Works about P53 protein

Results: 3307

Molecular mechanisms of arecoline-induced oral cancer: a network toxicology and molecular docking techniques integrated analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02659-0

By:

Leng, Linghan;
Wang, Xin;
Wang, Hao;
Hu, Yingchun;
Deng, Yaxing;
Wang, Chenglin

Publication type:

Article

Curcumin-Etoposide Synergy: Unveiling the Molecular Mechanisms of Enhanced Apoptosis and Chemoresistance Attenuation in Breast Cancer.

Published in:

IJ Pharmaceutical Research (IJPR), 2024, v. 23, n. 1, p. 1, doi. 10.5812/ijpr-150978

By:

Asl, Bahar Jaberian;
Afarin, Reza;
Hatami, Mahdi;
Madiseh, Amineh Dehghani;
Roshanazadeh, Mohammadreza;
Rashidi, Mojtaba

Publication type:

Article

STUDY OF CARCINOMA OF BREAST WITH REFERENCE TO HISTOLOGICAL GRADING AND ITS CORRELATION WITH P53 AND KI-67 IMMUNOMARKERS.

Published in:

International Journal of Medicine & Public Health, 2025, v. 15, n. 2, p. 232, doi. 10.70034/ijmedph.2025.2.40

By:

Zahir, Begum Bilkish;
Tripathy, Reshmarani;
Pradhan, Chetana;
Patra, Satotsna

Publication type:

Article

The Role of Photobiomodulation Therapy in Reducing Stress-Induced Changes in the Hippocampus of Rats during Septoplasty Modeling.

Published in:

Doklady Biochemistry & Biophysics, 2025, v. 521, n. 1, p. 187, doi. 10.1134/S1607672924601033

By:

Kotov, V. N.;
Kastyro, I. V.;
Ganshin, I. B.;
Popadyuk, V. I.;
Dragunova, S. G.;
Khodorovich, O. S.;
Kartasheva, A. F.;
Barannik, M. I.;
Sarygin, P. V.

Publication type:

Article

The Value of Integrating Hormone Receptors into Immunohistochemistry-Based Simplified Molecular Classification in Endometrial Cancer.

Published in:

Cancer Management & Research, 2025, v. 17, p. 869, doi. 10.2147/CMAR.S514680

By:

Zhao, Shuangshuang;
Yan, Ye;
Wang, Tianqi;
Zhang, Jingying;
Zheng, Xingyu;
Li, Xianxian;
Zhao, Jianzhen;
Yang, Eryan;
Zhao, Xue;
Tian, Lina;
Xue, Fengxia;
Tian, Wenyan;
Wang, Yingmei

Publication type:

Article

Ferroptosis as a therapeutic vulnerability in MDM2 inhibition in dedifferentiated liposarcoma.

Published in:

Oncology Letters, 2025, v. 29, n. 6, p. N.PAG, doi. 10.3892/ol.2025.15015

By:

Yen, Chueh-Chuan;
Chen, Paul Chih-Hsueh;
Chen, San-Chi;
Wu, Wen-Chi;
Yen, Chiao-Han;
Lin, Yung-Chan;
Wu, Po-Kuei;
Chen, Chao-Ming;
Wang, Jir-You;
Chao, Ta-Chung;
Yang, Muh-Hwa;
Fletcher, Jonathan A.

Publication type:

Article

TP53 mutation and immunohistochemical p53 expression characteristics in diffuse large B–cell lymphoma.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1550207

By:

Jin, Yiping;
Wang, Yi;
Wang, Lu;
Zhang, He;
Ren, Beibei;
Zheng, Jiawen;
Xia, Qingxin;
Liu, Yanyan

Publication type:

Article

Circulating mediators linking cardiometabolic diseases to HFpEF: a mediation Mendelian randomization analysis.

