Works about PGC-1 protein

Results: 314

PGC-1 alpha overexpression in the skeletal muscle results in a metabolically active microbiome which is independent of redox signaling.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-05594-w

By:

Koltai, Erika;
Mozaffaritabar, Soroosh;
Zhou, Lei;
Kolonics, Attila;
Koike, Atsuko;
Tanisawa, Kumpei;
Park, Jonguk;
Torma, Ferenc;
Radak, Zsolt

Publication type:

Article

Exploring possible hub genes of metabolic syndrome and type 2 diabetes mellitus: a systematic network biology study.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-95439-3

By:

Runthala, Ashish;
Vulichi, Srinivasa R.;
Kosanam, Sreya;
Pasupula, Rajeshwari;
Ramakrishna, Kakarla;
Sutradhar, Monoj;
Narayan, Kumar Pranav

Publication type:

Article

Fetal circulating human resistin increases in diabetes during pregnancy and impairs placental mitochondrial biogenesis.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00205-y

By:

Jiang, Shaoning;
Teague, April M.;
Tryggestad, Jeanie B.;
Lyons, Timothy J.;
Chernausek, Steven D.

Publication type:

Article

Protein kinase C beta relieves autism‐like behavior in EN2 knockout mice via upregulation of the FTO/PGC‐1α/UCP1 axis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 1, p. 1, doi. 10.1002/jbt.23236

By:

Song, Xingyu;
Hu, Qibo;
Xu, Xiaoheng;
Pan, Wei

Publication type:

Article

Molecular regulation of skeletal muscle mitochondrial biogenesis following blood flow-restricted aerobic exercise: a call to action.

Published in:

2021

By:

Preobrazenski, Nicholas;
Islam, Hashim;
Gurd, Brendon J.

Publication type:

journal article

PGC-1α alternative promoter (Exon 1b) controls augmentation of total PGC-1α gene expression in response to cold water immersion and low glycogen availability.

Published in:

European Journal of Applied Physiology, 2020, v. 120, n. 11, p. 2487, doi. 10.1007/s00421-020-04467-6

By:

Allan, R.;
Morton, J. P.;
Close, G. L.;
Drust, B.;
Gregson, W.;
Sharples, A. P.

Publication type:

Article

Mitochondrial health and muscle plasticity after spinal cord injury.

Published in:

2019

By:

Gorgey, Ashraf S.;
Witt, Oksana;
O'Brien, Laura;
Cardozo, Christopher;
Chen, Qun;
Lesnefsky, Edward J.;
Graham, Zachary A.

Publication type:

journal article

Nanoparticle-mediated targeting of PGC-1α reveals critical metabolic pathways in bladder cancer metastasis.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08174-w

By:

Liu, Zhenghua;
Xin, Peng;
Wu, Weiwei;
Jin, Mingyue;
Du, Yang;
Jiang, Yuanjun;
Liu, Tao;
Zhang, Hao

Publication type:

Article

Biochemical Adaptations in a Slow and a Fast Plantarflexor Muscle of Rats Housed in Small Cages.

Published in:

Aerospace Medicine & Human Performance, 2016, v. 87, n. 5, p. 443, doi. 10.3357/AMHP.4436.2016

By:

Takemura, Ai;
Roy, Roland R.;
Edgerton, V. Reggie;
Ishihara, Akihiko

Publication type:

Article

Long-term dietary resveratrol supplementation decreased serum lipids levels, improved intramuscular fat content, and changed the expression of several lipid metabolism-related miRNAs and genes in growing-finishing pigs.

Published in:

Journal of Animal Science, 2019, v. 97, n. 4, p. 1745, doi. 10.1093/jas/skz057

By:

Zhang, Hengzhi Z;
Chen, Daiwen W;
He, Jun;
Zheng, Ping;
Yu, Jie;
Mao, Xiangbing B;
Huang, Zhiqing Q;
Luo, Yuheng H;
Luo, Junqiu Q;
Yu, Bing

Publication type:

Article

Bta-miR-130a regulates the biosynthesis of bovine milk fat by targeting peroxisome proliferator-activated receptor gamma.

