Works about P53 protein

Results: 3357

Early identification of TP53 mutations and TP53 allelic state in myelodysplastic neoplasms and acute myeloid leukemia via point‐of‐care p53 immunohistochemistry.

Published in:

Cancer (0008543X), 2025, v. 131, n. 13, p. 1, doi. 10.1002/cncr.35950

By:

Patel, Shyam A.;
Khedr, Salwa;
Gordon, Caroline D.;
Nuvvula, Sri;
Littman, Noah;
Woda, Bruce;
Hutchinson, Lloyd;
Li, Shaoguang;
Xie, Yiyu;
Selove, William;
Cerny, Jan;
Gerber, Jonathan M.

Publication type:

Article

Transmission ratio distortion of germline TP53 variants in Li–Fraumeni syndrome families.

Published in:

Cancer (0008543X), 2025, v. 131, n. 13, p. 1, doi. 10.1002/cncr.35943

By:

Halpern, Naama;
Kventsel, Iris;
Strauss, Gal;
Peerless, Yehudit;
Boursi, Ben;
Yalon, Michal;
Goldberg, Yael;
Kedar, Inbal;
Shani, Hagit;
Friedman, Eitan;
Bernstein‐Molho, Rinat

Publication type:

Article

Bcl-xL is important for the antiapoptotic activity of Gfi1 and is upregulated by Gfi1 through hemgn.

Published in:

Journal of Immunology, 2025, v. 214, n. 5, p. 1046, doi. 10.1093/jimmun/vkae066

By:

G C, Binod;
Du, Pei;
Zhang, Yangyang;
Yang, Li;
Dong, Fan

Publication type:

Article

Atypical spindle cell/pleomorphic lipomatous tumour: a clinicopathologic, immunohistochemical and molecular study of 55 cases, highlighting TP53 gene alterations as a genetic hallmark of atypical pleomorphic lipomatous tumour.

Published in:

Histopathology, 2025, v. 87, n. 2, p. 197, doi. 10.1111/his.15474

By:

Cordier, Fleur;
Kleijn, Tony G;
Mentzel, Thomas;
Flucke, Uta;
van Gorp, Joost;
Ferdinande, Liesbeth;
Van Belle, Sarah;
Loontiens, Siebe;
Van der Meulen, Joni;
Van Dorpe, Jo;
Cleven, Arjen H G;
Creytens, David

Publication type:

Article

Correlating p53 immunostaining patterns with somatic TP53 mutation and functional properties of mutant p53 in triple‐negative breast cancer.

Published in:

Histopathology, 2025, v. 87, n. 2, p. 299, doi. 10.1111/his.15453

By:

Kim, Meejeong;
Lee, Miseon;
Lee, Ahwon;
Choi, Byung‐Ock;
Park, Woo‐Chan;
Kim, Sung Hun;
Lee, Jieun;
Kang, Jun

Publication type:

Article

The non-metabolic function of 6PGD coordinates CCNA2 and HMGA2 expression to drive colorectal cancer progression and drug response.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03450-3

By:

Sun, Mingming;
Yan, Qi;
Zhai, Xinru;
Dai, Xintong;
Yang, Chenxin;
Zhao, Huifang;
Lai, Sizhen;
Wang, Jiyan;
Li, Lian;
Li, Zhen;
Li, Yanping;
Wang, Taoyuan;
He, Tao;
Xue, Jun;
Jia, Zhenghu;
Zhang, Chunze;
Zhang, Shuai;
Shan, Changliang

Publication type:

Article

The Expressions of Noc2l (NOC2-Like Nucleolar Associated Transcriptional Repressor) and p53 in the Mouse Uterus Through the Peri-Implantation Duration.

Published in:

Bratislava Medical Journal / Bratislavské Lekárske Listy, 2025, v. 126, n. 7, p. 1371, doi. 10.1007/s44411-025-00157-x

By:

Golal, Ezgi;
Balci, Cemre Nur;
Akkan, Simla Su;
Acar, Nuray

Publication type:

Article

Mutation dynamics from diagnosis to relapse in acute myeloid leukemia with chromosomal 7 deletions.

