Works matching DE "PAXILLIN"

Results: 86

Engineered chitosan for improved 3D tissue growth through Paxillin-FAK-ERK activation.

Published in:

Regenerative Biomaterials, 2020, v. 7, n. 2, p. 141, doi. 10.1093/rb/rbz034

By:

Kafi, Md Abdul;
Aktar, Khudishta;
Todo, Mitsugu;
Dahiya, Ravinder

Publication type:

Article

Phosphorylation of paxillin confers cisplatin resistance in non-small cell lung cancer via activating ERK-mediated Bcl-2 expression.

Published in:

Oncogene, 2014, v. 33, n. 35, p. 4385, doi. 10.1038/onc.2013.389

By:

Wu, D-W;
Wu, T-C;
Wu, J-Y;
Cheng, Y-W;
Chen, Y-C;
Lee, M-C;
Chen, C-Y;
Lee, H

Publication type:

Article

Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function.

Published in:

Pulmonary Circulation, 2015, v. 5, n. 4, p. 619, doi. 10.1086/683693

By:

Panfeng Fu;
Usatyuk, Peter V.;
Jacobson, Jeffrey;
Cress, Anne E.;
Garcia, Joe G. N.;
Salgia, Ravi;
Natarajan, Viswanathan

Publication type:

Article

Knockdown of WAVE3 impairs HGF induced migration and invasion of prostate cancer cells.

Published in:

Cancer Cell International, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12935-015-0203-3

By:

Moazzam, Muhammad;
Lin Ye;
Ping-Hui Sun;
Kynaston, Howard;
Jiang, Wen G.

Publication type:

Article

Down-regulated paxillin suppresses cell proliferation and invasion by inhibiting M2 macrophage polarization in colon cancer.

Published in:

Biological Chemistry, 2018, v. 399, n. 11, p. 1285, doi. 10.1515/hsz-2018-0002

By:

Zhang, Ling-li;
Zhang, Lian-feng;
Shi, Yun-bo

Publication type:

Article

Bacterial pathogenesis: UPEC helps host to exfoliate.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 3, p. 159, doi. 10.1038/nrmicro2758

By:

Jermy, Andrew

Publication type:

Article

3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFκB Signaling Pathways.

Published in:

Molecules, 2017, v. 22, n. 4, p. 537, doi. 10.3390/molecules22040537

By:

Wei Chao;
Jeng-Shyan Deng;
Pei-Ying Li;
Yu-Chia Liang;
Guan-Jhong Huang

Publication type:

Article

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

Published in:

Archives of Toxicology, 2013, v. 87, n. 10, p. 1851, doi. 10.1007/s00204-013-1045-1

By:

Kopf, Sabine;
Viola, Katharina;
Atanasov, Atanas;
Jarukamjorn, Kanokwan;
Rarova, Lucie;
Kretschy, Nicole;
Teichmann, Mathias;
Vonach, Caroline;
Saiko, Philipp;
Giessrigl, Benedikt;
Huttary, Nicole;
Raab, Ingrid;
Krieger, Sigurd;
Schumacher, Marc;
Diederich, Marc;
Strnad, Miroslav;
Martin, Rainer;
Szekeres, Thomas;
Jäger, Walter;
Dirsch, Verena

Publication type:

Article

A novel cystathionine γ-lyase inhibitor, I194496, inhibits the growth and metastasis of human TNBC via downregulating multiple signaling pathways.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88355-9

By:

Liu, Ya;
Wang, Lupeng;
Zhang, Xiuli;
Deng, Yuying;
Pan, Limin;
Li, Hui;
Shi, Xiaoyan;
Wang, Tianxiao

Publication type:

Article

Paxillin Promotes Tumor Progression and Predicts Survival and Relapse in Oral Cavity Squamous Cell Carcinoma by MicroRNA-218 targeting.