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02738-0

By:

Lin, Mingzhi;
Guo, Jiuqi;
Tao, Hongqian;
Gu, Zhilin;
Tang, Wenyi;
Zhou, Fuliang;
Jiang, Yanling;
Zhang, Ruyi;
Jia, Dalin;
Sun, Yingxian;
Jia, Pengyu

Publication type:

Article

Potential effects of hesperidin isolated from Zanthoxylum rhetsa against NTERA-2 cancer stem cells.

Published in:

Indian Journal of Biochemistry & Biophysics, 2025, v. 62, n. 5, p. 502, doi. 10.56042/ijbbv6i5.13921

By:

Ha Phuong Trieu;
Thi Nga Nguyen;
Le Nam Khanh Tran;
Thi Cuc Nguyen;
Thi Phuong Do;
Hoang Ngan Ha Le;
Phuong Nga Nguyen;
Thi Hong Van Nguyen;
Trung Nam Nguyen;
Hoang Ha Chu;
Thi Thao Do

Publication type:

Article

MDM2 Knockdown Reduces the Oncogenic Activities and Enhances NIS Protein Abundance in Papillary Thyroid Cancer.

Published in:

Cancer Genomics & Proteomics (1109-6535), 2025, v. 22, n. 3, p. 444, doi. 10.21873/cgp.20512

By:

DANIEL HUENG‐YUAN SHEN;
HUNG‐PING CHAN;
FU‐REN TSAI;
YU‐LI CHIU;
TSUNG‐JUNG LIANG;
YUNYING SHE;
AN‐CHI LIU;
HUI‐YING YEH;
KUO‐WANG TSAI;
SUNG‐CHOU LI

Publication type:

Article

扶正软坚抗癌方调控Akt/MDM2/P53信号通路对肝癌HepG2细胞恶性生物学行为的影响.

Published in:

Journal of Jilin University (Medicine Edition), 2024, v. 50, n. 6, p. 1654, doi. 10.13481/j.1671⁃587X.20240619

By:

娄静;
赵雷;
朱岩洁;
袁帅强;
王菲;
张杭洲;
徐娇娇;
余晓珂;
侯留法

Publication type:

Article

Combinatorial biosynthesis of novel gentamicin derivatives with nonsense mutation readthrough activity and low cytotoxicity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1575840

By:

Yang, Lihua;
Zhai, Hang;
Tian, Tingting;
Liu, Botong;
Ni, Xianpu;
Xia, Huanzhang

Publication type:

Article

AI-Driven Strategies for Analyzing TP53 Mutations: Detection and Structural Implications.

Published in:

Engineering Letters, 2025, v. 33, n. 5, p. 1203

By:

Arumugam, Aruna;
Masood, Mohamed Divan

Publication type:

Article

Limiting surveillance in individuals with the Palestinian TP53 p. R181C founder variant—is it too soon to draw conclusions?

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 5, p. 819, doi. 10.1093/jnci/djaf009

By:

Omran, Meis;
Malkin, David

Publication type:

Article

TP53 missense allele predisposing to high risk of breast cancer but not pediatric cancers.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 5, p. 1069, doi. 10.1093/jnci/djae334

By:

Lolas-Hamameh, Suhair;
Lieberman, Sari;
Sarahneh, Alaa;
Walsh, Tom;
Lee, Ming K;
Gulsuner, Suleyman;
Rabie, Grace;
Beeri, Rachel;
Aburayyan, Amal;
Mandell, Jessica B;
Fridman, Hila;
Lazer-Derbeko, Galit;
Klopstock, Tehila;
Freireich, Orit;
Lahad, Amnon;
King, Mary-Claire;
Levy-Lahad, Ephrat;
Kanaan, Moien N

Publication type:

Article

The impact of mutations on TP53 protein and MicroRNA expression in HNSCC: Novel insights for diagnostic and therapeutic strategies.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0307859

By:

Mahmoud, Ashraf Attia;
Raih, Mohd Firdaus;
Sage, Edison Eukun;
Ali, Qurashi M.;
Suliman, Omnia H.;
Ibrahim, Sabah A. E.;
Mohamed, Osama;
Abdelrazeg, Samar;
Mohamed, Sofia B.

