Works about P53 antioncogene

Results: 4451

Early identification of TP53 mutations and TP53 allelic state in myelodysplastic neoplasms and acute myeloid leukemia via point‐of‐care p53 immunohistochemistry.

Published in:

Cancer (0008543X), 2025, v. 131, n. 13, p. 1, doi. 10.1002/cncr.35950

By:

Patel, Shyam A.;
Khedr, Salwa;
Gordon, Caroline D.;
Nuvvula, Sri;
Littman, Noah;
Woda, Bruce;
Hutchinson, Lloyd;
Li, Shaoguang;
Xie, Yiyu;
Selove, William;
Cerny, Jan;
Gerber, Jonathan M.

Publication type:

Article

Methyltransferase 1-mediated tRNA N<sup>7</sup>-methylguanosine modification regulates dentin formation during tooth root development via p53 signaling.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 6, p. 813, doi. 10.1093/jbmr/zjaf056

By:

Gan, Xinyan;
He, Kun;
Xiong, Qiuchan;
Sheng, Rui;
Lei, Kexin;
Jiang, Shuang;
Yang, Xiaoyu;
Cai, Yimeng;
Huang, Denghao;
Shi, Yu;
Ye, Ling;
Yuan, Quan;
Li, Qiwen

Publication type:

Article

The Mdm2-p53 axis links cementocyte survival to cellular cementum volume.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 4, p. 548, doi. 10.1093/jbmr/zjaf025

By:

Tian, Xue;
Yang, Guobin;
Zheng, Huiwen;
Pi, Yixing;
Cao, Zhengguo;
Duan, Peipei;
Chen, Zhi;
Yuan, Guohua

Publication type:

Article

Correlating p53 immunostaining patterns with somatic TP53 mutation and functional properties of mutant p53 in triple‐negative breast cancer.

Published in:

Histopathology, 2025, v. 87, n. 2, p. 299, doi. 10.1111/his.15453

By:

Kim, Meejeong;
Lee, Miseon;
Lee, Ahwon;
Choi, Byung‐Ock;
Park, Woo‐Chan;
Kim, Sung Hun;
Lee, Jieun;
Kang, Jun

Publication type:

Article

Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08413-0

By:

Patel, Divyesh;
Tiusanen, Ville;
Karttunen, Konsta;
Pihlajamaa, Päivi;
Sahu, Biswajyoti

Publication type:

Article

Mutant p53 induces SH3BGRL expression to promote cell engulfment.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02582-x

By:

Dolma, Lobsang;
Patterson, Mary I.;
Banyard, Antonia;
Hall, Callum;
Bell, Steven;
Breitwieser, Wolfgang;
Sahoo, Sudhakar;
Weightman, John;
Gil, Maria Pazos;
Ashton, Garry;
Behan, Caron;
Fullard, Nicola;
Williams, Lewis D.;
Muller, Patricia AJ.

Publication type:

Article

Bio-engineered microRNA-7 effectively interferes with the Akt3/p53 axis to suppress human non-small cell lung cancer.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03856-1

By:

Huang, Qian;
Chu, Xiaohua;
Yang, Chaofei;
Huai, Ying;
He, Chenyang;
Ma, Xingcong;
Pei, Jiawei;
Gao, Junhong;
Liu, Zhiyong;
Jiang, Shanfeng;
Qian, Airong;
Tian, Ye

Publication type:

Article

Isolation and Bioactivities of Secondary Metabolites from Leaf Extracts of (Rhodomyrtus Tomentosa (Aiton) Hassk.).

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2025, v. 36, n. 2, p. 196

By:

Marwati, Marwati;
Rifai, Yusnita;
Alam, Gemini;
Yulianty, Risfah

Publication type:

Article

Targeting the p53/xCT/GSH Axis with PRIMA-1 Met Combined with Sulfasalazine Shows Therapeutic Potential in Chronic Lymphocytic Leukemia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5559, doi. 10.3390/ijms26125559

By:

Pasino, Martina;
Speciale, Andrea;
Ravera, Silvia;
Cutrona, Giovanna;
Massara, Rosanna;
Bertola, Nadia;
Viale, Maurizio;
Velkova, Irena;
Mazzarello, Andrea Nicola;
Fais, Franco;
Loiacono, Fabrizio;
Matis, Serena;
Valenti, Giulia Elda;
Traverso, Nicola;
Domenicotti, Cinzia;
Marengo, Barbara;
Tasso, Bruno;
Ibatici, Adalberto;
Angelucci, Emanuele;
Vaisitti, Tiziana

Publication type:

Article

Tumour Suppressor Genes—One Hit Can Be Enough.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 1, doi. 10.1371/journal.pbio.0020040

By:

Hohenstein, Peter

Publication type:

Article

Treatment of Terminal Peritoneal Carcinomatosis by a Transducible p53-Activating Peptide.