Published in:

Journal of Animal Science, 2017, v. 95, n. 7, p. 2898, doi. 10.2527/jas.2017.1504

By:

Yang, W. C.;
Guo, W. L.;
Zan, L. S.;
Wang, Y. N.;
Tang, K. Q.

Publication type:

Article

Mechanisms of Resveratrol-Induced Inhibition of Clonal Expansion and Terminal Adipogenic Differentiation in 3T3-L1 Preadipocytes.

Published in:

2013

By:

Mitterberger, Maria C;
Zwerschke, Werner

Publication type:

Journal Article

Association of Genetic Variances in ADRB1 and PPARGC1a with Two-Kilometre Running Time-Trial Performance in Australian Football League Players: A Preliminary Study.

Published in:

Sports (2075-4663), 2021, v. 9, n. 2, p. 22, doi. 10.3390/sports9020022

By:

Jacob, Ysabel;
Anderton, Ryan S.;
Cochrane Wilkie, Jodie L.;
Rogalski, Brent;
Laws, Simon M.;
Jones, Anthony;
Spiteri, Tania;
Hart, Nicolas H.

Publication type:

Article

Role and Functions of Irisin: A Perspective on Recent Developments and Neurodegenerative Diseases.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 554, doi. 10.3390/antiox14050554

By:

Minuti, Aurelio;
Raffaele, Ivana;
Scuruchi, Michele;
Lui, Maria;
Muscarà, Claudia;
Calabrò, Marco

Publication type:

Article

On the Therapeutic Potential of Heme Oxygenase-1 and Its Metabolites.

Published in:

Antioxidants, 2024, v. 13, n. 10, p. 1243, doi. 10.3390/antiox13101243

By:

Stec, David E.

Publication type:

Article

Hydrogen Sulfide and Irisin, Potential Allies in Ensuring Cardiovascular Health.

Published in:

Antioxidants, 2024, v. 13, n. 5, p. 543, doi. 10.3390/antiox13050543

By:

Flori, Lorenzo;
Benedetti, Giada;
Calderone, Vincenzo;
Testai, Lara

Publication type:

Article

Klotho, Oxidative Stress, and Mitochondrial Damage in Kidney Disease.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 239, doi. 10.3390/antiox12020239

By:

Donate-Correa, Javier;
Martín-Carro, Beatriz;
Cannata-Andía, Jorge B.;
Mora-Fernández, Carmen;
Navarro-González, Juan F.

Publication type:

Article

Change of peroxisome proliferator-activated receptor γ expression pattern in the gerbil dentate gyrus after transient global cerebral ischemia.

Published in:

Anatomy & Cell Biology, 2014, v. 47, n. 2, p. 111, doi. 10.5115/acb.2014.47.2.111

By:

Choong Hyun Lee;
Moo-Ho Won

Publication type:

Article

Hypoglycemic episodes exacerbate skeletal muscle insulin resistance in type 2 diabetes mellitus.

Published in:

Journal of Advanced Pharmaceutical Technology & Research, 2025, v. 16, n. 2, p. 99, doi. 10.4103/JAPTR.JAPTR_388_24

By:

Zufry, Hendra;
Rosdiana, Rosdiana;
Sucipto, Krishna Wardhana;
Ekadamayanti, Agustia Sukri;
Firdausa, Sarah

Publication type:

Article

Application of recombinant peroxisome proliferator-activated receptor-γ coactivator-1α mediates neovascularization in the retina.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1311, doi. 10.3892/mmr.2015.4678

By:

JIAN JIANG;
LIXIN ZHANG;
LU ZHANG;
XIAOBO XIA

Publication type:

Article

Lycium ruthenicum extract alleviates high-fat diet-induced nonalcoholic fatty liver disease via enhancing the AMPK signaling pathway.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 3, p. 3835, doi. 10.3892/mmr.2015.3840

By:

JIAYAO LIN;
YU ZHANG;
XINQING WANG;
WENWEN WANG

Publication type:

Article

Peroxisome proliferator-activated receptor-γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 2, p. 1877, doi. 10.3892/mmr.2015.3641

By:

YONG-ZHI SAN;
YU LIU;
YU ZHANG;
PING-PING SHI;
YU-LAN ZHU

Publication type:

Article

A tandem regression-outlier analysis of a ligand cellular system for key structural modifications around ligand binding.