Publication type:

Article

Restoration of TP53 strategy via specific nanoparticles for ovarian cancer therapy.

Published in:

Journal of Ovarian Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13048-025-01672-9

By:

Zhang, Menglei;
Gu, Yuanyuan;
Shen, Fang;
Gong, Yingxin;
Gu, Zheng;
Hua, Keqin;
Zhou, Guannan;
Ding, Jingxin

Publication type:

Article

Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.pcbi.1012382

By:

Osbourne, Romani;
Thayer, Kelly M.

Publication type:

Article

Allele frequency in thyroid cancer: mechanisms, challenges, and applications in cancer therapy.

Published in:

Thyroid Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13044-025-00237-8

By:

Huang, Jiayu;
Wang, Jiazhi;
Wang, Guangzhi;
Zhao, Yongfu

Publication type:

Article

Expression and possible role of hPTTG1/securin in cutaneous malignant melanoma.

Published in:

Modern Pathology, 2006, v. 19, n. 9, p. 1170, doi. 10.1038/modpathol.3800627

By:

Winnepenninckx, Véronique;
Debiec-Rychter, Maria;
Beliën, Jeroen A. M.;
Fiten, Pierre;
Michiels, Stefan;
Lazar, Vladimir;
Opdenakker, Ghislain;
Meijer, Gerrit A.;
Spatz, Alain;
van den Oord, Joost J.

Publication type:

Article

Combined expression of p53, cyclin D1 and epidermal growth factor receptor improves estimation of prognosis in curatively resected oral cancer.

Published in:

Modern Pathology, 2005, v. 18, n. 11, p. 1482, doi. 10.1038/modpathol.3800455

By:

Shiraki, Masayuki;
Odajima, Tetsuyo;
Ikeda, Tatsuru;
Sasaki, Aya;
Satoh, Masaaki;
Yamaguchi, Akira;
Noguchi, Makoto;
Nagai, Itaru;
Hiratsuka, Hiroyoshi

Publication type:

Article

Molecular characterization of uterine clear cell carcinoma.

Published in:

Modern Pathology, 2004, v. 17, n. 5, p. 530, doi. 10.1038/modpathol.3800057

By:

Hee-Jung An, Giuseppe;
Logani, Sanjay;
Isacson, Christina;
Ellenson, Lora H.

Publication type:

Article

Neoplasms of the Ampulla of Vater with Concurrent Pancreatic Intraductal Neoplasia: A Histological and Molecular Study.

Published in:

Modern Pathology, 2001, v. 14, n. 3, p. 139, doi. 10.1038/modpathol.3880270

By:

Agoff, S. Nicholas;
Crispin, David A.;
Bronner, Mary P.;
Dail, David H.;
Hawes, Stephen E.;
Haggitt, Rodger C.

Publication type:

Article

Prognostic Values of Stromal Proportion and PCNA, Ki-67, and p53 Proteins in Patients with Resected Adenocarcinoma of the Lung.

Published in:

Modern Pathology, 2000, v. 13, n. 5, p. 511, doi. 10.1038/modpathol.3880089

By:

Demarchi, Léa Maria Macruz Ferreira;
Reis, Márcia Martins;
Palomino, Suely Aparecida Pinheiro;
Farhat, Cecília;
Takagaki, Teresa Y.;
Beyruti, Ricardo;
Saldiva, Paulo Hilário Nascimento;
Capelozzi, Vera Luiza

Publication type:

Article

Irradiation Selects for p53-Deficient Hematopoietic Progenitors.