Published in:

PLoS Biology, 2004, v. 2, n. 2, p. 1, doi. 10.1371/journal.pbio.0020036

By:

Snyder, Eric L;
Meade, Bryan R;
Saenz, Cheryl C;
Dowdy, Steven F

Publication type:

Article

The p53 mutation spectrum in hepatocellular carcinoma from Guangxi, China : role of chronic hepatitis B virus infection and aflatoxin B1 exposure.

Published in:

Liver International, 2015, v. 35, n. 3, p. 999, doi. 10.1111/liv.12460

By:

Qi, Lu‐Nan;
Bai, Tao;
Chen, Zu‐Shun;
Wu, Fei‐Xiang;
Chen, Yuan‐Yuan;
De Xiang, Bang‐;
Peng, Tao;
Han, Ze‐Guang;
Li, Le‐Qun

Publication type:

Article

p53 mutations in human cholangiocarcinoma: a review.

Published in:

Liver International, 2005, v. 25, n. 4, p. 704, doi. 10.1111/j.1478-3231.2005.01106.x

By:

Khan, Shahid A.;
Thomas, Howard C.;
Toledano, Mireille B.;
Cox, I . Jane;
Taylor-Robinson, Simon D.

Publication type:

Article

Detection of p53 Gene by Using Genomagnetic Assay Combined with Carbon Nanotube Modified Disposable Sensor Technology.

Published in:

Electroanalysis, 2015, v. 27, n. 7, p. 1579, doi. 10.1002/elan.201400731

By:

Congur, Gulsah;
Plucnara, Medard;
Erdem, Arzum;
Fojta, Miroslav

Publication type:

Article

A Genosensor for Point Mutation Detection of P53 Gene PCR Product Using Magnetic Particles.

Published in:

Electroanalysis, 2015, v. 27, n. 6, p. 1378, doi. 10.1002/elan.201400660

By:

Hamidi‐Asl, Ezat;
Raoof, Jahan Bakhsh;
Hejazi, Mohammad Saeid;
Sharifi, Simin;
Golabi, Seyed Mahdi;
Palchetti, Ilaria;
Mascini, Marco

Publication type:

Article

ATRX loss in glioneuronal tumors with neuropil-like islands indicates similarity to diffuse astrocytic tumors.

Published in:

Journal of Neuro-Oncology, 2016, v. 130, n. 1, p. 63, doi. 10.1007/s11060-016-2224-8

By:

Kakkar, Aanchal;
Nambirajan, Aruna;
Kaur, Kavneet;
Kumar, Anupam;
Mallick, Supriya;
Suri, Vaishali;
Sarkar, Chitra;
Kale, Shashank;
Garg, Ajay;
Sharma, Mehar

Publication type:

Article

A multi-resolution textural approach to diagnostic neuropathology reporting.

Published in:

Journal of Neuro-Oncology, 2015, v. 124, n. 3, p. 393, doi. 10.1007/s11060-015-1872-4

By:

Fauzi, Mohammad;
Gokozan, Hamza;
Elder, Brad;
Puduvalli, Vinay;
Pierson, Christopher;
Otero, José;
Gurcan, Metin

Publication type:

Article

Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.

Published in:

Journal of Neuro-Oncology, 2014, v. 119, n. 1, p. 17, doi. 10.1007/s11060-014-1456-8

By:

Farooqi, Ahsan;
Dagg, Rebecca;
Choi, L.;
Shay, Jerry;
Reynolds, C.;
Lau, Loretta

Publication type:

Article

Erratum to: TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas.

