Works matching DE "ORGANIC anion transporters"

Results: 663

Caution with PBPK Modeling Based on the In Vitro Kinetics for Bilirubin Hepatic Uptake and Glucuronidation: Commentary on Dong et al.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 2, p. 301, doi. 10.1002/cpt.3734

By:

Miners, John O.;
Polasek, Thomas M.

Publication type:

Article

Inhibition of OATP1B1/3 Rather Than UGT1A1 May Be the Major Cause of the Bilirubin Elevation After Atazanavir Administration.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 2, p. 497, doi. 10.1002/cpt.3529

By:

Dong, Jin;
Sharma, Pradeep;
Emara, Rasha;
Cheung, Derek;
Tang, Weifeng;
Zhou, Diansong;
Boulton, David W.;
Någård, Mats;
Park, Miki S.

Publication type:

Article

Inactivation of Thyroid Hormone Transporters Mct8/Oatp1c1 in Mouse Brain Endothelial Cells Causes Region-Specific Alterations in Central Thyroid Hormone Signaling.

Published in:

Thyroid, 2025, v. 35, n. 7, p. 816, doi. 10.1089/thy.2025.0089

By:

Alevyzaki, Androniki;
Markova, Boyka;
De Angelis, Meri;
Müller, Timo D.;
Chandrasekar, Akila;
Müller-Fielitz, Helge;
Schwaninger, Markus;
Boelen, Anita;
Führer, Dagmar;
Mayerl, Steffen;
Heuer, Heike

Publication type:

Article

Decitabine regulates the resistance of HCC to sorafenib through demethylation.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01925-w

By:

Zhang, Miao;
Zhou, Xiaolei;
Li, Zhenzhen;
Zhao, TianYu;
Miao, Yu;
Liu, Sen;
Han, Qiaoqiao;
Wang, Libo;
Xu, Yongdeng;
Cui, Tao;
Wang, Ze;
Yi, Xiulin;
Yan, Fengying;
Wang, Xiaoliang

Publication type:

Article

Protein-bound uremic toxin clearance as biomarker of kidney tubular function in diabetic kidney disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07248-3

By:

Ahmed, Sabbir;
Sparidans, Rolf W.;
Vernooij, Robin W. M.;
Mihaila, Silvia M.;
Broekhuizen, Roel;
Goldschmeding, Roel;
Nguyen, Tri Q.;
Masereeuw, Rosalinde;
Gerritsen, Karin G. F.

Publication type:

Article

Impaired N-linked glycosylation of uptake and efflux transporters in human non-alcoholic fatty liver disease.

Published in:

Liver International, 2017, v. 37, n. 7, p. 1074, doi. 10.1111/liv.13362

By:

Clarke, John D.;
Novak, Petr;
Lake, April D.;
Hardwick, Rhiannon N.;
Cherrington, Nathan J.

Publication type:

Article

The key role of organic anion transporter 3 in the drug–drug interaction between tranilast and methotrexate.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 4, p. 1, doi. 10.1002/jbt.22983

By:

Wang, Jingjing;
Yuan, Wenjing;
Shen, Qingqing;
Wu, Qipeng;
Jiang, Zhenzhou;
Wu, Wei;
Zhang, Luyong;
Huang, Xin

Publication type:

Article

Interactions between cyazofamid and human drug transporters.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 4, p. 1, doi. 10.1002/jbt.22459

By:

Song, Im‐Sook;
Jeong, Hyeon‐Uk;
Choi, Min‐Koo;
Kwon, Mihwa;
Shin, Yongho;
Kim, Jeong Han;
Lee, Hye‐Suk

Publication type:

Article

Digital clubbing, joint pain, and skin changes in a young man: primary hypertrophic osteoarthropathy.

Published in:

2022

By:

González, Luis Alonso;
Quintero-González, Diana Carolina;
Vanegas-García, Adriana Lucía

Publication type:

Case Study

Hepatobiliary-phase gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid MRI for pretreatment prediction of efficacy-to-standard-therapies based on Barcelona Clinic Liver Cancer algorithm: an up-to-date review.

