Works matching DE "PHARMACEUTICAL chemistry"

Results: 5000

Dual Photoredox/Copper‐Catalyzed 1,2‐Diphosphorothiolation of Alkenes with P(O)SH Compounds to Access Vicinal Bisphosphorothioates.

Published in:

Chinese Journal of Chemistry, 2025, v. 43, n. 16, p. 1977, doi. 10.1002/cjoc.70089

By:

Zhang, Pengbo;
Wang, Longyu;
Guo, Xinyi;
Liu, Yaxin;
Yang, Qihang;
Gao, Xia

Publication type:

Article

Natural Coumarin‐Hybridized Thiazolylbenzonitriles as New Structural Scaffolds to Exert Potentially Multitargeting Supramolecular Antibacterial Behavior.

Published in:

Chinese Journal of Chemistry, 2025, v. 43, n. 16, p. 1909, doi. 10.1002/cjoc.70072

By:

Li, Qian‐Yue;
Zeng, Chun‐Mei;
Chen, Yao;
Ahmad, Nisar;
Zhang, Shao‐Lin;
Zhou, Cheng‐He

Publication type:

Article

A piperidinyl indole derivative, potential complement factor B inhibitor, plays a renoprotective role in diabetic nephropathy.

Published in:

Diabetic Medicine, 2025, v. 42, n. 8, p. 1, doi. 10.1111/dme.70092

By:

Li, Zi‐Han;
Sun, Zi‐Jun;
Chang, Dong‐Yuan;
Zhao, Ming‐Hui;
Tang, Sydney C. W.;
Chen, Min

Publication type:

Article

Multicolored sequential resonance energy transfer for detection of simultaneous ligand binding at G protein-coupled receptors.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61690-5

By:

Valentini, Alice;
Dibnah, Bethany;
Ciba, Marija;
Duncan, Elaine M.;
Manandhar, Asmita;
Strellis, Bethany;
Vita, Luca;
Lucianno, Olivia;
Massey, Conor;
Coe, Sophie;
Ulven, Trond;
Hudson, Brian D.;
Rexen Ulven, Elisabeth

Publication type:

Article

Cartilage-protective effects of lopinavir/ritonavir: in vitro and in silico exploration of the HIF-1α/SOX9/IL-1β pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-06068-5

By:

Ozbek, Hanefi;
Yilmaz, Ibrahim;
Akyuz, Aslı;
Pehlivanoglu, Suray;
Sirin, Duygu Yasar;
Albayrak, Mehmet;
Yilmaz, Omer Faruk

Publication type:

Article

Photoinduced Copper‐Mediated Difluoroalkylation of Arylsulfonium Salts with XCF2COR.

Published in:

Chemistry - An Asian Journal, 2025, v. 20, n. 13, p. 1, doi. 10.1002/asia.202500331

By:

Xia, Fang;
Wang, Yan‐Hao;
Ding, Xing‐Yu;
Zhang, Cheng‐Pan

Publication type:

Article

Catalytic Activity Alternation of an Artificial Metalloenzyme by Switchable Binding to the Proteins.

Published in:

ChemCatChem, 2025, v. 17, n. 13, p. 1, doi. 10.1002/cctc.202500154

By:

Muguruma, Kyohei;
Imai, Kyosuke;
Tanaka, Katsunori

Publication type:

Article

Integrated Multi-Omics Analysis Reveals the Regulatory Mechanism of Peanut Skin Procyanidins on Lipid Metabolism in High-Fat-Diet-Induced Obese Mice.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2228, doi. 10.3390/nu17132228

By:

Shen, Jinxin;
Zhou, Yi;
Yang, Daijun;
Liu, Ruonan;
Zhu, Xiaoling;
Liu, Rui

Publication type:

Article

Postbiotics Formulation and Therapeutic Effect in Inflammation: A Systematic Review.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2187, doi. 10.3390/nu17132187

By:

Zdybel, Kinga;
Śliwka, Angelika;
Polak-Berecka, Magdalena;
Polak, Paweł;
Waśko, Adam

Publication type:

Article

Hydrazides as Powerful Tools in Medicinal Chemistry: Synthesis, Reactivity, and Biological Applications.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2852, doi. 10.3390/molecules30132852

By:

Teixeira, Sofia;
Castanheira, Elisabete M. S.;
Carvalho, M. Alice

Publication type:

