Works matching DE "ORGANIC cation transporters"

Results: 502

Molecular pharmacokinetic mechanism of JBP485 against aristolochic acid I (AAI) -induced nephrotoxicity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1577942

By:

Wang, Chong;
Jin, Huan;
Wang, Changyuan;
Wu, Jingjing;
Meng, Qiang;
Zhong, Ming;
Sun, Huijun;
Wei, Yuheng;
Gao, Ge;
Kaku, Taiichi;
Huo, Xiaokui;
Liu, Kexin

Publication type:

Article

Antituberculosis potential of borrelidin derivatives: An in silico molecular docking and molecular dynamic approach.

Published in:

Thai Journal of Pharmaceutical Sciences, 2025, v. 49, n. 1, p. 1

By:

Ernawati, Teni;
Ramadhan, Donny;
Hermawan, Faris;
Wulyoadi, Sasmito;
Marwoto, Bambang;
Wibisana, Ahmad;
Srijanto, Bambang

Publication type:

Article

A narrative review of the neuropharmacology of synthetic cathinones—Popular alternatives to classical drugs of abuse.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2023, v. 38, n. 3, p. 1, doi. 10.1002/hup.2866

By:

Kuropka, Patryk;
Zawadzki, Marcin;
Szpot, Paweł

Publication type:

Article

DFT calculation of the interplay effects between cation–π and intramolecular hydrogen bond interactions of mesalazine drug with selected transition metal ions (Mn+, Fe2+, Co+, Ni2+, Cu+, Zn2+)

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2021, v. 140, n. 8, p. 1, doi. 10.1007/s00214-021-02813-1

By:

Mohammadi, Marziyeh;
Alirezapour, Fahimeh;
Khanmohammadi, Azadeh

Publication type:

Article

Silicon reduces lead accumulation in Moso bamboo via immobilization and suppression of metal cation transporter genes in roots.

Published in:

Tree Physiology, 2025, v. 45, n. 1, p. 1, doi. 10.1093/treephys/tpaf002

By:

Yang, Fan;
Xie, Xuanhong;
Zhao, Yu;
Jin, Zetao;
Pan, Xianyu;
Shen, Zhenming;
Hu, Lin;
Yu, Xuejun;
Shao, Ji Feng

Publication type:

Article

Diabetic macular edema with neuroretinal detachment: OCT and OCT-angiography biomarkers of treatment response to anti-VEGF and steroids.

Published in:

Acta Diabetologica, 2020, v. 57, n. 3, p. 287, doi. 10.1007/s00592-019-01424-4

By:

Vujosevic, Stela;
Toma, Caterina;
Villani, Edoardo;
Muraca, Andrea;
Torti, Emanuele;
Florimbi, Giordana;
Leporati, Francesco;
Brambilla, Marco;
Nucci, Paolo;
De Cilla', Stefano

Publication type:

Article

The conditional stimulation of rat organic cation transporter 2, but not its human ortholog, by mesoridazine: the possibility of the involvement of the high-affinity binding site of the transporter in the stimulation.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 11, p. 1513, doi. 10.1111/jphp.12799

By:

Hyung, Sungwoo;
Pyeon, Wonji;
Park, Ji Eun;
Song, Yoo Kyung;
Chung, Suk Jae

Publication type:

Article

L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides.

Published in:

Journal of Pharmacy & Pharmacology, 2016, v. 68, n. 9, p. 1160, doi. 10.1111/jphp.12574

By:

Futatsugi, Azusa;
Masuo, Yusuke;
Kawabata, Shiori;
Nakamichi, Noritaka;
Kato, Yukio

Publication type:

Article

Insights Into Genetic Variations of the OCT1 Gene in Metformin Poor Responders Among Bangladeshi Type 2 Diabetic Patients.

Published in:

Advances in Pharmacological & Pharmaceutical Sciences, 2025, v. 2025, p. 1, doi. 10.1155/adpp/8568658

By:

Begum, Rokeya;
Das, Arindita;
Alam, Md. Jahangir;
Sultana, Gazi Nurun Nahar;
Mudigonda, Koteshwara

Publication type:

Article

Ion Chromatography for Small Molecule Determination in Clinical and Pharmaceutical Studies.

