Works about PEROXISOME proliferator-activated receptors

Results: 4673

Differential hepatic activation of mouse and human peroxisome proliferator-activated receptor-α by perfluorohexane sulfonate.

Published in:

Toxicological Sciences, 2025, v. 205, n. 1, p. 47, doi. 10.1093/toxsci/kfaf026

By:

Khan, Yahya;
Schmidt, Annalee M;
Oldro, Kyle J;
Zhu, Xiaoyang;
Kramer, Angelina R;
Hamilton, Sarah R;
Bleil, Katherine O;
Krisko, Ryan M;
Zitzow, Jeremiah D;
Tian, Yuan;
Chang, Shu-Ching;
Walter, Vonn;
Cohen, Samuel M;
Gonzalez, Frank J;
Patterson, Andrew D;
Peters, Jeffrey M

Publication type:

Article

Endocrine-disruptive Potential and Biochemical Effects of Cobalt on Juvenile Catfish (Clarias gariepinus) obtained from Aquaculture Facility in Akure, Ondo State, Nigeria.

Published in:

Journal of Applied Sciences & Environmental Management, 2025, v. 29, n. 4, p. 1107, doi. 10.4314/jasem.v29i4.12

By:

OGUNWOLE, G. A.

Publication type:

Article

Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1554850

By:

Ren, Guilin;
Lin, Yiyou;
Qiu, Jiannan;
Zhang, Congcong;
Chen, Lin;
Zhu, Linwensi;
Fan, Xiaohui;
Dou, Xiaobing;
Liu, Qingsheng

Publication type:

Article

Update on the Management of Cholestatic Pruritus.

Published in:

Gastroenterology & Hepatology, 2025, v. 21, p. 315

By:

Brown, Kimberly

Publication type:

Article

Knockdown of Galectin-3 confers myocardial protection against ischemia-reperfusion injury, modulating oxidative stress, inflammatory response, and the peroxisome proliferator-activated receptor g signaling pathway.

Published in:

CytoJournal, 2025, v. 22, p. 1, doi. 10.25259/Cytojournal_12_2025

By:

Chen, Duo;
Wen, Jingyu;
Zang, Wei;
Lin, Xuehong

Publication type:

Article

Exploration of the protection of mild moxibustion on ovarian function in mice with premature ovarian insufficiency by regulating AMPK/PGC-1a signal, thus inhibiting the response to oxidative stress.

Published in:

Journal of Beijing University of Traditional Chinese Medicine, 2025, v. 48, n. 4, p. 1, doi. 10.3969/j.issn.1006-2157.2025.04.017

By:

Yansu, FANG;
Yaoli, YIN;
Meihong, SHEN;
Jia, LUO

Publication type:

Article

ATF1 and miR-27b-3p drive intervertebral disc degeneration through the PPARG/NF-κB signaling axis.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08186-6

By:

Guo, Wei;
Mu, Kun;
Geng, Jing-Chao;
Xing, Hai-Yang;
Dong, Yu;
Liu, Wen-Dong;
Wang, Shuan-Chi;
Shi, Jia-Xiao;
Xing, Bao-Rui;
Zhao, Jian-Yong;
Li, Xiao-Ming

Publication type:

Article

THE EFFICACY OF CURRENT TREATMENTS FOR NON-ALCOHOLIC FATTY LIVER DISEASE: A SYSTEMATIC REVIEW.

Published in:

Obstetrics & Gynaecology Forum, 2024, v. 34, n. 3, p. 313

By:

Kakade, Satish V.;
P., Patil Dilip;
Laddad, Manisha

Publication type:

Article

Poly- and per-fluoroalkyl substances toxicity on skeletal and cognitive well-being: a comprehensive review.

Published in:

Journal of Environmental Science & Health. Part C. Toxicology & Carcinogenesis, 2025, v. 43, n. 2, p. 159, doi. 10.1080/26896583.2025.2460884

By:

Roy, Vikas C.;
Bala, Rajni;
Mehta, Sakshi

Publication type:

Article

Administration of chiglitazar reverses chronic stress-induced depressive-like symptoms in mice via activation of hippocampal PPARα and BDNF.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1587399

By:

Zhou, Jiu-Jian;
Zhao, Jie;
Gao, Shang-Yan;
Gao, Yuan-yuan;
Chen, Cheng;
Ding, Yi;
Wu, Zhong-hua;
Chen, Pu-Jian

Publication type:

Article

Diabetes and calcific aortic valve disease: implications of glucose-lowering medication as potential therapy.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1583267