Article

Synthesis of Novel 7-Phenyl-2,3-Dihydropyrrolo[2,1- b ]Quinazolin-9(1 H)-ones as Cholinesterase Inhibitors Targeting Alzheimer's Disease Through Suzuki–Miyaura Cross-Coupling Reaction.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2791, doi. 10.3390/molecules30132791

By:

Turgunov, Davron;
Nie, Lifei;
Nasrullaev, Azizbek;
Murtazaeva, Zarifa;
Wang, Bianlin;
Kholmurodova, Dilafruz;
Kuryazov, Rustamkhon;
Zhao, Jiangyu;
Bozorov, Khurshed;
Aisa, Haji Akber

Publication type:

Article

Synthesis and In Vitro Pharmacological Evaluation of 5,8-Dideaza Analogs of Methotrexate.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2772, doi. 10.3390/molecules30132772

By:

Abellán-Flos, Marta;
Skarbek, Charles;
Gibbons, Dáire J.;
Rascol, Estelle;
García, Ainhoa;
Labruère, Raphaël

Publication type:

Article

Dimethyl Isosorbide: An Innovative Bio-Renewable Solvent for Sustainable Chromatographic Applications.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2713, doi. 10.3390/molecules30132713

By:

Damjanoska, Aleksandra;
Mitreska, Kristina;
Petrova, Matilda;
Acevska, Jelena;
Brezovska, Katerina;
Nakov, Natalija

Publication type:

Article

Hybrid Molecules with Purine and Pyrimidine Derivatives for Antitumor Therapy: News, Perspectives, and Future Directions.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2707, doi. 10.3390/molecules30132707

By:

Iacob, Simona;
Stefan, Claudia-Simona;
Nechita, Aurel;
Matei, Madalina-Nicoleta;
Lisa, Elena-Lacramioara;
Tutunaru, Dana;
Fulga, Iuliu;
Fulga, Ana;
Cristea, Alina-Georgiana;
Dragostin, Oana-Maria

Publication type:

Article

Molecular Hybrids of Thiazolidinone: Bridging Redox Modulation and Cancer Therapy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6529, doi. 10.3390/ijms26136529

By:

Zahrani, Nourah A. Al;
Alshabibi, Manal A.;
Bakr, Abrar A.;
Almughem, Fahad A.;
Alshehri, Abdullah A.;
Al-Ghamdi, Huda A.;
Tawfik, Essam A.;
Damiati, Laila A.

Publication type:

Article

Diammonium Glycyrrhizinate Exerts Broad-Spectrum Antiviral Activity Against Human Coronaviruses by Interrupting Spike-Mediated Cellular Entry.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6334, doi. 10.3390/ijms26136334

By:

Wu, Shuo;
Yang, Ge;
Wang, Kun;
Yan, Haiyan;
Wang, Huiqiang;
Li, Xingqiong;
Qiao, Lijun;
Wu, Mengyuan;
Wang, Ya;
Jiang, Jian-Dong;
Li, Yuhuan

Publication type:

Article

Synthesis and Transformation of Tricyclic KYNA Derivatives.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6248, doi. 10.3390/ijms26136248

By:

Sárik, Julián Robin;
Szatmári, István;
Lőrinczi, Bálint

Publication type:

Article

New Quipazine Derivatives Active Against Drug-Resistant Oncogenic Helicobacter pylori Strains with Biofilm.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 5997, doi. 10.3390/ijms26135997

By:

Grychowska, Katarzyna;
Klesiewicz, Karolina;
Pęgiel, Joanna;
Kuziak, Agata;
Skiba-Kurek, Iwona;
Canale, Vittorio;
Krzysiek-Mączka, Gracjana;
Ptak-Belowska, Agata;
Piska, Kamil;
Koczurkiewicz-Adamczyk, Paulina;
Krzyżek, Paweł;
Brzozowski, Tomasz;
Zajdel, Paweł;
Karczewska, Elżbieta

Publication type:

Article

Deguelin's Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1571452

By:

Jiang, Wenjie;
Zeng, Jing;
Guo, Li;
Shi, Jianyou;
Lei, Yang

Publication type:

Article

Integrative bioinformatics and machine learning approaches reveal oxidative stress and glucose metabolism related genes as therapeutic targets and drug candidates in Alzheimer's disease.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1572468

By:

Noor, Fatima;
Aslam, Sidra;
Piras, Ignazio S.;
Tremblay, Cecilia;
Beach, Thomas G.;
Serrano, Geidy E.