Published in:

Leukemia & Lymphoma, 2025, v. 66, n. 7, p. 1221, doi. 10.1080/10428194.2025.2477723

By:

Kugler, Eitan;
Dasdemir, Enes;
Bataller, Alex;
Wang, Bofei;
DiNardo, Courtney D.;
Daver, Naval;
Yilmaz, Musa;
Short, Nicholas J.;
Borthakur, Gautam;
Kadia, Tapan M.;
Sasaki, Koji;
Hammond, Danielle;
Bazinet, Alexandre;
Irajizad, Ehsan;
Thakral, Beenu;
Pierce, Sherry;
Reville, Patrick;
Ravandi, Farhad;
Abbas, Hussein A.

Publication type:

Article

Bio-engineered microRNA-7 effectively interferes with the Akt3/p53 axis to suppress human non-small cell lung cancer.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03856-1

By:

Huang, Qian;
Chu, Xiaohua;
Yang, Chaofei;
Huai, Ying;
He, Chenyang;
Ma, Xingcong;
Pei, Jiawei;
Gao, Junhong;
Liu, Zhiyong;
Jiang, Shanfeng;
Qian, Airong;
Tian, Ye

Publication type:

Article

Shikonin inhibits epithelial-mesenchymal transition in glioblastoma cells by upregulating p53 and promoting miR-361-5p level to suppress ZEB1 expression.

Published in:

BMC Neuroscience, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12868-025-00956-6

By:

Zhang, Fengying;
Liu, Zhiyi;
Wang, Yingbin;
Zuo, Lin;
Xu, Sicong;
Liu, Yin;
Liang, Hao;
Xue, Yixue

Publication type:

Article

miR-7-5p and Importin-7 Regulate the p53 Dynamics and Stability in Malignant and Benign Thyroid Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5813, doi. 10.3390/ijms26125813

By:

Al-Abdallah, Abeer;
Jahanbani, Iman;
Al-Shammari, Bashayer

Publication type:

Article

Ballota hirsuta Benth Arrests the Cell Cycle, Induces Apoptosis and Inhibits the Invasion of MCF-7 and MDA-MB-231 Cell Lines in 2D and 3D Models.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5672, doi. 10.3390/ijms26125672

By:

Martínez-Méndez, Diana del Carmen;
Sánchez-Mundo, María de la Luz;
Ortiz-León, Laura Adriana;
Álvarez-Salas, Luis Marat;
Rosales-García, Víctor Hugo;
Rodríguez-Campos, Jacobo;
Jaramillo-Flores, María Eugenia

Publication type:

Article

Targeting the p53/xCT/GSH Axis with PRIMA-1 Met Combined with Sulfasalazine Shows Therapeutic Potential in Chronic Lymphocytic Leukemia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5559, doi. 10.3390/ijms26125559

By:

Pasino, Martina;
Speciale, Andrea;
Ravera, Silvia;
Cutrona, Giovanna;
Massara, Rosanna;
Bertola, Nadia;
Viale, Maurizio;
Velkova, Irena;
Mazzarello, Andrea Nicola;
Fais, Franco;
Loiacono, Fabrizio;
Matis, Serena;
Valenti, Giulia Elda;
Traverso, Nicola;
Domenicotti, Cinzia;
Marengo, Barbara;
Tasso, Bruno;
Ibatici, Adalberto;
Angelucci, Emanuele;
Vaisitti, Tiziana

Publication type:

Article

Enhancing the Pharmacological Properties of Triterpenes Through Acetylation: An Anticancer and Antioxidant Perspective.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2661, doi. 10.3390/molecules30122661

By:

Bednarczyk-Cwynar, Barbara;
Ruszkowski, Piotr;
Günther, Andrzej;
Sip, Szymon;
Bednarek-Rajewska, Katarzyna;
Zalewski, Przemysław

Publication type:

Article

Irradiation Selects for p53-Deficient Hematopoietic Progenitors.

Published in:

PLoS Biology, 2010, v. 8, n. 3, p. 1, doi. 10.1371/journal.pbio.1000324

By:

Marusyk, Andriy;
Porter, Christopher C.;
Zaberezhnyy, Vadym;
DeGregori, James

Publication type:

Article

Structural Insights into the Regulation of a Key Tumor Suppressor.

