Works matching DE "PERAMPANEL"

Results: 142

Severe perampanel intoxication presenting with rapidly progressive dementia.

Published in:

2025

By:

Wada, Takahide;
Saitoh, Yuji;
Asano, Yuri;
Honda, Masayuki;
Takahashi, Kazushi

Publication type:

Letter

Systematic review of pharmacological treatment options for orthostatic tremor in prospective patient cohorts and randomized controlled trials.

Published in:

Neurological Sciences, 2025, v. 46, n. 8, p. 3419, doi. 10.1007/s10072-025-08129-3

By:

Sauthoff, Lena;
Achutegui, Maider Iza;
Ye, Lan;
Niesmann, Clara;
Wegner, Florian;
Höllerhage, Matthias;
Klietz, Martin

Publication type:

Article

Cost-effectiveness of therapeutic drug monitoring of perampanel for pediatrics with epilepsy: real-world data.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1549069

By:

Hu, Yani;
Miao, Pu;
Chen, Shunan;
Mao, Fengqian;
Wang, Suhong;
Feng, Jianhua;
Chen, Jie;
Yu, Lingyan;
Dai, Haibin

Publication type:

Article

Precision dosing of perampanel in pediatric patients receiving oxcarbazepine combination therapy: physiologically based pharmacokinetic modeling and simulation.

Published in:

Expert Review of Clinical Pharmacology, 2025, v. 18, n. 6, p. 425, doi. 10.1080/17512433.2025.2527079

By:

Liu, Si-Ting;
Ke, Cheng-Jie;
Su, Jing;
Qian, Yu-Die;
Wu, Wan-Hong;
Lin, Xi;
Lin, Wei-Wei

Publication type:

Article

P.085 Exploring the efficacy and safety of perampanel in epilepsia partialis continua: a case series.

Published in:

2025

By:

Lahsaee, S;
Whatley, B

Publication type:

Abstract

What drives hyperammonemic encephalopathy in AED users: monotherapy risks or polypharmacy perils?

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1477127

By:

Shan, Qing;
Wang, Lei;
Liu, Xia;
Chen, Yan;
Li, Bing;
Guo, Yuhang;
Fu, Qiang;
Guo, Jinmin

Publication type:

Article

Real-world utilization of Cenobamate as adjunct therapy in office-based neurology: practical tips and insights for titration.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1558614

By:

House, Patrick M.;
Wiese, Lars

Publication type:

Article

The Cognitive and Behavioural Effects of Perampanel in Children with Neurodevelopmental Disorders: A Systematic Review.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 2, p. 372, doi. 10.3390/jcm13020372

By:

Scorrano, Giovanna;
Lattanzi, Simona;
Salpietro, Vincenzo;
Giannini, Cosimo;
Chiarelli, Francesco;
Matricardi, Sara

Publication type:

Article

Replacement of Valproic Acid with New Anti-Seizure Medications in Idiopathic Generalized Epilepsy.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 15, p. 4582, doi. 10.3390/jcm11154582

By:

Fujimoto, Ayataka;
Enoki, Hideo;
Hatano, Keisuke;
Sato, Keishiro;
Okanishi, Tohru

Publication type:

Article

Intravenous Perampanel as an Interchangeable Alternative to Oral Perampanel: A Randomized, Crossover, Phase I Pharmacokinetic and Safety Study.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 7, p. 878, doi. 10.1002/cpdd.1107

By:

Hussein, Ziad;
Majid, Oneeb;
Boyd, Peter;
Aluri, Jagadeesh;
Ngo, Leock Y;
Reyderman, Larisa

Publication type:

Article

Psychiatric and Behavioural Side Effects Associated With Perampanel in Patients With Temporal Lobe Epilepsy. A Real-World Experience.

Published in:

Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.839985

By:

Mammì, Anna;
Ferlazzo, Edoardo;
Gasparini, Sara;
Bova, Valentina;
Neri, Sabrina;
Labate, Angelo;
Mastroianni, Giovanni;
Bianco, Concetta Lo;
Cianci, Vittoria;
Aguglia, Umberto

Publication type:

Article

Perampanel, an AMPAR antagonist, alleviates experimental intracerebral hemorrhage-induced brain injury via necroptosis and neuroinflammation.

Published in:

Molecular Medicine Reports, 2021, v. 24, n. 2, p. N.PAG, doi. 10.3892/mmr.2021.12183

By:

Yang, Lixiang;
Wang, Yue;
Zhang, Can;
Chen, Tao;
Cheng, Huilin

Publication type:

Article

Successful case of Lance-Adams syndrome treatment with early use of perampanel after targeted therapeutic hypothermia.