Publication type:

Article

Challenges to Establishing Pharmaceutical Medicine as a Profession: Needs for Professional Identity and a Career Pathway: Role of Education and Training.

Published in:

Pharmaceutical Medicine, 2025, v. 39, n. 4, p. 235, doi. 10.1007/s40290-025-00559-w

By:

Silva, Honorio;
Baroutsou, Varvara;
Criscuolo, Domenico;
Guptha, Soneil;
Jurczynska, Anna;
Kerpel-Fronius, Sandor;
Klech, Heinrich;
Klingmann, Ingrid

Publication type:

Article

Evaluation of the antibacterial efficacy of combinations of Garcinia mangostana, Curcuma comosa, and Acanthus ebracteatus for acne vulgaris treatment: in Silico and in vitro validation.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04997-6

By:

Eawsakul, Komgrit;
Bunluepuech, Kingkan;
Wisessombat, Sueptrakool

Publication type:

Article

Treatment of pre-extensively drug-resistant tuberculosis in a 4-month-old infant using a regimen of bedaquiline, delamanid, and contezolid.

Published in:

European Journal of Clinical Microbiology & Infectious Diseases, 2025, v. 44, n. 7, p. 1729, doi. 10.1007/s10096-025-05128-2

By:

Ding, Wenrui;
Shen, Lingyun;
Li, Ruonan;
Yang, Xiaotao;
Wang, Yanchun;
Luo, Yonghan

Publication type:

Article

Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01164-4

By:

Bian, Yanqin;
Li, Fang;
A, Xinyu;
Xiang, Zheng;
Ma, Nanshan;
Wang, Jianye;
Cao, Boran;
Xin, Pengfei;
Cheng, Xuan;
Liu, Chang;
Xiang, Bei;
Shen, Jun;
Lu, Qigui;
Xiao, Lianbo

Publication type:

Article

Rh(III)‐Catalyzed Cascade [3 + 3] Spiroannulation of N‐Acyl Ketimines with Iodonium Ylides: Access to Spiro‐N,O‐Ketals.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 21, p. 1, doi. 10.1002/ejoc.202500155

By:

Wen, Jiaojiao;
Zhang, Xia;
Pi, Chao;
Wu, Yangjie;
Cui, Xiuling

Publication type:

Article

On the Synthesis of [1,3]Azaphospholo[4,5‐f]quino(xa)lines and 2,3‐Dihydro‐[1,3]azaphospholo[4,5‐f]quino(xa)line 1‐oxides.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 17, p. 1, doi. 10.1002/ejoc.202500080

By:

Dridi, Mohamed Ali;
Hasyeoui, Mohamed;
Lassagne, Frédéric;
Erb, William;
Piroud, Charline;
Robert, Thomas;
Bach, Stéphane;
Samarat, Ali;
Touil, Soufiane;
Mongin, Florence

Publication type:

Article

Multigram Synthesis of 3‐Azabicyclo[3.1.1]heptane Derivatives Including Bicyclic Thalidomide Analogs.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 17, p. 1, doi. 10.1002/ejoc.202400938

By:

Lysenko, Viacheslav;
Portiankin, Anton;
Shyshlyk, Oleh;
Savchenko, Timur;
Nazarenko, Kostiantyn;
Kostyuk, Alexander;
Golovchenko, Oleksandr V.;
Brovarets, Volodymyr S.;
Grygorenko, Oleksandr O.

Publication type:

Article

Application of Microwave Ablation Combined With Chai Hu Qing Gan Tang in the Treatment of Idiopathic Granulomatous Mastitis.

Published in:

Breast Journal, 2025, v. 2025, p. 1, doi. 10.1155/tbj/2731494

By:

Li, Hang;
Li, Bing;
Chen, Haiying;
Liu, Xiaoli;
Wang, Hongling;
Zhang, Guoliang;
Wani, Imtiaz

Publication type:

Article

Unveiling the Therapeutic Potential of Piper chaba Hunter: Computational Approaches Shed Light on Targeting Proteins in Alzheimer's Disease.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/8892801

By:

Rahi, Md. Sifat;
Rahman, Md. Shahedur;
Meem, Rima Islam;
Shimul, Md. Ebrahim Khalil;
Farnaj, Nahid;
Kabir, Md. Humaun;
Ahmed, Fee Faysal;
Parvez, Md. Anowar Khasru;
Huq, Md. Amdadul;
Kabir, Tabassum;
Harrath, Abdel Halim;
Hasan, Mahadi;
Rahman, Md. Ataur;
Siddique, Muhammad Hussnain

Publication type:

Article

Aptamer‐RIBOTAC Strategy Enabling Tumor‐Specific Targeted Degradation of MicroRNA for Precise Cancer Therapy.

