Works matching DE "PHOSPHATIDYLINOSITOL 3-kinases"
Results: 2359
ASF1B promotes gastric cancer progression by modulating H2AC20 and activating PI3K/AKT and ERK1/2 pathways.
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- Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1533257
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- Article
In silico discovery of a novel potential allosteric PI3Kα inhibitor incorporating 2-oxopropyl urea targeting head and neck squamous cell carcinoma.
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- BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01420-6
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- Article
A narrative review of autophagy in migraine.
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- Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1500189
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- Article
Antidiabetic Effects of Quercetin and Silk Sericin in Attenuating Dysregulation of Hepatic Gluconeogenesis in Diabetic Rats Through Potential Modulation of PI3K/Akt/FOXO1 Signaling: In Vivo and In Silico Studies.
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- Journal of Xenobiotics, 2025, v. 15, n. 1, p. 16, doi. 10.3390/jox15010016
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- Article
Network Pharmacology to Unveil the Mechanism of Berberine in the Treatment of Streptococcus suis Meningitis in Humans and Pigs.
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- Toxics, 2025, v. 13, n. 2, p. 138, doi. 10.3390/toxics13020138
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- Article
NRBF2 plays a crucial role in the acquisition process of learning and memory, independent of the Vps34 complex.
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- Frontiers in Behavioral Neuroscience, 2025, p. 1, doi. 10.3389/fnbeh.2025.1529522
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- Article
Enhanced Anti-Cancer Potential: Investigating the Combined Effects with Coriolus versicolor Extract and Phosphatidylinositol 3-Kinase Inhibitor (LY294002) In Vitro.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1556, doi. 10.3390/ijms26041556
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- Article
Divide and Conquer—Targeted Therapy for Triple-Negative Breast Cancer.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1396, doi. 10.3390/ijms26041396
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- Article
Glutamatergic argonaute2 promotes the formation of the neurovascular unit in mice.
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- Science Signaling, 2025, v. 18, n. 875, p. 1, doi. 10.1126/scisignal.adl6745
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- Article
In Situ Reprogramming of Tumor‐Associated Macrophages with Internally and Externally Engineered Exosomes.
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- Angewandte Chemie, 2023, v. 135, n. 11, p. 1, doi. 10.1002/ange.202217089
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- Article
FGF20‐FGFR1 signaling through MAPK and PI3K controls sensory progenitor differentiation in the organ of Corti.
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- Developmental Dynamics, 2021, v. 250, n. 2, p. 134, doi. 10.1002/dvdy.231
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- Article
Increased visfatin expression is associated with nuclear factor-kappa B and phosphatidylinositol 3-kinase in periodontal inflammation.
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- Clinical Oral Investigations, 2017, v. 21, n. 4, p. 1113, doi. 10.1007/s00784-016-1871-7
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- Article
In silico development and experimental validation of a novel 7-gene signature based on PI3K pathway-related genes in bladder cancer.
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- Functional & Integrative Genomics, 2022, v. 22, n. 5, p. 797, doi. 10.1007/s10142-022-00884-2
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- Article
Phytosphingosine-1-phosphate represses the hydrogen peroxide-induced activation of c-Jun N-terminal kinase in human dermal fibroblasts through the phosphatidylinositol 3-kinase/Akt pathway.
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- Archives of Dermatological Research, 2012, v. 304, n. 8, p. 673, doi. 10.1007/s00403-012-1241-5
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- Article
Tissue Transglutaminase Impairs HTR-8/SVneo Trophoblast Cell Invasion via the PI3K/AKT Signaling Pathway.
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- Gynecologic & Obstetric Investigation, 2021, v. 86, n. 3, p. 264, doi. 10.1159/000515086
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- Article
MicroRNA-301a Promotes Cell Proliferation and Resistance to Apoptosis through PTEN/PI3K/Akt Signaling Pathway in Human Ovarian Cancer.
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- Gynecologic & Obstetric Investigation, 2021, v. 86, n. 1-2, p. 108, doi. 10.1159/000513070
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- Article
The interplay of ROS and the PI3K/Akt pathway in autophagy regulation.
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- Biotechnology & Applied Biochemistry, 2022, v. 69, n. 1, p. 248, doi. 10.1002/bab.2104
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- Article
Fibroblast growth factors: properties, biosynthesis, biological functions, therapeutic applications and engineering.
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- International Journal of Medical Biochemistry, 2024, v. 7, n. 2, p. 114, doi. 10.14744/ijmb.2024.16768
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- Article
Regulation of lymphoma in vitro by CLP36 through the PI3K/AKT/CREB signaling pathway.
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- PeerJ, 2024, p. 1, doi. 10.7717/peerj.18693
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- Article
Differentially expressed genes in orbital adipose/connective tissue of thyroid-associated orbitopathy.
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- PeerJ, 2023, p. 1, doi. 10.7717/peerj.16569
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- Article
miR-378 associated with proliferation, migration and apoptosis properties in A549 cells and targeted NPNT in COPD.
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- PeerJ, 2022, p. 1, doi. 10.7717/peerj.14062
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- Article
Active ingredients and molecular targets of Taraxacum mongolicum against hepatocellular carcinoma: network pharmacology, molecular docking, and molecular dynamics simulation analysis.
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- PeerJ, 2022, p. 1, doi. 10.7717/peerj.13737
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- Article
Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy.
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- JNCI: Journal of the National Cancer Institute, 2015, v. 107, n. 3, p. 1, doi. 10.1093/jnci/dju502
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- Article
A Small Cog in a Big Wheel: PIK3CA Mutations in Colorectal Cancer.
