Works matching DE "O6-Methylguanine-DNA Methyltransferase"
Results: 381
Development and Validation of a Prognostic Molecular Phenotype and Clinical Characterization in Grade III Diffuse Gliomas Treatment with Radio-Chemotherapy.
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- Therapeutics & Clinical Risk Management, 2025, v. 21, p. 35, doi. 10.2147/TCRM.S478905
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- Article
Novel Pathways of Oxidative and Nitrosative Inactivation of the Human MGMT Protein in Colon Cancer and Glioblastoma Cells: Increased Efficacy of Alkylating Agents In Vitro and In Vivo.
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- Diseases, 2025, v. 13, n. 2, p. 32, doi. 10.3390/diseases13020032
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- Article
The prognostic importance of glioblastoma size and shape.
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- Acta Neurochirurgica, 2024, v. 166, n. 1, p. 1, doi. 10.1007/s00701-024-06351-0
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- Article
MGMT methylation and its prognostic significance in inoperable IDH-wildtype glioblastoma: the MGMT-GBM study.
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- Acta Neurochirurgica, 2024, v. 166, n. 1, p. 1, doi. 10.1007/s00701-024-06300-x
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- Article
Mutant TP53 enhances the resistance of glioblastoma cells to temozolomide by up-regulating O-methylguanine DNA-methyltransferase.
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- Neurological Sciences, 2013, v. 34, n. 8, p. 1421, doi. 10.1007/s10072-012-1257-9
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- Article
Effect of segmentation dimension on radiomics analysis for MGMT promoter methylation status in gliomas.
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- Current Neurology / Aktualno?ci Neurologiczne, 2024, v. 24, n. 1, p. 8, doi. 10.15557/AN.2024.0002
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- Article
Deep learning classification of MGMT status of glioblastomas using multiparametric MRI with a novel domain knowledge augmented mask fusion approach.
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- Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-87803-0
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- Article
Prognosis prediction via histological evaluation of cellular heterogeneity in glioblastoma.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-76826-8
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- Article
Preoperative prediction of MGMT promoter methylation in glioblastoma based on multiregional and multi-sequence MRI radiomics analysis.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-66653-2
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- Article
Evaluation of the clinical use of MGMT methylation in extracellular vesicle-based liquid biopsy as a tool for glioblastoma patient management.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-62061-8
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- Article
Infratentorial Stereotactic Biopsy of Brainstem and Cerebellar Lesions.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 11, p. 1432, doi. 10.3390/brainsci11111432
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- Article
MGMT Expression Contributes to Temozolomide Resistance in H3K27M-Mutant Diffuse Midline Gliomas.
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- Frontiers in Oncology, 2020, v. 9, p. 1, doi. 10.3389/fonc.2019.01568
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- Article
O<sup>6</sup>-Methylguanine-DNA Methyltransferase (MGMT): Challenges and New Opportunities in Glioma Chemotherapy.
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- Frontiers in Oncology, 2020, v. 9, p. 1, doi. 10.3389/fonc.2019.01547
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- Publication type:
- Article
Case Report: Clinical Outcome and Image Response of Two Patients With Secondary High-Grade Glioma Treated With Chemoradiation, PCV, and Cannabidiol.
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- 2019
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- Publication type:
- Case Study
Detection of a Double-Stranded MGMT Gene Using Electrochemically Reduced Graphene Oxide (ErGO) Electrodes Decorated with AuNPs and Peptide Nucleic Acids (PNA).
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- Biosensors (2079-6374), 2022, v. 12, n. 2, p. 98, doi. 10.3390/bios12020098
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- Article
Elevated Serum IL-6 as a Negative Prognostic Biomarker in Glioblastoma: Integrating Bioinformatics and Clinical Validation.
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- Journal of Cancer, 2025, v. 16, n. 3, p. 802, doi. 10.7150/jca.104759
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- Article
MGMT gene silencing by promoter hypermethylation in gastric cancer in a high incidence area.
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- Cellular Oncology (2211-3428), 2014, v. 37, n. 4, p. 245, doi. 10.1007/s13402-014-0179-3
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- Article
Co-expression prognostic-related genes signature base on propofol and sevoflurane anesthesia predict prognosis and immunotherapy response in glioblastoma.
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- Annals of Medicine, 2023, v. 55, n. 1, p. 778, doi. 10.1080/07853890.2023.2171109
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- Article
Chlorpromazine induces cytotoxic autophagy in glioblastoma cells via endoplasmic reticulum stress and unfolded protein response.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-02144-w
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- Article
Differential gene expression-based connectivity mapping identified novel drug candidate and improved Temozolomide efficacy for Glioblastoma.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-02135-x
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- Article
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-01889-8
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- Article
Downregulation of lncRNA ZNF582-AS1 due to DNA hypermethylation promotes clear cell renal cell carcinoma growth and metastasis by regulating the N(6)-methyladenosine modification of MT-RNR1.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-01889-8
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- Publication type:
- Article
Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy-the MecMeth/NOA-24 trial.
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- 2022
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- Publication type:
- journal article
Molecular features of glioblastomas in long-term survivors compared to short-term survivors-a matched-pair analysis.
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- 2022
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- Publication type:
- journal article
Predominance of MGMT promoter methylation among Pakistani glioblastoma patients.
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- Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09363-2
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- Article
Investigation of promoter methylation patterns association with genes expression profile of ISL1, MGMT and DMNT3b in tissue of breast cancer patients.
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- Molecular Biology Reports, 2022, v. 49, n. 2, p. 847, doi. 10.1007/s11033-021-06546-z
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- Article
Does increase in DNA repair allow 'Tolerance-to-Insult' in chemical carcinogenesis? Skin tumor experiments with MGMT-overexpressing mice.
