takata, Kazuhide;
Ogawa, Koji;
Mori, Kazuhiko;
Sato, Motonobu;
Nishiya, Takayoshi;
Takamatsu, Kazuhiko;
Arakawa, Noriaki;
Izumi, Takashi

Publication type:

Article

Platelet-activating factor receptor-mediated PI3K/AKT activation contributes to the malignant development of esophageal squamous cell carcinoma.

Published in:

Oncogene, 2015, v. 34, n. 40, p. 5114, doi. 10.1038/onc.2014.434

By:

Chen, J;
Lan, T;
Zhang, W;
Dong, L;
Kang, N;
Zhang, S;
Fu, M;
Liu, B;
Liu, K;
Zhang, C;
Hou, J;
Zhan, Q

Publication type:

Article

Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium.

Published in:

Oncogene, 2014, v. 33, n. 50, p. 5688, doi. 10.1038/onc.2013.507

By:

Nguyen, H N;
Afkari, Y;
Senoo, H;
Sesaki, H;
Devreotes, P N;
Iijima, M

Publication type:

Article

Pathogen and Circadian Controlled 1 (PCC1) regulates polar lipid content, ABA-related responses, and pathogen defence in Arabidopsis thaliana.

Published in:

Journal of Experimental Botany, 2013, v. 64, n. 11, p. 3385, doi. 10.1093/jxb/ert177

By:

Mir, Ricardo;
Hernández, M. Luisa;
Abou-Mansour, Eliane;
Martínez-Rivas, José Manuel;
Mauch, Félix;
Métraux, Jean-Pierre;
León, José

Publication type:

Article

Differential Expression of Serum MicroRNAs Supports CD4+ T Cell Differentiation into Th2/Th17 Cells in Severe Equine Asthma.

Published in:

Genes, 2017, v. 8, n. 12, p. 383, doi. 10.3390/genes8120383

By:

Pacholewska, Alicja;
Kraft, Matthias F.;
Gerber, Vincent;
Jagannathan, Vidhya

Publication type:

Article

UBF complexes with phosphatidylinositol 4,5-bisphosphate in nucleolar organizer regions regardless of ongoing RNA polymerase I activity.

Published in:

Nucleus (1949-1034), 2013, v. 4, n. 6, p. 478, doi. 10.4161/nucl.27154

By:

Sobol, Margarita;
Yildirim, Sukriye;
Philimonenko, Vlada V;
Marášek, Pavel;
Castaño, Enrique;
Hozák, Pavel

Publication type:

Article

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells.

Published in:

Virulence, 2021, v. 12, n. 1, p. 868, doi. 10.1080/21505594.2021.1897247

By:

De Maio, Flavio;
Salustri, Alessandro;
Battah, Basem;
Palucci, Ivana;
Marchionni, Federica;
Bellesi, Silvia;
Palmieri, Valentina;
Papi, Massimiliano;
Kramarska, Eliza;
Sanguinetti, Maurizio;
Sali, Michela;
Berisio, Rita;
Delogu, Giovanni

Publication type:

Article

PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells.

Published in:

Virulence, 2021, v. 12, n. 1, p. 868, doi. 10.1080/21505594.2021.1897247

By:

De Maio, Flavio;
Salustri, Alessandro;
Battah, Basem;
Palucci, Ivana;
Marchionni, Federica;
Bellesi, Silvia;
Palmieri, Valentina;
Papi, Massimiliano;
Kramarska, Eliza;
Sanguinetti, Maurizio;
Sali, Michela;
Berisio, Rita;
Delogu, Giovanni

Publication type:

Article

Adenocarcinoma of the lung with EGFR gene mutation and subsequent resistance mechanisms exploration: case report.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 4517, doi. 10.2147/OTT.S143501

By:

Li Xu;
Qian Z. Wang;
Lin Wu

Publication type:

Article

Primary concomitant EGFR T790M mutation predicted worse prognosis in non-small cell lung cancer patients.