Published in:

Carcinogenesis, 2014, v. 35, n. 8, p. 1, doi. 10.1093/carcin/bgu102

By:

Wu, De-Wei;
Chuang, Chun-Yi;
Lin, Wea-Long;
Sung, Wen-Wei;
Cheng, Ya-Wen;
Lee, Huei

Publication type:

Article

Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer.

Published in:

Carcinogenesis, 2013, v. 34, n. 4, p. 803, doi. 10.1093/carcin/bgs400

By:

Chen, Dong-Liang;
Wang, De-Shen;
Wu, Wen-Jing;
Zeng, Zhao-Lei;
Luo, Hui-Yan;
Qiu, Miao-Zhen;
Ren, Chao;
Zhang, Dong-Sheng;
Wang, Zhi-Qiang;
Wang, Feng-Hua;
Li, Yu-Hong;
Kang, Tie-Bang;
Xu, Rui-Hua

Publication type:

Article

Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin.

Published in:: Journal of Experimental & Clinical Cancer Research (17569966), 2012, v. 31, n. 1, p. 19, doi. 10.1186/1756-9966-31-19
Publication type:: Article

Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cells.

Published in:

British Journal of Cancer, 2014, v. 111, n. 6, p. 1168, doi. 10.1038/bjc.2014.421

By:

D'Amato, C;
Rosa, R;
Marciano, R;
D'Amato, V;
Formisano, L;
Nappi, L;
Raimondo, L;
Di Mauro, C;
Servetto, A;
Fulciniti, F;
Cipolletta, A;
Bianco, C;
Ciardiello, F;
Veneziani, B M;
De Placido, S;
Bianco, R

Publication type:

Article

Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancer.

Published in:

Journal of Translational Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1479-5876-11-277

By:

Dong-liang Chen;
Zhi-qiang Wang;
Chao Ren;
Zhao-lei Zeng;
De-shen Wang;
Hui-yan Luo;
Feng Wang;
Miao-zhen Qiu;
Long Bai;
Dong-sheng Zhang;
Feng-hua Wang;
Yu-hong Li;
Rui-hua Xu

Publication type:

Article

The roles of Wnt5a, JNK and paxillin in the occurrence of metastasis of pancreatic adenocarcinoma.

Published in:

International Journal of Clinical Oncology, 2014, v. 19, n. 6, p. 1011, doi. 10.1007/s10147-013-0648-0

By:

Lu, Wenli;
Wei, Wei;
Bock, Geertruida;
Zhou, Hongyuan;
Li, Qiang;
Shen, Xiaohong

Publication type:

Article

AZD0530 sensitizes drug-resistant ALK-positive lung cancer cells by inhibiting SRC signaling.

Published in:

FEBS Open Bio, 2017, v. 7, n. 4, p. 472, doi. 10.1002/2211-5463.12162

By:

Zhao, Yi;
Yang, Yi;
Xu, Yunhua;
Lu, Shun;
Jian, Hong

Publication type:

Article

Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase.

Published in:

Oncogene, 1999, v. 18, n. 11, p. 1975, doi. 10.1038/sj.onc.1202514

By:

Murakami, Hideki;
Iwashita, Toshihide;
Asai, Naoya;
Iwata, Yosuke;
Narumiya, Shuh;
Takahashi, Masahide

Publication type:

Article

Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer.

Published in:

Cell Death & Differentiation, 2015, v. 22, n. 5, p. 779, doi. 10.1038/cdd.2014.170

By:

Wu, D-W;
Huang, C-C;
Chang, S-W;
Chen, T-H;
Lee, H

Publication type:

Article

Evolution and Expression of Paxillin Genes in Teleost Fish.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0165266

By:

Jacob, Andrew E.;
Turner, Christopher E.;
Amack, Jeffrey D.

