Works matching DE "PEPTIDE deformylase"
Results: 16
Safety, tolerability and pharmacokinetics of repeat dosing of the antibiotic GSK1322322, a peptide deformylase inhibitor: a randomized placebo-controlled study.
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- Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 8, p. 1901, doi. 10.1093/jac/dkt097
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New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity.
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- Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 6, p. 1392, doi. 10.1093/jac/dks058
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- Article
How water molecules affect the catalytic activity of hydrolases - A XANES study of the local structures of peptide deformylase.
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- Scientific Reports, 2014, p. 1, doi. 10.1038/srep07453
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Design, Synthesis, and Antibacterial Activities of Novel Heterocyclic Arylsulphonamide Derivatives.
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- Interdisciplinary Sciences: Computational Life Sciences, 2018, v. 10, n. 4, p. 748, doi. 10.1007/s12539-016-0207-2
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A concise synthesis of (±)-methoxyfumimycin ethyl ester.
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- Journal of Chemical Research, 2014, v. 38, n. 6, p. 378, doi. 10.3184/174751914X14011142030158
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The Inhibition and Resistance Mechanisms of Actinonin, Isolated from Marine Streptomyces sp. NHF165, against Vibrio anguillarum.
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- Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.01467
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The effect of food and formulation on the pharmacokinetics, safety, and tolerability of GSK1322322 in healthy volunteers.
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- Clinical Pharmacology in Drug Development, 2015, v. 4, n. 1, p. 49, doi. 10.1002/cpdd.165
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Ligand and Structure-Based Approaches for the Identification of Peptide Deformylase Inhibitors as Antibacterial Drugs.
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- International Journal of Molecular Sciences, 2016, v. 17, n. 7, p. 1141, doi. 10.3390/ijms17071141
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Genome-Wide Identification and in Silico Analysis of Poplar Peptide Deformylases.
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- International Journal of Molecular Sciences, 2012, v. 13, n. 4, p. 5112, doi. 10.3390/ijms13045112
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Peptide deformylase inhibitor actinonin reduces celastrol's HSP70 induction while synergizing proliferation inhibition in tumor cells.
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- BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-146
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Peptide deformylase inhibitor actinonin reduces celastrol's HSP70 induction while synergizing proliferation inhibition in tumor cells.
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- BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-146
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Overexpression of peptide deformylase in breast, colon, and lung cancers.
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- BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-321
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Structure-Based Drug Design of Small Molecule Peptide Deformylase Inhibitors to Treat Cancer.
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- Molecules, 2016, v. 21, n. 4, p. 396, doi. 10.3390/molecules21040396
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Structure and function of a cyanophage-encoded peptide deformylase.
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- ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2013, v. 7, n. 6, p. 1150, doi. 10.1038/ismej.2013.4
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Synthesis of the intermediate for fumimycin: a natural peptide deformylase inhibitor.
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- Research on Chemical Intermediates, 2013, v. 39, n. 7, p. 3049, doi. 10.1007/s11164-012-0817-1
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Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 843, doi. 10.1038/nsmb.2615
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