Published in:

PLoS Biology, 2010, v. 8, n. 3, p. 1, doi. 10.1371/journal.pbio.1000324

By:

Marusyk, Andriy;
Porter, Christopher C.;
Zaberezhnyy, Vadym;
DeGregori, James

Publication type:

Article

Structural Insights into the Regulation of a Key Tumor Suppressor.

Published in:

PLoS Biology, 2006, v. 4, n. 2, p. e40, doi. 10.1371/journal.pbio.0040040

By:

Gross, Liza

Publication type:

Article

Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR8 Peptide/p53 DNA for Cocktail Therapy.

Published in:

Advanced Functional Materials, 2014, v. 23, n. 48, p. 6068, doi. 10.1002/adfm.201300793

By:

Wang, Huiyuan;
Guo, Qianqian;
Jiang, Yifan;
Liu, Ergang;
Zhao, Yongxing;
Wang, Huixin;
Li, Yaping;
Huang, Yongzhuo

Publication type:

Article

NMR structure of a complex between MDM2 and a small molecule inhibitor.

Published in:

Journal of Biomolecular NMR, 2004, v. 30, n. 2, p. 163, doi. 10.1023/B:JNMR.0000048856.84603.9b

By:

Fry, David C.;
Emerson, S. Donald;
Palme, Stefan;
Vu, Binh T.;
Liu, Chao-Min;
Podlaski, Frank

Publication type:

Article

Letter to the Editor: 1H, 13C and 15N Resonance Assignments of the Region 1463-1617 of the Mouse p53 Binding Protein 1 (53BP1).

Published in:

Journal of Biomolecular NMR, 2004, v. 28, n. 3, p. 303, doi. 10.1023/B:JNMR.0000013688.79211.8c

By:

Charier, Gaëlle;
Alpha-Bazin, Béatrice;
Coupri, Joël;
Callebaut, Isabelle;
Bérenguer, Frédéric;
Quémeneur, Eric;
Gilquin, Bernard;
Zinn-Justin, Sophie

Publication type:

Article

Effect of irbesartan on development of atrial fibrosis and atrial fibrillation in a canine atrial tachycardia model with left ventricular dysfunction, association with p53.

Published in:

Heart & Vessels, 2016, v. 31, n. 12, p. 2053, doi. 10.1007/s00380-016-0853-7

By:

Kataoka, Naoya;
Nishida, Kunihiro;
Kinoshita, Koshi;
Sakamoto, Tamotsu;
Nakatani, Yosuke;
Tsujino, Yasushi;
Mizumaki, Koichi;
Inoue, Hiroshi;
Kinugawa, Koichiro

Publication type:

Article

The prognostic value of p53 and DNA ploidy following radical prostatectomy.

Published in:

World Journal of Urology, 2003, v. 21, n. 3, p. 171, doi. 10.1007/s00345-003-0345-0

By:

Deliveliotis, C.;
Skolarikos, A.;
Karayannis, A.;
Tzelepis, V.;
Trakas, N.;
Alargof, E.;
Protogerou, V.

Publication type:

Article

DFT calculations of electronic structure evaluation and intermolecular interactions of p53-derived peptides with cytotoxic effect on breast cancer.

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2021, v. 140, n. 8, p. 1, doi. 10.1007/s00214-021-02822-0

By:

Barrientos-Salcedo, Carolina;
Lara-Rodríguez, Maricarmen;
Campos-Fernández, Linda;
Legorreta-Herrera, Martha;
Soto-Cruz, Isabel;
Soriano-Correa, Catalina

Publication type:

Article

Anaplastic histology Wilms' tumors registered to the Japan Wilms' Tumor Study Group are less aggressive than that in the National Wilms' Tumor Study 5.