Published in:

OncoTargets & Therapy, 2014, v. 7, p. 513, doi. 10.2147/OTT.S60122

By:

Hang Li;
Haichuan Hu;
Rui Wang;
Yunjian Pan;
Lei Wang;
Yuan Li;
Yang Zhang;
Ting Ye;
Yiliang Zhang;
Bin Li;
Lei Shen;
Yihua Sun;
Haiquan Chen

Publication type:

Article

PIK3CA mutations define favorable prognostic biomarkers in operable breast cancer: a systematic review and meta-analysis.

Published in:

OncoTargets & Therapy, 2014, v. 7, p. 543, doi. 10.2147/OTT.S60115

By:

Yi-Rong Liu;
Yi-Zhou Jiang;
Wen-Jia Zuo;
Ke-Da Yu;
Zhi-Ming Shao

Publication type:

Article

Serum phosphatidylinositol as a biomarker for bipolar disorder liability.

Published in:

Bipolar Disorders, 2017, v. 19, n. 2, p. 107, doi. 10.1111/bdi.12468

By:

Knowles, Emma EM;
Meikle, Peter J;
Huynh, Kevin;
Göring, Harald HH;
Olvera, Rene L;
Mathias, Samuel R;
Duggirala, Ravi;
Almasy, Laura;
Blangero, John;
Curran, Joanne E;
Glahn, David C

Publication type:

Article

Ligand-activated PPARδ inhibits angiotensin II-stimulated hypertrophy of vascular smooth muscle cells by targeting ROS.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0210482

By:

Kang, Eun Sil;
Hwang, Jung Seok;
Lee, Won Jin;
Lee, Gyeong Hee;
Choi, Mi-Jung;
Paek, Kyung Shin;
Lim, Dae-Seog;
Seo, Han Geuk

Publication type:

Article

Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0192667

By:

Liu, Chun;
Deb, Sanghamitra;
Ferreira, Vinicius S.;
Xu, Eric;
Baumgart, Tobias

Publication type:

Article

A Mechanism for Nerve Cell Excitation by Norepinephrine via Alpha-1 Adrenoceptors: Inhibition of Potassium M-Current.

Published in:

Cellular & Molecular Neurobiology, 2013, v. 33, n. 1, p. 1, doi. 10.1007/s10571-012-9870-y

By:

Filippov, Alexander;
Brown, David

Publication type:

Article

Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction.

Published in:

Nature Genetics, 2015, v. 47, n. 5, p. 528, doi. 10.1038/ng.3256

By:

Akizu, Naiara;
Ozgul, R Koksal;
Sagıroglu, Mahmut Samil;
Azam, Matloob;
Selim, Laila;
Mahmoud, Iman G;
Abdel-Hadi, Sawsan;
Badawy, Amera El;
Sadek, Abdelrahim A;
Mojahedi, Faezeh;
Kayserili, Hulya;
Masri, Amira;
Bastaki, Laila;
Müller, Ulrich;
Cantagrel, Vincent;
Desguerre, Isabelle;
Casanova, Jean-Laurent;
Dursun, Ali;
Gunel, Murat;
Gabriel, Stacey B

Publication type:

Article

CL316243 Induces Phosphatidylinositol 3,4,5-triphosphate Production in Rat Adipocytes in an Adenosine Deaminase-, Pertussis Toxin-, or Wortmannin-Sensitive Manner.

Published in:

Physiological Research, 2016, v. 65, n. 3, p. 543, doi. 10.33549/physiolres.933162

By:

OHSAKA, Y.;
NOMURA, Y.

Publication type:

Article

Research on drug resistance mechanism of trastuzumab caused by activation of the PI3K/Akt signaling pathway.

Published in:

Contemporary Oncology / Współczesna Onkologia, 2013, v. 17, n. 4, p. 363, doi. 10.5114/wo.2013.35292

By:

Xi Chen;
Han Wang;
Xue-nong Ou-yang;
Fang-wei Xie;
Jing-jing Wu

Publication type:

Article

Induction of H2AX phosphorylation in tumor cells by gossypol acetic acid is mediated by phosphatidylinositol 3-kinase (PI3K) family.