By:

Liu, Feng;
Cai, Haipeng

Publication type:

Article

Cassiae semen extract ameliorates hyperlipidemia in rats by modulating lipid metabolism and FcγR-mediated immune regulation.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1546119

By:

Lv, Mingyue;
Zheng, Yannan;
Yuan, Man;
Zhang, Errui;
Zheng, Min;
Liu, Guangyao;
Gu, Weiliang;
Xu, Hongxi

Publication type:

Article

Fatty acid metabolism suppresses neonatal cardiomyocyte proliferation by increasing PDK4 and HMGCS2 expression through PPARδ.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0318178

By:

Tanaka, Shota;
Hirota, Akane;
Okada, Yoshiaki;
Obana, Masanori;
Fujio, Yasushi

Publication type:

Article

Antitumor Effects of Troglitazone and Its Association with Peroxisome Proliferator-Activated Receptor Gamma Activation in FaDu Human Hypopharyngeal Carcinoma Cells.

Published in:

Indian Journal of Pharmaceutical Sciences, 2025, v. 87, n. 2, p. 59

By:

THU DO;
LOAN, T. T.;
LE, T. D.;
VU, P. D.;
HOON YOO

Publication type:

Article

下丘脑室旁核CBS 通过影响PGC-1a降低自发性高血压大鼠的血压.

Published in:

Journal of Xi'an Jiaotong University (Medical Sciences), 2025, v. 46, n. 2, p. 227, doi. 10.7652/jdyxb202502006

By:

于晓静;
高雅楠;
李迎;
涂丽梅;
高千喜;
孙要军;
和荣丽;
康玉明;
史小莲

Publication type:

Article

LIBX‐A401: A Novel Selective Inhibitor of Acyl‐CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode.

Published in:

Angewandte Chemie, 2025, v. 137, n. 19, p. 1, doi. 10.1002/ange.202500518

By:

Mazhari Dorooee, Darius;
Ravez, Séverine;
Vertommen, Didier;
Renault, Nicolas;
Papadopoulos, Nicolas;
Marteau, Romain;
Charnelle, Emeline;
Porte, Karine;
Gobert, Alexandre;
Hennuyer, Nathalie;
Herinckx, Gaetan;
Pautric, Maëla;
Jonneaux, Aurélie;
Devedjian, Jean Christophe;
Devos, David;
Staels, Bart;
Melnyk, Patricia;
Constantinescu, Stefan N.;
Frédérick, Raphaël;
El Bakali, Jamal

Publication type:

Article

The anti-diabetic PPARγ agonist Pioglitazone inhibits cell proliferation and induces metabolic reprogramming in prostate cancer.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02320-y

By:

Atas, Emine;
Berchtold, Kerstin;
Schlederer, Michaela;
Prodinger, Sophie;
Sternberg, Felix;
Pucci, Perla;
Steel, Christopher;
Matthews, Jamie D.;
James, Emily R.;
Philippe, Cécile;
Trachtová, Karolína;
Moazzami, Ali A.;
Artamonova, Nastasiia;
Melchior, Felix;
Redmer, Torben;
Timelthaler, Gerald;
Pohl, Elena E.;
Turner, Suzanne D.;
Heidegger, Isabel;
Krueger, Marcus

Publication type:

Article

Mechanistic Insights into N-Oleoylethanolamide-Mediated Hepatoprotection via PPAR-α.

Published in:

Biocell, 2025, v. 49, n. 4, p. 607, doi. 10.32604/biocell.2025.061606

By:

Ivashkevich, Darya;
Ponomarenko, Arina;
Manzhulo, Igor;
Dyuizen, Inessa

Publication type:

Article

PPAR-γ agonist pioglitazone and the risks of malignancy among type2 diabetes mellitus patients.

Published in:

Acta Diabetologica, 2025, v. 62, n. 4, p. 531, doi. 10.1007/s00592-024-02378-y

By:

See, Lai-Chu;
Wu, Chao-Yi;
Tsai, Chung-Ying;
Lee, Cheng-Chia;
Chen, Jia-Jin;
Jenq, Chang-Chyi;
Chen, Chao-Yu;
Chen, Yung-Chang;
Yen, Chieh-Li;
Yang, Huang-Yu

Publication type:

Article

Effect of chromium citrate on the mechanism of glucose transport and insulin resistance in Buffalo rat liver cells.

