Works matching DE "OUABAIN"

Results: 226

Strophanthus sarmentosus Extracts and the Strophanthus Cardenolide Ouabain Inhibit Snake Venom Proteases from Echis ocellatus.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2625, doi. 10.3390/molecules30122625

By:

Abiola, Julius;
Aiyelaagbe, Olapeju;
Adeyi, Akindele;
Ajisebiola, Babafemi;
König, Simone

Publication type:

Article

Cardiotonic Steroids as a Potential Novel Approach for Immunomodulation in Inflammatory Bowel Disease.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 12, p. 4132, doi. 10.3390/jcm14124132

By:

Cavalcante-Silva, Luiz Henrique Agra;
Sales-Neto, José Marreiro de;
Soares, Mariana Mendonça;
Ferreira, Davi Azevedo;
Medeiros, Anna Beatriz Araujo;
Rodrigues-Mascarenhas, Sandra

Publication type:

Article

Ouabain inhibits monocyte activation in vitro: prevention of the proinflammatory mCD14+/CD16+ subset appearance and cell-size progression.

Published in:

Journal of Experimental Pharmacology, 2012, v. 4, p. 125, doi. 10.2147/JEP.S35507

By:

Valente, Raphael C.;
Araujo, Elizabeth G.;
Rumjanek, Vivian M.

Publication type:

Article

Ouabain suppresses the growth and migration abilities of glioma U-87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF-1α.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 3, p. N.PAG, doi. 10.3892/mmr.2021.11836

By:

Yang, Xiao-Sa;
Xu, Zhong-Wei;
Yi, Tai-Long;
Xu, Rui-Cheng;
Li, Jie;
Zhang, Wen-Bin;
Zhang, Sai;
Sun, Hong-Tao;
Yu, Ze-Qi;
Xu, Hao-Xiang;
Tu, Yue;
Cheng, Shi-Xiang

Publication type:

Article

Ouabain suppresses the growth and migration abilities of glioma U‑87MG cells through inhibiting the Akt/mTOR signaling pathway and downregulating the expression of HIF‑1α.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 4, p. 5595, doi. 10.3892/mmr.2018.8587

By:

Yang, Xiao-Sa;
Xu, Zhong-Wei;
Yi, Tai-Long;
Xu, Rui-Cheng;
Li, Jie;
Zhang, Wen-Bin;
Zhang, Sai;
Sun, Hong-Tao;
Yu, Ze-Qi;
Xu, Hao-Xiang;
Tu, Yue;
Cheng, Shi-Xiang

Publication type:

Article

Potassium aspartate inhibits SH-SY5Y cell damage and apoptosis induced by ouabain and H2O2.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 2, p. 2842, doi. 10.3892/mmr.2015.3741

By:

XUEFEI SUN;
DONGYU MIN;
YAN WANG;
LIYING HAO

Publication type:

Article

A real-time PCR method to genotype mutant mouse models with altered affinity for cardiotonic steroids on the Na,K-ATPase.

Published in:

PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0267348

By:

Chomczynski, Peter W.;
Vires, Kianna M.;
Rymaszewski, Michal;
Heiny, Judith A.

Publication type:

Article

Inhibitory Effect of Ouabain on Resistance to Imatinib in Chronic Myeloid Leukemia K562/G01 Cells.

Published in:

Indian Journal of Pharmaceutical Sciences, 2023, v. 85, n. 3, p. 621, doi. 10.36468/pharmaceutical-sciences.1129

By:

CHANG SUN;
LIU, J.;
SHIQI ZHAI;
LIU, H.;
PENG, L.;
JING HU

Publication type:

Article

Synaptopathy in the Aging Cochlea: Characterizing Early-Neural Deficits in Auditory Temporal Envelope Processing.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 32, p. 7108, doi. 10.1523/JNEUROSCI.3240-17.2018

By:

Parthasarathy, Aravindakshan;
Kujawa, Sharon G.

Publication type:

Article

Restoration of Dendritic Complexity, Functional Connectivity, and Diversity of Regenerated Retinal Bipolar Neurons in Adult Zebrafish.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 1, p. 120, doi. 10.1523/JNEUROSCI.3444-16.2017

By:

McGinn, Timothy E.;
Mitchell, Diana M.;
Meighan, Peter C.;
Partington, Natalie;
Leoni, Dylan C.;
Jenkins, Christina E.;
Varnum, Michael D.;
Stenkamp, Deborah L.

Publication type:

Article

Reply: Comment on 'Quiescence and yH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase': ouabain and cancer.