Published in:

2016

By:

Oue, Takaharu;
Koshinaga, Tsugumichi;
Takimoto, Tetsuya;
Okita, Hajime;
Tanaka, Yukichi;
Nozaki, Miwako;
Haruta, Masayuki;
Kaneko, Yasuhiko;
Fukuzawa, Masahiro;
Renal Tumor Committee of the Japanese Children’s Cancer Group

Publication type:

journal article

Apoptosis induction in human cancer cells by sungucine from Strychnos icaja root.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 367, n. 3, p. 260, doi. 10.1007/s00210-003-0691-x

By:

Frederich, Michel;
Bentires-Ali, Mohamed;
Tits, Monique;
Angenot, Luc;
Heinen, Ernst;
De Pauw-Gillet, Marie-Claire

Publication type:

Article

18F-fluorodeoxyglucose positron emission tomography in patients with recurrent ovarian cancer: in comparison with vascularity, Ki-67, p53, and histologic grade.

Published in:

2007

By:

Cho, Song-Mee;
Park, Yong;
Lee, Joon Mo;
Byun, Jae Young;
Lee, Jae Mun;
Lee, Kyo-Young;
Park, Gyeong-Sin;
Kim, Hyeon-Sook;
Lee, Bae Young;
Lee, Kang-Hoon;
Song, Kyung-Sup;
Park, Yong Gyu

Publication type:

journal article

Clinical features and prognostic significance of tumor involved with subventricular zone in pediatric glioblastoma: a 10-year experience in a single hospital.

Published in:

Child's Nervous System, 2022, v. 38, n. 8, p. 1469, doi. 10.1007/s00381-022-05522-7

By:

Jiao, Yang;
Wang, Meng;
Liu, Xueyou;
Wang, Junkuan;
Shou, Yuwei;
Sun, Hongwei

Publication type:

Article

Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1449, doi. 10.1007/s00280-011-1641-9

By:

Xavier, Cristina;
Lima, Cristovao;
Rohde, Mikkel;
Pereira-Wilson, Cristina

Publication type:

Article

Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 2, p. 513, doi. 10.1007/s00280-010-1518-3

By:

Jia, Lee;
Gorman, Gregory;
Coward, Lori;
Noker, Patricia;
McCormick, David;
Horn, Thomas;
Harder, J.;
Muzzio, Miguel;
Prabhakar, Bellur;
Ganesh, Balaji;
Das Gupta, Tapas;
Beattie, Craig

Publication type:

Article

p53-dependent anticancer effects of leptomycin B on lung adenocarcinoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 6, p. 1369, doi. 10.1007/s00280-010-1434-6

By:

Shao, Changxia;
Lu, Chuanwen;
Chen, Lixia;
Koty, Patrick;
Cobos, Everardo;
Gao, Weimin

Publication type:

Article

Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 4, p. 687, doi. 10.1007/s00280-009-1074-x

By:

Nigam, Nidhi;
George, Jasmine;
Srivastava, Smita;
Roy, Preeti;
Bhui, Kulpreet;
Singh, Madhulika;
Shukla, Yogeshwer

Publication type:

Article

The p53 codon 72 (Arg72Pro) polymorphism is associated with the degree of insulin resistance in type 2 diabetic subjects: a cross-sectional study.

Published in:

Acta Diabetologica, 2013, v. 50, n. 3, p. 429, doi. 10.1007/s00592-012-0450-x

By:

Bonfigli, Anna;
Sirolla, Cristina;
Testa, Roberto;
Cucchi, Michela;
Spazzafumo, Liana;
Salvioli, Stefano;
Ceriello, Antonio;
Olivieri, Fabiola;
Festa, Roberto;
Procopio, Antonio;
Brandoni, Gabriele;
Boemi, Massimo;
Marra, Maurizio;
Franceschi, Claudio

Publication type:

Article

Lack of functional p53 renders DENSpm-induced autophagy and apoptosis in time dependent manner in colon cancer cells.

Published in:

Amino Acids, 2015, v. 47, n. 1, p. 87, doi. 10.1007/s00726-014-1851-7

By:

Çoker-Gürkan, Ajda;
Arisan, Elif;
Obakan, Pınar;
Palavan-Unsal, Narçin

Publication type:

Article

A bursal pentapeptide (BPP-I), a novel bursal-derived peptide, exhibits antiproliferation of tumor cell and immunomodulator activity.