Published in:

PLoS Biology, 2006, v. 4, n. 2, p. e40, doi. 10.1371/journal.pbio.0040040

By:

Gross, Liza

Publication type:

Article

Treatment of Terminal Peritoneal Carcinomatosis by a Transducible p53-Activating Peptide.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 1, doi. 10.1371/journal.pbio.0020036

By:

Snyder, Eric L;
Meade, Bryan R;
Saenz, Cheryl C;
Dowdy, Steven F

Publication type:

Article

Treatment of Terminal Peritoneal Carcinomatosis by a Transducible p53-Activating Peptide.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 0186, doi. 10.1371/journal.pbio.0020036

By:

Snyder, Eric L.;
Meade, Bryan R.;
Saenz, Cheryl C.;
Dowdy, Steven F.

Publication type:

Article

Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.

Published in:

Liver International, 2011, v. 31, n. 4, p. 561, doi. 10.1111/j.1478-3231.2011.02474.x

By:

Gursoy-Yuzugullu, Ozge;
Yuzugullu, Haluk;
Yilmaz, Mustafa;
Ozturk, Mehmet

Publication type:

Article

A Lifelong Journey with the Guardian of the Genome.

Published in:

2013

By:

Ng Yi Zhen

Publication type:

Interview

Protein p53 Binding to Cisplatin-modified DNA Targets Evaluated by Modification-specific Electrochemical Immunoprecipitation Assay.

Published in:

Electroanalysis, 2017, v. 29, n. 2, p. 319, doi. 10.1002/elan.201600480

By:

Tichy, Vlastimil;
Sebest, Peter;
Orsag, Petr;
Havran, Ludek;
Pivonkova, Hana;
Fojta, Miroslav

Publication type:

Article

Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR<sub>8</sub> Peptide/p53 DNA for Cocktail Therapy.

Published in:

Advanced Functional Materials, 2014, v. 23, n. 48, p. 6068, doi. 10.1002/adfm.201300793

By:

Wang, Huiyuan;
Guo, Qianqian;
Jiang, Yifan;
Liu, Ergang;
Zhao, Yongxing;
Wang, Huixin;
Li, Yaping;
Huang, Yongzhuo

Publication type:

Article

Age-dependent copy number variations of TP53 tumour suppressor gene associated with altered phosphorylation status of p53 protein in sporadic schwannomas.

Published in:

Journal of Neuro-Oncology, 2019, v. 143, n. 3, p. 369, doi. 10.1007/s11060-019-03176-1

By:

Chen, Hongsai;
Huang, He;
Zhao, Jingjing;
Wang, Zhigang;
Chang, Mengling;
Xue, Lu;
Zhu, Weidong;
Chai, Yongchuan;
Li, Gen;
Wang, Zhaoyan;
Wu, Hao

Publication type:

Article

TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 1, p. 131, doi. 10.1007/s11060-014-1407-4

By:

Gillet, Emeline;
Alentorn, Agusti;
Doukouré, Brahima;
Mundwiller, Emeline;
Thuij, Hinke;
Reijneveld, Jaap;
Medina, José;
Liou, Amélie;
Marie, Yannick;
Mokhtari, Karima;
Hoang-Xuan, Khê;
Sanson, Marc;
Delattre, Jean-Yves;
Idbaih, Ahmed

Publication type:

Article

Trans-membrane peptide therapy for malignant glioma by use of a peptide derived from the MDM2 binding site of p53.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 1, p. 7, doi. 10.1007/s11060-012-0860-1

By:

Yamada, Sachiko;
Kanno, Hiroshi;
Kawahara, Nobutaka

Publication type:

Article

P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 3, p. 503, doi. 10.1007/s11060-011-0791-2

By:

Bajbouj, K.;
Mawrin, C.;
Hartig, R.;
Schulze-Luehrmann, J.;
Wilisch-Neumann, A.;
Roessner, A.;
Schneider-Stock, R.

Publication type:

Article

p53 expression predicts dismal outcome for medulloblastoma patients with metastatic disease.

Published in:

Journal of Neuro-Oncology, 2012, v. 106, n. 1, p. 135, doi. 10.1007/s11060-011-0648-8

By:

Gessi, Marco;
Bueren, André;
Rutkowski, Stefan;
Pietsch, Torsten

Publication type:

Article

Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.

Published in:

Journal of Neuro-Oncology, 2011, v. 102, n. 1, p. 1, doi. 10.1007/s11060-010-0283-9

By:

Blough, Michael;
Beauchamp, Desiree;
Westgate, Morgan;
Kelly, John;
Cairncross, J.