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- JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 23, p. 1775, doi. 10.1093/jnci/djt330
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- Article
Predictive and Prognostic Analysis of PIK3CA Mutation in Stage III Colon Cancer Intergroup Trial.
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- JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 23, p. 1789, doi. 10.1093/jnci/djt298
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- Article
Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK).
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2237209
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- Article
Design, synthesis and evaluation of 2, 6, 8-substituted Imidazopyridine derivatives as potent PI3Kα inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2022.2155638
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- Article
Design, synthesis, and biological evaluation of new thieno[2,3-d] pyrimidine derivatives as targeted therapy for PI3K with molecular modelling study.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 315, doi. 10.1080/14756366.2021.2010729
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- Article
Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 651, doi. 10.1080/14756366.2018.1444608
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- Article
Tumour suppressor PTEN enhanced enzyme activity of GPx, SOD and catalase by suppression of PI3K/AKT pathway in non-small cell lung cancer cell lines.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 3, p. 539, doi. 10.3109/14756366.2011.654114
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- Article
A review of recombinant HER3 affibodies with an effective diagnostic view of cancer cells.
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- Journal of Drug Targeting, 2025, v. 33, n. 3, p. 316, doi. 10.1080/1061186X.2024.2420202
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- Article
Cell type-specific NRBF2 orchestrates autophagic flux and adult hippocampal neurogenesis in chronic stress-induced depression.
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- Cell Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41421-023-00583-7
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- Article
Spatiotemporal regulation of insulin signaling by liquid–liquid phase separation.
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- Cell Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41421-022-00430-1
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- Article
Caloric restriction can improve learning ability in C57/BL mice via regulation of the insulin-PI3K/Akt signaling pathway.
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- Neurological Sciences, 2014, v. 35, n. 9, p. 1381, doi. 10.1007/s10072-014-1717-5
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- Article
Remifentanil postconditioning improves global cerebral ischemia-induced spatial learning and memory deficit in rats via inhibition of neuronal apoptosis through the PI3K signaling pathway.
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- Neurological Sciences, 2013, v. 34, n. 11, p. 1955, doi. 10.1007/s10072-013-1419-4
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- Article
Anti-obesity molecules of natural origin.
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- Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2022, v. 68, p. 15, doi. 10.33320/maced.pharm.bull.2022.68.04.002
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- Article
复方斑蝥胶囊联合戈舍瑞林对绝经前乳腺癌患者 PI3K/Akt 信号通路、凋亡因子及短期预后的影响.
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- Progress in Modern Biomedicine, 2024, v. 24, n. 24, p. 4788, doi. 10.13241/j.cnki.pmb.2024.24.047
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- Article
利拉鲁肽改善 SH-SY5Y 细胞氧化应激, 线粒体功能障碍, 自噬损伤的机制研究.
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- Progress in Modern Biomedicine, 2024, v. 24, n. 23, p. 4408, doi. 10.13241/j.cnki.pmb.2024.23.002
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- Article
肥胖型多囊卵巢综合征患者外周血淋巴细胞 miR-27a、miR-141 与 PI3K/AKT 信号通路的相关性分析.
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- Progress in Modern Biomedicine, 2024, v. 24, n. 22, p. 4291, doi. 10.13241/j.cnki.pmb.2024.22.026
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- Article
血清 miR-26a、miR-130a 与老年急性脑梗死患者 PI3K/Akt 信号 通路和预后的关系研究.
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- Progress in Modern Biomedicine, 2023, v. 23, n. 14, p. 2770, doi. 10.13241/j.cnki.pmb.2023.14.033
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The In Vitro Immunomodulatory Effects of Gold Nanocomplex on THP-1-Derived Macrophages.
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- 2022
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- journal article
The In Vitro Immunomodulatory Effects of Gold Nanocomplex on THP-1-Derived Macrophages.
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- Journal of Immunology Research, 2022, p. 1, doi. 10.1155/2022/6031776
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- Article
加味涤痰汤对慢性间歇低氧大鼠心肌铁死亡的影响.
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- Journal of Beijing University of Traditional Chinese Medicine, 2024, v. 47, n. 10, p. 1427, doi. 10.3969/j.issn.1006-2157.2024.10.013
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- Article
The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells.
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- Journal of Diabetes Research, 2015, v. 2015, p. 1, doi. 10.1155/2015/920280
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- Article
Phosphatidylinositol 4,5-bisphosphate (PIP<sub>2</sub>) modulates afterhyperpolarizations in oxytocin neurons of the supraoptic nucleus.
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- Journal of Physiology, 2017, v. 595, n. 14, p. 4927, doi. 10.1113/JP274219
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- Article
Translating Research Into Clinical Practice In Chronic Colitis To Colorectal Cancer Model.
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- Malaysian Journal of Medicine & Health Sciences, 2022, v. 18, p. 14
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- Article
Periostin, a matricellular protein, accelerates cutaneous wound repair by activating dermal fibroblasts.
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- Experimental Dermatology, 2012, v. 21, n. 5, p. 331, doi. 10.1111/j.1600-0625.2012.01454.x
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- Article
Determining drug dose in the era of targeted therapies: playing it (un)safe?
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- Blood Cancer Journal, 2022, v. 12, n. 8, p. 1, doi. 10.1038/s41408-022-00720-7
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- Article
Icaritin alleviates motor impairment and osteoporosis in Parkinson's disease mice via the ER-PI3K/Akt pathway.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87429-2
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- Article
Scalable preparation of furanosteroidal viridin, β-viridin and viridiol from Trichoderma virens.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87070-z
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- Article