Published in:

Indian Journal of Pharmacology, 2020, v. 52, n. 1, p. 31, doi. 10.4103/ijp.IJP_608_18

By:

Zhang, Weijie;
Chen, Hui;
Ding, Yangyang;
Xiang, Qingfang;
Zhao, Jie;
Feng, Weiwei;
Yang, Liuqing

Publication type:

Article

Anti-inflammatory and anti-hyperalgesic effect of all-trans retinoic acid in carrageenan-induced paw edema in Wistar rats: Involvement of peroxisome proliferator-activated receptor-β/δ receptors.

Published in:

Indian Journal of Pharmacology, 2013, v. 45, n. 3, p. 278, doi. 10.4103/0253-7613.111944

By:

Gill, Navneet;
Bijjem, Krishna Reddy V.;
Sharma, Pyare L.

Publication type:

Article

Telmisartan use and risk of dementia in type 2 diabetes patients with hypertension: A population-based cohort study.

Published in:

2021

By:

Liu, Chi-Hung;
Sung, Pi-Shan;
Li, Yan-Rong;
Huang, Wen-Kuan;
Lee, Tay-Wey;
Huang, Chin-Chang;
Lee, Tsong-Hai;
Chen, Tien-Hsing;
Wei, Yi-Chia

Publication type:

journal article

Computational design and experimental confirmation of conformationally constrained peptides to compete with coactivators for pediatric PPARα by minimizing indirect readout effect.

Published in:

Journal of Bioinformatics & Computational Biology, 2022, v. 20, n. 5, p. 1, doi. 10.1142/S0219720022500202

By:

Gao, Caijie;
Zhao, Xu;
Fan, Jianrong

Publication type:

Article

Identification of Potential Drug Targets of Calix[4]arene by Reverse Docking.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 42, p. 1, doi. 10.1002/chem.202400871

By:

Giugliano, Giulia;
Gajo, Margherita;
Marforio, Tainah Dorina;
Zerbetto, Francesco;
Mattioli, Edoardo Jun;
Calvaresi, Matteo

Publication type:

Article

Impact of pemafibrate on lipid profile and insulin resistance in hypertriglyceridemic patients with coronary artery disease and metabolic syndrome.

Published in:

Heart & Vessels, 2024, v. 39, n. 6, p. 486, doi. 10.1007/s00380-024-02363-z

By:

Nakamura, Akihiro;
Kagaya, Yuta;
Saito, Hiroki;
Kanazawa, Masanori;
Sato, Kenjiro;
Miura, Masanobu;
Kondo, Masateru;
Endo, Hideaki

Publication type:

Article

The satiety factor oleoylethanolamide impacts hepatic lipid and glucose metabolism in goldfish.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2016, v. 186, n. 8, p. 1009, doi. 10.1007/s00360-016-1009-x

By:

Gómez-Boronat, Miguel;
Isorna, Esther;
Pedro, Nuria;
Delgado, María;
Velasco, Cristina;
Soengas, José

Publication type:

Article

Abrogation of postprandial triglyceridemia with dual PPAR α/γ agonist in type 2 diabetes mellitus: a randomized, placebo-controlled study.

Published in:

Acta Diabetologica, 2020, v. 57, n. 7, p. 809, doi. 10.1007/s00592-020-01487-8

By:

Rastogi, Ashu;
Dunbar, Richard L.;
Thacker, Hemant P.;
Bhatt, Jayesh;
Parmar, Krupi;
Parmar, Deven V.

Publication type:

Article

Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic.

Published in:

Acta Diabetologica, 2020, v. 57, n. 6, p. 759, doi. 10.1007/s00592-020-01522-8

By:

Luzi, Livio;
Radaelli, Maria Grazia

Publication type:

Article

The novel loss of function Ile354Val mutation in PPARG causes familial partial lipodystrophy.

Published in:

Acta Diabetologica, 2020, v. 57, n. 5, p. 589, doi. 10.1007/s00592-019-01462-y

By:

Padova, Giuseppa;
Prudente, Sabrina;
Vinciguerra, Federica;
Sudano, Dora;
Baratta, Roberto;
Bellacchio, Emanuele;
Trischitta, Vincenzo;
Vallone, Antonino;
Sciacca, Laura;
Frittitta, Lucia

Publication type:

Article

Co-expression of fat1 and fat2 in transgenic pigs promotes synthesis of polyunsaturated fatty acids.