Publication type:

Article

Pseudoprogression in patients with malignant gliomas treated with concurrent temozolomide and radiotherapy: potential role of p53.

Published in:

Journal of Neuro-Oncology, 2011, v. 102, n. 1, p. 157, doi. 10.1007/s11060-010-0305-7

By:

Kang, Hyun-Cheol;
Kim, Chae-Yong;
Han, Jung;
Choe, Ghee;
Kim, Jae;
Kim, Jee;
Kim, In

Publication type:

Article

Loss of heterozygosity at 1p-19q induces a global change in oligodendroglial tumor gene expression.

Published in:

Journal of Neuro-Oncology, 2009, v. 95, n. 3, p. 343, doi. 10.1007/s11060-009-9944-y

By:

Ferrer-Luna, Rubén;
Mata, Manuel;
Núñez, Lina;
Calvar, Jorge;
Dasí, Francisco;
Arias, Eugenia;
Piquer, José;
Cerdá-Nicolás, Miguel;
Taratuto, Ana;
Sevlever, Gustavo;
Celda, Bernardo;
Martinetto, Horacio

Publication type:

Article

Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes.

Published in:

Journal of Neuro-Oncology, 2009, v. 92, n. 3, p. 357

By:

Sandip Mishra;
Joy Gumin;
Naoki Shinojima;
Raymond Sawaya;
Frederick Lang

Publication type:

Article

Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00537-x

By:

Wang, Bingwu;
Gao, Jian;
Zhao, Zhongjun;
Zhong, Xuefei;
Cui, Hao;
Hou, Hui;
Zhang, Yanping;
Zheng, Junnian;
Di, Jiehui;
Liu, Yong

Publication type:

Article

WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00187-x

By:

Jiang, Shengqun;
Chen, Jiansu

Publication type:

Article

Diepoxybutane induces the p53‐dependent transactivation of the CCL4 gene that mediates apoptosis in exposed human lymphoblasts.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 5, p. 1, doi. 10.1002/jbt.23316

By:

Ewunkem, Akamu J.;
Deve, Maya;
Harrison, Scott H.;
Muganda, Perpetua M.

Publication type:

Article

Blockage of MDM2‐mediated p53 ubiquitination by yuanhuacine restrains the carcinogenesis of prostate carcinoma cells by suppressing LncRNA LINC00665.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 3, p. 1, doi. 10.1002/jbt.23265

By:

Yan, Miao;
Li, Xin;
Gu, Jinbao;
Gao, Guojun;
Wu, Ziyu;
Xue, Peng

Publication type:

Article

miR‐8485 alleviates the injury of cardiomyocytes through TP53INP1.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 10, p. 1, doi. 10.1002/jbt.23159

By:

Luo, Xiuying;
Xu, Yanlin;
Zhong, Ze;
Xiang, Peng;
Wu, Xindong;
Chong, Aiguo

Publication type:

Article

P53 inhibitor pifithrin‐α inhibits ropivacaine‐induced neuronal apoptosis via the mitochondrial apoptosis pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 8, p. 1, doi. 10.1002/jbt.22822

By:

Zeng, Lian;
Zhang, Fuyu;
Zhang, Zhen;
Xu, Min;
Xu, Yang;
Liu, Ying;
Xu, Hongxia;
Sun, Xiaodong;
Sang, Ming;
Luo, Huiyu

Publication type:

Article

Upregulation of iASPP ameliorates hypoxia/reoxygenation‐induced apoptosis and oxidative stress in cardiomyocytes by upregulating Nrf2 signaling.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 3, p. 1, doi. 10.1002/jbt.22686

By:

Bai, Baobao;
Zeng, Guangwei;
Chen, Ruirui;
Ai, Yongfei;
Qiang, Hua

Publication type:

Article

Ethanol exacerbates manganese‐induced oxidative/nitrosative stress, pro‐inflammatory cytokines, nuclear factor‐κB activation, and apoptosis induction in rat cerebellar cortex.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 3, p. 1, doi. 10.1002/jbt.22681

By:

Nkpaa, Kpobari W.;
Owoeye, Olatunde;
Amadi, Benjamin A.;
Adedara, Isaac A.;
Abolaji, Amos O.;
Wegwu, Matthew O.;
Farombi, Ebenezer O.