Published in:

LC-GC Europe, 2019, v. 32, n. 12, p. 629

By:

Michalski, Rajmund;
Błażewicz, Anna;
Kończyk, Joanna;
Krupa, Katarzyna;
Niziński, Przemysław

Publication type:

Article

In silico modeling for ex vivo placenta perfusion of nicotinef.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1275467

By:

Harvey Ho;
Shengjie Zhang;
Ken Kurosawa;
Botao Jiang;
Koji Chiba

Publication type:

Article

Impairment of exocytotic transmitter release by decynium-22 through an inhibition of ion channels.

Published in:

Frontiers in Pharmacology, 2023, p. 01, doi. 10.3389/fphar.2023.1276100

By:

Haar, Gabriele;
Hrachova, Katsiaryna;
Wagner, Tanja;
Boehm, Stefan;
Schicker, Klaus

Publication type:

Article

L-carnitine prevents lenvatinib-induced muscle toxicity without impairment of the anti-angiogenic efficacy.

Published in:

Frontiers in Pharmacology, 2023, v. 14, p. 01, doi. 10.3389/fphar.2023.1182788

By:

Zheng Jing;
Tomohiro Iba;
Hisamichi Naito;
Pingping Xu;
Jun-ichi Morishige;
Naoto Nagata;
Hironao Okubo;
Hitoshi Ando

Publication type:

Article

Preparation and characterization of intestinal transporter -targeted polymeric micelles.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2018, v. 27, n. 7, p. 490, doi. 10.5246/jcps.2018.07.050

By:

Chuyu He;
Yao Jin;
Yunqiang Deng;
Yang Zou;
Shidi Han;
Chuhang Zhou;
Yuanhang Zhou;
Xinru Li;
Yanxia Zhou;
Yan Liu

Publication type:

Article

Structural basis of promiscuous substrate transport by Organic Cation Transporter 1.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42086-9

By:

Zeng, Yi C.;
Sobti, Meghna;
Quinn, Ada;
Smith, Nicola J.;
Brown, Simon H. J.;
Vandenberg, Jamie I.;
Ryan, Renae M.;
O'Mara, Megan L.;
Stewart, Alastair G.

Publication type:

Article

Investigation of intercalation of diphenhydramine into the interlayer of smectite by XRD, FTIR, TG-DTG analyses and molecular simulation.

Published in:

Arabian Journal of Chemistry, 2017, v. 10, n. 6, p. 855, doi. 10.1016/j.arabjc.2015.04.016

By:

Lv, Guocheng;
Chang, Po-Hsiang;
Xing, Xuebing;
Jiang, Wei-Teh;
Jean, Jiin-Shuh;
Li, Zhaohui

Publication type:

Article

Vibrational Response of Methylammonium Lead Iodide: From Cation Dynamics to Phonon-Phonon Interactions.

Published in:

ChemSusChem, 2016, v. 9, n. 20, p. 2994, doi. 10.1002/cssc.201600932

By:

Ivanovska, Tanja;
Quarti, Claudio;
Grancini, Giulia;
Petrozza, Annamaria;
De Angelis, Filippo;
Milani, Alberto;
Ruani, Giampiero

Publication type:

Article

Atomistic description of the OCTN1 recognition mechanism via in silico methods.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0304512

By:

Ben Mariem, Omar;
Palazzolo, Luca;
Torre, Beatrice;
Wei, Yao;
Bianchi, Davide;
Guerrini, Uliano;
Laurenzi, Tommaso;
Saporiti, Simona;
De Fabiani, Emma;
Pochini, Lorena;
Indiveri, Cesare;
Eberini, Ivano

Publication type:

Article

Ergothioneine and central nervous system diseases.

Published in:

Neurochemical Research, 2022, v. 47, n. 9, p. 2513, doi. 10.1007/s11064-022-03665-2

By:

Nakamichi, Noritaka;
Tsuzuku, Sota;
Shibagaki, Fumiya

Publication type:

Article

On the Role of a Conserved Methionine in the Na+-Coupling Mechanism of a Neurotransmitter Transporter Homolog.

Published in:

Neurochemical Research, 2022, v. 47, n. 1, p. 163, doi. 10.1007/s11064-021-03253-w

By:

Zhou, Wenchang;
Trinco, Gianluca;
Slotboom, Dirk J.;
Forrest, Lucy R.;
Faraldo-Gómez, José D.