Publication type:

Article

Highly Multiplexed Imaging Uncovers Changes in Compositional Noise within Assembling Focal Adhesions.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160591

By:

Harizanova, Jana;
Fermin, Yessica;
Malik-Sheriff, Rahuman S.;
Wieczorek, Jakob;
Ickstadt, Katja;
Grecco, Hernán E.;
Zamir, Eli

Publication type:

Article

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150323

By:

Hirth, Sofia;
Bühler, Anja;
Bührdel, John B.;
Rudeck, Steven;
Dahme, Tillman;
Rottbauer, Wolfgang;
Just, Steffen

Publication type:

Article

Deciphering Mode of Action of Functionally Important Regions in the Intrinsically Disordered Paxillin (Residues 1-313) Using Its Interaction with FAT (Focal Adhesion Targeting Domain of Focal Adhesion Kinase).

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0150153

By:

Neerathilingam, Muniasamy;
Bairy, Sneha G.;
Mysore, Sumukh

Publication type:

Article

A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction1.

Published in:

Canadian Journal of Physiology & Pharmacology, 2015, v. 93, n. 2, p. 129, doi. 10.1139/cjpp-2014-0388

By:

Zhang, Wenwu;
Huang, Youliang;
Wu, Yidi;
Gunst, Susan J.

Publication type:

Article

Guidance of Axons by Local Coupling of Retrograde Flow to Point Contact Adhesions.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 7, p. 2267, doi. 10.1523/JNEUROSCI.2645-15.2016

By:

Nichol IV, Robert H.;
Hagen, Kate M.;
Lumbard, Derek C.;
Dent, Erik W.;
Gómez, Timothy M.

Publication type:

Article

Extracellular Matrix Elasticity Regulates Osteocyte Gap Junction Elongation: Involvement of Paxillin in Intracellular Signal Transduction.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 51, n. 3, p. 1013, doi. 10.1159/000495482

By:

Zhang, Demao;
Zhou, Chenchen;
Wang, Qingxuan;
Cai, Linyi;
Du, Wei;
Li, Xiaobing;
Zhou, Xuedong;
Xie, Jing

Publication type:

Article

Thapsigargin induces apoptosis of prostate cancer through cofilin-1 and paxillin.

Published in:

Oncology Letters, 2018, v. 16, n. 2, p. 1975, doi. 10.3892/ol.2018.8833

By:

Huang, FENgyu;
Wang, Peitao;
Wang, XinshENg

Publication type:

Article

Paxillin expression is closely linked to the pathogenesis, progression and prognosis of gastric carcinomas.

Published in:

Oncology Letters, 2014, v. 7, n. 1, p. 189, doi. 10.3892/ol.2013.1686

By:

LI-JUN XIAO;
EN-HONG ZHAO;
SHUANG ZHAO;
XIN ZHENG;
HUA-CHUAN ZHENG;
YASUO TAKANO;
HONG-RU SONG

Publication type:

Article

Contributions of KATP and KCa channels to cerebral arteriolar dilation to hypercapnia in neonatal brain.

Published in:

Physiological Reports, 2014, v. 2, n. 8, p. n/a, doi. 10.14814/phy2.12127

By:

Nnorom, Chukwuma C.;
Davis, Corinne;
Fedinec, Alexander L.;
Howell, Khadesia;
Jaggar, Jonathan H.;
Parfenova, Helena;
Pourcyrous, Massroor;
Leffler, Charles W.

Publication type:

Article

Systems pharmacology of mifepristone (RU486) reveals its 47 hub targets and network: Comprehensive analysis and pharmacological focus on FAK-Src-Paxillin complex.

Published in:

Scientific Reports, 2015, p. 7830, doi. 10.1038/srep07830

By:

Yu, Suhong;
Yang, Xingtian;
Zhu, Yewei;
Xie, Fangwei;
Lu, Yusheng;
Yu, Ting;
Yan, Cuicui;
Shao, Jingwei;
Gao, Yu;
Mo, Fan;
Cai, Guoneng;
Sinko, Patrick J.;
Jia, Lee

Publication type:

Article

FAK and paxillin dynamics at focal adhesions in the protrusions of migrating cells.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06024

By:

Ying-Li Hu;
Shaoying Lu;
Szeto, Kai W.;
Jie Sun;
Yingxiao Wang;
Lasheras, Juan C.;
Shu Chien

Publication type:

Article

The ATP-dependent RNA helicase, DDX42 interacts with paxillin and regulates apoptosis and polarization of Ba/F3 cells.