Published in:

Neurology Asia, 2023, v. 28, n. 2, p. 445, doi. 10.54029/2023uax

By:

Ji Ho Lee;
Dong Hun Lee

Publication type:

Article

An overview of liquid chromatographic methods for analyzing new generation anti-epileptic drugs.

Published in:

2022

By:

ALSaeedy, Mohammed;
Hasan, Ahmed;
Al-Adhreai, Arwa;
Alrabie, Ali;
Qaba, Hafsah;
Mashrah, Abdulrahman;
Öncü-Kaya, Elif Mine

Publication type:

Literature Review

Clinical effects and outcomes of perampanel overdoses reported to U.S. poison centers.

Published in:

Clinical Toxicology (15563650), 2022, v. 60, n. 2, p. 239, doi. 10.1080/15563650.2021.1945083

By:

Minhaj, Faisal Syed;
Leonard, James B.;
Klein-Schwartz, Wendy

Publication type:

Article

Long‐term safety and efficacy of adjunctive perampanel in pediatric patients (ages 4 to <12 years) with inadequately controlled focal‐onset seizures or generalized tonic–clonic seizures.

Published in:

Epilepsia (Series 4), 2025, v. 66, n. 4, p. 1097, doi. 10.1111/epi.18242

By:

Flamini, Robert;
Fogarasi, Andras;
Omatsu, Hirowo;
Milh, Mathieu;
Phillips, Steven;
Patten, Anna;
Takase, Takao;
Ngo, Leock Y.

Publication type:

Article

Efficacy and safety of perampanel in patients with seizures associated with Lennox–Gastaut syndrome: A randomized trial.

Published in:

Epilepsia (Series 4), 2025, v. 66, n. 2, p. 379, doi. 10.1111/epi.18193

By:

Vossler, David G.;
Porter, Brenda E.;
Kira, Ryutaro;
Lee, Jeehun;
Aeby, Alec;
Patten, Anna;
Cheng, Jocelyn Y.;
Ngo, Leock Y.

Publication type:

Article

Time to prerandomization seizure count design sufficiently assessed the safety and tolerability of perampanel for the treatment of primary generalized tonic–clonic seizures.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 8, p. 2412, doi. 10.1111/epi.18023

By:

Kerr, Wesley T.;
Ngo, Leock Y.;
Zhu, Liang;
Patten, Anna;
Cheng, Jocelyn Y.;
Reddy, Advith S.;
French, Jacqueline A.

Publication type:

Article

Population pharmacokinetics and dosing optimization of perampanel in children with epilepsy: A real‐world study.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 6, p. 1687, doi. 10.1111/epi.17954

By:

Li, Sichan;
Yi, Jiaqin;
Tuo, YaLi;
Nie, Gang;
Wang, Jun;
Wang, Yang;
Sun, Dan;
Liu, Zhisheng

Publication type:

Article

Value of drug level concentrations of brivaracetam, lacosamide, and perampanel in care of people with epilepsy.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 3, p. 620, doi. 10.1111/epi.17873

By:

Hentschel, Matthias;
Stoffel‐Wagner, Birgit;
Surges, Rainer;
von Wrede, Randi;
Dolscheid‐Pommerich, Ramona Christina

Publication type:

Article

Correction to "Perampanel as precision therapy in rare genetic epilepsies".

Published in:: 2024
Publication type:: Correction Notice

Perampanel for the treatment of people with idiopathic generalized epilepsy in clinical practice.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 8, p. 2094, doi. 10.1111/epi.17631

By:

Trinka, Eugen;
Alsaadi, Taoufik;
Goji, Hiroko;
Maehara, Taketoshi;
Takahashi, Satoru;
Jacobs, Julia;
Renna, Rosaria;
Gil‐López, Francisco José;
McMurray, Rob;
Sáinz‐Fuertes, Ricardo;
Villanueva, Vicente

Publication type:

Article

Current treatment options for familial adult myoclonus epilepsy.