Published in:

British Journal of Cancer, 2013, v. 108, n. 10, p. 2191, doi. 10.1038/bjc.2013.235

By:

Hiyoshi, H;
Johnsen, J I;
Andäng, M;
Uhlén, P

Publication type:

Article

Comment on 'Quiescence and γH2AX in neuroblastoma are regulated by Ouabain/Na,K-ATPase': ouabain and cancer.

Published in:

British Journal of Cancer, 2013, v. 108, n. 10, p. 2189, doi. 10.1038/bjc.2013.234

By:

Calderón-Montaño, J M;
Burgos-Morón, E;
López-Lázaro, M

Publication type:

Article

Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase.

Published in:

British Journal of Cancer, 2012, v. 106, n. 11, p. 1807, doi. 10.1038/bjc.2012.159

By:

Hiyoshi, H;
Abdelhady, S;
Segerström, L;
Sveinbjörnsson, B;
Nuriya, M;
Lundgren, T K;
Desfrere, L;
Miyakawa, A;
Yasui, M;
Kogner, P;
Johnsen, J I;
Andäng, M;
Uhlén, P

Publication type:

Article

Role of endogenous digitalis-like factors in the clinical manifestations of severe preeclampsia: a sytematic review.

Published in:

Clinical Science, 2018, v. 132, n. 12, p. 1215, doi. 10.1042/CS20171499

By:

Buckalew, Vardaman M.

Publication type:

Article

Increased circulating levels of ouabain-like factor in patients with asymptomatic left ventricular dysfunction.

Published in:

2001

By:

Balzan, Silvana;
Neglia, Danilo;
Ghione, Sergio;
D'Urso, Giuseppina;
Baldacchino, Maria Carmela;
Montali, Umberto;
L'Abbate, Antonio;
Balzan, S;
Neglia, D;
Ghione, S;
D'Urso, G;
Baldacchino, M C;
Montali, U;
L'Abbate, A

Publication type:

journal article

Total Syntheses of Polyhydroxylated Steroids by an Unsaturation‐Functionalization Strategy.

Published in:

Angewandte Chemie, 2023, v. 135, n. 24, p. 1, doi. 10.1002/ange.202303639

By:

Sun, Jiawei;
Chen, Yuan;
Ragab, Sherif Shaban;
Gu, Wei;
Tang, Ziqiang;
Tang, Yuexun;
Tang, Wenjun

Publication type:

Article

Ouabain-stimulated trafficking regulation of the Na/K-ATPase and NHE3 in renal proximal tubule cells.

Published in:

Molecular & Cellular Biochemistry, 2012, v. 367, n. 1/2, p. 175, doi. 10.1007/s11010-012-1331-x

By:

Yan, Yanling;
Haller, Steven;
Shapiro, Anna;
Malhotra, Nathan;
Tian, Jiang;
Xie, Zijian;
Malhotra, Deepak;
Shapiro, Joseph;
Liu, Jiang

Publication type:

Article

Ouabain increases iNOS-dependent nitric oxide generation which contributes to the hypertrophic effect of the glycoside: possible role of peroxynitrite formation.

Published in:

Molecular & Cellular Biochemistry, 2012, v. 363, n. 1/2, p. 323, doi. 10.1007/s11010-011-1185-7

By:

Gan, Xiaohong;
Hunter, J.;
Huang, Cathy;
Xue, Jenny;
Rajapurohitam, Venkatesh;
Javadov, Sabzali;
Karmazyn, Morris

Publication type:

Article

A new clinical multivariable model that predicts postoperative acute kidney injury: impact of endogenous ouabain.

Published in:

Nephrology Dialysis Transplantation, 2014, v. 29, n. 9, p. 1696

By:

Simonini, Marco;
Lanzani, Chiara;
Bignami, Elena;
Casamassima, Nunzia;
Frati, Elena;
Meroni, Roberta;
Messaggio, Elisabetta;
Alfieri, Ottavio;
Hamlyn, John;
Body, Simon C.;
Collard, C. David;
Zangrillo, Alberto;
Manunta, Paolo

Publication type:

Article

Hormones.

Published in:: Nephrology Dialysis Transplantation, 2013, v. 28, n. suppl_1, p. i322, doi. 10.1093/ndt/gft127
Publication type:: Article

Ouabain and Marinobufagenin: Physiological Effects on Human Epithelial and Endothelial Cells.

Published in:

Biochemistry (00062979), 2020, v. 85, n. 4, p. 507, doi. 10.1134/S0006297920040112

By:

Klimanova, E. A.;
Fedorov, D. A.;
Sidorenko, S. V.;
Abramicheva, P. A.;
Lopina, O. D.;
Orlov, S. N.