Published in:

Cancer Cell International, 2014, v. 14, n. 1, p. 184, doi. 10.1186/s12935-014-0141-5

By:

Zhong Guo;
Jin Zhao;
Lei Song;
Jian-Xiu Ma;
Chen-Jing Wang;
Shu-Yan Pei;
Chao Jiang;
Shang-Biao Li

Publication type:

Article

Wnt5a promotes migration of human osteosarcoma cells by triggering a phosphatidylinositol-3 kinase/Akt signals.

Published in:

Cancer Cell International, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1475-2867-14-15

By:

Ailiang Zhang;
Shuanghua He;
Xiaoliang Sun;
Lianghua Ding;
Xinnan Bao;
Neng Wang

Publication type:

Article

Glycerolipidome responses to freezingand chilling-induced injuries: examples in Arabidopsis and rice.

Published in:

BMC Plant Biology, 2016, v. 16, p. 1, doi. 10.1186/s12870-016-0758-8

By:

Guowei Zheng;
Lixia Li;
Weiqi Li

Publication type:

Article

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity.

Published in:

PLoS Pathogens, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.ppat.1002576

By:

Bianco, Annalisa;
Reghellin, Veronica;
Donnici, Lorena;
Fenu, Simone;
Alvarez, Reinaldo;
Baruffa, Chiara;
Peri, Francesco;
Pagani, Massimiliano;
Abrignani, Sergio;
Neddermann, Petra;
De Francesco, Raffaele

Publication type:

Article

Activation of the phosphatidylinositol 3-kinase/Akt pathway is involved in lipocalin-2-promoted human pulmonary artery smooth muscle cell proliferation.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 410, n. 1/2, p. 207, doi. 10.1007/s11010-015-2553-5

By:

Wang, Guoliang;
Ma, Ning;
Meng, Liukun;
Wei, Yingjie;
Gui, Jingang

Publication type:

Article

Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 402, n. 1/2, p. 225, doi. 10.1007/s11010-015-2330-5

By:

Piplani, Honit;
Vaish, Vivek;
Rana, Chandan;
Nehru, Bimla;
Sanyal, S.

Publication type:

Article

Piperine inhibits type II phosphatidylinositol 4-kinases: a key component in phosphoinositides turnover.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 393, n. 1/2, p. 9, doi. 10.1007/s11010-014-2041-3

By:

Bojjireddy, Naveen;
Sinha, Ranjeet;
Subrahmanyam, Gosukonda

Publication type:

Article

PIP3 but not PIP2 increases GLUT4 surface expression and glucose metabolism mediated by AKT/PKCζ/λ phosphorylation in 3T3L1 adipocytes.

Published in:

Molecular & Cellular Biochemistry, 2013, v. 381, n. 1/2, p. 291, doi. 10.1007/s11010-013-1714-7

By:

Manna, Prasenjit;
Jain, Sushil

Publication type:

Article

Features of the Phosphatidylinositol Cycle and its Role in Signal Transduction.

Published in:

2017

By:

Epand, Richard;
Epand, Richard M

Publication type:

journal article

Hydrocinnamic Acid Inhibits the Currents of WT and SQT3 Syndrome-Related Mutants of Kir2.1 Channel.

Published in:

2017

By:

Ren, Shuxi;
Pang, Chunli;
Huang, Yayue;
Xing, Chengfen;
Zhan, Yong;
An, Hailong

Publication type:

journal article

Phospholipid Composition and Electric Charge in Healthy and Cancerous Parts of Human Kidneys.

Published in:

Journal of Membrane Biology, 2013, v. 246, n. 5, p. 421, doi. 10.1007/s00232-013-9554-7

By:

Szachowicz-Petelska, Barbara;
Dobrzyńska, Izabela;
Skrodzka, Marta;
Darewicz, Barbara;
Figaszewski, Zbigniew;
Kudelski, Jacek

Publication type:

Article

Synergistic interplay of Gβγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity.