Published in:

2014

By:

Gillet, Emeline;
Alentorn, Agusti;
Doukouré, Brahima;
Mundwiller, Emeline;
Thuijl, Hinke;
Reijneveld, Jaap;
Medina, José;
Liou, Amélie;
Marie, Yannick;
Mokhtari, Karima;
Hoang-Xuan, Khê;
Sanson, Marc;
Delattre, Jean-Yves;
Idbaih, Ahmed

Publication type:

Erratum

Glioblastoma with oligodendroglial component represents a subgroup of glioblastoma with high prevalence of IDH1 mutation and association with younger age.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 3, p. 439, doi. 10.1007/s11060-013-1073-y

By:

Ha, Sang;
Kang, So;
Do, In-Gu;
Suh, Yeon-Lim

Publication type:

Article

Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 3, p. 361, doi. 10.1007/s11060-012-0837-0

By:

Takano, Shingo;
Kato, Yukinari;
Yamamoto, Tetsuya;
Kaneko, Mika;
Ishikawa, Eiichi;
Tsujimoto, Yuta;
Matsuda, Masahide;
Nakai, Kei;
Yanagiya, Ryo;
Morita, Shunpei;
Tsuboi, Koji;
Matsumura, Akira

Publication type:

Article

Prolonged temozolomide for treatment of glioblastoma: preliminary clinical results and prognostic value of p53 overexpression.

Published in:

Journal of Neuro-Oncology, 2012, v. 106, n. 1, p. 127, doi. 10.1007/s11060-011-0643-0

By:

Malkoun, Nadia;
Chargari, Cyrus;
Forest, Fabien;
Fotso, Marie-Jeannette;
Cartier, Lysian;
Auberdiac, Pierre;
Thorin, Julie;
Pacaut, Cécile;
Peoc'h, Michel;
Nuti, Christophe;
Schmitt, Thierry;
Magné, Nicolas

Publication type:

Article

Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells.

Published in:

Journal of Neuro-Oncology, 2007, v. 83, n. 3, p. 249, doi. 10.1007/s11060-007-9335-1

By:

Takaya Tsuno;
Shun Katsumata;
Masaaki Mizuno;
Mitsugu Fujita;
Hirokatsu Osawa;
Norimoto Nakahara;
Yu-ichiro Satoh;
Masaki Inagaki

Publication type:

Article

Exogenous wt-p53 enhances the antitumor effect of HSV-TK/GCV on C6 glioma cells.

Published in:

Journal of Neuro-Oncology, 2007, v. 82, n. 3, p. 239, doi. 10.1007/s11060-006-9279-x

By:

Qiang Huang;
Peiyu Pu;
Zhibo Xia;
Yongping You

Publication type:

Article

All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer.

Published in:

Biotechnology Letters, 2020, v. 42, n. 6, p. 1051, doi. 10.1007/s10529-020-02847-8

By:

Dou, Yingyu;
Huang, Dongqing;
Zeng, Xiangyang;
Zhou, Yanhong;
Jiang, Xiaoyan;
Yue, Chunxue;
He, Junyu;
Xiao, Songshu

Publication type:

Article

Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00537-x

By:

Wang, Bingwu;
Gao, Jian;
Zhao, Zhongjun;
Zhong, Xuefei;
Cui, Hao;
Hou, Hui;
Zhang, Yanping;
Zheng, Junnian;
Di, Jiehui;
Liu, Yong

Publication type:

Article

Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00293-4

By:

Khan, Muhammad Babar;
Ruggieri, Rosamaria;
Jamil, Eesha;
Tran, Nhan L.;
Gonzalez, Camila;
Mugridge, Nancy;
Gao, Steven;
MacDiarmid, Jennifer;
Brahmbhatt, Himanshu;
Sarkaria, Jann N.;
Boockvar, John;
Symons, Marc

Publication type:

Article

WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00187-x

By:

Jiang, Shengqun;
Chen, Jiansu

Publication type:

Article

Resolving p53 to Create Clinically-Relevant Mutation Models.

Published in:

2023

By:

Solares, Maria J;
Jonaid, G M;
Kelly, Deborah F

Publication type:

Abstract

Dihydroquercetin improves rotenone‐induced Parkinsonism by regulating NF‐κB‐mediated inflammation pathway in rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 5, p. 1, doi. 10.1002/jbt.23022

By:

Akinmoladun, Afolabi C.;
Famusiwa, Courage D.;
Josiah, Sunday S.;
Lawal, Akeem O.;
Olaleye, Mary T.;
Akindahunsi, Afolabi A.