Published in:

Epilepsia (Series 4), 2023, v. 64, p. S58, doi. 10.1111/epi.17590

By:

Coppola, Antonietta;
Dubbioso, Raffaele;
Cuccurullo, Claudia;
Licchetta, Laura;
Carreno, Mar;
Hirsch, Edouard;
Bilo, Leonilda

Publication type:

Article

Long‐term effectiveness of add‐on perampanel in patients with Lennox–Gastaut syndrome: A multicenter retrospective study.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 6, p. e98, doi. 10.1111/epi.17601

By:

Matricardi, Sara;
Cesaroni, Elisabetta;
Bonanni, Paolo;
Foschi, Nicoletta;
D′Aniello, Alfredo;
Di Gennaro, Giancarlo;
Striano, Pasquale;
Cappanera, Silvia;
Siliquini, Sabrina;
Freri, Elena;
Ragona, Francesca;
Granata, Tiziana;
Deleo, Francesco;
Villani, Flavio;
Russo, Angelo;
Messana, Tullio;
Siri, Laura;
Bagnasco, Irene;
Vignoli, Aglaia;
Operto, Francesca Felicia

Publication type:

Article

Perampanel as precision therapy in rare genetic epilepsies.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 4, p. 866, doi. 10.1111/epi.17530

By:

Nissenkorn, Andreea;
Kluger, Gerhard;
Schubert‐Bast, Susanne;
Bayat, Allan;
Bobylova, Marya;
Bonanni, Paolo;
Ceulemans, Berten;
Coppola, Antonietta;
Di Bonaventura, Carlo;
Feucht, Martha;
Fuchs, Anne;
Gröppel, Gudrun;
Heimer, Gali;
Herdt, Brigitte;
Kulikova, Sviatlana;
Mukhin, Konstantin;
Nicassio, Stefania;
Orsini, Alessandro;
Panagiotou, Maria;
Pringsheim, Milka

Publication type:

Article

Cost‐effectiveness of cenobamate for focal seizures in people with drug‐resistant epilepsy.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 4, p. 843, doi. 10.1111/epi.17506

By:

Laskier, Vicki;
Agyei‐Kyeremateng, Kenneth K.;
Eddy, Alex E.;
Patel, Dilip;
Mulheron, Stuart;
James, Samuel;
Thomas, Rhys H.;
Sander, Josemir W.

Publication type:

Article

Verbal fluency functional magnetic resonance imaging detects anti‐seizure effects and affective side effects of perampanel in people with focal epilepsy.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 2, p. e9, doi. 10.1111/epi.17493

By:

Xiao, Fenglai;
Caciagli, Lorenzo;
Wandschneider, Britta;
Fleury, Marine;
Binding, Lawrence;
Giampiccolo, Davide;
Hill, Andrea;
Galovic, Marian;
Foong, Jaqueline;
Zhou, Dong;
Sander, Josemir W.;
Duncan, John S.;
Koepp, Matthias J.

Publication type:

Article

A gain‐of‐function GRIA2 variant associated with neurodevelopmental delay and seizures: Functional characterization and targeted treatment.

Published in:

Epilepsia (Series 4), 2022, v. 63, n. 12, p. e156, doi. 10.1111/epi.17419

By:

Coombs, Ian D.;
Ziobro, Julie;
Krotov, Volodymyr;
Surtees, Taryn‐Leigh;
Cull‐Candy, Stuart G.;
Farrant, Mark

Publication type:

Article

Time to exceed pre‐randomization monthly seizure count for perampanel in participants with primary generalized tonic–clonic seizures: A potential clinical end point.

Published in:

Epilepsia (Series 4), 2022, v. 63, n. 11, p. 2994, doi. 10.1111/epi.17411

By:

Kerr, Wesley T.;
Brandt, Christian;
Ngo, Leock Y.;
Patten, Anna;
Cheng, Jocelyn Y.;
Kramer, Lynn;
French, Jacqueline A.

Publication type:

Article

Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam.

Published in:

Archives of Toxicology, 2021, v. 95, n. 7, p. 2459, doi. 10.1007/s00204-021-03053-9

By:

Zolkowska, Dorota;
Dhir, Ashish;
Rogawski, Michael A.

Publication type:

Article

Prophylactic Administration of Perampanel for Post-Stroke Epilepsy (PROPELLER Study): A Trial Protocol.

Published in:

Methods & Protocols, 2024, v. 7, n. 5, p. 79, doi. 10.3390/mps7050079

By:

Yamada, Shuichi;
Nakagawa, Ichiro;
Kotsugi, Masashi;
Asada, Kiyoshi;
Kasahara, Masato

Publication type:

Article

Perampanel in chronic insomnia. A case control study of 33 patients.

Published in:

European Psychiatry, 2020, v. 63, p. S260

By:

Gisbert, E. Suarez;
Abenza Abildúa, M. J.