Published in:

Transgenic Research, 2019, v. 28, n. 3/4, p. 369, doi. 10.1007/s11248-019-00127-4

By:

Tang, Fei;
Yang, Xiaofeng;
Liu, Dewu;
Zhang, Xianwei;
Huang, Xiaoling;
He, Xiaoyan;
Shi, Junsong;
Li, Zicong;
Wu, Zhenfang

Publication type:

Article

Angiopoietin-Like Protein 4 Is Involved in Manganese Superoxide Dismutase-Mediated Suppression of Breast Cancer Cell Growth.

Published in:

Bulletin of Experimental Biology & Medicine, 2022, v. 173, n. 2, p. 240, doi. 10.1007/s10517-022-05526-y

By:

Li, P.;
Zeng, X.;
Liu, Y.;
Lin, M.

Publication type:

Article

Umbelliferone ameliorates oxidative stress and testicular injury, improves steroidogenesis and upregulates peroxisome proliferator-activated receptor gamma in type 2 diabetic rats.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 4, p. 573, doi. 10.1093/jpp/rgab083

By:

Allam, Mohamed A M;
Khowailed, Akef A;
Elattar, Samah;
Mahmoud, Ayman M

Publication type:

Article

Sildenafil improves right ventricular remodelling in monocrotaline-induced rats by decreasing myocardial apoptosis and activating peroxisome proliferator-activated receptors.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 2, p. 145, doi. 10.1093/jpp/rgaa017

By:

Ye-li Li;
Yi-qi Li;
Fan-qun Zeng;
Xiao-ying Lin;
Xiao-tong Li;
Xing-qiao Ren;
Dan-li Yang

Publication type:

Article

Pinoresinol‐4‐O‐β‐D‐glucopyranoside: a lignan from prunes (Prunus domestica) attenuates oxidative stress, hyperglycaemia and hepatic toxicity in vitro and in vivo.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 12, p. 1830, doi. 10.1111/jphp.13358

By:

Youssef, Fadia S.;
Ashour, Mohamed L.;
El‐Beshbishy, Hesham A.;
Ahmed Hamza, Alaaeldin;
Singab, Abdel Nasser B.;
Wink, Michael

Publication type:

Article

HWL‐088, a new and highly effective FFA1/PPARδ dual agonist, attenuates nonalcoholic steatohepatitis by regulating lipid metabolism, inflammation and fibrosis.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 11, p. 1564, doi. 10.1111/jphp.13342

By:

Hu, Lijun;
Zhou, Zongtao;
Deng, Liming;
Ren, Qiang;
Cai, Zongyu;
Wang, Bin;
Li, Zheng;
Wang, Guangji

Publication type:

Article

Effect of GSK‐137647A, the first non‐carboxylic FFA4 agonist, on the osteogenic and adipogenic differentiation of bone mesenchymal stem cells in db/db mice.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 3, p. 461, doi. 10.1111/jphp.13217

By:

Wang, Chunlei;
Liu, Yanmei;
Pan, Yuan;
Jin, Hui

Publication type:

Article

TNBG‐5602, a novel derivative of quinoxaline, inhibits liver cancer growth via upregulating peroxisome proliferator‐activated receptor γ in vitro and in vivo.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 11, p. 1684, doi. 10.1111/jphp.13159

By:

Hu, Xuelian;
Wan, Chunmei;
Gan, Zongjie;
Liu, Rongxing;
Chen, Yongjie;
Wang, Jing;
Gan, Linling;
Chen, Yuhang;
Li, Yingbo;
He, Baicheng;
Yu, Yu

Publication type:

Article

PPARα‐independent action against metabolic syndrome development by fibrates is mediated by inhibition of STAT3 signalling.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 12, p. 1630, doi. 10.1111/jphp.13014

By:

Hua, Huiying;
Yang, Julin;
Lin, Hante;
Xi, Yang;
Dai, Manyun;
Xu, Gangming;
Wang, Fuyan;
Liu, Lihong;
Zhao, Tingqi;
Huang, Jing;
Gonzalez, Frank J.;
Liu, Aiming

Publication type:

Article

In-vivo antioxidant and anti-inflammatory activity of rosiglitazone, a peroxisome proliferator-activated receptor-gamma ( PPAR-γ) agonists in animal model of bronchial asthma.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 10, p. 1421, doi. 10.1111/jphp.12445

By:

El‐Naa, Mona M.;
El‐Refaei, Mohamed F.;
Nasif, Wesam A.;
Abduljawad, Suha H.;
El‐Brairy, Amany I.;
El‐Readi, Mahmoud Z.

Publication type:

Article

Establishment of a cell-based drug screening model for identifying agonists of human peroxisome proliferator-activated receptor gamma (PPAR γ).