Published in:

Pflügers Archiv: European Journal of Physiology, 2017, v. 469, n. 2, p. 213, doi. 10.1007/s00424-016-1916-4

By:

Povstyan, Oleksandr;
Barrese, Vincenzo;
Stott, Jennifer;
Greenwood, Iain

Publication type:

Article

Inhibition of TREK-2 K channels by PI(4,5)P: an intrinsic mode of regulation by intracellular ATP via phosphatidylinositol kinase.

Published in:

Pflügers Archiv: European Journal of Physiology, 2016, v. 468, n. 8, p. 1389, doi. 10.1007/s00424-016-1847-0

By:

Woo, Joohan;
Shin, Dong;
Kim, Hyun;
Yoo, Hae;
Zhang, Yin-Hua;
Nam, Joo;
Kim, Woo;
Kim, Sung

Publication type:

Article

A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P.

Published in:

Pflügers Archiv: European Journal of Physiology, 2013, v. 465, n. 7, p. 945, doi. 10.1007/s00424-012-1199-3

By:

Telezhkin, Vsevolod;
Thomas, Alison;
Harmer, Stephen;
Tinker, Andrew;
Brown, David

Publication type:

Article

Capillary Inward-Rectifying K+ Crippled in a Mouse Model of Alzheimer's Disease: Phosphatidylinositol 4,5-Bisphosphate to the Rescue!

Published in:

Function, 2021, v. 2, n. 3, p. 1, doi. 10.1093/function/zqab017

By:

Jackson, William F.

Publication type:

Article

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils.

Published in:

Nature Immunology, 2012, v. 13, n. 4, p. 369, doi. 10.1038/ni.2234

By:

Honda, Fumiko;
Kano, Hirotsugu;
Kanegane, Hirokazu;
Nonoyama, Shigeaki;
Kim, Eun-Sung;
Lee, Sang-Kyou;
Takagi, Masatoshi;
Mizutani, Shuki;
Morio, Tomohiro

Publication type:

Article

Curcumin Protects Mice From Coxsackievirus B3-Induced Myocarditis by Inhibiting the Phosphatidylinositol 3 kinase/Akt/Nuclear Factor-κB Pathway.

Published in:

Journal of Cardiovascular Pharmacology & Therapeutics, 2013, v. 18, n. 6, p. 560, doi. 10.1177/1074248413503044

By:

Song, Yunxiao;
Ge, Wen;
Cai, HaiBing;
Zhang, Haichen

Publication type:

Article

Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate.

Published in:

Journal of Cell Biology, 2015, v. 209, n. 3, p. 435, doi. 10.1083/jcb.201409082

By:

Gerber, Pehuén Pereyra;
Cabrini, Mercedes;
Jancic, Carolina;
Paoletti, Luciano;
Banchio, Claudia;
von Bilderling, Catalina;
Sigaut, Lorena;
Pietrasanta, Lía I.;
Duette, Gabriel;
Freed, Eric O.;
de Saint Basile, Genevieve;
Ferreira Moita, Catarina;
Ferreira Moita, Luis;
Amigorena, Sebastian;
Benaroch, Philippe;
Geffner, Jorge;
Ostrowski, Matías

Publication type:

Article

PIP3-dependent macropinocytosis is incompatible with chemotaxis.

Published in:

Journal of Cell Biology, 2014, v. 204, n. 4, p. 497, doi. 10.1083/jcb.201309081

By:

Veltman, Douwe M.;
Lemieux, Michael G.;
Knecht, David A.;
Insall, Robert H.

Publication type:

Article

DNA structure-specific priming of ATR activation by DNA-PKcs.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 3, p. 421, doi. 10.1083/jcb.201304139

By:

Vidal-Eychenié, Sophie;
Décaillet, Chantal;
Basbous, Jihane;
Constantinou, Angelos

Publication type:

Article

Clathrin and AP2 are required for Ptdlns(4,5)P2- mediated formation of LRP6 signalosomes.

Published in:

Journal of Cell Biology, 2013, v. 200, n. 4, p. 419, doi. 10.1083/jcb.201206096

By:

Kim, Ingyu;
Pan, Weijun;
Jones, Sara A.;
Zhang, Youxin;
Zhuang, Xiaowei;
Wu, Dianqing

Publication type:

Article