Publication type:

Article

Effectiveness and safety of Perampanel in refractory status epilepticus: a case series.

Published in:

Neurological Sciences, 2025, v. 46, n. 2, p. 879, doi. 10.1007/s10072-024-07798-w

By:

Renna, Rosaria;
Andreone, Vincenzo;
Barone, Paolo;
Penza, Pietro

Publication type:

Article

Perampanel as a novel treatment for subcortical myoclonus in myoclonus-dystonia syndrome.

Published in:

Neurological Sciences, 2023, v. 44, n. 8, p. 2943, doi. 10.1007/s10072-023-06803-y

By:

Belli, Elisabetta;
Del Prete, Eleonora;
Unti, Elisa;
Mazzucchi, Sonia;
Palermo, Giovanni;
Ceravolo, Roberto

Publication type:

Article

Efficacy and tolerability of perampanel in a patient with Late-Onset myoclonic epilepsy in Down syndrome (LOMEDS): a case report.

Published in:

Neurological Sciences, 2023, v. 44, n. 2, p. 757, doi. 10.1007/s10072-022-06452-7

By:

Corniello, Clarissa;
Dono, Fedele;
Evangelista, Giacomo;
Consoli, Stefano;
Sensi, Stefano L.

Publication type:

Article

Perampanel as first add-on choice on the treatment of mesial temporal lobe epilepsy: an observational real-life study.

Published in:

Neurological Sciences, 2021, v. 42, n. 4, p. 1389, doi. 10.1007/s10072-020-04636-7

By:

Labate, Angelo;
Fortunato, Francesco;
Giugno, Alessia;
Martino, Iolanda;
Caligiuri, Maria Eugenia;
Gambardella, Antonio

Publication type:

Article

Efficacy and Tolerability of Perampanel in Brain Tumor-Related Epilepsy: A Systematic Review.

Published in:

Biomedicines, 2023, v. 11, n. 3, p. 651, doi. 10.3390/biomedicines11030651

By:

Rossi, Jessica;
Cavallieri, Francesco;
Bassi, Maria Chiara;
Biagini, Giuseppe;
Rizzi, Romana;
Russo, Marco;
Bondavalli, Massimo;
Iaccarino, Corrado;
Pavesi, Giacomo;
Cozzi, Salvatore;
Giaccherini, Lucia;
Najafi, Masoumeh;
Pisanello, Anna;
Valzania, Franco

Publication type:

Article

Repurposed Edaravone, Metformin, and Perampanel as a Potential Treatment for Hypoxia–Ischemia Encephalopathy: An In Vitro Study.

Published in:

Biomedicines, 2022, v. 10, n. 12, p. 3043, doi. 10.3390/biomedicines10123043

By:

Silva, Daniela;
Rocha, Ruben;
Correia, Ana Salomé;
Mota, Bárbara;
Madeira, Maria Dulce;
Vale, Nuno;
Cardoso, Armando

Publication type:

Article

The Antiepileptic Drug Oxcarbazepine Inhibits the Growth of Patient-Derived Isocitrate Dehydrogenase Mutant Glioma Stem-like Cells.

Published in:

Cells (2073-4409), 2023, v. 12, n. 8, p. 1200, doi. 10.3390/cells12081200

By:

Dao Trong, Philip;
Jungwirth, Gerhard;
Unterberg, Andreas;
Herold-Mende, Christel;
Warta, Rolf

Publication type:

Article

A pharmacovigilance approach for assessing the occurrence of suicide-related events induced by antiepileptic drugs using the Japanese adverse drug event report database.

Published in:

Frontiers in Psychiatry, 2023, v. 13, p. 1, doi. 10.3389/fpsyt.2022.1091386

By:

Takenao Koseki;
Mikako Horie;
Satomi Kumazawa;
Tetsuo Nakabayashi;
Shigeki Yamada

Publication type:

Article

Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory Epilepsy.

Published in:

Pharmaceutics, 2023, v. 15, n. 6, p. 1704, doi. 10.3390/pharmaceutics15061704

By:

Silva, Rui;
Colom, Helena;
Bicker, Joana;
Almeida, Anabela;
Silva, Ana;
Sales, Francisco;
Santana, Isabel;
Falcão, Amílcar;
Fortuna, Ana

Publication type:

Article

Efficacy of Perampanel in Refractory and Super-Refractory Status Epilepticus with Suspected Inflammatory Etiology: A Case Series.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 1, p. 28, doi. 10.3390/ph17010028

By:

Nilo, Annacarmen;
Vogrig, Alberto;
Belluzzo, Marco;
Lettieri, Christian;
Verriello, Lorenzo;
Valente, Mariarosaria;
Pauletto, Giada

Publication type:

Article

Frontal Hypoperfusion and the Effectiveness of Perampanel in Long-Lived Patient with Lafora Disease.