Published in:

Animal Cells & Systems, 2019, v. 23, n. 1, p. 1, doi. 10.1080/19768354.2019.1567580

By:

Sohn, Sung Oh;
Chay, Kee Oh

Publication type:

Article

Interaction with the Paxillin LD1 Motif Relieves MEKK2 Auto-inhibition.

Published in:

Journal of Molecular Signaling, 2015, p. 1, doi. 10.5334/1750-2187-10-4

By:

Kahle, Michael P.;
Cuevas, Bruce D.

Publication type:

Article

Neuropilin-1 enforces extracellular matrix signalling via ABL1 to promote angiogenesis.

Published in:

Biochemical Society Transactions, 2014, v. 42, n. 5, p. 1429, doi. 10.1042/BST20140141

By:

Raimondi, Claudio

Publication type:

Article

MEKK2 regulates paxillin ubiquitylation and localization in MDA-MB 231 breast cancer cells.

Published in:

Biochemical Journal, 2014, v. 464, n. 1, p. 99, doi. 10.1042/BJ20140420

By:

Ameka, Magdalene;
Kahle, Michael P.;
Perez-Neut, Mathew;
Gentile, Saverio;
Mirza, Ahmed A.;
Cuevas, Bruce D.

Publication type:

Article

Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47722-3

By:

Rajah, Abira;
Boudreau, Colton G.;
Ilie, Alina;
Wee, Tse-Luen;
Tang, Kaixi;
Borisov, Aleksandar Z.;
Orlowski, John;
Brown, Claire M.

Publication type:

Article

Niclosamide reverses adipocyte induced epithelial-mesenchymal transition in breast cancer cells via suppression of the interleukin-6/STAT3 signalling axis.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47707-2

By:

Gyamfi, Jones;
Lee, Yun-Hee;
Min, Byung Soh;
Choi, Junjeong

Publication type:

Article

FAK-Src-paxillin system expression and disease outcome in human neuroblastoma.

Published in:

Pediatric Hematology & Oncology, 2017, v. 34, n. 4, p. 221, doi. 10.1080/08880018.2017.1360969

By:

Kratimenos, Panagiotis;
Koutroulis, Ioannis;
Syriopoulou, Vasiliki;
Michailidi, Christina;
Delivoria-Papadopoulos, Maria;
Klijanienko, Jerzy;
Theocharis, Stamatios

Publication type:

Article

Lysophosphatidic Acid Stimulates Activation of Focal Adhesion Kinase and Paxillin and Promotes Cell Motility, via LPA1–3, in Human Pancreatic Cancer.

Published in:

Digestive Diseases & Sciences, 2013, v. 58, n. 12, p. 3524, doi. 10.1007/s10620-013-2878-4

By:

Liao, Yan;
Mu, Ganggang;
Zhang, Lingli;
Zhou, Wei;
Zhang, Jun;
Yu, Honggang

Publication type:

Article

Cell migration: A force to be reckoned with.

Published in:

Nature Physics, 2014, v. 10, n. 9, p. 626, doi. 10.1038/nphys3074

By:

Hunter, Miranda V.;
Fernandez-Gonzalez, Rodrigo

Publication type:

Article

Distinct signaling mechanisms regulate migration in unconfined versus confined spaces.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 5, p. 807, doi. 10.1083/jcb.201302132

By:

Wei-Chien Hung;
Shih-Hsun Chen;
Paul, Colin D.;
Stroka, Kimberly M.;
Ying-Chun Lo;
Yang, Joy T.;
Konstantopoulos, Konstantinos

Publication type:

Article

Essential role for paxillin tyrosine phosphorylation in LPS-induced mitochondrial fission, ROS generation and lung endothelial barrier loss.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97006-y

By:

Fu, Panfeng;
Epshtein, Yulia;
Ramchandran, Ramaswamy;
Mascarenhas, Joseph B.;
Cress, Anne E.;
Jacobson, Jeffrey;
Garcia, Joe G. N.;
Natarajan, Viswanathan

Publication type:

Article

HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/426138

By:

Shibanuma, Motoko;
Mori, Kazunori;
Nose, Kiyoshi

Publication type:

Article

Evaluation of paxillin expression in patients with oral squamous cell carcinoma: An immunohistochemical study.