Published in:

Small Methods, 2025, v. 9, n. 6, p. 1, doi. 10.1002/smtd.202400349

By:

Fang, Yuan;
Wu, Qiuyue;
Wang, Feiyu;
Liu, Ye;
Zhang, Huimin;
Yang, Chaoyong;
Zhu, Zhi

Publication type:

Article

Peptide‐Triazolobenzodiazepine Hybrids: A Catalyst‐Free on‐Resin Strategy to Build Complex Therapeutic Motifs Into Peptides.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 34, p. 1, doi. 10.1002/chem.202500836

By:

Kamble, Sandip Sushila Mohan;
Bodake, Supriya Mahadev;
Marelli, Udaya Kiran

Publication type:

Article

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202425206

By:

Woodland, John G.;
Coertzen, Dina;
Wicht, Kathryn J.;
Hidalgo, Virginia Franco;
Pasaje, Charisse Flerida A.;
Godoy, Luiz C.;
Qahash, Tarrick;
Mmonwa, Mmakwena M.;
Dziwornu, Godwin A.;
Wambua, Lynn;
Harries, Sarah;
Korkor, Constance M.;
Njoroge, Mathew;
Krugmann, Liezl;
Taylor, Dale;
Leshabane, Meta;
Langeveld, Henrico;
Rabie, Tayla;
Reader, Janette;
van der Watt, Mariëtte

Publication type:

Article

Herbosomal Sunscreen Lotion Shows Promising Sun Protection and Skin Benefits.

Published in:: Indian Practitioner, 2025, v. 78, n. 6, p. 53
Publication type:: Article

Purposeful Drug Repurposing.

Published in:

2025

By:

Nagele, Peter;
Conway, Charles R.;
Zorumski, Charles F.

Publication type:

Opinion

A survey of availability, price, and affordability of innovative negotiated anticancer medicines: a retrospective study in Jiangsu Province, eastern China.

Published in:

BMC Public Health, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12889-025-23570-x

By:

Ma, Rui;
Liu, Yanyan;
Ding, Baolong;
Sun, Yuyang;
Yao, Hongting;
Yu, Man;
Wang, Xiaoye;
Zhang, Lingli;
Li, Xin

Publication type:

Article

Perceptions of Chinese Pharmacy Postgraduates Regarding Academic Research and Academic Misconduct: A Qualitative Study.

Published in:

SAGE Open, 2025, v. 15, n. 2, p. 1, doi. 10.1177/21582440251340475

By:

Cheng, Meili;
Zhang, Shuai;
Zhao, Chunhua;
Shen, Xiuxiu;
Wu, Di

Publication type:

Article

The Synthesis of Aryl‐β‐C‐Glycosides from Native Saccharides.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 37, p. 1, doi. 10.1002/chem.202501216

By:

Bunt, Daan V.;
van Looij, Joey;
Lenze, Alexander F.;
Štuhec, Viktor;
Witte, Martin D.;
Minnaard, Adriaan J.

Publication type:

Article

Treatment of rheumatoid arthritis by Rhododendron molle G. Don: the anti-inflammatory mechanism of its extract was elucidated by network analysis combined with experimental verification.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04982-z

By:

Mei, Wenya;
Yu, Junbao;
Zhu, Jiayuan;
Deng, Ting;
Deng, Yasi;
Tong, Qiaozhen;
Liu, Xiangdan;
Yu, Huanghe;
Zhou, Ribao;
Liu, Xiaorong

Publication type:

Article

Bioprospection of indigenous herbal formulations for diabetes care: in vitro, network pharmacology, and molecular dynamics studies.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04980-1

By:

Ojo, Oluwafemi Adeleke;
Ogunlakin, Akingbolabo Daniel;
Ajayi-Odoko, Omolola Adenike;
Gyebi, Gideon Ampoma;
Ayokunle, Damilare IyinKristi;
Olanrewaju, Adesoji Alani;
Agbeye, Oluwatobi Deborah;
Ogunwale, Emmanuel Tope;
Adeyemi, Oluyomi Stephen