Publication type:

Article

Curcumin induced apoptosis is mediated through oxidative stress in mutated p53 and wild type p53 colon adenocarcinoma cell lines.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 1, p. 1, doi. 10.1002/jbt.22616

By:

Sritharan, Sruthi;
Sivalingam, Nageswaran

Publication type:

Article

Diepoxybutane induces the expression of a novel p53‐target gene XCL1 that mediates apoptosis in exposed human lymphoblasts.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 3, p. 1, doi. 10.1002/jbt.22446

By:

Ewunkem, Akamu J.;
Deve, Maya;
Harrison, Scott H.;
Muganda, Perpetua M.

Publication type:

Article

Functional analysis of the p53 codon 72 polymorphism in black South Africans with rheumatoid arthritis—a pilot study.

Published in:

Clinical Rheumatology, 2010, v. 29, n. 10, p. 1099, doi. 10.1007/s10067-010-1505-4

By:

Moodley, Devapregasan;
Mody, Girish M.;
Chuturgoon, Anil A.

Publication type:

Article

Usefulness of serum p53 antibody measurement in colorectal cancer: an examination of 1384 primary colorectal cancer patients.

Published in:

Surgery Today, 2014, v. 44, n. 8, p. 1529, doi. 10.1007/s00595-013-0703-5

By:

Yamaguchi, Tetsuji;
Takii, Yasumasa;
Maruyama, Satoshi

Publication type:

Article

Anaplastic histology Wilms' tumors registered to the Japan Wilms' Tumor Study Group are less aggressive than that in the National Wilms' Tumor Study 5.

Published in:

2016

By:

Oue, Takaharu;
Koshinaga, Tsugumichi;
Takimoto, Tetsuya;
Okita, Hajime;
Tanaka, Yukichi;
Nozaki, Miwako;
Haruta, Masayuki;
Kaneko, Yasuhiko;
Fukuzawa, Masahiro;
Renal Tumor Committee of the Japanese Children’s Cancer Group

Publication type:

journal article

Main genetic differences in high-grade gliomas may present different MR imaging and MR spectroscopy correlates.

Published in:

European Radiology, 2021, v. 31, n. 2, p. 749, doi. 10.1007/s00330-020-07138-4

By:

Bernabéu-Sanz, Ángela;
Fuentes-Baile, María;
Alenda, Cristina

Publication type:

Article

p53: son rôle dans les mécanismes de résistance. Sait-on s’en servir en pratique cancérologique en 2005?

Published in:

Oncologie (Tech Science Press), 2005, v. 7, n. 7, p. 574, doi. 10.1007/s10269-005-0290-1

By:

Cals, L.;
Maille, N.;
Sohn, C.;
Tchiknavorian, X.;
Poirot, F.

Publication type:

Article

A Six-Week Course of Bacillus Calmette-Guérin Prophylaxis Is Insufficient to Prevent Tumor Recurrence in Nonmuscle Invasive Bladder Cancer with Strong-Positive Expression of p53.

Published in:

Oncology, 2011, v. 79, n. 5/6, p. 440, doi. 10.1159/000327214

By:

Jong Jin Oh;
Sang Hyun Ji;
Don Kyoung Choi;
In Hyuk Gong;
Tae Heon Kim;
Dong Soo Park

Publication type:

Article

p53 Mutation Analysis of Low-Grade Dysplasia and High-Grade Dysplasia/Carcinoma in situ of the Esophagus Using Laser Capture Microdissection.

Published in:

Oncology, 2006, v. 71, n. 3/4, p. 237, doi. 10.1159/000106448

By:

Kobayashi, Maki;
Kawachi, Hiroshi;
Takizawa, Toichiro;
Uchida, Keisuke;
Sekine, Masaki;
Kumagai, Jiro;
Momma, Kumiko;
Nemoto, Tetsuo;
Akashi, Takumi;
Funata, Nobuaki;
Eishi, Yoshinobu;
Koike, Morio

Publication type:

Article

Molecular mechanisms of arecoline-induced oral cancer: a network toxicology and molecular docking techniques integrated analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02659-0

By:

Leng, Linghan;
Wang, Xin;
Wang, Hao;
Hu, Yingchun;
Deng, Yaxing;
Wang, Chenglin

Publication type:

Article

Systematically investigate the mechanism underlying the therapeutic effect of emodin in treatment of prostate cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02141-x

By:

Yuan, Gang;
Mao, Jingxin;
Li, Zheng

Publication type:

Article