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 5, p. 719, doi. 10.1111/j.2042-7158.2012.01462.x

By:

Ma, Jing-Jing;
Zhang, Tao;
Fang, Ning;
Zou, Yan;
Gong, Qi-Hai;
Yu, Li-Mei;
Chen, Dai-Xiong

Publication type:

Article

Poloxamer 407 as a general lipase inhibitor: its implications in lipid metabolism and atheroma formation in C57BL/6 mice.

Published in:

Journal of Pharmacy & Pharmacology, 2010, v. 62, n. 12, p. 1807, doi. 10.1111/j.2042-7158.2010.01138.x

By:

Johnston, Thomas P.

Publication type:

Article

Evidence of the involvement of K<sup>+</sup> channels and PPAR γ receptors in the antidepressant-like activity of diphenyl diselenide in mice.

Published in:

Journal of Pharmacy & Pharmacology, 2010, v. 62, n. 9, p. 1121, doi. 10.1111/j.2042-7158.2010.01132.x

By:

Wilhelm, Ethel A.;
Jesse, Cristiano R.;
Bortolatto, Cristiani F.;
Barbosa, Nilda B.V.;
Nogueira, Cristina W.

Publication type:

Article

Comparative study between the effect of the peroxisome proliferator activated receptor-α ligands fenofibrate and n-3 polyunsaturated fatty acids on activation of 5′-AMP-activated protein kinase-α1 in high-fat fed rats.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 10, p. 1339, doi. 10.1211/jpp.61.10.0010

By:

Tarek M. Kamal Motawi;
Reem M. Hashem;
Laila A. Rashed;
Sabry M. Abd El-Razek

Publication type:

Article

Aleglitazar treats non-alcoholic steatohepatitis in mice through PPAR dependent pathway.

Published in:

Zagazig University Medical Journal, 2023, v. 29, n. 5, p. 1402, doi. 10.21608/ZUMJ.2022.152115.2606

By:

Nageeb, Mahitab M.

Publication type:

Article

Omentin-1 antagonizes High Fat Induced Bone Loss in Rats and Promotes Bone Growth via AMPK/mTORC1/PPAR-γ and GDF-11 Signaling Pathway.

Published in:

Zagazig University Medical Journal, 2023, v. 29, n. 4, p. 1124, doi. 10.21608/zumj.2023.205450.2788

By:

El-Malkey, Nanees F.;
Elwany, Nisreen E.;
Goda, Nehal I. A.;
Aref, Mohamed;
Khalil, Sama S.

Publication type:

Article

Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder.

Published in:

BMC Molecular & Cell Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12860-023-00497-y

By:

Sato, Fuyuki;
Bhawal, Ujjal K.;
Oikawa, Kosuke;
Muragaki, Yasuteru

Publication type:

Article

USP22 enhances atherosclerotic plaque stability and macrophage efferocytosis by stabilizing PPARγ.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08116-6

By:

Tang, Senhu;
Lu, Chuanghong;
Meng, Zhongyuan;
Ye, Zihua;
Qin, Yue;
Na, Na;
Xian, Shenglin;
Huang, Feng;
Zeng, Zhiyu

Publication type:

Article

Coordinated transcriptional upregulation of oxidative metabolism proteins in long-lived endocrine mutant mice.

Published in:

GeroScience, 2023, v. 45, n. 5, p. 2967, doi. 10.1007/s11357-023-00849-8

By:

Elmansi, Ahmed M.;
Miller, Richard A.

Publication type:

Article

低鱼粉饮食中添加半胱氨酸对卵形鲳鲹幼鱼脂质和蛋白质代谢的影响.

Published in:

South China Fisheries Science, 2023, v. 19, n. 4, p. 116, doi. 10.12131/20230030

By:

刘佳兴;
郭华阳;
朱克诚;
刘宝锁;
张楠;
冼霖;
张殿昌

Publication type:

Article

The Role of Natriuretic Peptides in the Regulation of Cardiac Tolerance to Ischemia/Reperfusion and Postinfarction Heart Remodeling.

Published in:

Journal of Cardiovascular Pharmacology & Therapeutics, 2021, v. 26, n. 2, p. 131, doi. 10.1177/1074248420952243

By:

Krylatov, Andrey V.;
Tsibulnikov, Sergey Y.;
Mukhomedzyanov, Alexander V.;
Boshchenko, Alla A.;
Goldberg, Victor E.;
Jaggi, Amteshwar S.;
Erben, Reinhold G.;
Maslov, Leonid N.

Publication type:

Article