Published in:

European Radiology, 2023, v. 33, n. 12, p. 8764, doi. 10.1007/s00330-023-09950-0

By:

Minamiguchi, Kiyoyuki;
Irizato, Mariko;
Uchiyama, Tomoko;
Taiji, Ryosuke;
Nishiofuku, Hideyuki;
Marugami, Nagaaki;
Tanaka, Toshihiro

Publication type:

Article

Gadoxetic acid-enhanced MR imaging for hepatocellular carcinoma: molecular and genetic background.

Published in:

2020

By:

Kitao, Azusa;
Matsui, Osamu;
Yoneda, Norihide;
Kozaka, Kazuto;
Kobayashi, Satoshi;
Koda, Wataru;
Inoue, Dai;
Ogi, Takahiro;
Yoshida, Kotaro;
Gabata, Toshifumi

Publication type:

journal article

Gadoxetate-enhanced MR imaging and compartmental modelling to assess hepatocyte bidirectional transport function in rats with advanced liver fibrosis.

Published in:

2017

By:

Giraudeau, Céline;
Leporq, Benjamin;
Doblas, Sabrina;
Lagadec, Matthieu;
Pastor, Catherine;
Daire, Jean-Luc;
Beers, Bernard;
Giraudeau, Céline;
Pastor, Catherine M;
Van Beers, Bernard E

Publication type:

journal article

Quantitative assessment of hepatic function: modified look-locker inversion recovery (MOLLI) sequence for T1 mapping on Gd-EOB-DTPA-enhanced liver MR imaging.

Published in:

2016

By:

Yoon, Jeong;
Lee, Jeong;
Paek, Munyoung;
Han, Joon;
Choi, Byung;
Yoon, Jeong Hee;
Lee, Jeong Min;
Han, Joon Koo;
Choi, Byung Ihn

Publication type:

journal article

Genotype and allele frequencies of SLCO1B1 g.89595 T>C polymorphism in a healthy Turkish population.

Published in:

Journal of Research in Pharmacy, 2019, v. 23, n. 6, p. 1149, doi. 10.35333/jrp.2019.80

By:

UÇKUN ŞAHİNOĞULLARI, Zuhal;
CANACANKATAN, Necmiye;
CANACANKATAN, Mehmet

Publication type:

Article

VHL-dependence of EHHADH Expression in a Human Renal Cell Carcinoma Cell Line.

Published in:

Journal of Kidney Cancer & VHL, 2024, v. 11, n. 1, p. 12, doi. 10.15586/jkcvhl.v11i1.322

By:

Pilz, Julia Felicitas;
Klein, Marinella;
Neumann-Haefelin, Elke;
Ganner, Athina

Publication type:

Article

Genetically encoded green fluorescent sensor for probing sulfate transport activity of solute carrier family 26 member a2 (Slc26a2) protein.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07020-9

By:

Lai, Cuixin;
Yang, Lina;
Pathiranage, Vishaka;
Wang, Ruizhao;
Subach, Fedor V.;
Walker, Alice R.;
Piatkevich, Kiryl D.

Publication type:

Article

IP3R at ER-Mitochondrial Contact Sites: Beyond the IP3R-GRP75-VDAC1 Ca2+ Funnel.

Published in:

Contact (25152564), 2023, v. 6, p. 1, doi. 10.1177/25152564231181020

By:

Atakpa-Adaji, Peace;
Ivanova, Adelina

Publication type:

Article

Publisher Correction: Interactomic exploration of LRRC8A in volume-regulated anion channels.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02123-y

By:

Carpanese, Veronica;
Festa, Margherita;
Prosdocimi, Elena;
Bachmann, Magdalena;
Sadeghi, Soha;
Bertelli, Sara;
Stein, Frank;
Velle, Angelo;
Abdel-Salam, Mostafa A. L.;
Romualdi, Chiara;
Pusch, Michael;
Checchetto, Vanessa

Publication type:

Article

Novel Clinical Updates in Uremia.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 13, p. 3791, doi. 10.3390/jcm11133791

By:

Clementi, Anna;
Virzì, Grazia Maria

Publication type:

Article

Adaptive Mechanisms of Renal Bile Acid Transporters in a Rat Model of Carbon Tetrachloride-Induced Liver Cirrhosis.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 3, p. 636, doi. 10.3390/jcm11030636

By:

Donadei, Chiara;
Angeletti, Andrea;
Cappuccilli, Maria;
Conti, Massimiliano;
Conte, Diletta;
Zappulo, Fulvia;
De Giovanni, Alessio;
Malvi, Deborah;
Aldini, Rita;
Roda, Aldo;
La Manna, Gaetano

Publication type:

Article

Acidosis Activates the Nrf2 Pathway in Renal Proximal Tubule-Derived Cells through a Crosstalk with Renal Fibroblasts.