Publication type:

Article

Low Ouabain Doses and AMP-Activated Protein Kinase as Factors Supporting Electrogenesis in Skeletal Muscle.

Published in:

Biochemistry (00062979), 2019, v. 84, n. 9, p. 1085, doi. 10.1134/S0006297919090116

By:

Kravtsova, V. V.;
Vilchinskaya, N. A.;
Rozlomii, V. L.;
Shenkman, B. S.;
Krivoi, I. I.

Publication type:

Article

Identification of proteins whose interaction with Na,K-ATPase is triggered by ouabain.

Published in:

Biochemistry (00062979), 2016, v. 81, n. 9, p. 1013, doi. 10.1134/S0006297916090108

By:

Akimova, O.;
Kapilevich, L.;
Orlov, S.;
Lopina, O.

Publication type:

Article

Effects of ouabain on proliferation of human endothelial cells correlate with Na,K-ATPase activity and intracellular ratio of Na and K.

Published in:

Biochemistry (00062979), 2016, v. 81, n. 8, p. 876, doi. 10.1134/S0006297916080083

By:

Tverskoi, A.;
Sidorenko, S.;
Klimanova, E.;
Akimova, O.;
Smolyaninova, L.;
Lopina, O.;
Orlov, S.

Publication type:

Article

Identification of a region of the polypeptide chain of Na,K-ATPase α-subunit interacting with 67-kDa melittin-like protein.

Published in:

Biochemistry (00062979), 2016, v. 81, n. 3, p. 249, doi. 10.1134/S000629791603007X

By:

Kamanina, Yu.;
Klimanova, E.;
Dergousova, E.;
Petrushanko, I.;
Lopina, O.

Publication type:

Article

Voltage-clamp measurements on single split lamellae of posterior gills of the shore crab Carcinus maenas.

Published in:

Marine Biology, 1992, v. 114, n. 3, p. 385, doi. 10.1007/BF00350028

By:

Onken, H.;
Siebers, D.

Publication type:

Article

Ouabain Modulates the Adherens Junction in Renal Epithelial Cells.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 52, n. 6, p. 1381, doi. 10.33594/000000097

By:

Castillo, Aida;
Ortuño-Pineda, Carlos;
Flores-Maldonado, Catalina;
Larre, Isabel;
Martínez Rendón, Jacqueline;
Hinojosa, Lorena;
Ponce, Arturo;
Ogazón, Alejandro;
Serrano, Mauricio;
Valdes, Jesús;
Contreras, Rubén G.;
Cereijido, Marcelino

Publication type:

Article

Inhibition of Na+/K+ ATPase blocks Zika virus infection in mice.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-1109-8

By:

Guo, Jiao;
Jia, Xiaoying;
Liu, Yang;
Wang, Shaobo;
Cao, Junyuan;
Zhang, Bo;
Xiao, Gengfu;
Wang, Wei

Publication type:

Article

In Vitro Study of the Multimodal Effect of Na + /K + ATPase Blocker Ouabain on the Tumor Microenvironment and Malignant Cells.

Published in:

Biomedicines, 2023, v. 11, n. 8, p. 2205, doi. 10.3390/biomedicines11082205

By:

Harich, Octavia-Oana;
Gavriliuc, Oana-Isabella;
Ordodi, Valentin-Laurentiu;
Tirziu, Alexandru;
Paunescu, Virgil;
Panaitescu, Carmen;
Bojin, Maria-Florina

Publication type:

Article

Na + ,K + -ATPase and Cardiotonic Steroids in Models of Dopaminergic System Pathologies.

Published in:

Biomedicines, 2023, v. 11, n. 7, p. 1820, doi. 10.3390/biomedicines11071820

By:

Markina, Alisa A.;
Kazanskaya, Rogneda B.;
Timoshina, Julia A.;
Zavialov, Vladislav A.;
Abaimov, Denis A.;
Volnova, Anna B.;
Fedorova, Tatiana N.;
Gainetdinov, Raul R.;
Lopachev, Alexander V.

Publication type:

Article

Ouabain Reverts CUS-Induced Disruption of the HPA Axis and Avoids Long-Term Spatial Memory Deficits.

Published in:

Biomedicines, 2023, v. 11, n. 4, p. 1177, doi. 10.3390/biomedicines11041177

By:

Leite, Jacqueline Alves;
Orellana, Ana Maria;
Andreotti, Diana Zukas;
Matumoto, Amanda Midori;
de Souza Ports', Natacha Medeiros;
de Sá Lima, Larissa;
Kawamoto, Elisa Mitiko;
Munhoz, Carolina Demarchi;
Scavone, Cristoforo

Publication type:

Article

Effect of Ouabain on Glutamate Transport in the Hippocampus of Rats with LPS-Induced Neuroinflammation.