Published in:

Amino Acids, 2012, v. 42, n. 6, p. 2215, doi. 10.1007/s00726-011-0961-8

By:

Feng, Xiu;
Liu, Qing;
Cao, Rui;
Zhou, Bin;
Wang, Fang;
Deng, Wen;
Qiu, Ya;
Zhang, Yu;
Ishag, Hassan;
Ma, Zhi;
Zheng, Qi;
Chen, Pu

Publication type:

Article

Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53.

Published in:

Amino Acids, 2011, v. 41, n. 4, p. 863, doi. 10.1007/s00726-010-0497-3

By:

Berge, Gisle;
Mælandsmo, Gunhild

Publication type:

Article

Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma.

Published in:

Amino Acids, 2011, v. 41, n. 4, p. 875, doi. 10.1007/s00726-010-0514-6

By:

Berge, Gisle;
Costea, Daniela;
Berg, Marianne;
Rasmussen, Heidi;
Grotterød, Ida;
Lothe, Ragnhild;
Mælandsmo, Gunhild;
Flatmark, Kjersti

Publication type:

Article

S100A2 in cancerogenesis: a friend or a foe?

Published in:

Amino Acids, 2011, v. 41, n. 4, p. 849, doi. 10.1007/s00726-010-0623-2

By:

Wolf, Susann;
Haase-Kohn, Cathleen;
Pietzsch, Jens

Publication type:

Article

A Six-Week Course of Bacillus Calmette-Guérin Prophylaxis Is Insufficient to Prevent Tumor Recurrence in Nonmuscle Invasive Bladder Cancer with Strong-Positive Expression of p53.

Published in:

Oncology, 2011, v. 79, n. 5/6, p. 440, doi. 10.1159/000327214

By:

Jong Jin Oh;
Sang Hyun Ji;
Don Kyoung Choi;
In Hyuk Gong;
Tae Heon Kim;
Dong Soo Park

Publication type:

Article

p53 Mutation Analysis of Low-Grade Dysplasia and High-Grade Dysplasia/Carcinoma in situ of the Esophagus Using Laser Capture Microdissection.

Published in:

Oncology, 2006, v. 71, n. 3/4, p. 237, doi. 10.1159/000106448

By:

Kobayashi, Maki;
Kawachi, Hiroshi;
Takizawa, Toichiro;
Uchida, Keisuke;
Sekine, Masaki;
Kumagai, Jiro;
Momma, Kumiko;
Nemoto, Tetsuo;
Akashi, Takumi;
Funata, Nobuaki;
Eishi, Yoshinobu;
Koike, Morio

Publication type:

Article

TP53 Gene Mutation, an Unfavorable Prognostic Factor for Malignant Lymphomas in Autoimmune Diseases.

Published in:

Oncology, 2005, v. 69, n. 2, p. 175, doi. 10.1159/000087980

By:

Hoshida, Yoshihiko;
Hongyo, Tadashi;
Jing-Xian Xu;
Sasaki, Toru;
Tomita, Yasuhiko;
Nomura, Taisei;
Aozasa, Katsuyuki

Publication type:

Article

Prognostic Relevance of Altered pRb and p53 Protein Expression in Surgically Treated Non-Small Cell Lung Cancer Patients.

Published in:

Oncology, 2004, v. 67, n. 1, p. 60, doi. 10.1159/000080287

By:

Dworakowska, Dorota;
Jassem, Ewa;
Jassem, Jacek;
Wiedorn, Klaus Hermann;
Boltze, Carsten;
Karmolinski, Andrzej;
Dworakowski, Rafal;
Skokowski, Jan;
Jaskiewicz, Kazimierz;
Bosse, Alexander;
Czestochowska, Eugenia

Publication type:

Article