Published in:

Antioxidants, 2023, v. 12, n. 2, p. 412, doi. 10.3390/antiox12020412

By:

Schulz, Marie-Christin;
Dubourg, Virginie;
Nolze, Alexander;
Kopf, Michael;
Schwerdt, Gerald;
Gekle, Michael

Publication type:

Article

Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.89635

By:

Xiaoxuan Lin;
Haller, Patrick R.;
Bavi, Navid;
Faruk, Nabil;
Perozo, Eduardo;
Sosnick, Tobin R.

Publication type:

Article

The urinary excretion of an organic anion transporter as an early biomarker of methotrexate-induced kidney injury.

Published in:

Toxicology Research, 2016, v. 5, n. 2, p. 530, doi. 10.1039/c5tx00436e

By:

Severin, María J.;
Trebucobich, Mara S.;
Buszniez, Patricia;
Brandoni, Anabel;
Torres, Adriana M.

Publication type:

Article

A systematic review of the drug-drug interaction between Statins and Quinolones.

Published in:

BMC Pharmacology & Toxicology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s40360-024-00760-8

By:

Zhou, Jifang;
Yu, Lixia;
Xu, Huimin

Publication type:

Article

Pharmacokinetics and Safety of Atogepant Co‐administered with Quinidine Gluconate in Healthy Participants: A Phase 1, Open‐Label, Drug‐Drug Interaction Study.

Published in:

Clinical Pharmacology in Drug Development, 2024, v. 13, n. 8, p. 930, doi. 10.1002/cpdd.1407

By:

Boinpally, Ramesh;
Borbridge, Lisa;
Wangsadipura, Veronica

Publication type:

Article

Evaluation of the Clinical Drug‐Drug Interaction Potential of Pritelivir on Transporters and CYP450 Enzymes Using a Cocktail Approach.

Published in:

Clinical Pharmacology in Drug Development, 2024, v. 13, n. 7, p. 755, doi. 10.1002/cpdd.1408

By:

de Vries, Michiel;
Bonsmann, Susanne;
Pausch, Jörg;
Sumner, Melanie;
Birkmann, Alexander;
Zimmermann, Holger;
Kropeit, Dirk

Publication type:

Article

Pharmacokinetic Interaction of Chiglitazar with CYP3A4 Inducer or Inhibitor: An Open‐Label, Sequential Crossover, Self‐Control, 3‐Period Study in Healthy Chinese Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2023, v. 12, n. 2, p. 168, doi. 10.1002/cpdd.1198

By:

Yuan, Fei;
Li, Jing;
Li, Xuening;
Li, Hui;
Chen, Weili;
Yang, Mengjie;
Chen, Hanjing;
Sheng, Lei;
Liu, Chao;
Wu, Yujia;
Xu, Hongrong

Publication type:

Article

Drug‐Drug Interaction of Letermovir and Atorvastatin in Healthy Participants.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 4, p. 420, doi. 10.1002/cpdd.1071

By:

McCrea, Jacqueline B.;
Menzel, Karsten;
Adedoyin, Adedayo;
Cho, Carolyn R.;
Fox‐Bosetti, Sabrina;
Macha, Sreeraj;
Zhao, Tian;
Liu, Fang;
Panebianco, Deborah;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Assessment of Pharmacokinetic Interaction Between Gefapixant (MK‐7264), a P2X3 Receptor Antagonist, and the OATP1B1 Drug Transporter Substrate Pitavastatin.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 3, p. 406, doi. 10.1002/cpdd.1047

By:

McCrea, Jacqueline B.;
Hussain, Azher;
Ma, Bennett;
Garrett, Graigory C.;
Evers, Raymond;
Laabs, John E.;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Surveys/Research Exploring Japanese Phase I Studies in Global Drug Development: Are They Necessary Prior to Joining Global Clinical Trials?