Publication type:

Article

P53 inhibitor pifithrin‐α inhibits ropivacaine‐induced neuronal apoptosis via the mitochondrial apoptosis pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 8, p. 1, doi. 10.1002/jbt.22822

By:

Zeng, Lian;
Zhang, Fuyu;
Zhang, Zhen;
Xu, Min;
Xu, Yang;
Liu, Ying;
Xu, Hongxia;
Sun, Xiaodong;
Sang, Ming;
Luo, Huiyu

Publication type:

Article

Anti-p53 antibodies in patients with dermatomyositis/polymyositis.

Published in:

2007

By:

Mimura, Yoshihiro;
Yazawa, Norihito;
Tamaki, Zenshirou;
Ashida, Ryuichi;
Jinnin, Masatoshi;
Asano, Yoshihide;
Tada, Yayoi;
Kubo, Masahide;
Ihn, Hironobu;
Tamaki, Kunihiko

Publication type:

Report

The utility of tumor marker combination, including serum P53 antibody, in colorectal cancer treatment.

Published in:

Surgery Today, 2017, v. 47, n. 5, p. 636, doi. 10.1007/s00595-016-1464-8

By:

Tokunaga, Ryuma;
Sakamoto, Yasuo;
Nakagawa, Shigeki;
Yoshida, Naoya;
Baba, Hideo

Publication type:

Article

Quinacrine for extremity melanoma in a mouse model of isolated limb perfusion (ILP).

Published in:

Surgery Today, 2015, v. 45, n. 3, p. 355, doi. 10.1007/s00595-014-0952-y

By:

Kim, Minhyung;
Blum, Asher;
Haslinger, Michelle;
Donahue, Michael;
Fisher, Daniel;
Skitzki, Joseph;
Park, Il

Publication type:

Article

In vitro CO-induced ROS production impairs cell cycle in SH-SY5Y neuroblastoma cells.

Published in:

Pediatric Surgery International, 2013, v. 29, n. 1, p. 51, doi. 10.1007/s00383-012-3206-3

By:

Montalto, Angela;
Currò, Monica;
Russo, Tiziana;
Visalli, Giuseppa;
Impellizzeri, Pietro;
Antonuccio, Pietro;
Arena, Salvatore;
Borruto, Francesca;
Scalfari, Gianfranco;
Ientile, Riccardo;
Romeo, Carmelo

Publication type:

Article

Differential expression of microRNAs during hepatocarcinogenesis induced by methyl deficiency in rats.

Published in:

Nutrition Reviews, 2008, v. 66, p. S33, doi. 10.1111/j.1753-4887.2008.00064.x

By:

Pogribny, Igor P.;
Tryndyak, Volodymyr P.;
Ross, Sharon A.;
Beland, Frederick A.

Publication type:

Article

Increased levels of apoptosis and p53 in partial-thickness supraspinatus tendon tears.

Published in:

Knee Surgery, Sports Traumatology, Arthroscopy, 2013, v. 21, n. 7, p. 1636, doi. 10.1007/s00167-012-2226-9

By:

Lundgreen, Kirsten;
Lian, Øystein;
Scott, Alex;
Engebretsen, Lars

Publication type:

Article

Early diversification and complex evolutionary history of the p53 tumor suppressor gene family.

Published in:

Development Genes & Evolution, 2007, v. 217, n. 11/12, p. 801, doi. 10.1007/s00427-007-0185-9

By:

Nedelcu, Aurora M.;
Tan, Christopher

Publication type:

Article

Overexpression of yeast thioredoxin TRX2 reduces p53-mediated cell death in yeast.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 20, p. 8619, doi. 10.1007/s00253-015-6886-5

By:

Kamoun, Yosra;
Mabrouk, Imed;
Delahodde, Agnes;
Boukid, Fatma;
Yacoubi-Hadj Amor, Ines;
Mokdad-Gargouri, Raja;
Gargouri, Ali

Publication type:

Article

Significance of DNA Polymerase Delta Catalytic Subunit p125 Induced by Mutant p53 in the Invasive Potential of Human Hepatocellular Carcinoma.