Published in:

Journal of Oral & Maxillofacial Pathology (0973029X), 2017, v. 21, n. 2, p. 336, doi. 10.4103/jomfp.JOMFP_98_17

By:

Shekhar, Saurabh;
Angadi, Punnya V.

Publication type:

Article

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 11, p. 3785, doi. 10.1083/jcb.201701176

By:

Böttcher, Ralph T.;
Veelders, Maik;
Rombaut, Pascaline;
Faix, Jan;
Theodosiou, Marina;
Stradal, Theresa E.;
Rottner, Klemens;
Zent, Roy;
Herzog, Franz;
Fässler, Reinhard

Publication type:

Article

Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes.

Published in:

Journal of Cell Biology, 2016, v. 213, n. 5, p. 585, doi. 10.1083/jcb.201510036

By:

Petropoulos, Christos;
Oddou, Christiane;
Emadali, Anouk;
Hiriart-Bryant, Edwige;
Boyault, Cyril;
Faurobert, Eva;
Vande Pol, Scott;
Kim-Kaneyama, Joo-ri;
Kraut, Alexandra;
Coute, Yohann;
Block, Marc;
Albiges-Rizo, Corinne;
Destaing, Olivier

Publication type:

Article

Paxillin and carbonic anhydrase IX are prognostic markers in gallbladder squamous cell/adenosquamous carcinomas and adenocarcinomas.

Published in:

Histopathology, 2014, v. 64, n. 7, p. 921, doi. 10.1111/his.12341

By:

Liu, Ziru;
Yang, Zhulin;
Jiang, Song;
Zou, Qiong;
Yuan, Yuan;
Li, Jinghe;
Li, Daiqiang;
Liang, Lufeng;
Chen, Meigui;
Chen, Senlin

Publication type:

Article

The Number of Lines a Cell Contacts and Cell Contractility Drive the Efficiency of Contact Guidance.

Published in:

Cellular & Molecular Bioengineering, 2014, v. 7, n. 1, p. 122, doi. 10.1007/s12195-013-0299-2

By:

Romsey, Nicholas;
Hou, Yue;
Lara Rodriguez, Laura;
Schneider, Ian

Publication type:

Article

Proximity biotinylation provides insight into the molecular composition of focal adhesions at the nanometer scale.

Published in:

Science Signaling, 2016, v. 9, n. 432, p. 1, doi. 10.1126/scisignal.aaf3572

By:

Jing-Ming Dong;
Felicia Pei-Ling Tay;
Hannah Lee-Foon Swa;
Gunaratne, Jayantha;
Thomas Leung;
Burke, Brian;
Manser, Ed

Publication type:

Article

Paxillin contracts the osteoclast cytoskeleton.

Published in:

Journal of Bone & Mineral Research, 2012, v. 27, n. 12, p. 2490, doi. 10.1002/jbmr.1706

By:

Zou, Wei;
DeSelm, Carl J;
Broekelmann, Thomas J;
Mecham, Robert P;
Vande Pol, Scott;
Choi, Kyunghee;
Teitelbaum, Steven L

Publication type:

Article

Paxillin and focal adhesion kinase colocalise in human skeletal muscle and its associated microvasculature.

Published in:

Histochemistry & Cell Biology, 2014, v. 142, n. 3, p. 245, doi. 10.1007/s00418-014-1212-3

By:

Wilson, Oliver;
Bradley, Helen;
Shaw, Christopher;
Wagenmakers, Anton

Publication type:

Article