Published in:

Journal of Cheminformatics, 2013, v. 5, n. 1, p. 1, doi. 10.1186/1758-2946-5-21

By:

Ying-Ting Lin

Publication type:

Article

Circulating PGC-1α and MOTS-c Peptide as Potential Mitochondrial Biomarkers in Patients Undergoing Aortic Valve Replacement.

Published in:

Biologics: Targets & Therapy, 2025, v. 19, p. 87, doi. 10.2147/BTT.S504289

By:

Sánchez-Quintero, María J;
Iboleón, Andrea;
Chaves, Laura Martín;
Vilumbrales, Bárbara Pozo;
Carmona-Segovia, Ada DM;
López, Pilar Martínez;
Romero-Cuevas, Miguel;
Rodríguez-Capitán, Jorge;
Becerra-Muñoz, Víctor M;
Pavón-Morón, Francisco Javier;
Murri, Mora

Publication type:

Article

PGC-1α is associated with Schizothorax prenanti myoblast differentiation.

Published in:

Journal of Applied Animal Research, 2018, v. 46, n. 1, p. 1242, doi. 10.1080/09712119.2018.1490650

By:

Zhao, Yanying;
Li, Ruiwen;
Lin, Yaqiu;
Luo, Fan

Publication type:

Article

Polymorphic Variants Analysis in Peroxisome Proliferator- Activated Receptor Gamma Coactivator 1-Alpha (PPARGC1A) Gene of Indian and Egyptian Buffaloes.

Published in:

Indian Journal of Animal Research, 2023, v. 57, n. 11, p. 1474, doi. 10.18805/IJAR.B-5182

By:

Sihag, Sonia;
Rushdi, Hossam E.;
Kumar, Anil;
Jangra, Alka;
Hassanane, Mohamed S.;
Abdel-Shafy, Hamdy;
Chhokar, Vinod

Publication type:

Article

FBXW7 regulates a mitochondrial transcription program by modulating MITF.

Published in:

Pigment Cell & Melanoma Research, 2018, v. 31, n. 5, p. 636, doi. 10.1111/pcmr.12704

By:

Abbate, Franco;
Badal, Brateil;
Mendelson, Karen;
Aydin, Iraz T.;
Iqbal, Ramiz;
Celebi, Julide T.;
Greenbaum, Benjamin D.;
Solovyov, Alexander;
Serasinghe, Madhavika N.;
Mohammed, Jarvier N.;
Chipuk, Jerry E.

Publication type:

Article

Decision to grow or to invade is at the flick of metabolic switch, PGC1 α.

Published in:

Pigment Cell & Melanoma Research, 2017, v. 30, n. 2, p. 179, doi. 10.1111/pcmr.12558

By:

Hill, Kristen S.;
Kim, Minjung

Publication type:

Article

Effects of Citral on Lipopolysaccharide-Induced Inflammation in Human Umbilical Vein Endothelial Cells.

Published in:

Inflammation, 2016, v. 39, n. 2, p. 663, doi. 10.1007/s10753-015-0292-0

By:

Song, Yan;
Zhao, Hongfeng;
Liu, Jinyang;
Fang, Chao;
Miao, Renying

Publication type:

Article

Naa10p impairs PGC‐1α/Pparγ2 interaction to inhibit mitochondrial protection in pancreatitis.

Published in:

Journal of Cell Communication & Signaling, 2025, v. 19, n. 2, p. 1, doi. 10.1002/ccs3.70015

By:

Du, Jie;
Jiang, Hai;
Zhang, Taizhe;
Zheng, Chuanming;
Ji, Zhong

Publication type:

Article

PGC-1α-Dependent Mitochondrial Adaptation Is Necessary to Sustain IL-2-Induced Activities in Human NK Cells.

Published in:

Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/9605253

By:

Miranda, Dante;
Jara, Claudia;
Ibañez, Jorge;
Ahumada, Viviana;
Acuña-Castillo, Claudio;
Martin, Adrian;
Córdova, Alexandra;
Montoya, Margarita

Publication type:

Article

Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice.