Published in:

Case Reports in Neurology, 2021, v. 13, n. 1, p. 211, doi. 10.1159/000514243

By:

Obara, Koji;
Abe, Erika;
Toyoshima, Itaru

Publication type:

Article

The Effectiveness of Perampanel for Myoclonic Seizures in Down Syndrome with Isodicentric Chromosome 21.

Published in:

Case Reports in Neurology, 2020, v. 12, n. 3, p. 270, doi. 10.1159/000508357

By:

Obara, Koji;
Imota, Tsuyoshi;
Mamiya, Shigeo;
Toyoshima, Itaru

Publication type:

Article

Evaluation and improvement of CuI‐mediated <sup>11</sup>C‐cyanation.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2023, v. 66, n. 3, p. 95, doi. 10.1002/jlcr.4016

By:

Ishii, Hideki;
Yamasaki, Tomoteru;
Okamura, Toshimitsu;
Zhang, Yiding;
Kurihara, Yusuke;
Ogawa, Masanao;
Nengaki, Nobuki;
Zhang, Ming‐Rong

Publication type:

Article

Investigating the Relationship Between Anti-seizure Medications and Bleeding Disorders: A Comprehensive Review of the Current Literature: Investigating the Relationship between Anti-seizure Medications and Bleeding Disorders: A. Mansoor et al.

Published in:

2025

By:

Mansoor, Areesha;
Shahzad, Maryam;
Zulfiqar, Eeshal;
Ahsan, Muneeba;
Adnan, Rimsha;
Shaeen, Sean Kaisser;
Banatwala, Umm E. Salma Shabbar;
Malikzai, Abdullah

Publication type:

Literature Review

Development and Bioanalytical Validation of RP-HPLC Method for the Simultaneous Determination of Perampanel and Carbamazepine in Human Plasma for Therapeutic Drug Monitoring.

Published in:

Journal of Analytical Chemistry, 2023, v. 78, n. 5, p. 622, doi. 10.1134/S1061934823050076

By:

Said A. Hassan;
Helmy, Aya H.;
Weshahy, Soheir A.;
Youssef, Nadia F.;
El-Zeany, Badr A.

Publication type:

Article

AMPAR inhibition lowers S1P in human blood and improves murine autoimmune neuroinflammation by blocking T cell egress from lymph nodes.

Published in:

Science Translational Medicine, 2025, v. 17, n. 802, p. 1, doi. 10.1126/scitranslmed.ads6434

By:

Wasser, Beatrice;
Ecker, Manuela;
Hanuscheck, Nicholas;
Ellwardt, Erik;
Gärtner, Yvonne;
Engeroff, Kira;
Domingues, Micaela;
Grünewald, Benedikt;
Oshaghi, Mohammadsaleh;
Wollnitzke, Philipp;
Schroeter, Christina B.;
Schmidt, Mirko H. H.;
Muthuraman, Muthuraman;
Levkau, Bodo;
Winter, Yaroslav;
Meuth, Sven G.;
Nitsch, Robert;
von Engelhardt, Jakob;
Bittner, Stefan;
Zipp, Frauke

Publication type:

Article

Perampanel Monotherapy for Focal and Generalized Epilepsy in Clinical Practice.

Published in:

Acta Neurologica Scandinavica, 2023, p. 1, doi. 10.1155/2023/2852853

By:

Chinvarun, Yotin;
Delgado, Rafael Toledano;
Astner-Rohracher, Alexandra;
Wehner, Tim;
Toledo, Manuel;
Matricardi, Sara;
Trinka, Eugen;
Malhotra, Manoj;
Shastri, Oliver;
Villanueva, Vicente

Publication type:

Article

European perspective of perampanel response in people with Intellectual Disability.

Published in:

Acta Neurologica Scandinavica, 2020, v. 142, n. 3, p. 255, doi. 10.1111/ane.13261

By:

Allard, Jon;
Henley, William;
Snoeijen‐Schouwenaars, Francesca;
Ool, Jans;
Tan, In;
Jurgen Schelhaas, H.;
Majoie, Marian H. J. M.;
Hudson, Sharon;
McLean, Brendan;
Shankar, Rohit

Publication type:

Article