Publication type:

Article

Condition-controlled divergent trifluoroalkylation: a diversity-oriented synthesis strategy for efficient construction of CF3-decorated carbazole libraries.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01536-9

By:

Chen, Peng;
Yin, Jin;
Tang, You-Hui;
Li, Meng-Yuan;
Jiang, Yi-Jun

Publication type:

Article

Unlocking Indazole Synthesis from α‐Diazo‐β‐Ketoesters via Aryne Trapping: A Streamlined Approach.

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 25, p. 1, doi. 10.1002/ejoc.202500296

By:

Guha, Souvik;
Crochet, Aurélien;
Sukumar, Thillaiarasi;
Ravva, Mahesh Kumar;
Sen, Subhabrata;
Gremaud, Ludovic

Publication type:

Article

DISINFECTANT SUSCEPTIBILITY OF BACTERIAL ISOLATES FROM SURFACES IN THE FACULTY OF PHARMACEUTICAL SCIENCES BAYERO UNIVERSITY KANO.

Published in:

Bayero Journal of Pure & Applied Sciences, 2024, v. 15, p. 27, doi. 10.4314/bajopas.v15i1.5S

By:

Kibiya, H. Y.;
Mohammed, A.

Publication type:

Article

Glucosamine activates intestinal P-glycoprotein inhibiting drug absorption.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61437-2

By:

Wu, Qinghua;
Wang, Qing;
Luo, Xiaohong;
Jin, Peng;
Jin, Ming;
Hussain, Sajid;
Qi, Yiming;
Mo, Junfeng;
Yu, Yinglan;
Shao, Hao;
Luo, Lei

Publication type:

Article

Non-C2 symmetric chiral ligand dictating allyl-allyl coupling.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59902-z

By:

Xu, Zhengshuai;
Qian, Hui;
Ma, Shengming

Publication type:

Article

Integrating network pharmacology and multi-omics in a systems approach: a mechanism study of Jinhong tablets against chronic superficial gastritis.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01138-6

By:

Xiao, Lihao;
Zhang, Tingyu;
Liu, Yun;
Sutcharitchan, Chayanis;
Liu, Qingyuan;
Fan, Xiaoxue;
Feng, Jian;
Gao, Huifang;
Li, Shao;
Zhang, Tong

Publication type:

Article

Multi-omics and network pharmacology reveal Huayu-Tongbi decoction reduced arthritis-related bone erosion.

Published in:

Chinese Medicine, 2025, v. 20, p. 1, doi. 10.1186/s13020-025-01159-1

By:

Chen, Bozhen;
Yang, Lu;
Wang, Houchun;
Yu, Peng;
Ma, Mengyang;
Chen, Meiqi;
Zhou, Yingyan;
Wu, Jiaqi;
Liang, Huasheng;
Wang, Maojie;
Huang, Runyue;
He, Yiting;
Huang, Qingchun;
He, Xiaohong

Publication type:

Article

Decoding the anti-thrombotic effects of leonurine: a multimodal approach combining TCM repositioning and mTOR signaling.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01160-8

By:

Dong, Xin;
Jia, Shuaibing;
Zhang, Leifeng;
Liang, Yong;
Zhang, Jianhua;
Zhu, Yi Zhun

Publication type:

Article

Letter from the Editor-in-Chief.

Published in:

Jordan Journal of Pharmaceutical Sciences, 2025, v. 18, n. 2, p. x

By:

Alabbadi, Ibrahim

Publication type:

Article

INTRODUCTION.

Published in:

Jordan Journal of Pharmaceutical Sciences, 2025, v. 18, n. 2, p. ix

By:

Alabbadi, Ibrahim

Publication type:

Article

Small-molecule inhibitors in psoriasis: medicinal chemistry insights.

Published in:

Expert Opinion on Drug Discovery, 2025, v. 20, n. 7, p. 891, doi. 10.1080/17460441.2025.2507767

By:

Mao, Tianqi;
Gao, Jingjing;
Jia, Jie;
Zou, Fengxia;
Wang, Kai;
Wang, Yiyun;
Li, Jiyu;
Shen, Tao;
Li, Huanqiu

Publication type:

Article