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- Environmental & Molecular Mutagenesis, 2014, v. 55, n. 2, p. 145, doi. 10.1002/em.21834
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- Article
Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells.
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- Molecular Medicine, 2019, v. 25, n. 1, p. 1, doi. 10.1186/s10020-019-0116-z
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- Publication type:
- Article
Mutagenicity and toxicity of the DNA alkylation carcinogens 1, 2-dimethylhydrazine and azoxymethane in Escherichia coli and Salmonella typhimurium.
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- Mutagenesis, 1996, v. 11, n. 3, p. 241, doi. 10.1093/mutage/11.3.241
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- Article
The Association between O(6)-Methylguanine DNA Methyltransferase (<italic>MGMT</italic>) rs11016879 and rs7069143 Polymorphisms and Susceptibility to Еsophageal Аdenocarcinoma in a Han Chinese Population.
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- Russian Journal of Genetics, 2018, v. 54, n. 4, p. 494, doi. 10.1134/S1022795418040063
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- Article
Combination Treatment with Theranostic Nanoparticles for Glioblastoma Sensitization to TMZ.
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- Molecular Imaging & Biology, 2014, v. 16, n. 5, p. 680, doi. 10.1007/s11307-014-0734-3
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- Article
Genome-wide association analyses of ovarian cancer patients undergoing primary debulking surgery identify candidate genes for residual disease.
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- NPJ Genomic Medicine, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41525-024-00395-y
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- Article
MGMT Methylation Is Associated with Human Papillomavirus Infection in Cervical Dysplasia: A Longitudinal Study.
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- Journal of Clinical Medicine, 2023, v. 12, n. 19, p. 6188, doi. 10.3390/jcm12196188
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- Article
Identification of MGMT Downregulation Induced by miRNA in Glioblastoma and Possible Effect on Temozolomide Sensitivity.
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- Journal of Clinical Medicine, 2023, v. 12, n. 5, p. 2061, doi. 10.3390/jcm12052061
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- Article
Predicting MGMT Promoter Methylation in Diffuse Gliomas Using Deep Learning with Radiomics.
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- Journal of Clinical Medicine, 2022, v. 11, n. 12, p. 3445, doi. 10.3390/jcm11123445
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- Article
Therapeutic Anticoagulation Impacts MR Morphologic Recurrence Patterns in Glioblastoma—A Matched-Pair Analysis.
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- Journal of Clinical Medicine, 2022, v. 11, n. 2, p. 422, doi. 10.3390/jcm11020422
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- Article
Association of IDH1 Mutation and MGMT Promoter Methylation with Clinicopathological Parameters in an Ethnically Diverse Population of Adults with Gliomas in England.
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- Biomedicines, 2024, v. 12, n. 12, p. 2732, doi. 10.3390/biomedicines12122732
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- Article
MGMT Promoter Methylation as a Prognostic Factor in Primary Glioblastoma: A Single-Institution Observational Study.
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- Biomedicines, 2022, v. 10, n. 8, p. N.PAG, doi. 10.3390/biomedicines10082030
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- Publication type:
- Article
DNA Hypermethylation Involves in the Down-Regulation of Chloride Intracellular Channel 4 (CLIC4) Induced by Photodynamic Therapy.
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- Biomedicines, 2021, v. 9, n. 8, p. 927, doi. 10.3390/biomedicines9080927
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- Article
On the Critical Issues in Temozolomide Research in Glioblastoma: Clinically Relevant Concentrations and MGMT-independent Resistance.
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- 2019
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- Publication type:
- Letter
MGMT promoter methylation in serum and cerebrospinal fluid as a tumor-specific biomarker of glioma.
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- Biomedical Reports, 2015, v. 3, n. 4, p. 543, doi. 10.3892/br.2015.462
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- Publication type:
- Article
Abnormal promoter methylation of multiple tumor suppressor genes in human bronchial epithelial malignant cells.
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- Biomedical Reports, 2014, v. 2, n. 4, p. 525, doi. 10.3892/br.2014.268
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- Article
Inhibitory effect of alpinetin on IL‐6 expression by promoting cytosine methylation in CpG islands in the IL‐6 promoter region.
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- Molecular Genetics & Genomic Medicine, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1002/mgg3.993
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- Article
Radiomics and MGMT promoter methylation for prognostication of newly diagnosed glioblastoma.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50849-y
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- Article
MGMT Promoter Methylation: Prognostication beyond Treatment Response.
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- Journal of Personalized Medicine, 2023, v. 13, n. 6, p. 999, doi. 10.3390/jpm13060999
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- Article
Paths of Evolution of Progressive Anaplastic Meningiomas: A Clinical and Molecular Pathology Study.
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- Journal of Personalized Medicine, 2023, v. 13, n. 2, p. 206, doi. 10.3390/jpm13020206
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- Article
Salivary DNA Methylation as an Epigenetic Biomarker for Head and Neck Cancer. Part II: A Cancer Risk Meta-Analysis.
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- Journal of Personalized Medicine, 2021, v. 11, n. 7, p. 606, doi. 10.3390/jpm11070606
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- Article
Prevalence of single-nucleotide variants in twenty-five pharmacogenes from a Cuban sample cohort.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1467036
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- Article
Prevalence of single-nucleotide variants in twenty-five pharmacogenes from a Cuban sample cohort.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1467036
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- Publication type:
- Article
Prevalence of single-nucleotide variants in twenty-five pharmacogenes from a Cuban sample cohort.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1467036
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- Publication type:
- Article