Publication type:

Article

Homostachydrine is a Xenobiotic Substrate of OCTN1/SLC22A4 and Potentially Sensitizes Pentylenetetrazole-Induced Seizures in Mice.

Published in:

Neurochemical Research, 2020, v. 45, n. 11, p. 2664, doi. 10.1007/s11064-020-03118-8

By:

Nishiyama, Misa;
Nakamichi, Noritaka;
Yoshimura, Tomoyuki;
Masuo, Yusuke;
Komori, Tomoe;
Ishimoto, Takahiro;
Matsuo, Jun-ichi;
Kato, Yukio

Publication type:

Article

Carnitine/Organic Cation Transporter OCTN1 Negatively Regulates Activation in Murine Cultured Microglial Cells.

Published in:

Neurochemical Research, 2018, v. 43, n. 1, p. 107, doi. 10.1007/s11064-017-2350-5

By:

Ishimoto, Takahiro;
Nakamichi, Noritaka;
Nishijima, Hikari;
Masuo, Yusuke;
Kato, Yukio

Publication type:

Article

Regional Characteristics of Histamine Uptake into Neonatal Rat Astrocytes.

Published in:

Neurochemical Research, 2013, v. 38, n. 7, p. 1348, doi. 10.1007/s11064-013-1028-x

By:

Perdan-Pirkmajer, Katja;
Pirkmajer, Sergej;
Raztresen, Andreja;
Krzan, Mojca

Publication type:

Article

Association between the organic cation transporter 3 methylation and hepatocellular carcinoma.

Published in:

Indian Journal of Biochemistry & Biophysics, 2023, v. 60, n. 3, p. 224, doi. 10.56042/ijbb.v60i3.57578

By:

Heidari, Zahra;
Asemi-Rad, Azam;
Moudi, Bita;
Mahmoudzadeh-Sagheb, Hamidreza

Publication type:

Article

In reference to Immunohistochemical localization of OCT2 in the cochlea of various species.

Published in:

2016

By:

Ciarimboli, Giuliano

Publication type:

Letter

In response to Immunohistochemical localization of OCT2 in the cochlea of various species.

Published in:

2016

By:

Hellberg, Victoria;
Gahm, Caroline;
Ehrsson, Hans;
Liu, Wei;
Rask‐Andersen, Helge;
Laurell, Göran;
Rask-Andersen, Helge;
Laurell, Göran

Publication type:

Letter

Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by ) and Organic Cation Transporter 1 (OCT1) (Encoded by ) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study.

Published in:

2019

By:

Dawed, Adem Y.;
Kaixin Zhou;
van Leeuwen, Nienke;
Mahajan, Anubha;
Robertson, Neil;
Koivula, Robert;
Elders, Petra J. M.;
Rauh, Simone P.;
Jones, Angus G.;
Holl, Reinhard W.;
Stingl, Julia C.;
Franks, Paul W.;
McCarthy, Mark I.;
‘t Hart, Leen M.;
Pearson, Ewan R.;
Zhou, Kaixin;
't Hart, Leen M;
IMI DIRECT Consortium

Publication type:

journal article

Metformin for Gestational Diabetes Mellitus: Progeny, Perspective, and a Personalized Approach.

Published in:

2019

By:

Barbour, Linda A.;
Feig, Denice S.

Publication type:

journal article

Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.

Published in:

PLoS Genetics, 2019, v. 15, n. 5, p. 1, doi. 10.1371/journal.pgen.1007687

By:

Vázquez-Arreguín, Karina;
Bensard, Claire;
Schell, John C.;
Swanson, Eric;
Chen, Xinjian;
Rutter, Jared;
Tantin, Dean

Publication type:

Article

Multiple binding sites in organic cation transporters require sophisticated procedures to identify interactions of novel drugs.

Published in:

Biological Chemistry, 2019, v. 400, n. 2, p. 195, doi. 10.1515/hsz-2018-0191

By:

Koepsell, Hermann

Publication type:

Article

Tropane alkaloids as substrates and inhibitors of human organic cation transporters of the SLC22 (OCT) and the SLC47 (MATE) families.

Published in:

Biological Chemistry, 2017, v. 398, n. 2, p. 237, doi. 10.1515/hsz-2016-0236

By:

Jiayin Chen;
Brockmöller, Jürgen;
Seitz, Tina;
König, Jörg;
Tzvetkov, Mladen V.;
Xijing Chen

Publication type:

Article

Effects of cisplatin and acacetin on total antioxidant status, apoptosis and expression of OCTN3 in mouse testis.