Published in:

Oncology, 2011, v. 79, n. 3/4, p. 229, doi. 10.1159/000322374

By:

Sanefuji, Kensaku;
Taketomi, Akinobu;
Iguchi, Tomohiro;
Sugimachi, Keishi;
Ikegami, Toru;
Yamashita, Yo-ichi;
Gion, Tomonobu;
Soejima, Yuji;
Shirabe, Ken;
Maehara, Yoshihiko

Publication type:

Article

The p53 Codon 72 Exon 4 BstUI Polymorphism and Endometrial Cancer in Caucasian Women.

Published in:

Oncology, 2009, v. 76, n. 3, p. 173, doi. 10.1159/000201570

By:

Zubor, Pavol;
Stanclova, Andrea;
Kajo, Karol;
Hatok, Jozef;
Klobusiakova, Dasa;
Visnovsky, Jozef;
Danko, Jan

Publication type:

Article

Ribosome Incorporation Induces EMT-like Phenomenon with Cell Cycle Arrest in Human Breast Cancer Cell.

Published in:

Cells Tissues Organs, 2022, v. 211, n. 2, p. 212, doi. 10.1159/000513908

By:

Kudo, Mikiko;
Anam, Mohammad Badrul;
Istiaq, Arif;
Ahmad, Shah Adil Ishtiyaq;
Ito, Naofumi;
Ohta, Kunimasa

Publication type:

Article

A UVB Fingerprint Mutation on the p53 Tumor Suppressor Gene Decreases in vitro.

Published in:

Cells Tissues Organs, 2008, v. 188, n. 3, p. 280, doi. 10.1159/000122466

By:

Zhiyuan Zhang;
Burger, Katharina;
Hellwig, Sven;
Bergemann, Jörg

Publication type:

Article

Penicilazaphilone C triggers ferroptosis in triple-negative breast cancer cells via the MDM2/p53/SLC7 A11/GPX4 pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02687-w

By:

Liang, Hua-Tao;
Huang, Feng-Ying;
Xie, Wei-Jing;
Chen, Ming-Hui;
Wu, Ri-Hong;
Dai, Shu-Zhen;
Xu, Wen-Tian;
Zheng, Wu-Ping;
Tan, Guang-Hong

Publication type:

Article

The regulatory role of PTTG1 in proliferation and migration of thyroid cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02405-6

By:

Wang, Jianjun;
Guo, Chenjun;
Cao, Junyu;
Li, Li

Publication type:

Article

Evaluation of Neutrophil Lymphocyte Ratio and IDH Mutation in Patients with Glioblastoma.

Published in:

Journal of Tepecik Education & Research Hospital / İzmir Tepecik Eğitim ve Araştırma Hastanesi Dergisi, 2023, v. 33, n. 2, p. 210, doi. 10.4274/terh.galenos.2022.59837

By:

Türk, Çağlar;
Çamlar, Mahmut

Publication type:

Article

Evaluation of lactoferrin combined hyaluronic acid formulations with the help of hyperthermia on breast cancer cell lines.

Published in:

Journal of Research in Pharmacy, 2024, v. 28, n. 5, p. 1829, doi. 10.29228/jrp.855

By:

DUMAN, Gülengül;
DEMİR, Zeynep Güneş TEPE;
KOCABAŞ, Fatih;
GİRGİN, Birkan

Publication type:

Article

IFI16 promotes human embryonic stem cell trilineage specification through interaction with p53.

Published in:

NPJ Regenerative Medicine, 2020, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41536-020-00104-0

By:

He, Qian;
Wu, Zubiao;
Yang, Wei;
Jiang, Doukou;
Hu, Chaofeng;
Yang, Xiaofei;
Li, Ning;
Li, Furong

Publication type:

Article

Evidence of micro-evolution in Crocidura russula from two abandoned heavy metal mines: potential use of Cytb, CYP1A1, and p53 as gene biomarkers.

Published in:

Ecotoxicology, 2021, v. 30, n. 10, p. 1969, doi. 10.1007/s10646-021-02472-9

By:

Quina, Ana Sofia;
Durão, Ana Filipa;
Mathias, Maria da Luz

Publication type:

Article

ABCB1 confers resistance to carboplatin by accumulating stem-like cells in the G2/M phase of the cell cycle in p53<sup>null</sup> ovarian cancer.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02435-7

By:

Lee, Danbi;
Jeong, Hyun-Seok;
Hwang, Sun-Young;
Lee, Yu-Gyeong;
Kang, Youn-Jung

Publication type:

Article