Published in:

Biomedicines, 2023, v. 11, n. 3, p. 920, doi. 10.3390/biomedicines11030920

By:

Garcia, Israel José Pereira;
Kinoshita, Paula Fernanda;
Valadares, Jéssica Martins de Moura;
Carvalho, Luciana Estefani Drumond de;
Cortes, Vanessa Faria;
Barbosa, Leandro Augusto;
Scavone, Cristoforo;
Santos, Hérica de Lima

Publication type:

Article

毒毛花苷通过 Nrf2 抑制子宫内膜癌细胞增殖活性.

Published in:

Progress in Modern Biomedicine, 2022, v. 22, n. 12, p. 2208, doi. 10.13241/j.cnki.pmb.2022.12.002

By:

陈佩琴;
吕牧;
黄宝珠;
张箴波;
李静婕

Publication type:

Article

Ab initio conformational analysis of marinobufagenin molecule and molecular targets of the action of cardiotonic steroids.

Published in:

Russian Journal of Organic Chemistry, 2015, v. 51, n. 11, p. 1620, doi. 10.1134/S1070428015110172

By:

Rogachevskii, I.;
Shelykh, T.;
Podzorova, S.;
Krylov, B.;
Plakhova, V.

Publication type:

Article

Short-, middle- and long-term safety of superparamagnetic iron oxide-labeled allogeneic bone marrow stromal cell transplantation in rat model of lacunar infarction.

Published in:

Neuropathology, 2015, v. 35, n. 3, p. 197, doi. 10.1111/neup.12180

By:

Tan, Chengbo;
Shichinohe, Hideo;
Abumiya, Takeo;
Nakayama, Naoki;
Kazumata, Ken;
Hokari, Masaaki;
Hamauchi, Shuji;
Houkin, Kiyohiro

Publication type:

Article

Unveiling the Role of Cholesterol in Subnanomolar Ouabain Rescue of Cortical Neurons from Calcium Overload Caused by Excitotoxic Insults.

Published in:

Cells (2073-4409), 2023, v. 12, n. 15, p. 2011, doi. 10.3390/cells12152011

By:

Sibarov, Dmitry A.;
Zhuravleva, Zoia D.;
Ilina, Margarita A.;
Boikov, Sergei I.;
Stepanenko, Yulia D.;
Karelina, Tatiana V.;
Antonov, Sergei M.

Publication type:

Article

Hypercontractile Cardiac Phenotype in Mice with Migraine-Associated Mutation in the Na + ,K + -ATPase α 2 -Isoform.

Published in:

Cells (2073-4409), 2023, v. 12, n. 8, p. 1108, doi. 10.3390/cells12081108

By:

Rajanathan, Rajkumar;
Riera, Clàudia Vilaseca i;
Pedersen, Tina Myhre;
Staehr, Christian;
Bouzinova, Elena V.;
Nyengaard, Jens Randel;
Thomsen, Morten B.;
Bøtker, Hans Erik;
Matchkov, Vladimir V.

Publication type:

Article

Ouabain Counteracts Retinal Ganglion Cell Death Through Modulation of BDNF and IL-1 Signaling Pathways.

Published in:

Brain Sciences (2076-3425), 2025, v. 15, n. 2, p. 123, doi. 10.3390/brainsci15020123

By:

Oliveira, Amanda Candida da Rocha;
Figueiredo, Camila Saggioro;
Raony, Ícaro;
Von-Held-Ventura, Juliana Salles;
Granja, Marcelo Gomes;
Mázala-de-Oliveira, Thalita;
Pedrosa-Soares, Vinícius Henrique;
dos Santos, Aline Araujo;
Giestal-de-Araujo, Elizabeth

Publication type:

Article

Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.684316

By:

Du, Jie;
Jiang, Lijun;
Chen, Fuqiang;
Hu, Huantao;
Zhou, Meijuan

Publication type:

Article

Divergent Electrophysiologic Effects of Sacubitril in Digitalis- and Pinacidil-Related Shortened Repolarization: Experimental Evidence for Harmful Effects of Digitalis Glycosides.