Published in:

Biotechnic & Histochemistry, 2022, v. 97, n. 3, p. 185, doi. 10.1080/10520295.2021.1925347

By:

Ghanbari, Ali;
Jalili, Cyrus;
Abdolmaleki, Amir;
Shokri, Vahid

Publication type:

Article

Restoring Perivascular Adipose Tissue Function in Obesity Using Exercise.

Published in:

Cardiovascular Drugs & Therapy, 2021, v. 35, n. 6, p. 1291, doi. 10.1007/s10557-020-07136-0

By:

Saxton, Sophie N;
Toms, Lauren K;
Aldous, Robert G;
Withers, Sarah B;
Ohanian, Jacqueline;
Heagerty, Anthony M

Publication type:

Article

Major Cardiac–Psychiatric Drug–Drug Interactions: a Systematic Review of the Consistency of Drug Databases.

Published in:

Cardiovascular Drugs & Therapy, 2021, v. 35, n. 3, p. 441, doi. 10.1007/s10557-020-06979-x

By:

Castaldelli-Maia, João Mauricio;
Hofmann, Caio;
Chagas, Antonio Carlos Palandri;
Liprandi, Alvaro Sosa;
Alcocer, Alejandro;
Andrade, Laura H.;
Wielgosz, Andreas

Publication type:

Article

Significance of OCT1 Expression in Acute Myeloid Leukemia.

Published in:

Pathology & Oncology Research, 2017, v. 23, n. 3, p. 665, doi. 10.1007/s12253-016-0161-7

By:

Stefanko, Ewa;
Rybka, Justyna;
Jaźwiec, Bożena;
Haus, Olga;
Stąpor, Sylwia;
Kuliczkowski, Kazimierz;
Wróbel, Tomasz

Publication type:

Article

Organic-Cation Modulated Assembly Behaviors of a Ureidopyrimidone-Grafting Cluster.

Published in:

Molecules, 2023, v. 28, n. 9, p. 3677, doi. 10.3390/molecules28093677

By:

Jiang, Fengrui;
Wang, Jiaxu;
Li, Bao;
Wu, Lixin

Publication type:

Article

Antidiabetic and Renoprotective Effects of Coffea arabica Pulp Aqueous Extract through Preserving Organic Cation Transport System Mediated Oxidative Stress Pathway in Experimental Type 2 Diabetic Rats.

Published in:

Molecules, 2021, v. 26, n. 7, p. 1907, doi. 10.3390/molecules26071907

By:

Boonphang, Oranit;
Ontawong, Atcharaporn;
Pasachan, Tipthida;
Phatsara, Manussabhorn;
Duangjai, Acharaporn;
Amornlerdpison, Doungporn;
Jinakote, Metee;
Srimaroeng, Chutima;
Chin, Young-won;
Choi, Young Hee;
Kim, Hojun

Publication type:

Article

In Vitro Interaction of AB-FUBINACA with Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes and Drug Transporters.

Published in:

Molecules, 2020, v. 25, n. 19, p. 4589, doi. 10.3390/molecules25194589

By:

Kim, Sunjoo;
Kim, Dong Kyun;
Shin, Yongho;
Jeon, Ji-Hyeon;
Song, Im-Sook;
Lee, Hye Suk

Publication type:

Article

Effects of Exercise Training on Renal Carnitine Biosynthesis and Uptake in the High-Fat and High-Sugar-Fed Mouse.

Published in:

Molecules, 2020, v. 25, n. 9, p. 2100, doi. 10.3390/molecules25092100

By:

Upadhyay, Aman;
Al-Nakkash, Layla;
Broderick, Tom L.;
Indiveri, Cesare;
Console, Lara;
Hichami, Aziz

Publication type:

Article

SLC22A5 (OCTN2) Carnitine Transporter—Indispensable for Cell Metabolism, a Jekyll and Hyde of Human Cancer.

Published in:

Molecules, 2020, v. 25, n. 1, p. 14, doi. 10.3390/molecules25010014

By:

Juraszek, Barbara;
Nałęcz, Katarzyna A.;
Indiveri, Cesare;
Console, Lara

Publication type:

Article

In Vitro Inhibitory Effects of APINACA on Human Major Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Drug Transporters.