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1410, doi. 10.1002/cpdd.1044

By:

Hirano, Masaru;
Yamada, Masanori;
Tanaka, Toshiaki;
Koue, Toshiko;
Saito, Tomohisa;
Higashimori, Mitsuo;
Ochiai, Hisao;
Yamamoto, Junichi;
Yaguchi, Saori;
Mita, Sachiko;
Hara, Katsutoshi

Publication type:

Article

Napabucasin Drug‐Drug Interaction Potential, Safety, Tolerability, and Pharmacokinetics Following Oral Dosing in Healthy Adult Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 8, p. 824, doi. 10.1002/cpdd.961

By:

Dai, Xiaoshu;
Karol, Michael D.;
Hitron, Matthew;
Hard, Marjie L.;
Goulet, Matthew T.;
McLaughlin, Colleen F.;
Brantley, Scott J.

Publication type:

Article

Molecular pharmacokinetic mechanism of JBP485 against aristolochic acid I (AAI) -induced nephrotoxicity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1577942

By:

Wang, Chong;
Jin, Huan;
Wang, Changyuan;
Wu, Jingjing;
Meng, Qiang;
Zhong, Ming;
Sun, Huijun;
Wei, Yuheng;
Gao, Ge;
Kaku, Taiichi;
Huo, Xiaokui;
Liu, Kexin

Publication type:

Article

Basic characterization of antibodies targeting receptors of the tumor necrosis factor receptor superfamily.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1115667

By:

Zaitseva, Olena;
Anany, Mohamed;
Wajant, Harald;
Lang, Isabell

Publication type:

Article

Unmeasured Organic Anions as Predictors of Clinical Outcomes in Lactic Acidosis due to Sepsis.

Published in:

Journal of Intensive Care Medicine, 2023, v. 38, n. 10, p. 975, doi. 10.1177/08850666231177602

By:

Hussain, Marvi;
Zaki, Kirollos E.;
Asef, Mark A.;
Song, Hubert;
Treger, Richard M.

Publication type:

Article

Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50121-6

By:

Li, Yinzheng;
Wang, Zheng;
Xu, Huzi;
Hong, Yu;
Shi, Mengxia;
Hu, Bin;
Wang, Xiuru;
Ma, Shulin;
Wang, Meng;
Cao, Chujin;
Zhu, Han;
Hu, Danni;
Xu, Chang;
Lin, Yanping;
Xu, Gang;
Yao, Ying;
Zeng, Rui

Publication type:

Article

A Review on Abrocitinib Drug Clinical Study.

Published in:

2022

By:

Chouhan, Satish;
Meena, Manish

Publication type:

Case Study

Proteome profile differences among human, monkey, and mouse brain microvessels and cultured brain microvascular endothelial cells.

Published in:

Fluids & Barriers of the CNS, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12987-025-00650-z

By:

Kumabe, Haruka;
Masuda, Takeshi;
Ito, Shingo;
Furihata, Tomomi;
Toda, Akiko;
Mogi, Masayuki;
Araki, Norie;
Ohtsuki, Sumio

Publication type:

Article

The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells.

Published in:

Fluids & Barriers of the CNS, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12987-024-00544-6

By:

Svane, Nana;
Pedersen, Alberte Bay Villekjær;
Rodenberg, Anne;
Ozgür, Burak;
Saaby, Lasse;
Bundgaard, Christoffer;
Kristensen, Mie;
Tfelt-Hansen, Peer;
Brodin, Birger

Publication type:

Article

The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression.

Published in:

Journal of Drug Delivery, 2014, p. 1, doi. 10.1155/2014/129849

By:

Taylor-Wells, Jennina;
Meredith, David

Publication type:

Article

Mechanism of flavonoids in the treatment of gouty arthritis (Review).

Published in:

Molecular Medicine Reports, 2024, v. 30, n. 2, p. N.PAG, doi. 10.3892/mmr.2024.13256

By:

Liu, Feifan;
Bai, Yuanmei;
Wan, Yan;
He, Jinglin;
Li, Qiongchao;
Xie, Yuhuan;
Guo, Peixin

Publication type:

Article

SLC26A6 and NADC-1: Future direction of nephrolithiasis and calculus-related hypertension research.