Published in:

Neural Plasticity, 2023, p. 1, doi. 10.1155/2023/9206875

By:

Wei, Wei;
Lin, Zhicheng;
Xu, PeiTao;
Lv, Xinru;
Lin, Libin;
Li, Yongxu;
Zhou, Yangjie;
Lu, Taotao;
Xue, Xiehua

Publication type:

Article

Genetic Deletion of Neuronal PPARγ Enhances the Emotional Response to Acute Stress and Exacerbates Anxiety: An Effect Reversed by Rescue of Amygdala PPARγ Function.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 50, p. 12611, doi. 10.1523/JNEUROSCI.4127-15.2016

By:

Domi, Esi;
Uhrig, Stefanie;
Soverchia, Laura;
Spanagel, Rainer;
Hansson, Anita C.;
Barbier, Estelle;
Heilig, Markus;
Ciccocioppo, Roberto;
Ubaldi, Massimo

Publication type:

Article

PGC-1α Provides a Transcriptional Framework for Synchronous Neurotransmitter Release from Parvalbumin-Positive Interneurons.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 43, p. 14375, doi. 10.1523/JNEUROSCI.1222-14.2014

By:

Lucas, Elizabeth K.;
Dougherty, Sarah E.;
McMeekin, Laura J.;
Reid, Courtney S.;
Dobrunz, Lynn E.;
West, Andrew B.;
Hablitz, John J.;
Cowell, Rita M.

Publication type:

Article

Reduced mitochondrial DNA and OXPHOS protein content in skeletal muscle of children with cerebral palsy.

Published in:

Developmental Medicine & Child Neurology, 2021, v. 63, n. 10, p. 1204, doi. 10.1111/dmcn.14964

By:

von Walden, Ferdinand;
Vechetti, Ivan J;
Englund, Davis;
Figueiredo, Vandré C;
Fernandez‐Gonzalo, Rodrigo;
Murach, Kevin;
Pingel, Jessica;
Mccarthy, John J;
Stål, Per;
Pontén, Eva

Publication type:

Article

Does UCP2 Couple Hyperoxia to Lung Injury?

Published in:

2022

By:

Larson-Casey, Jennifer L.;
Brent Carter, A.

Publication type:

Editorial

Cerebrospinal fluid proteome evaluation in major depressive disorder by mass spectrometry.

Published in:

BMC Psychiatry, 2020, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12888-020-02874-9

By:

Franzen, Avery D.;
Lam, Tukiet T.;
Williams, Kenneth R.;
Nairn, Angus C.;
Duman, Ronald S.;
Sathyanesan, Monica;
Kumar, Vikas;
Carpenter, Linda L.;
Newton, Samuel S.

Publication type:

Article

Regulating glycolysis, the TLR4 signal pathway and expression of RBM3 in mouse liver in response to acute cold exposure.

Published in:

2019

By:

Shi, Hongzhao;
Yao, Ruizhi;
Lian, Shuai;
Liu, Peng;
Liu, Yang;
Yang, Yu Ying;
Yang, Huanmin;
Li, Shize

Publication type:

Report

Genes involved in mitochondrial biogenesis and function may not show synchronised responses to mitochondria in shell gland of laying chickens under infectious bronchitis virus challenge.

Published in:

BMC Molecular & Cell Biology, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12860-019-0190-7

By:

Khan, Samiullah;
Roberts, Juliet;
Wu, Shu-Biao

Publication type:

Article

High glucose and free fatty acids induce endothelial progenitor cell senescence via PGC-1α/SIRT1 signaling pathway.

Published in:

Cell Biology International, 2017, v. 41, n. 10, p. 1146, doi. 10.1002/cbin.10833

By:

Song, Xiaoxiao;
Yang, Boyun;
Qiu, Fuyu;
Jia, Minyue;
Fu, Guosheng

Publication type:

Article

Estrogen-related receptor alpha interacts cooperatively with peroxisome proliferator-activated receptor-gamma coactivator-1alpha to regulate osteocalcin gene expression.