Published in:

Molecules, 2019, v. 24, n. 16, p. 3000, doi. 10.3390/molecules24163000

By:

Kim, Sunjoo;
Choi, Won-Gu;
Kwon, Mihwa;
Lee, Sowon;
Cho, Yong-Yeon;
Lee, Joo Young;
Kang, Han Chang;
Song, Im-Sook;
Lee, Hye Suk;
Gütschow, Michael

Publication type:

Article

An integrative approach to cisplatin chronic toxicities in mice reveals importance of organic cation-transporter-dependent protein networks for renoprotection.

Published in:

Archives of Toxicology, 2019, v. 93, n. 10, p. 2835, doi. 10.1007/s00204-019-02557-9

By:

Hucke, Anna;
Rinschen, Markus M.;
Bauer, Oliver B.;
Sperling, Michael;
Karst, Uwe;
Köppen, Christina;
Sommer, Karolin;
Schröter, Rita;
Ceresa, Cecilia;
Chiorazzi, Alessia;
Canta, Annalisa;
Semperboni, Sara;
Marmiroli, Paola;
Cavaletti, Guido;
Schlatt, Stefan;
Schlatter, Eberhard;
Pavenstädt, Hermann;
Heitplatz, Barbara;
Van Marck, Veerle;
Sparreboom, Alex

Publication type:

Article

Nature of histamine transport in neonatal rat cultured type 1 astrocytes – organic cation transporters are not involved.

Published in:

Inflammation Research, 2009, v. 58, n. 0, p. 32, doi. 10.1007/s00011-009-0655-9

By:

K. Perdan;
Z. Kobe;
M. Kržan

Publication type:

Article

The era of combination of nephroprotective agents in CKD is there.

Published in:

Nephrology Dialysis Transplantation, 2025, v. 40, p. i1, doi. 10.1093/ndt/gfae260

By:

Jadoul, Michel;
Rossing, Peter

Publication type:

Article

Beyond SGLT2: proximal tubule transporters as potential drug targets for chronic kidney disease.

Published in:

Nephrology Dialysis Transplantation, 2025, v. 40, p. i18, doi. 10.1093/ndt/gfae211

By:

Wagner, Carsten A

Publication type:

Article

A quest for protecting kidneys from cisplatin toxicity.

Published in:

Nephrology Dialysis Transplantation, 2019, v. 34, n. 10, p. 1623, doi. 10.1093/ndt/gfz029

By:

Viggiano, Davide;
Capasso, Anna;
Capasso, Giovambattista

Publication type:

Article

Thioacetamide-Induced Acute Liver Injury Increases Metformin Plasma Exposure by Downregulating Renal OCT2 and MATE1 Expression and Function.

Published in:

Biomedicines, 2023, v. 11, n. 12, p. 3314, doi. 10.3390/biomedicines11123314

By:

Zhi, Hao;
Dai, Yidong;
Su, Lin;
Yang, Lu;
Wu, Wenhan;
Wang, Zehua;
Zhu, Xinyue;
Liu, Li;
Aa, Jiye;
Yang, Hanyu

Publication type:

Article

SLC22A3 rs2048327 Polymorphism Is Associated with Diabetic Retinopathy in Caucasians with Type 2 Diabetes Mellitus.

Published in:

Biomedicines, 2023, v. 11, n. 8, p. 2303, doi. 10.3390/biomedicines11082303

By:

Grbić, Emin;
Globočnik Petrovič, Mojca;
Cilenšek, Ines;
Petrovič, Danijel

Publication type:

Article

Association of SLC22A1 , SLC22A2 , SLC47A1 , and SLC47A2 Polymorphisms with Metformin Efficacy in Type 2 Diabetic Patients.

Published in:

Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102546

By:

Chen, Peixian;
Cao, Yumin;
Chen, Shenren;
Liu, Zhike;
Chen, Shiyi;
Guo, Yali

Publication type:

Article

Using Ex Vivo Porcine Jejunum to Identify Membrane Transporter Substrates: A Screening Tool for Early—Stage Drug Development.

Published in:

Biomedicines, 2020, v. 8, n. 9, p. 340, doi. 10.3390/biomedicines8090340

By:

Arnold, Yvonne E.;
Kalia, Yogeshvar N.

Publication type:

Article