Published in:

Molecular Medicine Reports, 2021, v. 24, n. 5, p. N.PAG, doi. 10.3892/mmr.2021.12385

By:

Yang, Xingyue;
Yao, Shun;
An, Jiaxing;
Jin, Hai;
Wang, Hui;
Tuo, Biguang

Publication type:

Article

CTHRC1 and PD-1/PD-L1 expression predicts tumor recurrence in prostate cancer.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 5, p. 4244, doi. 10.3892/mmr.2019.10690

By:

Zhou, Qing;
Xiong, Wei;
Zhou, Xing;
Gao, Rui-Song;
Lin, Qun-Fang;
Liu, Hui-Ying;
Li, Juan-Ni;
Tian, Xue-Fei

Publication type:

Article

Folic acid reverses uric acid crystal-induced surface OAT1 internalization by inhibiting RhoA activity in uric acid nephropathy.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 3, p. 2385, doi. 10.3892/mmr.2016.4837

By:

XINLIN WU;
JIANXIANG LIU;
JIANQING ZHANG;
HENG LIU;
MIANSHENG YAN;
BIRONG LIANG;
HONGBO XIE;
SHIJUN ZHANG;
BAOGUO SUN;
HOUMING ZHOU

Publication type:

Article

Near-infrared fluorescence imaging of prostate cancer using heptamethine carbocyanine dyes.

Published in:

Molecular Medicine Reports, 2015, v. 11, n. 2, p. 821, doi. 10.3892/mmr.2014.2815

By:

JIANLIN YUAN;
XIAOMIN YI;
FEI YAN;
FULI WANG;
WEIJUN QIN;
GUOJUN WU;
XIAOJIAN YANG;
CHEN SHAO;
CHUNG, LELAND W. K.

Publication type:

Article

Probenecid Inhibits Respiratory Syncytial Virus (RSV) Replication.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 5, p. 912, doi. 10.3390/v14050912

By:

Murray, Jackelyn;
Bergeron, Harrison C.;
Jones, Les P.;
Reener, Zachary Beau;
Martin, David E.;
Sancilio, Fred D.;
Tripp, Ralph A.

Publication type:

Article

Islatravir Is Not Expected to Be a Victim or Perpetrator of Drug-Drug Interactions via Major Drug-Metabolizing Enzymes or Transporters.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 8, p. 1566, doi. 10.3390/v13081566

By:

Bleasby, Kelly;
Houle, Robert;
Hafey, Michael;
Lin, Meihong;
Guo, Jingjing;
Lu, Bing;
Sanchez, Rosa I.;
Fillgrove, Kerry L.

Publication type:

Article

Development of a Pharmacokinetic Model That Accounts for the Plasma Concentrations of Conjugated and Unconjugated Bilirubin Observed in a Variety of Disease States.

Published in:

Clinical & Experimental Gastroenterology, 2023, v. 16, p. 277, doi. 10.2147/CEG.S438140

By:

Levitt, David G;
Levitt, Michael D

Publication type:

Article

Resistance to cisplatin-induced cell death conferred by the activity of organic anion transporting polypeptides ( OATP) in human melanoma cells.

Published in:

Pigment Cell & Melanoma Research, 2013, v. 26, n. 4, p. 592, doi. 10.1111/pcmr.12108

By:

Silvy, Françoise;
Lissitzky, Jean‐Claude;
Bruneau, Nadine;
Zucchini, Nathalie;
Landrier, Jean‐François;
Lombardo, Dominique;
Verrando, Patrick

Publication type:

Article

Non‐invasive visualization of epidermal hypertrophy of pachydermoperiostosis.

Published in:

Journal of the European Academy of Dermatology & Venereology, 2023, v. 37, n. 3, p. e344, doi. 10.1111/jdv.18654

By:

Komatsu‐Fujii, Takayoshi;
de Jesus, Corrine Sison;
Nomura, Takashi;
Kabashima, Kenji

Publication type:

Article

Does Ethnic Variability Exist in the Systemic Exposures of OATP1A2 Substrates-Fexofenadine in Taiwanese?

Published in:

Indian Journal of Pharmaceutical Sciences, 2015, v. 77, n. 5, p. 573, doi. 10.4103/0250-474X.169032

By:

CHEN, Y. A.;
JUAN, C. H.;
HSU, K. Y.

Publication type:

Article