Published in:

Cell Biology International, 2013, v. 37, n. 11, p. 1259, doi. 10.1002/cbin.10148

By:

Wang, Haibin;
Wang, Junjian

Publication type:

Article

CKD-501, a novel selective PPARγ agonist, shows no carcinogenic potential in ICR mice following oral administration for 104 weeks.

Published in:

Journal of Applied Toxicology, 2014, v. 34, n. 12, p. 1271, doi. 10.1002/jat.2918

By:

Moon, Kyoung‐Sik;
Lee, Ji‐Eun;
Lee, Hee Su;
Hwang, In‐Chang;
Kim, Dal‐Hyun;
Park, Hyun‐Kyu;
Choi, Hyun‐Ji;
Jo, Woori;
Son, Woo‐Chan;
Yun, Hyo‐In

Publication type:

Article

Decreased liver peroxisomal β-oxidation accompanied by changes in brain fatty acid composition in aged rats.

Published in:

Neurological Sciences, 2014, v. 35, n. 2, p. 289, doi. 10.1007/s10072-013-1509-3

By:

Yang, Lei;
Zhang, Yu;
Wang, Shasha;
Zhang, Wei;
Shi, Ruling

Publication type:

Article

Correction: Sharma et al. Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors. Biomedicines 2020, 8 , 217.

Published in:

2024

By:

Sharma, Isha;
Deng, Fei;
Kanwar, Yashpal S.

Publication type:

Correction Notice

Alterations in Skeletal Muscle Insulin Signaling DNA Methylation: A Pilot Randomized Controlled Trial of Olanzapine in Healthy Volunteers.

Published in:

Biomedicines, 2024, v. 12, n. 5, p. 1057, doi. 10.3390/biomedicines12051057

By:

Burghardt, Kyle J.;
Burghardt, Paul R.;
Howlett, Bradley H.;
Dass, Sabrina E.;
Zahn, Brent;
Imam, Ahmad A.;
Mallisho, Abdullah;
Msallaty, Zaher;
Seyoum, Berhane;
Yi, Zhengping

Publication type:

Article

Modulation of Renal Injury by Variable Expression of Myo-Inositol Oxygenase (MIOX) via Perturbation in Metabolic Sensors.

Published in:

Biomedicines, 2020, v. 8, n. 7, p. 217, doi. 10.3390/biomedicines8070217

By:

Sharma, Isha;
Deng, Fei;
Kanwar, Yashpal S.

Publication type:

Article

SNP interactions of PGC with its neighbor lncRNAs enhance the susceptibility to gastric cancer/atrophic gastritis and influence the expression of involved molecules.

Published in:

Cancer Medicine, 2018, v. 7, n. 10, p. 5252, doi. 10.1002/cam4.1743

By:

Lv, Zhi;
Sun, Liping;
Xu, Qian;
Gong, Yuehua;
Jing, Jingjing;
Dong, Nannan;
Xing, Chengzhong;
Yuan, Yuan

Publication type:

Article

Past, present and future of research on brain energy metabolism in bipolar disorder.

Published in:

World Psychiatry, 2025, v. 24, n. 1, p. 47, doi. 10.1002/wps.21266

By:

Berk, Michael;
Walder, Ken;
Kim, Jee Hyun

Publication type:

Article

Tomatine Improves Glucose Metabolism and Mitochondrial Respiration in Insulin-Resistant Hepatocyte Cell Lines AML12 and HepG2 via an AMP-Activated Protein Kinase-Dependent Pathway.

Published in:

Cells (2073-4409), 2025, v. 14, n. 5, p. 329, doi. 10.3390/cells14050329

By:

Lee, Yu Geon;
Kim, Donghwan

Publication type:

Article

S-nitrosylated PARIS Leads to the Sequestration of PGC-1α into Insoluble Deposits in Parkinson's Disease Model.

Published in:

Cells (2073-4409), 2022, v. 11, n. 22, p. 3682, doi. 10.3390/cells11223682

By:

Kim, Hanna;
Lee, Ji-Yeong;
Park, Soo Jeong;
Kwag, Eunsang;
Kim, Jihye;
Shin, Joo-Ho

Publication type:

Article