Published in:

Pharmaceutics, 2025, v. 17, n. 3, p. 338, doi. 10.3390/pharmaceutics17030338

By:

Ellermann, Christian;
Mengel, Carlo;
Wolfes, Julian;
Wegner, Felix K.;
Rath, Benjamin;
Reinke, Florian;
Eckardt, Lars;
Frommeyer, Gerrit

Publication type:

Article

Astrocytes Reduce Store-Operated Ca 2+ Entry in Microglia under the Conditions of an Inflammatory Stimulus and Muscarinic Receptor Blockade.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 12, p. 1521, doi. 10.3390/ph15121521

By:

Kim, Yoo Jin;
Shin, You Kyoung;
Seo, Eunhye;
Seol, Geun Hee

Publication type:

Article

Specific and dynamic detection of palytoxins by in vitro microplate assay with human neuroblastoma cells.

Published in:

Bioscience Reports, 2009, v. 29, n. 1, p. 13, doi. 10.1042/BSR20080080

By:

ESPIÑA, Begoña;
CAGIDE, Eva;
Carmen LOUZAO, M.;
FERNANDEZ, Maria M.;
VIEYTES, Mercedes R.;
KATIKOU, Panagiota;
VILLAR, Adriano;
JAEN, David;
MAMAN, Luz;
BOTANA, Luis M.

Publication type:

Article

Ouabain inhibits RAW264.7 cells proliferation and induces apoptosis via Bcl-2 and bax expression.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2018, v. 31, n. 5, p. 1997

By:

Yi Luo;
Hongxia Qin;
Lin Zhao;
Long Jin;
Anan Jiang;
Xuewei Li;
Mingzhou Li;
Xun Wang

Publication type:

Article

Comparative Cardiotoxicity of Low Doses of Digoxin, Ouabain, and Oleandrin.

Published in:

Cardiovascular Toxicology, 2020, v. 20, n. 6, p. 539, doi. 10.1007/s12012-020-09579-1

By:

Botelho, Ana F. M.;
Miranda, Ana L. S.;
Freitas, Thalita G.;
Milani, Paula F.;
Barreto, Tatiane;
Cruz, Jáder S.;
Melo, Marília M.

Publication type:

Article

The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0871-y

By:

Legrand, Cyril;
Saleppico, Roberto;
Sticht, Jana;
Lolicato, Fabio;
Müller, Hans-Michael;
Wegehingel, Sabine;
Dimou, Eleni;
Steringer, Julia P.;
Ewers, Helge;
Vattulainen, Ilpo;
Freund, Christian;
Nickel, Walter

Publication type:

Article

Involvement of IL-1β and IL-6 in antiarrhythmic properties of atorvastatin in ouabain-induced arrhythmia in rats.

Published in:

Immunopharmacology & Immunotoxicology, 2018, v. 40, n. 3, p. 256, doi. 10.1080/08923973.2018.1440592

By:

Najjari, Mahya;
Vaezi, Gholamhassan;
Hojati, Vida;
Mousavi, Zahra;
Bakhtiarian, Azam;
Nikoui, Vahid

Publication type:

Article

Ouabain-Induced Cochlear Degeneration in Rat.

Published in:

Neurotoxicity Research, 2012, v. 22, n. 2, p. 158, doi. 10.1007/s12640-012-9320-0

By:

Fu, Yong;
Ding, Dalian;
Jiang, Haiyan;
Salvi, Richard

Publication type:

Article

cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria.

Published in:

Korean Journal of Physiology & Pharmacology, 2016, v. 20, n. 1, p. 9, doi. 10.4196/kjpp.2016.20.1.9

By:

Li-qun Peng;
Ping Li;
Qiu-li Zhang;
Lan Hong;
Li-ping Liu;
Xun Cui;
Bai-ri Cui

Publication type:

Article

Antiviral activity of ouabain against a Brazilian Zika virus strain.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14243-5

By:

Carvalho, Deyse Cristina Madruga;
da Silva, Poliana Gomes;
Dantas, Willyenne Marília;
da Silva, Severino Jefferson Ribeiro;
da Silva, Caroline Targino Alves;
Chaves, Elton José Ferreira;
de Araújo, Demetrius Antônio Machado;
de Oliveira, Ronaldo Nascimento;
Rodrigues-Mascarenhas, Sandra;
Pena, Lindomar José

Publication type:

Article

Role of the Rhamnosyl Residue of Ouabain in the Activation of the Na,K-ATPase Signaling Function.

Published in:

Life (2075-1729), 2023, v. 13, n. 7, p. 1500, doi. 10.3390/life13071500

By:

Rogachevskii, Ilya V.;
Samosvat, Dmitriy M.;
Penniyaynen, Valentina A.;
Plakhova, Vera B.;
Podzorova, Svetlana A.;
Ma, Ke;
Zegrya, Georgy G.;
Krylov, Boris V.

Publication type:

Article